Academic literature on the topic 'Reverse γ-turn'

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Journal articles on the topic "Reverse γ-turn"

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Belvisi, Laura, Cesare Gennari, Antonia Mielgo, Donatella Potenza та Carlo Scolastico. "Conformational Preferences of Peptides Containing Reverse-Turn Mimetic Bicyclic Lactams: Inverse γ-Turns versus Type-II′ β-Turns – Insights into β-Hairpin Stability". European Journal of Organic Chemistry 1999, № 2 (1999): 389–400. http://dx.doi.org/10.1002/(sici)1099-0690(199902)1999:2<389::aid-ejoc389>3.0.co;2-7.

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Belvisi, Laura, Cesare Gennari, Antonia Mielgo, Donatella Potenza та Carlo Scolastico. "ChemInform Abstract: Conformational Preferences of Peptides Containing Reverse-Turn Mimetic Bicyclic Lactams: Inverse γ-Turns versus Type-II′ β-Turns - Insights into β-Hairpin Stability." ChemInform 30, № 23 (2010): no. http://dx.doi.org/10.1002/chin.199923219.

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Legrand, Baptiste, Loïc Mathieu, Aurélien Lebrun та ін. "Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation". Chemistry - A European Journal 20, № 22 (2014): 6713–20. http://dx.doi.org/10.1002/chem.201402190.

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Hanessian, Stephen, Xuehong Luo та Robert Schaum. "Synthesis and folding preferences of γ-amino acid oligopeptides: stereochemical control in the formation of a reverse turn and a helix". Tetrahedron Letters 40, № 27 (1999): 4925–29. http://dx.doi.org/10.1016/s0040-4039(99)00860-6.

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Jones, Christopher R, M. Khurram N Qureshi, Fiona R Truscott, Shang-Te Danny Hsu, Angus J Morrison та Martin D Smith. "A Nonpeptidic Reverse Turn that Promotes Parallel Sheet Structure Stabilized by CH⋅⋅⋅O Hydrogen Bonds in a Cyclopropane γ-Peptide". Angewandte Chemie 120, № 37 (2008): 7207–10. http://dx.doi.org/10.1002/ange.200802648.

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Jones, Christopher R, M. Khurram N Qureshi, Fiona R Truscott, Shang-Te Danny Hsu, Angus J Morrison та Martin D Smith. "A Nonpeptidic Reverse Turn that Promotes Parallel Sheet Structure Stabilized by CH⋅⋅⋅O Hydrogen Bonds in a Cyclopropane γ-Peptide". Angewandte Chemie International Edition 47, № 37 (2008): 7099–102. http://dx.doi.org/10.1002/anie.200802648.

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Hanessian, Stephen, Xuehong Luo та Robert Schaum. "ChemInform Abstract: Synthesis and Folding Preferences of γ-Amino Acid Oligopeptides: Stereochemical Control in the Formation of a Reverse Turn and a Helix." ChemInform 30, № 35 (2010): no. http://dx.doi.org/10.1002/chin.199935231.

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Rama Iñiguez, S., M. A. Dea-Ayuela, J. A. Sanchez-Brunete, J. J. Torrado, J. M. Alunda, and F. Bolas-Fernández. "Real-Time Reverse Transcription-PCR Quantification of Cytokine mRNA Expression in Golden Syrian Hamster Infected with Leishmania infantum and Treated with a New Amphotericin B Formulation." Antimicrobial Agents and Chemotherapy 50, no. 4 (2006): 1195–201. http://dx.doi.org/10.1128/aac.50.4.1195-1201.2006.

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ABSTRACT A real-time quantitative reverse transcription-PCR assay was developed for the quantification of cytokine mRNA expression in the golden Syrian hamster Mesocricetus auratus infected with Leishmania infantum and treated with amphotericin B (AMB) formulated in microspheres made of human serum albumin (HSA). Treatment was administered intravenously on days 69, 71, and 73 postinfection (p.i.) with 107 metacyclic promastigotes, at doses of 2 and 40 mg/kg of AMB. High infection levels were recorded for untreated animals by day 76 p.i., with parasite loads always about 2 log10 per gram higher
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Shen, Zheng, Xiaomei Liang, Christopher Q. Rogers, Drew Rideout, and Min You. "Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty liver in mice." American Journal of Physiology-Gastrointestinal and Liver Physiology 298, no. 3 (2010): G364—G374. http://dx.doi.org/10.1152/ajpgi.00456.2009.

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The development of alcoholic fatty liver is associated with reduced adipocyte-derived adiponectin levels, decreased hepatic adiponectin receptors, and deranged hepatic adiponectin signaling in animals. Peroxisomal proliferator-activated receptor-γ (PPAR-γ) plays a key role in the regulation of adiponectin in adipose tissue. The aim of the present study was to test the ability of rosiglitazone, a known PPAR-γ agonist, to reverse the inhibitory effects of ethanol on adiponectin expression and its hepatic signaling, and to attenuate alcoholic liver steatosis in mice. Mice were fed modified Lieber
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Torday, J. S., and V. K. Rehan. "The evolutionary continuum from lung development to homeostasis and repair." American Journal of Physiology-Lung Cellular and Molecular Physiology 292, no. 3 (2007): L608—L611. http://dx.doi.org/10.1152/ajplung.00379.2006.

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A functional, developmental, and comparative biological approach is probably the most effective way for arranging gene regulatory networks (GRNs) in their biological contexts. Evolutionary developmental biology allows comparison of GRNs during development across phyla. For lung evolution, the parathyroid hormone-related protein (PTHrP) GRN exemplifies a continuum from ontogeny to phylogeny, homeostasis, and repair. PTHrP signaling between the lung endoderm and mesoderm stimulates lipofibroblast differentiation by downregulating the myofibroblast Wnt signaling pathway and upregulating the prote
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Dissertations / Theses on the topic "Reverse γ-turn"

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Dufour-Gallant, Julien. "Synthèse en phase solide de pyrrolo[3,2-e][1,4]diazépin-2-ones modulateurs du système urotensinergétique." Thèse, 2016. http://hdl.handle.net/1866/18417.

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Les pyrrolodiazépinones ont des activités biologiques intéressantes sur différents récepteurs biologiques, ce qui en font une cible de choix pour développer de nouvelles petites molécules biologiquement actives. Une méthodologie en solution a été développée pour synthétiser des pyrrolo[3,2-e][1,4]diazépin-2-ones, qui utilise la réaction de Pictet-Spengler pour former le cycle diazépinone, comme réaction clé. Il a été démontré que le pyrrolo[3,2-e][1,4]diazépin-2-one mime un tour-γ inverse par l’analyse de cristaux par rayon X. Cette méthodologie a été transposée sur trois types de support, soi
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