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Dissertations / Theses on the topic 'Rfc1'

Author: Grafiati

Published: 7 July 2024

Last updated: 31 July 2025

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1

Breitenbücher, Frank. "Allgemeine und funktionelle Untersuchungen zur grossen Untereinheit des humanen Replikationsfaktors C (RFC1), sowie initiale Untersuchungen zur Regulation der Expression von RFC1 durch das BCR-ABLp210-Onkogen." [S.l.] : [s.n.], 2005. http://archiv.ub.uni-marburg.de/diss/z2005/0114/.

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Hinken, Matthias. "Gewebeverteilung und Lokalisation des Transportproteins für reduzierte Folate (RFC1) der Ratte." Doctoral thesis, Universitätsbibliothek Leipzig, 2007. http://nbn-resolving.de/urn:nbn:de:bsz:15-20071107-143055-8.

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Der Folsäureantagonist Methotrexat (MTX) wird zur Behandlung onkologischer und rheumatoider Erkrankungen eingesetzt. Die Aufnahme des Methotrexats in die Zielzelle ist dabei Vorraussetzung für die Bindung an seine intrazellulären Zielstrukturen und erfolgt über verschiedene Transportsysteme. In diesem Zusammenhang ist bei entsprechenden Plasma-konzentrationen von MTX der Reduced Folate Carrier (RFC1) von besonderer Bedeutung. 1994 konnte erstmals die cDNA dieses Transporters aus Maus- und Hamstergewebe isoliert werden. Die cDNA für einen mit dem RFC1 identischen hepatozellulären MTX-Transporte

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3

Chazelas, Pauline. "Syndrome de CANVAS – Analyse moléculaire des répétitions pentanucléotidiques du gène RFC1 et étude de leurs conséquences physiopathologiques." Electronic Thesis or Diss., Limoges, 2024. http://www.theses.fr/2024LIMO0006.

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Le syndrome de CANVAS définie un ensemble d’entités cliniques que sont l’ataxie cérébelleuse, la neuronopathie sensitive et l’aréflexie vestibulaire, responsable conjointement ou individuellement de différents symptômes dont le plus majoritaire est un trouble de l’équilibre. De façon intéressante, il est maintenant établi que la majorité des patients présentent, des dizaines d’années avant les troubles neurologiques, une toux chronique réfractaire. En 2019, la cause génétique de ce syndrome a été décrite. Elle intéresse le gène RFC1 au sein duquel une expansion biallélique de répétitions du pe

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4

Halwachs, Sandra. "Regulation des Reduced Folate Carrier (RFC1) in HPCT-1E3-Ratten-Hepatocytoma-Zellen durch Cytochrom P450-Induktoren vom Phenobarbital-Typ." Doctoral thesis, Universitätsbibliothek Leipzig, 2006. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-34397.

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The sodium dependent reduced folate carrier (Rfc1; Slc19a1) provides the major route for cellular uptake of antifolate chemotherapeutic drugs such as methotrexate (MTX) and reduced folates into liver, kidneys and other tissues. Despite its essential role in cancer treatment and for the body’s folate homeostasis, little is known about Rfc1 regulation. In rat hepatocytes, the 5´ untranslated region of this carrier exhibits, amongst other regulatory elements, a barbiturate recognition box which as yet has only been found in the promotor region of xenobiotic metabolizing enzymes, particularly thos

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Lopes, Tairine Zara. "Avaliação de polimorfismos nos genes MTHFR, MTR, RFC1 e CßS envolvidos no metabolismo do folato em pacientes com câncer de tireoide." Faculdade de Medicina de São José do Rio Preto, 2015. http://hdl.handle.net/tede/272.

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Submitted by Fabíola Silva (fabiola.silva@famerp.br) on 2016-06-21T19:17:07Z No. of bitstreams: 1 tairinezaralopes_dissert.pdf: 1511634 bytes, checksum: 2203122e0b39cf1687115059c3e19447 (MD5)<br>Made available in DSpace on 2016-06-21T19:17:07Z (GMT). No. of bitstreams: 1 tairinezaralopes_dissert.pdf: 1511634 bytes, checksum: 2203122e0b39cf1687115059c3e19447 (MD5) Previous issue date: 2015-10-29<br>Introduction: Thyroid cancer is the most common malignancy of the endocrine system and has been presenting continuous increase in the last years. Studies suggest that folate deficiency in the

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Tomida, Junya. "DNA damage induced ubiquitylation of RFC2 subunit of RFC complex." Kyoto University, 2008. http://hdl.handle.net/2433/135870.

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Ng, Chin Chin. "Performance analysis of the mobile IP protocol (RFC 3344 and related RFCS)." Thesis, Monterey, Calif. : Naval Postgraduate School, 2006. http://bosun.nps.edu/uhtbin/hyperion.exe/06Dec%5FNg%5FChin.pdf.

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Thesis (M.S. in Computer Science)--Naval Postgraduate School, December 2006.<br>Thesis Advisor(s): George W. Dinolt, J. D. Fulp. "December 2006." Includes bibliographical references (p. 121-125). Also available in print.

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Hakim, Chantal DDS MSD, Marie M. MD PhD DrSc Tolarová, and Miroslav MD PhD Tolar. "Association of Type and Severity of Nonsyndromic Orofacial Clefts with Combined Genotypes of RFC1 80 GA, MTHFR 677 CT, IRF6 (rs642961) and IRF6 (rs2235371) Gene Polymorphisms in an Indian Population." Scholarly Commons, 2020. https://scholarlycommons.pacific.edu/dugoni_etd/2.

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Association of type and severity of nonsyndromic OROFACIAL CLEFTS with combined genotypes of RFC1 80 GA, MTHFR 677 CT, IRF6 rs642961 and rs2235371 gene polymorphisms in an Indian population Abstract By Chantal Hakim University of the Pacific. Arthur Dugoni School of Dentistry 2020 Introduction. Genetic etiology of nonsyndromic orofacial clefts comprises many genes acting together. However, little is known about their interactions. The purpose of our study was to analyze associations of phenotypic subtypes of nonsyndromic orofacial clefts with combinations of four genotypes involvi

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Giusti, Kelma Cordeiro da Silva. "Associação entre polimorfismos em genes relacionados ao metabolismo de folato (RFC1, GCP2, MTHFR e MTHFD1) e alterações nas concentrações de folato, cobalamina e homocisteína em mulheres com história de abortos espontâneos recorrentes." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-08032013-115754/.

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O aborto espontâneo recorrente (AER) é caracterizado pela ocorrência de três ou mais abortos consecutivos e acomete 2-4% das mulheres em idade fértil. A etiologia está associada a vários fatores de risco, tais como anomalias uterinas, aberrações cromossômicas, autoimunidade, trombofilias, elevação na concentração de homocisteína (tHcy), porém cerca de 40% dos casos permanece sem causa definida. O metabolismo de unidades de carbono desempenha papel fundamental na disponibilidade de folato na célula, sendo essencial para o desenvolvimento placentário e fetal. Deficiência de vitaminas que regulam

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Alata, Jimenez Nagif. "La deficiencia en los transportadores de folato (FOLR1 y RFC1) causa cambios epigenéticos que afectan el desarrollo neural y de las células de la cresta neural en embriones de pollo Gallus gallus." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2019. https://hdl.handle.net/20.500.12672/10342.

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El desarrollo neural ocurre mediante el proceso de neurulación originando el sistema nervioso central y la médula espinal. Durante este proceso las células de la cresta neural (CCN) son especificadas en la región más dorsal del tubo neural; posteriormente, las CCN delaminan del epitelio neural, migran a diferentes regiones del embrión y se diferencian en diversos tipos celulares. Defectos en el desarrollo del tubo neural y de las CCN generan desórdenes congénitos como espina bífida, encefalocelia, y neurocristopatías (paladar-labio hendido, albinismo, entre otras). Una vitamina importante dura

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Kim, Jiyoung. "Functional analysis of RFC and RFC-like complexes in fission yeast." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/12375.

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RFC plays an essential role in DNA replication by loading the sliding clamp PCNA onto DNA in order to tether DNA polymerase δ to DNA. RFC consists of five subunits, one large subunit and four small subunits. The large subunit of RFC contains an extended C-terminal domain that is not present in the small subunits and whose function remains unknown. In addition to RFC, eukaryotic cells contain two more putative PCNA loaders known as RLCs. These other PCNA loaders have similar structures to RFC and contains the RFC small subunits, however the large subunit is replaced with a different protein, e

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Silva, Alan Castro. "Implementação inicial da RFC 6897." Universidade Federal de São Carlos, 2016. https://repositorio.ufscar.br/handle/ufscar/8806.

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Submitted by Milena Rubi (milenarubi@ufscar.br) on 2017-06-01T14:58:47Z No. of bitstreams: 1 SILVA_Alan_2016.pdf: 14722594 bytes, checksum: 0c8346924c434318f6c349f7ed8112d9 (MD5)<br>Approved for entry into archive by Milena Rubi (milenarubi@ufscar.br) on 2017-06-01T14:58:54Z (GMT) No. of bitstreams: 1 SILVA_Alan_2016.pdf: 14722594 bytes, checksum: 0c8346924c434318f6c349f7ed8112d9 (MD5)<br>Approved for entry into archive by Milena Rubi (milenarubi@ufscar.br) on 2017-06-01T14:58:59Z (GMT) No. of bitstreams: 1 SILVA_Alan_2016.pdf: 14722594 bytes, checksum: 0c8346924c434318f6c349f7ed8112d9 (MD

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Mankelow, Rowena Chemistry Faculty of Science UNSW. "Creating mesophorous materials by liquid crystal templating of readily available materials." Awarded by:University of New South Wales, 2003. http://handle.unsw.edu.au/1959.4/38346.

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Zhao, Min Chemistry Faculty of Science UNSW. "A fill and flow channel enzyme biosensor." Awarded by:University of New South Wales, 2004. http://handle.unsw.edu.au/1959.4/38333.

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Perez-Bercoff, Danielle. "L'activation des macrophages via les RFcγ inhibe la réplication du VIH-1". Paris 7, 2002. http://www.theses.fr/2002PA077144.

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Siberil, Sophie. "Etude des interactions moléculaires entre RFcγ et IgG : implications fonctionnelles et thérapeutiques". Paris 6, 2005. http://www.theses.fr/2005PA066549.

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Bruhns, Pierre. "Bases moleculaires des proprietes inhibitrices des rfc ii b." Paris 6, 2001. http://www.theses.fr/2001PA066039.

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Les recepteurs de faible affinite pour la portion fc les igg (rfciib) regulent negativement la proliferation et l'activation de cellules du systeme immunitaire. Ces recepteurs inhibiteurs possedent un immunoreceptor tyrosine-based inhibition motif (itim) dans leur domaine intracytoplasmique qui, lorsqu'il est phosphoryle lors la coagregation des rfciib a des recepteurs activateurs, recrute les inositol 5-phosphatase a domaine sh2, ship1 et ship2. Comme la majorite des autres recepteurs a itim, les kir2dl3, des killer cell inhibitory receptors with a long intracytoplasmic domain capables d'inhi

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Bartoš, Patrik. "Testování přenosových parametrů internetového připojení." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-442361.

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This thesis deals with methodology for measuring transmission parameters of internet connection. The aim of the thesis is to cover and compare known methods used for testing. Based on the research then design and realize an application that will provide those kind of measurements.

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Watson, Joni. "Identification of Transcription Factors GZF3, RFX1, Orf19.3928 as Being Implicated in Candida-Bacterial Interactions." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/honors/261.

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Candida albicans is an opportunistic pathogen that is present in the normal flora in a majority of individuals. One key factor in C. albicans virulence is the ability to change its morphology from yeast to an elongated or hyphal form. The regulation of this morphogenesis relies in part upon quorum sensing (QS) molecules. C. albicans often exists as part of a mixed culture alongside other microbes and is influenced by their presence as well as the presence of QS molecules that they produce. In this study, a library of diploid homozygous transcriptional regulator knockout (TRKO) mutants were scr

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Schrader, Stephanie. "Molekularbiologische und zellbiologische Charakterisierung alternativer Splicing- Varianten des Methotrexat- Carriers (RFC)." Doctoral thesis, Universitätsbibliothek Leipzig, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:15-20090429-113312-2.

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Die Chemotherapie hat in letzten Jahren in der Veterinärmedizin zunehmend an Bedeutung gewonnen. Das Zytostatikum Methotrexat (MTX) wird in der Veterinärmedizin vorwiegend zur Behandlung von Lymphomen und lymphatischen Leukämien eingesetzt. In der Humanmedizin findet es aufgrund seiner immunsuppressiven Wirkung auch bei nicht neoplastischen Erkrankungen wie der rheumatoiden Arthritis Anwendung. Die Aufnahme von reduzierten Folaten und MTX wird vornehmlich als aktiver Transport über den Reduced folate carrier (Rfc) vermittelt. Inzwischen konnte die für das Transportprotein codierende cDNA aus M

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Bossard, Florian. "La mucoviscidose : correction de la mutation [delta]F508 par sur-expression de NHE-RF1 : modifications d'expression de NHE-RF1 et des récepteurs [béta]-adrénergiques dans les poumons humains." Nantes, 2007. http://archive.bu.univ-nantes.fr/pollux/show.action?id=6c13703c-0312-4f63-9879-11bdd9fd3d9a.

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Ces travaux de thèse se sont organisés autour de deux projets. Premièrement, nous avons étudié l'impact d'une protéine partenaire de CFTR, NHE-RF1, sur la protéine mutée la plus fréquente dans la mucoviscidose : deltaF508. NHE-RF1 était décrite jusque là pour son implication dans l'adressage apical et la stabilité membranaire de la protéine CFTR sauvage. Nos travaux démontrent que la surexpression de NHE-RF1 corrige le défaut d'adressage de deltaF508 et restaure une activité partielle de canal chlorure. Deuxièmement, nous nous sommes intéressés à l'expression des récepteurs beta-adrénergiques

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Vehera, Vladyslav. "Přenosové technologie VDSL2 vplus a G.fast a jejich testování." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413049.

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This semester work focuses on the basic characteristics of the VDSl2 and G.fast technologies that allow to transfer data using old telephone lines. The theoretical part of the work describes the main parameters of all currently known profiles for VDSL and G.fast. There is also a description of DMT modulation, used in both types of DSL connections. Moreover, the theoretical part presents a vectoring technique that helps to increase the data transfer rate using a twisted pair. The work also provides methods for testing networks using the recommendations of RFC 2455, ITU-T Y.1564 and RFC6349. The

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Silva, Dênis [UNESP]. "Purificação e caracterização bioquímica de poligalacturonases produzidas pelo fungo Penicillium viridicatum RFC3 em fermentação em estado sólido e submersa." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/103949.

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Made available in DSpace on 2014-06-11T19:32:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-09-22Bitstream added on 2014-06-13T20:24:23Z : No. of bitstreams: 1 silva_d_dr_rcla.pdf: 1167994 bytes, checksum: eca15b5bfad71b8173fe9d808385fd94 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>A poligalacturonase (PG) é uma pectinase que degrada a molécula de pectina atuando internamente , ao acaso, liberando oligossacarídeos (Endo-PG) ou por ataque a partir da extremidade não redutora da cadeia, liberando moléculas de ácido galacturônico (Exo-PG). As pectinases,

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Silva, Dênis. "Purificação e caracterização bioquímica de poligalacturonases produzidas pelo fungo Penicillium viridicatum RFC3 em fermentação em estado sólido e submersa /." Rio Claro : [s.n.], 2006. http://hdl.handle.net/11449/103949.

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Orientador: Eleni Gomes<br>Banca: Eleonora Cano Carmona<br>Banca: Rubens Monti<br>Banca: Iracema de Oliveira Moraes<br>Banca: Márcia Luzia Rizzatto<br>Resumo: A poligalacturonase (PG) é uma pectinase que degrada a molécula de pectina atuando internamente, ao acaso, liberando oligossacarídeos (Endo-PG) ou por ataque a partir da extremidade não redutora da cadeia, liberando moléculas de ácido galacturônico (Exo-PG). As pectinases, como várias outras enzimas, têm sido obtidas a partir de microrganismos, em processos fermentativos em estado sólido (FES) e fermentação submersa (FSM). A purificação

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Walter, Aaron Joseph. "Approximate Thermal Modeling of Radiofrequency Cardiac Ablation." Diss., CLICK HERE for online access, 2005. http://contentdm.lib.byu.edu/ETD/image/etd1002.pdf.

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SILVA, Rafaela Maria Seabra. "Polimorfismos em genes envolvidos no metabolismo do ácido fólico e o risco de desenvolvimento da leucemia infantil." Universidade Federal de Pernambuco, 2010. https://repositorio.ufpe.br/handle/123456789/19894.

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Submitted by Luiza Maria Pereira de Oliveira (luiza.oliveira@ufpe.br) on 2017-07-20T16:29:24Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Rafaela Maria Seabra Silva.pdf: 1206163 bytes, checksum: 40c5b3e504a66706b66919d7543260cc (MD5)<br>Made available in DSpace on 2017-07-20T16:29:24Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Rafaela Maria Seabra Silva.pdf: 1206163 bytes, checksum: 40c5b3e504a66706b66919d7543260cc (MD5) Previous issue date: 2010-03-05<br>Leucem

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Mancardi, David. "Rôles pro-inflammatoires des RFcγIV murins, et de leurs deux équivalents fonctionnels humains, les RFcγI et les RFcεI(αγ)". Paris 6, 2009. http://www.theses.fr/2009PA066504.

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Un nouveau RFc, nommé RFcγIV, a été récemment cloné. Ce sont des RFc activateurs murins pour les IgG2 exprimés par les macrophages et les neutrophiles. Ils n’existent pas chez l’homme. Nous avons caractérisé des propriétés biologiques de ces RFc et recherché s’ils avaient des équivalents fonctionnels humains. Nous avons mis en évidence une interaction de faible affinité entre les RFcγIV et les IgE. Cette interaction participe à l’induction d’une inflammation pulmonaire. Dans des modèles d’inflammation dépendante des IgG, les RFcγIV sont capables d’induire une arthrite auto-immune et des chocs

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LAUNAY, PIERRE. "Fonctions et signalisations alternatives du rfc alpha dependantes de l'association avec la chaine gamma (doctorat : immunologie)." Paris 5, 1999. http://www.theses.fr/1999PA05N039.

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Compaleo, Joshua. "Accurate Clutter Power Modeling Technique for Very LowGrazing Angles with RFC Capable Radar Design and Demonstration." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595563370860726.

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Decraene, Maud. "Mise en place de la réponse immunitaire orchestrée par les cellules dendritiques humaines : caractérisation et étude fonctionnelle du rôle des RFcγ". Paris 6, 2005. http://www.theses.fr/2005PA066130.

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Ibrahim, Isak Georgina. "Studies on Translation Initiation and Termination in Escherichia coli." Doctoral thesis, Stockholms universitet, Institutionen för genetik, mikrobiologi och toxikologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-69954.

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Translation initiation factor 1 (IF1) has been shown to be an RNA chaperone. In order to find functional interactions that IF1 may have with rRNA, we have isolated second-site suppressors of a cold-sensitive IF1 mutant. Joining of the ribosomal subunit seems to be affected in the IF1 mutant strain and the suppressive effect is a consequence of decreasing the available pool of mature 50S subunits. The results serve as additional evidence that IF1 is an RNA chaperone and that final maturation of the ribosome takes place during translation initiation. In this study we have also investigated the e

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Grossetête-Pedron, Béatrice. "Role du rfc alpha (cd89) dans la physiopathologie de la maladie de berger et de l'infection a vih." Paris 5, 1999. http://www.theses.fr/1999PA05N115.

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Díaz, Puentes Alfredo Andrés. "Integración de SAP y Aplicaciones Legadas a Través de SOA." Tesis, Universidad de Chile, 2008. http://repositorio.uchile.cl/handle/2250/104945.

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El objetivo general del presente trabajo de título es un caso real de integración entre el ERP de SAP y los legacy del área de logística de una compañía distribuidora de combustible en Chile utilizando los principios que el patrón de diseño SOA ofrece y con la ayuda de herramientas comerciales que implementan y facilitan la integración entre sistemas computacionales heterogéneos. El área de logística de la compañía cuenta con una variedad de aplicaciones legacy Web del tipo J2EE que utilizan de manera independiente y que les permiten realizar la programación de los pedidos de combustible

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Abrisqueta, Costa Pau. "Tratamiento de primera línea con rituximab combinado con fludarabina, ciclofosfamida y mitoxantrone (RFCM) y mantenimiento con rituximab en pacientes con leucemia linfática crónica." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/283529.

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La leucemia linfática crónica (LLC) es la leucemia más frecuente en la edad adulta en los países occidentales, y se caracteriza por la acumulación y proliferación de linfocitos clonales B maduros CD5+ en la sangre, médula ósea, y ganglios linfáticos. La mediana de supervivencia de los pacientes es de alrededor de 10 años aunque su curso clínico es heterogéneo. Durante varias décadas el tratamiento de esta enfermedad se había basado en el empleo de agentes alquilantes como el clorambucilo, en los análogos de la purinas, o en la asociación de ambos, como la combinación de fludarabina y ciclofosf

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Nieke, Franziska. "Beeinflussung der intestinalen Folatresorption durch Umweltkontaminanten am Beispiel eines humanen in vitro Modells." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-154886.

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Folate sind als Überträger von C1-Fragmenten verschiedener Oxidationsstufen direkt an der Nukleinsäuresynthese beteiligt und spielen somit eine entscheidende Rolle im Zellstoffwechsel. So kann ein suboptimaler Folatstatus zur Ausprägung einer klinischen Symptomatik führen, die sich primär in Zellen mit hoher Teilungsrate manifestiert. Dabei gilt die megaloblastäre Anämie als Leitsymptom für einen akuten Folatmangel. Herausragende Bedeutung besitzen Folate in der Schwangerschaft, wo ihnen bei der Entwicklung des fetalen Nervensystems eine besondere Rolle zukommt. Bei einem zu niedrigen Serumfol

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Pujol, F. (François). "Experiments on fatty acids chain elongation and glycan flipping in the ER membrane." Doctoral thesis, University of Oulu, 2009. http://urn.fi/urn:isbn:9789514290695.

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Abstract Very long chain fatty acids (VLCFA) are essential molecules that take part in many different cellular processes such as membrane pore stabilization, membrane trafficking and signaling pathways. The fatty acid elongation pathway in yeast has been studied for about a decade. As part of our work on cellular VLCFA elongation, we identified and characterized the condensing enzyme as well as ketoacyl reductases of the elongation pathway in cotton. In order to identify the yeast 3-hydroxyacyl-CoA dehydratase, we introduced a redundancy in this function by engineering a chimera consisting

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Veronesi, Junior José Ronaldo. "A eficácia da reeducação postural global através do reequilíbrio funcional corporal (RPG/RFC) na correção postural e no reequilíbrio muscular." reponame:Repositório Institucional da UnB, 2006. http://repositorio.unb.br/handle/10482/5219.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, 2006.<br>Submitted by wesley oliveira leite (leite.wesley@yahoo.com.br) on 2009-11-02T17:05:11Z No. of bitstreams: 1 DISSERTACAO FINAL JOSE RONALDO VERONESI JUNIOR.pdf: 1474934 bytes, checksum: 0bb8299fd305b81a21573e89cfa4b04d (MD5)<br>Approved for entry into archive by Gomes Neide(nagomes2005@gmail.com) on 2010-07-12T19:42:18Z (GMT) No. of bitstreams: 1 DISSERTACAO FINAL JOSE RONALDO VERONESI JUNIOR.pdf: 1474934 bytes, checksum: 0bb8299fd305b81a21573e89cfa4b04d (MD5)<br>Made available in DSpace on 2010-07-12T

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Amigorena, Sebastian. "Activation, proliferation et differenciation des lymphocytes b murins : flux ioniques, expression des rfc gamma de type deux et regulation isotypique." Paris 7, 1990. http://www.theses.fr/1990PA077004.

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Le travail presente dans cette these concerne l'etude de certains aspects du developpement des lymphocytes b quiescents en plasmocytes. D'une part, nous avons etudie l'expression des recepteurs de type deux pour la portion fc des igg (rfc gamma deux), ainsi que l'expression et le role de canaux k#+ lors de l'activation et de la proliferation de lymphocytes b murins. Nous avons montre que: 1) la forme beta 1 des rfc gamma deux est exprimee majoritairement dans les lymphocytes b quiescents et actives; 2) l'expression membranaire des rfc gamma deux augmente lorsque les lymphocytes b entrent en ph

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Martel, Velasquez Victor Ronald. "Diseño de una red de comunicación VPN sobre internet para un Distribuidor Autorizado de Claro basado en el RFC 2764." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/625693.

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El presente proyecto sobre redes de comunicación VPN sobre internet nos muestra una guía de configuraciones necesarias por requisitos en base al RFC 2764 incluyendo las funcionalidades de la red que permitirá ejecutar las acciones requeridas para agilizar los procesos de negocio mediante un eficiente uso de los recursos TI para la disponibilidad de la información. Actualmente las empresas desean tener presencia en nuevos mercados, por lo que se expanden a nuevas sucursales en distintos distritos y hasta en el interior del país lo que origina la necesidad de mantenerse conectados en todo momen

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Ťápal, Tomáš. "Zefektivnění analýzy počítačové sítě 10Gbit/s." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220194.

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The master’s thesis consists of several parts. Describes the technology 10 Gbps Ethernet. Analyzer Ixia and Endace presents, especially their use for traffic analysis and stress testing the network devices. It deals with documents RFC concerning the routers and switch testing. Thesis includes the reports of tests switches and router performed by RFC 2544 and RFC 2889 documents. Part of the thesis is dedicated to COMBO FPGA cards. Documentations to the analyzers is created in this thesis and macro is on the CD for presentation of measurement results.

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Pilčík, Jan. "Metody měření přenosových rychlostí na Internetu." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217279.

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Due to a signifikant development of computer networks in the last few years the demands for measurement of network metrics increased. This master´s thesis is dealing with standards for testing and test techniques used for the measurement of network metrics. Further it compares the existing free accessible measurement tools and metrics measures them. Finaly the thesis draws up a web application for measurement of the basic network metrics.

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Martin-Verdeaux, Sophie. "Mécanismes moléculaires de l'exocytose mastocytaire médiée par le RFc[epsilon]I : rôle du complexe SNARE et des protéines régulatrices MUNC18 et RAB3D." Paris 5, 2002. http://www.theses.fr/2002PA05P609.

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Les mastocytes sont des cellules du système immunitaire hautement spécialisées, impliquées dans des réactions inflammatoires et allergiques. Suite à l'agrégation des récepteurs de haute affinité pour les IgE(RFc[epsilon]I)présents à la surface membranaire, les mastocytes sécrètent massivement et rapidement leur contenu granulaire. Cette dégranulation, mettant en jeu des mécanismes Ca2+- et PKC-dépendants, mobilise presque tous les granules intracellulaires par un mécanisme d'exocytose cumulative, impliquant, d'une part la fusion hétérotypique des granules avec la membrane plasmique et d'autre

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Knoll, Thomas Martin. "BGP Extended Community Attribute for QoS Marking." Universitätsbibliothek Chemnitz, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-200800767.

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This document specifies a simple signalling mechanism for inter-domain QoS marking using a BGP Extended Community QoS Attribute. Class based packet forwarding for delay and loss critical services is currently performed in an individual AS internal manner. The new QoS marking attribute makes the QoS class setup within the IP prefix advertising AS known to all access and transit ASes. This enables individual (re-)marking and forwarding treatment adaptation to the original QoS class setup of the respective IP prefix. The attribute provides the means to signal QoS markings on different layers,

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Brunati, Silvana. "Régulation de la production des IgG par les lymphocytes T RF#c gamma positifs." Paris 6, 1990. http://www.theses.fr/1990PA066058.

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Dans ce travail, nous avons analysé l'action suppressive des cellules d'un hybridome T exprimant des récepteurs FC gamma, producteur d'IgG-BF, (T2D4. C1) sur la production d'IgG par des cellules d'hybridomes B. Le système expérimental consiste en la co-culture de différents clones d'hybridomes B (producteurs soit d'IgG (H et L) (UN2. C3), soit uniquement de chaines L (UN2. C17. K1) avec T2D4. C1 ou avec D10C5 (ce dernier est un hybridome T n'exprimant pas de récepteurs FC gamma et ne produisant pas d'IgG-BF). Nous avons montré que seul T2D4. C1 inhibe la sécrétion des IgG par les cellules UN2.

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Metz, Josué Claudio. "Avaliação do uso combinado de pó de aciaria elétrica (PAE) com resíduo do forno de cal (RFC) na hidratação de pastas de cimento." Universidade do Vale do Rio dos Sinos, 2016. http://www.repositorio.jesuita.org.br/handle/UNISINOS/5991.

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Submitted by Silvana Teresinha Dornelles Studzinski (sstudzinski) on 2016-12-22T12:03:13Z No. of bitstreams: 1 Josué Claudio Metz_.pdf: 3580473 bytes, checksum: 4bb7f81d4d0a95ef4e39a7d4dffb0599 (MD5)<br>Made available in DSpace on 2016-12-22T12:03:13Z (GMT). No. of bitstreams: 1 Josué Claudio Metz_.pdf: 3580473 bytes, checksum: 4bb7f81d4d0a95ef4e39a7d4dffb0599 (MD5) Previous issue date: 2016-09-19<br>Nenhuma<br>A concepção de desenvolvimento sustentável tem resultado no aumento de pressões ambientais para a melhoria da eficiência na utilização de recursos, e para a redução das emissões e

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Dutertre, Charles-Antoine. "De l'importance de la caractérisation des différentes isoformes de RFC gamma des cellules NK pour l'optimisation fonctionnelle des anticorps monoclonaux à usage thérapeutique." Paris 7, 2008. http://www.theses.fr/2008PA077132.

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De gros efforts ont été faits pour optimiser les propriétés cytotoxiques des anticorps monoclonaux (AcM) à usage thérapeutique, en particulier leur capacité d'engagement du RFcγIIIA (CD16) activateur exprimé à la surface des cellules NK capables d'induire une cytotoxicité cellulaire dépendante d'anticorps (ADCC). La première partie de nos travaux a visé à déterminer l'expression de RFcγll par les cellules NK, ainsi que leur rôle dans le contrôle de l'ADCC, et nous a permis de mettre en évidence une nouvelle sous-population de cellules NK CD56dim/CD3ˉ/NKp46⁺/RFcγlllAbright/RFcγllbright expriman

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Malbec, Odile. "La trans-inhibition : une nouvelle propriété inhibitrice des RFcγIIB". Phd thesis, Université Pierre et Marie Curie - Paris VI, 2012. http://tel.archives-ouvertes.fr/tel-00833016.

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L'engagement des récepteurs de forte affinité pour les IgE (RFcγI), qui contiennent des motifs d'activation nommés ITAM, induit l'activation des mastocytes et des basophiles. Les récepteurs de faible affinité pour les IgG (RFcγIIB) contiennent des motifs d'inhibition nommés ITIM et inhibent l'activation cellulaire lorsqu'ils sont coagrégés aux récepteurs à ITAM. Les RFcγIIB inhibent également la prolifération cellulaire induite par les récepteurs à activité tyrosine kinase comme Kit. Les propriétés inhibitrices des RFcγIIB reposent sur le recrutement de l'inositol phosphatase SHIP1, qui dégrad

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Fornůsek, Jan. "Návrh softwarového prostředí pro zpracování dat z měření telekomunikačních sítí." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219465.

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This document introduces the reader with measurements related to optical networks. This is not a list of all measurements. There are only mentioned selected measurements related to input files into the developed application. The practical part describes the application's documentation.

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Horváth, Tomáš. "Simulace a měření služeb Triple Play v sítích FTTx." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220307.

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The aim of this thesis was to ascertain with the measurement methods of passive optical networks and the creation of a simulation model that corresponds to the measured network and comparison of results. The first chapter deals with Triple Play services, which are focused on different services (transmission of television signals, voice and data transmission). Each service consists of a subchapter and presents a detailed description of the parameters associated with the transmission. The second chapter of the theoretical part consists of an analysis of passive optical networks according to term

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Nwup, Emineimo Kennedy, and Adesola Idris Akande. "Evaluation of the pre IEEE 802.11s RFC : Aspects of the Design and Implementation of the Mesh Station with RA-OLSR in the C-Core." Thesis, Blekinge Tekniska Högskola, Avdelningen för telekommunikationssystem, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3883.

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The demand for ubiquitous networks has pushed the designs of networks all the way. The requirement for access point to be integrated into IEEE 802.3 standard and other networks has always been a sore point in the limitation of wireless coverage of IEEE 802.11 standard networks. Wireless Mesh Network (WMN) is expected to be the future of the next generation wireless network. It is experiencing a fast growing development due to its attractive features which includes high reliable connectivity, easy deployment, self healing, self configuring, flexible network expansion etc. Hence the mobility of

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