Academic literature on the topic 'Reverse zoonoses'

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Journal articles on the topic "Reverse zoonoses"

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Noman, Zakaria, Shadia Tasnim, Rony Masud, et al. "A systematic review on reverse-zoonosis: Global impact and changes in transmission patterns." Journal of Advanced Veterinary and Animal Research 11, no. 3 (2024): 601. http://dx.doi.org/10.5455/javar.2024.k810.

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Reverse zoonosis or zooanthroponosis is the transfer of pathogens from humans to animals. Although less studied than zoonotic diseases, this phenomenon poses significant risks to both animal and public health. The increasing human-animal interactions driven by urbanization, globalization, and environmental changes have exacerbated the occurrence of reverse zoonosis. This review evaluated the global impact and transmission patterns of reverse zoonosis, highlighting the anthropogenic and intrinsic factors contributing to its emergence. The study performed a systematic review and included 91 scientific articles published from 2000 to 2022, covering viral, bacterial, parasitic, fungal, and protozoal reverse zoonoses. This study indicated that viral infections, particularly respiratory viruses such as severe acute respiratory syndrome coronavirus-2 and influenza, have the highest incidence of reverse zoonosis, followed by bacterial infections like tuberculosis and methicillin-resistant Staphylococcus aureus. The United States, India, and Hong Kong are among the most reported regions for reverse zoonotic events. Major risk factors identified include environmental degradation, climate change, antimicrobial resistance, and global wildlife trade. The review underscores the need for enhanced surveillance systems, interdisciplinary collaboration, and stringent regulations on wildlife trade and animal husbandry practices to mitigate the risks associated with reverse zoonosis. Understanding the dynamics of human-animal pathogen transmission is crucial for developing not only effective but also sustainable strategies to protect animal populations as well as public health from emerging infectious diseases.
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Donnik, I. M., I. A. Chvala, L. K. Kish, and A. M. Ermakov. "Coronavirus Infections in Animals: Risks of Direct and Reverse Zoonoses." Herald of the Russian Academy of Sciences 92, no. 4 (2022): 491–96. http://dx.doi.org/10.1134/s1019331622040116.

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Prasad, Minakshi, Mayukh Ghosh, Rajesh Kumar, et al. "The Importance of Nanomedicine in Prophylactic and Theranostic Intervention of Bacterial Zoonoses and Reverse Zoonoses in the Era of Microbial Resistance." Journal of Nanoscience and Nanotechnology 21, no. 6 (2021): 3404–52. http://dx.doi.org/10.1166/jnn.2021.18999.

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Emergence of multidrug resistance (MDR), extensively drug resistance (XDR) and pandrug resistance (PDR) strains of bacteria in communicable diseases of zoonotic and reverse zoonotic importance is the major hurdle of one health concept. Increasing level of resistance against antibiotics among bacterial population throughout the world, slow pace of new antibacterial drug discovery and enhanced pace of resistance development by pathogenic bacteria possess major challenges for human and animal health as well as life in future. Alternative management strategy in terms of improved prophylactic vaccine; early, easy and effective diagnostics and therapeutic drugs against those resistant bacteria is the need of the hour. In this context nanomedicine can fit into the multifaceted demands as an effective prophylactic and theranostic alternative to control the communicable diseases in a cost effective manner in the era of microbial resistance. The current review is focused towards delineating the application of nanomaterials as vaccine or drug delivery system, diagnostics and directly acting antimicrobial therapeutic agents in combating the important zoonotic and reverse zoonotic bacterial diseases in recent scenario along with their potential benefits, limitations and future prospects to formulate successful eradication strategies.
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E., Tamileniyan1 M. Jeevitha1 P.Thrisha2 And M.Veeraselvam3. "Kyasanur Forest Disease – A Re-emerging Tick-borne Viral Zoonoses." Science World a monthly e magazine 2, no. 11 (2022): 1884–88. https://doi.org/10.5281/zenodo.7361597.

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&nbsp;Zoonoses is a disease transmission occur from animals to humans and vice versa.&nbsp; When human infects the animals, it is called reverse zoonosis or anthropozoonosis. One of the re-emerging vectors borne zoonotic disease is Kyasanur Forest Disease (KFD), which is caused by Flavivirus characterized by Fever followed by Neurological complications. KFD was first reported in Kyasanur forest area, Shimoga district of Karnataka. It affects monkeys especially langur and humans. Humans are the dead-end host to this virus. &nbsp;The vector for transmission of KFDV is mainly through ticks especially the nymphs of <em>Haemaphysalis spinigera </em>and<em> Haemaphysalis turturis </em>species. The incubation period is 3-8 days. First stage is haemorrhagic fever and the second stage is meningoencephalitis. Kysanur forest disease can be diagnosed by PCR, ELISA and other molecular techniques. No specific treatment is available for Kyasanur Forest Disease. The target areas are the endemic areas in Karnataka, which should be periodically vaccinated.
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Pattnaik, Bramhadev, Sharanagouda S Patil, Chandrashekar S, et al. "COVID-19 PANDEMIC: A SYSTEMATIC REVIEW ON THE CORONAVIRUSES OF ANIMALS AND SARS-CoV-2." Journal of Experimental Biology and Agricultural Sciences 9, no. 2 (2021): 117–30. http://dx.doi.org/10.18006/2021.9(2).117.130.

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Coronaviruses (CoVs), classified into four genera, viz., alpha-, beta-, gamma-, and Delta- CoV, represent an important group of diverse transboundary pathogens that can infect a variety of mammalian and avian species including humans, animals, poultry, and non-poultry birds. CoVs primarily infect lung and gut epithelial cells, besides monocytes and macrophages. CoVs have high mutation rates causing changes in host specificity, tissue tropism, and mode of virus excretion and transmissions. The recent CoV zoonoses are SARS, MERS, and COVID-19 that are caused by the transmission of beta-CoVs of bats to humans. Recently, reverse zoonoses of the COVID-19 virus have been detected in dogs, tigers, and minks. Beta-CoV strains also infect bovine (BCoV) and canine species (CRCoV); both these beta-CoVs might have originated from a common ancestor. Despite the high genetic similarity between BCoV, CRCoV, and HCoV-OC43, these differ in species specificity. Alpha-CoV strains infect canine (CCoV), feline (FIPV), swine (TGEV and PEDV), and humans (HCoV229E and NL63). Six coronavirus species are known to infect and cause disease in pigs, seven in human beings, and two in dogs. The high mutation rate in CoVs is attributed to error-prone 3′-5′ exoribonuclease (NSP 14), and genetic recombination to template shift by the polymerase. The present compilation describes the important features of the CoVs and diseases caused in humans, animals, and birds that are essential in surveillance of diverse pool of CoVs circulating in nature, and monitoring interspecies transmission, zoonoses, and reverse zoonoses.
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Koeppel, Katja Natalie, Adriano Mendes, Amy Strydom, Lia Rotherham, Misheck Mulumba, and Marietjie Venter. "SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa." Viruses 14, no. 1 (2022): 120. http://dx.doi.org/10.3390/v14010120.

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Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks.
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Messenger, Ali M., Amber N. Barnes, and Gregory C. Gray. "Reverse zoonotic disease transmission (zooanthroponosis): a systematic review of seldom-documented human biological threats to animals." PloS One 9, no. 2 (2014): e89055. https://doi.org/10.5281/zenodo.13505180.

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(Uploaded by Plazi for the Bat Literature Project) BACKGROUND: Research regarding zoonotic diseases often focuses on infectious diseases animals have given to humans. However, an increasing number of reports indicate that humans are transmitting pathogens to animals. Recent examples include methicillin-resistant Staphylococcus aureus, influenza A virus, Cryptosporidium parvum, and Ascaris lumbricoides. The aim of this review was to provide an overview of published literature regarding reverse zoonoses and highlight the need for future work in this area. METHODS: An initial broad literature review yielded 4763 titles, of which 4704 were excluded as not meeting inclusion criteria. After careful screening, 56 articles (from 56 countries over three decades) with documented human-to-animal disease transmission were included in this report. FINDINGS: In these publications, 21 (38%) pathogens studied were bacterial, 16 (29%) were viral, 12 (21%) were parasitic, and 7 (13%) were fungal, other, or involved multiple pathogens. Effected animals included wildlife (n = 28, 50%), livestock (n = 24, 43%), companion animals (n = 13, 23%), and various other animals or animals not explicitly mentioned (n = 2, 4%). Published reports of reverse zoonoses transmission occurred in every continent except Antarctica therefore indicating a worldwide disease threat. INTERPRETATION: As we see a global increase in industrial animal production, the rapid movement of humans and animals, and the habitats of humans and wild animals intertwining with great complexity, the future promises more opportunities for humans to cause reverse zoonoses. Scientific research must be conducted in this area to provide a richer understanding of emerging and reemerging disease threats. As a result, multidisciplinary approaches such as One Health will be needed to mitigate these problems.
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Messenger, Ali M., Amber N. Barnes, and Gregory C. Gray. "Reverse zoonotic disease transmission (zooanthroponosis): a systematic review of seldom-documented human biological threats to animals." PloS One 9, no. 2 (2014): e89055. https://doi.org/10.5281/zenodo.13505180.

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(Uploaded by Plazi for the Bat Literature Project) BACKGROUND: Research regarding zoonotic diseases often focuses on infectious diseases animals have given to humans. However, an increasing number of reports indicate that humans are transmitting pathogens to animals. Recent examples include methicillin-resistant Staphylococcus aureus, influenza A virus, Cryptosporidium parvum, and Ascaris lumbricoides. The aim of this review was to provide an overview of published literature regarding reverse zoonoses and highlight the need for future work in this area. METHODS: An initial broad literature review yielded 4763 titles, of which 4704 were excluded as not meeting inclusion criteria. After careful screening, 56 articles (from 56 countries over three decades) with documented human-to-animal disease transmission were included in this report. FINDINGS: In these publications, 21 (38%) pathogens studied were bacterial, 16 (29%) were viral, 12 (21%) were parasitic, and 7 (13%) were fungal, other, or involved multiple pathogens. Effected animals included wildlife (n = 28, 50%), livestock (n = 24, 43%), companion animals (n = 13, 23%), and various other animals or animals not explicitly mentioned (n = 2, 4%). Published reports of reverse zoonoses transmission occurred in every continent except Antarctica therefore indicating a worldwide disease threat. INTERPRETATION: As we see a global increase in industrial animal production, the rapid movement of humans and animals, and the habitats of humans and wild animals intertwining with great complexity, the future promises more opportunities for humans to cause reverse zoonoses. Scientific research must be conducted in this area to provide a richer understanding of emerging and reemerging disease threats. As a result, multidisciplinary approaches such as One Health will be needed to mitigate these problems.
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Perin, Patricia Parreira, Talita Turmina, Carmen Andrea Arias-Pacheco, et al. "Rabies Virus-Neutralizing Antibodies in Free-Ranging Invasive Wild Boars (Sus scrofa) from Brazil." Pathogens 13, no. 4 (2024): 303. http://dx.doi.org/10.3390/pathogens13040303.

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Rabies, one of the most lethal global zoonoses, affects all mammals. It remains circulating worldwide in sylvatic cycles through terrestrial and airborne reservoirs, and in Brazil, bats are currently the main reservoirs and source of transmission. Wild boars, an important invasive alien species in Brazil, are a proven food source for hematophagous bats and may participate in the Brazilian sylvatic cycle of rabies. We evaluated the presence of this pathogen in hunted wild boars from the São Paulo state using histopathology, the direct fluorescent antibody test (DFA), viral isolation in cell culture (VICC), the rapid fluorescent focus inhibition test (RFFIT), and quantitative reverse transcription polymerase chain reaction (RT-qPCR). The results of histopathological, DFA, VICC, and RT-qPCR analysis were negative for all samples; seven serum samples tested positive in the RFFIT, and titers ranged from 0.13 IU/mL to 0.5 IU/mL. The presence of rabies virus-neutralizing antibodies in the studied wild boars suggests the circulation of the virus in these animals. Educative actions directed at hunters should include information on the prevention of this important zoonosis.
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صمدی, اسدالله. "زونوز‌های معکوس: تغییر مسیر انتقال بیماری‌های مشترک بین انسان‌ها و". Journal of Natural Sciences – Kabul University 5, № 2 (2025): 11–22. https://doi.org/10.62810/jns.v5i2.270.

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تمرکز اکثر تحقیقات علمی بالای نقش حیوانات در بقا و انتقال عوامل بیماری‌های زونوز به انسان بوده است، اما اخیراً گزارشات زیادی پیرامون نقش انسان‌ها در بقا و انتشار عوامل بیماری‌زای زونوز به حیوانات به نشر رسیده اند. هم‌چو بیماری‌های زونوز به‌حیث زونوزهای معکوس (reverse zoonoses) شناخته شده و به‌نام zooanthroponoses (انتقال بیماری از انسان به حیوان) یاد می‌شوند. با وجودی‌که انسان‌ها عوامل مختلف زونوز را به حیوانات فارم، حیوانات همراه (companion animals) و جهان وحش انتقال می‌دهند، اما ویروس‌های عامل COVID-19 و انفلوانزا، عوامل توبرکلوز و سترن‌های مقاوم به میتیسیلین ستافیلوکوکوس اوریوس (methicillin resistance Staphylococcus aureus “MRSA”) بیشتر از همه با اهمیت بوده و تهدیدات باالقوه را برای جمعیت‌های حیوانی و در نتیجه جمعیت‌های حساس انسانی به‌وجود آورده اند. زیرا، در اکثر حالات حیوانات مبتلاشده به‌حیث منبع عفونت عمل نموده و عوامل بیماری‌زا را دوباره به انسان‌ها و سایر حیوانات انتقال نموده اند.
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Dissertations / Theses on the topic "Reverse zoonoses"

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Seixas, Neto Amilton. "Novas abordagens para o desenvolvimento de uma vacina contra a leptospirose." Universidade Federal de Pelotas, 2014. http://repositorio.ufpel.edu.br:8080/handle/prefix/3707.

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Submitted by Maria Beatriz Vieira (mbeatriz.vieira@gmail.com) on 2017-08-30T12:11:02Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) tese_amilton_seixas_neto.pdf: 1214618 bytes, checksum: 70b8eeecc3cf0dfb3f4b6426f0b70ca4 (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-09-01T19:11:22Z (GMT) No. of bitstreams: 2 tese_amilton_seixas_neto.pdf: 1214618 bytes, checksum: 70b8eeecc3cf0dfb3f4b6426f0b70ca4 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-09-01T19:12:10Z (GMT) No. of bitstreams: 2 tese_amilton_seixas_neto.pdf: 1214618 bytes, checksum: 70b8eeecc3cf0dfb3f4b6426f0b70ca4 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Made available in DSpace on 2017-09-01T19:12:20Z (GMT). No. of bitstreams: 2 tese_amilton_seixas_neto.pdf: 1214618 bytes, checksum: 70b8eeecc3cf0dfb3f4b6426f0b70ca4 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2014-08-06<br>Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul - FAPERGS<br>A leptospirose é uma zoonose que possui distribuição mundial, causando um importante impacto econômico no setor agropecuário. Atualmente, as vacinas empregadas para a prevenção da enfermidade são formuladas com culturas de leptospiras inteiras inativadas, as quais possuem sucesso limitado, já que induzem uma imunidade de curta duração e proteção sorovar-específica. Resultados preliminares revelaram que fragmentos recombinantes das proteínas Ligs (Leptospiral immunoglobulin-like) são antigênicas, imunogênicas e conferem proteção total ou parcial contra o desafio homólogo em hamsters. Dessa forma, fragmentos rLigs são candidatos potenciais para uma vacina de subunidade contra a leptospirose humana e animal. Assim sendo, a proposta deste projeto foi avaliar preparações vacinais com as proteínas recombinantes LigA625-1224aa (rLigANI), LigB131-649aa (rLigBRep), LigB625-1044aa (rLigB7-11) e LigA131-1224aa (rLigAFull) quando administradas com Hidróxido de Alumínio como adjuvante, individualmente ou combinadas, a fim de identificar quais formulações serão capazes de induzir uma resposta protetora contra o desafio homólogo. Hamsters machos e fêmeas foram imunizados com as preparações através da via intramuscular, nos dias 0 e 14, e o desafio homólogo foi realizado através da via intraperitoneal, no dia 28, utilizando Leptospira interrogans sorovar Copenhageni cepa Fiocruz L1-130. Após a expressão e purificação das quatro proteínas, obteve-se quatro lotes com pureza de 90%. Todas as quatro proteínas recombinantes apresentaram antigenicidade, reagindo contra soro de humanos e animal convalescentes de leptospirose. A imunização dos hamsters contendo as preparações com rLigANI, rLigBRep, rLigB7-11 e rLigAFull conferiram proteções variáveis (0-100%) contra o desafio homólogo. Embora nenhuma preparação tenha induzido a uma proteção esterilizante, evidenciada através das técnicas de reisolamento e imunofluorescência, a associação entre rLigANI e rLigBRep foi capaz de conferir proteção significativa (p<0,05) em todos os experimentos. Em contrapartida, o fragmento inteiro de LigA, assim como rLigB7-11, não conferiram proteção. Nosso estudo propôs uma nova abordagem para o desenvolvimento de uma vacina recombinante contra a leptospirose. É o primeiro estudo que testou a proteína LigA recombinante em sua forma inteira. Além disso, foi possível obter a sua expressão na forma solúvel. Embora a proteína obtida tenha sido reconhecida por soros de humanos convalescentes in vitro, foi capaz de conferir apenas níveis de sobrevivência significativa (p<0,05) aos animais desafiados, mas não em relação à mortalidade. Por outro lado, a associação entre rLigBRep e rLigANI, outra abordagem inédita, demonstrou que mesmo testando-se em diferentes doses (40g ou 60g) de cada alvo, tanto a análise de mortalidade quanto a de sobrevivência revelou resultados significativos (p<0,01) em três dos cinco experimentos realizados. Os resultados obtidos em nosso estudo representam uma contribuição importante para o desenvolvimento de uma vacina contra a leptospirose.<br>Leptospirosis is a worldwide zoonosis, causing a major economic impact on the agricultural sector. Currently, the vaccines used to prevent disease in cattle are formulated with inactivated Leptospira whole-cell bacterins, which have limited success, since they induce an immunity of short duration and serovar-specific protection. Preliminary results from our group showed that recombinant fragments of Lig (leptospiral immunoglobulin-like) proteins are antigenic, immunogenic and confer full or partial protection against homologous challenge in hamster model. Thus, rLigs fragments are potential candidates for a subunit vaccine against human and animal leptospirosis. Therefore, the purpose of this study was to evaluate vaccine preparations with recombinant proteins LigA625-1224aa (rLigANI), LigB131-649aa (rLigBRep), LigB625-1044aa (rLigB7-11) and LigA131-1224aa (rLigAFull) when administered with Alum Hydroxide as adjuvant, either individually or combined, in order to identify formulations that are capable of inducing a protective response against homologous challenge. Male and female hamsters were immunized with the preparations by intramuscular injection on days 0 and 14, and the homologous challenge was performed using Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130, by intraperitoneal injection on day 28. Following expression and purification of the four proteins were obtained four batches with a purity of 90%. All four recombinant proteins showed antigenicity, reacting against human sera with convalescent leptospirosis. Immunization of hamsters with preparations containing rLigANI, rLigBRep, rLigB7-11, and rLigAFull conferred variable protection (0-100%) against homologous challenge. Although no preparation has induced a sterilizing protection, evidenced by the isolation and immunofluorescence techniques, the association between rLigANI and rLigBRep was able to confer significant protection (p <0.05) in all experiments. In contrast, the LigAFull as well as rLigB7-11, did not provide protection. Our study has proposed a new approach for the development of a recombinant vaccine against bovine leptospirosis. It is the first study that tested the rLigA in its entire form. Furthermore, it was possible to obtain expression in soluble form. Although the protein obtained has been recognized by sera from convalescent human in vitro, it was only capable of conferring significant levels of survival (p <0.05) to challenged animals but not in relation to mortality. Moreover, the association between rLigBRep and rLigANI, another novel approach, testing showed that even at different doses (40 g ou 60 g) of each target, both the analysis of the mortality and survival showed significant results (p <0.01) in three of the five experiments. The results obtained in our study represent an important contribution to the development of a vaccine against leptospirosis.
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Books on the topic "Reverse zoonoses"

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Dawson, Susan. Other bacterial diseasesStaphylococcal zoonoses. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0026.

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Staphylococcal species are common commensals of the skin and mucous membranes of humans and animals but only in very recent years has zoonotic infections been recognised. They can also be associated with infection and disease, especially coagulase positive organisms. Staphylococcus aureus is relatively frequently carried by humans in the nasal passages and is a cause of infections in people including bacteraemias in hospitalised patients. More recently some strains of Staphylococcus aureus have acquired a resistance gene (mecA) which renders them resistant to meticillin (meticillin-resistant Staphylococcus aureus, MRSA). MRSA isolates are of major importance in healthcare situations as well as increasingly in the community. Animals can also be carriers of Staphylococcus aureus although less frequently than humans and MRSA can be carried or infect several different host species. For companion animals such as dogs and cats, the most frequently isolated MRSA strains are similar to the common local human healthcare strains; thus for the UK, EMRSA-15 and -16. This suggests a reverse zoonosis with spill over from the human population into their companion animals. In horses the situation is different, with some horses carrying or infected with human epidemic strains but others infected with strains less frequently seen in people. For food-producing animals the picture is different again with a particular strain, ST398, which appears to circulate endemically in animal populations, such as pigs, and can spill over into the human population where it can cause carriage as well as infection and disease. The transmission appears to be by direct contact with animals rather than through the food-chain.Where risk factors for infection with MRSA have been studied in animals they appear similar to some of the risks for human infection. Therefore, for control of MRSA in animals measures such as improved hygiene and good antibacterial stewardship are important.
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Clement, Jan, and Piet Maes. Hantaviral infections. Edited by Vivekanand Jha. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0188_update_001.

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Hantavirus disease is a viral zoonosis, caused by inhalation of infectious aerosolized excreta from chronically infected rodents, which are both the reservoir and the vector of different hantavirus species. Hantavirus infections manifest mainly as haemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome, which traditionally but incorrectly were thought to be caused by exclusively Old World hantaviruses and New World hantaviruses, respectively.Hantavirus diseases are characterized by non-specific flu-like symptoms, followed by a sometimes lethal capillary leak syndrome, haemorrhage, and rarely by shock. Infection is accompanied by augmented release of pro-inflammatory cytokines which indirectly causes organ damage. Diagnosis can be made by serology or plaque reduction neutralization tests, detection of viral proteins by Western blot assay, or detection of hantavirus genome by reverse transcription-polymerase chain reaction. Treatment is mainly supportive.Together with leptospirosis, haemorrhagic fever with renal syndrome is the only form of acute kidney injury against which vaccines are in use, but a World Health Organization-licensed vaccine is still lacking.
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Book chapters on the topic "Reverse zoonoses"

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Anderson, Benjamin D., Amber N. Barnes, Sajid Umar, Xinrong Guo, Thanaporn Thongthum, and Gregory C. Gray. "Reverse Zoonotic Transmission (Zooanthroponosis): An Increasing Threat to Animal Health." In Zoonoses: Infections Affecting Humans and Animals. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-030-85877-3_59-1.

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Anderson, Benjamin D., Amber N. Barnes, Sajid Umar, Xinrong Guo, Thanaporn Thongthum, and Gregory C. Gray. "Reverse Zoonotic Transmission (Zooanthroponosis): An Increasing Threat to Animal Health." In Zoonoses: Infections Affecting Humans and Animals. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-27164-9_59.

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Capria, Anna, Indresh Singh, Christian Zmasek, Elliot J. Lefkowitz, and Richard Scheuermann. "BV-BRC Zoonosis or Reverse Zoonosis Example." In Methods in Molecular Biology. Springer US, 2025. https://doi.org/10.1007/978-1-0716-4546-8_8.

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Sing, Andreas, and Anja Berger. "Cats – Revered and Reviled – and Associated Zoonoses." In Zoonoses: Infections Affecting Humans and Animals. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-27164-9_23.

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Sing, Andreas, and Anja Berger. "Cats – Revered and Reviled – and Associated Zoonoses." In Zoonoses: Infections Affecting Humans and Animals. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85877-3_23-1.

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Galán-Puchades, M. Teresa. "Guinea Worm Infection in Dogs: A Case of Reverse Zoonosis that Impedes Dracunculus medinensis Eradication." In Parasitology Research Monographs. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53230-7_12.

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Nandi, Jayashree Seema. "Zoonoses and anthroponoses: Reverse transmission of pathogens." In Global Perspectives on the Transmission of Zoonotic RNA Viruses from Wild Animal Species to Humans. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-443-13267-4.00010-7.

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A. Saied, AbdulRahman, Faten F. Mohammed, and Asmaa A. Metwally. "SARS-CoV-2 Secondary Spillover: From Doubt to Evidence." In Current Topics in Zoonoses [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.114129.

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Abstract:
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the culprit behind the coronavirus disease 2019 (COVID-19) and it is believed that bats may have been the source. SARS-CoV-2 can naturally infect humans and various animal species, including pets, farm animals, zoo animals, and wild animals that might serve as potential reservoirs for the viral transmission to humans. Most infected animals with SARS-CoV-2 are associated with exposure to infected humans; therefore, SARS-CoV-2 is characterized by zoonosis and reverse zoonosis. It is critical to quickly detect and classify variants of concern of SARS-CoV-2 in both domestic and wild animals. In addition, it’s possible that novel variants emerging due to viral mutation, making the infection of incidental animal hosts worrying. Here, we discuss the most recent information on the spreading of SARS-CoV-2 among animals and humans, the importance of genomic research, and active surveillance of these animals that may help us to understand the spread of viruses and the emergence of variants.
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9

Bhogilal Nayak, Jitendrakumar, Jeetendrakumar Harnathbhai Chaudhary, Prakrutik Prafulchandra Bhavsar, Pranav Ashok Anjaria, Manojbhai N. Brahmbhatt, and Urvish Pravinbhai Mistry. "Rabies: Incurable Biological Threat." In Zoonoses of Public Health Interest [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.105079.

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Rabies is a lethal zoonotic disease that affects all the homeotherms, including humans, and is caused by the Rabies virus of Rhabdoviridae family. Every year, this disease kills about 55,000 individuals globally. The stray dog is a key player in the spread of rabies. The disease is usually transmitted through the bite of a rabid animal. After being exposed to the virus, the virus must travel to the brain before generating symptoms. Delirium, unusual behaviour, hallucinations, hydrophobia and insomnia may occur as the condition advances. Diagnostic tests such as direct fluorescent antibody test (dFAT), direct rapid immunohistochemical test (dRIT), lateral flow assay (LFA), reverse transcriptase polymerase chain reaction (RT-PCR), nuclear sequencing, etc. are used in diagnosis of this dreadful disease. The genotype and lineage of the rabies virus can be determined via N gene sequencing and phylogenetic analysis. There is no effective treatment for rabies. Even though a tiny number of people have survived rabies, the disease is usually fatal. Rabies can be completely avoided in people if they receive timely and adequate medical treatment. Vaccinating and sterilising the dogs in our neighbourhoods effectively and humanely limit their population and eliminate rabies in both dogs and humans.
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Uhl, Elizabeth W., and Richard Thomas. "Uncovering tales of transmission: an integrated palaeopathological perspective on the evolution of shared human and animal pathogens." In Palaeopathology and Evolutionary Medicine. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198849711.003.0017.

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This chapter highlights the potential of an integrated palaeopathological approach for unravelling the evolutionary history of shared human and animal pathogens. The transfer of pathogens between animals and humans has occurred for millennia and remains a public health issue today, as evidenced by the Covid-19 pandemic. Although the focus has traditionally centred on pathogens transmitted from animals to humans (zoonoses), the direction of transmission is also often the other way (reverse zoonoses). The best way to understand the cross-species transfer of pathogens is by investigating the conditions that make it possible for a new host, whether human or animal, to be infected. As societies transitioned from hunting and foraging to herding and farming, and from living in rural to urban settings, and in increasingly industrialised environments, dramatic changes occurred in their relationships with animals. These changes had major impacts on pathogen evolution. In particular, the new opportunities for transmission affected pathogen virulence and distribution. This chapter investigates the factors driving transmission of Taenia tapeworms, Mycobacteria, Plasmodium falciparum, Brucella, Burkholderia mallei and the morbilliviruses in domestic environments. It draws evidence from palaeopathology, historical sources, molecular analysis, paleoenvironmental data and medical/veterinary clinical literature. This approach helps explain why these pathogens became problematic when and where they did, and it identifies factors that are likely to contribute to future outbreaks. The chapter concludes with a reflection on the ways an interdisciplinary understanding of past diseases provides insights for current and future epidemics.
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