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1

Yoshii, I. "AB0271 EFFECTIVENESS OF DULOXETINE FOR RELIEF OF THE REMNANT PAIN OF RHEUMATOID ARTHRITIS PATIENT WHOSE DISEASE ACTIVITY IS REMISSION." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1434.1–1434. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1370.

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Background:Pain control in rheumatoid arthritis (RA) patient is an important matter. When pain remains even disease activity is remission, it causes deterioration of activity in daily living (ADL) in past research. In other words, pain affects ADL independently from disease activity, namely the Health Assessment Questionnaire (HAQ) score, a most popular index of ADL for patient with RA[1]. Thus, burden of remnant pain despite clinical remission in RA is serious and pending subject.Duloxetine, a potent reuptake inhibitor of serotonin and norepinephrine, is developed for the treatment of major d
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2

&NA;. "Methylprednisolone infusion works well in refractory rheumatoid arthritis." Inpharma Weekly &NA;, no. 748 (1990): 10. http://dx.doi.org/10.2165/00128413-199007480-00026.

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3

Kesmen, H., A. K. Cengiz, A. Bilgici, G. Alayli, and D. Durmus. "FRI0616-HPR SOCIAL SUPPORT WORKS BETTER IN RHEUMATOID ARTHRITIS THAN FIBROMYALGIA." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 913.3–913. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5673.

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Background:Social support is defined as a helpful resource that can meet an individual’s urgent needs and is provided by a network of others, such as family members, friends, colleagues and other communities. Perceived social support (PSS) is the subjective support that individuals may experience, emphasizing the individual’s self-understanding, experience and feelings of social support from different sources. Social support directly exerts beneficial effects on the health-related quality of life in rheumatoid arthritis and fibromyalgia patients.Objectives:The aim of this study is to compare t
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4

van de Loo, Fons A. J., Jeroen Geurts, and Wim B. van den Berg. "Gene therapy works in animal models of rheumatoid arthritis so what!" Current Rheumatology Reports 8, no. 5 (2006): 386–93. http://dx.doi.org/10.1007/s11926-006-0070-y.

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5

Mullaikodi O and Komala M. "Herbal Remedies: Promisingly Effective for Rheumatoid Arthritis." International Journal of Research in Pharmaceutical Sciences 12, no. 1 (2021): 456–61. http://dx.doi.org/10.26452/ijrps.v12i1.4090.

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Rheumatoid arthritis is most significant and devastating to the human body. It is an autoimmune disorder that affects almost 2-4% of the population of the world. Rheumatoid arthritis usually occurs when the immune system works against one’s own body and attacks it. Rheumatoid arthritis generally affects the joints like wrists, elbows, knees and ankles. Even though the reason for causing RA is unknown, the contributing factors for the development of the RA are of various types. Usually women are more affected by RA then men due to the prevalence of hormonal changes. Age is also an important fac
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6

SINGH, ABHA G., SIDDHARTH SINGH, and PREET PAUL SINGH. "YouTube for Information on Rheumatoid Arthritis — A Wakeup Call?" Journal of Rheumatology 39, no. 5 (2012): 899–903. http://dx.doi.org/10.3899/jrheum.111114.

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Objective.Rheumatoid arthritis (RA) is a common debilitating autoimmune disease, with unmet need for knowledge among patients and the general population. YouTube is a popular, consumer-generated, video-sharing website, which can be a source of information on RA. We investigated the quality of information on RA on YouTube and analyzed audience interaction.Methods.YouTube was searched using the term “Rheumatoid Arthritis,” for videos uploaded on RA. Two physicians independently classified videos as useful, misleading, or patient views, and rated them on a 5-point global quality scale (GQS; 1 = p
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Jones, Graeme, and Changhai Ding. "Tocilizumab: A Review of Its Safety and Efficacy in Rheumatoid Arthritis." Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 3 (January 2010): CMAMD.S4864. http://dx.doi.org/10.4137/cmamd.s4864.

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Recent years have seen many exciting developments in the treatment of rheumatoid arthritis. Tocilizumab (TCZ) is a monoclonal antibody which inhibits the interleukin-6 receptor. After initial studies in Japan, it has been extensively studied in five multicentre clinical trials. This report summarises the key efficacy and toxicity findings from the major clinical trials. TCZ works quickly and effectively in rheumatoid arthritis either as monotherapy or in combination with other agents in early disease, DMARD inadequate responders, seronegative disease and after anti-TNF failure. The toxicity pr
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8

Faris, P. P. Muhamed, K. Sreejith, B. Athulnadh, K. V. Musaina Thasneem, Cherakkulath C. Neena, and Namitha Maniyan. "A Review on Comparison of Effectiveness and Safety of Disease Modifying Anti-Rheumatoid Drugs Used in Patients with Rheumatoid Arthritis." Journal of Drug Delivery and Therapeutics 10, no. 6 (2020): 207–12. http://dx.doi.org/10.22270/jddt.v10i6.4535.

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Objective: To compare the safety and effectiveness of monotherapy as well as combination therapy with disease modifying anti rheumatoid drugs (DMARDs) in rheumatoid arthritis patients.
 Data sources: Study works limited to the English language and more concentrated to adults by using Google Scholar, PubMed and The Cochrane library.
 Summary: Some head to head trial works, retrospective studies and prospective cohort studies were used to compare the safety and effectiveness of the therapy. Here we go through the comparison in between each disease modifying anti rheumatoid drug (DMARD)
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9

Werneke, Ursula. "A Lively Mind in a Frozen Body." Journal of Evidence-Based Complementary & Alternative Medicine 16, no. 3 (2011): 233–38. http://dx.doi.org/10.1177/2156587211414425.

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“Rickety Kate” was the descriptive name of Minnie Agnes Filson, a popular Australian poet featured widely in the Australian media from the 1930s through to the 1960s. The assumed name was a reflection of her severe rheumatoid arthritis, which left her completely immobilized. During her lifetime, Kate received a variety of conventional medical treatments, which proved largely ineffective. She finally turned to an Indian healer, who managed to improve her quality of life although her physical disabilities persisted. This article explores the history of rheumatoid arthritis from a patient’s persp
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10

Skiba, Meghan B., Laura L. Hopkins, Allison L. Hopkins, Dean Billheimer, and Janet L. Funk. "Nonvitamin, Nonmineral Dietary Supplement Use in Individuals with Rheumatoid Arthritis." Journal of Nutrition 150, no. 9 (2020): 2451–59. http://dx.doi.org/10.1093/jn/nxaa197.

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ABSTRACT Background Over-the-counter, natural product–based (nonvitamin, nonmineral) dietary supplement (NVNM DS) use is common in adults with rheumatoid arthritis (RA), a group at risk for drug-DS interactions, due to polypharmacy, but this use is underreported to health care providers. Recent dramatic changes in US sales of specific NVNM DS suggest that the prevalence and types of NVNM DS used in RA populations may also have shifted. Objectives A study was undertaken to identify current and past use of specific NVNM DS for RA disease treatment and to examine associations between use of NVNM
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11

Ishikawa, Yuki, and Chikashi Terao. "The Impact of Cigarette Smoking on Risk of Rheumatoid Arthritis: A Narrative Review." Cells 9, no. 2 (2020): 475. http://dx.doi.org/10.3390/cells9020475.

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Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent proliferation of synovial tissues, which eventually leads to cartilage and bone destruction without effective treatments. Anti-citrullinated cyclic peptide/protein antibody (ACPA) and rheumatoid factor (RF) are two main characteristic autoantibodies found in RA patients and are associated with unfavorable disease outcomes. Although etiologies and causes of the disease have not been fully clarified yet, it is likely that interactive contributions of genetic and environmental factors play a ma
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12

Venkatesha, Shivaprasad H., Rajesh Rajaiah, Brian M. Berman, and Kamal D. Moudgil. "Immunomodulation of Autoimmune Arthritis by Herbal CAM." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–13. http://dx.doi.org/10.1155/2011/986797.

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Rheumatoid arthritis (RA) is a debilitating autoimmune disease of global prevalence. The disease is characterized by synovial inflammation leading to cartilage and bone damage. Most of the conventional drugs used for the treatment of RA have severe adverse reactions and are quite expensive. Over the years, increasing proportion of patients with RA and other immune disorders are resorting to complementary and alternative medicine (CAM) for their health needs. Natural plant products comprise one of the most popular CAM for inflammatory and immune disorders. These herbal CAM belong to diverse tra
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13

Credè, William B., and Walter J. Hierholzer. "Analytic Strategies in Hospital Epidemiology: Cross-Sectional Studies." Infection Control & Hospital Epidemiology 10, no. 7 (1989): 321–25. http://dx.doi.org/10.1086/646036.

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The cross-sectional study, also called the prevalence survey, is one of the most popular epidemiologic methods. It has been employed in up to one-third of published studies. This survey method has two primary applications: describing population characteristics and analyzing potential etiologic agents or risk tactors for diseases or other population attributes. Studies of the prevalence of rheumatoid arthritis and the association between smoking and chronic bronchitis are two examples of the cross-sectional method applied at the population-based level.
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14

Peluso, Rosario, Matteo Nicola Dario Di Minno, Salvatore Iervolino, et al. "Enteropathic Spondyloarthritis: From Diagnosis to Treatment." Clinical and Developmental Immunology 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/631408.

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Enteropathic arthritis (EA) is a spondyloarthritis (SpA) which occurs in patients with inflammatory bowel diseases (IBDs) and other gastrointestinal diseases. Diagnosis is generally established on the medical history and physical examination. It was, generally, made according to the European Spondyloarthropathy Study Group (ESSG) criteria. Rheumatic manifestations are the most frequent extraintestinal findings of IBD with a prevalence between 17% and 39%, and IBD is associated, less frequently, with other rheumatic disease such as rheumatoid arthritis, Sjogren syndrome, Takayasu arteritis, and
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15

Sciascia, Savino, Massimo Radin, Irene Cecchi, et al. "Tailoring Tofacitinib Oral Therapy in Rheumatoid Arthritis: The TuTORApp—A Usability Study." International Journal of Environmental Research and Public Health 17, no. 10 (2020): 3469. http://dx.doi.org/10.3390/ijerph17103469.

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Objective: To create a mobile application able to help patients follow medical treatments properly. Methods: We designed and developed a custom Android/iOS App to remind patients of the pharmaceutical drugs to be taken, of the visits and exams to attend, and to detect their compliance with their personal therapeutic plan. In this paper we describe the App development, UX/UI design, Gamification. TuTOR is an Android and iOS application designed to remind patients of the drugs to be taken, giving them all the information related to their therapeutic plans in a simple and non-invasive way. Thanks
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16

Ugolini, Alessio, and Marianna Nuti. "Rheumatoid Factor: A Novel Determiner in Cancer History." Cancers 13, no. 4 (2021): 591. http://dx.doi.org/10.3390/cancers13040591.

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The possible interplay between autoimmunity and cancer is a topic that still needs to be deeply explored. Rheumatoid factors are autoantibodies that are able to bind the constant regions (Fc) of immunoglobulins class G (IgGs). In physiological conditions, their production is a transient event aimed at contributing to the elimination of pathogens as well as limiting a redundant immune response by facilitating the clearance of antibodies and immune complexes. Their production can become persistent in case of different chronic infections or diseases, being for instance a fundamental marker for th
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17

SHARPE, LOUISE. "Psychological Treatment for Rheumatoid Arthritis Works: Now We Need to Know What Elements Are Most Effective and for Whom." Journal of Rheumatology 40, no. 11 (2013): 1788–90. http://dx.doi.org/10.3899/jrheum.131043.

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18

Scardapane, A., L. Breda, M. Lucantoni та F. Chiarelli. "TNF-αPolymorphisms in Juvenile Idiopathic Arthritis: Which Potential Clinical Implications?" International Journal of Rheumatology 2012 (2012): 1–16. http://dx.doi.org/10.1155/2012/756291.

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Whether tumor necrosis factor alpha (TNF-α) gene polymorphisms (SNPs) influence disease susceptibility and treatment of patients with juvenile idiopathic arthritis (JIA) is presently uncertain. TNF-αis one of the most important cytokine involved in JIA pathogenesis. Several single nucleotide polymorphisms (SNPs) have been identified within the region of the TNF-αgene but only a very small minority have proven functional consequences and have been associated with susceptibility to JIA. An association between some TNF-αSNPs and adult rheumatoid arthritis (RA) susceptibility, severity and clinica
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19

Yeung, Winnie Wan-Yin, and Chak-Sing Lau. "Mesenchymal Stem Cell Therapy for rheumatic diseases." Hong Kong Bulletin on Rheumatic Diseases 16, no. 1 (2016): 6–10. http://dx.doi.org/10.1515/hkbrd-2016-0002.

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AbstractMesenchymal stem cell therapy (MSCT) is an innovative treatment for rheumatic diseases. Underlying mechanism of how MSCT works in rheumatic diseases are still uncertain and with various hypotheses. Animal studies in MSCT show conflicting results mainly attributed by the differences in administration methods of MSCT, types of MSC use and randomization procedures. Human studies of MSCT are so far small scale but with satisfactory results in patients with systemic lupus erythematosus (SLE). Human studies of MSCT, however, showed less rewarding results in patients with rheumatoid arthritis
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20

Tongshuwar, G. T., A. O. Ojetunde, A. F. Oyegoke, and T. Oyegoke. "ETHNO-BOTANICAL SURVEY OF PLANTS USED IN A RHEUMATOID ARTHRITIS TREATMENT: A CASE STUDY OF JOS IN NIGERIA." Medical Science of Ukraine (MSU) 16, no. 4 (2020): 35–45. http://dx.doi.org/10.32345/2664-4738.4.2020.6.

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Relevance. Rheumatoid arthritis (RA) is an autoimmune disorder leading to the inflammation of the joints. This inflammation finds expression in the lining of the synovial tissues causing swellings and severe pains and deterioration of the bone in the long run. This disease's exact etiology is not yet to be ascertained; however, there are claims of the interplay of genetic and environmental factors. RA is one of the diseases ravaging the people of Jos in Nigeria, owing to the high cost of orthodox medicine.
 Objective. The study was carried out to collect information and find out plants us
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21

Udachkina, E. V., D. S. Novikova, T. V. Popkova, et al. "PROGRESSION OF CAROTID ARTERY ATHEROSCLEROSIS DURING TREATMENT TO TARGET IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS." Rheumatology Science and Practice 56, no. 4 (2018): 449–55. http://dx.doi.org/10.14412/1995-4484-2018-449-455.

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Rheumatoid arthritis (RA) is a disease with a high cardiovascular risk. The results of works on the impact of antirheumatic therapy on carotid artery (CA) intima-media thickness (IMT) are contradictory. Objective: to assess the time course of changes in CA IMT and CA atherosclerosis (CAA) in patients with early RA during treatment to target at a 18-month follow-up. Subjects and methods. The investigation enrolled patients with early RA (disease duration of less than 12 months), who had not previously taken disease-modifying antirheumatic drugs and glucocorticoids. Duplex scanning (DS) of the C
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Singh, Harvinder, and Joseph J. Dias. "Surface replacement arthroplasty of the proximal interphalangeal and metacarpophalangeal joints: The current state." Indian Journal of Plastic Surgery 44, no. 02 (2011): 317–26. http://dx.doi.org/10.1055/s-0039-1699508.

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ABSTRACTSurface replacement arthroplasty for proximal interphalangeal joint and metacarpophalangeal joints are becoming popular. Low profile, anatomically designed implants limit the amount of bone removed but need preservation of the collateral ligaments. Pyrocarbon and cobalt-chrome stemmed unconstrained implants on ultra-high molecular weight polyethylene are the two commonly available bearing surfaces. The indications for small joint arthroplasty are degenerative, post-traumatic or rheumatoid arthritis. Early results are encouraging, primarily in patient satisfaction and pain relief, but a
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Karateev, A. E. "The therapeutic potential of etoricoxib in clinical practice." Modern Rheumatology Journal 14, no. 1 (2020): 108–17. http://dx.doi.org/10.14412/1996-7012-2020-1-108-117.

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Etoricoxib is one of the most popular representatives of a group of nonsteroidal anti-inflammatory drugs (NSAIDs), which is widely used in Russia and other countries of the world. It is a highly selective cyclooxygenase 2 inhibitor that has a rapid and pronounced analgesic effect, a high antiinflammatory potential, and an ability to affect the development of central sensitization, one of the central mechanisms for chronic pain. The therapeutic potential and safety of etoricoxib have been extensively tested in numerous large-scale randomized controlled trials (RCTs). It has proven to be an effe
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Wang, Tian, Xiaolin Sun, Jing Zhao, et al. "Regulatory T cells in rheumatoid arthritis showed increased plasticity toward Th17 but retained suppressive function in peripheral blood." Annals of the Rheumatic Diseases 74, no. 6 (2014): 1293–301. http://dx.doi.org/10.1136/annrheumdis-2013-204228.

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ObjectiveRegulatory T cells (Tregs) with the plasticity of producing proinflammatory cytokine IL-17 have been demonstrated under normal and pathogenic conditions. However, it remains unclear whether IL-17-producing Tregs lose their suppressive functions because of their plasticity toward Th17 in autoimmunity. The aim of this study was to investigate IL-17-producing Tregs from patients with rheumatoid arthritis (RA), and characterise their regulatory capacity and clinical significance.MethodsFoxp3 and IL-17 coexpression were evaluated in CD4 T lymphocytes from RA patients. An in vitro T cell po
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Salaffi, F., M. Tardella, M. Carotti, M. DI Carlo, and A. Giovagnoni. "SAT0101 ABATACEPT IN RHEUMATOID ARTHRITIS ASSOCIATED-INTERSTITIAL LUNG DISEASE: SHORT TERM OUTCOME AND PROGNOSTIC FACTORS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 984.2–984. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2778.

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Background:The prevalence of interstitial lung disease (ILD) in rheumatoid arthritis (RA) varies in the medical literature from 1% to 67% and is a major cause of mortality. Previous works have identified increased age, smoking and anticytrullinated protein antibodies (ACPA) titre as risk factors for RA-ILD (RA-ILD). Conventional treatments for RA may lead to a new onset or worsening of RA-ILD, so treatment should be identified to prevent the onset or exacerbation of RA-ILD. Studies have shown that abatacept (ABA) may improve the outcome of RA-ILD.Objectives:The aim of our study is to evaluate
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26

Karateev, A. E. "ETODOLAC, A WELL KNOWN AND ACTIVELY USED DRUG IN DIFFERENT COUNTRIES OF THE WORLD. WOULD IT BE TIME FOR US?" Rheumatology Science and Practice 57, no. 4 (2019): 468–73. http://dx.doi.org/10.14412/1995-4484-2019-468-473.

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Etodolac is a nonsteroidal anti-inflammatory drug (NSAID), a moderately selective cyclooxygenase-2 inhibitor, which has been already used in clinical practice for more than 30 years as a universal analgesic and anti-inflammatory agent. Etodolac has proven itself in relieving acute pain associated with injuries and surgical interventions (particularly in dentistry). However, the main point of application of etodolac is long-term pain control in chronic rheumatic diseases, such as osteoarthritis and rheumatoid arthritis. Numerous clinical trials have shown that etodolac is at least not inferior
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27

Daneshwari S Kanashetti, Byadgi P S, and Dwivedi K N. "A Randomised Clinical trial evaluating effectiveness of Guduchi and Shunthi kvatha in Amavata(Rheumatoid arthritis) in comparison with Indomethacin." International Journal of Research in Pharmaceutical Sciences 11, no. 2 (2020): 1936–43. http://dx.doi.org/10.26452/ijrps.v11i2.2111.

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Indian Traditional system of medicine (Ayurveda) has played premier role in the management of crippling disease, Amavata is one among them. Amavata is a chronic disease caused by vitiation of Vata associated with Ama. The clinical presentation closely mimic Rheumatoid arthritis in accordance with their similarities in clinical features like pain, swelling, stiffness, fever, general debility, fatigue is almost identical to that of Amavata. Herbal drugs are becoming increasingly popular in managing chronic diseases because of its safety, long term usage with fewer side effect and multidimensiona
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Bobos, Pavlos, Joy MacDermid, Christina Ziebart, et al. "Barriers, facilitators, preferences and expectations of joint protection programmes for patients with hand arthritis: a cross-sectional survey." BMJ Open 11, no. 1 (2021): e041935. http://dx.doi.org/10.1136/bmjopen-2020-041935.

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ObjectivesThe objective of this survey was to investigate the barriers, facilitators, expectations and patient preferences regarding joint protection (JP) programmes in people with hand arthritis.DesignCross-sectional survey.SettingTertiary clinic.ParticipantsPatients with hand arthritis: osteoarthritis, rheumatoid arthritis, psoriatic arthritis and other forms of arthritis.Primary and secondary outcome measuresThis study used a survey among people with hand arthritis. Descriptive statistics and percentages were reported for all the data about the barriers, facilitators and preferences around
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Kaur, Ranjit, Kamaldeep Kaur, Aditya Khamparia, and Divya Anand. "An Improved and Adaptive Approach in ANFIS to Predict Knee Diseases." International Journal of Healthcare Information Systems and Informatics 15, no. 2 (2020): 22–37. http://dx.doi.org/10.4018/ijhisi.2020040102.

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Artificial intelligence is emerging as a persuasive tool in the field of medical science. This research work also primarily focuses on the development of a tool to automate the diagnosis of inflammatory diseases of the knee joint. The tool will also assist the physicians and medical practitioners for diagnosis. The diseases considered for this research under inflammatory category are osteoarthritis, rheumatoid arthritis and osteonecrosis. A five-layer adaptive neuro-fuzzy (ANFIS) architecture was used to model the system. The ANFIS system works by mapping input parameters to the input membersh
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DYDYKINA, I. S., P. S. DYDYKINA, and E. L. NASONOV. "GENNO-INZhENERNYE BIOLOGIChESKIE PREPARATY V TERAPII OSTEOPOROZA U BOL'NYKhREVMATOIDNYM ARTRITOM." Osteoporosis and Bone Diseases 16, no. 2 (2013): 12–17. http://dx.doi.org/10.14341/osteo2013212-17.

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The authors review the current literature data on the influence of the genetically engineered biological drugs on the bone mineral density, bone exchange and remodeling of bone are submitted. Due to high efficiency these drugs received the deserved popularity in spite of the fact that are applied in rheumatology rather recently. The leading role in pathogenesis of local and generalized bone resorption and destruction in rheumatoid arthritis is realized by mediators of immune and inflammatory processes (pro-inflammatory cytokinins): tumor necrosis factor a, interleukin 1, 2, 12, 17, interferon
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Gridneva, G. I., E. S. Aronova, V. S. Sygyrta, A. V. Kudryavtseva, and K. S. Nurbaeva. "What do we know about the possibility of predicting the potential efficacy and safety of methotrexate, by measuring the concentration of its metabolites in rheumatoid arthritis?" Modern Rheumatology Journal 14, no. 3 (2020): 146–49. http://dx.doi.org/10.14412/1996-7012-2020-3-146-149.

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Rheumatoid arthritis (RA) is characterized by a progressive course with the formation of joint deformities and the development of severe functional disorders. The most favorable conditions for changing the course of the disease emerge in the first months after its onset. Methotrexate (MTX) occupies a leading position in the treatment of RA. There is a need to develop tools that will be able to predict the efficacy and tolerability of MTX at the earliest stages of RA treatment. The concentration of active metabolites of MTX is considered as a potential biomarker that enables one to predict what
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Izumi, K., K. Suzuki, M. Hashimoto, et al. "AB1103 AUTOMATIC FINGER JOINT BONE EROSION SCORE PREDICTION CONSIDERING 2-TIME-POINT X-RAYS OF PATIENTS WITH RHEUMATOID ARTHRITIS BY DEEP LEARNING." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1840.1–1841. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4107.

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Background:Medical image analysis using deep learning (DL) has been attracting attention. In previous research, we proposed a DL method for detection of joint region and evaluation for bone destruction at a single point in time in hand X-rays of patients with rheumatoid arthritis (RA) [1-2]. However, in the score of van der Heijde-modified total Sharp scores (mTSS) in X-rays, it is difficult to apply the method as it is. In mTSS, score difference between 2-time points is important, and there is a problem that the score at each time varies depending on the doctor who evaluates.Objectives:We aim
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Yoshii, I. "AB0101 THE IMPACT OF TIME SPAN TO ACHIEVE BOOLEAN REMISSION FOR MAINTAINING DISEASE ACTIVITY AFTER ACQUISITION IN RHEUMATOID ARTHRITIS PATIENT." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1079.1–1079. http://dx.doi.org/10.1136/annrheumdis-2021-eular.297.

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Background:Boolean remission criteria is one most popular and stringent criteria in treating patient with rheumatoid arthritis (RA), because it may guarantees a stable clinical course after attaining remission.Objectives:Impact of time span from initiation to achieving Boolean remission on maintaining disease activity, daily activities, and quality of life after attaining Boolean remission was investigated from daily clinical practice data.Methods:685 patients with RA since August 2010 under the T2T strategy were treated. They were monitored for their TJC, SJC, PGA, EGA, CRP, and disease activ
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Bartikoski*, B., J. Miranda de Souza Silva, E. Chiela, and R. Xavier. "AB0086 NEW METHOD TO ASSESS SKELETAL MUSCLE ATROPHY IN COLLAGEN INDUCED ARTHRITIS (CIA) MODEL." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1343.2–1343. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5995.

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Background:Muscle quality in rheumatoid arthritis (RA) is a new concept that involves morphological features and function. A measurement that associates cell morphology with clinical and physical parameters has not been reported in the literature. CIA is a RA mice model characterized by loss of muscle mass similar to human RA, thereby it is a convenient model to study the disease impact in muscle physiology.Objectives:Develop an index to measure the morphometry of muscle fibers and correlate the morphological features with the muscle functional performance in CIA.Methods:18 DBA/1J mice were in
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Morsoleto, M. J. M. S., E. M. I. Amstalden, F. M. R. Morgado, and M. B. Bértolo. "Evaluation of biological agent association anti-TNF induced arthritis and laser therapy: an experimental study." Microscopy and Microanalysis 19, S4 (2013): 61–62. http://dx.doi.org/10.1017/s1431927613000925.

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Rheumatoid arthritis is a chronic, systemic inflammatory illness that predominantly affects the joints. Recent works tested inductor agents of arthritis models and their effects when associated to low intensity laser therapy. In this work the effects of the biological agent Infliximab and low intensity laser therapy were investigated in an animal experimental model of Zymosan induced arthritis. This model is widely used in pharmacological studies because it enhances the hypernociception of inflammation, detected throughout the observation of joint articular incapacitation, increase of vascular
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Savaringal, Jayan Pariyani, and Lally M. S. "Anti inflammatory effect of rhizome of Curcuma longa. Linn, in Albino rats by the method of Carrageenin induced paw oedema." International Journal of Basic & Clinical Pharmacology 7, no. 2 (2018): 229. http://dx.doi.org/10.18203/2319-2003.ijbcp20180032.

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Background: Curcuma longa or turmeric is a popular Ayurvedic herb, traditionally used for various inflammatory conditions including rheumatoid arthritis and spondylitis. Turmeric which containing phytochemical ingredient curcumin is used in India for centuries as a topical anti inflammatory agent. Many of the currently used anti inflammatory agents like NSAID’s and glucocorticoids have many undesirable adverse effects, especially when they are used for long period. In the present study, Curcuma longa, a plant belonging to the Zingiberaceae family was chosen for investigating its anti-inflammat
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Weng, Shu-Wen, Bor-Chyuan Chen, Yu-Chiao Wang, et al. "Traditional Chinese Medicine Use among Patients with Psoriasis in Taiwan: A Nationwide Population-Based Study." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/3164105.

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Traditional Chinese medicine (TCM) has long been used for patients with psoriasis. This study aimed to investigate TCM usage in patients with psoriasis. We analyzed a cohort of one million individuals representing the 23 million enrollees randomly selected from the National Health Insurance Research Database in Taiwan. We identified 28,510 patients newly diagnosed with psoriasis between 2000 and 2010. Among them, 20,084 (70.4%) patients were TCM users. Patients who were female, younger, white-collar workers and lived in urbanized area tended to be TCM users. The median interval between the ini
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Lan, Ching, Ssu-Yuan Chen, Jin-Shin Lai, and Alice May-Kuen Wong. "Tai Chi Chuan in Medicine and Health Promotion." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–17. http://dx.doi.org/10.1155/2013/502131.

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Tai Chi Chuan (Tai Chi) is a Chinese traditional mind-body exercise and recently, it becomes popular worldwide. During the practice of Tai Chi, deep diaphragmatic breathing is integrated into body motions to achieve a harmonious balance between body and mind and to facilitate the flow of internal energy (Qi). Participants can choose to perform a complete set of Tai Chi or selected movements according to their needs. Previous research substantiates that Tai Chi has significant benefits to health promotion, and regularly practicing Tai Chi improves aerobic capacity, muscular strength, balance, h
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Wu, Honglong, Lihua Cai, Dongfang Li, et al. "Metagenomics Biomarkers Selected for Prediction of Three Different Diseases in Chinese Population." BioMed Research International 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/2936257.

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The dysbiosis of human microbiome has been proven to be associated with the development of many human diseases. Metagenome sequencing emerges as a powerful tool to investigate the effects of microbiome on diseases. Identification of human gut microbiome markers associated with abnormal phenotypes may facilitate feature selection for multiclass classification. Compared with binary classifiers, multiclass classification models deploy more complex discriminative patterns. Here, we developed a pipeline to address the challenging characterization of multilabel samples. In this study, a total of 300
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Lambertini, Elisabetta, Letizia Penolazzi, Giulia Pellielo, et al. "Pro-Osteogenic Properties of Violina pumpkin (Cucurbita moschata) Leaf Extracts: Data from In Vitro Human Primary Cell Cultures." Nutrients 13, no. 8 (2021): 2633. http://dx.doi.org/10.3390/nu13082633.

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Traditional medicines rely mainly on use of plant extracts to mitigate or treat a wide range of disorders, including those that affect skeletal homeostasis. In this study, we investigated for the first time the potential pro-osteogenic effects of hexane, acetone and methanol extracts of the leaves of Cucurbita moschata, a very popular pumpkin cultivar in Western countries. We found that in Cucurbita moschata leaves, there are acetone-extractable substances—in particular, fatty acids such as 13-OH-9Z,11E,15E-octadecatrienoic acid (PU-13OH-FA), which is capable of both stimulating the function o
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Narendra, Shivani, Anitha Roy, Rajeshkumar Shanmugam, and Lakshmi Thangavelu. "Anti-inflammatory activity of nutmeg oleoresin mediated silver nanoparticles- An In- vitro study." Biomedicine 39, no. 2 (2020): 234–38. http://dx.doi.org/10.51248/.v39i2.186.

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Introduction and Aim: The most emerging area of research in nanotechnology deals with the synthesis of nanoparticles which are of great importance due to its use in various biological fields. Myristica fragrans is commonly known as “nutmeg”. It is popular as a spice and also possesses various therapeutic properties. It has a characteristic pleasant fragrance and a slightly warm taste. It has various therapeutic uses and is widely used. The aim is to assess the anti-inflammatory activity of nutmeg oleoresin mediated silver nanoparticles.
 Materials and Methods: The nutmeg oleoresin mediate
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Carlson, Linda E. "Mindfulness-Based Interventions for Physical Conditions: A Narrative Review Evaluating Levels of Evidence." ISRN Psychiatry 2012 (November 14, 2012): 1–21. http://dx.doi.org/10.5402/2012/651583.

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Research on mindfulness-based interventions (MBIs) for treating symptoms of a wide range of medical conditions has proliferated in recent decades. Mindfulness is the cultivation of nonjudgmental awareness in the present moment. It is both a practice and a way of being in the world. Mindfulness is purposefully cultivated in a range of structured interventions, the most popular of which is mindfulness-based stress reduction (MBSR), followed by mindfulness-based cognitive therapy (MBCT). This paper begins with a discussion of the phenomenological experience of coping with a chronic and potentiall
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Borba, Elizabeth Regina de Castro, Haymê dos Santos Ferreira, Thiago Castro Mubárack, et al. "Technological prospection of the biological activities of Plectranthus amboinicus (Loureiro) Sprengel: an integrative review." Research, Society and Development 10, no. 5 (2021): e30110514653. http://dx.doi.org/10.33448/rsd-v10i5.14653.

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Plectranthus amboinicus (Loureiro) Sprengel is popularly known as malvariço or indian borage. This paper carries out the technological prospecting of this species with an emphasis on its biological activities. The research consisted of an integrative literature review based on information collected from patent and electronic databases. Initially, 3019 results were obtained, which, after the screening, selection and analysis process, resulted in 55 articles and 48 patent documents. It was found that 77.08% (n=37) of patent deposits refer to obtaining or improving the process and 22.92% (n=11) t
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Bogmat, L. F., A. A. Fadieieva, and N. S. Shevchenko. "Quality of life problems in children with juvenile idiopathic arthritis and its subtype associated with uveitis (literature review and own research)." CHILD`S HEALTH 16, no. 4 (2021): 270–78. http://dx.doi.org/10.22141/2224-0551.16.4.2021.236904.

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Background. The problem of the quality of life (QoL) is relevant nowadays, especially for patients with chronic diseases, including juvenile idiopathic arthritis (JIA) and the subtype of JIA associated with uveitis (JIA-u). The purpose was to carry out a literature review on the QoL in children with JIA and JIA-u, with an analysis of existing tools, the possibility of their use in children, and to assess the QoL indicators of children with JIA, who were treated in a specialized department of the hospital. Materials and methods. The search was performed in the PubMed, Medline, and Google databa
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Cipriani, P., P. DI Benedetto, P. Ruscitti, et al. "THU0073 THE ANTI-ANGIOGENIC ROLE OF TOFACITINIB DURING EXPERIMENTAL MODEL OF ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 249–50. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3486.

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Background:During rheumatoid arthritis (RA), a chronic autoimmune disease, the loop existing between inflammation and angiogenesis, characterised by new vessels formation associated with the increased recruitment of inflammatory cells, via the abnormal neo-angiogenesis in the synovial tissues, is considered an early important pathogenic mechanism.Tofacitinib, a potent and selective JAK inhibitor, showed a good profile of safety and efficacy in RA patients, slowing the radiographic progression of the disease. In the last years, many works confirmed that some pro-angiogenic genes are targets of
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Guerrero, Angel. "A2A Adenosine Receptor Agonists and their Potential Therapeutic Applications. An Update." Current Medicinal Chemistry 25, no. 30 (2018): 3597–612. http://dx.doi.org/10.2174/0929867325666180313110254.

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Background: Adenosine is an endogenous purine nucleoside, which mediates a variety of important biological processes and diseases, such as vasodilation, inflammation, cancer, wound healing, ischemia reperfusion injury, Parkinson disease, infectious diseases, and other CNS disorders. Particularly important are the A2A receptors that have been expressed in the lung, liver, heart, cardiovascular tissues, leukocytes, neutrophils, and endothelial cells. This review provides an update of the latest A2A receptor agonists developed in the period 2005-2017, their selectivity regarding other adenosine r
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Probasco, William V., Ryan Lee, Danny Lee, Lawal Labaran, and Benjamin E. Stein. "Complications Associated with Total Ankle Arthroplasty vs Ankle Arthrodesis." Foot & Ankle Orthopaedics 4, no. 4 (2019): 2473011419S0034. http://dx.doi.org/10.1177/2473011419s00349.

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Category: Ankle, Ankle Arthritis Introduction/Purpose: While ankle arthrodesis (AA) has long been considered the gold standard treatment for ankle arthritis, total ankle arthroplasty (TAA) has become increasingly popular with improving implant designs. Although AA is currently performed more frequently than TAA, it has been associated with increased pain/degeneration, and loss of function in adjacent joints of the foot. Contrastingly, TAA has been suggested to preserve motion of the ankle while reducing the stress imposed on other areas of the foot. However, it has been questioned whether TAA
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Bridgewood, C., K. Sharif, H. Rowe, T. Russell, and D. Mcgonagle. "SAT0358 A ROLE FOR IL-4 AND IL-13 IN MODULATING THE IL-23/IL-17 AXIS IN ENTHESITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1126.2–1126. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5533.

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Background:IL-4 and IL-13 are related Th2 cytokines, with documented roles in allergic inflammation such as atopic dermatitis (AD). Psoriatic Arthritis (PsA) is typically thought to be a result of Th1/Th17 driven response, and blockage of this pathway (IL-23, IL-17 and TNF) has proven successful. Despite this, there is a strong genetic risk association for IL-13 and PsA(1), however, the precise role of IL-13 in PsA is presently unknown. The enthesis is the region where tendons or ligaments attach to bone, and inflammation of this site (enthesitis) is thought to be the cardinal lesion of PsA, w
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Yoshii, I. "AB0233 ATTAINING CDAI REMISSION IS THE FIRST GATEWAY TO ATTAIN BOOLEAN REMISSION." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1417.1–1417. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1550.

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Background:Boolean remission is most stringent but most comparable remission status for the patient with rheumatoid arthritis (RA). Clinical remission evaluated with clinical disease activity index (CDAI) is also one of the most popular index for evaluation of RA treatment. These two criteria often overlap, but some are split.Objectives:Clinical significance of attaining CDAI remission before attaining Boolean remission was investigated.Methods:Patient with RA were treated in the institute since August 2010 under treat to target (T2T) strategy. In accordance with T2T, RA patients were monitore
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Conceição, Renata Maria, Daniela Salgado Amaral, Danielle Carneiro de Menezes Sanguinetti, Amanda Cavalcanti Belo, and Valéria Moura Moreira Leite. "A satisfação de indivíduos com artrite reumatóide com o uso de tecnologia assistiva/The satisfaction individuals with reumathoid artritis and assistive technology usage." Revista Interinstitucional Brasileira de Terapia Ocupacional - REVISBRATO 4, no. 2 (2020): 144–57. http://dx.doi.org/10.47222/2526-3544.rbto25021.

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Introdução: A artrite reumatoide (AR) é uma doença autoimune e progressiva que afeta as articulações, causando problema no desempenho ocupacional. O terapeuta ocupacional intervém na conservação de energia, proteção articular e prescrição dos recursos de Tecnologia Assistiva (TA) para favorecer a funcionalidade. Compreender a satisfação com uso da TA é importante para melhorar o desenvolvimento, indicação e uso dos recursos. Objetivo: Identificar o grau de satisfação com uso da Tecnologia Assistiva por indivíduos com artrite reumatoide. Métodos: Estudo observacional, transversal, descritivo, d
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