Academic literature on the topic 'Rhabdomyosarcoma'

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Journal articles on the topic "Rhabdomyosarcoma"

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Manzoor, Mohammad, Bismah Ahmad, Adnan Sarwar, et al. "Epidemiological And Histopathologic Study Of Rhabdomyosarcoma cases in a tertiary Care hospital of Peshawar." Pakistan BioMedical Journal 4, no. 2 (2021): 292–96. http://dx.doi.org/10.54393/pbmj.v4i2.253.

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 Aim: This study aimed to find out rhabdomyosarcoma’s (RMS) histopathological and immunohistochemical features. Settings: The current study was carried out at the Department of Pathology, Section of Histopathology, Khyber Teaching Hospital Peshawar. The study duration was between from 1st January 2015 to 30th of December 2020. Results: In the current study, all the 300 occurrences were found to be relevant. The most prevalent rhabdomyosarcoma was embryonal rhabdomyosarcoma (ERMS) (87.4%), followed by alveolar rhabdomyosarcoma (ARMS) (9.4%). In the current study we found that embryonal rh
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Rekhi, Bharat, Pawan Upadhyay, Manoj P. Ramteke, and Amit Dutt. "MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabdomyosarcomas with aggressive clinical outcomes." Modern Pathology 29, no. 12 (2016): 1532–40. http://dx.doi.org/10.1038/modpathol.2016.144.

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Abstract Recurrent mutations in the myogenic transcription factor MYOD1 and PIK3CA were initially described in a subset of embryonal rhabdomyosarcomas. Recently, two independent studies demonstrated presence of MYODI (L122R) mutations as the basis to re-classify a spindle cell rhabdomyosarcoma, along with a sclerosing rhabdomyosarcoma, distinct from an embryonal rhabdomyosarcoma. We analyzed a much larger cohort of 49 primary rhabdomyosarcoma tumor samples of various subtypes, collected over a period of 9 years, for the presence of MYOD1 (L122R), PIK3CA (H1047), and PIK3CA (E542/E545) mutation
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Şahan, Mehmet Hamdi, Şeyma Eseoğlu, and Melih Akşamoğlu. "A rare case of primary pulmonary embryonal rhabdomyosarcoma in children." Surgery on Children 2, no. 1 (2025): 33–35. https://doi.org/10.51271/soc-0031.

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Rhabdomyosarcoma is one of the most common soft tissue sarcomas in adolescence and young adults. Histologically, rhabdomyosarcoma has many subgroups, including embryonal, alveolar, pleomorphic, and spindle cell/sclerosing rhabdomyosarcomas. More than 50% of embryonal rhabdomyosarcomas occur in the head and neck region. The retroperitoneum and pelvis are less common sites of involvement. Primary pulmonary embryonal rhabdomyosarcoma is extremely rare. A 3-year-old girl presented with symptoms of cough and shortness of breath. A mass lesion with regular contours, approximately 3x3 cm in size, con
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Roldan, Rodante A., Erasmo Gonzalo DV Llanes, and Romeo L. Villarta. "Embryonal Rhabdomyosarcoma of the Mandible." Philippine Journal of Otolaryngology-Head and Neck Surgery 21, no. 1-2 (2005): 36–38. http://dx.doi.org/10.32412/pjohns.v21i1-2.831.

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Objectives: 1] To describe a case of an embryonal rhabdomyosarcoma presenting as a radiolucent mandibular mass in a 3-year-old child. 2] To review existing literature on the clinical picture and pathophysiology of intraosseous rhabdomyosarcoma. 3] To identify learning points in the diagnosis of intraosseous rhabdomyosarcoma.
 
 Design: Case report.
 
 Setting: A tertiary referral hospital.
 
 Patients: One (1)
 
 Results: A case of a 3-year-old child with a radiolucent mandibular mass is described. The final histopathologic report turned out to be embryo
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Abraham, Jinu, Laura D. Nelon, Courtney B. Kubicek, et al. "Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model." Sarcoma 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/130484.

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Rhabdomyosarcoma is an aggressive childhood malignancy, accounting for more than 50% of all soft-tissue sarcomas in children. Even with extensive therapy, the survival rate among alveolar rhabdomyosarcoma patients with advanced disease is only 20%. The receptor tyrosine kinase Epidermal Growth Factor Receptor (EGFR) has been found to be expressed and activated in human rhabdomyosarcomas. In this study we have used a genetically engineered mouse model for alveolar rhabdomyosarcoma (ARMS) which faithfully recapitulates the human disease by activating the pathognomic Pax3:Fkhr fusion gene and ina
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Mccluggage, W. G., T. F. Lioe, H. R. Mcclelland, and H. Lamki. "Rhabdomyosarcoma of the uterus: Report of two cases, including one of the spindle cell variant." International Journal of Gynecologic Cancer 12, no. 1 (2002): 128–32. http://dx.doi.org/10.1136/ijgc-00009577-200201000-00021.

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Abstract.McCluggage WG, Lioe TF, McClelland HR, Lamki H. Rhabdomyosarcoma of the uterus: Report of two cases, including one of the spindle cell variant.Most uterine sarcomas fall into the category of leiomyosarcoma, endometrial stromal sarcoma, or undifferentiated sarcoma. Pure rhabdomyosarcomas are extremely rare, although a rhabdomyosarcomatous element may be present as a component of an adenosarcoma or carcinosarcoma (malignant mixed müllerian tumor). This report describes two uterine rhabdomyosarcomas in 28- and 67-year-old women. These were of spindle cell and pleomorphic types, respectiv
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Sinha, Kavita, Home Nath Adhikari, and Pooja Baidya. "Uterine Cervix Rhabdomyosarcoma : A Case Report." Journal of Nepalgunj Medical College 21, no. 2 (2023): 46–48. http://dx.doi.org/10.3126/jngmc.v21i2.62809.

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Rhabdomyosarcoma is a malignant tumor that arises from embryonal skeletal muscle cells. It is responsible for 3% of cancer cases among children aged from 0 to 14 and 1% among adolescent and young adult aged from 15 to 19. Embryonal Rhabdomyosarcoma is the most prevalent subtype in the female genital tract and Botryoid sarcomas being a polypoid variant. In young patients, the majority of genital tract rhabdomyosarcomas occur in vagina; however, the most common site being cervix followed by uterine corpus, in adults. We hereby report a case of 24 years lady P2L2 diagnosed as Botryoid Embryonal R
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Al-Mubarak, Luluah, and Sultan Al-Khenaizan. "A Wolf in Sheep's Disguise: Rhabdomyosarcoma Misdiagnosed as Infantile Hemangioma." Journal of Cutaneous Medicine and Surgery 13, no. 5 (2009): 276–79. http://dx.doi.org/10.2310/7750.2009.08048.

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Background: Rhabdomyosarcomas are a heterogeneous group of malignant tumors representing the most common soft tissue sarcoma of childhood. A delay in diagnosis is not uncommon. Objective: To report a boy with paranasal rhabdomyosarcoma who was misdiagnosed and treated for infantile hemangioma. Methods and Results: A 2-year-old Saudi boy who presented with a progressively increasing nasal mass for 18 months was misdiagnosed and treated for infantile hemangioma at an outside hospital. Histopathologic examination revealed paranasal rhabdomyosarcoma. Conclusion: We review some clinical clues that
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Marzouk, Sawssen Ben, Wael Ferjaoui, Adel Jelassi, Nizar Cherni, Mohamed Hedi Mannai, and Mohamed Bechir Khalifa. "Rhabdomyosarcoma of the Buttock, Rare Location." Clinical Case Reports and Studies 3, no. 3 (2023): 1–2. http://dx.doi.org/10.59657/2837-2565.brs.23.070.

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Rhabdomyosarcoma is a common mesenchymal tumor in children. it is a rare tumor in adults and exceptional in the elderly. The most frequent locations of rhabdomyosarcomas are the head, neck, orbit and urinary tract, these locations are considered favorable. Other locations are considered unfavorable. We report the case of cutaneous rhabdomyosarcoma of the buttock in a 61-year-old man operated on at our service.
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Vadgama, Bhumita, Neil James Sebire, Marian Malone, and Alan Drummond Ramsay. "Sclerosing Rhabdomyosarcoma in Childhood: Case Report and Review of the Literature." Pediatric and Developmental Pathology 7, no. 4 (2004): 391–96. http://dx.doi.org/10.1007/s10024-003-9453-5.

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Rhabdomyosarcoma is the most common soft tissue malignancy in children but is rare in adults. The latest World Health Organization classification of soft tissue tumors recognizes embryonal, alveolar, and pleomorphic rhabdomyosarcomas. More recently, a sclerosing variant of rhabdomyosarcoma has been recognized and reported in seven adult patients. We describe a pediatric case of sclerosing rhabdomyosarcoma presenting as a sacral mass in a 3-year-old girl. Morphologically, the tumor showed a prominent sclerosing hyaline matrix and demonstrated pseudovascular and microalveolar architectural foci.
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Dissertations / Theses on the topic "Rhabdomyosarcoma"

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Anderson, William John. "Molecular characterisation of rhabdomyosarcoma." Thesis, Institute of Cancer Research (University Of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312950.

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Scrable, Heidi. "Molecular genetics of childhood rhabdomyosarcoma." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=74265.

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Rhabdomyosarcoma is a class of malignant neoplasms composed of cells histologically resembling fetal striated muscle. It is the most common soft tissue tumor of children, adolescents, and young adults. In this Thesis, I demonstrate that the rhabdomyosarcoma tumor class is delimited in molecular genetic terms by the expression of the MyoD gene, and that loss of alleles on chromosome 11 distinguishes between the embryonal and alveolar subtypes. The elucidation of this genotypic distinction resolved the paradox between phenotypic variation and an apparent histogenetic relatedness between and amon
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Poli, Elena. "DNA METHYLATION ANALYSIS IN RHABDOMYOSARCOMA." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3424380.

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Rhabdomyosarcoma (RMS) is a highly aggressive pediatric soft-tissue sarcoma. It is mainly classified into two major subtypes characterized by alveolar (ARMS) and embryonal (ERMS) histologies. ARMS are characterized by a more aggressive behavior with a higher tendency to present metastasis at diagnosis and to relapse after treatment. Approximately 80% of ARMS harbour the reciprocal chromosomal translocation t(2;13)(q35;q14) and, less commonly, the variant translocation t(1;13)(p36;q14), in which PAX3 and FOXO1, or PAX7 and FOXO1 genes, respectively, are juxtaposed. Unfortunately, no such specif
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Chalk, Jeremy. "A molecular genetic investigation of rhabdomyosarcoma." Thesis, Open University, 1997. http://oro.open.ac.uk/57658/.

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Alveolar rhabdomyosarcoma is characterised by a t(2;13)(q35;qI4) chromosome translocation, which leads to the fusion of the P AX3 artd the FKHR genes. The resulting fusion gene encodes a chimeric protein which has aberrant transcriptional activity. The data here describes the molecular definition of the genomic breakpoints on both derivative chromosomes in one case and the derivative chromosome 13 breakpoints in two other cases. The DNA sequences adjacent to the breakpoints on the derivative chromosome 13 are remarkable for their resemblartce to recognition sequences for the protein trartslin.
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Roberts, Ian. "Molecular cytogenetic analysis of paediatric rhabdomyosarcoma." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621125.

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Mohamed, Abdalla Ahmed Diaai. "The Hippo effector TAZ in rhabdomyosarcoma." Thesis, University of Aberdeen, 2015. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=228577.

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Persistent hyperactivity of the Hippo effector YAP in activated but not quiescent satellite cells (muscle stem cells) can give rise to embryonal rhabdomyosarcoma (ERMS). Taz is a paralogue of Yap and both have similar functions in most cell types. However, one report has suggested that Taz can, unlike Yap, promote the differentiation of myoblasts into myotubes. To further characterise the role of Taz in the muscle lineage and rhabdomyosarcoma TAZ abundance and localisation in rhabdomyosarcoma tissue arrays were assessed to test for association with clinical outcome. Additionally, wildtype TAZ
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Gavino, Belinda Joy E. "Nickel induced rhabdomyosarcoma in cultured cardiac myocytes." Tallahassee, Fla. : Florida State University, 2008. http://purl.fcla.edu/fsu/lib/digcoll/undergraduate/honors-theses/341766.

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Thesis (Honors paper)--Florida State University, 2008.<br>Advisor: Dr. P. Bryant Chase, Florida State University, College of Arts and Sciences, Dept. of Biological Science. Includes bibliographical references.
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Sun, Danqiong. "Molecular mechanisms in myogenesis and in rhabdomyosarcoma." Diss., Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/2751.

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Feldmann, Jamie. "Analysis of myogenin function in rhabdomyosarcoma cells /." Available to subscribers only, 2009. http://proquest.umi.com/pqdweb?did=1885443171&sid=5&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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Thesis (M.S.)--Southern Illinois University Carbondale, 2009.<br>"Department of Molecular Biology, Microbiology and Biochemistry." Includes bibliographical references (p. 46-48). Also available online.
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Annavarapu, Srinivas Rao. "Characterisation of Wnt signalling pathway in rhabdomyosarcoma." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3009225/.

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Introduction: Rhabdomyosarcoma (RMS) remains one of the most challenging tumours in paediatric oncology, accounting for around 5% of all malignant paediatric tumours. Of the two major subtypes of RMS, embryonal and alveolar, the latter portends a poorer clinical outcome. Canonical Wnt signalling pathway is an important evolutionarily conserved signalling pathway that is required for muscle development and embryonal somite patterning. β-Catenin is a potent nuclear transcriptional activator and is the central effector of the canonical Wnt signalling pathway. Interestingly, constitutional activat
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Books on the topic "Rhabdomyosarcoma"

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Parker, James N., and Philip M. Parker. The official parent's sourcebook on childhood rhabdomyosarcoma. Icon Health Publications, 2002.

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M, Maurer Harold, Ruymann Frederick B, and Pochedly Carl, eds. Rhabdomyosarcoma and related tumors in children and adolescents. CRC Press, 1991.

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Agnes, Chan Sze Wah. Identification of differentially expressed genes in rhabdomyosarcoma. 2002.

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Gee, Matthew Frederick William. Studies of autocrine VEGF signalling in rhabdomyosarcoma. 2004.

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Semel, Robert L. The Third Strike: A Father's Story of His Son's Struggle With Cancer. Booklocker.com, 2003.

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Pandita, Ajay. Molecular cytogenetic analysis and gene amplification in rhabdomyosarcoma and neuroblastoma. 2000.

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Bhumbra, Rej S., Panagiotis D. Gikas, Sammy Hanna, Jakub Jagiello, and Stephen R. Cannon. Malignant tumours of soft tissues. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.002004.

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♦ Malignant vascular tumours of soft tissue♦ Synovial sarcoma♦ Malignant peripheral nerve sheath tumours♦ Rhabdomyosarcoma♦ Leiomyosarcoma♦ Epithelioid sarcoma♦ Clear cell sarcoma♦ Malignant fibrous histiocytoma♦ Chordoma.
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Taylor, Roger E. Principles of paediatric radiation oncology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199696567.003.0020.

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Chapter 15 discusses the principles of paediatric radiation oncology, and addresses quality assurance, chemotherapy/radiotherapy interactions, Leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, Neuroblastoma, Rhabdomyosarcoma, Ewing’s sarcoma/peripheral primitive neuroectodermal tumour, Osteosarcoma, central nervous system tumours, Intensity-modulated radiotherapy, and proton therapy for paediatric tumours.
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Publications, ICON Health. The Official Parent's Sourcebook on Childhood Rhabdomyosarcoma: A Revised and Updated Directory for the Internet Age. ICON Health Publications, 2002.

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Wang, Weiguang. The study of the oncogenic of PAX3, PAX3-FKHR and IGF-11 genes in rhabdomyosarcoma and medulloblastoma. 1998.

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Book chapters on the topic "Rhabdomyosarcoma"

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De Schepper, A. M. A., and H. R. M. Degryse. "Rhabdomyosarcoma." In Magnetic Resonance Imaging of Bone and Soft Tissue Tumors and Their Mimics. Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0997-7_19.

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Campanacci, Mario. "Rhabdomyosarcoma." In Bone and Soft Tissue Tumors. Springer Vienna, 1999. http://dx.doi.org/10.1007/978-3-7091-3846-5_73.

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Mocellin, Simone. "Rhabdomyosarcoma." In Soft Tissue Tumors. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58710-9_224.

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Loh, Amos, and Bhaskar Rao. "Rhabdomyosarcoma." In Pediatric Surgery. Springer Berlin Heidelberg, 2020. http://dx.doi.org/10.1007/978-3-642-38482-0_149-1.

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Moore, S., and P. J. Greyling. "Rhabdomyosarcoma." In ABC of Pediatric Surgical Imaging. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-89385-1_64.

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Glicenstein, Julien, Jacques Ohana, and Caroline Leclercq. "Rhabdomyosarcoma." In Tumours of the Hand. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-71834-2_28.

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Alvarez-Allende, Carlos R., and Roshni Dasgupta. "Rhabdomyosarcoma." In Fundamentals of Pediatric Surgery. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-27443-0_99.

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Yue, Ning J., Kent Lambert, Jay E. Reiff, et al. "Rhabdomyosarcoma." In Encyclopedia of Radiation Oncology. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-540-85516-3_94.

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Mostafa, Badr Eldin. "Rhabdomyosarcoma." In Encyclopedia of Otolaryngology, Head and Neck Surgery. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-23499-6_721.

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Franchi, Alessandro. "Rhabdomyosarcoma." In Encyclopedia of Pathology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-28845-1_4931-1.

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Conference papers on the topic "Rhabdomyosarcoma"

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Moukarzel, L., T. Heaton, and N. Abu-Rustum. "112 Pediatric abdominal trachelectomy for rhabdomyosarcoma." In IGCS Annual 2019 Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-igcs.112.

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Xu, Mark C., Muhammad Ghani, Annie Apple, et al. "FXR1 Expression Profiles In Pediatric Rhabdomyosarcoma." In AAP National Conference & Exhibition Meeting Abstracts. American Academy of Pediatrics, 2021. http://dx.doi.org/10.1542/peds.147.3_meetingabstract.937.

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Akdemir, Celal, Özgür Erdogan, Muzaffer Sanci, Halil Ibrahim Yildiz, Esra Canan Kelten Talu, and Duygu Ayaz. "#553 Embryonal rhabdomyosarcoma of the cervix." In ESGO 2023 Congress. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/ijgc-2023-esgo.159.

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Cheuk, Adam Tai Chi, and Javed Khan. "Abstract A241: Targeting FGFR4 for rhabdomyosarcoma therapy." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Nov 12-16, 2011; San Francisco, CA. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1535-7163.targ-11-a241.

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Koneru, Sahitya, Silky Jain, Shalini Mishra, Sandeep Jain, and Gauri Kapoor. "Pediatric vaginal rhabdomyosarcoma: Report of 2 cases." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685381.

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Introduction: Rhabdomyosarcoma (RMS) arising in the female genital tract is rare accounting for 3.5% of all RMS cases. Approximately half these occur in the vagina, a site that has been associated with a favorable prognosis. Optimal loco-regional treatment for patients with vaginal RMS remains controversial since wide local excision is mutilating and often not done. Two cases of vaginal RMS are reported who underwent chemotherapy and local control with brachytherapy. Methods: Retrospective chart review was done between 2011 and 2015. During this interval, out of 31 cases of pediatric RMS manag
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Sobral, Lays M., and Paul Jedlicka. "Abstract A33: Histone demethylase KDM3A in rhabdomyosarcoma." In Abstracts: Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1557-3265.sarcomas17-a33.

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Setic-Avdagic, I., M. Becirovic, and M. Tuhcic. "Alveolar Rhabdomyosarcoma in Nasal Cavity – Case Report." In Abstract- und Posterband – 89. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Forschung heute – Zukunft morgen. Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1640163.

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Reindl, L. M., L. Jalili, F. Rothweiler, et al. "NK cell immunotherapy against chemotherapy-resistant rhabdomyosarcoma." In 34. Jahrestagung der Kind-Philipp-Stiftung für pädiatrisch onkologische Forschung. Georg Thieme Verlag, 2023. http://dx.doi.org/10.1055/s-0043-1768537.

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Yeo, Chong Xian Felix, Ying Ying Woh Kham, Chu Sing Daniel Lim, Kian Hwa Tan, and Eng Lee Tan. "Optimization of electrofusion in vitro for rhabdomyosarcoma cells." In 2011 Defense Science Research Conference And Expo (DSR). IEEE, 2011. http://dx.doi.org/10.1109/dsr.2011.6026864.

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Issaq, Sameer, Beverly Teicher, and Anne Monks. "Abstract C152: Characterizing rhabdomyosarcoma and osteosarcoma cellular metabolism." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Oct 19-23, 2013; Boston, MA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1535-7163.targ-13-c152.

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Reports on the topic "Rhabdomyosarcoma"

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Smeulders, Naima, and Olga Slater. Genitourinary rhabdomyosarcoma. BJUI Knowledge, 2019. http://dx.doi.org/10.18591/bjuik.0293.

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Jordan, Jacob. On-treatment changes in pediatric parameningeal rhabdomyosarcoma treated with upfront proton therapy. University of Tennessee Health Science Center, 2022. http://dx.doi.org/10.21007/com.lsp.2022.0008.

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The project is focused on the effects of longitudinal changes in patient and tumor anatomy on the delivered treatment plan during proton radiotherapy for the treatment of pediatric Para meningeal rhabdomyosarcoma. The study will investigate the effects of change on dose delivered to organs-at-risk near the tumor. This effort will extend the analysis of changes to the organs-at-risk to all the cases in the study and add an additional case meeting the study criteria.
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Noonan, Lauren, Aisling Barry, Theresa O'Donovan, Annemarie Devine, Andrew England, and Mark McEntee. Proton beam therapy versus current standard radiation therapy in the treatment of rhabdomyosarcoma in children: A systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0081.

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