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Journal articles on the topic 'Reversible conveyor'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Oleh, Pihnastyi, Ivanovska Olha, and O. Sobol M. "Synthesis of the algorithm for the flow parameters optimal control of the reversible conveyor." Radio Electronics, Computer Science, Control 2022(2) (July 4, 2022): 210–21. https://doi.org/10.5281/zenodo.6941626.

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Context.  The problem of optimal control of flow parameters of a conveyor-type transport system containing sections with reversible conveyors is considered. The object of the stady was an analytical model of a reversible transport conveyor for synthesizing an algorithm for optimal control of the flow parameters of a reversible transport conveyor.   Objective.  The goal of the work is to develop a synthesis technique for an algorithm for optimal control of the flow parameters of a reversible transport conveyor based on an analytical model of a conveyor section containing a transp

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Gurskyi, Volodymyr, Vitaliy Korendiy, Pavlo Krot, and Oleksandr Dyshev. "Determination of kinematic and dynamic characteristics of a reversible vibratory conveyor with an electromagnetic drive." Vibroengineering Procedia 55 (September 27, 2024): 138–44. http://dx.doi.org/10.21595/vp.2024.24403.

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The paper considers the design parameters that must be provided during the practical implementation of small-sized reversible vibratory conveyors with an electromagnetic drive. The proposed conveyor is developed on the basis of a classical two-mass oscillatory system. Two oscillating masses are connected by symmetrically assembled round-shaped rods. In order to avoid angular (torsional) oscillations of the vibratory conveyor, the geometrical centers of mass and stiffness of the spring system are aligned at the same point. The analysis of kinematic characteristics is performed by means of numer

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Supandi, Supandi, Wahyu Isti Nugroho, and Iswanocta Candra Yudhistira. "Rancang Bangun dan Analisis Shutter Conveyor Reversible Semi”“Otomatis Berbasis PLC Guna Mengurangi Waktu Proses Material Handling Pada Line Assembly Steering Tipe D74 di PT. Akashi Wahana Indonesia." Journal of Mechanical Engineering and Applied Technology 1, no. 1 (2023): 25–31. https://doi.org/10.32497/jmeat.v1i1.4771.

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PT Akashi Wahana Indonesia is an automotive manufacturer that specializes in producing steering gear assemblies. The steering gear assembly process involves assembling the components of the steering gear into a single unit. A problem related to cycle time has been identified at a process position on the D74 steering gear assembly line. The cause of this issue is the manual shutter used to transfer assembly results between process positions, which requires manual intervention by operators, resulting in non-value-added time and unnecessary movement. The proposed solution to this problem is to de

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Klemiato, Maciej, and Piotr Czubak. "Control of the transport direction and velocity of the two-way reversible vibratory conveyor." Archive of Applied Mechanics 89, no. 7 (2019): 1359–73. http://dx.doi.org/10.1007/s00419-018-01507-8.

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Morard, S., R. Delaloye, and C. Lambiel. "Pluriannual thermal behavior of low elevation cold talus slopes in western Switzerland." Geographica Helvetica 65, no. 2 (2010): 124–34. http://dx.doi.org/10.5194/gh-65-124-2010.

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Abstract. The internal and reversible mechanism of air circulation (chimney effect) throughout a porous debris accumulation acts as an efficient advective conveyor of heat, which strongly influences its thermal balance during the whole year. Ground temperature monitoring carried out at eight sites located below the timberline in western Switzerland since 1997 indicates the major role played by winter air temperature conditions in the thermal regime of low elevation talus slopes and relict rock glaciers. In contrast, both snow depth and summer air temperatures have far less influence. The tempe

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Likharev, K., S. Rylov, and V. Semenov. "Reversible conveyer computation in array of parametric quantrons." IEEE Transactions on Magnetics 21, no. 2 (1985): 947–50. http://dx.doi.org/10.1109/tmag.1985.1063673.

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7

Dauhut, Thibaut, Jean-Pierre Chaboureau, Patrick Mascart, and Olivier Pauluis. "The Atmospheric Overturning Induced by Hector the Convector." Journal of the Atmospheric Sciences 74, no. 10 (2017): 3271–84. http://dx.doi.org/10.1175/jas-d-17-0035.1.

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Abstract The overturning of Hector the Convector, a tropical multicellular convective system of northern Australia that regularly overshoots into the stratosphere, is synthesized at the scale of a large-eddy simulation. The isentropic analysis offers the advantage of filtering out the reversible motions due to gravity waves and taking into account the turbulent fluxes that contribute to the vertical transport. Two key circulations are characterized: the troposphere deep overturning and the mass exchange due to the overshoots into the stratosphere. The transition from deep to very deep convecti

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Shukla, Vandana, O. P. Singh, G. R. Mishra, and R. K. Tiwari. "A Novel Approach to Design a 4-Bit Binary Comparator Circuit with Reversible Logic using CDSM Gate." International Journal of Business Data Communications and Networking 11, no. 1 (2015): 36–49. http://dx.doi.org/10.4018/ijbdcn.2015010104.

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In the recent scenario of microelectronic industry, the reversible logic is considered as the burgeonic technology for digital circuit designing. It deals with the aim to generate digital circuits with zero power loss characteristics. Optical computing, Nanotechnology, Low power CMOS design and Digital Signal Processing (DSP) processors are leading areas of development with the concept of reversible logic. Researchers have already proposed various subsystems of the computer for the creation of low power loss devices with the help of numerous available reversible logic gates. Here in this paper

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Amrein, R., S. R. Allen, T. W. Guentert, et al. "The Pharmacology of Reversible Monoamine Oxidase Inhibitors." British Journal of Psychiatry 155, S6 (1989): 66–71. http://dx.doi.org/10.1192/s0007125000297511.

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The older monoamine oxidase inhibitors (MAOIs) are mechanism-based, irreversible inhibitors of MAO; most inhibit both the A and B forms of MAO. Several of the drugs are hydrazine derivatives which have non-specific effects other than MAO inhibition. These properties convey disadvantages, which may be seen as serious, though infrequent, adverse events — the ‘cheese effect’, hepatotoxicity, amphetamine-like activity, orthostatic hypotension and anticholinergic effects. New, reversible MAOIs stem from a variety of chemical classes and are more specific in their effects, with relatively rapid onse

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Kalra, Sanjay, and Yashdeep Gupta. "Beta-cell Insufficiency." European Endocrinology 13, no. 02 (2017): 51. http://dx.doi.org/10.17925/ee.2017.13.02.51.

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‘B eta-cell failure’ is a frequently used term to describe the structural and functional inability of the cells to fulfil their metabolic responsibility. This editorial reviews the anatomy and physiology of the beta cell, and describes factors which regulate this. The authors focus on semantics, comparing the phrases ‘beta-cell failure’, ‘functional mass’, and ‘beta-cell insufficiency’. They suggest the use of ‘beta-cell insufficiency’, with descriptors such as ‘partial’ and ‘complete’, or ‘reversible’ and ‘irreversible’, to convey betacell dysfunction in type 2 diabetes. A three-phase taxonom

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Rios, William Q., Bruno Antunes, Alírio E. Rodrigues, Inês Portugal, and Carlos M. Silva. "Revisiting Isothermal Effectiveness Factor Equations for Reversible Reactions." Catalysts 13, no. 5 (2023): 889. http://dx.doi.org/10.3390/catal13050889.

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Ion exchange resins have many industrial applications, namely as sorbents and catalysts. In solid-catalyzed reactions, intraparticle reaction-diffusion competition is generally described by effectiveness factors calculated numerically or analytically in the case of isothermal particles and simple rate laws. Although robust, numerical calculations can be time-consuming, and convergence is not always guaranteed and lacks the flexibility of user-friendly equations. In this work, analytical equations for effectiveness factors of reversible reactions derived from the general scheme A+B⇌C+D are deve

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Chua, Mui Teng, Gene WH Chan, and Win Sen Kuan. "Reversible Causes in Cardiovascular Collapse at the Emergency Department Using Ultrasonography (REVIVE-US)." Annals of the Academy of Medicine, Singapore 46, no. 8 (2017): 310–16. http://dx.doi.org/10.47102/annals-acadmedsg.v46n8p310.

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Introduction: Ultrasonographic evaluation of patients in cardiac arrest is currently not protocolised in the advanced cardiac life support (ACLS) algorithm. Potentially reversible causes may be identified using bedside ultrasonography that is ubiquitous in most emergency departments (EDs). This study aimed to evaluate the incidence of sonographically detectable reversible causes of cardiac arrest by incorporating an ultrasonography protocol into the ACLS algorithm. Secondary objectives include rates of survival to hospital admission, hospital discharge, and 30-day mortality. Materials and Meth

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Murray, G. M., H. Q. Zhang, A. N. Kaye, T. Sinnadurai, D. H. Campbell, and M. J. Rowe. "Parallel processing in rabbit first (SI) and second (SII) somatosensory cortical areas: effects of reversible inactivation by cooling of SI on responses in SII." Journal of Neurophysiology 68, no. 3 (1992): 703–10. http://dx.doi.org/10.1152/jn.1992.68.3.703.

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1. Previous observations on the effect of ablation or inactivation of the primary somatosensory cortex (SI) on the responses of neurons within the second somatosensory area (SII) to tactile stimuli point to profound differences between monkeys and certain other mammals in the organization of thalamocortical systems. In the cat, for example, tactile information appears to be conveyed in parallel from the thalamus to both SI and SII, whereas, in macaque and marmoset monkeys, it is conveyed in a serial (or hierarchical) scheme from the thalamus to SI and thence to SII. The present study examined

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Hammond, Gerald R. V., Yirong Sim, Leon Lagnado, and Robin F. Irvine. "Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information." Journal of Cell Biology 184, no. 2 (2009): 297–308. http://dx.doi.org/10.1083/jcb.200809073.

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Polyphosphoinositol lipids convey spatial information partly by their interactions with cellular proteins within defined domains. However, these interactions are prevented when the lipids' head groups are masked by the recruitment of cytosolic effector proteins, whereas these effectors must also have sufficient mobility to maximize functional interactions. To investigate quantitatively how these conflicting functional needs are optimized, we used different fluorescence recovery after photobleaching techniques to investigate inositol lipid–effector protein kinetics in terms of the real-time dis

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Jacob, C., J. R. Lancaster, and G. I. Giles. "Reactive sulphur species in oxidative signal transduction." Biochemical Society Transactions 32, no. 6 (2004): 1015–17. http://dx.doi.org/10.1042/bst0321015.

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Intense interest has been generated by the discovery that reactive oxygen species can function as intracellular second messengers. Reactive oxygen species have been implicated in diverse cellular processes, including growth factor signal transduction, gene expression and apoptosis. Additionally, there is evidence for proteins that are regulated by redox environment through the reversible oxidation of their cysteine residues. However, the direct reaction of reactive oxygen species with cysteine at physiological concentrations is generally a slow process, suggesting that intermediates are requir

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Zhang, H. Q., G. M. Murray, A. B. Turman, P. D. Mackie, G. T. Coleman, and M. J. Rowe. "Parallel processing in cerebral cortex of the marmoset monkey: effect of reversible SI inactivation on tactile responses in SII." Journal of Neurophysiology 76, no. 6 (1996): 3633–55. http://dx.doi.org/10.1152/jn.1996.76.6.3633.

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1. Responsiveness within the hand region of the second somatosensory area of cortex (SII) was investigated in the marmoset monkey (Callithrix jacchus) in association with cooling-induced, reversible inactivation of the primary somatosensory area, SI. The aims were to determine whether thalamocortical systems in this primate species are organized according to a serial scheme in which tactile information is conveyed from the thalamus to SI and thence to SII as the next hierarchical level of processing and to establish whether primates are fundamentally different, in this respect, from mammals in

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Crow, Allister, Nicholas P. Greene, Elise Kaplan, and Vassilis Koronakis. "Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily." Proceedings of the National Academy of Sciences 114, no. 47 (2017): 12572–77. http://dx.doi.org/10.1073/pnas.1712153114.

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MacB is an ABC transporter that collaborates with the MacA adaptor protein and TolC exit duct to drive efflux of antibiotics and enterotoxin STII out of the bacterial cell. Here we present the structure of ATP-bound MacB and reveal precise molecular details of its mechanism. The MacB transmembrane domain lacks a central cavity through which substrates could be passed, but instead conveys conformational changes from one side of the membrane to the other, a process we term mechanotransmission. Comparison of ATP-bound and nucleotide-free states reveals how reversible dimerization of the nucleotid

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Jakopčević, Zrinka, Katarina Itrić Ivanda, Rahela Kulčar, Suzana Pasanec Preprotić, and Marina Vukoje. "Enhancing Applicability of Reversible UV Thermochromic Offset Inks: Edge Quality Parameters and Thermochromic Printing System Modulation Transfer Function." Materials 16, no. 8 (2023): 3125. http://dx.doi.org/10.3390/ma16083125.

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Modern logo design is characterized by its ability to convey information through the use of various images and text compositions. These designs often use simple elements such as lines to capture the essence of a product. When using thermochromic inks in logo design, it is important to consider their composition and behavior, as they differ significantly from conventional printing inks. This study aimed to determine the resolution capabilities of the dry offset printing technique when using thermochromic ink, with the ultimate goal of optimizing the thermochromic ink printing process. Horizonta

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Suethao, Supitta, Thridsawan Prasopdee, Kwanchai Buaksuntear, Darshil U. Shah, and Wirasak Smitthipong. "Recent Developments in Shape Memory Elastomers for Biotechnology Applications." Polymers 14, no. 16 (2022): 3276. http://dx.doi.org/10.3390/polym14163276.

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Shape memory elastomers have revolutionised the world since their introduction in the 20th century. The ability to tailor chemical structures to produce a family of materials in wide-ranging forms with versatile properties has propelled them to be ubiquitous. Recent challenges in the end-of-life management of polymeric materials should prompt us to ask, ‘what innovations in polymeric materials can make a strong case for their use as efficient materials?’ The development of smart elastomers that can acquire, convey, or process a stimulus (such as temperature, pressure, electromagnetic field, mo

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Matamoros, Manuel A., Maria C. Cutrona, Stefanie Wienkoop, et al. "Altered Plant and Nodule Development and Protein S-Nitrosylation in Lotus japonicus Mutants Deficient in S-Nitrosoglutathione Reductases." Plant and Cell Physiology 61, no. 1 (2019): 105–17. http://dx.doi.org/10.1093/pcp/pcz182.

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Abstract Nitric oxide (NO) is a crucial signaling molecule that conveys its bioactivity mainly through protein S-nitrosylation. This is a reversible post-translational modification (PTM) that may affect protein function. S-nitrosoglutathione (GSNO) is a cellular NO reservoir and NO donor in protein S-nitrosylation. The enzyme S-nitrosoglutathione reductase (GSNOR) degrades GSNO, thereby regulating indirectly signaling cascades associated with this PTM. Here, the two GSNORs of the legume Lotus japonicus, LjGSNOR1 and LjGSNOR2, have been functionally characterized. The LjGSNOR1 gene is very acti

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Deutsch, Harel, Marc Arginteanu, Karen Manhart, et al. "Somatosensory evoked potential monitoring in anterior thoracic vertebrectomy." Journal of Neurosurgery: Spine 92, no. 2 (2000): 155–61. http://dx.doi.org/10.3171/spi.2000.92.2.0155.

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Object. Spine surgeons have used intraoperative cortical and subcortical somatosensory evoked potential (SSEP) monitoring to detect changes in spinal cord function when intraoperative procedures can be performed to prevent neurological deterioration. However, the reliability of SSEP monitoring as applied to anterior thoracic vertebral body resections has not been rigorously assessed. Methods. The authors retrospectively reviewed hospital charts and operating room records obtained between August 1993 and December 1998 and found that SSEP monitoring was used in 44 surgical procedures involving a

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Sullivan, Shannon D., та Suzanne M. Moenter. "γ-Aminobutyric Acid Neurons Integrate and Rapidly Transmit Permissive and Inhibitory Metabolic Cues to Gonadotropin-Releasing Hormone Neurons". Endocrinology 145, № 3 (2004): 1194–202. http://dx.doi.org/10.1210/en.2003-1374.

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Abstract Negative energy balance inhibits fertility by decreasing GnRH release; however, the mechanisms are not well understood. GnRH neurons can be excited by activation of γ-aminobutyric acid (GABA)A receptors, and GABAergic neurons provide a major synaptic input. We hypothesized that permissive metabolic signals mediated by leptin and inhibitory signals conveyed by neuropeptide Y (NPY) and opiates rapidly alter GABAA receptor-mediated drive to GnRH neurons. In fed and fasted female mice, GABAergic postsynaptic currents (PSCs) were recorded from GnRH neurons before and after in vitro treatme

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Przybylska, Ewa Małgorzata, and Danuta Wajsprych. "Experiencing parenthood in early adulthood." Family Forum 9 (February 27, 2020): 151–72. http://dx.doi.org/10.25167/ff/1094.

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This article attempts to present ways of experiencing parenthood among 17 young adults who have become mothers/fathers. The study was carried out using the phenomenographic method, which sought to describe how the young parents gave meanings to the phenomenon of parenthood; what it meant for them to be a parent. Based on the approach designed by the creators of the phenomenographic research method, we made the epistemological assumption that there is no other world besides the one that an individual experiences. A family was recognised as a special place for learning and experiencing the world

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Aubry, Clémentine, Christophe Drouet, Thierry Azaïs та ін. "Bio-Activation of HA/β-TCP Porous Scaffolds by High-Pressure CO2 Surface Remodeling: A Novel “Coating-from” Approach". Materials 15, № 20 (2022): 7306. http://dx.doi.org/10.3390/ma15207306.

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Biphasic macroporous Hydroxyapatite/β-Tricalcium Phosphate (HA/β-TCP) scaffolds (BCPs) are widely used for bone repair. However, the high-temperature HA and β-TCP phases exhibit limited bioactivity (low solubility of HA, restricted surface area, low ion release). Strategies were developed to coat such BCPs with biomimetic apatite to enhance bioactivity. However, this can be associated with poor adhesion, and metastable solutions may prove difficult to handle at the industrial scale. Alternative strategies are thus desirable to generate a highly bioactive surface on commercial BCPs. In this wor

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Chakrabarti, Shubhodeep, Mengliang Zhang, and Kevin D. Alloway. "MI Neuronal Responses to Peripheral Whisker Stimulation: Relationship to Neuronal Activity in SI Barrels and Septa." Journal of Neurophysiology 100, no. 1 (2008): 50–63. http://dx.doi.org/10.1152/jn.90327.2008.

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The whisker region in the rodent primary motor (MI) cortex receives dense projections from neurons aligned with the layer IV septa in the whisker region of the primary somatosensory (SI) cortex. To compare whisker-induced responses in MI with respect to the SI responses in the septa and adjoining barrel regions, we used several experimental approaches in anesthetized rats. Reversible inactivation of SI and the surrounding cortex suppressed the magnitude of whisker-induced responses in the MI whisker region by 80%. Subsequent laminar analysis of MI responses to electrical or mechanical stimulat

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Polkey, M. I. "Endobronchial blockers for lung volume reduction." Breathe 4, no. 4 (2008): 339–41. https://doi.org/10.1183/18106838/breathe.4.4.339.

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Educational aimsTo understand how endobronchial valves can improve symptoms in patients with emphysema and to convey current opinion regarding optimal patient selection.SummarySurgical lung volume reduction can, under certain circumstances, improve forced expiratory volume in one second (FEV1), indices of resting hyperinflation and quality of life [1] in patients with emphysema. However, a significant proportion of patients (between one-quarter and one-third) fail to derive significant benefit from the procedure. This in itself might not matter were it not that, in large series, the mortality

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Love, Corey T., Matthew J. Lefler, Chris Rudolf, and Junghoon Yeom. "(Invited) Opportunities for Bulk Silicon As a High Capacity Lithium Host." ECS Meeting Abstracts MA2022-01, no. 38 (2022): 1659. http://dx.doi.org/10.1149/ma2022-01381659mtgabs.

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Silicon, the earth’s second most abundant element ushered in new age of computing capability. More recently, silicon is enjoying a second wave of technological adoption as a constituent of lithium-ion battery negative electrodes; made possible in practice by reducing the dimensions to the nanoscale and/or compositing with traditional carbon-based lithium host materials. The large lithium capacity and subsequent volumetric expansion and mechanical fracture have been documented extensively and the nano and composite routes mentioned above provide strategies to overcome this obstacle. We take a n

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Guyenet, P. G., R. A. Darnall, and T. A. Riley. "Rostral ventrolateral medulla and sympathorespiratory integration in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 259, no. 5 (1990): R1063—R1074. http://dx.doi.org/10.1152/ajpregu.1990.259.5.r1063.

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The respiratory modulation of the lumbar sympathetic nerve discharge (LSND) was examined in halothane-anesthetized, paralyzed, and vagotomized rats by means of phrenic nerve discharge (PND)-triggered histograms. The respiratory modulation was 1) proportional to PND amplitude during chemoreceptor activation with CO2 and 2) reduced at elevated arterial pressure. Bilateral injections of bicuculline [gamma-aminobutyric acid (GABA)A receptor antagonist, n = 5] into the rostral ventrolateral medulla (RVLM), but not into medullary raphe, reversibly increased mean arterial pressure (MAP) and resting L

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Bartness, Timothy J., C. Kay Song, Haifei Shi, Robert R. Bowers, and Michelle T. Foster. "Brain–adipose tissue cross talk." Proceedings of the Nutrition Society 64, no. 1 (2005): 53–64. http://dx.doi.org/10.1079/pns2004409.

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While investigating the reversible seasonal obesity of Siberian hamsters, direct sympathetic nervous system (SNS) postganglionic innervation of white adipose tissue (WAT) has been demonstrated using anterograde and retrograde tract tracers. The primary function of this innervation is lipid mobilization. The brain SNS outflow to WAT has been defined using the pseudorabies virus (PRV), a retrograde transneuronal tract tracer. These PRV-labelled SNS outflow neurons are extensively co-localized with melanocortin-4 receptor mRNA, which, combined with functional data, suggests their involvement in l

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Tups, Alexander, Claire Ellis, Kim M. Moar, et al. "Photoperiodic Regulation of Leptin Sensitivity in the Siberian Hamster, Phodopus sungorus, Is Reflected in Arcuate Nucleus SOCS-3 (Suppressor of Cytokine Signaling) Gene Expression." Endocrinology 145, no. 3 (2004): 1185–93. http://dx.doi.org/10.1210/en.2003-1382.

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Abstract We present the first evidence that suppressor of cytokine signaling-3 (SOCS3), a protein inhibiting Janus kinase/signal transducer and activator of transcription (STAT) signaling distal of the leptin receptor, conveys seasonal changes in leptin sensitivity in the Siberian hamster. Food deprivation (48 h) reduced SOCS3 gene expression in hamsters acclimated to either long (LD) or short (SD) photoperiods, suggesting that leptin signals acute starvation regardless of photoperiod. However, SOCS3 mRNA levels were substantially lower in the hypothalamic arcuate nucleus of hamsters acclimate

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Kemp, Louise E., Marion Rusch, Alexander Adibekian, et al. "Characterization of a Serine Hydrolase Targeted by Acyl-protein Thioesterase Inhibitors in Toxoplasma gondii." Journal of Biological Chemistry 288, no. 38 (2013): 27002–18. http://dx.doi.org/10.1074/jbc.m113.460709.

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In eukaryotic organisms, cysteine palmitoylation is an important reversible modification that impacts protein targeting, folding, stability, and interactions with partners. Evidence suggests that protein palmitoylation contributes to key biological processes in Apicomplexa with the recent palmitome of the malaria parasite Plasmodium falciparum reporting over 400 substrates that are modified with palmitate by a broad range of protein S-acyl transferases. Dynamic palmitoylation cycles require the action of an acyl-protein thioesterase (APT) that cleaves palmitate from substrates and conveys reve

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Kleinehr, Jens, Michael Schöfbänker, Katharina Daniel, et al. "Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA." PLOS Pathogens 19, no. 7 (2023): e1010986. http://dx.doi.org/10.1371/journal.ppat.1010986.

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Influenza A virus (IAV), like any other virus, provokes considerable modifications of its host cell’s metabolism. This includes a substantial increase in the uptake as well as the metabolization of glucose. Although it is known for quite some time that suppression of glucose metabolism restricts virus replication, the exact molecular impact on the viral life cycle remained enigmatic so far. Using 2-deoxy-d-glucose (2-DG) we examined how well inhibition of glycolysis is tolerated by host cells and which step of the IAV life cycle is affected. We observed that effects induced by 2-DG are reversi

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Campbell, Victoria, Harriet Walter, Adam Gibb, et al. "Preclinical and Early Clinical Results Indicate a Role for the Oral p300/CBP Inhibitor Inobrodib (CCS1477) in T-Cell Lymphoma." Blood 142, Supplement 1 (2023): 5795. http://dx.doi.org/10.1182/blood-2023-187378.

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Inobrodib (CCS1477) is a potent, selective, and orally bioavailable inhibitor of the bromodomains of CBP and EP300, two homologous histone acetyltransferases with critical roles in cellular growth and differentiation. Lymphomas can harbor multiple putative predictive biomarkers for inobrodib, including deleterious mutations in CBP/EP300 that convey synthetic lethality and expression of the lineage transcription factors IRF4 and GATA3. The preclinical efficacy of inobrodib was assessed in a range of solid cancer and hematological cancer cell lines. Select models, including multiple myeloma, acu

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DENHARDT, David T. "Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling." Biochemical Journal 318, no. 3 (1996): 729–47. http://dx.doi.org/10.1042/bj3180729.

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The features of three distinct protein phosphorylation cascades in mammalian cells are becoming clear. These signalling pathways link receptor-mediated events at the cell surface or intracellular perturbations such as DNA damage to changes in cytoskeletal structure, vesicle transport and altered transcription factor activity. The best known pathway, the Ras → Raf → MEK → ERK cascade [where ERK is extracellular-signal-regulated kinase and MEK is mitogen-activated protein (MAP) kinase/ERK kinase], is typically stimulated strongly by mitogens and growth factors. The other two pathways, stimulated

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Faried, Annisa Ilmi, Rahmad Sembiring, and Maya Macia Sari. "Building an Anti-Stunting Village before Genting Based on the Role of Thematic Real Work Lecture (KKNT) Students in Simpang Tiga Sawit Village, Seberang Langkat Regency, Langkat Regency." International Journal of Research and Review 10, no. 2 (2023): 65–77. http://dx.doi.org/10.52403/ijrr.20230210.

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In Indonesia, the National Strategy (Stranas) for the Acceleration of Stunting Child Prevention for the 2018–2024 period is a guide document for the implementation framework for stunting reduction. Following up on this, the government issued Presidential Regulation (Perpres) Number 72 of 2021 concerning the Acceleration of Stunting Reduction with the intention of strengthening the intervention and institutional framework in the process of implementing the acceleration of stunting reduction. A condition known as stunting occurs when a child's height is much lower than expected for their age. In

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Davis, L., and P. E. Lipsky. "Signals involved in T cell activation. I. Phorbol esters enhance responsiveness but cannot replace intact accessory cells in the induction of mitogen-stimulated T cell proliferation." Journal of Immunology 135, no. 5 (1985): 2946–52. http://dx.doi.org/10.4049/jimmunol.135.5.2946.

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Abstract The role of accessory cells (AC) in the initiation of mitogen-induced T cell proliferation was examined by comparing the effect of intact macrophages (M phi) with that of 4-beta-phorbol 12-myristate 13-acetate (PMA). In high-density cultures, purified guinea pig T cells failed to proliferate in response to stimulation with phytohemagglutinin (PHA), concanavalin A (Con A), or PMA alone. The addition of M phi to PHA or Con A but not PMA-stimulated cultures restored T cell proliferation. The addition of PMA to high-density T cell cultures stimulated with PHA or Con A also permitted [3H]t

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Chernysheva, L. M. "The word order in an Udmurt sentence: towards the history of learning." BULLETIN OF UGRIC STUDIES 14, no. 3 (2024): 498–510. https://doi.org/10.30624/2220-4156-2024-14-3-498-510.

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the article devoted to the neutral and inverted word order in an Udmurt sentence, on the basis of which a periodization of the consideration of the issue is proposed. Objective: to identify the stages of the study of the word order in an Udmurt sentence from the point of view of the consideration of inversion and neutral word order by Finno-Ugric scholars in the XIX–XX centuries. Research materials: scientific research of domestic and foreign scientists devoted to the issues of syntax, word order and stylistics in the Udmurt language. Results and novelty of the research: for the first the arti

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Meftah, E. M., and L. Rispal-Padel. "Synaptic plasticity in the thalamo-cortical pathway as one of the neurobiological correlates of forelimb flexion conditioning: electrophysiological investigation in the cat." Journal of Neurophysiology 72, no. 6 (1994): 2631–47. http://dx.doi.org/10.1152/jn.1994.72.6.2631.

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1. In a previous study, using a chronic cat preparation subjected to an associative conditioning procedure, we described the plasticity of the thalamo-cortical pathway by qualitatively and quantitatively analyzing the motor responses induced by stimulating each of the relays on the cerebello-thalamo-cortical pathway. In the present study, it was proposed to analyze the effects on the synapses located between thalamic endings and cortical neurones, using a twofold behavioral and electrophysiological approach, with a view to correlating the patterns of synaptic plasticity with the changes in the

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Yun, Jonghyeok, Hong Rim Shin, Eun-Seo Won, and Jong-Won Lee. "Li Metal Storage in Porous Carbon Frameworks: Effect of Li–Substrate Interaction." ECS Meeting Abstracts MA2022-01, no. 4 (2022): 529. http://dx.doi.org/10.1149/ma2022-014529mtgabs.

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Lithium-metal electrodes are of particular interest for next-generation rechargeable batteries because of their high specific capacity and low redox potential. Therefore, Li-metal-based batteries may afford higher energy densities than commercially available Li-ion batteries with graphite anodes. However, various bottlenecks have hampered the commercial development of these batteries, including uncontrolled Li dendrite formation and huge volume changes during cycling. Consequently, Li-metal batteries suffer from low Coulombic efficiency and poor cycling stability. In recent years, there has be

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Wyseure, Tine L., Esther J. Cooke, Paul J. Declerck, Joost CM Meijers, Annette von Drygalski, and Laurent O. Mosnier. "Defective TAFI Activation in Hemophilia Exacerbates Vascular Remodeling in Hemophilic Arthropathy." Blood 128, no. 22 (2016): 82. http://dx.doi.org/10.1182/blood.v128.22.82.82.

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Abstract Introduction: Patients with hemophilia A or B develop hemophilic arthropathy (HA), characterized by inflammation, cell proliferation, and hypervascularity in the synovial joint tissue. The hypervascular response in HA results in aberrant vascular remodeling and the formation of enlarged, irregularly shaped and leaky vessels, which are prone to bleeding. Recently, we showed that after a single joint bleed in FVIII-/- mice changes in soft tissue proliferation, neo-angiogenesis, and cartilage destruction were reversible, whereas vascular remodeling in the joint became progressively worse

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Liang, Hengdi, James W. Moffett, and Seth G. John. "Toward a Better Understanding of the Global Ocean Copper Distribution and Speciation through a Data‐constrained Model." Global Biogeochemical Cycles, August 30, 2023. http://dx.doi.org/10.1029/2023gb007769.

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AbstractCopper (Cu) is an important micronutrient for marine organisms which can also be toxic at elevated concentrations. Here we present a new model of global ocean Cu biogeochemical cycling, constrained by GEOTRACES observations, with key processes including sources from rivers, dust, and sediments, biological uptake and remineralization of Cu, reversible scavenging of Cu onto sinking particles, conversion of Cu between labile and inert species, and ocean circulation. In order for the model to match observations, in particular the relatively small increase in Cu concentrations along the glo

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Rathod, Nishadh, Joanne Lemieux, Christophe Chipot, Benoit Roux, and Howard Young. "Probing the formation of a hetero-dimeric membrane transport complex with dual in vitro and in silico mutagenesis." Chemical Science, 2024. http://dx.doi.org/10.1039/d4sc02915a.

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The reversible association of transmembrane helices is a fundamental mechanism in how living cells convey information and respond to physiological events. The cardiac calcium transport regulator phospholamban (PLN) is an...

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Pimmett, Virginia L., James McGehee, Antonio Trullo, et al. "Optogenetic manipulation of nuclear Dorsal reveals temporal requirements and consequences for transcription." Development, February 28, 2025. https://doi.org/10.1242/dev.204706.

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Morphogen gradients convey essential spatial information during tissue patterning. While both concentration and timing of morphogen exposure are crucial, how cells interpret these graded inputs remains challenging to address. We employed an optogenetic system to acutely and reversibly modulate the nuclear concentration of the morphogen Dorsal (DL), homologue of NF-κB, which orchestrates dorso-ventral patterning in the Drosophila embryo. By controlling DL nuclear concentration while simultaneously recording target gene outputs in real time, we identified a critical window for DL action that is

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"Fredkin Gates Based Testable Reversible Shift Registers." International Journal of Innovative Technology and Exploring Engineering 8, no. 11S2 (2019): 154–63. http://dx.doi.org/10.35940/ijitee.k1025.09811s219.

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in this paper, we recommend the connection of testable skip registers counting on conformist purpose passages. The proposed detour registers trouble to coordinate protection gateways can play out the flow registers located out in antique fashion entries to the quantity testability. Any reduction lower once more to convey down some unique time circuit situation to those slight method of thinking doors is probably preferred for normal unidirectional stuck-at deficiencies making use of awesome take a look at vectors. those are all of the 1s, and all of the 0s. The systems of vectors testable skip

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Schouwstra, Marieke, Danielle Naegeli, and Simon Kirby. "Investigating Word Order Emergence: Constraints From Cognition and Communication." Frontiers in Psychology 13 (April 22, 2022). http://dx.doi.org/10.3389/fpsyg.2022.805144.

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How do cognitive biases and mechanisms from learning and use interact when a system of language conventions emerges? We investigate this question by focusing on how transitive events are conveyed in silent gesture production and interaction. Silent gesture experiments (in which participants improvise to use gesture but no speech) have been used to investigate cognitive biases that shape utterances produced in the absence of a conventional language system. In this mode of communication, participants do not follow the dominant order of their native language (e.g., Subject-Verb-Object), and inste

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Samson Kastro Dake and Temesgen Lera Abiso. "Reversible Long Term Contraceptives Utilization among Married Women of Reproductive Age Group in Areka Town, Southern Ethiopia." Ethiopian Journal of Health Sciences 30, no. 6 (2020). http://dx.doi.org/10.4314/ejhs.v30i6.9.

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BACKGROUND፡ In low income countries, bearing many children is the main factor affecting maternal health. This study aimed to estimate the prevalence of reversible long term contraceptives utilization and identify factors associated with it among married women of child bearing age in Areka District in South EthiopiaMETHODS: We conducted a community-based cross-sectional survey involving systematically recruited 346 married women of reproductive age group. Data was collected using a structured interviewer-administered questionnaire on May 2019. We used SPSS version 25 for data entry and analyses

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Mishra, Sonali, Gajendra K. Yadav, Rohit Gupta, and Arvind Kumar. "Resin related enterocolitis: An underreported co-occurrence." Indian Journal of Pathology and Microbiology, July 19, 2023. http://dx.doi.org/10.4103/ijpm.ijpm_627_22.

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ABSTRACT Medication resins are often encountered in gastrointestinal biopsy specimens of patients being treated for renal compromise. As important as they are for the electrolyte equilibrium of the patients, they often come with a cost of fatal but reversible damage to the gastrointestinal tract. This often manifests as inflammatory bowel disease in the affected individuals. This misleading manifestation coupled with the lack of patient history further masks resin-related colitis from a pathologist’s eyes. Through this report, we convey how meticulous history-taking, representative endoscopic

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Luo, Yuanjing, Xichen Tan, Jiaohua Qin, and Zhiping Cai. "BlkInfoM: versatile blockchain-based mapping mechanism for secure information transmission." Computer Journal, July 20, 2025. https://doi.org/10.1093/comjnl/bxaf088.

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Abstract Information mapping is a widely adopted strategy in information hiding, leveraging the inherent features of carriers to convey hidden information without altering the carrier itself, thus maintaining integrity and avoiding detection. However, current mapping-based techniques face significant challenges, including potential data loss during transmission, limited capacity of carriers like images, and reliance on costly third-party storage solutions. To address these limitations, we introduce BlkInfoM, an innovative algorithm that utilizes blockchain’s decentralized, immutable, and trace

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Heidrich, Bastian, Maik Stamm, Olga Fromm, et al. "Determining the Origin of Lithium Inventory Loss in NMC622||Graphite Lithium Ion Cells Using an LiPF6-Based Electrolyte." Journal of The Electrochemical Society, January 17, 2023. http://dx.doi.org/10.1149/1945-7111/acb401.

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Abstract X-ray photoelectron spectroscopy (XPS) is often used in interphase investigations of lithium ion batteries (LIBs), yet it is unclear if its results convey an accurate picture of the lithium loss in aged LIBs. Herein, electrochemical and surface analytical approaches were used to separately quantify the contribution of interphase growth to lithium loss in LIBs. For this, LIB pouch cells (NMC622||graphite, 5 Ah) were aged for 400 full cycles at 20 or 60°C. Electrodes were harvested post mortem and subsequent investigations in lithium metal battery cells showed notably higher reversible

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Yang, Jingchun, and Xiaolei Xu. "Abstract 190: A Mechanotransduction Study In Embryonic Zebrafish Heart." Circulation Research 113, suppl_1 (2013). http://dx.doi.org/10.1161/res.113.suppl_1.a190.

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Background: While proper heart contraction requires an intact sarcomere structure, contraction reciprocally regulates sarcomere assembly and cardiomyocyte shape during heart morphogenesis and heart remodeling. However, how contraction modulates heart morphogenesis and the underlying molecular mechanism remains unclear. Here we address this question by manipulating cardiac contractility in a developing zebrafish embryo. Results: Cessation of heart contraction was achieved by treating zebrafish embryos with blebbistatin, a myosin II specific inhibitor, or Niferdipine, a Ca 2+ channel inhibitor.

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