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1

Chen, Xia, Lina Guo, and Qamar Ul Islam. "Revolutionizing E-Commerce Logistics." International Journal of Information Technologies and Systems Approach 17, no. 1 (2024): 1–15. http://dx.doi.org/10.4018/ijitsa.355016.

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The traditional approach to logistics path planning is hindered by lengthy procedures. In this study, we explore the multi-objective optimization of logistics management, considering the conventional path and time efficiency indices alongside shelf safety and stability as additional objective functions. Based on particle swarm optimization (PSO), we optimize objective functions for internal path planning, scheduling timeliness, and shelf safety and stability. We then determine optimal routes under varying order demands using PSO and ultimately optimize the final path using dynamic programming
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Harshad, Tanpure* Dr. Vishwas Bahgat Dr. Deepak Kardile Dr. Rajkumar Shete M. M. Karne. "Revolutionizing Stability-Indicating Analysis: Advanced RP-HPLC Strategies for Pharmaceutical Excellence." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4466–89. https://doi.org/10.5281/zenodo.15522235.

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Stability-indicating analysis is vital to pharmaceutical quality control for establishing the safety, efficacy, and quality of pharmaceutical drug products until their expiration date. Reversed-phase high-performance liquid chromatography (RP-HPLC) has recently become an important tool in stability testing because of its high selectivity, sensitivity, and robustness. Abstract/Short: This review focused on recent developments in RP-HPLC approaches for stability-indicating analysis to emphasize their importance in pharmaceutical excellency. Abstract The principles of stability-ind
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Sumaiya, P.S, George Sweety, R.P. Thamanna, and D. Manesh. "Alpha-Fold 3: Revolutionizing Drug Design, Protein Stability, Allostery, and Ai-Driven Therapeutics." Journal of Research and Review: Fuzzy Logic Design and Fuzzy Systems 1, no. 1 (2025): 10–18. https://doi.org/10.5281/zenodo.15104811.

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<em>AlphaFold, an AI-driven protein structure prediction system developed by DeepMind, has revolutionized structural biology by achieving remarkable accuracy in protein modeling. By leveraging deep learning techniques, AlphaFold provides high-resolution three-dimensional protein structures, surpassing traditional experimental methods in speed and efficiency. Its applications span drug discovery, cancer research, genomics, and bioengineering, aiding in mutation impact analysis, molecular simulations, and personalized medicine. Despite its success, AlphaFold faces challenges in modeling intrinsi
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Kallingal, Akshay. "REVOLUTIONIZING DRUG DELIVERY: CUBOSOMES NANOPARTICLES AT THE FOREFRONT." Global Journal of Medical and Pharmaceutical Sciences 03, no. 01 (2024): 01–06. http://dx.doi.org/10.55640/gjmps-abcd114.

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Cubosomes nanoparticles represent an innovative approach in drug delivery systems, offering unique advantages over traditional delivery methods. This paper explores recent advancements in cubosomes nanoparticles technology and their potential applications in pharmaceutical formulations. We discuss the structural characteristics, fabrication methods, and key properties of cubosomes nanoparticles, highlighting their ability to encapsulate hydrophilic and hydrophobic drugs, enhance drug stability, and facilitate controlled release. Furthermore, we examine the promising applications of cubosomes n
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Nasrin, Nasir*1 Preetha S. Panicker2 Keerthi R.3 Farsana P. P.4. "Nanoparticles: The Invisible Giants Revolutionizing Our World." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 1044–52. https://doi.org/10.5281/zenodo.12739631.

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This review dives into the fascinating world of nanoparticles (NPs), exploring their creation, properties, and diverse uses. NPs are incredibly small materials, typically ranging from 1 to 100 nanometers (nm) in size. They come in various forms, including organic, inorganic (metals, ceramics, polymers), and fullerenes. The unique properties of NPs, largely due to their tiny size, are revolutionizing many fields. Their high surface area, reactivity, stability, and sensitivity make them highly desirable for various applications.Multiple synthesis methods exist for creating NPs, enabling research
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Indresh, Kumar* Sanjay Kushwaha. "Emulgels: Revolutionizing Topical and Transdermal Drug Delivery." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 2840–50. https://doi.org/10.5281/zenodo.15270702.

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Emulgels are a groundbreaking hybrid drug delivery system that combines the solubility-enhancing benefits of emulsions with the controlled-release properties of gels. This biphasic formulation excels in topical and transdermal applications, enhancing drug stability, bioavailability, and skin permeation for both hydrophilic and lipophilic active pharmaceutical ingredients. Emulgels provide sustained release, improved patient compliance, and reduced systemic side effects compared to traditional creams, ointments, and gels. This review offers a comprehensive exploration of emulgel composition, dr
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R.Patil, Sneha, Vishveshwar Dharashive, Sameer Shafi, Muktai N. Rudrurkar, Anis J. Kazi, and Punam V. Ritthe. "Transethosome Technology: Revolutionizing Transdermal Drug Delivery." Asian Journal of Pharmaceutical Research and Development 12, no. 3 (2024): 102–9. http://dx.doi.org/10.22270/ajprd.v11i3.1402.

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In recent years, transdermal drug delivery has become increasingly popular as it overcomes issues with oral administration. The main challenge in this method is the complex stratum corneum barrier that prevents the transdermal administration of drugs. However, modern lipid-based nanosystems, particularly transethosomes, can effectively penetrate the dense network of the stratum corneum. Transethosomes are a promising and unique technique for improved transdermal medication administration via the skin, as compared to transferosomes and ethosomes. They are composed of phospholipid, ethanol, wate
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Cramer, Claire E., Chih-Hao Li, Andrew J. Benedick, et al. "Astro-comb: revolutionizing precision spectroscopy in astrophysics." Proceedings of the International Astronomical Union 4, S253 (2008): 499–501. http://dx.doi.org/10.1017/s174392130802704x.

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AbstractSearches for extrasolar planets using the periodic Doppler shift of stellar spectral lines have recently achieved a precision better than 60cm/s. To find a 1-Earth mass planet in an Earth-like orbit, a precision of 5cm/s is necessary. The combination of a laser frequency comb with a Fabry-Perot filtering cavity has been suggested as a promising approach to achieve such Doppler shift resolution via improved spectrograph wavelength calibration. Here we report the fabrication of such a filtered laser comb with up to 40 GHz (~1 Angstrom) line spacing, generated from a 1 GHz repetition-rate
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Bharadwaj, Abhishek. "Revolutionizing perioperative medicine: Technological advancements for enhanced recovery." Serbian Journal of Anesthesia and Intensive Therapy 47, no. 1-2 (2025): 5–16. https://doi.org/10.5937/sjait2502005b.

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Enhanced Recovery After Surgery (ERAS) is a multimodal, evidence-based approach designed to minimize surgical stress, accelerate recovery, and improve patient outcomes. Recent technological advancements have transformed ERAS protocols by integrating robotic-assisted surgery, artificial intelligence (AI)-driven monitoring, advanced thermoregulation, automated nutrition management, and real-time perioperative decision support. These innovations enhance surgical precision, metabolic stability, pain control, and personalized patient care, ultimately reducing complications and improving recovery ef
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Javaid, Sumiyya, Tayyaba Rana, Muhammad Zaman, Zainab Naeem, and Azeem Ahmed Iqbal. "Revolutionizing Hyperpigmentation Solutions: Formulation and Characterization of Kojic Acid Gel." Currents in Pharmaceutical Research 2, no. 2 (2024): 55–88. https://doi.org/10.32350/cpr.22.04.

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Kojic acid is a skin-lightening agent that blocks the tyrosinase enzyme and inhibits melanin synthesis. While kojic acid has demonstrated effectiveness in hyperpigmentation treatment, the existing formulations often suffer from issues, such as poor skin penetration, instability, and skin irritation. The current study aimed to overcome these limitations by preparing a kojic acid gel formulation utilizing biocompatible polymers. These polymers included sodium alginate and xanthan gum to enhance therapeutic efficacy for hyperpigmentation treatment. Sodium alginate and xanthan gum were used as pol
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Prabhakar, Pranav Kumar, Keshav Anand, Indu Bala, et al. "Revolutionizing Herbal Medicine: Exploring Nano Drug Delivery Systems." Sumatera Medical Journal 6, no. 3 (2023): 210–26. http://dx.doi.org/10.32734/sumej.v6i3.12799.

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Abstract. Introduction: Traditional herbal medicine has been practiced for centuries and continues to play a significant role in healthcare systems worldwide. However, the efficacy and therapeutic potential of herbal remedies can be limited due to various factors such as poor bioavailability, instability, and non-specific targeting. In recent years, nanotechnology has emerged as a promising approach to overcome these limitations and revolutionize the field of herbal medicine. This review explores the application of nano drug delivery systems in enhancing the effectiveness of herbal therapeutic
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Tamboli, Firoj Allauddin, Rupali Sugram Waghmare, Sharayu Rajkumar Gajewar, et al. "Nano Nutraceuticals: Revolutionizing the Future of Health Supplements." Biomedical and Pharmacology Journal 18, no. 1 (2025): 459–70. https://doi.org/10.13005/bpj/3100.

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A promising new avenue for improving health and wellness is presented by the combination of nutraceuticals with nanotechnology. The application of nanotechnology to nutraceuticals is examined in this abstract, with particular attention on how it might transform bioactive substances' bioavailability, efficacy, and delivery methods. With nanotechnology's exact manipulation at the nanoscale, new delivery vehicles, including liposomes, nanoparticles, and nanoemulsions, can be designed. These platforms solve problems with traditional formulations by enhancing nutraceutical chemicals' solubility and
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Pandey, Adarsh, Megha Kumari, Muskan Kadyan, Debabrata Dhar, and Shakti Om Pathak. "Nano Fertilizers: Revolutionizing Agriculture for a Sustainable Future." Asian Journal of Soil Science and Plant Nutrition 10, no. 4 (2024): 246–60. http://dx.doi.org/10.9734/ajsspn/2024/v10i4400.

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Nanotechnology, one of the advanced fields of study, is currently the focus of contemporary science and one of the most important ones in physics, chemistry, agriculture, and other fields. Nanotechnology provides superior quality, environmental safety, biological support, and financial stability as an environmentally sound substitute for traditional agriculture. Utilizing nanoparticles (NPs) in agriculture has introduced recently; examples like biosynthesis, the use of nanopesticides and fertilizers, improving biological function, and reducing heavy metal toxicity and abiotic stress. To focus
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Gherghinoiu, Dragoș. "Smart Bullets: Revolutionizing Precision Warfare and Tactical Capabilities." Scientific Bulletin 29, no. 1 (2024): 26–32. http://dx.doi.org/10.2478/bsaft-2024-0004.

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Abstract Smart bullets, developed under programs such as the Defense Advanced Research Projects Agency (DARPA), represent a groundbreaking advancement in precision warfare. This article offers a comprehensive review and critical analysis of smart bullet technology, exploring its technical intricacies, military applications, ethical implications, economic considerations, and future prospects. By integrating advanced optical sensors, guidance systems, and maneuverability mechanisms, smart bullets achieve unparalleled accuracy and lethality on the battlefield. Military applications range from pre
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Kumar, Pramod, Shrimohan Shrivastava, Zeeshan Ansari, Ayush Chaurasia, Vishal Chauhan, and Pallavi Tiwari. "Revolutionizing Cancer Treatment: The Promising Potential of Nanotherapeutics." Journal of Neonatal Surgery 14, no. 25S (2025): 994–1010. https://doi.org/10.63682/jns.v14i25s.6209.

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Nanotherapeutics has transformed cancer treatment by providing drug molecules at the sites of action with reduced systemic toxicity and maximum therapeutic efficacy. This review gives an overview of recent advancements in nanomedicine such as liposomes, polymeric nanoparticles, dendrimers, and metallic nanoparticles that provide targeted tumor targeting by passive and active means. The nanocarriers achieve maximum bioavailability, achieve controlled drug release, and improve patient outcome. Besides, nanotechnology has also been incorporated into biomedical imaging, immunotherapy, and artifici
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Dasgupta, Rajarshi, Akash Bhargaw, Amaresh Hadimani, Meghana G. B., Mahesh G. Shetty, and S. K. Ghosh. "Zn Check: Revolutionizing Plant Nutrition with Amino Acid-based Zinc Chelation." Asian Journal of Soil Science and Plant Nutrition 10, no. 2 (2024): 301–10. http://dx.doi.org/10.9734/ajsspn/2024/v10i2287.

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Zinc plays a vital role in plant growth and development, impacting essential physiological processes such as cell division, nitrogen, carbohydrate metabolism and chloroplast development. However, zinc deficiency poses a significant challenge in agriculture, particularly in crops grown on calcareous soils. Traditional zinc fertilizers, like Zn EDTA, face limitations in alkaline soils, prompting the need for innovative solutions. This study introduces an amino acid-based chelating agent, Zinc Check, synthesized to address these challenges effectively. The research demonstrates the stability and
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Wei, Ziran. "mRNA cancer vaccines: revolutionizing personalized immunotherapy: progress, challenges, and future directions." Theoretical and Natural Science 74, no. 1 (2024): 86–92. https://doi.org/10.54254/2753-8818/2024.la18939.

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mRNA cancer vaccines represent a promising advancement in cancer immunotherapy, offering a personalized approach to treatment. This review explores the current state, challenges, and future directions of mRNA cancer vaccine development. Despite the global burden of cancer, traditional treatments often face limitations in efficacy and side effects. mRNA vaccines address these issues by stimulating targeted immune responses against cancer-specific antigens. Clinical trials have demonstrated their safety and tolerability, with most side effects being mild to moderate and transient. However, chall
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Arunkumar, Paramasivan. "Revolutionizing Credit Risk Assessment AI in Card Transaction Analytics." INTERNATIONAL JOURNAL OF INNOVATIVE RESEARCH AND CREATIVE TECHNOLOGY 6, no. 1 (2020): 1–9. https://doi.org/10.5281/zenodo.14551643.

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This Article examines the transformative impact of artificial intelligence (AI) on credit risk assessment within card transaction analytics. By harnessing AI's advanced capabilities in data analysis and pattern recognition, financial institutions can now conduct more nuanced and accurate evaluations of an individual&rsquo;s creditworthiness, identify potential defaults, and detect early signs of financial distress in real time. Traditional credit scoring models, previously limited by static data and periodic assessments, are significantly enhanced by AI&rsquo;s ability to analyze vast transact
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Singh, Romi, Priya Arya, and Shwetank H. Dubey. "Artificial Intelligence in Pharmaceutics: Revolutionizing Drug Formulation and Optimization." Journal of Drug Discovery and Health Sciences 1, no. 03 (2024): 138–45. https://doi.org/10.21590/jddhs.01.03.03.

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Artificial intelligence (AI) is revolutionizing the pharmaceutical industry, particularly in drug formulation and optimization. This article explores the multifaceted role of AI across various stages of drug development, from discovery and preclinical trials to clinical trials and manufacturing. AI enhances the efficiency, precision, and personalization of drug development, improving formulation design, stability, and bioavailability. The integration of AI with other emerging technologies, such as blockchain and the Internet of Things (IoT), is poised to further advance the industry by ensurin
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Santhi Swarup Manugula, Dubiwak Nemera Hanbisa, and Bulcha Assefa Diba. "Revolutionizing roads: Exploring crumble rubber and sisal fibers for sustainable asphalt solutions." World Journal of Advanced Research and Reviews 22, no. 2 (2024): 1865–80. http://dx.doi.org/10.30574/wjarr.2024.22.2.1574.

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This research aims to investigate the stability of asphalt mixtures using crumble rubber and sisal fiber mixes. Common laboratory tests were performed on the modified bitumen asphalt mix using various proportions of CR-SF and thus analyzed. The Marshal Mix design procedure was used to determine the Optimum Bitumen Content (OBC) and test the modified mixture properties. Hot Mix Asphalt (HMA) is a particulate composite material consisting of mineral aggregates, asphalt binder, and air voids. Asphalt binder is considered the most expensive and economically variable material. The increase in energ
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Santhi, Swarup Manugula, Nemera Hanbisa Dubiwak, and Assefa Diba Bulcha. "Revolutionizing roads: Exploring crumble rubber and sisal fibers for sustainable asphalt solutions." World Journal of Advanced Research and Reviews 22, no. 2 (2024): 1865–80. https://doi.org/10.5281/zenodo.14709958.

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This research aims to investigate the stability of asphalt mixtures using crumble rubber and sisal fiber mixes. Common laboratory tests were performed on the modified bitumen asphalt mix using various proportions of CR-SF and thus analyzed. The Marshal Mix design procedure was used to determine the Optimum Bitumen Content (OBC) and test the modified mixture properties. Hot Mix Asphalt (HMA) is a particulate composite material consisting of mineral aggregates, asphalt binder, and air voids. Asphalt binder is considered the most expensive and economically variable material. The increase in energ
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Maithili, Kamble Dr. Shivappa Nagoba* Avinash Swami Nivrutti Kotsulwar Mayur Upade Amrapali Rajput. "Review On Artificial Intelligence Revolutionizing the Pharmaceutical Industry." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2028–43. https://doi.org/10.5281/zenodo.15393564.

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Artificial Intelligence (AI) and Machine Learning (ML) are revolutionizing the pharmaceutical industry, driving advancements across drug discovery, formulation, manufacturing, and clinical trials. AI tools such as molecular visualization software, predictive algorithms like Random Forest, and Principal Component Analysis (PCA) are pivotal in assessing drug stability and designing stable drug-polymer systems, which are essential for developing solid dispersions. Artificial Neural Networks (ANNs) have demonstrated superior accuracy in predicting the crystalline and amorphous content of drugs com
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Wang, Huining. "AI-Driven Financial Reporting and Risk Management: A Path to Economic Growth and Market Efficiency." Academic Journal of Sociology and Management 2, no. 5 (2024): 32–37. https://doi.org/10.5281/zenodo.13765776.

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Recent advances in Artificial Intelligence (AI) are having a tremendous effect on the financial industry, particularly in areas of reporting and risk management. Literature research makes it evident that artificial intelligence technologies are revolutionizing how financial information is collected, analyzed and disseminated to enhance accuracy and decision-making processes. In this paper we investigate AIs transformative role in financial reporting and risk management. This paper addresses how AI may assist the U.S. economy by improving efficiency, accuracy and economic stability. Furthermore
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Ankita., S. Kshirsagar*1 Tushar Rode2 Anil. V. Chandewar3 Ishwari. R. Chaudhari4. "REVOLUTIONIZING HERBAL THERAPEUTICS: EXPLORING ADVANCED NANOTECHNOLOGY DRUG DELIVERY SYSTEM (NDDS)." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 628–53. https://doi.org/10.5281/zenodo.10836866.

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Nanotechnology has revolutionized various fields, including drug delivery systems. In recent years, there has been a growing interest in utilizing nanotechnology to enhance the efficacy and delivery of herbal drugs. This review explores the applications of nanotechnology in herbal drug technology, focusing on the strategies employed to improve solubility, bioavailability, stability, and targeted delivery of herbal bioactives. Various nanoformulations such as nanoparticles, liposomes, micelles, and nanoemulsions have been developed to overcome the limitations associated with traditional herbal
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Fatima, Munazza, Timothy An, and Kee-Jong Hong. "Revolutionizing mRNA Vaccines Through Innovative Formulation and Delivery Strategies." Biomolecules 15, no. 3 (2025): 359. https://doi.org/10.3390/biom15030359.

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Modernization of existing methods for the delivery of mRNA is vital in advanced therapeutics. Traditionally, mRNA has faced obstacles of poor stability due to enzymatic degradation. This work examines cutting-edge formulation and emerging techniques for safer delivery of mRNA vaccines. Inspired by the success of lipid nanoparticles (LNP) in delivering mRNA vaccines for COVID-19, a variety of other formulations have been developed to deliver mRNA vaccines for diverse infections. The meritorious features of nanoparticle-based mRNA delivery strategies, including LNP, polymeric, dendrimers, polysa
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Vinodkumar Devarajan. "Revolutionizing Energy Management: The Impact of AI and Machine Learning Technologies." Journal of Computer Science and Technology Studies 7, no. 3 (2025): 327–33. https://doi.org/10.32996/jcsts.2025.7.3.37.

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The integration of Artificial Intelligence and Machine Learning technologies is revolutionizing the energy sector by transforming energy optimization, predictive maintenance, and smart grid management. From advanced demand forecasting to dynamic pricing mechanisms, these technologies enable sophisticated control and monitoring of power distribution networks. The implementation of predictive maintenance systems with sensor analytics and anomaly detection frameworks has enhanced equipment reliability and operational efficiency. Smart grid management through AI-driven optimization and edge comput
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Oladapo, Bankole I., Mattew A. Olawumi, and Francis T. Omigbodun. "Revolutionizing Battery Longevity by Optimising Magnesium Alloy Anodes Performance." Batteries 10, no. 11 (2024): 383. http://dx.doi.org/10.3390/batteries10110383.

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This research explores the enhancement of electrochemical performance in magnesium batteries by optimising magnesium alloy anodes, explicitly focusing on Mg-Al and Mg-Ag alloys. The study’s objective was to determine the impact of alloy composition on anode voltage stability and overall battery efficiency, particularly under extended cycling conditions. The research assessed the anodes’ voltage behaviour and internal resistance across magnesium bis(trifluoromethanesulfonyl)imide (Mg(TFSI)2) electrolyte formulations using a systematic setup involving cyclic voltammetry on the anode and electroc
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Siti Khadijah Padzil, Mohd Faiz Abd Ghani, and Nur Saadiah Bt Badroll Hisham. "Revolutionizing Handmade Soap: Innovating Emollient Formulations for Enhanced Quality." Malaysia Journal of Invention and Innovation 3, no. 5 (2024): 51–55. https://doi.org/10.64382/mjii.v3i5.129.

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The widespread use of commercial soaps containing potentially harmful chemicals like parabens, sulphates, and triclosan has prompted concerns about skin health and overall well-being. This research addresses this issue by proposing a revolutionary approach to handmade soap formulations, focusing on enhancing quality through the incorporation of emollients. Handmade soaps, crafted from natural ingredients, offer a safer alternative to mass-produced varieties, potentially reducing skin irritation and allergic reactions. By utilizing emollients such as cocoa butter, shea butter, and mango butter,
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Das, Sanjoy, and Taison Jamatia. "NanoPhytoformulations: what is so interesting about the nanoscale ?" Sciences of Phytochemistry 1, no. 2 (2022): 34–36. http://dx.doi.org/10.58920/sciphy01020034.

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Nanotechnology is on the threshold of providing a host of new materials and approaches in revolutionizing the medical and pharmaceutical fields. The incorporation of nanotechnology in herbal formulation investigation has a huge number of benefits for phytomedicine such as enhancement of solubility and bioavailability, reinforcement of pharmacological activity, improvement of stability, protection from toxicity, sustained delivery, and safeguarding from physical or chemical degradation. This opinion paper briefly highlights the authors perspective on herbal nanotechnology through few key points
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Patel, Pawan, Jitendra Singh Chaudhary, Anubhav Dubey, and Gyan Singh. "Revolutionizing Dermatology with Precision Delivery of Tazarotene via Nanogel Systems." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 03 (2024): 1678–86. http://dx.doi.org/10.25258/ijpqa.15.3.89.

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The field of dermatology is being revolutionized with the introduction of precision delivery strategies, especially nanogels, which are improving the therapeutic potential of dermatological interventions. The present review has been compiled to elaborate on the remarkable potential of nanogel systems in targeting tazarotene, a retinoid that is deeply and widely utilized for treating several skin ailments such as acne, psoriasis, and photoaging. Given their outstanding priority, nano gels have attracted significant attention due to their distinct extent characteristics, including high biocompat
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Son, Ahrum, Jongham Park, Woojin Kim, et al. "Revolutionizing Molecular Design for Innovative Therapeutic Applications through Artificial Intelligence." Molecules 29, no. 19 (2024): 4626. http://dx.doi.org/10.3390/molecules29194626.

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The field of computational protein engineering has been transformed by recent advancements in machine learning, artificial intelligence, and molecular modeling, enabling the design of proteins with unprecedented precision and functionality. Computational methods now play a crucial role in enhancing the stability, activity, and specificity of proteins for diverse applications in biotechnology and medicine. Techniques such as deep learning, reinforcement learning, and transfer learning have dramatically improved protein structure prediction, optimization of binding affinities, and enzyme design.
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Guzmán-Sastoque, Paula, Cristian F. Rodríguez, María Camila Monsalve, et al. "Nanotheranostics Revolutionizing Gene Therapy: Emerging Applications in Gene Delivery Enhancement." Journal of Nanotheranostics 6, no. 2 (2025): 10. https://doi.org/10.3390/jnt6020010.

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Nanotheranostics—where nanoscale materials serve both diagnostic and therapeutic functions—are rapidly transforming gene therapy by tackling critical delivery challenges. This review explores the design and engineering of various nanoparticle systems (lipid-based, polymeric, inorganic, and hybrid) to enhance stability, targeting, and endosomal escape of genetic payloads. We discuss how real-time imaging capabilities integrated into these platforms enable precise localization and controlled release of genes, improving treatment efficacy while reducing off-target effects. Key strategies to overc
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Zannou, Oscar, Kouame F. Oussou, Ifagbémi B. Chabi, et al. "Nanoencapsulation of Cyanidin 3-O-Glucoside: Purpose, Technique, Bioavailability, and Stability." Nanomaterials 13, no. 3 (2023): 617. http://dx.doi.org/10.3390/nano13030617.

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The current growing attractiveness of natural dyes around the world is a consequence of the increasing rejection of synthetic dyes whose use is increasingly criticized. The great interest in natural pigments from herbal origin such as cyanidin 3-O-glucoside (C3G) is due to their biological properties and their health benefits. However, the chemical instability of C3G during processing and storage and its low bioavailability limits its food application. Nanoencapsulation technology using appropriate nanocarriers is revolutionizing the use of anthocyanin, including C3G. Owing to the chemical sta
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Gupta, Pramod K., and James R. Siegenthaler. "Revolutionizing Electrochemical Sensing with Nanomaterial-Modified Boron-Doped Diamond Electrodes." Chemosensors 13, no. 5 (2025): 183. https://doi.org/10.3390/chemosensors13050183.

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Nanomaterial advancements have heralded a new era in electrochemical sensing by enabling the precise modification of boron-doped diamond (BDD) electrodes. This review investigates recent remarkable advances, challenges, and potential future directions of nanomaterial-modified BDD electrodes for biosensing applications, emphasizing their game-changing potential. This review begins by investigating the intrinsic properties of boron-doped diamond electrodes, emphasizing their inherent advantages in electrochemical biosensing. Following that, it embarks on an illuminating journey through the spect
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Sinicin, Alexey M. "EXPLORATION OF OXIDE SEMICONDUCTOR BASED TRANSPARENT ELECTRONICS." EKONOMIKA I UPRAVLENIE: PROBLEMY, RESHENIYA 9/7, no. 150 (2024): 130–38. http://dx.doi.org/10.36871/ek.up.p.r.2024.09.07.016.

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Oxide semiconductor-based transparent electronics represents a promising direction capable of revolutionizing the field of modern devices. This article reviews key materials including ZnO and IGZO, their structural and optical properties, and their impact on the performance of thin-film transistors. Major challenges such as stability and manufacturing difficulties are discussed, as well as prospects for the use of new materials. The article highlights the importance of integrating transparent electronics with traditional technologies and its potential for wide applications in various industrie
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Lyu, Xiang, and Alexey Serov. "Revolution of Electrode Design Toward Oxygen Evolution Reaction for Anion Exchange Membrane Water Electrolysis." ECS Meeting Abstracts MA2024-01, no. 34 (2024): 1712. http://dx.doi.org/10.1149/ma2024-01341712mtgabs.

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Anion exchange membrane water electrolyzer (AEMWE) is a promising next-generation technology for producing green hydrogen coupling with cost-effective, platinum group metal-free (PGM-free) catalysts. In AEMWE, oxygen evolution reaction (OER) at the anode plays a more vital role compared with the cathodic reaction of hydrogen evolution reaction (HER). While tremendous attention has been devoted to enhancing the activity of OER catalysts, the long-term stability and cost of OER catalysts, which may play an even more important role in large-scale electrolysis industrialization, have been much les
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Zhang, Ruiquan, Zhou Zhang, Qing Chen, Maocong Hu, and Zhenhua Yao. "Revolutionizing Fuel Cell Efficiency with Non-Metallic Catalysts for Oxygen Reduction Reactions." Global Environmental Engineers 9 (December 25, 2022): 49–59. http://dx.doi.org/10.15377/2410-3624.2022.09.4.

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Platinum-based catalysts are widely used in oxygen reduction reactions, but platinum’s high cost and low reserves have restricted their sustainable development. With continuous in-depth research, it has been found that metal-free catalysts also have better catalytic activity in oxygen reduction reactions and have great potential for development due to the low cost and abundant reserves of metal-free catalysts, which has become a hot research direction. This paper reviews the application of metal-free catalysts in oxygen reduction reactions, including heteroatom-doped carbon-based catalysts, po
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Saket, Kumar, Parvez Alam, and Anamika Jha. "Revolutionizing Frontal Bone Fracture Stability: Extracorporeal Fixation with Fibrin Sealant as a Benchmark in Management." Karnataka Journal of Surgery 2 (July 9, 2025): 70–75. https://doi.org/10.25259/kjs_21_2024.

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Frontal bone fractures, although relatively rare in maxillofacial trauma, present unique challenges due to risks of cerebrospinal fluid (CSF) leaks, sinus infections, and facial deformities. Effective management is essential to protect intracranial structures, prevent sinus complications, and restore an aesthetic contour. This case report describes a 24-year-old male with a depressed frontal bone fracture involving both the anterior and posterior tables, as well as CSF rhinorrhea, successfully managed with extracorporeal fixation and fibrin sealant. The surgical approach utilised a bicoronal i
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Wang, Ruirui. "From Lab to Shelf: Gelatin-Based pH Sensors Revolutionizing Food Packaging." Gels 11, no. 5 (2025): 327. https://doi.org/10.3390/gels11050327.

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The development of multifunctional smart food packaging has garnered considerable attention in research. Gelatin exhibits outstanding characteristics, featuring remarkable gel strength, molecular binding affinity, excellent colloidal dispersibility, low solution viscosity, sustained dispersion stability, and significant water retention properties. Gelatin-based film is ideally suited for the developing simple, portable, and rapid pH sensors, owing to its satisfactory biocompatibility, biodegradability, biosafety, affordability, and facilitation of easy handling and usage. This paper aims to ex
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Kolawole, Michael Ibukun, and Busayo Leah Ayodele. "A Review of Solid-State Battery for Advancement in Energy Storage." International Journal of Research and Innovation in Applied Science X, no. VI (2025): 914–25. https://doi.org/10.51584/ijrias.2025.10060068.

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This paper provides a comprehensive review of Solid-State Batteries (SSBs), a transformative energy storage technology poised to surpass conventional lithium-ion batteries. SSBs utilize solid electrolytes in place of flammable liquid or gel-based electrolytes, leading to improvements in safety, energy density, lifecycle, and thermal stability. The study explores the key components of SSBs, including advanced solid electrolytes such as garnet-type LLZO, and evaluates various synthesis methods like sol-gel, spark plasma sintering, and electrospinning. While SSBs show immense potential, challenge
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Shrotriya, Juliyas. "Nanogels in Herbal Medicine: Revolutionizing Drug Delivery for Enhanced Arthritis Treatment." Journal of Pharmaceutical Research International 36, no. 7 (2024): 32–38. http://dx.doi.org/10.9734/jpri/2024/v36i77536.

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In terms of stability and quick reaction to external stimuli, nanogels are highly fa-voured materials in herbal medicine. In order to provide herbal products with greater cellular penetration than currently possible, nanogel is proving to be a novel approach to oral and transdermal medicine delivery for a number of untreated ailments, includ-ing. Inflammation of one or more joints causes pain and stiffness that can worsen with age. Different types of arthritis exist, each with different causes including wear and tear, infections and underlying diseases. Symptoms include pain, swelling, reduced
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Kamal, Singh Rathore Jain Monal*. "Nanocarriers Revolutionizing Transdermal Drug Delivery: A Comprehensive Review of Recent Advances." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 1753–65. https://doi.org/10.5281/zenodo.12806579.

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Nanocarrier-based transdermal drug delivery systems (TDDS) represent cutting-edge innovations in delivery methods, offering enhanced drug penetration through the skin, which serves as a significant barrier in traditional TDDS. This review aims to offer a comprehensive analysis of nanocarrier-based transdermal drug delivery systems (TDDS), focusing on their mechanisms, types, advantages, challenges, and future prospects. The primary objective is to highlight the key benefits of these systems, including improved drug permeability, controlled and sustained release, targeted delivery, reduced syst
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Papadimitriou, Vasileios A., Evgenyia Pechnikova, Merijn Pen, and Hector Hugo Perez Garza. "BPS2025 - Silicon-based cryo-EM grids: Revolutionizing sample stability and data quality with microfabrication and graphene." Biophysical Journal 124, no. 3 (2025): 312a—313a. https://doi.org/10.1016/j.bpj.2024.11.1734.

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Jang, Eunbin, Seungjin Park, Jemin Lee, Patrick Joohyun Kim, and Jeeyoung Yoo. "Revolutionizing anode-free batteries with holey graphene interlayers: Achieving uniform lithium deposition and long-term stability." Journal of Energy Storage 115 (April 2025): 115974. https://doi.org/10.1016/j.est.2025.115974.

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M, Umaselvi, S. Leena Maria, Sridevi M.J., Gayathri B, and Khaled A. A. Alloush. "REVOLUTIONIZING VANETS WITH GRAPH NEURAL NETWORKS USING DYNAMIC TRAFFIC MANAGEMENT." ICTACT Journal on Communication Technology 15, no. 2 (2024): 3217–22. http://dx.doi.org/10.21917/ijct.2024.0479.

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The increasing movement from rural areas to urban areas, along with the widening gap in population, has resulted in metropolitan areas becoming extremely overpopulated. As a result of the high volume of traffic that occurs in these areas, traffic monitoring is an extremely important activity. According to the findings of this study, an improved authentication and communication protocol that is based on clusters could be implemented for Intelligent Transportation Systems in Vehicular Ad Hoc Networks (VANETs). Our number one objective is to enhance the sharing of resources amongst vehicles throu
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Singh, Pratik, Denish Gandhi, Ajay Khopade, et al. "Recent Advancement in Capsule: Emerging Novel Technologies and Alternative Shell Materials for Wide Range of Therapeutic Needs." Journal of Ravishankar University (PART-B) 37, no. 2 (2024): 128–55. https://doi.org/10.52228/jrub.2024-37-2-10.

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Advancements in capsule technology are revolutionizing drug delivery by enhancing therapeutic efficacy, patient compliance, and precision medicine. This review examines innovative capsule systems, including the Novel Floating Ring Capsule for extended gastric retention, Telemetric Capsules for real-time health monitoring, and CODAS for circadian rhythm-based drug release. Technologies such as Innercap's capsule-in-capsule design, SODAS® and DUOCAP® for controlled and sustained release, and hydrogel-based and hydrophilic sandwich capsules for targeted delivery are discussed. These cutting-edge
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Häusler, Michael, Olga Stamati, Julie Villanova, et al. "Multimethod Approach to Uncover the Capacity Loss in Silicon-Based Lithium-Ion Batteries." Microscopy & Microanalysis 30, Supplement 1 (2024): 258–59. https://doi.org/10.1093/mam/ozae044.116.

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The surge in electrification, driven by the increasing prominence of electric vehicles, renewable energy storage, and portable electronics, has propelled lithium-ion batteries (LIBs) into the forefront of energy storage technologies. However, the relentless pursuit of electrification demands continuous improvements in energy densities, cycling stability, and overall endurance for the next generation of Li-ion batteries. A promising avenue for revolutionizing energy storage lies in the integration of silicon (Si) with a high weight percentage into LIB anodes, offering not only an impressive the
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Zhao, Ming, Zhiguo Xia, Xiaoxiao Huang, et al. "Li substituent tuning of LED phosphors with enhanced efficiency, tunable photoluminescence, and improved thermal stability." Science Advances 5, no. 1 (2019): eaav0363. http://dx.doi.org/10.1126/sciadv.aav0363.

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Solid-state phosphor-converted white light-emitting diodes (pc-WLEDs) are currently revolutionizing the lighting industry. To advance the technology, phosphors with high efficiency, tunable photoluminescence, and high thermal stability are required. Here, we demonstrate that a simple lithium incorporation in NaAlSiO4:Eu system enables the simultaneous fulfillment of the three criteria. The Li substitution at Al sites beside Na sites in NaAlSiO4:Eu leads to an enhanced emission intensity/efficiency owing to an effective Eu3+to Eu2+reduction, an emission color tuning from yellow to green by tuni
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Harsh, Lad Ankit Rohit Durgesh Singh* Ujjwal Sharma Hinal Patel Heeya Sheth. "Revolutionizing Skincare: The Role of Nano Particle in Various Skincare Treatment." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 2450–69. https://doi.org/10.5281/zenodo.14768929.

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Nanoparticles are quickly becoming recognized as a ground-breaking invention in the skincare industry, with their extraordinary potential for precise and efficient treatments. Nanoparticles can transport active chemicals more effectively because of their minuscule size, which usually ranges from 1 to 100 nanometres. This allows them to pierce deeper into the skin's layers. By guaranteeing that active ingredients get to the precise locations where they are most required, this technique allows for more targeted treatment of a range of skin disorders, including Breakouts, Hyperpigmentation and ag
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Dangeti, Appalaraju, Deekshi Gladiola Bynagari, and Krishnaveni Vydani. "Revolutionizing Drug Formulation: Harnessing Artificial Intelligence and Machine Learning for Enhanced Stability, Formulation Optimization, and Accelerated Development." International Journal of Pharmaceutical Sciences and Medicine 8, no. 8 (2023): 18–29. http://dx.doi.org/10.47760/ijpsm.2023.v08i08.003.

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The integration of Artificial Intelligence (AI) and Machine Learning (ML) in the field of pharmaceutical drug formulation has sparked a paradigm shift in the way drug stability is predicted, formulations are optimized, and drug development is expedited. This review delves into the transformative impact of AI and ML techniques on pharmaceutical research and development. It highlights how predictive models driven by AI algorithms are effectively simulating drug degradation pathways and stability profiles, enabling scientists to make informed decisions during formulation design. Moreover, the uti
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