Journal articles: 'RLCCr'

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Pelisson, Camila Fernandes, Silvia Manduca Trapp, and Bernardo Kemper. "Estudo comparativo in vitro do movimento de gaveta em joelhos de caninos submetidos a duas técnicas extracapsulares de correção da instabilidade após ruptura do ligamento cruzado cranial." Ciência Rural 40, no. 6 (July 9, 2010): 1335–40. http://dx.doi.org/10.1590/s0103-84782010005000097.

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A ruptura do ligamento cruzado cranial (RLCCr) é uma desordem ortopédica comum em cães que promove a instabilidade da articulação do joelho, resultando em claudicação e alterações degenerativas progressivas desta. A melhor técnica para reparação da RLCCr ainda não está bem elucidada. A maioria das técnicas alcança uma taxa de sucesso entre 80 a 90% e todas apresentam vantagens e desvantagens. O objetivo deste trabalho foi avaliar os resultados da estabilização extracapsular utilizando dois pontos distintos de ancoragem na articulação femoro-tibio-patelar como forma de tratamento da RLCCr em cães. Para tanto, foram utilizados 20 membros pélvicos de caninos. Após a RLCCr, todos os membros receberam avaliação da eficiência da técnica por meio do estudo da estabilidade crânio-caudal do joelho em flexão de 90° e extensão de 135°. As estabilizações extracapsulares realizadas nos cadáveres conferiram estabilidade crânio-caudal sem demonstrar superioridade de uma ou outra técnica, e nenhuma delas pode atribuir estabilidade isométrica quando testadas com os membros em 90° e 130°.

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Silva, R. F., J. U. Carmona, and C. M. F. Rezende. "Uso de plasma rico em plaquetas intra-articulares como tratamento pós-cirúrgico da ruptura do ligamento cruzado cranial num cão." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 64, no. 4 (August 2012): 847–52. http://dx.doi.org/10.1590/s0102-09352012000400009.

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Relata-se o caso de um cão que recebeu injeções intra-articulares de plasma rico em plaquetas (PRP) durante o pós-operatório do tratamento cirúrgico de ruptura do ligamento cruzado cranial (RLCCr). Os resultados clínicos e da avaliação da marcha mediante plataforma de força neste paciente sugerem a utilização de injeções intra-articulares de PRP como terapia pós-cirúrgica no tratamento da RLCCr.

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Dal-Bó, Ísis dos Santos, Cássio Ricardo Auada Ferrigno, Daniela Fabiana Izquierdo Caquías, Marcos Ishimoto Della Nina, Márcio Poletto Ferreira, Adriana Valente de Figueiredo, Renato Albuquerque de Oliveira Cavalcanti, Jaqueline França do Santos, and Vanessa Couto de Magalhães Ferraz. "Correlação entre ruptura de ligamento cruzado cranial e lesão de meniscomedial em cães." Ciência Rural 44, no. 8 (2014): 1426–30. http://dx.doi.org/10.1590/0103-8478cr20130670.

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O presente trabalho correlacionou o tempo de ruptura do ligamento cruzado cranial (RLCCr) à lesão em menisco medial e ao tipo de lesão observada em cães tratados por estabilização dinâmica (osteotomias) ou estática (sutura fabelo-tibial). Este estudo retrospectivo avaliou os registros de 104 cães (117 joelhos). As osteotomias foram realizadas em 98 articulações, a sutura fabelo-tibial em 15 joelhos e, em 4 joelhos, foi realizada apenas artrotomia exploratória. A média de idade foi 4,5 anos, 41% dos cães eram machos e 59%, fêmeas e a média da massa corporal foi 32,7kg. Os tipos de lesão do menisco medial observados foram: tipo 1, 2, 3, 4, 6, 7 e associações dos tipos 1-4, 1-6 e 1-7. O tipo 1 foi o mais prevalente, sendo responsável por 32,5% dos casos. Não foram encontradas correlações entre a presença ou não de lesão de menisco medial e o tempo de ocorrência da RLCCr e entre o tipo de lesão de menisco medial e o tempo de RLCCr.

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Salme, Deryck Picioneri, CARLOS EVERTON CURTI, MURILO CEZAR CURTI, EGON JOSÉ FUCK, ELIANE THOMACELLI FUCK, ANA PAULA SALAMÃO, GABRIELA NASCIMENTO, and SÉRGIO PINTER GARCIA FILHO. "OSTEOTOMIA DE NIVELAMENTO DO PLATÔ TIBIAL PARA O TRATAMENTO DA RUPTURA BILATERAL DO LIGAMENTO CRUZADO CRANIAL EM CÃO: RELATO DE CASO." Revista de Ciência Veterinária e Saúde Pública 5, no. 2 (August 31, 2018): 184. http://dx.doi.org/10.4025/revcivet.v5i2.41794.

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A Ruptura do ligamento cruzado cranial (RLCCr) é uma das enfermidades articulares mais comuns no cão e diversas são as técnicas cirúrgicas utilizadas para correção de sua instabilidade, porém nenhuma delas impede o desenvolvimento da doença articular degenerativa (DAD). Entretanto deve-se promover a estabilidade articular, garantindo qualidade de vida ao animal. A osteotomia de nivelamento do platô tibial (TPLO) é umas das técnicas mais utilizadas na atualidade e tem demonstrado melhores resultados quanto ao retorno funcional nos animais submetidos a este procedimento. O objetivo deste trabalho é avaliar o resultado da técnica de osteotomia de nivelamento do platô da tíbia (TPLO) em um cão com RLCCr bilateral.

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Santos, Jaqueline França dos, Cássio Ricardo Auada Ferrigno, Márcio Poletto Ferreira, Olicies da Cunha, Kelly Cristiane Ito, Vanessa Couto de Magalhães Ferraz, Daniela Fabiana Izquierdo Caquias, Marcos Ishimoto Della Nina, Adriana Valente Figueiredo, and Alexandre Navarro Alves de Souza. "Fratura proximal de tíbia após cirurgia extracapsular para correção de ruptura de ligamento cruzado cranial em cão." Ciência Rural 43, no. 3 (February 1, 2013): 462–65. http://dx.doi.org/10.1590/s0103-84782013005000001.

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Ruptura de ligamento cruzado cranial (RLCCr) é a afecção ortopédica mais frequente no joelho de cães e a sutura fabelo-tibial é frequentemente utilizada na sua correção. Essa técnica pode estar associada com complicações incisionais, lesão tardia de menisco, edema associado ao material de sutura e infecção. O objetivo desta nota foi relatar a ocorrência de fratura proximal de tíbia em um cão, causada por complicação em sutura fabelo-tibial para correção de RLCCr. Um canino atendido em outro serviço foi submetido à osteossíntese com placa 2,0mm para correção de complicação em técnica extra-capsular, na qual houve fratura da tíbia na região do orifício criado para confecção da sutura fabelo-tibial. Houve falha dos implantes e a placa foi removida. A fratura foi estabilizada com fixador esquelético externo circular, sendo constatada, após 120 dias, consolidação.

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Buquera, L. E. C., J. G. Padilha Filho, J. C. Canola, I. C. Talieri, and J. M. Furlani. "Estabilização extra-articular do joelho com fáscia lata autógena em cães de raças de grande porte." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 59, no. 3 (June 2007): 685–94. http://dx.doi.org/10.1590/s0102-09352007000300021.

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Avaliou-se a sutura fabelar lateral (SFL) com fáscia lata autógena para estabilização dos joelhos de cães de raças de grande porte, acometidos por ruptura do ligamento cruzado cranial (RLCCr). Os animais foram submetidos à avaliação clínica e radiográfica no pré-operatório e aos 60, 180 e, em alguns casos, 360 dias de pós-operatório. A partir do 60º dia, os cães apresentavam-se apoiando o membro normalmente ou com claudicação com apoio contínuo do membro. No 360º dia, quatro joelhos apresentavam-se estáveis, e o restante demonstrava instabilidade leve. No 360º dia, dos seis membros avaliados, três não haviam recuperado a medida da coxa aferida no pré-operatório. Os escores de doença articular degenerativa (DAD) para os períodos de 180 e 360 dias foram significativamente maiores que os atribuídos no pré-operatório. A SFL com fáscia lata foi adequada para o tratamento de RLCCr em cães de raças de grande porte, quando consideradas a estabilidade do joelho e a deambulação, e não impediu ou retardou a evolução da DAD.

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Laine, Christiane, Tarja Tamminen, and Bo Hortling. "Carbohydrate structures in residual lignin-carbohydrate complexes of spruce and pine pulp." Holzforschung 58, no. 6 (October 1, 2004): 611–21. http://dx.doi.org/10.1515/hf.2004.115.

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Abstract Residual lignin carbohydrate complexes (RLCC) were isolated enzymatically from spruce and pine pulp. The RLCCs contained 4.9–9.4% carbohydrates, with an enrichment of galactose and arabinose compared to the original pulp samples. The main carbohydrate units present in all studied RLCCs were 4-substituted xylose, 4-, 3- and 3,6-substituted galactose, 4-substituted glucose and 4 and 4,6-substituted mannose. These units were assigned to carbohydrate residues of xylan, 1,4- and 1,3/6-linked galactan, cellulose and glucomannan. RLCCs of surface material and the inner part of spruce kraft pulp fiber were compared to obtain information on the heterogeneity of layers of the fiber wall. The 1,4-linked galactan was the major galactan in RLCC of fiber surface material of spruce kraft pulp. Towards the inner part of the fiber, the proportion of 1,3/6-linked galactan increased relative to 1,4-linked galactan. This finding is presented for the first time. 1,3/6-Linked galactan structures are suggested to have a role in restricting lignin removal from the secondary fiber wall. RLCCs of three different alkaline pine pulps were studied before and after oxygen delignification to evaluate differences resulting from the cooking method. The pulps were conventional kraft pine pulp (PCK), a polysulfide/anthraquinone pine pulp (PPSAQ) and a soda/anthraquinone pine pulp (PSoAQ); all were cooked to approximately kappa number 30. Small differences were found in the carbohydrate structures of the unbleached pulps. The study indicated that the RLCC of unbleached PSoAQ pulp contained longer oligomeric carbohydrate chains and less branched 1,3/6-linked galactan residues than the RLCCs of unbleached PCK and PPSAQ pulps. The RLCC of the unbleached PSoAQ also contained more 1,4-linked glucose units suggesting a greater number of linkages of lignin to cellulose in the PSoAQ pulp than in the other two pulps. All RLCCs of oxygen-delignified pulps had more non-reducing ends and less 1,3/6-linked galactan than the corresponding RLCCs of the unbleached pulps. The RLCC of the oxygen-delignified PSoAQ pulp had a higher ratio of 1,4-galactan to 1,3/6-linked galactan and shorter xylan residues than the RLCCs of oxygen-delignified PCK and PPSAQ pulps.

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Kemper, Bernardo, Silvia Manduca Trapp, Tássio Falleiros Porto, and Flavio Antonio Barca. "Movimento de gaveta em joelhos de cães submetidos à estabilização extracapsular após secção do ligamento cruzado cranial in vitro." Ciência Rural 43, no. 6 (May 10, 2013): 1096–101. http://dx.doi.org/10.1590/s0103-84782013005000063.

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A técnica TightRope, que procura aperfeiçoar a estabilização extra-capsular com sutura lateral, por meio da realização de mínimas incisões e criação de túneis ósseos em pontos isométricos, que permitem a inserção de mecanismo que anula o movimento de gaveta, além de reduzir a ocorrência de complicações graves. Dessa forma, objetivou-se avaliar a modificação da técnica TightRope em joelhos de cadáveres caninos com a finalidade de disponibilizar um procedimento simples e de custo reduzido para tratamento da Ruptura do ligamento cruzado cranial (RLCCr). Experimentalmente, foram utilizados 20 membros pélvicos de dez cadáveres caninos, provenientes do setor de patologia da Universidade Norte do Paraná, os quais pesavam entre 6,3 e 24kg. Para estabilização do LCCr, rompido intencionalmente, foi adotada a técnica de TightRope modificada utilizando fio de poliamida, cavilha e emprego de um parafuso ortopédico para proporcionar a fixação óssea. Comparando os valores de deslocamento obtidos durante a realização do movimento de gaveta previamente à ruptura do LCCr e após a realização do procedimento cirúrgico, observou-se que a modificação da técnica TightRope promoveu estabilidade significativa para a maioria (12 de 20) dos joelhos testados (P=0,0033). Contudo, essa estabilidade foi inferior, quando comparada à estabilidade do ligamento intacto.

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Garcia, Érika Fernanda Villamayor, João Eduardo Wallau Schossler, and Maicon Pinheiro. "Ruptura do ligamento cruzado cranial em um gato: reconstituição com fáscia lata." Ciência Rural 42, no. 8 (August 2012): 1446–49. http://dx.doi.org/10.1590/s0103-84782012000800019.

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Em gatos, a ruptura do ligamento cruzado cranial (RLCC) trata-se de diagnóstico raro e a correção cirúrgica propicia o retorno mais rápido à função do membro. Foi atendida, no Hospital Veterinário da Universidade Federal de Santa Maria (UFSM), uma gata apresentando claudicação aguda e dor à palpação do joelho direito. O diagnóstico de RLCC foi realizado através dos testes de compressão tibial e gaveta cranial positivos e confirmado na cirurgia. Optou-se por realizar a reconstituição do ligamento com fáscia lata e, após achados clínicos pós-operatórios e em longo prazo concluiu-se que a técnica apresentou resultados satisfatórios neste caso.

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Hermans-Lokkerbol, A., and R. Verpoorte. "Purification of Secologanin fromLonicera tataricaExtracts Using RLCC." Planta Medica 53, no. 06 (December 1987): 546–48. http://dx.doi.org/10.1055/s-2006-962808.

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San-Um, Wimol, Bandhit Suksiri, and Patinya Ketthong. "A Simple RLCC-Diode-Opamp Chaotic Oscillator." International Journal of Bifurcation and Chaos 24, no. 12 (December 2014): 1450155. http://dx.doi.org/10.1142/s0218127414501557.

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This paper presents a simple autonomous chaotic oscillator. The design method is primarily based on a linear oscillator constructed by a closed loop connection of two building blocks, i.e. an inverting active integrator and a passive second-order LC integrator. A diode is inserted in parallel to the two building blocks for inducing chaos. The mathematical model reveals a set of three-dimensional ordinary differential equations, containing seven terms with four constants and an exponential nonlinearity. The dynamics properties are investigated in terms of an equilibrium point, Jacobian matrix, chaotic attractors, bifurcation, Lyapunov exponents, and chaotic waveforms in time domain. The proposed chaotic oscillator potentially exhibits complex dynamical behaviors through the utilization of only six minimal electronic components.

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Tatarunas, Angélica Cecília, Julia Maria Matera, Renata Moris Domenico Oliveira, Renata Ferri Macchione, and Milena Brugnaro. "Estudo retrospectivo do tratamento da ruptura de ligamento cruzado cranial no cão por técnica cirúrgica extra-articular." Brazilian Journal of Veterinary Research and Animal Science 44, no. 3 (June 1, 2007): 200. http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2007.26639.

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As técnicas extra-capsulares têm sido amplamente utilizadas para a reparação da ruptura do ligamento cruzado cranial no cão (RLCC); e, a sutura fabelo tibial tem se tornado uma das mais populares. A presente pesquisa teve por finalidade avaliar a evolução clínica de pelo menos 4 meses de pós-operatório de 19 cães (20 articulações) portadores de RLCC e submetidos a técnica acima descrita. Realizou-se entrevista com o proprietário e exame clínico consistindo de avaliação do escore de claudicação, teste de gaveta e mensuração do diâmetro da coxa, volume e ângulo da articulação do joelho. De acordo com os proprietários 90% dos animais apresentaram recuperação boa ou ótima após o tratamento cirúrgico, variando de ausência de claudicação com claudicação esporádica. A avaliação clínica denotou resultado favorável no que tange ao teste de gaveta e escore de claudicação. As mensurações objetivas, contudo, não corroboraram na mesma proporção com os resultados clínicos.

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Zhu, Xiao, Guo Liang Tao, Peng Fei Qian, De Yuan Meng, and He Zuo. "The Simulation Study of a New-Type Frictionless Pneumatic Cylinder." Applied Mechanics and Materials 278-280 (January 2013): 337–40. http://dx.doi.org/10.4028/www.scientific.net/amm.278-280.337.

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A new-type frictionless pneumatic cylinder with an aerostatic bearing as its piston can decrease the friction significantly. The stability and the leakage of this cylinder mostly depend on the radial load carrying capacity(RLCC) and the air consuming of the bearing. In order to make a better use of this cylinder in pneumatic servo systems, a simulation study on the influence of the structural parameters and time-varying surrounding parameters to this cylinder was carried out on the basis of a numerical solution method based on finite element method(FEM) which was constructed to solve Reynolds equations in this paper. Simulation shows that introducing a recess chamber at the end of the orifice hole can increase the RLCC significantly and smooth the sharp distribution of the pressure around the orifices in the air film, which makes the bearing working more stable; the time-varying parameters have a combined effects on the performance characteristics of the bearing.

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Minli, Zhang, Michael J. Stout, and Isao Kubo. "Isolation of ecdysteroids fromVitex strickeri using RLCC and recycling HPLC." Phytochemistry 31, no. 1 (January 1992): 247–50. http://dx.doi.org/10.1016/0031-9422(91)83046-n.

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Baraúna Júnior, Durval, Cláudio Roehsig, Leandro Branco Rocha, Ricardo Chioratto, and Eduardo Alberto Tudury. "Técnica de interligação extracapsular fêmoro-fabelo-tibial na ruptura do ligamento cruzado cranial em cães: achados clínicos e radiográficos." Ciência Rural 37, no. 3 (June 2007): 769–76. http://dx.doi.org/10.1590/s0103-84782007000300026.

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O objetivo deste trabalho foi avaliar os resultados da técnica de interligação extracapsular fêmoro-fabelo-tibial, como forma de tratamento da ruptura do ligamento cruzado cranial (RLCC) espontânea em cães, utilizando para isto avaliações clínicas e radiográficas. Neste estudo, foram operados 13 cães, divididos em dois grupos: ruptura unilateral (RU) e ruptura bilateral (RB). O peso variou entre 2,3 e 53kg (mediana 6,7kg) e o intervalo entre a suspeita da lesão observada pelos proprietários e os procedimentos cirúrgicos variaram entre três e 365 dias (média de 123 dias). Em nenhum dos 13 joelhos operados foram observadas complicações transoperatórias. Após 30 dias de pós-operatório, os dois grupos apresentaram diferença estatisticamente significante (P=0,05) nos parâmetros funcionais avaliados, com exceção da dor e disposição para levantar o membro contralateral no grupo de cães com ruptura bilateral. Ao exame radiográfico nos dias zero e 180, a evolução das alterações degenerativas foi observada em 84,6% dos casos. A técnica de interligação extracapsular fêmoro-fabelo-tibial é eficiente na estabilização imediata da articulação com RLCC, oferecendo recuperação funcional ao reduzir o deslocamento cranial e a rotação interna da tíbia, porém não impede a progressão da osteoartrite.

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Agjee, Na’eem Hoosen, Onisimo Mutanga, Michael Gebreselasie, and Riyad Ismail. "A Comparison of Regression Tree Approaches to Modelling the Efficacy of Water Hyacinth Biocontrol Using Multitemporal Spectral Datasets." Journal of Spectroscopy 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/7960314.

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Water hyacinth (Eichhornia crassipes) is an exotic plant species that is effectively controlled byNeochetinaspp. weevils. This study is aimed at determining if spectroscopic data may be utilized to predict insect-induced stress on water hyacinth plants. Single target regression trees (STRTs), multitarget regression trees (MTRTs), and random forest multitarget regression trees (RF-MTRTs) have been used to predict feeding scar damage (FSD) and relative leaf chlorophyll content (RLCC) from hyperspectral canopy reflectance data. Results from this study show that the correlation coefficient of STRTs (training accuracy: 76%–97%; validation accuracy: 47%–86%) performs better than MTRTs (training accuracy: 74%–90%; validation accuracy: 45%–77%) for all infestation levels but are difficult to interpret simultaneously. In contrast, MTRTs (size: 23–35 nodes) are much smaller and more interpretable than STRTs (size: 11–47 nodes) because they predict FSD and RLCC simultaneously. Importantly, RF-MTRTs (training accuracy: 95%–98%; validation accuracy: 55%–88%) yield better predictive performance than STRTs and MTRTs for all infestation levels. It is concluded that MTRTs can be utilized for model interpretation as they are more interpretable; however, RF-MTRTs offer an improved predictive performance.

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Park, Keeyoung, Hyungkee Choi, Chulhee Lee, and Soomi Hong. "A Study on Partial Discharge Diagnostic System for Power Cable using RLCR." KEPCO Journal on Electric Power and Energy 2, no. 1 (March 30, 2016): 43–47. http://dx.doi.org/10.18770/kepco.2016.02.01.043.

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Matera, Julia Maria, Angélica Cecília Tatarunas, Renata Moris Domenico Oliveira, Milena Brugnaro, and Renata Ferri Macchione. "Estudo epidemiológico retrospectivo de cães portadores de ruptura do ligamento cruzado cranial: 323 casos (1999 a 2005)." Brazilian Journal of Veterinary Research and Animal Science 44, supl. (December 3, 2007): 88. http://dx.doi.org/10.11606/issn.1678-4456.bjvras.2007.26595.

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O objetivo do presente trabalho foi caracterizar a população de cães portadores de ruptura do ligamento cruzado cranial (RLCC) para fatores considerados de risco como raça, idade, sexo e peso corporal. A base de dados consistiu de informações resgatadas de prontuários de 323 cães com diagnóstico de ruptura de ligamento cruzado cranial atendidos no Serviço de Cirurgia de Pequenos Animais do Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo em um período de 7 anos (1999 a 2005). Os resultados mostraram que as raças de maior prevalência foram o Leonberger (100%), Cane Corso (66,7%), Dogue de Bordeau (50%), Starffordshire Terrier (40%) e o Chow Chow (36%), estando ainda o Rottweiler (11,6%) e o Labrador Retriever (8,1%) em 10º e 13º lugares, respectivamente. As idades de maior freqüência foram 2, 4, 3, 7 e 6 anos (média = 5,58 anos). Fêmeas (59,14%) foram mais acometidas do que machos (40,86%) e animais inteiros (76,15%) foram mais representativos do que animais castrados (17,76%). Quanto ao peso, entre 6 e 15 kg (32,82%) seguido por animais entre 36 e 45 kg (17,03%). Pode-se observar que os dados em nosso meio tendem a se assemelhar com a literatura estrangeira: ocorrência da RLCC em animais mais jovens de raças de grande porte e gigantes, o Rottweiler como uma raça em comum a fêmea é mais representativa do que o macho.

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Ianos, Maria Adelina, Ester Caballé, Cristina Petreñas, and Ángel Huguet. "Language attitudes of young Romanians in Catalonia (Spain): The role of heritage language maintenance programs." Multilingua 38, no. 3 (May 27, 2019): 335–55. http://dx.doi.org/10.1515/multi-2018-0069.

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Abstract This article presents a mixed method analysis of the language attitudes held by secondary education students of Romanian origin, which are members of the second largest immigrant population living currently in Catalonia. The relevance of this data is based on the cardinal role played by attitudes in the success of any educational or linguistic policy (Lewis, E. Glyn. 1981. Bilingualism and bilingual education. Oxford, UK: Pergamon.) – a topic of special relevance in contexts with considerable migratory influxes, such as Catalonia, which aims to achieve social cohesiveness in a framework of interculturalism and multilingualism. The various initiatives implemented for this purpose include the heritage language maintenance programs, such as the “Romanian Language, Culture, and Civilization” (RLCC) program. The results showed that the young Romanians had the most favourable attitudes towards Spanish, followed closely by Romanian, and lastly Catalan, which was the least valued language. Furthermore, these attitudinal patterns were not determined by RLCC attendance. The insights provided by the in-depth interviews indicated various components and meanings associated with the attitudes towards the three languages. Namely, attitudes towards Spanish were primed by its international status and ease of learning, while attitudes towards Catalan were build on its integrative value and social status. Although esteemed for its emotional and symbolic bonds, Romanian seemed to be on a path towards invisibilization. Finally, the educational and social implications of these findings are discussed, emphasising the importance of involving and working with both the autochthonous and the Romanian immigrant population.

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Jung, Eui-bung, Chul-hee Lee, Soo-mi Hong, Hyung-kee Choi, and Kee-young Park. "A Study on the Electric Fire Safety System Technology for Livestock House using RLCR Algorithm." International Journal of Advanced Science and Technology 113 (April 30, 2018): 71–82. http://dx.doi.org/10.14257/ijast.2018.113.08.

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Palmieri, Raffaele, Alfonso Piciocchi, Valentina Arena, Luca Maurillo, Maria Ilaria Del Principe, Giovangiacinto Paterno, Tiziana Ottone, et al. "Clinical Relevance of- Limit of Detection (LOD) - Limit of Quantification (LOQ) - Based Flow Cytometry Approach for Measurable Residual Disease (MRD) Assessment in Acute Myeloid Leukemia (AML)." Blood 136, Supplement 1 (November 5, 2020): 37–38. http://dx.doi.org/10.1182/blood-2020-139557.

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Background: In Acute Myeloid Leukemia (AML), identification of measurable residual disease (MRD) thresholds with clinical significance is still a matter of debate. For this purpose, multiparametric flow cytometry (MFC) is extensively employed for MRD quantification, due to high sensitivity (down to 1:10-3/10-5 cells) and wide applicability (up to 90% of cases). The identification of 20 clustered residual leukemic cells seems sufficient for the recognition of MRD presence (lower limit of detection [LOD]), whereas a cluster of 50 events may be the minimum threshold for the quantification of a cell population (lower limit of quantitation [LOQ]), provided a sufficient denominator of relevant events (500'000-1'000'000) is acquired. Methods: Using a MFC assay, we assessed the predictive power of a threshold calculated applying the criteria of LOD and LOQ on 261 intensively treated AML patients enrolled in the GIMEMA AML1310 prospective trial.According to the protocol design, patients with a bone marrow residual leukemic cells count (RLCc) equal or above 0.035% of the total no. of mononuclear (MNC) cells qualified as MRDpos,, whileusing LOD and LOQ, we selected the following categories of patients: 1) LODneg if RLCc was below LOD (20x100/total no. of events); 2) LODpos-LOQneg if RLCc was between LOD and LOQ; and 3) LOQpos if RLCc was above LOQ (50x100/total no. of events). Results: The ELN target of 500'000 events was reached in 182/261 (69.6%) patients. Overall, using the predefined AML1310 protocol MRD threshold, 154 (59%) and 107 (41%) were MRDneg and MRDpos, respectively, whereas 74 (28.4%), 43 (16.5%) and 144 (54.4%) patients were classified as LODneg, LODpos-LOQneg and LOQpos, respectively. Two-year overall survival (OS) was 75.4% vs. 79.8% vs. 66.4% for LODneg, LODpos-LOQneg and LODpos, respectively (p=0.1197), and 74.5% vs. 66.4% according to AML1310 protocol 0.035% threshold for MRDneg and MRDpos patients, respectively (p=0.3521). Due to superimposable outcome, LOD-LOQneg and LODpos-LOQneg categories were combined. Accordingly, LODneg/LODpos-LOQneg and LOQpos groups clearly differed in terms of OS (77% vs. 66.4%, p=0.0437) [FIGURE 1A]. Such a figure was challenged in multivariate analysis (p=0.048, HR 0.628, 95% CI 0.396-0.997) that confirmed the independent role of LOD-LOQ approach in influencing OS. To enhance the predictivity of LOD-LOQ estimate, we then focused on samples acquisition of which passed the 500'000 events, according to ELN guidelines. Among 182/261 (69.7%) cases with > 500'000 MNC events as denominator, LODneg/LODpos-LOQneg and LOQpos subgroups were clearly distinct in terms of OS (2-years OS of 83.5% vs. 69.4%, p=0.009). [FIGURE 1B] Similarly, also when selecting those patients (158/261 [60.5%]) whose acquisition passed 500'000 CD45+ events, LODneg/LODpos-LOQneg and LOQpos showed a different behavior with 2-years OS of 86.7% vs. 69.0%, respectively (p=0.004). [FIGURE 1C] Finally, when considering the interaction of the 3 LOD-LOQ categories with possible post-remissional strategies, LODneg/LODpos-LOQneg patients submitted to autologous stem cell transplant showed the best 2-years OS (88.9%) as compared to all the other categories (allogeneic stem cells transplant and no graft-based treatments) (p=0.026). Summary/Conclusion: In conclusion, the use of LOD-LOQ method results in a more sensitive detection of MRD that, in turn, translates in a more accurate recognition of patients with different prognosis. Actually, such an approach allowed to dissect even further the category of patients called MRDneg according to the AML1310 protocol definition, since MRDneg subjects who belonged to a "true negative" LOD-LOQ sub-group [LODneg/LODpos-LOQneg] had a better outcome than the other MRDneg ones. This MRD approach could serve as a useful tool to personalize post-remission strategy in intensively treated AML patients, through selection of high-quality remission patients who may benefit from less intensive post-consolidation therapies. Disclosures Voso: Bristol Myers Squibb: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding. Venditti:Novartis: Consultancy, Honoraria, Other: TRAVEL, ACCOMMODATIONS, EXPENSES (paid by any for-profit health care company); Pfizer: Consultancy, Honoraria, Other: TRAVEL, ACCOMMODATIONS, EXPENSES (paid by any for-profit health care company), Speakers Bureau; Amgen: Consultancy, Honoraria, Other: TRAVEL, ACCOMMODATIONS, EXPENSES (paid by any for-profit health care company); Jazz: Consultancy, Honoraria, Other: TRAVEL, ACCOMMODATIONS, EXPENSES (paid by any for-profit health care company); AbbVie: Consultancy, Honoraria, Other: TRAVEL, ACCOMODATIONS, EXPENSES (paid by any for-profit health care company); Janssen: Consultancy, Honoraria, Other: TRAVEL, ACCOMODATIONS, EXPENSES (paid by any for-profit health care company).

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Ghouti, L., N. Carrere, R. Guimbaud, J. Selves, G. Portier, and B. Pradere. "Chirurgie à visée curative des récidives locorégionales des cancers du rectum (RLCR). Expérience du CHU de Toulouse (276)." Journal de Chirurgie Viscérale 147, no. 4 (September 2010): 16. http://dx.doi.org/10.1016/s1878-786x(10)70037-1.

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SHAHEEN, KAMEL M., and SOMESHWAR C. GUPTA. "PERFORMANCE RELIABILITY OF DS-CDMA MOBILE COMMUNICATION SYSTEM." International Journal of Reliability, Quality and Safety Engineering 03, no. 04 (December 1996): 305–24. http://dx.doi.org/10.1142/s021853939600020x.

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Applications of DS-CDMA in mobile communication systems, in forward link and reverse link, imply certain precautions against near–far effect (NFE), multi-access (co-channel) interference (MAI/CCI), and multipath fading. In this paper, two multi-user detection schemes are proposed to enhance the reliability of DS-CDMA system against NFE and MAI for both reverse link and forward link applications. The first scheme, reverse link multistage CCI cancellation (RLCCI) scheme, is derived for a single path channel model and is based on minimization of estimation error between the received signal and its projections on spreading sequences subspace. The second scheme, forward link CCI (FLCCI) cancellation scheme is based on keeping a simple yet robust decoder at the mobile station (MS), reducing the negative impact of CCI, and enhancing CCI positive contributions. FLCCI minimizes the negative impact of CCI by adjusting the magnitudes of vulnerable spreading codes to compensate in advance for CCI losses. Block diagrams, mathematical models, performance analysis and reliability of both cancellation schemes against NFE, MAI, and external noise are discussed in details. The improvements in BER and overall performance are evaluated using Monte Carlo simulation for both schemes.

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Kubo, Isao, Paulo C. Vieira, and Katsuya Fukuhara. "Efficient Isolation of the Insect Growth Inhibitory Flavone Glycoside Rutin from two Tropical Medicinal Plants by Rotation Locular Countercurrent Chromatography (RLCC)." Journal of Liquid Chromatography 13, no. 12 (July 1990): 2441–48. http://dx.doi.org/10.1080/01483919008049044.

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Abdullah, Piter, and Suseno Suseno. "FUNGSI INTERMEDIASI PERBANKAN DI DAERAH: PENGUKURAN DAN IDENTIFIKASI FAKTOR-FAKTOR YANG MEMPENGARUHI." Buletin Ekonomi Moneter dan Perbankan 5, no. 4 (June 17, 2004): 43–63. http://dx.doi.org/10.21098/bemp.v5i4.317.

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The implementation of the Law No 22 and 25 in 1999 has been recognized as starting point for Indonesia in pursuing a comprehensive and ambitious decentralization program. Decentralization in further step has changed many things including people’s perception especially on the role of regional banks. For some extend the existing regional banks have been claimed as the main cause for “capital flight” from one region to other regions. LDR is used as the only one parameter for claiming that regional banks do not play its role as the intermediary institution and caused the “capital flight”.This paper, derived from the study of the effectiveness of regional banking conducted by PPSK BI, addressed the issue how regional banking should be assessed and what factors affect its effectiveness as intermediary institution. One of the findings of this study is that LDR should not be used as the only one parameter for the effectiveness of regional banks intermediary function. To assess whether regional bank have played its role effectively or not, this study proposed 3 other parameters: RLCR, TLCR and R2. Another important finding of this study is that banking decentralization in term of changes from branch office banking into unit office banking will affect positively the intermediation function of regional bank.

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Khoshdast, Hamid, Alireza Gholami, Ahmad Hassanzadeh, Tomasz Niedoba, and Agnieszka Surowiak. "Advanced Simulation of Removing Chromium from a Synthetic Wastewater by Rhamnolipidic Bioflotation Using Hybrid Neural Networks with Metaheuristic Algorithms." Materials 14, no. 11 (May 27, 2021): 2880. http://dx.doi.org/10.3390/ma14112880.

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This work aims at presenting an advanced simulation approach for a novel rhamnolipidic-based bioflotation process to remove chromium from wastewater. For this purpose, the significance of key influential operating variables including initial solution pH (2, 4, 6, 8, 10 and 12), rhamnolipid to chromium ratio (RL:Cr = 0.010, 0.025, 0.050, 0.075 and 0.100), reductant (Fe) to chromium ratio (Fe:Cr of 0.5, 1.0, 1.5, 2.0, 2.5, 3.0), and air flowrate (50, 100, 150, 200 and 250 mL/min) were investigated and evaluated using Analysis of Variance (ANOVA) method. The RL as both collector and frother was produced using a pure strain of Pseudomonas aeruginosa MA01 under specific conditions. The bioflotation tests were carried out within a bubbly regimed column cell with the dimensions of 60 × 5.70 × 0.1 cm. Four optimization techniques based on Artificial Neural Network (ANN) including Cuckoo, genetic, firefly and biogeography-based optimization algorithms were applied to 113 experiments to identify the optimum values of studied factors. The ANOVA results revealed that all four variables influence the bioflotation performance through a non-linear trend. Their influences, except for aeration rate, were found statistically significant (p-value < 0.05), and all parameters followed the normal distribution according to Anderson-Darlin (AD) criterion. Maximum chromium removal of about 98% was achieved at pH of 6, rhamnolipid to chromium ratio of 0.05, air flowrate of 150 mL/min, and Fe to Cr ratio of 1.0. Flotation kinetics study indicated that chromium bioflotation follows the first-order kinetic model with a rate of 0.023 sec−1. According to the statistical assessment of the model accuracy, the firefly algorithm (FFA) with a structure of 4-9-1 yielded the highest level of reliability with the mean squared, root mean squared, percentage errors and correlation coefficient values of test-data of 0.0038, 0.0617, 3.08% and 96.92%, respectively. These values were evidences of the consistency of the well-structured ANN method to simulate the process.

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Liu, Shenglong, Huan Liu, Chen Shen, Wei Fang, Yazhong Xiao, and Zemin Fang. "Comparison of performances of different fungal laccases in delignification and detoxification of alkali-pretreated corncob for bioethanol production." Journal of Industrial Microbiology and Biotechnology 48, no. 1-2 (February 10, 2021). http://dx.doi.org/10.1093/jimb/kuab013.

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Abstract The performance of the alkaline fungal laccase PIE5 (pH 8.5) in the delignification and detoxification of alkali-pretreated corncob to produce bioethanol was evaluated and compared with that of the neutral counterpart (rLcc9, 6.5), with the acidic laccase rLacA (4.0) was used as an independent control. Treatment with the three laccases facilitated bioethanol production compared with their respective controls. The lignin contents of alkali-pretreated corncob reduced from 4.06%, 5.06%, and 7.80% to 3.44%, 3.95%, and 5.03%, after PIE5, rLcc9, and rLacA treatment, respectively. However, the performances of the laccases were in the order rLacA > rLcc9 > PIE5 in terms of decreasing total phenol concentration (0.18, 0.36, and 0.67 g/l), boosting ethanol concentration (8.02, 7.51, and 7.31 g/l), and volumetric ethanol productivity (1.34, 0.94, and 0.91 g/l hr), and shortening overall fermentation time. Our results would inform future attempts to improve laccases for ethanol production. Furthermore, based on our data and the fact that additional procedures, such as pH adjustment, are needed during neutral/alkaline fungal laccase treatment, we suggest acidic fungal laccases may be a better choice than neutral/alkaline fungal laccases in bioethanol production.

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Sadeghian, Fatemeh, Abdolhosein Haddad, Soheil Jahandari, Haleh Rasekh, and Togay Ozbakkaloglu. "Effects of electrokinetic phenomena on the load-bearing capacity of different steel and concrete piles: A small-scale experimental study." Canadian Geotechnical Journal, July 28, 2020. http://dx.doi.org/10.1139/cgj-2019-0650.

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To date, the electrokinetic (EK) method has only been used to increase the bearing ca-pacity of steel piles. This study analysed the impact of EK on the bearing capacity of rein-forced cement concrete piles (RCCP), reinforced lime-cement concrete piles (RLCCP), and steel piles (SP) located in kaolin clay. The performance of four different cathodes was also evaluated, and the iron electrode was found to be the most effective cathode for using in EK process. Unlike RLCCP, the bearing capacity of 7-day cured RCCP with 5-day EK decreased due to corrosion in the pile body. However, the addition of lime to RCCP signif-icantly increased the pile bearing capacity by 57.8% with 8-day EK and prevented damage and corrosion in the pile body. It is concluded that EK can effectively increase the bearing capacity of both metallic and even concrete piles.

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Journal articles on the topic 'RLCCr'

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