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Dissertations / Theses on the topic 'Rheumatoid arthritis Immunological aspects'

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Published: 4 June 2021

Last updated: 31 January 2023

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1

Sverdrup, Berit. "Aspects of the role of mineral oil as immunological adjuvant in rheumatoid arthritis /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-112-8/.

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2

Effertz, Bernard Stephen. "The humoral immune response to streptococcal cell wall-induced arthritis in the rat." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184877.

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I investigated the humoral immune response to streptococcal cell walls (SCW) in arthritis susceptible Lewis and resistant Fisher rats. All rats were given a single intraperitoneal injection of either SCW or saline (controls). Rats were sacrificed, three rats per time point, over an eleven week period and serum was collected for ELISA. SCW injected Lewis rats produced anti-SCW antibody, whereas control rats did not. Anti-SCW antibody was significantly elevated over controls between days 14-28 (post injection). Both saline and SCW injected Fisher rats produced anti-SCW antibody, but with differe

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3

Nordström, Dan C. E. "Cellular inflammation in arthritis a study of clinical, histological, and immunological aspects in rheumatoid and reactive arthritis /." Hki : Societas scientiarum Fennica, 1989. http://catalog.hathitrust.org/api/volumes/oclc/58508848.html.

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4

Lacey, Derek. "NFκB independent pathway activation of rheumatoid arthritis FLS by macrophage migration inhibitory factor (MIF)". Monash University, Faculty of Medicine, 2003. http://arrow.monash.edu.au/hdl/1959.1/9457.

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5

Penglis, Peter Savas. "The relationships between eicosanoid production and pro-inflammatory cytokines." Title page, contents and summary only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09php3985.pdf.

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Includes bibliographical references (leaves 182-240). Explores alternate strategies that may alter inflammatory cytokine production, particularly tumour necrosis factor đ [tumor necrosis factor-alpha], and therefore provide a possible treatment for rheumatoid arthritis.

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6

Duke, O. L. "Immunological observations in rheumatoid arthritis." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598674.

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7

Bedwell, A. E. "Immunological abnormalities of rheumatoid arthritis." Thesis, University of Bristol, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372005.

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8

Pritchard, M. L. "Psychological aspects of rheumatoid arthritis." Thesis, University of Exeter, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381050.

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9

Milicic, Anita. "Studies of the genetic and immunological basis of rheumatoid arthritis." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275411.

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10

Brink, Mikael. "Presence of immunological markers preceding the onset of rheumatoid arthritis." Doctoral thesis, Umeå universitet, Reumatologi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-102589.

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Rheumatoid arthritis (RA) is a chronic inflammatory disease with an unknown aetiology characterized by joint destruction. Both genetic and environmental factors contribute to the disease development with HLA-DRB1* alleles and smoking identified as most important. The disease is characterized by the presence of autoantibodies, originally by rheumatoid factor (RF) and more recently by anti citrullinated protein/peptide antibodies (ACPA) and antibodies against carbamylated peptides (CarP). These autoantibodies are present, not only after the onset of disease, but also prior to the onset of sympto

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11

Salih, Abdelrazig Mustafa. "A clinical and immunological study of peripheral neuropathy in rheumatoid arthritis." Thesis, Keele University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318158.

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12

Meltzer, Janet R. "Psychological adjustment in juvenile rheumatoid arthritis /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu148758564557603.

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13

Bishop, Carole Marie. "Coping with pain in rheumatoid arthritis." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29207.

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This research investigated the role of coping strategies in reducing the pain experience of rheumatoid arthritis (RA) patients over a seven-day period. Sixty-three patients completed a twice-daily structured dairy consisting of an eight scale revision of the Ways of Coping (WOC), the depression subscale of the Affects Balance Scale (ABS), and a pain visual analogue scale (VAS). Multivariate analyses for repeated measures identified two coping strategies, Self-Care and Positive Reappraisal, as significantly effective in pain reduction. Self-Care includes behavioral attempts to manage the sympto

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14

Ljung, Lotta. "Aspects on inflammation and cardiovascular comorbidity in rheumatoid arthritis." Doctoral thesis, Umeå universitet, Reumatologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57702.

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There is an increased risk for cardiovascular (CV) comorbidity among patients with rheumatoid arthritis (RA), with premature atherosclerosis, and a higher incidence of CV events, compared with the general population. Disease related factors add to the CV risk, and interact with the traditional CV risk factors. The underlying mechanism for this is not completely understood. In active RA there is a loss of muscle mass and an increase in body fat content. Production of cytokines, i.e., adipokines, in the adipose tissue could link the inflammation with the CV system. Control of the inflammation ha

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15

Innala, Lena. "Early rheumatoid arthritis aspects of severity and co-morbidity." Doctoral thesis, Umeå universitet, Reumatologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88477.

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Background Rheumatoid arthritis (RA) is a systemic progressive destructive joint disease with an increased risk for co-morbidity and premature death if untreated. Cardiovascular disease (CVD) is the main cause of death but also other co-morbid conditions contribute to the patient’s shorter life expectancy. Inflammation is important for the development of CVD, but knowledge of its relationship with other co-morbidities is sparse. Early disease modifying anti rheumatic drugs (DMARDs) can suppress disease activity and improve the long-term outcome. The aim of this thesis was to evaluate prospecti

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16

Nissinen, Riikka. "Immunological features of chronic active rheumatoid arthritis : chemokine receptor and cytokine profile in synovial fluid, peripheral blood and gut in patients with rheumatoid arthritis." Helsinki : University of Helsinki, 2003. http://ethesis.helsinki.fi/julkaisut/laa/kansa/vk/nissinen/.

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17

Chu, Sok-iam Peony. "The role of self-efficacy in rheumatoid arthritis patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1994. http://hub.hku.hk/bib/B29689156.

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18

Södergren, Anna. "Epidemiological and pathogenic aspects on cardiovascular disease in rheumatoid arthritis." Doctoral thesis, Umeå universitet, Reumatologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1906.

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Rheumatoid arthritis (RA) is a chronic disabling disease that is associated with a shortened life span. Cardiovascular disease (CVD) contributes to this increased mortality, and also to a great extent to the co-morbidity observed in patients with RA. This thesis aimed to investigate these issues further. The incidence of, and prognosis after an acute myocardial infarction (AMI) /or stroke in a cohort of RA patients was compared with that in the general population within the northern Sweden MONICA register. The standard incidence ratio (SIR) for AMI was 2.9 and for stroke 2.7 in RA patients com

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19

Reckner, Olsson Åsa. "Occupational and environmental aspects on the aetiology of rheumatoid arthritis /." Linköping : Univ, 2003. http://www.bibl.liu.se/liupubl/disp/disp2003/med807s.pdf.

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20

Humby, Frances Claire. "The clinical and immunological significance of ectopic lymphoneogenesis in the rheumatoid synovial membrane." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/28086.

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Despite the development of new biomarkers predicting prognosis in rheumatoid arthritis (RA) remains challenging and targeting of powerful biologics difficult. The presence of ectopic germinal centres (GC) within synovium has long been recognised (ectopic lymphoneogenesis [ELN]) and data have suggested that they manufacture antibody (Ab). High affinity class switched Ab production occurs through class switch recombination (CSR) and somatic hypermutation (SHM) both critically dependent on activation induced cytidine deaminase (AID). However, whether ectopic GCs express AID has not been known. No

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21

Gröndal, Lollo. "The rheumatoid forefoot : surgical treatment and epidemiological aspects /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-054-1/.

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22

Chopra, M. S. "Some biochemical aspects of blood in rheumatoid arthritis and vascular diseases." Thesis, University of Strathclyde, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381360.

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23

Ho, Chun-wai Tom. "Social support as a predictor of the psychological adjustment of patients with rheumatoid arthritis in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B29725355.

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24

Pokorny, Ljubica. "Genetic markers of rheumatoid arthritis in a Western Cape black and coloured population." Thesis, Cape Technikon, 1996. http://hdl.handle.net/20.500.11838/1475.

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Thesis (Masters Degree( Medical Technology) --Cape Technikon, Cape Town,1996<br>Intensive investigations in many different populations over the last decade, have indicated a failure to understand the inheritance of rheumatoid arthritis (RA). It was hoped that genes within the class IT region of the major histocompatibility complex (MHq could shed some light on the inheritance of this autoimmune disease and which are now known without doubt, to confer susceptibility to the disease. Genetic studies of RA have concentrated primarily on its autoimmune nature and several investigations of

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25

Ernestam, Sofia. "Rheumatoid arthritis : pharmacological modulation of cytokines - aspects of clinical response and endocrine regulation /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-628-X/.

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26

Kastbom, Alf. "Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course." Doctoral thesis, Linköping : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-8618.

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27

Law, Wai-han, and 羅慧嫺. "Molecular mechanisms of arsenic trioxide in an in vitro model of rheumatoid arthritis synoviocyte." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41508531.

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28

Cheng, Ping-yuen, and 鄭秉源. "Association between tea drinking and markers of rheumatoid arthritis: a cross sectional study of baseline datafrom the Guangzhou biobank cohort study." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B3972394X.

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29

Lee, Sui Hong Philip, and 李瑞康. "An exploratory study of the effectiveness of meditation on patients with rheumatoid arthritis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31250075.

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30

Ångström, Lars. "Aerobic capacity in rheumatoid arthritis : aspects of associations with cardiovascular risk factors and disease activity." Licentiate thesis, Umeå universitet, Reumatologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-164592.

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Rheumatoid arthritis (RA) is a systemic and inflammatory disease that has been associated with an increased morbidity and mortality in cardiovascular disease (CVD). Low aerobic capacity is one of the strongest independent risk factors for CVD and all-cause mortality in the general population. In patients with longstanding RA, low aerobic capacity has been related with a worse cardiovascular profile and an increased risk of CVD mortality. As a consequence of this, low aerobic capacity might provide an additional risk factor for CVD in patients with RA. The aim of this thesis was to describe the

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31

Björk, Mathilda. "Aspects of Disability in Rheumatoid Arthritis : a five-year follow-up in the Swedish TIRA project." Doctoral thesis, Linköpings universitet, Rehabiliteringsmedicin, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11956.

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Rheumatoid arthritis (RA) is a progressive disease, often leading to disability. Because the disease course develops rapidly during the first years after diagnosis, more knowledge is needed about the early disease course to minimize later disability. This thesis describes the course of disability in early RA such as hand function, pain intensity, activity limitation and sick leave. In addition, this thesis compares disability between women and men and compares disability between RA patients and referents. This thesis is primarily based on data from the 320 patients that were included in the mu

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32

Eriksson, Catharina. "Immunological mechanisms in systemic autoimmunity : autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis." Doctoral thesis, Umeå universitet, Klinisk immunologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-42954.

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Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g., infliximab, a chimeric antibody targeting the pro-inflammatory cytokine TNF that has a central role in the inflammatory process in RA patients. Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease that may affect all organs and is characterized by a massive antibody production. Chemokines, chemokine receptors and lipoprotein receptor-related protein 1(CD91) ar

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33

Lombard, Louise Ann. "Body composition of rheumatoid arthritis patients and their perceptions and practices regarding diet, nutritional supplements and other treatments." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/17941.

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Thesis (MNutr)--Stellenbosch University, 2011<br>ENGLISH ABSTRACT: Introduction Rheumatoid Arthritis (RA) is a chronic, inflammatory, autoimmune disorder characterized by inflammation of the joints and surrounding tissue causing pain, swelling and stiffness. Studies suggest that aspects of the diet may alleviate symptoms and decrease the risk of complications. The scientific basis for a role of dietary therapy in RA has grown although there is still no consensus on the optimum diet. It has been shown that persons with RA tend to have a poor nutritional status; and rheumatoid cachexia, the

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34

Gerber, Roné. "Exploring the perceptions of women with rheumatoid arthritis of how their illness impacts their relationship with their intimate partner." Thesis, University of the Western Cape, 2006. http://hdl.handle.net/11394/2069.

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Magister Psychologiae - MPsych<br>This study explored women's perceptions of how their illness (Rheumatoid Arthritis- RA) affects their relationship with their intimate life partner. RA is a chronic, inflammatory, auto-immune illnes, which mainly affects the synovial membranes of multiple joints. This highly inflammatory poly-arthritis may lead to joint destruction, chronic pain, deformity and loss of functioning as unfortunate outcomes of the established illness. RA affects key life domains such as psychological well-being, social well-being, family and couple relationships, employment, loss

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35

Lin, Yan-kai, and 林欣佳. "Silencing of B cell activation factor gene and its implication in treating autoimmune arthritis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B45011370.

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36

Elramli, Amal. "Effectiveness of community based physical activity on step count and sedentary behaviour in people with rheumatoid arthritis within the first five years of diagnosis." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8491/.

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Background: Rheumatoid Arthritis (RA) is associated with increased risk of cardiovascular disease (CVD). Physical inactivity is a modifiable risk factors of CVD and frequently associated with impaired functional status and health related quality of life. Objectives: This single blind randomised controlled trial investigated the impact of a pedometer-supported walking and education programme (Walk for RA-WARA) on PA, sedentary time, PA self-efficacy, disease activity, functional capacity, quality of life and cardiovascular (CV) risk in people with RA. Methods: Seventy-six individuals, aged 56 (

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37

Cedergren, Jan. "Radical aspects on arthritis : the role of neutrophil generation of nitric oxide and superoxide in inflammatory conditions." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med984s.pdf.

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38

Olive, Colleen. "Molecular characterisation of the T-cell receptors expressed in rheumatoid arthritis patients." Phd thesis, 1993. http://hdl.handle.net/1885/143110.

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39

Roberts-Thomson, Peter J. "Low molecular weight IgM in health and disease / by Peter John Roberts-Thomson." 1987. http://hdl.handle.net/2440/38410.

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x, 156 leaves :<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (M.D.)--University of Adelaide, Dept. of Medicine, 1988

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40

Roberts-Thomson, Peter J. "Low molecular weight IgM in health and disease / by Peter John Roberts-Thomson." Thesis, 1987. http://hdl.handle.net/2440/38410.

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41

Penglis, Peter Savas. "The relationships between eicosanoid production and pro-inflammatory cytokines." Thesis, 2001. http://hdl.handle.net/2440/111707.

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Explores alternate strategies that may alter inflammatory cytokine production, particularly tumour necrosis factor α [tumor necrosis factor-alpha], and therefore provide a possible treatment for rheumatoid arthritis.<br>Thesis (Ph.D.) -- University of Adelaide, Dept. of Medicine, 2001

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42

Shirazi, Aida. "Nutrient intake of women with rheumatoid arthritis before and after receiving arthritis medication." Thesis, 1996. http://hdl.handle.net/1957/27438.

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We examined the nutrient intake of women with rheumatoid arthritis (RA) before and after initiation of treatment with arthritis medication. Results of past (before taking arthritis medication) and present diets of RA subjects were compared to the past and present diets of the non-RA group. Subjects with RA were 19 women with a mean age of 65 ± 9 years who were diagnosed with RA and were receiving arthritis medication on a regular basis. The non-RA subjects were 19 women with a mean age of 57 ± 3 years who were apparently healthy and were not taking any prescription medication. Both groups were

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43

Hodkinson, Bridget Dale. "Many hands that don't work: aspects of early rheumatoid arthritis." Thesis, 2013. http://hdl.handle.net/10539/12658.

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Objective: This study prospectively investigated disease activity, functional disability and health-related quality of life (HRQoL ) in South Africans with early RA, and sought predictors of clinical response at 12 months to traditional disease modifying anti-rheumatic drugs (DMARD) treatment. In addition, the relationships between disease activity, circulating cytokines, the presence of auto-antibodies, the shared epitope (SE), and rheumatoid nodules (RN) were explored. Methods: A cohort of 171 patients with early (≤ 2 years) RA who were DMARD-naïve at inception were prospectively assessed

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44

"Genetic associations of rheumatoid arthritis in Chinese." Thesis, 2011. http://library.cuhk.edu.hk/record=b6075400.

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Li, Martin.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2011.<br>Includes bibliographical references (leaves 187-208).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.

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45

Lewitton, Bertha. "Body image and anxiety as prognostic indicators in rheumatoid arthritis." Thesis, 2014. http://hdl.handle.net/10210/9902.

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M.A. (Clinical Psychology)<br>Rheumatoid arthritis, lithe great crippler" 1 has now established itself firmly in the category 'psychosomatic disease' and a psychosomatic approach is used when considering the aetiology of the disease and often the therapy and prognosis of the patient as well. The rehabilitation of the afflicted patient is the central concern of medical and para-medical personnel engaged in rheumatology. The patient's motivation for rehabilitation is generally considered to be the single most important factor affecting the rehabilitation process. The task of assessing this motiv

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46

Naidoo, Pamela. "The effects of coping, social support, attribution and cognitive illness representation on outcome measures of pain, disability and psychological well-being in rheumatoid arthritis patients." Thesis, 2002. http://hdl.handle.net/10413/3104.

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This study investigates the psychosocial aspects of rheumatoid arthritis (RA),a chronic debilitating disease. It explores the quality of life in a low socio-economic group of clinic-based adult RA patients. The aims of the study were as follows: (1) to assess the impact of both socio-demographic and psychosocial factors on RA health outcome, (2) to develop a multivariate, predictive model for RA, and (3) to assess the moderating role (or stress-reducing function) of psychosocial factors between the objective experience of RA and the subjective experience of RA. A sample of 186 RA patients with

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47

Van, Heerden Carlette. "The effect of aquatic therapy for rheumatoid and osteo arthritic sufferers." Thesis, 2012. http://hdl.handle.net/10210/5718.

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M.A.<br>As compared with psychoanalytic and other psychotherapies, behaviour therapy appears to have three distinct advantages. First of all, the treatment approach is precise. The target behaviours to be modified are specified, the methods to be used are clearly delineated, and the results can be readily evaluated (Marks, 1982). Second, the use of explicit learning principles is a sound basis for effective interventions as a result of their demonstrated scientific validity (Kazdin & Wilson, 1978). Third, the economy of time and costs is quite good. Not surprisingly, then, the overall outcomes

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48

Gerber, RonÃ©. "Exploring the perceptions of women with rheumatoid arthritis of how their illness impacts their relationship with their intimate partner." Thesis, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_1162_1189160666.

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<p>This study explored women's perceptions of how their illness (Rheumatoid Arthritis- RA) affects their relationship with their intimate life partner. RA is a chronic, inflammatory, auto-immune illnes, which mainly affects the synovial membranes of multiple joints. This highly inflammatory poly-arthritis may lead to joint destruction, chronic pain, deformity and loss of functioning as unfortunate outcomes of the established illness. RA affects key life domains such as psychological well-being, social well-being, family and couple relationships, employment, loss of independence and restriction

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