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Journal articles on the topic 'RNA: DNA hybrides'

Author: Grafiati

Published: 25 May 2024

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1

Yang, Xuan, Binyuan Zhai, Shunxin Wang, et al. "RNA-DNA hybrids regulate meiotic recombination." Cell Reports 37, no. 10 (2021): 110097. http://dx.doi.org/10.1016/j.celrep.2021.110097.

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2

Kamath-Loeb, Ashwini S., Amnon Hizi, John Tabone, Marjorie S. Solomon, and Lawrence A. Loeb. "Inefficient Repair of RNA . DNA Hybrids." European Journal of Biochemistry 250, no. 2 (1997): 492–501. http://dx.doi.org/10.1111/j.1432-1033.1997.0492a.x.

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3

Waldron, Denise. "RNA–DNA hybrids: double-edged swords." Nature Reviews Genetics 18, no. 1 (2016): 3. http://dx.doi.org/10.1038/nrg.2016.153.

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4

Hall, Kathleen B. "NMR spectroscopy of DNA/RNA hybrids." Current Opinion in Structural Biology 3, no. 3 (1993): 336–39. http://dx.doi.org/10.1016/s0959-440x(05)80103-4.

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5

Kim, Joung Sug, Junghyun Park, Jang Hyeon Choi, Seungjae Kang, and Nokyoung Park. "RNA–DNA hybrid nano-materials for highly efficient and long lasting RNA interference effect." RSC Advances 13, no. 5 (2023): 3139–46. http://dx.doi.org/10.1039/d2ra06249f.

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A new RNAi approach was developed using an X-RDNA and Ri-Dgel. The nanostructured materials of dsRNA–DNA hybrids showed higher efficient and longer lasting RNA interference effect compared with conventional dsRNA.

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6

Di, Lin, Yusi Fu, Yue Sun, et al. "RNA sequencing by direct tagmentation of RNA/DNA hybrids." Proceedings of the National Academy of Sciences 117, no. 6 (2020): 2886–93. http://dx.doi.org/10.1073/pnas.1919800117.

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Transcriptome profiling by RNA sequencing (RNA-seq) has been widely used to characterize cellular status, but it relies on second-strand complementary DNA (cDNA) synthesis to generate initial material for library preparation. Here we use bacterial transposase Tn5, which has been increasingly used in various high-throughput DNA analyses, to construct RNA-seq libraries without second-strand synthesis. We show that Tn5 transposome can randomly bind RNA/DNA heteroduplexes and add sequencing adapters onto RNA directly after reverse transcription. This method, Sequencing HEteRo RNA-DNA-hYbrid (SHERR

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7

Paull, Tanya T. "RNA–DNA hybrids and the convergence with DNA repair." Critical Reviews in Biochemistry and Molecular Biology 54, no. 4 (2019): 371–84. http://dx.doi.org/10.1080/10409238.2019.1670131.

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8

Huang, Yuegao, Congju Chen, and Irina M. Russu. "Structural Energetics of Two RNA-DNA Hybrids." Biophysical Journal 96, no. 3 (2009): 578a. http://dx.doi.org/10.1016/j.bpj.2008.12.3022.

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9

Vydzhak, Olga, Brian Luke, and Natalie Schindler. "Non-coding RNAs at the Eukaryotic rDNA Locus: RNA–DNA Hybrids and Beyond." Journal of Molecular Biology 432, no. 15 (2020): 4287–304. http://dx.doi.org/10.1016/j.jmb.2020.05.011.

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10

Aguilera, Andrés, and Belén Gómez-González. "DNA–RNA hybrids: the risks of DNA breakage during transcription." Nature Structural & Molecular Biology 24, no. 5 (2017): 439–43. http://dx.doi.org/10.1038/nsmb.3395.

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11

Ozdemir, Ahmet Y., Timur Rusanov, Tatiana Kent, Labiba A. Siddique та Richard T. Pomerantz. "Polymerase θ-helicase efficiently unwinds DNA and RNA-DNA hybrids". Journal of Biological Chemistry 293, № 14 (2018): 5259–69. http://dx.doi.org/10.1074/jbc.ra117.000565.

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12

Kolasa, Kimberly A., Janet R. Morrow, and Arun P. Sharma. "Trivalent lanthanide ions do not cleave RNA in DNA-RNA hybrids." Inorganic Chemistry 32, no. 19 (1993): 3983–84. http://dx.doi.org/10.1021/ic00071a002.

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13

Wang, Isabel X., Christopher Grunseich, Jennifer Fox, et al. "Human proteins that interact with RNA/DNA hybrids." Genome Research 28, no. 9 (2018): 1405–14. http://dx.doi.org/10.1101/gr.237362.118.

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14

Pires, Vanessa Borges, Nina Lohner, Tina Wagner, et al. "RNA-DNA hybrids prevent resection at dysfunctional telomeres." Cell Reports 42, no. 2 (2023): 112077. http://dx.doi.org/10.1016/j.celrep.2023.112077.

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15

Shiels, Jerome C., Bozidar Jerkovic, Anne M. Baranger, and Philip H. Bolton. "RNA–DNA Hybrids Containing Damaged DNA are Substrates for RNase H." Bioorganic & Medicinal Chemistry Letters 11, no. 19 (2001): 2623–26. http://dx.doi.org/10.1016/s0960-894x(01)00527-3.

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16

Crossley, Magdalena P., Michael J. Bocek, Stephan Hamperl, Tomek Swigut, and Karlene A. Cimprich. "qDRIP: a method to quantitatively assess RNA–DNA hybrid formation genome-wide." Nucleic Acids Research 48, no. 14 (2020): e84-e84. http://dx.doi.org/10.1093/nar/gkaa500.

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Abstract R-loops are dynamic, co-transcriptional nucleic acid structures that facilitate physiological processes but can also cause DNA damage in certain contexts. Perturbations of transcription or R-loop resolution are expected to change their genomic distribution. Next-generation sequencing approaches to map RNA–DNA hybrids, a component of R-loops, have so far not allowed quantitative comparisons between such conditions. Here, we describe quantitative differential DNA–RNA immunoprecipitation (qDRIP), a method combining synthetic RNA–DNA-hybrid internal standards with high-resolution, strand-

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17

Figiel, Małgorzata, Hyongi Chon, Susana M. Cerritelli, Magdalena Cybulska, Robert J. Crouch, and Marcin Nowotny. "The Structural and Biochemical Characterization of Human RNase H2 Complex Reveals the Molecular Basis for Substrate Recognition and Aicardi-Goutières Syndrome Defects." Journal of Biological Chemistry 286, no. 12 (2010): 10540–50. http://dx.doi.org/10.1074/jbc.m110.181974.

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RNase H2 cleaves RNA sequences that are part of RNA/DNA hybrids or that are incorporated into DNA, thus, preventing genomic instability and the accumulation of aberrant nucleic acid, which in humans induces Aicardi-Goutières syndrome, a severe autoimmune disorder. The 3.1 Å crystal structure of human RNase H2 presented here allowed us to map the positions of all 29 mutations found in Aicardi-Goutières syndrome patients, several of which were not visible in the previously reported mouse RNase H2. We propose the possible effects of these mutations on the protein stability and function. Bacterial

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18

Santamarı́a, David, Guillermo de la Cueva, Marı́a Luisa Martı́nez-Robles, Dora B. Krimer, Pablo Hernández, and Jorge B. Schvartzman. "DnaB Helicase Is Unable to Dissociate RNA-DNA Hybrids." Journal of Biological Chemistry 273, no. 50 (1998): 33386–96. http://dx.doi.org/10.1074/jbc.273.50.33386.

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19

de Vroom, E., H. C. P. F. Roelen, C. P. Saris, T. N. W. Budding, G. A. van der Marel, and J. H. van Boom. "Preparation of covalently linked DNA-RNA hybrids and arabinocytidine containing DNA fragments." Nucleic Acids Research 16, no. 7 (1988): 2987–3003. http://dx.doi.org/10.1093/nar/16.7.2987.

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20

Zhan, Yilin, and Giovanni Zocchi. "Flexibility of DNA/PNA, DNA/LNA, DNA/RNA hybrids measured with a nanoscale transducer." EPL (Europhysics Letters) 119, no. 4 (2017): 48005. http://dx.doi.org/10.1209/0295-5075/119/48005.

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21

Xu, B., and D. A. Clayton. "A persistent RNA-DNA hybrid is formed during transcription at a phylogenetically conserved mitochondrial DNA sequence." Molecular and Cellular Biology 15, no. 1 (1995): 580–89. http://dx.doi.org/10.1128/mcb.15.1.580.

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Critical features of the mitochondrial leading-strand DNA replication origin are conserved from Saccharomyces cerevisiae to humans. These include a promoter and a downstream GC-rich sequence block (CSBII) that encodes rGs within the primer RNA. During in vitro transcription at yeast mitochondrial replication origins, there is stable and persistent RNA-DNA hybrid formation that begins at the 5' end of the rG region. The short rG-dC sequence is the necessary and sufficient nucleic acid element for establishing stable hybrids, and the presence of rGs within the RNA strand of the RNA-DNA hybrid is

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22

Gillespie, F. P., T. H. Hong, and J. M. Eisenstadt. "Transcription and translation of mitochondrial DNA in interspecific somatic cell hybrids." Molecular and Cellular Biology 6, no. 6 (1986): 1951–57. http://dx.doi.org/10.1128/mcb.6.6.1951-1957.1986.

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We examined the mitochondrial transcription and translation products of somatic cell hybrids constructed by the fusion of Chinese hamster and mouse cells. The hybrid cell lines OAC-k, OAC-l, and OAC-m contain approximately equal amounts of hamster and mouse mitochondrial DNA and produced mitochondrial rRNA from both parental species in the same ratio. Cell lines OAC-k, OAC-l, and OAC-m also produced poly(A)+ mouse mitochondrial RNA transcripts comparable in complexity and quantity to poly(A)+ RNA from the mouse parent. However, the overall level of poly(A)+ hamster mitochondrial RNA from these

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23

Gillespie, F. P., T. H. Hong, and J. M. Eisenstadt. "Transcription and translation of mitochondrial DNA in interspecific somatic cell hybrids." Molecular and Cellular Biology 6, no. 6 (1986): 1951–57. http://dx.doi.org/10.1128/mcb.6.6.1951.

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We examined the mitochondrial transcription and translation products of somatic cell hybrids constructed by the fusion of Chinese hamster and mouse cells. The hybrid cell lines OAC-k, OAC-l, and OAC-m contain approximately equal amounts of hamster and mouse mitochondrial DNA and produced mitochondrial rRNA from both parental species in the same ratio. Cell lines OAC-k, OAC-l, and OAC-m also produced poly(A)+ mouse mitochondrial RNA transcripts comparable in complexity and quantity to poly(A)+ RNA from the mouse parent. However, the overall level of poly(A)+ hamster mitochondrial RNA from these

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24

Turner, K. B., H. Y. Yi-Brunozzi, R. G. Brinson, J. P. Marino, D. Fabris, and S. F. J. Le Grice. "SHAMS: Combining chemical modification of RNA with mass spectrometry to examine polypurine tract-containing RNA/DNA hybrids." RNA 15, no. 8 (2009): 1605–13. http://dx.doi.org/10.1261/rna.1615409.

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25

Tseng, R. W., and N. H. Acheson. "Use of a novel S1 nuclease RNA-mapping technique to measure efficiency of transcription termination on polyomavirus DNA." Molecular and Cellular Biology 6, no. 5 (1986): 1624–32. http://dx.doi.org/10.1128/mcb.6.5.1624-1632.1986.

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We devised a strategy to measure the efficiency of transcription termination in vivo by RNA polymerase on polyomavirus DNA. Pulse-labeled nuclear RNA was hybridized with a single-stranded polyomavirus DNA fragment which spans the transcription initiation region. Hybrids were treated with RNase, bound to nitrocellulose filters, eluted with S1 nuclease, and analyzed by gel electrophoresis. The ratio of full-length to less-than-full-length DNA-RNA hybrids was used to calculate transcription termination frequency. We found that 50% of the polymerases terminated per traverse of the L DNA strand dur

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26

Tseng, R. W., and N. H. Acheson. "Use of a novel S1 nuclease RNA-mapping technique to measure efficiency of transcription termination on polyomavirus DNA." Molecular and Cellular Biology 6, no. 5 (1986): 1624–32. http://dx.doi.org/10.1128/mcb.6.5.1624.

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We devised a strategy to measure the efficiency of transcription termination in vivo by RNA polymerase on polyomavirus DNA. Pulse-labeled nuclear RNA was hybridized with a single-stranded polyomavirus DNA fragment which spans the transcription initiation region. Hybrids were treated with RNase, bound to nitrocellulose filters, eluted with S1 nuclease, and analyzed by gel electrophoresis. The ratio of full-length to less-than-full-length DNA-RNA hybrids was used to calculate transcription termination frequency. We found that 50% of the polymerases terminated per traverse of the L DNA strand dur

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27

Kratochvílová, Irena, Martin Vala, Martin Weiter, et al. "Charge transfer through DNA/DNA duplexes and DNA/RNA hybrids: Complex theoretical and experimental studies." Biophysical Chemistry 180-181 (October 2013): 127–34. http://dx.doi.org/10.1016/j.bpc.2013.07.009.

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28

Kim, Nayun, Jang-Eun Cho, Yue C. Li, and Sue Jinks-Robertson. "RNA∶DNA Hybrids Initiate Quasi-Palindrome-Associated Mutations in Highly Transcribed Yeast DNA." PLoS Genetics 9, no. 11 (2013): e1003924. http://dx.doi.org/10.1371/journal.pgen.1003924.

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29

Lopata, M. A., B. Sollner-Webb, and D. W. Cleveland. "Surprising S1-resistant trimolecular hybrids: potential complication in interpretation of S1 mapping analyses." Molecular and Cellular Biology 5, no. 10 (1985): 2842–46. http://dx.doi.org/10.1128/mcb.5.10.2842-2846.1985.

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Although the technique of S1 mapping is a powerful analytical tool for the analysis of RNA, we now report a surprising complication involving a trimolecular hybrid between two RNA species and a single DNA probe molecule which, if unrecognized, can lead to misleading interpretations. We document that such trimolecular hybrids can be efficiently formed under some hybridization conditions and that the probe DNA sequence at the junction of the two RNA molecules can be remarkably stable to digestion with S1. Trimolecular hybrids can arise in any instance whenever a distal region of an end-labeled D

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30

Lopata, M. A., B. Sollner-Webb, and D. W. Cleveland. "Surprising S1-resistant trimolecular hybrids: potential complication in interpretation of S1 mapping analyses." Molecular and Cellular Biology 5, no. 10 (1985): 2842–46. http://dx.doi.org/10.1128/mcb.5.10.2842.

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Although the technique of S1 mapping is a powerful analytical tool for the analysis of RNA, we now report a surprising complication involving a trimolecular hybrid between two RNA species and a single DNA probe molecule which, if unrecognized, can lead to misleading interpretations. We document that such trimolecular hybrids can be efficiently formed under some hybridization conditions and that the probe DNA sequence at the junction of the two RNA molecules can be remarkably stable to digestion with S1. Trimolecular hybrids can arise in any instance whenever a distal region of an end-labeled D

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31

Balk, Bettina, André Maicher, Martina Dees, et al. "Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence." Nature Structural & Molecular Biology 20, no. 10 (2013): 1199–205. http://dx.doi.org/10.1038/nsmb.2662.

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32

Gómez-González, Belén, Sonia Barroso, Emilia Herrera-Moyano, and Andrés Aguilera. "Spontaneous DNA-RNA hybrids: differential impacts throughout the cell cycle." Cell Cycle 19, no. 5 (2020): 525–31. http://dx.doi.org/10.1080/15384101.2020.1728015.

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33

Wang, Jiou, Aaron R. Haeusler, and Eric AJ Simko. "Emerging role of RNA•DNA hybrids in C9orf72-linked neurodegeneration." Cell Cycle 14, no. 4 (2015): 526–32. http://dx.doi.org/10.1080/15384101.2014.995490.

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34

Strzyz, Paulina. "RNA–DNA hybrids: a double-edged sword in genomic stability." Nature Reviews Molecular Cell Biology 17, no. 12 (2016): 740. http://dx.doi.org/10.1038/nrm.2016.155.

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35

Palancade, Benoit, and Rodney Rothstein. "The Ultimate (Mis)match: When DNA Meets RNA." Cells 10, no. 6 (2021): 1433. http://dx.doi.org/10.3390/cells10061433.

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RNA-containing structures, including ribonucleotide insertions, DNA:RNA hybrids and R-loops, have recently emerged as critical players in the maintenance of genome integrity. Strikingly, different enzymatic activities classically involved in genome maintenance contribute to their generation, their processing into genotoxic or repair intermediates, or their removal. Here we review how this substrate promiscuity can account for the detrimental and beneficial impacts of RNA insertions during genome metabolism. We summarize how in vivo and in vitro experiments support the contribution of DNA polym

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36

E, Beeram. "Mini review on Protein – Protein and DNA/RNA – protein interactions in biology." Asploro Journal of Biomedical and Clinical Case Reports 2, no. 2 (2019): 82–83. http://dx.doi.org/10.36502/2019/asjbccr.6165.

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RNase H1 generally processes the RNA- DNA hybrids through non specific interaction between HBD and the ds RNA/DNA hybrid. There are no direct protein- protein interactions between the hybrid and HBD of RNase H1. The DNA binding region is highly conserved compared to RNA binding region and the Kd for RNA/DNA hybrid is less compared to ds RNA than to that of ds DNA [1]. HBD increases the processivity of RNase H1 and mutations in RNA binding region is tolerated compared to DBR. The RNA interacts between ɑ2 and β3 region with in the loop and with the protein in shallower minor groove.

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37

Kojima, Kenji, Misato Baba, Motoki Tsukiashi, Takuto Nishimura, and Kiyoshi Yasukawa. "RNA/DNA structures recognized by RNase H2." Briefings in Functional Genomics 18, no. 3 (2018): 169–73. http://dx.doi.org/10.1093/bfgp/ely024.

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Abstract Ribonuclease H (RNase H) [EC 3.1.26.4] is an enzyme that specifically degrades RNA from RNA/DNA hybrids. Since its discovery in 1969, the enzyme has been extensively studied for its catalytic mechanism and physiological role. RNase H has been classified into two major families, Type 1 and Type 2. Type 1 enzymes are designated RNase HI in prokaryotes and RNase H1 in eukaryotes, while Type 2 enzymes are designated RNase HII in prokaryotes and RNase H2 in eukaryotes. Type 2 enzymes are able to cleave the 5′-phosphodiester bond of one ribonucleotide embedded in a DNA double strand. Recent

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38

Suresh, Gorle, and U. Deva Priyakumar. "DNA–RNA hybrid duplexes with decreasing pyrimidine content in the DNA strand provide structural snapshots for the A- to B-form conformational transition of nucleic acids." Phys. Chem. Chem. Phys. 16, no. 34 (2014): 18148–55. http://dx.doi.org/10.1039/c4cp02478h.

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39

Lee, Hyunjee, HyeokJin Cho, Jooyoung Kim, et al. "RNase H is an exo- and endoribonuclease with asymmetric directionality, depending on the binding mode to the structural variants of RNA:DNA hybrids." Nucleic Acids Research 50, no. 4 (2021): 1801–14. http://dx.doi.org/10.1093/nar/gkab1064.

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Abstract RNase H is involved in fundamental cellular processes and is responsible for removing the short stretch of RNA from Okazaki fragments and the long stretch of RNA from R-loops. Defects in RNase H lead to embryo lethality in mice and Aicardi-Goutieres syndrome in humans, suggesting the importance of RNase H. To date, RNase H is known to be a non-sequence-specific endonuclease, but it is not known whether it performs other functions on the structural variants of RNA:DNA hybrids. Here, we used Escherichia coli RNase H as a model, and examined its catalytic mechanism and its substrate reco

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40

Bansal, M., J. S. Lee, J. W. Kozarich, and J. Stubbe. "Mechanistic analyses of site-specific degradation in DNA-RNA hybrids by prototypic DNA cleavers." Nucleic Acids Research 25, no. 9 (1997): 1836–45. http://dx.doi.org/10.1093/nar/25.9.1836.

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41

Bansal, M., J. W. Kozarich, and J. Stubbe. "Effects of hypoxanthine substitution on bleomycin-mediated DNA strand degradation in DNA-RNA hybrids." Nucleic Acids Research 25, no. 9 (1997): 1846–53. http://dx.doi.org/10.1093/nar/25.9.1846.

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42

Coutlée, Francois, Linda Bobo, Kumudini Mayur, Robert H. Yolken, and Raphael P. Viscidi. "Immunodetection of DNA with biotinylated RNA probes: A study of reactivity of a monoclonal antibody to DNA-RNA hybrids." Analytical Biochemistry 181, no. 1 (1989): 96–105. http://dx.doi.org/10.1016/0003-2697(89)90399-0.

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43

Kapali, Ojashpi Singh, and Vladimir Kuznetsov. "Abstract 407: RNA:DNA hybrid/R-loop determinants variation in distinct basal-like breast cancer cells." Cancer Research 84, no. 6_Supplement (2024): 407. http://dx.doi.org/10.1158/1538-7445.am2024-407.

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Abstract Introduction: Despite progress in treatment methods and diagnosis, breast cancer remains one of the world's leading cancers causes of death. Among the various subtypes, basal-like breast cancer (BLBC) is highly diverse, low differentiated, most aggressive form with poor prognosis. Co-translational R-loops are created by combining G-rich RNA with complementary C-rich DNA (RNA: DNA hybrid), which creates a three-stranded nucleic acid structure. R-loops are often associated with genome instability and aggressiveness of cancers. However, their role in the diversity of BLBC remains controv

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44

Meng, Xiangzhou, Hung Quang Dang, and Geoffrey M. Kapler. "Developmentally Programmed Switches in DNA Replication: Gene Amplification and Genome-Wide Endoreplication in Tetrahymena." Microorganisms 11, no. 2 (2023): 491. http://dx.doi.org/10.3390/microorganisms11020491.

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Locus-specific gene amplification and genome-wide endoreplication generate the elevated copy number of ribosomal DNA (rDNA, 9000 C) and non-rDNA (90 C) chromosomes in the developing macronucleus of Tetrahymena thermophila. Subsequently, all macronuclear chromosomes replicate once per cell cycle during vegetative growth. Here, we describe an unanticipated, programmed switch in the regulation of replication initiation in the rDNA minichromosome. Early in development, the 21 kb rDNA minichromosome is preferentially amplified from 2 C to ~800 C from well-defined origins, concurrent with genome-wid

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45

Nava, Giulia Maria, Lavinia Grasso, Sarah Sertic, Achille Pellicioli, Marco Muzi Falconi, and Federico Lazzaro. "One, No One, and One Hundred Thousand: The Many Forms of Ribonucleotides in DNA." International Journal of Molecular Sciences 21, no. 5 (2020): 1706. http://dx.doi.org/10.3390/ijms21051706.

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In the last decade, it has become evident that RNA is frequently found in DNA. It is now well established that single embedded ribonucleoside monophosphates (rNMPs) are primarily introduced by DNA polymerases and that longer stretches of RNA can anneal to DNA, generating RNA:DNA hybrids. Among them, the most studied are R-loops, peculiar three-stranded nucleic acid structures formed upon the re-hybridization of a transcript to its template DNA. In addition, polyribonucleotide chains are synthesized to allow DNA replication priming, double-strand breaks repair, and may as well result from the d

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46

Jang, Yumi, Zeinab Elsayed, Rebeka Eki, et al. "Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites." Proceedings of the National Academy of Sciences 117, no. 10 (2020): 5329–38. http://dx.doi.org/10.1073/pnas.1913280117.

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Accumulating evidence suggests participation of RNA-binding proteins with intrinsically disordered domains (IDPs) in the DNA damage response (DDR). These IDPs form liquid compartments at DNA damage sites in a poly(ADP ribose) (PAR)-dependent manner. However, it is greatly unknown how the IDPs are involved in DDR. We have shown previously that one of the IDPs RBM14 is required for the canonical nonhomologous end joining (cNHEJ). Here we show that RBM14 is recruited to DNA damage sites in a PARP- and RNA polymerase II (RNAPII)-dependent manner. Both KU and RBM14 are required for RNAPII-dependent

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47

Hu, Yan, Henrietta W. Bennett, Na Liu, et al. "RNA–DNA Hybrids Support Recombination-Based Telomere Maintenance in Fission Yeast." Genetics 213, no. 2 (2019): 431–47. http://dx.doi.org/10.1534/genetics.119.302606.

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48

Happ, C. Scalfi, E. Happ, A. M. Gronenborn, and G. M. Clore. "Synthesis and1-NMR Studies of DNA-RNA Hybrids for Structural Analysis." Nucleosides and Nucleotides 7, no. 5-6 (1988): 733–36. http://dx.doi.org/10.1080/07328318808056320.

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49

Arbona, Maria, Juan Bautista Cuenca, and Rosa Frutos. "Stress response in Drosophila subobscura: DNA-RNA hybrids and transcriptional activity." Biology of the Cell 75, no. 3 (1992): 187–95. http://dx.doi.org/10.1016/0248-4900(92)90140-v.

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50

Krstulović, Luka, Ivana Stolić, Marijana Jukić, et al. "New quinoline-arylamidine hybrids: Synthesis, DNA/RNA binding and antitumor activity." European Journal of Medicinal Chemistry 137 (September 2017): 196–210. http://dx.doi.org/10.1016/j.ejmech.2017.05.054.

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