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1

Åkerberg, Frida. "Risk Ranking Reversals and Classification Ranking Reversals in Risk Matrices." Thesis, Högskolan i Gävle, Avdelningen för datavetenskap och samhällsbyggnad, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-37112.

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The risk matrix may appear to be a simple and effective tool that is commonly used to provide an overview of risk. Previous research indicates that risk matrices contain many weaknesses which may impact the outcome of risk assessment. This thesis gives examples of strengths and weaknesses of risk matrices with focus on several types of risk ranking reversals, specifically classification ranking reversals. The constructor and the user of a risk matrix should be aware of the implications that risk ranking reversals may cause, and that these cannot be easily mitigated.
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2

Aroni, Yallercco Tony, and Cisneros Marco Daniel Mantarí. "Estimación de la seguridad vial para peatones en intersecciones aplicando la matriz de riesgo." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/652076.

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Los accidentes de tránsito es uno de los grandes peligros que afectan tanto a los individuos y a la sociedad. Cada año, más de 1.2 millones de personas mueren en el mundo y decenas de millones resultan gravemente heridas debido a los accidentes de tránsito. Actualmente, se utilizan diferentes metodologías para evaluar el nivel de seguridad vial, pero estas ya tienen parámetros determinados. Sin embargo, la matriz de riesgo permite agregar todos los atributos necesarios para una mejor evaluación. Dicha matriz se utiliza porque no requiere técnicas especializadas y es de simple aplicación. Para
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3

Christodoulou, Michalis. "Covariance matrix estimation applied in value-at-risk and margin risk methodologies." Thesis, Imperial College London, 2005. http://hdl.handle.net/10044/1/8198.

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4

Oliveira, Marcelo Knopf de. "A importância da matriz de riscos no planejamento da auditoria." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/132939.

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Com o aperfeiçoamento na forma de gestão as empresas o nível dos processos vem se ampliando cada vez mais. Uma das maneiras mais eficientes de mitigar os riscos nos processos, que se apresentam as organizações, é por intermédio uma gestão de riscos hábil, desenvolvida através da Matriz de Risco, que é o instrumento responsável por aferir os riscos bem como seus controles. A partir do referencial teórico desenvolvido na pesquisa, buscou-se confirmar a importância da Matriz de Risco para os processos de auditoria, no escopo de extinguir fraudes, erros e outros problemas enfrentados pelas organiz
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5

Pörn, Sebastian, and Arvid Rönnblom. "Assesing counterparty risk classification using transition matrices : Comparing models' predictive ability." Thesis, Umeå universitet, Institutionen för matematik och matematisk statistik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136667.

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An important part when managing credit risk is to assess the probability of default of different counterparties. Increases and decreases in such probabil- ities are central components in the assessment, and this is where transition matrices become useful. These matrices are commonly used tools when as- sessing counterparty credit risk, and contain the probability of default, as well as the probability to migrate between different predefined rating classifica- tions. These rating classifications are used to reflect the risk taken towards different counterparties. Therefore, it is important for
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6

Elom, Nwabueze. "Human health risk assessment of potentially toxic elements (PTEs) from environmental matrices." Thesis, Northumbria University, 2012. http://nrl.northumbria.ac.uk/15594/.

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In assessing human health risk of potentially toxic elements (PTEs), it is not the concentration of PTEs in the environmental matrices that is of greatest concern but the fraction that is absorbed into the body via the exposure pathways. The determination of this fraction (i.e. the bioaccessible fraction) through the application of bioaccessibility protocols is the focus of this work. The study investigated human health risk of PTEs (As, Cd, Cr, Cu, Pb, Mn, Ni and Zn) from oral ingestion of soil / dust, inhalation of urban street dust and air-borne dust (PM10). To assess health risk via oral i
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7

Alves, Alexandra Maria Meleiro. "O cálculo do Value at Risk aplicado a fundo de pensões." Master's thesis, Instituto Superior de Economia e Gestão, 2006. http://hdl.handle.net/10400.5/3601.

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Mestrado em Ciências Actuariais<br>Uma análise multi-perspectivada do risco inerente aos investimentos realizados no quadro dos Fundos de Pensões tem vindo a tornar-se cada vez mais importante, para as Sociedades Gestoras, para as Entidades Supervisoras e para as próprias empresas criadoras dos fundos, como meio imprescindível de controlo e previsão de custos e benefícios futuros. O objectivo desta dissertação é analisar uma classe de medidas de risco que tem vindo a ganhar aceitação junto dos vérios organismos, tanto devido à valiosa informação que dá, como devido à simplicidade na sua interp
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8

Staudinger, Maximilian, and Marius Günl. "Supply Risk Management of Automotive Suppliers : Development in a Fluctuating Environment." Thesis, Internationella Handelshögskolan, Högskolan i Jönköping, IHH, Centre of Logistics and Supply Chain Management, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-18420.

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Background: The implementation of procurement concepts such as JIT or singlesourcing have resulted in the emergence of new supply risks forautomotive suppliers. The economic crisis in 2008 and volatiledemand in recent years had enormous impact on the sector.Consequently, in association with lean purchasing models, newdimensions of supply risks have emerged. This creates the need forautomotive suppliers to adapt and improve their supply riskmanagement in response to the increased risk potential. There hasbeen no research on how automotive suppliers have furtherdeveloped their supply risk manage
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9

Oliveira, Lívia Maria Borges Carneiro. "Gestão de risco nas PMEs : estudo de caso na Aires Fernandes de Almeida, Lda." Master's thesis, Instituto Superior de Economia e Gestão, 2019. http://hdl.handle.net/10400.5/18586.

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Mestrado em Contabilidade, Fiscalidade e Finanças Empresariais<br>Este estudo apresenta conceitos e métodos de gestão do risco, inserido no contexto do sistema de gestão de pequenas e médias empresas (PME) portuguesas. Expõe alguns conceitos sobre risco e gestão do risco, utilizados e normalizados internacionalmente, nomeadamente pelas metodologias da International Organization for Standardization (ISO) 31000 e das metodologias do Committee of Sponsoring Oganizations of the Treadway Comission (COSO). Foi desenvolvida uma matriz de risco como forma de ampliar a visibilidade e melhor tratamento
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10

Andersson-Säll, Tim, and Johan Lindskog. "A STUDY ON THE DCC-GARCH MODEL’S FORECASTING ABILITY WITH VALUE-AT-RISK APPLICATIONS ON THE SCANDINAVIAN FOREIGN EXCHANGE MARKET." Thesis, Uppsala universitet, Statistiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-375201.

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This thesis has treated the subject of DCC-GARCH model’s forecasting ability and Value-at- Risk applications on the Scandinavian foreign exchange market. The estimated models were based on daily opening foreign exchange spot rates in the period of 2004-2013, which captured the information in the financial crisis of 2008 and Eurozone crisis in the early 2010s. The forecasts were performed on a one-day rolling window in 2014. The results show that the DCC-GARCH model accurately predicted the fluctuation in the conditional correlation, although not with the correct magnitude. Furthermore, the DCC
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Masters, Kindalin B. "Police Officer Insights into a Sex Offender Registration Scheme and Risk Assessment: Assessing the Validity of the SHARP Risk Assessment Tool." Thesis, Griffith University, 2020. http://hdl.handle.net/10072/399401.

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The sexual abuse of a child is one of the most serious crimes a person can commit and can cause a lifetime of severe and ongoing problems for the victim. With the impact of this crime being so acute and often high profile, it brings about a number of challenges in the management of these offenders in the community. The introduction of sex offender registries is the most recognised method used in managing sex offenders living in the community, and has been an established approach to management within Australia for nearly 20 years. As legislation currently stands in Australia, each state and ter
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12

Landell, Hanna. "The Risk Matrix as a tool for risk analysis : How to apply existing theories in practice in order to overcome its limitations." Thesis, Högskolan i Gävle, Avdelningen för Industriell utveckling, IT och Samhällsbyggnad, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-22025.

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Risk assessments which are part of the risk management process implies a systematic identification of risks and judgments of risk levels and are often used to create a foundation for decisions how to handle risks. Risk matrices are widely used as a tool within risk assessments. A number of articles have lately pointed out some weaknesses with the risk matrix, but also how it could be improved and how the weaknesses could be avoided. This paper describes how accepted theories have been applied in practical action in order to overcome the limitations of the risk matrix and improve the way of wor
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Santos, Tiago Alexandre Carvalho dos. "A transferência de risco em PPP." Master's thesis, Instituto Superior de Economia e Gestão, 2006. http://hdl.handle.net/10400.5/1563.

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Mestrado em Gestão e Estratégia Industrial<br>A adopção de modelos de Parcerias Público Privadas (PPP) justifica-se pelo facto de o Estado se deparar com um duplo desafio. Por um lado, a necessidade de aumentar a oferta, a qualidade e eficiência dos serviços públicos e, por outro, as reconhecidas limitações orçamentais existentes na grande maioria dos países. O presente trabalho explora o elemento fundamental e decisivo no desenvolvimento de modelos de PPP, em alternativa aos modelos de provisão tradicional de bens e serviços, nomeadamente a adequada e óptima alocação de risco entre os sectore
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14

El, Khoury Louis. "Genetic and epigenetic variation within extracellular matrix genes as risk factors for human tendinopathy." Thesis, University of Northampton, 2015. http://nectar.northampton.ac.uk/8733/.

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Background and Aims: Regular physical activities have shown to have various health benefits however there is always an accompanying risk of developing musculoskeletal soft tissue injuries. Indeed, damaged tendons account for 30-50% of sports-related injuries where the lifetime risk of Achilles tendon pathology (ATP) approaches 50% in runners, and that of patellar tendon pathology (PTP) is 21% in football players. The exact aetiology and mechanisms of tendon pathologies are still under investigation, however extrinsic and intrinsic risk factors (of which genetic) have been identified. Recent ge
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15

Luciani, A. "RISK OF BONE METASTATIZATION IN BREAST CANCER:ROLE OF MATRIX METALLOPROTEINASES AND ADAMS TISSUE EXPRESSION." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/217716.

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INTRODUCTION Breast cancer is the most common female neoplasm in developed countries: it represents the first cause of death for cancer in women between 40-55 years old. Bone metastasis are common in patients affected by advanced breast cancer. In patients affected by metastatic breast cancer (MBC), the bone represents the most common site of metastatization. Some elements can explain the high frequency of bone metastasis: the blood flow is abundant in the bone marrow, the cancer cells produce adhesion molecules than link stromal cells and bone matrix, the bone tissue is a source of growth fa
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16

Marwood, Warren. "An integrated multiprocessor for matrix algorithms /." Title page, table of contents and abstract only, 1994. http://web4.library.adelaide.edu.au/theses/09PH/09phm391.pdf.

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17

Arnold, Bruce Robert Banking &amp Finance Australian School of Business UNSW. "Ratings transitions and total return." Publisher:University of New South Wales. Banking & Finance, 2009. http://handle.unsw.edu.au/1959.4/43791.

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The expected yield to maturity on a defaultable obligation equals the nominal yield less expected default losses. However, in a mark-to-market world, one doesn't have the luxury of reporting one's performance on the basis of yield to maturity. Total return is calculated for an arbitrary holding period, and must reflect any mark-to-market gains or losses as at the close of the period-gains or losses that can be triggered by the bond's upgrade or downgrade. Thus to estimate expected total return, one must estimate not only expected default losses, but also the impact on capital price of expec
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18

Okorie, Ikechukwu Alexander. "Determination of potentially toxic elements (PTEs) and an assessment of environmental health risk from environmental matrices." Thesis, Northumbria University, 2010. http://nrl.northumbria.ac.uk/1502/.

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A former industrial site now used for recreational activities was investigated for total PTE content, uptake of the PTEs by foraged fruits and mobility of the PTEs using single extraction such as HOAc and EDTA. In order to evaluate the health risks arising from ingestion of the PTE contaminated soil, the oral bioaccessibility using in vitro physiologically based extraction test (PBET) and tolerable daily intake (TDI) or mean daily intake (MDI) was used. The PBET simulates the transition of the PTE pollutants in the soil into human gastrointestinal system while the TDI or MDI is the mass of soi
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19

Almqvist, Siri, and Oskar Nordin. "STRESS TESTING AN SME PORTFOLIO : Effects of an Adverse Macroeconomic Scenario on Credit Risk Transition Matrices." Thesis, Umeå universitet, Institutionen för matematik och matematisk statistik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-185398.

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The financial crisis of 2007-2008 was a severe global crisis causing a worldwide recession. One of the main contributing factors of the crisis was the excessive risk appetite of banks and financial institutions. Since then, regulatory authorities and financial institutions have directed focus towards risk management with the main objective to avert a similar crisis from occurring in the future. The aim of this thesis is to investigate how an adverse macroeconomic scenario would affect the migrations between risk classes of an SME portfolio, referred to as stress test. This thesis utilises two
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20

Prokofyeva, Evgeniya. "The application of diffusion gradient method (DGT) for ecological risk assessment of natural and artificial matrixes." Doctoral thesis, Università Politecnica delle Marche, 2015. http://hdl.handle.net/11566/243013.

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Il lavoro presenta le attività condotte per studiare, nell'ambito della valutazione di rischio ambientale, un metodo che descriva quantitativamente la mobilità di inquinanti organici persistenti nella fase solida del suolo e dei sedimenti. Il lavoro ha implicato la progettazione e la realizzazione di una sonda passiva in grado di campionare per diffusione le molecole organiche (Organic Diffusive Probe, ODP). La sonda ODP riproduce le condizioni necessarie per attuare la tecnica del gradiente diffusivo su strato sottile (Diffusion Gradients in Thin-film, DGT) ed è stata progettata adattando
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21

Kottzieper, Lisa. "Negative health effects related to styrene handling on factory workers." Thesis, Linnéuniversitetet, Institutionen för biologi och miljö (BOM), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-47337.

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During a risk assessment undertaken in a factory dealing with fiber reinforced plastic products in the northwestern part of Peninsular Malaysia, styrene was identified as the most potential hazard in the factory. It was therefore chosen to focus the rest of the risk assessment on this chemical. The purpose of this risk assessment was to find out which negative health effects styrene could have on the factory workers, especially on the laminators who are dealing daily with styrene at a close range during lamination through hand lay-up. This was investigated theoretically through a literature re
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Mazicioglu, Dogucan. "Adversarial Decision Making in Counterterrorism Applications." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/5028.

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Our main objective is to improve decision making in counterterrorism applications by implementing expected utility for prescriptive decision making and prospect theory for descriptive modeling. The areas that we aim to improve are behavioral modeling of adversaries with multi objectives in counterterrorism applications and incorporating risk attitudes of decision makers to risk matrices in assessing risk within an adversarial counterterrorism framework. Traditionally, counterterrorism applications have been approached on a single attribute basis. We utilize a multi-attribute prospect theory ap
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Zarinelli, Elia. "Spin-glass models and interdisciplinary applications." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00683603.

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Le sujet principal de cette thèse est la physique des verres de spin. Les verres de spin ont été introduits au début des années 70 pour décrire alliages magnétiques diluées. Ils ont désormais été considerés pour comprendre le comportement de liquides sousrefroidis. Parmis les systèmes qui peuvent être décrits par le langage des systèmes desordonnés, on trouve les problèmes d'optimisation combinatoire. Dans la première partie de cette thèse, nous considérons les modèles de verre de spin avec intéraction de Kac pour investiguer la phase de basse température des liquides sous-refroidis. Dans les
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Kang, Zhuang. "Illiquid Derivative Pricing and Equity Valuation under Interest Rate Risk." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1282168157.

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25

Odimabo, Onengiyeofori. "Risk management system to guide building construction projects in developing countries : a case study of Nigeria." Thesis, University of Wolverhampton, 2016. http://hdl.handle.net/2436/618537.

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Project risk assessment is an effective tool for planning and controlling cost, time and achieving the technical performance of a building construction project. Construction projects often face a lot of uncertainties, which places building construction projects at the risk of cost, time overruns as well as poor quality delivery. Considering the limited resources of developing countries, there is need to complete building projects on-time, on-budget, and to meet optimal quality hence, risk management is an important part of the decision making process in construction industry as it determines t
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Weston, Tanya L. "Application of a job exposure matrix to assess cancer mortality risk in a cohort of working men." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq22423.pdf.

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27

Saad, Nadia Abdel Samie Basyouni Kotb. "Random Matrix Theory with Applications in Statistics and Finance." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23698.

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This thesis investigates a technique to estimate the risk of the mean-variance (MV) portfolio optimization problem. We call this technique the Scaling technique. It provides a better estimator of the risk of the MV optimal portfolio. We obtain this result for a general estimator of the covariance matrix of the returns which includes the correlated sampling case as well as the independent sampling case and the exponentially weighted moving average case. This gave rise to the paper, [CMcS]. Our result concerning the Scaling technique relies on the moments of the inverse of compound Wishart matri
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Švecová, Pavlína. "BOZP v integrovaném systému řízení." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2008. http://www.nusl.cz/ntk/nusl-228204.

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This diploma thesis is focused on the selection of a suitable Occupational Health and Safety management system as a part of the “Integrated Management System”, and practical implementation into the business. The current occupational health and safety management system is reviewed and compared with requirements in the OHSAS technical specification. The hazard identification and evaluate risks for the chosen workplace of the business is performed and corrective action are suggested.
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AQUINO, Joás Tomaz de. "Proposta de avaliação de riscos financeiros em projetos inovadores: um estudo multicaso de empresas de tecnologia da informação do Porto Digital em Pernambuco." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/18615.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-04-24T13:24:16Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) DISSERTAÇÃO (2016-6-30) - JOÁS TOMAZ DE AQUINO.PDF.pdf: 2545956 bytes, checksum: b9aabb94688142e23c5ace4525799a04 (MD5)<br>Made available in DSpace on 2017-04-24T13:24:16Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) DISSERTAÇÃO (2016-6-30) - JOÁS TOMAZ DE AQUINO.PDF.pdf: 2545956 bytes, checksum: b9aabb94688142e23c5ace4525799a04 (MD5) Previous issue d
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Gomes, Valeria Aguiar 1982. "Efeito do anticoncepcional oral sobre as alterações de metaloproteinases da matriz extracelular em pacientes com síndrome do ovário policístico : Effect of oral contraceptives on changes of extracellular matrix metalloproteinases in patients with polycystic ovary syndrome." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310020.

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Orientador: José Eduardo Tanus dos Santos<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-11-07T16:45:40Z (GMT). No. of bitstreams: 1 Gomes_ValeriaAguiar_D.pdf: 9967733 bytes, checksum: 0f5a9488cc56b0e1272b80bd9cb6ea0b (MD5) Previous issue date: 2012<br>Resumo: A síndrome do ovário policístico (SOP) é a endocrinopatia mais comum em mulheres na idade reprodutiva e está frequentemente associada a alguns fatores de risco cardiovascular. A grande maioria das doenças cardiovasculares (DCV) ocorre inicialmente com o remodel
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Kim, Soo-Hyun. "The effects of high dimensional covariance matrix estimation on asset pricing and generalized least squares." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/34816.

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High dimensional covariance matrix estimation is considered in the context of empirical asset pricing. In order to see the effects of covariance matrix estimation on asset pricing, parameter estimation, model specification test, and misspecification problems are explored. Along with existing techniques, which is not yet tested in applications, diagonal variance matrix is simulated to evaluate the performances in these problems. We found that modified Stein type estimator outperforms all the other methods in all three cases. In addition, it turned out that heuristic method of diagonal variance
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Puzyrova, Polina. "The algorithm for constructing a decomposition matrix of innovative risks: the degree of their influence on innovation potential for integrated business structures in dynamic conditions of modern development." Thesis, Perfect Publishing, Vancouver, Canada, 2021. https://er.knutd.edu.ua/handle/123456789/19280.

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The essential composition of innovation risks that affect integrated business structures in the micro and macro environment is determined; the conditions for the emergence of innovation risk in the activities of integrated business structures are studied; the algorithm of construction of the consolidated classification matrix of innovative risks for integrated business structures is determined; the decomposition matrix of innovation risks and the degree of their impact on the innovation potential with the subsequent ranking of integrated business structures and business units in the field of p
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Kable, Bhushan M. "Identifying Structurally Significant Items Using Matrix Reanalysis Techniques." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1261417678.

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Elrgaiye, Ali Saad Ab. "Semi-quantitative Risk Assessment of an anaerobic digestion process." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016.

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Biogas is the most emerging industrial sector for energy production from renewable sources at National and European levels, and growing government funds favor the development of its market. From a process safety standpoint, Seveso Directive (Directive 2012/18/EU of the European Parliament and of the Council), but Biogas plants are complicated enough to require both their specific technology and an accurate risk assessment for design purposes. The number of accidents involving biogas plants has been too many to be ignored. Biogas plants are often operated wrongly, deficient in technological det
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Souza, Pierre Oberson de. "Otimização de portfólios de investimento : a estratégia de paridade de risco no cenário brasileiro." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/127215.

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O presente trabalho busca dar início a estudos referentes ao modelo de otimização de portfolios de investimento denominado paridade de risco no cenário brasileiro. Neste trabalho, os índices setoriais da bolsa brasileira (Bovespa) foram utilizados como ativos e com os seus dados foram estimadas carteiras com os modelos de mínima variância, de pesos iguais e de paridade de risco. Verificou-se que no modelo de paridade de risco a forma de obtenção da matriz de covariância exerce pouca influência no resultado final, que é de carteiras com distribuição de pesos e volatilidades intermediárias com r
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Parsons, William Grant. "A re-evaluation of the US EPA radon risk categorization for Unicoi County, Tennessee." [Johnson City, Tenn. : East Tennessee State University], 2003. http://etd-submit.etsu.edu/etd/theses/available/etd-0717103-133239/unrestricted/ParsonW08062003.pdf.

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Thesis (M.S.E.H.)--East Tennessee State University, 2003.<br>Title from electronic submission form. ETSU ETD database URN: etd-0717103-133239. Includes bibliographical references. Also available via Internet at the UMI web site.
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Almontashiri, Naif. "A Gain of Function Variant of the Mitochondrial Matrix Protease SPG7 Is Associated with Increased Risk of Coronary Artery Disease." Thesis, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/22665.

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Genome-wide association studies (GWAS) have identified up to 30 loci that associate with increased risk of coronary artery disease or myocardial infarction. Here, I tested the function of one locus that changed the amino acid sequence of a mitochondrial matrix protease called paraplegin (SPG7) that performs critical quality assurance functions. Loss-of-function mutations in this protease are associated with hereditary spastic paraplegia. Here, I show that this variant that changes an arginine to a glutamine at position 688 within the protease domain is a gain-of-function. Cells bearing this va
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Huťková, Miroslava. "Řízení rizik výrobní firmy v oblasti lidských zdrojů." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-232629.

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This thesis named Risk Manufacturing Companies in the Field of Human Resources reacts to increasing concern for risks nowadays. The theoretical part is dealing with general definition of risk, is giving examples of risk distinguishing and is implicating a risk factor into a company´s decision. Current theoretical knowledge of risk is connected to human resources area. Risk analysis is focusing on manufacturing process of specific company, specifically for a possible origin of risk situations caused by human factor which are employees. SWOT analysis, Ishikawa diagram, FMEA and risk matrix were
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Suchý, Ivo. "Možnosti managementu rizik zkušebních laboratoří v kontextu revidovaných norem systémů managementu." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-382730.

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The diploma thesis deals with analysis and assessment of risks in testing laboratories, where the work with risks is an unrecognized area. A part of the thesis defines risks according to standard revision 17025:2017. Subsequently, these risks are processed by selected methods, which are used for qualitative and quantitative evaluation. Risks determination in the thesis is based on methods Risk Matrix, Failure Modes & Effects Analysis (FMEA) and Bow Tie Analysis. Introducing possibilities and patterns of described methods to testing laboratories is the main aim of the thesis, this could be a wa
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Garbetti, Anna Laura. "Risk Assessment for the production of levulinic acid from second generation biomass and upgrading to γ-valerolactone". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018.

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La produzione di energia a partire da biomassa rappresenta una delle importanti alternative all’utilizzo di combustibili fossili, al fine di ridurne il consumo globale e di limitare le emissioni di gas a effetto serra. In questo contesto il processo Biofine si classifica come una delle emergenti tecnologie per la produzione di acido levulinico a partire da biomassa lignocellulosica di seconda generazione. L’acido levulinico può essere successivamente idrogenato a γ-valerolactone, a sua volta alla base di processi di produzione di biocombustibili. Tuttavia, recenti studi hanno rivelato un aume
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Gabriš, Ondrej. "Software Projects Risk Management Support Tool." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2011. http://www.nusl.cz/ntk/nusl-412827.

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Management projektů a jejich rizik je v současnosti rozvíjející se disciplína, která si získává stále větší pozornost a uplatnění v praxi. Tato práce popisuje úvod do problematiky řízení rizik, zkoumání metod jejich identifikace, vyhodnocení a managementu, předcházení jejich následkům a jejich zvládání. V další části práce byla provedena analýza vzorků rizik z reálných projektů, byly popsány metody pro identifikaci a vyhodnocení následků rizik v úvodních fázích softwarového projektu, taktéž byly popsány atributy rizik a navržen způsob jejich dokumentace. V závěrečné části zadání byl navržen a
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Отич, Т. "Механізм визначення ефективної ставки резервування за кредитними операціями у період кризових явищ в економіці". Thesis, Національний університет ДПС України, 2011. http://essuir.sumdu.edu.ua/handle/123456789/62456.

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В роботі розглядаються механізм формування резервів за кредитними операціями на основі перехідних матриць ймовірностей.<br>The paper considers the mechanism of formation of reserves for credit operations on the basis of transition probabilities matrices.
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Brito, Ana Alexandra Subtil de. "Implementação do modelo de Credit Var aplicado a uma carteira de crédito." Master's thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/5727.

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Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Matemática e Aplicações - Actuariado, Estatística e Investigação Operacional<br>As perdas de crédito não são unicamente consequência de eventos de incumprimento (default)da contraparte, as migrações nas categorias de rating dos emitentes também originam perdas. Dadas as características particulares dos instrumentos de crédito, como as obrigações, surge a necessidade de uma medida de risco apropriada para uma carteira de dívida. A presente dissertação tem como object
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44

Ochuko, Rita E. "E-banking operational risk assessment. A soft computing approach in the context of the Nigerian banking industry." Thesis, University of Bradford, 2012. http://hdl.handle.net/10454/5733.

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This study investigates E-banking Operational Risk Assessment (ORA) to enable the development of a new ORA framework and methodology. The general view is that E-banking systems have modified some of the traditional banking risks, particularly Operational Risk (OR) as suggested by the Basel Committee on Banking Supervision in 2003. In addition, recent E-banking financial losses together with risk management principles and standards raise the need for an effective ORA methodology and framework in the context of E-banking. Moreover, evaluation tools and / or methods for ORA are highly subjective,
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45

Lacki, Jan. "From Matrices to Hilbert Spaces: The Interplay of Physics and Mathematics in the Rise of Quantum Mechanics." Wissenschaftlicher Verlag Harri Deutsch, 2011. https://slub.qucosa.de/id/qucosa%3A16259.

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O’Mara, Tracy Ann-Maria. "The association of single nucleotide polymorphisms with endometrial cancer risk and prognosis." Thesis, Queensland University of Technology, 2013. https://eprints.qut.edu.au/63648/1/Tracy_O%E2%80%99Mara_Thesis.pdf.

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Endometrial cancer is one of the most common female diseases in developed nations and is the most commonly diagnosed gynaecological cancer in Australia. The disease is commonly classified by histology: endometrioid or non-endometrioid endometrial cancer. While non-endometrioid endometrial cancers are accepted to be high-grade, aggressive cancers, endometrioid cancers (comprising 80% of all endometrial cancers diagnosed) generally carry a favourable patient prognosis. However, endometrioid endometrial cancer patients endure significant morbidity due to surgery and radiotherapy used for disea
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Kormi, I. (Immi). "Translational perspectives on matrix metalloproteinase 8 and other inflammatory biomarkers in cardiovascular diseases." Doctoral thesis, Oulun yliopisto, 2017. http://urn.fi/urn:isbn:9789526215297.

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Abstract Cardiovascular diseases (CVD), and especially atherosclerotic vascular diseases (ASVD), are the largest cause of morbidity and premature death worldwide. Coronary heart disease (CHD) and cerebrovascular disease (stroke) are common and severe manifestations of ASVD. Atherosclerosis is a chronic inflammatory disease and lipoprotein metabolism disorder. If the regulation of inflammatory process is disturbed, the systemic release of pro-inflammatory mediators, including matrix metalloproteinases (MMPs), may lead to a low-grade systemic inflammation, which is a risk factor for CVDs. MMPs a
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48

Ochuko, Rita Erhovwo. "E-banking operational risk assessment : a soft computing approach in the context of the Nigerian banking industry." Thesis, University of Bradford, 2012. http://hdl.handle.net/10454/5733.

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This study investigates E-banking Operational Risk Assessment (ORA) to enable the development of a new ORA framework and methodology. The general view is that E-banking systems have modified some of the traditional banking risks, particularly Operational Risk (OR) as suggested by the Basel Committee on Banking Supervision in 2003. In addition, recent E-banking financial losses together with risk management principles and standards raise the need for an effective ORA methodology and framework in the context of E-banking. Moreover, evaluation tools and / or methods for ORA are highly subjective,
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Ngabirano, Laure. "Matrices Emplois-Expositions : Exemples de création, validation et application." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS072.

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En épidémiologie des risques professionnels, l’évaluation de l’exposition est communément basée sur les réponses à un questionnaire, notamment pour explorer l’exposition à des facteurs, comme les facteurs psychosociaux et les facteurs biomécaniques en milieu professionnel. Ce mode d’évaluation peut être entaché de biais : biais de classement (notamment de mémorisation), biais sur les estimations des associations observées avec des variables de santé (notamment lorsque l’exposition est recueillie en même temps que la maladie). Les matrices emplois-expositions (MEE) sont une méthode alternative
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Martin, Jennifer M. "Quantification of the matrix hydraulic conductivity in the Santa Fe River Sink/Rise system with implications for the exchange of water between the matrix and conduits." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0002882.

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