Relevant bibliographies by topics / RNA G-Quadruplexes

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'RNA G-Quadruplexes'

Author: Grafiati
Published: 30 November 2024
Last updated: 31 July 2025

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Journal articles on the topic "RNA G-Quadruplexes"

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Agarwal, Tani, Gopal Jayaraj, Satya Prakash Pandey, Prachi Agarwala, and Souvik Maiti. "RNA G-Quadruplexes: G-quadruplexes with “U” Turns." Current Pharmaceutical Design 18, no. 14 (2012): 2102–11. http://dx.doi.org/10.2174/138161212799958468.

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Zhang, Rongxin, Yajun Liu, Xingxing Zhang, et al. "Detecting and Profiling Endogenous RNA G-Quadruplexes in the Human Transcriptome." International Journal of Molecular Sciences 22, no. 15 (2021): 8012. http://dx.doi.org/10.3390/ijms22158012.

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G-quadruplexes are the non-canonical nucleic acid structures that are preferentially formed in G-rich regions. This structure has been shown to be associated with many biological functions. Regardless of the broad efforts on DNA G-quadruplexes, we still have limited knowledge on RNA G-quadruplexes, especially in a transcriptome-wide manner. Herein, by integrating the DMS-seq and the bioinformatics pipeline, we profiled and depicted the RNA G-quadruplexes in the human transcriptome. The genes that contain RNA G-quadruplexes in their specific regions are significantly related to immune pathways
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Li, Wei, Weiwu Zeng, Yi Chen, et al. "Biotinylation and isolation of an RNA G-quadruplex based on its peroxidase-mimicking activity." Analyst 144, no. 15 (2019): 4472–76. http://dx.doi.org/10.1039/c9an00353c.

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Millevoi, Stefania, Hervé Moine, and Stéphan Vagner. "G-quadruplexes in RNA biology." Wiley Interdisciplinary Reviews: RNA 3, no. 4 (2012): 495–507. http://dx.doi.org/10.1002/wrna.1113.

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Koralewska, Natalia, Agnieszka Szczepanska, Kinga Ciechanowska, et al. "RNA and DNA G-quadruplexes bind to human dicer and inhibit its activity." Cellular and Molecular Life Sciences 78, no. 7 (2021): 3709–24. http://dx.doi.org/10.1007/s00018-021-03795-w.

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AbstractGuanine (G)-rich single-stranded nucleic acids can adopt G-quadruplex structures. Accumulating evidence indicates that G-quadruplexes serve important regulatory roles in fundamental biological processes such as DNA replication, transcription, and translation, while aberrant G-quadruplex formation is linked to genome instability and cancer. Understanding the biological functions played by G-quadruplexes requires detailed knowledge of their protein interactome. Here, we report that both RNA and DNA G-quadruplexes are bound by human Dicer in vitro. Using in vitro binding assays, mutation
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Mestre-Fos, Santi, Petar I. Penev, Suttipong Suttapitugsakul, et al. "G-Quadruplexes in Human Ribosomal RNA." Journal of Molecular Biology 431, no. 10 (2019): 1940–55. http://dx.doi.org/10.1016/j.jmb.2019.03.010.

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Criscuolo, Andrea, Ettore Napolitano, Claudia Riccardi, Domenica Musumeci, Chiara Platella, and Daniela Montesarchio. "Insights into the Small Molecule Targeting of Biologically Relevant G-Quadruplexes: An Overview of NMR and Crystal Structures." Pharmaceutics 14, no. 11 (2022): 2361. http://dx.doi.org/10.3390/pharmaceutics14112361.

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G-quadruplexes turned out to be important targets for the development of novel targeted anticancer/antiviral therapies. More than 3000 G-quadruplex small-molecule ligands have been described, with most of them exerting anticancer/antiviral activity by inducing telomeric damage and/or altering oncogene or viral gene expression in cancer cells and viruses, respectively. For some ligands, in-depth NMR and/or crystallographic studies were performed, providing detailed knowledge on their interactions with diverse G-quadruplex targets. Here, the PDB-deposited NMR and crystal structures of the comple
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Dumetz, Franck, Eugene Yui-Ching Chow, Lynne M. Harris, et al. "G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum." Nucleic Acids Research 49, no. 21 (2021): 12486–501. http://dx.doi.org/10.1093/nar/gkab1095.

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Abstract G-quadruplexes are non-helical secondary structures that can fold in vivo in both DNA and RNA. In human cells, they can influence replication, transcription and telomere maintenance in DNA, or translation, transcript processing and stability of RNA. We have previously showed that G-quadruplexes are detectable in the DNA of the malaria parasite Plasmodium falciparum, despite a very highly A/T-biased genome with unusually few guanine-rich sequences. Here, we show that RNA G-quadruplexes can also form in P. falciparum RNA, using rG4-seq for transcriptome-wide structure-specific RNA probi
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Sanchez-Martin, Victoria, Miguel Soriano, and Jose Antonio Garcia-Salcedo. "Quadruplex Ligands in Cancer Therapy." Cancers 13, no. 13 (2021): 3156. http://dx.doi.org/10.3390/cancers13133156.

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Nucleic acids can adopt alternative secondary conformations including four-stranded structures known as quadruplexes. To date, quadruplexes have been demonstrated to exist both in human chromatin DNA and RNA. In particular, quadruplexes are found in guanine-rich sequences constituting G-quadruplexes, and in cytosine-rich sequences forming i-Motifs as a counterpart. Quadruplexes are associated with key biological processes ranging from transcription and translation of several oncogenes and tumor suppressors to telomeres maintenance and genome instability. In this context, quadruplexes have prom
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Rouleau, Samuel, Jean-Pierre Sehi Glouzon, Andrea Brumwell, Martin Bisaillon, and Jean-Pierre Perreault. "3′ UTR G-quadruplexes regulate miRNA binding." RNA 23, no. 8 (2017): 1172–79. http://dx.doi.org/10.1261/rna.060962.117.

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Dissertations / Theses on the topic "RNA G-Quadruplexes"

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Weldon, Carika, Isabelle Behm-Ansmant, Laurence H. Hurley, et al. "Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA." NATURE PUBLISHING GROUP, 2016. http://hdl.handle.net/10150/623077.

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RNA G-quadruplex (G4) structures are thought to affect biological processes, including translation and pre-mRNA splicing, but it is not possible at present to demonstrate that they form naturally at specific sequences in long functional RNA molecules. We developed a new strategy, footprinting of long 7-deazaguanine-substituted RNAs (FOLDeR), that allows the formation of G4s to be confirmed in long RNAs and under functional conditions.
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Zhang, Amy Yun Qing. "Studies into the formation, kinetics and mechanics of RNA G-quadruplexes." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648124.

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Kumari, Sunita. "Role of RNA G-quadruplexes within 5' UTRs in translation regulation." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612262.

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Reznichenko, Oksana. "Combinatorial chemistry approaches for the development of G-quadruplex DNA and RNA ligands." Thesis, université Paris-Saclay, 2021. http://www.theses.fr/2021UPASF014.

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Les G-quadruplexes (G4s) sont des structures non-canoniques d’acides nucléiques (ADN et ARN) constituées d’au moins deux quartets de guanines. L’une des propriétés importantes des G4s est leur capacité à former des complexes avec de petites molécules exogènes (ligands) et d’influencer ainsi les processus biologiques dans lesquels ils sont impliqués. Ainsi, l’interaction de petites molécules avec certaines structures G4s permettrait de diminuer l’expression de certains oncogènes, d’inhiber la télomérase ou encore d’induire des dommages à l’ADN. Ce travail vise à développer des méthodologies rap
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Bourdon, Sebastien. "Régulation des ARN G-Quadruplexes par les protéines de liaison à l'ARN et leur interaction avec les N6-Méthyladénosines dans les cellules du cancer." Electronic Thesis or Diss., Université de Toulouse (2023-....), 2024. http://www.theses.fr/2024TLSES129.

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Le développement du cancer et la réponse aux traitements sont associés à des variations de la régulation post-transcriptionnelle qui entraîne une modification du protéome qualitativement et/ou quantitativement. La régulation post-transcriptionnelle implique des protéines de liaison à l’ARN (RBP), interagissant avec des éléments cis comme les séquences, les modifications ou les structures de l’ARN. Parmi ces éléments cis, les structures non-canoniques nommées ARN G-Quadruplexes (RG4), et les modifications N6-Méthyladénosines (m6A), jouent un rôle critique dans le modelage post-transcriptionnel
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Ribeiro, Mariana Martins 1984. "G-quadruplex formation enhances splicing efficiency of PAX9 intron 1." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290066.

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Orientadores: Sérgio Roberto Peres Line, Marcelo Rocha Marques<br>Texto em português e inglês<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-24T17:45:16Z (GMT). No. of bitstreams: 1 Ribeiro_MarianaMartins_D.pdf: 2903322 bytes, checksum: 9e0e5e91a22262495ca9bf8ae1d84cec (MD5) Previous issue date: 2014<br>Resumo: G-Quadruplexes são estruturas secundárias presentes nas moléculas de DNA e RNA, os quais são formados pelo empilhamento de G-quartetos (interação de quatro guaninas (G-tratos) delimitadas por ligaç
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Le, Bras Morgane. "Rôle des protéines de liaison à l'ARN hnRNP H et hnRNP F dans les régulations traductionnelles dans les glioblastomes." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30277.

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Le glioblastome multiforme (GBM) est une tumeur cérébrale extrêmement agressive associée à un mauvais pronostic. C'est pourquoi, il apparaît nécessaire d'identifier les mécanismes moléculaires participant au développement des GBM ainsi qu'à leurs résistances aux traitements afin de développer de nouvelles approches thérapeutiques. Récemment, il a été montré que les régulations traductionnelles jouent un rôle fondamental dans les propriétés agressives du GBM. Les protéines de liaison à l'ARN (RBP) sont des acteurs majeurs de ces régulations dont l'expression/activité est altérée dans les GBM. L
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Largy, Eric. "Ciblage d’acides nucléiques G-quadruplexes : synthèse et développement de méthodes pour l’analyse et le criblage de ligands sélectifs multimodaux." Thesis, Paris 11, 2011. http://www.theses.fr/2011PA112257.

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L’objectif de ces travaux de thèse était l’étude des interactions de petites molécules avec les multiples structures de l’ADN quadruplex via i) le développement et l’utilisation d’un test haut-débit pour l’analyse des interactions ligand-ADN quadruplex et le criblage de chimiothèques/ciblothèques et ii) la préparation de composés aux modes d’interactions multiples (empilement/sillon, covalent/non-covalent, etc.), sélectifs (quadruplex vs. duplex et intra-quadruplex) et éventuellement fonctionnalisés (biotine, fluorophore, etc.). La première partie des travaux a été centrée sur le développement
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Zheng, Alice Jia-Li. "How the Epstein-Barr virus-encoded EBNA1 mRNA translation is regulated in cis by its mRNA dynamic structure and its nascent polypeptide." Thesis, Université Paris Cité, 2021. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=3378&f=38122.

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La traduction des ARNm et la production de protéines sont des phénomènes étroitement contrôlés dans la cellule. La séquence de l'ARNm et sa structure, auxquelles sont associées des protéines se liant à l'ARN, ainsi que la qualité de la protéine produite à partir de cet ARNm, évaluée notamment par la voie de contrôle qualité associée aux ribosomes, sont des éléments impliqués dans ce processus majeur pour la cellule. Dans ce domaine, le contrôle de la production de protéine EBNA1 (Epstein-Barr Nuclear Antigen 1) du virus d'Epstein -Barr est un exemple intéressant. La protéine EBNA1 est essentie
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Serikawa, Tatsuo [Verfasser], Jens [Akademischer Betreuer] Kurreck, Jens [Gutachter] Kurreck, Juri [Gutachter] Rappsilber, and Jürgen [Gutachter] Eberle. "Studien zur endogenen Expression von RNA G-Quadruplexen und deren Interaktion mit zellulären Proteinen / Tatsuo Serikawa ; Gutachter: Jens Kurreck, Juri Rappsilber, Jürgen Eberle ; Betreuer: Jens Kurreck." Berlin : Technische Universität Berlin, 2017. http://d-nb.info/1156014328/34.

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Book chapters on the topic "RNA G-Quadruplexes"

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Kharel, Prakash, and Pavel Ivanov. "Structure and Functions of RNA G-quadruplexes." In RNA Technologies. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-36390-0_9.

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Uttamrao, Patil Pranita, Sruthi Sundaresan, and Thenmalarchelvi Rathinavelan. "Structure and Folding Patterns of RNA G-Quadruplexes." In RNA Technologies. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-36390-0_10.

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Lorenz, Ronny, Stephan H. Bernhart, Fabian Externbrink, et al. "RNA Folding Algorithms with G-Quadruplexes." In Advances in Bioinformatics and Computational Biology. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-31927-3_5.

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Pandey, Satyaprakash, Prachi Agarwala, and Souvik Maiti. "Targeting RNA G-Quadruplexes for Potential Therapeutic Applications." In Topics in Medicinal Chemistry. Springer International Publishing, 2017. http://dx.doi.org/10.1007/7355_2016_22.

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Rouleau, Samuel, Rachel Jodoin, Jean-Michel Garant, and Jean-Pierre Perreault. "RNA G-Quadruplexes as Key Motifs of the Transcriptome." In Catalytically Active Nucleic Acids. Springer International Publishing, 2017. http://dx.doi.org/10.1007/10_2017_8.

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Mattay, Johanna. "Probing Techniques of Secondary and Tertiary RNA Structure and a Case Study for RNA G-Quadruplexes." In RNA Technologies. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-36390-0_8.

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Conference papers on the topic "RNA G-Quadruplexes"

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Lorenz, Ronny, and Peter F. Stadler. "Squares in Cycles: Prediction of G-Quadruplexes in Circular RNA Secondary Stuctures." In Simpósio Brasileiro de Bioinformática. Sociedade Brasileira de Computação, 2024. https://doi.org/10.5753/bsb.2024.245308.

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RNA secondary structures, determined by non-crossing base pairs, capture many of the salient features of RNA molecules, explain the free energy of structure formation very accurately, and can be computed efficiently given the sequence information only. G-quadruplexes are compact local structures that have been shown to have important biological function and can be integrated into secondary structure prediction. In recent years circular RNAs have gained considerable interest as a biological relevant subclass of RNAs. While algorithms and tools are available that extend secondary structure predi
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Amato, Jussara, Simona Marzano, Bruno Pagano, et al. "Targeting of telomeric repeat-containing RNA G-quadruplexes: From screening to biophysical and biological characterization of a new hit compound." In 7th International Electronic Conference on Medicinal Chemistry. MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11382.

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