Academic literature on the topic 'Resuscitation Orders'

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Journal articles on the topic "Resuscitation Orders"

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Bowman, Sallyann M. "Resuscitation Orders." Annals of Internal Medicine 111, no. 12 (December 15, 1989): 1046. http://dx.doi.org/10.7326/0003-4819-111-12-1046_1.

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Alison, DL. "Resuscitation and non-resuscitation orders." Palliative Medicine 8, no. 1 (January 1994): 79. http://dx.doi.org/10.1177/026921639400800113.

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Skinner, Andrew. "Resuscitation and non-resuscitation orders." Palliative Medicine 8, no. 4 (October 1994): 338–39. http://dx.doi.org/10.1177/026921639400800413.

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Swartz, Conrad M., and Carole Stewart. "Melancholia and Orders to Restrict Resuscitation." Psychiatric Services 42, no. 2 (February 1991): 189–91. http://dx.doi.org/10.1176/ps.42.2.189.

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Sritharan, Gaya, Amber C. Mills, Michele R. Levinson, and Anthea L. Gellie. "Doctors’ attitudes regarding not for resuscitation orders." Australian Health Review 41, no. 6 (2017): 680. http://dx.doi.org/10.1071/ah16161.

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Objectives The aims of the present study were to investigate doctors’ attitudes regarding the discussion and writing of not for resuscitation (NFR) orders and to identify potential barriers to the completion of these orders. Methods A questionnaire-based convenience study was undertaken at a tertiary hospital. Likert scales and open-ended questions were directed to issues surrounding the discussion, timing, understanding and writing of NFR orders, including legal and personal considerations. Results Doctors thought the presence of an NFR order both should and does alter care delivered by nursing staff, particularly delivery of pain relief, nursing observations and contacting the medical emergency team. Eighty-five per cent of doctors believed they needed somebody else’s consent to write an NFR order (seeking of consent is not a requirement in most Australian jurisdictions). Conclusion There are complex barriers to the writing and implementation of NFR orders, including doctors’ knowledge around the need for consent when cardiopulmonary resuscitation is likely to be futile or excessively burdensome. Doctors also believed that NFR orders result in changes to goals-of-care, suggesting a confounding of NFR orders with palliative care. Furthermore, doctors are willing to write NFR orders where there is clear medical indication and the patient is imminently dying, but are otherwise reliant on patients and family to initiate discussion. What is known about the topic? Hospitalised elderly patients, in the absence of an NFR order, are known to have poor survival and outcomes following resuscitation. Further, Australian data on the prevalence of NFR forms show that only a minority of older in-patients have a written NFR order in their history. In Australian hospitals, NFR orders are completed by doctors. What does this paper add? To our knowledge, the present study is the first in Australia to qualitatively analyse doctors’ reasons to writing NFR orders. The open-text nature of this questioning has been important in eliciting doctors’ responses without hypothesis guessing bias. Further, we add to the literature on the breadth of considerations doctors may encounter with regard to NFR orders. What are the implications for practitioners? The findings indicate the issues impeding decision making around cardiopulmonary resuscitation relate to poor knowledge of the law, particularly around the issue of consent and confounding NFR orders with provision of palliative care. Such barriers to the completion of NFR orders expose elderly in-patients to futile and burdensome resuscitation events. The findings suggest consideration be given to education and training materials to inform doctors about jurisdictional law regarding resuscitation documentation, support decision making around cardiopulmonary resuscitation and promote goals-of-care discussions on admission.
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Halliwell, Amanda. "DNAR orders during the pandemic." Practice Management 31, no. 1 (January 2, 2021): 32–35. http://dx.doi.org/10.12968/prma.2021.31.1.32.

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The Care Quality Commission was commissioned by the Department of Health and Social care to review do not attempt resuscitation decision-making during the Covid-19 pandemic. Amanda Halliwell reviews their interim report
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Kalkman, Shona, Lotty Hooft, Johanne M. Meijerman, Johannes T. A. Knape, and Johannes J. M. van Delden. "Survival after Perioperative Cardiopulmonary Resuscitation." Anesthesiology 124, no. 3 (March 1, 2016): 723–29. http://dx.doi.org/10.1097/aln.0000000000000873.

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Abstract Automatic suspension of do-not-resuscitate (DNR) orders during general anesthesia does not sufficiently address a patient’s right to self-determination and is a practice still observed among anesthesiologists today. To provide an evidence base for ethical management of DNR orders during anesthesia and surgery, the authors performed a systematic review of the literature to quantify the survival after perioperative cardiopulmonary resuscitation (CPR). Results show that the probability of surviving perioperative CPR ranged from 32.0 to 55.7% when measured within the first 24 h after arrest with a neurologically favorable outcome expectancy between 45.3 and 66.8% at follow-up, which suggests a viable survival of approximately 25%. Because CPR generally proves successful in less than 15% of out-of-hospital cardiac arrests, the altered outcome probabilities that the conditions in the operating room bring on warrant reevaluation of DNR orders during the perioperative period. By preoperatively communicating the evidence to patients, they can make better informed decisions while reducing the level of moral distress that anesthesiologists may experience when certain patients decide to retain their DNR orders.
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Griffith, Richard. "Consultation before ‘do not attempt resuscitation’ orders." British Journal of Nursing 28, no. 13 (July 11, 2019): 886–87. http://dx.doi.org/10.12968/bjon.2019.28.13.886.

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Morrison, Wynne, and Ivor Berkowitz. "Do Not Attempt Resuscitation Orders in Pediatrics." Pediatric Clinics of North America 54, no. 5 (October 2007): 757–71. http://dx.doi.org/10.1016/j.pcl.2007.06.005.

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Micallef, S., M. Skrifvars, and M. J. Parr. "Barriers to documenting not-for-resuscitation orders." Resuscitation 81, no. 2 (December 2010): S33—S34. http://dx.doi.org/10.1016/j.resuscitation.2010.09.143.

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Dissertations / Theses on the topic "Resuscitation Orders"

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Baptista, Filipa Duarte. "Percepções e práticas de desempenho profissional de veterinários portugueses perante a ressuscitação cardiopulmonar-cerebral." Bachelor's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2009. http://hdl.handle.net/10400.5/1248.

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Dissertação de Mestrado Integrado em Medicina Veterinária
A ideia do presente trabalho surgiu no contexto do estágio curricular realizado na Clínica Veterinária das Laranjeiras e tem como objectivo a análise das percepções e práticas de desempenho profissional de veterinários portugueses perante a ressuscitação cardiopulmonarcerebral (RCPC) e perceber a relação das percepções e práticas com a experiência profissional. Foi distribuído um inquérito adaptado de um original americano em 8 hospitais veterinários na grande Lisboa, Porto, Algarve e Glasgow (Escócia), o qual foi preenchido por 34 veterinários portugueses. Os dados foram inseridos e tratados pelo programa estatístico SPSS 17.0®, para descrição de frequências de respostas e cruzamento de dados entre as respostas e a experiência profissional (estabelecendo o coeficiente de correlação de Spearman). Como resultados e conclusões, verificaram-se respostas muito diversificadas das taxas de sucesso da RCPC percebidas pelos inquiridos, o que poderá ter sido pela ausência de definição de paragem cardiopulmonar (PCP). Também se concluiu que na maioria das instituições participantes não existe um documento formal para os donos referindo-se à decisão de não reanimação (DNR), assim como em cerca de metade não existe a possibilidade do dono formalizar de forma escrita o seu desejo de não reanimação. Contudo, a maioria dos inquiridos reconhece a importância da manifestação dos desejos do dono embora a questão apenas se coloque informalmente e somente quando surgem problemas com os animais. Adicionalmente, verificou-se que a maioria dos respondentes avança para a RCPC quando não conhece os desejos de DNR dos donos. Posto isto, a ausência de mecanismos de discussão e formalização de DNR pode levar à prática de reanimações que não são necessárias ou que são inadequadas. Cerca de metade dos inquiridos sente-se adequadamente preparado para liderar uma RCPC e a maioria afirma estar preparado para intervir numa RCPC. Existe por parte dos inquiridos o reconhecimento da diferença entre a capacidade de liderar e de intervir numa RCPC, e possivelmente de diferente nível de conhecimentos e sistematização das metodologias de RCPC. Este resultado sugere a necessidade de formação e treino especializado de forma a alcançar a confiança necessária para a liderança num cenário de RCPC, para decidir criteriosamente e objectivamente quando cessar os esforços de reanimação, para minimizar o impacto negativo de uma RCPC falhada e também confiança para lidar com os sentimentos dos donos quando é necessário discutir com eles RCPC e DNR.
ABSTRACT - Perceptions and professional practices of Portuguese veterinarians towards cardiopulmonarycerebral resuscitation -- The idea for this study came up during a traineeship held at Clínica Veterinária das Laranjeiras (Lisbon) and aims to analyze the perceptions and practices of professional performance of Portuguese veterinarians in cardiopulmonary-cerebral resuscitation (CPCR) and to understand the relationship of perceptions and practices with professional experience. The purpose of this study is to understand the Portuguese actuality in the subject of cardiopulmonary-cerebral resuscitation. To this end, a questionnaire was adapted from an American original and distributes in 8 veterinary hospitals in Lisbon, Porto, Algarve and Glasgow (Scotland), which was completed by 34 Portuguese veterinarians. Data was entered and processed by the statistical program SPSS 17.0 for description of frequency response and crosschecking between the responses and professional experience (establishing the Spearman correlation coefficient). There were many different answers about success rates of CPCR perceived by respondents, which may have been because the lack of definition of cardiopulmonary arrest (CPA). It was observed that in most of the participating institutions, there is no formal documentation for the owners referring to do not attempt resuscitation (DNAR) orders, and in about half, the possibility of the owner to formalize in writing his DNAR orders exists. However, most respondents acknowledged the importance of expressing the owner’s wishes, even though the question only takes place informally, and only when problems with the animal arise. Additionally, most respondents perform CPCR when they don’t know the wishes of DNAR of the owners, which, given the lack of mechanisms for discussion and formalization of DNAR, may lead to the practice of unwanted or inappropriate CPCR. About half of respondents feel that they adequately prepared to supervise a CPCR and most of them state being prepared to intervene in a CPCR. The respondents recognize the difference between the ability to lead and to intervene in a CPCR, and possibly different levels of knowledge and training of CPCR. This result suggests the need for specific training in order to achieve the confidence needed for leadership in a setting of CPCR, to objectively decide when to cease resuscitation efforts, minimizing the negative impact of a failed CPCR, and to gain confidence in dealing with the feelings of the owners when discussing CPCR and DNAR.
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Bryfalk, Jennifer, and Therése Hvalgren. "Om hjärtat slutar slå : Patienters och anhörigas delaktighet i beslutet om ej-HLR." Thesis, Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-14227.

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Sjuksköterskor har en nära relation till patienter och anhöriga och bör efter bästa förmåga möjliggöra deras delaktighet i vården. Trots att riktlinjer om hjärt-lungräddning (HLR) menar att beslutskompetenta patienter ska vara delaktiga i beslutet om ej-HLR, fungerar det inte alltid så i praktiken. I och med detta kan sjuksköterskor få svårt att hantera situationer som uppstår kring beslutet om ej-HLR. Syftet var att belysa patienters respektive anhörigas delaktighet i beslutet om ej-HLR. Studien genomfördes som en litteraturstudie och 15 vetenskapliga artiklar analyserades. Studiens resultat visar att patienters och anhörigas delaktighet i beslutet om ej-HLR påverkas av olika faktorer så som patienters livskvalité, information om sjukdom, prognos och HLR. Anhöriga vill och får ofta möjlighet att delta i ett beslut om ej-HLR. Anhörigas möjlighet till delaktighet beror främst på patienters beslutskompetens och det är läkare som möjliggör patienters och anhörigas delaktighet i beslutet om ej-HLR. Sjuksköterskors samarbete med läkare i diskussionen om ej-HLR kan underlätta beslutsprocessen för samtliga parter. För att patienters och anhörigas delaktighet ska främjas bör riktlinjerna för beslut angående HLR ses över och möjligen uppdateras.
The nurse has a close relationship with patients and families and should promote the potential of their involvement in care. The medical practice differs from guidelines for cardiopulmonary resuscitation (CPR) which suggests that patients should be involved in the decision making about the do-not-resuscitate (DNR) order. Nurses may find it difficult to deal with situations that arise over the decision about DNR. The aim was to illuminate patients' and relatives' participation in the decision making concerning the DNR order. The study was conducted as a literature study and 15 scientific articles were analyzed. The results show that involvement of patient and next-of-kin in the decision not to resuscitate can be affected by various factors. Factors that could affect patient participation were patients’ quality of life, knowledge about disease, prognosis and CPR. Family members often want and often get the opportunity to participate in the decision making concerning DNR. Relatives' ability to participate depends primarily on patients' ability to participate in the decision making. Doctors enable patients and families participation in the decision not for resuscitation. Nurses’ collaboration with doctors in the discussion about the DNR order can facilitate decision making for all parties. The guidelines for decision about CPR should be reviewed and possibly updated in order to improve patients' and relatives' participation.
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Hoffman, Denise. "Factors related to differences in nurses' attitudes towards aggressiveness of care for patients with a "do not resuscitate" order a research report submitted ... Acute, Critical and Long Term Care Programs ... Master of Science /." 1993. http://books.google.com/books?id=skZtAAAAMAAJ.

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Ziebart, Jolene Anna. "Negotiating a code status a comparison of elderly persons' and health care providers' perspectives /." 1990. http://catalog.hathitrust.org/api/volumes/oclc/22617188.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 1990.
Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 157-161).
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Ingleton, C., S. Payne, Anita R. Sargeant, and J. Seymour. "Barriers to achieving care at home at the end of life: transferring patients between care settings using patient transport services." 2009. http://hdl.handle.net/10454/6872.

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Enabling patients to be cared for in their preferred location often involves journeys between care settings. The challenge of ensuring journeys are timely and safe emerged as an important issue in an evaluation of palliative care services, which informed a service redesign programme in three areas of the United Kingdom by the Marie Curie Cancer Care 'Delivering Choice Programme'. This article explores perceptions of service users and key stakeholders of palliative care services about problems encountered in journeys between care settings during end-of-life care. This article draws on data from interviews with stakeholders (n = 44), patients (n = 16), carers (n = 19) and bereaved carers (n = 20); and focus groups (n = 9) with specialist nurses. Data were gathered in three areas of the United Kingdom. Data were analysed using a framework approach. Transport problems between care settings emerged as a key theme. Four particular problems were identified: (1) urgent need for transport due to patients' rapidly changing condition; (2) limited time to organise transfers; (3) the management of specialist equipment and (4) the need to clarify the resuscitation status of patients. Partnership working between Ambulance Services and secondary care is required to develop joint protocols of care to ensure timely and safe transportation between care settings of patients, who are near their end of life. Commissioning of services should be responsive to the complexities of patients' needs and those of their families.
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Books on the topic "Resuscitation Orders"

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United States. Veterans Administration. Office of the Medical Inspector., ed. Self-assessment instruments in informed consent, do not resuscitate (DNR) orders, and cardiopulmonary resuscitation. Washington, DC: Veterans Administration, Office of the Medical Inspector, 1994.

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United States. Veterans Administration. Office of the Medical Inspector, ed. Self-assessment instruments in informed consent, do not resuscitate (DNR) orders, and cardiopulmonary resuscitation. Washington, DC: Veterans Administration, Office of the Medical Inspector, 1994.

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United States. Veterans Administration. Office of the Medical Inspector, ed. Self-assessment instruments in informed consent, do not resuscitate (DNR) orders, and cardiopulmonary resuscitation. Washington, DC: Veterans Administration, Office of the Medical Inspector, 1994.

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United States. Veterans Administration. Office of the Medical Inspector., ed. Self-assessment instruments in informed consent, do not resuscitate (DNR) orders, and cardiopulmonary resuscitation. Washington, DC: Veterans Administration, Office of the Medical Inspector, 1994.

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Molloy, William. Let me decide: The health care directive that speaks for you when you can't. 4th ed. Wayzata, Minn: Woodland, 1994.

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Affairs, American Medical Association Council on Ethical and Judicial. Reports on end-of-life care. Chicago, IL: American Medical Association, 1998.

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Let me decide. Troy, Ont: Newgrange, 2000.

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Molloy, William. Let me decide: The health care and personal directive that speaks for you when you can't... 3rd ed. London: Penguin, 1996.

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Molloy, William. Let me decide: The health care directive that speaks for you when you can't. Harmondsworth: Penguin, 1993.

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Dunn, Hank. Hard choices for loving people: CPR, artificial feeding, comfort measures only, and the elderly patient. 3rd ed. Herndon, VA: A & A Pub.,Inc., 1993.

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Book chapters on the topic "Resuscitation Orders"

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ten Have, Henk, and Maria do Céu Patrão Neves. "Resuscitation (including DNR Orders)." In Dictionary of Global Bioethics, 927–28. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-54161-3_457.

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Price, Susanna. "Do-Not-Attempt-Resuscitation Orders in the Cardiac Intensive Care Unit." In Palliative Care in Cardiac Intensive Care Units, 139–46. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-80112-0_9.

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Flabouris, Arthas, and Jack Chen. "The Impact of Rapid Response Systems on Not-For-Resuscitation (NFR) Orders." In Textbook of Rapid Response Systems, 375–82. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-39391-9_36.

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Quill, Timothy E., and Nancy M. Bennett. "The Effects of a Hospital Policy and State Legislation on Resuscitation Orders for Geriatric Patients." In Philosophy and Medicine, 241–50. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-015-8593-4_18.

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Santonocito, Cristina, Filippo Sanfilippo, Giuseppe Ristagno, and Antonino Gullo. "Resuscitation and Ethics: How to Deal with the “Do not Resuscitate Order”?" In Resuscitation, 229–34. Milano: Springer Milan, 2013. http://dx.doi.org/10.1007/978-88-470-5507-0_22.

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De Latorre, F. J. "Do Not Attempt Resuscitation Order." In Intensive and Critical Care Medicine, 35–43. Milano: Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0350-4_5.

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Hess, Andreas. "Maintaining the Equilibrium of Freedom and Order: Talcott Parsons’ Resuscitation of Functionalism." In Concepts of Social Stratification, 112–23. London: Palgrave Macmillan UK, 2001. http://dx.doi.org/10.1057/9780230629219_11.

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Nicholls, Anthony. "Resuscitation decisions." In Perioperative Medicine, 37–40. Oxford University PressOxford, 2006. http://dx.doi.org/10.1093/oso/9780199211739.003.0010.

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Abstract Although patients undergoing elective surgery should automatically receive cardiopulmonary resuscitation (CPR) in the event of cardiac arrest, there are patients in hospital for whom resuscitation would be futile and inappropriate. All hospitals should have policies in place about withholding CPR from these patients, so called ‘do not resuscitate’ or DNR orders. Doubts about the appropriateness of CPR may arise when a patient has major life-threatening complications, when a patient is extremely elderly or frail, when malignancy is the cause of admission, or when the underlying quality of life is poor. CPR in these circumstances may be wrong for the patient, offensive to relatives, and upsetting to medical and nursing staff. An explicit decision about CPR must be made in these patients and recorded in the notes. Relatives should be reassured that in the event of cardiac arrest the patient will be left undisturbed and in dignity.
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Biggs, Hazel. "DNAR: To Resuscitate or Not to Resuscitate?" In Law and ethics in intensive care, edited by Christopher Danbury, Christopher Newdick, Alex Ruck Keene, and Carl Waldmann, 45–66. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198817161.003.0003.

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‘Do not attempt resuscitation (DNAR)’ or ‘do not attempt cardiopulmonary resuscitation (DNACPR)’ orders have been regarded as the best way to ensure that patients are not resuscitated in clinically inappropriate circumstances, or against their wishes. However, the use of DNAR orders has become contentious in situations where individuals have not been informed or consulted before an order has been made, and recent legal cases have highlighted the need for good communication and record keeping. This chapter considers the legal and ethical issues associated with DNAR and DNACPR orders, including the rights of patients, ethical guidance and policies associated with their use, and regional and national variations in practices surrounding their use and implementation. After discussing evidence of misinterpretation and misunderstandings of the implications of such orders in clinical practice, which have an impact on patients’ autonomy and well-being, the chapter will conclude that compliance with ethical and professional guidance must be consistent and mandatory, and suggest the introduction of legal sanctions for non-compliance.
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Siddiqui, Shahla. "Ethics." In Advanced Anesthesia Review, edited by Alaa Abd-Elsayed, 914—C367.S4. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197584521.003.0366.

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Abstract Advance directives preserve patient autonomy and preferences. A do not resuscitate (DNR) order is placed in a patient’s chart after discussing at length their wishes regarding futility and comfort care in the event of the need for resuscitation. If the patient is unable to participate in the discussion, a healthcare proxy or surrogate is asked regarding their perceived wishes. Such discussions occur prior to the need for such resuscitation. In the case of a patient requiring surgery, usually, such DNR orders are voided for the length of the perioperative period. This is because administering anesthesia may trigger instability in a critically ill or palliative patient who may require such resuscitation. A living will defines treatment by establishing parameters under which patients want to be treated. A durable power of attorney for healthcare establishes a surrogate for patients if they are unable to make decisions for themselves.
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Conference papers on the topic "Resuscitation Orders"

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Murphy, Stephen, Kristian Brooks, and Fatima Khalil. "Do not attempt resuscitation (DNAR) orders in patients admitted to hospital with COVID-19." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.oa4288.

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Sullivan, Imogen, and Tim Jackson. "57 Unified do not attempt resuscitation (udnacpr) orders – an audit of communication between different healthcare settings." In The APM’s Annual Supportive and Palliative Care Conference, In association with the Palliative Care Congress, “Towards evidence based compassionate care”, Bournemouth International Centre, 15–16 March 2018. British Medical Journal Publishing Group, 2018. http://dx.doi.org/10.1136/bmjspcare-2018-aspabstracts.84.

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Phelan, Victoria, Louise Tomkow, and Louise Butler. "P-25 Remote decision-making and communication around do not attempt cardio-pulmonary resuscitation (DNACPR) orders in care homes during COVID-19." In Accepted Oral and Poster Abstract Submissions, The Palliative Care Congress, Recovering, Rebounding, Reinventing, 24–25 March 2022, The Telford International Centre, Telford, Shropshire. British Medical Journal Publishing Group, 2022. http://dx.doi.org/10.1136/spcare-2022-scpsc.46.

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Bighamian, Ramin, Andrew T. Reisner, and Jin-Oh Hahn. "A Control-Oriented Model of Blood Volume Response to Hemorrhage and Fluid Resuscitation." In ASME 2015 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/dscc2015-9847.

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This paper presents a control-oriented model of blood volume response to hemorrhage and fluid resuscitation that can be potentially utilized in closed-loop control of fluid resuscitation. A unique characteristic of the proposed model is that it is built to ensure structural parsimony while retaining physiological transparency. To accomplish this characteristic, blood volume regulation in the body to external perturbations of hemorrhage and fluid resuscitation was modeled as a low-order control system in which the fluid transfer between blood and interstitial fluid is governed by a proportional-integral controller. This in essence resulted in a minimal model with four parameters to be adapted to each individual. The validity of the proposed model was tested using data available in the literature. The results indicated that the proposed model was able to reproduce the blood volume response to hemorrhage and fluid resuscitation with high fidelity: on the average, the prediction error was only 1.53 ± 11.5 %, thus strongly supporting our claim that it can be used as viable basis for the design of closed-loop fluid resuscitation controllers.
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Gandhi, Manan, Yunpeng Pan, Evangelos Theodorou, Pierre Sebastian, Matt Olson, and Demetri Yannopoulos. "Learning to Predict Coronary Perfusion Pressure During Cardiopulmonary Resuscitation." In ASME 2018 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dscc2018-8968.

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The goal of this work is to advance the capability of automated, mechanical cardiopulmonary resuscitation (CPR) by predicting Coronary Perfusion Pressure (CPP) within 5 mmHg at a given moment in time. We aim to utilize methods from machine learning in order to model the CPP of a porcine patient subjected to automated chest compressions. During preprocessing of the data, we show how data sampling rate, delays and moving average filtering can improve predictions. We demonstrate state of the art modeling performance utilizing a variety of algorithms, and analyze the performance of each algorithm for single-step and long-term predictions. The results indicate that a delayed linear system achieves this target CPP within 0.25 mmHg. For longer time horizons, a more complex model is required. We demonstrate that the Long-short-term-memory (LSTM) network has the best single run performance, while the Sparse Spectrum Gaussian Process (SSGP) has the best average performance.
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Bolyukh, Vladimir F., Igor I. Katkov, Vsevolod Katkov, and Ilya Yakhnenko. "KrioBlastTM: A Hyper-Fast Cooling and Thawing Scalable Device for Vitrification of Stem and Other Cells in Large Volumes." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-85468.

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Abstract:
Kinetic (very rapid) vitrification (KVF) is a very promising approach in cryopreservation (CP) of biological materials as it is simple, avoids lethal intracellular ice formation (IIF) and minimizes damaging dehydration effects of extracellular crystallization. Moreover, achieving the ultra-high rates, which would prevent IIF during cooling and devitrification during resuscitation, and achieve KVF for practically any type of cells with one protocol of cooling and re-warming would be the “Holy Grail” of cell cryobiology [3]. However such hyperrapid rates currently require very small sample size which, however, is insufficient for many applications such as stem cells, blood or sperm. As the result, even smallest droplets of 0.25 microliters cannot be vitrified sufficiently fast to avoid the use of potentially toxic external vitrification agents such as DMSO or EG due to the Leidenfrost effect (LFE). In this presentation, we describe an entirely new system for hyperfast cooling of one-two order of magnitude larger samples that we call “KrioBlastTM”, which completely eliminates LFE. We have successfully vitrified up to 4,000 microliters of 15% glycerol solutions, which theoretically corresponds to the critical cooling rate of hundreds of thousands °C/min. We believe that such a system can revolutionize the future cryobiological paradigm.
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