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Journal articles on the topic 'Retroorbital pain'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Demir, Berat, Ghazi Abuzaid, Zeynep Ergenc, and Eda Kepenekli. "Delayed diagnosed Gradenigo’s syndrome associated with acute otitis media." SAGE Open Medical Case Reports 8 (January 2020): 2050313X2096611. http://dx.doi.org/10.1177/2050313x20966119.

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Gradenigo’s syndrome presents as a triad of retroorbital pain, ipsilateral abducens palsy, and purulent otorrhea. If the otologic pathologies in Gradenigo’s syndrome go unnoticed, the condition could be misdiagnosed with neurological diseases because of retroorbital pain and abducens palsy. Treatment of Gradenigo’s syndrome remains controversial. Although some reports state that long-term antibiotic treatment is sufficient, we recommended that management ought to be guided on a case-by-case basis depending on patient and disease factors. Herein, we report a delayed diagnosed pediatric case of

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Arustamyan, I. G., S. A. Karpischenko, O. A. Stancheva, et al. "Retrobulbar pain in isolated sphenoiditis." Meditsinskiy sovet = Medical Council, no. 7 (May 24, 2025): 150–55. https://doi.org/10.21518/ms2025-048.

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Introduction. The opacification of the unilateral sphenoidal sinus (USS) in computed tomography is caused by various diseases, including inflammation and infectious sinusitis, benign and malignant tumors and encephalocles. Symptoms of isolated lesions of this sinus are varied and nonspecific. This symptom includes retrobulbar pain, which does not occur with other paranasal spasms. This makes this symptom diagnostically valuable.Aim. Тo consider the relationship between the presence of retrobulbar pain in patients with isolated sphenoiditis and the nature of pathological changes in the sinus.Ma

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3

Foerderreuther, S., R. v. Maydell, and A. Straube. "A CPH-Like Picture in Two Patients with an Orbitocavernous Sinus Syndrome." Cephalalgia 17, no. 5 (1997): 608–11. http://dx.doi.org/10.1046/j.1468-2982.1997.1705608.x.

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Two patients with retroorbital pain syndromes with or without paresis of cranial nerves developed weeks after ipsilateral headache resembling chronic paroxysmal hemicrania (CPH) but without autonomic features. These findings might support the hypothesis that CPH may be caused by a pathological process in the region of the cavernous sinus, as has been proposed for the Tolosa-Hunt syndrome (THS).

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Viana, Pedro F., Harumoto Hasegawa, Josef Jarosz, Ata Siddiqui, Richard P. Selway, and Nandini Mullatti. "Short-lasting retroorbital pain attacks as a form of ictal epileptic headache: Case report." Cephalalgia 39, no. 9 (2019): 1195–99. http://dx.doi.org/10.1177/0333102419839792.

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Background and objectives Ictal epileptic headache is a rare form of painful seizure, habitually consisting of migrainous or tension-type headache. We describe a case of a patient with short-lasting, severe retroorbital pain attacks caused by frontal lobe epilepsy. Case report A 25-year-old male patient presented with recurrent attacks of paroxysmal, short-lasting, excruciating left periorbital and facial pain mainly occurring from sleep. After intracranial EEG exploration and resection of a right prefrontal focal cortical dysplasia, long-term seizure and headache remission was obtained. Discu

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Elashaal, AA, and Y. Elashaal. "P.138 Sphenoidal Sinus aspergillus infection presenting with right-sided painful ophthalmoplegia and cavernous sinus-orbital apex lesion: a case report." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 50, s2 (2023): S93—S94. http://dx.doi.org/10.1017/cjn.2023.226.

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Background: Cavernous sinus-orbital apex aspergillosis is a rare but serious complication and difficult to diagnose based on clinical and radiological results. This condition is frequently diagnosed at a late stage because of its nonspecific and varying symptomatology, specifically in immuno-supressive patients. Early diagnosis and treatment is the key to prevent more serious central nerves system complications. Methods: We report the case of a 80-year-old man with a 2 month history of retroorbital pain before he developed a subacute cavernous sinus syndrome, with 3th cranial nerve palsy and r

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Peddi, Prakash, Kevin M. Gallagher, Chandrikha Chandrasekharan, et al. "Tolosa-Hunt Syndrome in Double-Hit Lymphoma." Case Reports in Oncological Medicine 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/249891.

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Tolosa-Hunt syndrome (THS) is a painful condition characterized by hemicranial pain, retroorbital pain, loss of vision, oculomotor nerve paralysis, and sensory loss in distribution of ophthalmic and maxillary division of trigeminal nerve. Lymphomas rarely involve cavernous sinus and simulate Tolosa-Hunt syndrome. Here we present a first case of double-hit B cell lymphoma (DHL) relapsing and masquerading as Tolosa-Hunt syndrome. The neurological findings were explained by a lymphomatous infiltration of the right Gasserian ganglion which preceded systemic relapse. As part of this report, the dia

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Bansal, Priyanshu, Vineet Sehgal, Lucky Bhalla, and Shaifali Arora. "Covid-19 induced optic neuritis – A case report." IP Indian Journal of Neurosciences 7, no. 4 (2022): 337–40. http://dx.doi.org/10.18231/j.ijn.2021.062.

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COVID-19 illness is an evolving disorder, and many extrapulmonary manifestations have been reported. With this report, we are highlighting one of the neuro-ophthalmologic complications of Covid-19. We report a case of 16 years old boy who presented with complaints of rapid loss of vision and retroorbital pain in the Right eye during recovery from Covid -19 infection. Clinically, radiologically, CSF, Blood, and all other investigations suggest Probable Covid -19 Right Eye Optic Neuritis. The patient showed remarkable recovery following steroid therapy. This report aims to add a case to the limi

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Maksimova, M. Yu, S. N. Illarioshkin, and I. A. Savizkaya. "Reccurent painful ophthalmoplegic neuropathy." Russian neurological journal 27, no. 6 (2023): 77–83. http://dx.doi.org/10.30629/2658-7947-2022-27-6-77-83.

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Reccurent painful ophthalmoplegic neuropathy (the Tolosa–Hunt syndrome) occurs due to a nonspecific granulomatous infl ammation of the walls of the cavernous sinus and the intracavernous segment of the internal carotid artery. It consists of one or more oculomotor nerves dysfunction associated with peri- and retroorbital pain; spontaneous remissions and relapses are typical. Oculomotor nerve disorders may coincide with the onset of pain or follow it within a period of up to 2 weeks. Demonstration of granulomatosis in the walls of the cavernous sinus and the intracavernous segment of the intern

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Vipassana V.Khandait, Vipassana V. Khandait, Sucheta S. Pawar Sucheta S. Pawar, Shreya A. Kirdat Shreya A.Kirdat, Akshata R. Sathe Akshata R. Sathe, and Pratiksha S. Khamkar Pratiksha S. Khamkar. "Unmasking Dengue: A Holistic Review of Virus Classification, Pathophysiology, Diagnosis & Herbal Remedies." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1829–33. https://doi.org/10.35629/4494-100218291833.

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The virus that causes dengue, known as the dengue virus(DENV),is a member of the Flavivirus genus and is spread by mosquitoes. The mosquitoes Aedesaegypti and Aedesalbopictus are the main vectors of transmission. With an estimated 390 million infections each year worldwide, the disease is common in tropical and subtropical climates. From mild feverish disease (dengue fever) to serious complications like dengue hemorrhagic fever (DHF) and potentially fatal dengue shock syndrome (DSS), dengue can appear with a broad range of clinical symptoms. Skin rashes, retroorbital pain, joint and muscle pai

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10

Higashida, Randall T., V. Van Halbach, Grant B. Hieshima, and Leslie Cahan. "Cavernous Carotid Artery Aneurysm Associated with Marfan's Syndrome: Treatment by Balloon Embolization Therapy." Neurosurgery 22, no. 2 (1988): 297–300. http://dx.doi.org/10.1227/00006123-198802000-00003.

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Abstract Intracranial aneurysms arising in the region of the cavernous carotid artery are difficult to manage surgically because of the surrounding cavernous sinus. With recent advances in microballoon technology and permanent solidification agents, it is now possible to treat certain intracranial aneurysms by detachable balloons and preserve the parent vessel. A patient with Marfan's syndrome presented with severe retroorbital pain, ophthalmoplegia, and headaches. Cerebral angiography demonstrated a large cavernous carotid artery aneurysm measuring 17 × 9 × 6 mm. This was successfully treated

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Delpassand, Ebrahim S., and Joel B. Kirkpatrick. "Cavernous Sinus Syndrome as the Presentation of Malignant Lymphoma: Case Report and Review of the Literature." Neurosurgery 23, no. 4 (1988): 501–4. http://dx.doi.org/10.1227/00006123-198810000-00018.

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Abstract Cavernous sinus syndrome (CSS) is an unusual presentation of malignant lymphoma. We report a patient with lymphoma that presented with CSS, and we review the literature on nine other reported cases. Sharp retroorbital pain, paresthesia around the orbit, and complete 6th nerve palsy were dominant presenting symptoms. In all cases, the tumor developed on the right side. The computed tomographic scan was abnormal in only two of the nine patients during the early stages of the disease. The dominant histological type was large cell lymphoma. The mean age of the patients was 45 years. The m

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Rodgers, Shaun D., Bryan J. Marascalchi, Russell G. Strom, and Paul P. Huang. "Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome secondary to an epidermoid tumor in the cerebellopontine angle." Neurosurgical Focus 34, no. 3 (2013): E1. http://dx.doi.org/10.3171/2013.1.focus12233.

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Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome is classified under trigeminal autonomic cephalalgias. This rare headache syndrome is infrequently associated with secondary pathologies. In this paper the authors report on a patient with paroxysmal left retroorbital pain with associated autonomic symptoms of ipsilateral conjunctival injection and lacrimation, suggestive of SUNCT syndrome. After failed medical treatment an MRI sequence was obtained in this patient, demonstrating an epidermoid tumor in the left cerebellopontine angle

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Narra, Rama Krishna, Buridi Praneetha, and Rajendra Kumar Pamidi. "Periorbital emphysema in mechanical air blast injury." BMJ Case Reports 18, no. 5 (2025): e264467. https://doi.org/10.1136/bcr-2024-264467.

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A young adult male presented to the emergency department, due to an accidental compressed air injury by high-pressurised air hoses, complaining of left-sided facial pain, swelling and an inability to open his left eye. The left eye appeared oedematous on clinical examination, with swelling extending to the premaxillary region. Additional findings included conjunctival chemosis, palpable crepitus and tears in the inferotemporal bulbar conjunctiva accompanied by subconjunctival haemorrhage. CT of the brain, orbits and facial bones revealed periorbital emphysema around the left orbit, with air po

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Panda, Prateek Kumar, and Srikant Kumar Padhy. "Orbital compression syndrome: a rare complication of sickle cell disease in children." International Journal of Contemporary Pediatrics 6, no. 2 (2019): 890. http://dx.doi.org/10.18203/2349-3291.ijcp20190750.

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Vasoocclusive crises in sickle cell disease commonly involve bone marrow of the long bones and vertebrae. Involvement of bones with less marrow space, including the bones of the orbit, is reported rarely in the literature. The present case is a 6-year-old boy, a known case of sickle cell disease, who presented with acute onset right upper and lower eyelid swelling, restriction of extraocular movement and pain. USG orbit showed a retroorbital hemorrhage compressing on the orbit, probably due to orbital bone infarction. The child was managed successfully with red blood cell transfusion and intra

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15

Mangudkar, Sangram S., Sachin K. Shivnitwar, and Atiullah I. Malik. "Study of clinical and laboratory profile of dengue fever in a tertiary care hospital." International Journal of Advances in Medicine 7, no. 2 (2020): 222. http://dx.doi.org/10.18203/2349-3933.ijam20200042.

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Background: Dengue fever is one of the most common arboviral mediated outbreaks reported with increased prevalence over the last few years with considerable morbidity and mortality. This study was designed to study the clinical and biochemical parameters in dengue fever patients.Methods: Prospective observational study was undertaken among adult patients in a tertiary care hospital. fifty patients were studied and analysed. All patients who were NS1 (Non-Structural Protein 1) antigen or IgM dengue positive were included in the study. Clinical features, haematological and biochemical parameters

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Siritho, Sasitorn, Wadchara Pumpradit, Wiboon Suriyajakryuththana, and Krit Pongpirul. "Severe Headache with Eye Involvement from Herpes Zoster Ophthalmicus, Trigeminal Tract, and Brainstem Nuclei." Case Reports in Radiology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/402015.

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A 43-year-old female presented with severe sharp stabbing right-sided periorbital and retroorbital area headache, dull-aching unilateral jaw pain, eyelid swelling, ptosis, and tearing of the right eye but no rash. The pain episodes lasted five minutes to one hour and occurred 10–15 times per day with unremitting milder pain between the attacks. She later developed an erythematous maculopapular rash over the right forehead and therefore was treated with antivirals. MRI performed one month after the onset revealed small hypersignal-T2 in the right dorsolateral mid-pons and from the right dorsola

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Zhang, H., Y. P. Zhou, H. J. Peng, et al. "Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever: A Meta-Analysis." BioMed Research International 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/359308.

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The aim of the meta-analysis was to provide more solid evidence for the reliability of the new classification. A systematic literature search was performed using PubMed, Armed Forces Pest Management Board Literature Retrieval System, and Google Scholar up to August 2012. A pooled odds ratio (OR) was calculated using either a random-effect or a fixed-effect model. A total of 16 papers were identified. Among the 11 factors studied, five symptoms demonstrated an increased risk for SDD, including bleeding [OR: 13.617; 95% confidence interval (CI): 3.281, 56.508], vomiting/nausea (OR: 1.692; 95% CI

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Dr., Muhammad Wasim Khan Muhammad Mujahid Muhammad Haris Qureshi. "ACUTE DENGUE FEVER INFECTION VARIATION IN DIFFERENT REGIONS OF MULTAN DIVISON ADMITTED AT TERTIARY CARE HOSPITAL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 3661–64. https://doi.org/10.5281/zenodo.1245725.

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<strong><em>Objective:</em></strong><em> To evaluate the clinical manifestations and regional variations of acute dengue infection among patients. </em> <strong><em>Study Design:</em></strong><em> A descriptive study </em> <strong><em>Place and Duration:</em></strong><em> The study was conducted between August 1, 2010 and March 30, 2011 at the Microbiology Department of the Nishter Medical University, Multan. </em> <strong><em>Methodology:</em></strong><em>  For all suspected acute dengue patients admitted in dengue ward simple random sampling technique was used. ELISA test used to detect

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Morita, Akio, Fredric B. Meyer, and Edward R. Laws. "Symptomatic pituitary metastases." Journal of Neurosurgery 89, no. 1 (1998): 69–73. http://dx.doi.org/10.3171/jns.1998.89.1.0069.

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Object. The diagnosis and treatment of metastasis to the pituitary gland can be difficult to determine. The goal of this study was to analyze the clinical presentation, treatment, and prognosis of patients who presented with symptomatic pituitary metastasis. Methods. The cases of 36 patients with symptomatic pituitary metastases were reviewed. The most common primary cancers were breast (33%) and lung (36%). The presenting symptoms included diabetes insipidus, anterior pituitary insufficiency, and retroorbital pain. The overall median length of patient survival following diagnosis of pituitary

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Medeiros, Frederico Carvalho de, Lucas Alverne Freitas de Albuquerque, Jose Eymard Homem Pittella, Renata Brant de Souza, Antonio Pereira Gomes Neto, and Paulo Pereira Christo. "Open-Ring Enhancement in Pseudotumoral Multiple Sclerosis: Important Radiological Aspect." Case Reports in Neurological Medicine 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/951690.

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Introduction. Observation of open-ring enhancement in magnetic resonance imaging (MRI) is considered a specificity marker for diagnosing pseudotumoral multiple sclerosis (MS). This finding is of great value in the differential diagnosis of tumefactive lesions.Case Report. We describe a 55-year-old white woman, with previous history of ovarian cancer and recent history of fatigue and bilateral retroorbital pain. Important bilateral visual impairment evolved over one month. Physical examination detected the presence of right homonymous hemianopia. Cranial MRI showed an expanding lesion with open

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Altay, Tamer, Khaled M. Krisht, and William T. Couldwell. "Sellar and Parasellar Metastatic Tumors." International Journal of Surgical Oncology 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/647256.

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The sellar and parasellar (SPS) region is a complex area rich in vital neurovascular structures and as such may be the location of first manifestation of a systemic malignancy. Metastases to this region are rare; breast cancer is the most common source among those that metastasize to the SPS region. Ophthalmoplegia, headache, retroorbital or facial pain, diabetes insipidus, and visual field defects are the most commonly reported symptoms. Lack of specific clinical and radiological features renders SPS metastases difficult to differentiate from the other frequently encountered lesions in this a

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Check, J. H., G. DiAntonio, and R. Cohen. "Dextroamphetamine sulfate, a very effective drug for pelvic pain relieved severe retroorbital stabbing pain in a woman with keratoconus who failed to respond to bilateral corneal implants." Clinical and Experimental Obstetrics & Gynecology 41, no. 1 (2014): 80–82. http://dx.doi.org/10.12891/ceog16912014.

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Chikkaveeraiah, Shashidhara Kuppegala, K. M. Srinath, Basavanagowdappa V. Hathur, V. S. Aravindh Hari, and Lakshman Sai Vanama. "Study of Dengue Fever in an Epidemic - A Single Centre Observational Study at Tertiary Care Hospital." APIK Journal of Internal Medicine 12, no. 4 (2024): 205–9. http://dx.doi.org/10.4103/ajim.ajim_45_23.

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Introduction: Dengue fever (DF) is one of the most common and the most important vector-borne diseases caused by arboviruses with a significant mortality and morbidity. The incidence of DF is increasing over the years. This study aims to map the clinical features of the disease. Materials and Methods: This prospective, observational study was done among adult patients at a tertiary care medical college hospital. Two thousand three hundred and fourteen patients were studied and analyzed. All patients who were nonstructural protein 1 (NS1) antigen/IgM dengue positive were included in the study.

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de Souza, Thiara, Edcelha Ribeiro, Valmir Corrêa, et al. "Following in the Footsteps of the Chikungunya Virus in Brazil: The First Autochthonous Cases in Amapá in 2014 and Its Emergence in Rio de Janeiro during 2016." Viruses 10, no. 11 (2018): 623. http://dx.doi.org/10.3390/v10110623.

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Currently, Brazil lives a triple arboviruses epidemic (DENV, ZIKV and CHIKV) making the differential diagnosis difficult for health professionals. Here, we aimed to investigate chikungunya cases and the possible occurrence of co-infections during the epidemic in Amapá (AP) that started in 2014 when the first autochthonous cases were reported and in Rio de Janeiro (RJ) in 2016. We further performed molecular characterization and genotyping of representative strains. In AP, 51.4% of the suspected cases were confirmed for CHIKV, 71.0% (76/107). Of those, 24 co-infections by CHIKV/DENV, two by CHI

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Nirav, Parmar, Solanki Hiral, Bajaniya Ramesh, and Dangi Ashwin. "A Study of Clinical Profile of Dengue Fever in Children at a Tertiary Care Centre in Kalol Town of Gandhinagar District in Gujarat, India." International Journal of Pharmaceutical and Clinical Research 15, no. 12 (2023): 759–63. https://doi.org/10.5281/zenodo.11193323.

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<strong>Background and Aim:</strong> Dengue fever remains a significant public health concern, particularly in tropical regions. This prospective observational study aimed to comprehensively analyze the clinical manifestations, laboratory findings, and outcomes of dengue fever cases in a specified geographic area. <strong>Material and Methods: </strong>The study was conducted at the Department of Pediatrics, Ananya College of Medicine and Research, Kalol, Gandhinagar, India, from September 2022 to August 2023. A total of 53 cases were enrolled, with demographic distribution refl

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Alawadhi, A., C. Saint-Martin, and M. Oskoui. "P.025 Magnetic resonance imaging in pediatric recurrent ophthalmoplegic cranial neuropathy." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 44, S2 (2017): S19—S20. http://dx.doi.org/10.1017/cjn.2017.110.

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Background: Recurrent ophthalmoplegic cranial neuropathy (ROCN), previously called ophthalmoplegic migraine, is characterized by recurrent episodes of headache and ophthalmoplegia of unclear etiology. Characteristic neuroimaging findings can support the diagnosis. Methods: A case report and review of the literature. Results: We present a 6-year-old girl with a past history of migraine headaches associated with retroorbital pain since 4 years of age. Family history is positive for migraine. She presented with a half a day history of left eye ptosis, 10 days post a resolved gastroenteritis which

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Selvan, Tamil, Nagaraj M. V., Saravanan P., and Somashekar. "A study of clinical profile of dengue fever in children." International Journal of Contemporary Pediatrics 4, no. 2 (2017): 534. http://dx.doi.org/10.18203/2349-3291.ijcp20170704.

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Background: Dengue is a major international health concern and is a major health problem in India which constantly threatens the health care system. The objective of the present study was to study the clinical profile of dengue fever in children.Methods: Prospective and descriptive study was conducted on all the laboratory confirmed cases of dengue fever in children admitted at SIMS and RC over a period of 1 year from December 2015 to November 2016. Results: Among 568 children studied, majority of them were males 63.3% and in the age group of 10-18 years 39.4%. The most common symptoms noticed

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Muhammad, Shajil p. t., Kailas N. Chintale, and Meenakshi A. Bhattacharya. "Study of Clinical Profile of Dengue Fever in Tertiary Care Hospital." International Journal of Pharmaceutical and Clinical Research 14, no. 12 (2022): 366–71. https://doi.org/10.5281/zenodo.13212221.

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<strong>Background:</strong> Dengue fever is a most common arboviral disease in India. Dengue viruses are spread to people through the bite of an infected Aedes species (Ae.aegypti or Ae.albopticus). Dengue has a varied and wide spectrum of clinical presentations. Objectives of this study were to evaluate the clinical profile of dengue fever and to study Outcome and clinical predictor of mortality in dengue patients. <strong>Methods:</strong> This was a cross sectional, descriptive observational study done in tertiary care hospital and teaching institute, study period was from D

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Setjaputra, Vina Lidya, Steven Christian Susianto, and Abdulloh Machin, MD, PhD, Neurologist. "Headache Characteristic in Covid-19 Infected Patient: A Systematic Review." Asian Journal of Health Research 2, no. 2 (2023): 77–86. http://dx.doi.org/10.55561/ajhr.v2i2.113.

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Introduction: The neurotropism of COVID-19 virus has been addressed in several studies, and headache is one of the most frequent neurologic manifestations of COVID-19, with various results of characteristics and phenotype. In this systematic review, we aimed to characterize the most common phenotype of headache in COVID-19 infected patients. Methods: A systematic literature was conducted through Pubmed, SciElo and Cochrane databases with keywords (headache[Title]) AND (covid-19[Title]), ((neurological) AND (headache) AND (characteristic)) AND (covid-19), ((phenotype) AND (headache)) AND (covid

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Aksun, M. S., T. K. Sahin, E. C. Bolek, et al. "AB1038 INFLAMMATORY ORBITAL DISEASES: THE EXPERIENCE OF A TERTIARY RHEUMATOLOGY CENTRE." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1810–11. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6446.

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Background:Inflammatory lesions of orbital disease encompass a wide spectrum of clinical entities including rheumatic disorders.Objectives:To describe our experiences in adult patients who applied to a tertiary rheumatology center due to orbital disease.Methods:This is a retrospective descriptive study and data were extracted from patient’ charts. We described the clinical, laboratory, radiologic, histopathological presentations and final diagnoses of patients with inflammatory orbital disease who applied to our rheumatology clinic between January 2014 and December 2019.Results:Thirty-eight pa

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Wahiduzzaman, Miah, Arifin Islam Lita, Raian Md Hassan, et al. "Exploring variations in dengue symptoms: a comparative study of 2013, 2019, and 2023 in a tertiary care hospital of Bangladesh." BIRDEM Medical Journal 14, no. 3 (2024): 131–36. http://dx.doi.org/10.3329/birdem.v14i3.76237.

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Background: Dengue fever remains a major public health issue in Bangladesh, with repeated outbreaks. This study compares dengue symptoms in a tertiary care hospital during 2013, 2019, and 2023. The purpose of this study is to evaluate the variations in dengue symptoms among Bangladeshi dengue patients from 2013 and 2019 to 2023. Methods: This was a cross-sectional study, conducted on 100 dengue positive patients, admitted between 1st January to 7th August 2023, to the Medicine Department, Holy Family Red Crescent Medical College and Hospital, Dhaka. Demographic data, sign and symptoms and labo

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Pangemanan, Damajanty Hellen Carol, Joice Nancy Ansje Engka, and Euis Farncoise Setiawaty Pangemanan. "Anti-Inflammatory Activity Assay Using the Human Red Blood Cell Membrane Stabilization Method for Pasote Leaf Extract (Dysphania ambrosioides L.)." Scholars Journal of Applied Medical Sciences 13, no. 01 (2025): 77–82. https://doi.org/10.36347/sjams.2025.v13i01.013.

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Dysphania ambrosioides L., or pasote leaves, is a herbal plant widely used in traditional medicine in various parts of the world, including in Indonesia. This plant is known to have multiple properties, especially in overcoming health problems related to inflammation. Inflammation is a complex biological response to injury or infection. Therefore, searching for compounds that can reduce inflammation is very important in developing new therapies. A useful technique for assessing a compound's anti-inflammatory properties is the red blood cell membrane stabilization method. This technique measure

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Santiago, Marc Reinald G., and Natividad A. Almazan. "Gradenigo Syndrome." Philippine Journal of Otolaryngology-Head and Neck Surgery 23, no. 2 (2008): 46–48. http://dx.doi.org/10.32412/pjohns.v23i2.747.

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Chronic suppurative otitis media (CSOM) has a potential for intratemporal complications. Gradenigo syndrome, lateral sinus thrombosis and cavernous sinus thrombosis must be considered when patients present with ear discharge, headache, fever and lateral rectus palsy. Computed Tomography and Magnetic Resonance Imaging are essential in confirming the diagnosis but do not substitute for a good clinical eye in establishing the diagnosis and initiating proper treatment. CASE A 17 year old male with an 11-year history of otorrhea on the right ear was admitted because of on-and-off diffus

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Liu, James K., Yuan Lu, Ahmed M. Raslan, S. Humayun Gultekin, and Johnny B. Delashaw. "Cavernous malformations of the optic pathway and hypothalamus: analysis of 65 cases in the literature." Neurosurgical Focus 29, no. 3 (2010): E17. http://dx.doi.org/10.3171/2010.5.focus10129.

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Object Cavernous malformations (CMs) of the optic pathway and hypothalamus (OPH) are extremely rare. Patients with these lesions typically present with chiasmal apoplexy, characterized by sudden visual loss, acute headaches, retroorbital pain, and nausea. Surgical removal is the recommended treatment to restore or preserve vision and to eliminate the risk of future hemorrhage. However, the anatomical location and eloquence of nearby neural structures can make these lesions difficult to access and remove. In this study, the authors review the literature for reported cases of OPH CMs to analyze

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Raman, Md Habibur, Abu Yousuf Md Shahidul Alam, AKM Mijanur Rahman, Md Sarwar Khan, Nahid Reaz Shapla, and Mohammad Abdul Aleem. "Presentation, Management and Outcome of Dengue Fever A Study of 200 Cases." Journal of Medicine 14, no. 1 (2013): 18–22. http://dx.doi.org/10.3329/jom.v14i1.14531.

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Background: Dengue is the most rapidly spreading mosquito-borne viral disease in the world1. The rapidly expanding global footprint of dengue is a public health challenge. The endemicity of dengue is also increasing in Bangladesh. This study highlights our current understanding of dengue, including its clinical manifestations, laboratory tests, management and outcome. Objectives: This study was designed to document the presenting features and outcome of Dengue infection in Border Guard personnel. Materials and Methods: It was a prospective observational study which was carried out among outpat

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Simpson, Victoria J., Brad A. Rikke, Jennifer M. Costello, Robin Corley, and Thomas E. Johnson. "Identification of a Genetic Region in Mice that Specifies Sensitivity to Propofol." Anesthesiology 88, no. 2 (1998): 379–89. http://dx.doi.org/10.1097/00000542-199802000-00017.

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Background Long-sleep (LS) and short-sleep (SS) mice, initially selected for differential sensitivity to ethanol, also exhibit differential sensitivity to propofol. By interbreeding LS and SS mice to obtain progeny whose chromosomes are a patchwork of the LS and SS chromosomes, the authors determined whether differential propofol sensitivity cosegregates with any particular chromosomal region(s). Such cosegregation is the essence of genetic linkage mapping and a first step toward isolating a gene that can modulate propofol sensitivity in mammals. A gene underlying a quantitative trait such as

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Yamaguchi, Toshimasa, Rie Oyama, and Katsushu Shimizu. "Unilateral Retroorbital Pain Secondary to Isolated Sphenoid Sinus Aspergillosis." Sultan Qaboos University Medical Journal, December 21, 2022. http://dx.doi.org/10.18295/squmj.12.2022.063.

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Jo, Eun Jung, Eunjin Bae, Jeong-Hwan Yoon, Ji Yeon Kim, and Jin Soo Han. "Comparison of murine retroorbital plexus and facial vein blood collection to mitigate animal ethics issues." Laboratory Animal Research 37, no. 1 (2021). http://dx.doi.org/10.1186/s42826-021-00090-4.

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Abstract Background Blood collection is an important procedure used in animal experiments. Blood collection methods that reduce pain, injury, and stress in experimental animals are important with regard to animal ethics. Various comparative studies of blood collection methods have been reported; however, there are no comparative studies on serial blood collection considering animal ethics. To suggest simple methods that minimize pain during serial blood collection, we compared the retroorbital plexus (RP) and facial vein (FV) blood collection methods performed by both experienced and novice gr

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Balasubramanian, Thiagarajan. "Patterns of orbital disorders." Otoloaryngology Online, August 18, 2014. https://doi.org/10.5281/zenodo.812516.

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This article discusses various patterns of presentations of orbital lesions. Since this article has been authored by an otolaryngologist, the entire concept has been viewed from otolaryngologist's angle. With the advent of nasal endoscope trans nasal access to orbit is becoming the order of the day. Major advantage being that external skin incision is avoided. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down.

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Meena, Poonam, Satish Meena, Ashok Meena, and Kailash Meena. "THE CLINICAL PROFILE OF DENGUE PATIENTS IN CHILDREN." International Journal of Medical and Biomedical Studies 5, no. 12 (2021). http://dx.doi.org/10.32553/ijmbs.v5i12.2328.

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Background: To study the clinical profile of dengue in children Methods: The hospital based study was conducted on patients presenting to paediatric hospital, who fulfilled inclusion and exclusion criteria. Results: Based on the symptoms, the most common symptoms noticed were fever 94.00% followed by myalgia 85.00% decreased appetite 83%, retroorbital pain in 84.0% and vomiting 81.00% Conclusion: It concluded that common symptoms observed were fever, myalgia, decreased appetite and headache The common complications presented were hepatic dysfunction and shock with no mortalit

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Fraiman, Pedro, André Lopes Valente, Maria Eduarda Slhsessarenko Fraife Barreto, et al. "Sarcoid optic neuropathy." Practical Neurology, November 6, 2023, pn—2023–003939. http://dx.doi.org/10.1136/pn-2023-003939.

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A 45-year-old woman presented with sudden complete vision loss in her left eye and retroorbital pain worsened by eye movements. A previous milder episode of vision loss had occurred in the same eye 1 year before, with complete recovery after high-dose intravenous methylprednisolone. She had no light perception in the left eye with a swollen optic disc, but with a normal right optic disc. There were no systemic manifestations or infections. MR scan of the brain showed extensive enlargement and enhancement of the left optic nerve and optic chiasm. After excluding infections and autoimmune marker

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Yılmaz, Ebru, Nilgün Güldoğan, Aydan Arslan, and Ceyda Civan. "Pleomorphic Invasive Lobular Cancer of the Breast Presenting with Orbital Metastasis: A Case Report." Current Medical Imaging Formerly: Current Medical Imaging Reviews 17 (September 16, 2021). http://dx.doi.org/10.2174/1573405617666210916115321.

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Background: Orbital metastasis of breast cancer is an unusual condition, especially in the absence of a previous diagnosis of primary breast cancer. The main MRI findings in patients with orbital metastasis are retroorbital soft tissue with thickening of extraocular muscles. Paradoxical enophtalmos secondary to fibrosis can be seen. Case Report: In this case report we present a 75-year-old female patient with left eye pain and blurred vision and retraction. Although there was no evidence of malignancy in the biopsy of the orbita; since the patient's complaints continued despite idiopathic pseu

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Isaac, Heba, Andrew Liu, Seiji B. Shibata, and Marlan R. Hansen. "Transmastoid and Transtemporal Drainage of Petrous Apicitis with Otitis Media." Annals of Otology, Rhinology & Laryngology, August 8, 2020, 000348942094959. http://dx.doi.org/10.1177/0003489420949591.

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Background: Petrous apicitis (PA) is a serious infection involving the apical portion of the petrous temporal bone. The classic triad of purulent otorrhea, ipsilateral abducens nerve palsy and retroorbital pain is rarely seen due to early detection and widespread use of antibiotics. Medical management is the primary treatment modality with surgery reserved for cases of recalcitrant petrous apex abscess. Methods and Results: We presented a case of PA with previously untreated otitis media. After multidisciplinary evaluation, the patient was initially treated with intravenous antibiotics followe

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Rizwan Aziz Qazi and Hina Siddiqui. "Chronic Dengue Syndrome: A Narrative Review." Journal of Islamabad Medical & Dental College 13, no. 1 (2024). http://dx.doi.org/10.35787/jimdc.v13i1.1184.

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Dengue fever (DF) is a dynamic disease. As the disease progresses, the course of treatment changes. Symptoms range from mild (e.g., fever, headache, retroorbital pain, nausea, vomiting, rash, myalgia, arthralgia) to severe body pain (e.g., rash fever), severe (e.g., dengue hemorrhagic fever) (DHF) and dengue shock syndrome. It changes. (DSS). DHF and DSS are associated with poor outcomes. Although there is a classification of dengue into DF, DHF, and DSS, overlap has been observed between the different presentations. In dengue, end organ damage such as liver, kidney, heart, brain, and bone mar

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Neelagiri, Udaya Kumar. "A clinical study of early manifestations of dengue fever and outcome in children." PERSPECTIVES IN MEDICAL RESEARCH, November 16, 2020, 15–19. http://dx.doi.org/10.47799/pimr.0802.06.

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Background: In the past few decades the incidence, distribution, and clinical severity of Dengue have increased dramatically. Population growth in the tropics provides many susceptible hosts. Uncontrolled urbanization leads to inadequate management of water and waste, providing a range of large water stores and disposable, non-biodegradable containers that become habitats for the larvae. Children are now being increasingly affected by this disease. We in this present study tried to study clinical, hematological, and hepatic dysfunction in the early course of the disease. Methods: The present p

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Hossain, Md Jubayer, Manisha Das, Muhibullah Shahjahan, Md Wahidul Islam, and Syeda Tasneem Towhid. "Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study." Health Science Reports 8, no. 1 (2025). https://doi.org/10.1002/hsr2.70356.

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ABSTRACTBackground and AimsDengue is a mosquito‐borne viral disease that frequently causes seasonal outbreaks in Bangladesh, particularly during the monsoon months from June to September. Recent outbreaks have shown significant shifts in clinical manifestations, including changes in the timeframe and serotype mixing. This study focused on the clinical and hematological profiles of patients during the 2022 outbreak, which was notably severe.MethodsThis quantitative cross‐sectional study at Dhaka Medical College and Hospital classified 67 dengue‐positive patients as having dengue fever (DF), den

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DO, Michael Gaspari, Behnam Rabiee, Muhamad Festok MD, and Imtiaz Chaudhry. "Central Retinal Vein Occlusion following Poppers Use in a Healthy Young Male." Journal of Clinical and Medical Images, Case Reports 2, no. 3 (2022). http://dx.doi.org/10.55920/2771-019x/1160.

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The patient is a 33-year-old male with no past ocular or medical history who presented to the office with several days of left retroorbital pain and headache but no vision changes or vision loss. Ocular examination revealed visual acuity in both eyes without correction of 20/20. Pupils were equal, and no afferent pupillary defect was noted. External ocular motility was intact, and no visual field defects were demonstrated on confrontational field testing. Color testing was normal with an 8/8 score on the Ishihara test. Intraocular pressure was 14 OD and 16 OS. Slit-lamp examination demonstrate

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Martín, Marta, Ana Isabel Pérez, and Álvaro Pineda. "A case of progressive exophthalmos in a 5-year-old girl." Revista Pediatría Atención Primaria 26, no. 103 (2024). http://dx.doi.org/10.60147/695146e2.

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Introduction: spindle cell sarcoma is a rare tumor, with little presentation in the literature. Soft tissue tumors constitute a heterogeneous group, requiring a multidisciplinary approach. Clinical case: 5-year-old schoolboy who goes to his pediatrician for exophthalmos. His mother refers a progressive proptosis in the left eye of 6 months of evolution. No loss of visual acuity, in the last weeks intermittent pain with eye movements. On examination proptosis of the left eye with intermittent tearing and vascular lesion in the temporal portion of the same eye, he presented restriction of left e

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Bolognese, Paolo, Michael Caton, Ilene Ruhoy, et al. "A Case Report on Symptomatic Internal Jugular Venous Compression: Clinical and Radiographic Improvement with Bilateral C1 Tubercle Resection." Medical Research Archives 12, no. 5 (2024). http://dx.doi.org/10.18103/mra.v12i4.5415.

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This case report examines internal jugular venous compression necessitating surgical intervention. The focal point is a 48-year-old female patient with Ehlers-Danlos syndrome, who developed intracranial hypertension due to bilateral compression of the internal jugular veins. The patient's symptomatic presentation, marked by persistent pain and pressure localized to retroorbital and occipital regions, accentuated during orthostatic conditions, propelled the investigation that culminated in a comprehensive evaluation via cranial and cervical computed tomography. The diagnostic revelation of bila

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Bolognese, Paolo, Michael Caton, Ilene Ruhoy, et al. "A Case Report on Symptomatic Internal Jugular Venous Compression: Clinical and Radiographic Improvement with Bilateral C1 Tubercle Resection." Medical Research Archives 12, no. 5 (2024). http://dx.doi.org/10.18103/mra.v12i5.5415.

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This case report examines internal jugular venous compression necessitating surgical intervention. The focal point is a 48-year-old female patient with Ehlers-Danlos syndrome, who developed intracranial hypertension due to bilateral compression of the internal jugular veins. The patient's symptomatic presentation, marked by persistent pain and pressure localized to retroorbital and occipital regions, accentuated during orthostatic conditions, propelled the investigation that culminated in a comprehensive evaluation via cranial and cervical computed tomography. The diagnostic revelation of bila

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