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1

Keefe, G. P., I. R. Dohoo, J. E. Valcour, and R. L. Milton. "Ultrasonic imaging of marbling at feedlot entry as a predictor of carcass quality grade." Canadian Journal of Animal Science 84, no. 2 (2004): 165–70. http://dx.doi.org/10.4141/a03-084.

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This study evaluated the ability of ultrasonic examination at entry into the feedlot to predict carcass traits. Feeder calves (487) from eight Prince Edward Island feedlots were examined with an Aloka 500 ultrasound and Critical Vision® image analysis software to determine carcass attributes (backfat, ribeye area and intramuscular fat) at feedlot entry. These measures, along with potential confounders, were evaluated for their ability to predict carcass grade. Three statistical procedures (multinomial logistic regression, constrained multinomial logistic regression and a proportional odds logi
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2

Maciel, Isabella Cristina de Faria, Jeannine P. Schweihofer, Jenifer I. Fenton, et al. "PSXI-18 Influence of Akaushi Genetics on Beef Performance and Carcass Merit in Grain and Grass-finishing Systems." Journal of Animal Science 98, Supplement_4 (2020): 384–85. http://dx.doi.org/10.1093/jas/skaa278.676.

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Abstract The study objective was to investigate the impact of beef genetics and finishing system on beef production and carcass merit. Red Angus (RA, n = 30) and RA x Akaushi (AK, n = 30) were equally assigned to one of two finishing treatments: a mixed-species pasture forage (GRASS) or a total mixed feedlot ration (GRAIN) in three replications. Each finishing treatment had free access to mineral and water, and GRAIN were fed once daily (20% hay and 80% concentrate) over 107 d. The grazing period was 80 d. Body weight (BW) was measured after a 12-hour fasting period at the onset and end of the
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3

Takagi, Yasushi, Ken-Ichiro Kikuta, Kazuhiko Nozaki, Motoaki Fujimoto, Junya Hayashi, and Nobuo Hashimoto. "Neuronal expression of Fas-associated death domain protein and caspase-8 in the perinidal parenchyma of cerebral arteriovenous malformations." Journal of Neurosurgery 106, no. 2 (2007): 275–82. http://dx.doi.org/10.3171/jns.2007.106.2.275.

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Object The expression and localization of phosphorylated Fas-associated death domain protein (pFADD) and cleaved caspase-8 was examined in human cerebral arteriovenous malformations (AVMs). The authors focused on the perinidal parenchyma to clarify the effect of AVMs on perinidal brain tissue. Methods Seventeen cerebral AVMs were analyzed using immunohistochemical methods. Specimens were removed from patients during surgical procedures. The characteristics of the areas that stained positively for pFADD or cleaved caspase-8 were also assessed using an image analysis system. Eleven (65%) of the
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4

Field, Catherine E., Maria K. Chavez, Mohammed Abo-Ismail, and Zach D. McFarlane. "PSI-31 Retrospective analysis of growth performance and carcass ultrasound data of yearling bulls enrolled at the Cal Poly Bull Test." Journal of Animal Science 98, Supplement_4 (2020): 470–71. http://dx.doi.org/10.1093/jas/skaa278.820.

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Abstract Since 1956, the Cal Poly Bull Test has evaluated performance of yearling bulls in a multi-breed contemporary group in the western United States. The main objectives of this study were to evaluate the consistency of the relationship between growth and ultrasound traits and between the number of bulls selling and sale price over a 19-year period from 2001–2019. Out of 3,712 bulls, a total of 2,503 Angus and 453 Hereford bulls were used in the analyses using SAS. Bulls were sold in the following pre-determined breed categories; Angus Heifer Bulls, Multi-Trait Angus Bulls, Growth Angus Bu
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Umiastowska, Marta, and Marian Ciaciura. "Protected plant species of forest, lakes and peatbogs in the Western Part of the Drawskie Lakeland." Biodiversity: Research and Conservation 13, no. 1 (2009): 61–66. http://dx.doi.org/10.2478/v10119-009-0010-6.

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Protected plant species of forest, lakes and peatbogs in the Western Part of the Drawskie Lakeland A floristic study of forest communities, lakes, and peatbogs of the western part of the Drawskie Lakeland was carried out in 2006-2008. The study revealed the presence of numerous valuable plant species. More than 400 floristic lists were compiled. Plant surveys were conducted with the aid of the ATPOL square grid system. To increase the accuracy of the surveys, the basic ATPOL squares (10x10 km) were additionally subdivided into smaller ones of 1x1 km. The area of study was found to support 416
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6

Decker, Jared E., David J. Patterson, Brian Arisman, et al. "101 National Center for Applied Reproduction and Genomics (NCARG) evaluates accuracy of genomic prediction in commercial Angus cattle." Journal of Animal Science 97, Supplement_3 (2019): 84. http://dx.doi.org/10.1093/jas/skz258.173.

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Abstract One of the goals of the National Center of Applied Reproduction and Genomics (NCARG) is to demonstrate in real-world settings the potential of new technologies. To this end, we evaluated the predictive ability of the Zoetis GeneMax Advantage genomic prediction. The GeneMax Advantage test analyzes tens of thousands of single nucleotide polymorphisms (SNP) to predict the genetic potential of a commercial Angus female. Genetic predictions are provided for Calving Ease Maternal, Weaning Weight, Heifer Pregnancy, Milk, Mature Weight, Dry Matter Intake, Carcass Weight, Marbling, and Yield.
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7

He, L., H. Wu, Q. Meng, and Z. Zhou. "Growth performance, carcass traits, blood parameters, rumen enzymes, and fattening earnings of cattle fed corn silage/corn stalk silage based finishing diets." Czech Journal of Animal Science 63, No. 12 (2018): 483–91. http://dx.doi.org/10.17221/108/2018-cjas.

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This study was conducted to investigate the growth performance, carcass traits, blood parameters, rumen enzymes, and fattening earnings of beef cattle when substituting corn stalk silage with corn silage or corn grain in finishing rations. Forty-five Bohai Black steers were selected and fattened in a three-phase (4 weeks–4 weeks–16 weeks) way with one of three diets based on corn silage (CS), corn stalk silage (SS) without/with equivalent corn grain supplement (SSC), respectively. During the 24-week trial, individual feed intake and body weight were recorded every four weeks. By the end, blood
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8

Jang, Yumi, Zeinab Elsayed, Rebeka Eki, et al. "Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites." Proceedings of the National Academy of Sciences 117, no. 10 (2020): 5329–38. http://dx.doi.org/10.1073/pnas.1913280117.

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Accumulating evidence suggests participation of RNA-binding proteins with intrinsically disordered domains (IDPs) in the DNA damage response (DDR). These IDPs form liquid compartments at DNA damage sites in a poly(ADP ribose) (PAR)-dependent manner. However, it is greatly unknown how the IDPs are involved in DDR. We have shown previously that one of the IDPs RBM14 is required for the canonical nonhomologous end joining (cNHEJ). Here we show that RBM14 is recruited to DNA damage sites in a PARP- and RNA polymerase II (RNAPII)-dependent manner. Both KU and RBM14 are required for RNAPII-dependent
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9

Murdoch, WJ. "Perturbation of sheep ovarian surface epithelial cells by ovulation: evidence for roles of progesterone and poly(ADP-ribose) polymerase in the restoration of DNA integrity." Journal of Endocrinology 156, no. 3 (1998): 503–8. http://dx.doi.org/10.1677/joe.0.1560503.

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Ovarian cells within the area of impending follicular rupture in the sheep exhibit evidence of DNA fragmentation. Most cells undergo a degenerative process indicative of apoptosis and are deleted before ovulation. However, some ovarian surface epithelial cells located along the margins of ruptured follicles persist (with damaged DNA) into the ensuing luteal phase. It is conceivable that a genetically-altered progenitor cell that has survived a sub-lethal insult at ovulation (i.e. with unrepaired DNA but not committed to death) could give rise to a malignant phenotype that is propagated during
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10

Krause, Taylor, Edward Moore, Jason Duggin, Jacob Segers, and T. Dean Pringle. "PSV-36 The impact of selection using residual average daily gain and marbling EPDs on growth performance and carcass traits in angus steers." Journal of Animal Science 97, Supplement_3 (2019): 340–41. http://dx.doi.org/10.1093/jas/skz258.679.

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Abstract This study compared growth performance, feed efficiency, body composition, and carcass characteristics in Angus steers (n = 321) from bulls divergently selected for feed efficiency and marbling. Angus sires were selected based on high (10th percentile or better) and low (85th percentile or worse) residual ADG (RADG) EPD as well as high (5th percentile or better) and average (near 50th percentile) marbling (MARB) EPD. These criteria resulted in a 2x2 factorial design with four breeding lines: high RADG/high MARB, high RADG/average MARB, low RADG/high MARB, low RADG/average MARB. Data w
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11

Muir, John A., and Richard S. Hunt. "Assessing Potential Risks of White Pine Blister Rust on Western White Pine from Increased Cultivation of Currants." HortTechnology 10, no. 3 (2000): 523–27. http://dx.doi.org/10.21273/horttech.10.3.523.

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Introductions of white pine blister rust (WPBR, causal fungus: Cronartium ribicola J.C. Fischer) to eastern and western North America before 1915 caused such extensive damage that western white pine (Pinus monticola D. Don) was essentially abandoned as a manageable forest tree species for over 60 years. Recent results from WPBR resistance selection and breeding programs, and from field trials of tree spacing, pruning and bark excision treatments have supported efforts to increase establishment and to intensively manage western white pine. Western white pine is a desirable component in many for
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12

Sant’anna, Aline Cristina, Tiago Da Silva Valente, Ana Fabrícia Braga Magalhães, et al. "Relationships between temperament, meat quality, and carcass traits in Nellore cattle1." Journal of Animal Science 97, no. 12 (2019): 4721–31. http://dx.doi.org/10.1093/jas/skz324.

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Abstract The aim of this study was to evaluate the relationship between temperament in Nellore bulls with carcass and meat quality traits. In total, 1,400 bulls were studied, and temperament was assessed using two measurements: movement score (MOV) and flight speed test (FS). Both MOV and FS were measured at two time points, with background (MOVb and FSb) temperament measured at yearling age, ~550 d after birth, and the preslaughter (MOVps and FSps) temperament measured at the end of the feedlot period. The change of temperament resulting in an increase or decrease in reactivity was also used
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13

Knoche, Moritz, Eckhard Grimm, and Henrik Jürgen Schlegel. "Mature Sweet Cherries Have Low Turgor." Journal of the American Society for Horticultural Science 139, no. 1 (2014): 3–12. http://dx.doi.org/10.21273/jashs.139.1.3.

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The pressure inside a mature sweet cherry (Prunus avium L.) fruit is thought to be an important factor in rain cracking. However, to our knowledge, this pressure has never been quantified directly. The objectives of this study are to quantify: 1) the cell turgor () in fruit using a cell pressure probe (CPP) and a vapor pressure osmometer (VPO); and 2) the tissue pressure in a fruit () using both a fruit pressure probe (FPP) and a compression-plate technique (CP). The value of in mesocarp cells of mature sweet cherry fruit averaged 28.1 kPa in ‘Samba’ and 17.5 kPa in ‘Sam’ at depths below the f
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14

Arora, Avnish Kumar, and Pankaj Kumar. "Prebiotic studies on the interaction of zirconia nanoparticles and ribose nucleotides and their role in chemical evolution." International Journal of Astrobiology 20, no. 2 (2021): 142–49. http://dx.doi.org/10.1017/s1473550421000033.

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AbstractStudies on the interaction of biomolecules with inorganic compounds, mainly mineral surfaces, are of great concern in identifying their role in chemical evolution and origins of life. Metal oxides are the major constituents of earth and earth-like planets. Hence, studies on the interaction of biomolecules with these minerals are the point of concern for the study of the emergence of life on different planets. Zirconium oxide is one of the metal oxides present in earth's crust as it is a part of several types of rocks found in sandy areas such as beaches and riverbeds, e.g. pebbles of b
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15

Ben Hania, Wajdi, Anne Postec, Thomas Aüllo, et al. "Mesotoga infera sp. nov., a mesophilic member of the order Thermotogales , isolated from an underground gas storage aquifer." International Journal of Systematic and Evolutionary Microbiology 63, Pt_8 (2013): 3003–8. http://dx.doi.org/10.1099/ijs.0.047993-0.

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Strain VNs100T, a novel mesophilic, anaerobic, rod-coccoid-shaped bacterium, having a sheath-like outer structure (toga), was isolated from a water sample collected in the area of an underground gas storage aquifer. It was non-motile with cells appearing singly (2–4 µm long×1–2 µm wide), in pairs or as long chains and stained Gram-negative. Strain VNs100T was heterotrophic, able to use arabinose, cellobiose, fructose, galactose, glucose, lactose, lactate, mannose, maltose, raffinose, ribose, sucrose and xylose as energy sources only in the presence of elemental sulfur as terminal electron acce
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16

Plant, Pamela J., James R. Bain, Judy E. Correa, Minna Woo, and Jane Batt. "Absence of caspase-3 protects against denervation-induced skeletal muscle atrophy." Journal of Applied Physiology 107, no. 1 (2009): 224–34. http://dx.doi.org/10.1152/japplphysiol.90932.2008.

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The ubiquitin-proteasome system is a key proteolytic pathway activated during skeletal muscle atrophy. The proteasome, however, cannot degrade intact myofibrils or actinomyosin complexes. In rodent models of diabetes mellitus and uremia, caspase-3 is involved in actinomyosin cleavage, generating fragments that subsequently undergo ubiquitin-proteasome-mediated degradation. Here, we demonstrate that caspase-3 also mediates denervation-induced muscle atrophy. At 2 wk after tibial nerve transection, the denervated gastrocnemius of caspase-3-knockout mice weighed more and demonstrated larger fiber
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17

He, B., M. Dai, W. Huang, Q. Liu, H. Chen, and L. Xu. "Sources and accumulation of organic carbon in the Pearl River Estuary surface sediment as indicated by elemental, stable carbon isotopic, and carbohydrate compositions." Biogeosciences Discussions 7, no. 2 (2010): 2889–926. http://dx.doi.org/10.5194/bgd-7-2889-2010.

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Abstract. Organic matter in surface sediments from the upper reach of the Pearl River Estuary and Lingdingyang Bay, as well as the adjacent northern South China Sea shelf was characterized by a variety of techniques, including elemental (C and N), stable carbon isotopic (δ 13C) composition, as well as molecular-level analyses. Total organic carbon (TOC) content was 1.61±1.20% in the upper reach down to 1.00±0.22% in Lingdingyang Bay and to 0.80±0.10% on the inner shelf and 0.58±0.06% on the outer shelf. δ13C values ranged from −25.11‰ to −21.28‰ across the studied area, with a trend of enrichm
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18

Lee, Jung-Min, Ashley Cimino-Mathews, Cody J. Peer, et al. "Safety and Clinical Activity of the Programmed Death-Ligand 1 Inhibitor Durvalumab in Combination With Poly (ADP-Ribose) Polymerase Inhibitor Olaparib or Vascular Endothelial Growth Factor Receptor 1-3 Inhibitor Cediranib in Women's Cancers: A Dose-Escalation, Phase I Study." Journal of Clinical Oncology 35, no. 19 (2017): 2193–202. http://dx.doi.org/10.1200/jco.2016.72.1340.

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Purpose Data suggest that DNA damage by poly (ADP-ribose) polymerase inhibition and/or reduced vascular endothelial growth factor signaling by vascular endothelial growth factor receptor inhibition may complement antitumor activity of immune checkpoint blockade. We hypothesize the programmed death-ligand 1 (PD-L1) inhibitor, durvalumab, olaparib, or cediranib combinations are tolerable and active in recurrent women’s cancers. Patients and Methods This phase I study tested durvalumab doublets in parallel 3 + 3 dose escalations. Durvalumab was administered at 10 mg/kg every 2 weeks or 1,500 mg e
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19

Osipov, Robert M., Michael P. Robich, Jun Feng, et al. "Effect of thrombin fragment (TP508) on myocardial ischemia-reperfusion injury in hypercholesterolemic pigs." Journal of Applied Physiology 106, no. 6 (2009): 1993–2001. http://dx.doi.org/10.1152/japplphysiol.00071.2009.

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Myocardial ischemia-reperfusion (IR) injury occurs frequently in the setting of hypercholesterolemia. We investigated the potential efficacy of a novel thrombin fragment (TP508) on IR injury in a hypercholesterolemic porcine model. Twenty-one hypercholesterolemic male Yucatan pigs underwent 60 min of mid-left anterior descending coronary artery occlusion followed by 120 min of reperfusion. Pigs received either placebo (control, n = 7) or TP508 in two doses (TP508 low dose, n = 7, as bolus of 0.5 mg/kg 50 min into ischemia and an infusion of 1.25 mg·kg−1·h−1 during reperfusion period or TP508 h
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20

Hatch, Rachel, Sweta Patel, Christine Cambareri, Tanya Uritsky, and Lainie P. Martin. "Evaluation of the occurrence and management of PARP inhibitor toxicities." Journal of Clinical Oncology 38, no. 15_suppl (2020): e18073-e18073. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e18073.

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e18073 Background: Poly-adenosine diphosphate ribose polymerase inhibitors (PARPi) have become a major cornerstone of therapy in the management of patients with ovarian cancer and other cancer types. The most common adverse events with PARPi therapy include bone marrow suppression, gastrointestinal (GI) toxicity, and fatigue. Currently, information is scarce regarding the management of some of these adverse events. Methods: A retrospective, descriptive observational study of adult patients with gynecologic malignancy, who received at least 2 weeks of PARPi therapy, was conducted at the Univers
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21

Chiminazzo, Marco Antonio, Leonardo Pazzini Vieira, Diego Alves Pereira, Renon Santos Andrade, Thiago Bernardes Fernandes Jorge, and Walnir Gomes Ferreira Júnior. "EXPEDIÇÃO IFSULDEMINAS: VALORIZANDO AS CARACTERÍSTICAS SOCIOAMBIENTAIS LOCAIS NA EXTENSÃO." REVISTA BRASILEIRA DE EXTENSÃO UNIVERSITÁRIA 9, no. 1 (2018): 57. http://dx.doi.org/10.24317/2358-0399.2018v9i1.7571.

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O programa EXPEDIÇÃO IFSULDEMINAS foi criado em 2016 e é executado anualmente com o objetivo de estimular o desenvolvimento de diferentes áreas em comunidades sul-mineiras por intermédio da extensão universitária. Dentre os conjuntos temáticos que abrangem os objetivos do programa, pode-se citar a valorização da cultura do cidadão local, o cooperativismo e a gestão e educação ambiental em nível regional. Logo, relatamos nesse artigo a experiência dos autores em dois projetos contemplados pelo programa, sendo desenvolvidos nas cidades sul-mineiras de Luminárias em 2016 e Cássia em 2017. Para ta
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22

Steele, C., A. Arnold, K. Gehring, D. Griffin, and J. Savell. "Sorting Beef Subprimals by Ribeye Size at the Packer Level to Maximize Utility and Product Uniformity in Foodservice and Retail Sectors." Meat and Muscle Biology 3, no. 2 (2019). http://dx.doi.org/10.22175/mmb.10676.

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ObjectivesTo determine the impact of sorting beef carcasses at the packer level by ribeye area, instead of sorting subprimals by weight, to provide more consistent products for the end user via foodservice and retail channelsMaterials and MethodsInstrument grading technology was used to select 100 USDA Choice, yield grade 2 or 3 sides, and 100 USDA Select, yield grade 2 or 3 sides. Carcass sides were sorted into one of five ribeye area (REA) categories, as outlined in Tabsle 6.USDA Choice carcass sides were fabricated to remove beef rib, ribeye, lip-on (IMPS 112A) and beef loin, strip loin, bo
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23

Heiderscheit, Katie J., and Stephanie L. Hansen. "Effect of rumen-protected lysine on growth performance, carcass characteristics, and plasma amino acid profile in feedlot steers." Translational Animal Science 4, no. 3 (2020). http://dx.doi.org/10.1093/tas/txaa128.

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Abstract The objective of this study was to evaluate growth performance, carcass characteristics, and plasma amino acid profiles of feedlot steers fed rumen-protected Lys. Forty-two Angus-cross steers (304 ± 25 kg) were blocked by weight and fed treatment diets for 180 d (growing days 0 to 55; finishing days 56 to 180): 1) Lys-deficient diet (CON; n = 12 steers), 2) Lys-adequate diet containing soybean meal (POS; n = 12 steers), or 3) Lys-deficient diet plus supplemental rumen-protected Lys (RPL; AjiPro-L; Ajinomoto Animal Nutrition North America, Eddyville, IA; n = 18 steers). Consecutive day
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24

Hatch, Rachel V., Sweta U. Patel, Christine Cambareri, Tanya Uritsky, and Lainie P. Martin. "Evaluation of the management of PARP inhibitor toxicities in ovarian and endometrial cancer within a multi-institution health-system." Journal of Oncology Pharmacy Practice, June 17, 2021, 107815522110247. http://dx.doi.org/10.1177/10781552211024728.

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Introduction Poly-adenosine diphosphate ribose polymerase inhibitors (PARPi) have become a cornerstone of therapy in the management ovarian cancer and other cancers. PARPi are associated with significant toxicities and management strategies are primarily founded on clinical trial experience. This study aimed to provide an evaluation of patients receiving PARPi therapy within an academic health-system. Methods A retrospective, observational study of adult patients with gynecologic malignancy was conducted at the University of Pennsylvania Health System. Data was collected on patients prescribed
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25

Krause, T. R., E. R. Moore, J. Duggin, J. R. Segers, and T. D. Pringle. "The Impact of Selection using Residual Average Daily Gain and Marbling EPDs on Growth Performance and Carcass Traits in Angus Steers." Meat and Muscle Biology 3, no. 2 (2019). http://dx.doi.org/10.22175/mmb.10749.

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ObjectivesProfitability in the beef industry has narrow margins regulated by revenue from output traits like growth and carcass merit, but profitability is also largely impacted by input expenses like feed costs. Selecting for improvements in feed efficiency during the finishing phase, one of the most feed intensive segments of the industry, can help to mitigate those input costs. This study compared growth performance, feed efficiency, body composition, and carcass characteristics in Angus steers (n = 321) from bulls divergently selected for feed efficiency and marbling.Materials and MethodsA
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Mckee, R. W., D. D. Harmon, D. W. Hancock, et al. "Evaluation of Pearl Millet With and Without Soybean Hull Supplementation for Forage-Finished Beef Production Systems." Meat and Muscle Biology 3, no. 2 (2019). http://dx.doi.org/10.22175/mmb.10727.

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ObjectivesThe objective of this research was to evaluate pearl millet, a warm-season annual grass, with and without soybean hull supplementation for forage-finished beef production systems in the Southeast.Materials and MethodsEach year, 32 Angus-crossbred steers (339 ± 40 kg) were randomly assigned to one of four finishing treatments. Treatments were arranged in a 2 × 2 factorial and included two varieties of pearl millet, ‘Tifleaf 3’ (PM) and ‘Exceed’ brown mid-rib (BMR), and two levels of soybean hull supplementation, 0 and 0.75% of body weight d–1. Steers were on treatments for 90 and 84 d
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Chen, Hui, Jin Tao, Jingcheng Wang, and Lianqi Yan. "Artesunate prevents knee intraarticular adhesion via PRKR-like ER kinase (PERK) signal pathway." Journal of Orthopaedic Surgery and Research 14, no. 1 (2019). http://dx.doi.org/10.1186/s13018-019-1445-x.

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Abstract Background Intraarticular scar adhesion refers to a serious complication caused by knee surgery or trauma, leading to various sequelae (e.g., articular cartilage degeneration and knee joint stiffness). Artesunate (ART) has exhibited an effect to suppress fibroblast proliferation, whereas the exact mechanism remains unclear. This study aims to delve into the possible mechanism of ART in suppressing joint adhesion. Methods The effect of ART on reduced intraarticular adhesions was ascertained by histological staining and immunohistochemical analysis through vivo experiments. Cell Countin
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