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Journal articles on the topic 'RNA Nanotechnology'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

OHNO, Hirohisa, and Hirohide SAITO. "RNA/RNP Nanotechnology for Biological Applications." Seibutsu Butsuri 56, no. 1 (2016): 023–26. http://dx.doi.org/10.2142/biophys.56.023.

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2

Grabow, Wade W., and Luc Jaeger. "RNA Self-Assembly and RNA Nanotechnology." Accounts of Chemical Research 47, no. 6 (2014): 1871–80. http://dx.doi.org/10.1021/ar500076k.

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3

Lin, Yao-Xin, Yi Wang, Sara Blake, et al. "RNA Nanotechnology-Mediated Cancer Immunotherapy." Theranostics 10, no. 1 (2020): 281–99. http://dx.doi.org/10.7150/thno.35568.

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4

Kim, Jongmin, and Elisa Franco. "RNA nanotechnology in synthetic biology." Current Opinion in Biotechnology 63 (June 2020): 135–41. http://dx.doi.org/10.1016/j.copbio.2019.12.016.

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5

Guo, Peixuan. "The emerging field of RNA nanotechnology." Nature Nanotechnology 5, no. 12 (2010): 833–42. http://dx.doi.org/10.1038/nnano.2010.231.

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6

Weizmann, Yossi, and Ebbe Sloth Andersen. "RNA nanotechnology—The knots and folds of RNA nanoparticle engineering." MRS Bulletin 42, no. 12 (2017): 930–35. http://dx.doi.org/10.1557/mrs.2017.277.

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7

Leung, KaHo, and Yamuna Krishnan. "Dynamic RNA Nanotechnology Enters the CRISPR Toolbox." ACS Central Science 5, no. 7 (2019): 1111–13. http://dx.doi.org/10.1021/acscentsci.9b00550.

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8

Hill, Alyssa C., and Jonathan Hall. "High-order structures from nucleic acids for biomedical applications." Materials Chemistry Frontiers 4, no. 4 (2020): 1074–88. http://dx.doi.org/10.1039/c9qm00638a.

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9

Kumawat, Akshant, Prachi Dapse, Narendra Kumar, et al. "Budding Alliance of Nanotechnology in RNA Interference Therapeutics." Current Pharmaceutical Design 24, no. 23 (2018): 2632–43. http://dx.doi.org/10.2174/1381612824666180807113948.

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RNA interference (RNAi), as a novel technique in which RNA molecules limit or silence the gene expression, is currently a hot research topic for producing novel therapeutic materials for challenging diseases. In the development of RNAi-based therapies, nanoscale particles, with a varying diameter along with facile modification methods that can mediate effective RNAi with targeting potential, are gaining wide interest. The nanotechnology itself has tremendous potential in the field of healthcare, especially for the development of better pharmaceuticals. Nano-enabled delivery has shown great suc

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10

Jasinski, Daniel, Farzin Haque, Daniel W. Binzel, and Peixuan Guo. "Advancement of the Emerging Field of RNA Nanotechnology." ACS Nano 11, no. 2 (2017): 1142–64. http://dx.doi.org/10.1021/acsnano.6b05737.

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11

Biesiada, Marcin, Katarzyna Pachulska-Wieczorek, Ryszard W. Adamiak, and Katarzyna J. Purzycka. "RNAComposer and RNA 3D structure prediction for nanotechnology." Methods 103 (July 2016): 120–27. http://dx.doi.org/10.1016/j.ymeth.2016.03.010.

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12

Guo, Peixuan. "RNA Nanotechnology: Methods for synthesis, conjugation, assembly and application of RNA nanoparticles." Methods 54, no. 2 (2011): 201–3. http://dx.doi.org/10.1016/j.ymeth.2011.06.001.

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13

Qiu, Meikang, Emil Khisamutdinov, Zhengyi Zhao, et al. "RNA nanotechnology for computer design and in vivo computation." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 371, no. 2000 (2013): 20120310. http://dx.doi.org/10.1098/rsta.2012.0310.

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Molecular-scale computing has been explored since 1989 owing to the foreseeable limitation of Moore's law for silicon-based computation devices. With the potential of massive parallelism, low energy consumption and capability of working in vivo , molecular-scale computing promises a new computational paradigm. Inspired by the concepts from the electronic computer, DNA computing has realized basic Boolean functions and has progressed into multi-layered circuits. Recently, RNA nanotechnology has emerged as an alternative approach. Owing to the newly discovered thermodynamic stability of a specia

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14

Dabkowska, Aleksandra P., Agnes Michanek, Luc Jaeger, et al. "Assembly of RNA nanostructures on supported lipid bilayers." Nanoscale 7, no. 2 (2015): 583–96. http://dx.doi.org/10.1039/c4nr05968a.

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15

Xu. "Clay Nanoparticles Facilitate Delivery of Antiviral RNA for Crop Protection." Proceedings 36, no. 1 (2019): 9. http://dx.doi.org/10.3390/proceedings2019036009.

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16

Haque, Farzin, Fengmei Pi, Zhengyi Zhao, et al. "RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications." Wiley Interdisciplinary Reviews: RNA 9, no. 1 (2017): e1452. http://dx.doi.org/10.1002/wrna.1452.

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17

Yourston, Liam, Lewis Rolband, Caroline West, Alexander Lushnikov, Kirill A. Afonin, and Alexey V. Krasnoslobodtsev. "Tuning properties of silver nanoclusters with RNA nanoring assemblies." Nanoscale 12, no. 30 (2020): 16189–200. http://dx.doi.org/10.1039/d0nr03589k.

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Combining atomically resolved DNA-templated silver nanoclusters (AgNCs) with nucleic acid nanotechnology opens new exciting possibilities for engineering bioinorganic nanomaterials with uniquely tunable properties.

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18

Shukla, Girish C., Farzin Haque, Yitzhak Tor, et al. "A Boost for the Emerging Field of RNA Nanotechnology." ACS Nano 5, no. 5 (2011): 3405–18. http://dx.doi.org/10.1021/nn200989r.

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19

Sulc, Petr, Flavio Romano, Thomas Ouldridge, Jonathan Doye, and Ard Louis. "Coarse-Grained Modeling of RNA for Biology and Nanotechnology." Biophysical Journal 112, no. 3 (2017): 369a. http://dx.doi.org/10.1016/j.bpj.2016.11.2004.

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20

Komura, Fusae, Kana Okuzumi, Yuki Takahashi, Yoshinobu Takakura, and Makiya Nishikawa. "Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation." Molecules 25, no. 3 (2020): 728. http://dx.doi.org/10.3390/molecules25030728.

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Guanosine- and uridine-rich single-stranded RNA (GU-rich RNA) is an agonist of Toll-like receptor (TLR) 7 and TLR8 and induces strong immune responses. A nanostructured GU-rich RNA/DNA assembly prepared using DNA nanotechnology can be used as an adjuvant capable of improving the biological stability of RNA and promoting efficient RNA delivery to target immune cells. To achieve a sustained supply of GU-rich RNA to immune cells, we developed a GU-rich RNA/DNA hydrogel (RDgel) using nanostructured GU-rich RNA/DNA assembly, from which GU-rich RNA can be released in a sustained manner. A hexapod-li

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21

Mohebbi, Sohameh, Nahid Bakhtiari, Fahimeh Charbgoo, and Zeinab Shirvani-Farsani. "RNA nanotechnology breakthrough for targeted release of RNA-based drugs using cell-based aptamers." MEDICAL SCIENCES JOURNAL 29, no. 4 (2019): 275–83. http://dx.doi.org/10.29252/iau.29.4.275.

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22

Moumaris, Mohamed, Jean-Michel Bretagne, and Nisen Abuaf. "Nanomedical Devices and Cancer Theranostics." Open Nanomedicine and Nanotechnology Journal 6, no. 1 (2020): 1–11. http://dx.doi.org/10.2174/2666150002006010001.

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The current therapies against cancer showed limited success. Nanotechnology is a promising strategy for cancer tracking, diagnosis, and therapy. The hybrid nanotechnology assembled several materials in a multimodal system to develop multifunctional approaches to cancer treatment. The quantum dot and polymer are some of these hybrid nanoparticle platforms. The quantum dot hybrid system possesses photonic and magnetic properties, allowing photothermal therapy and live multimodal imaging of cancer. These quantum dots were used to convey medicines to cancer cells. Hybrid polymer nanoparticles were

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23

Shaw, Andrew M., Christopher Hyde, Blair Merrick, et al. "Real-world evaluation of a novel technology for quantitative simultaneous antibody detection against multiple SARS-CoV-2 antigens in a cohort of patients presenting with COVID-19 syndrome." Analyst 145, no. 16 (2020): 5638–46. http://dx.doi.org/10.1039/d0an01066a.

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An evaluation of a rapid portable gold-nanotechnology measuring SARS-CoV-2 IgM, IgA and IgG antibody response to spike 1 (S1), spike 2 (S) and nucleocapsid (N) antigens using serum from 74 RNA(+) patients and RNA(+) 47 control patients.

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24

Leontis, Neocles, Blake Sweeney, Farzin Haque, and Peixuan Guo. "Conference Scene: Advances in RNA nanotechnology promise to transform medicine." Nanomedicine 8, no. 7 (2013): 1051–54. http://dx.doi.org/10.2217/nnm.13.105.

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25

Hochrein, Lisa M., Tianjia J. Ge, Maayan Schwarzkopf, and Niles A. Pierce. "Signal Transduction in Human Cell Lysate via Dynamic RNA Nanotechnology." ACS Synthetic Biology 7, no. 12 (2018): 2796–802. http://dx.doi.org/10.1021/acssynbio.8b00424.

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26

Piao, Xijun, Hongran Yin, Sijin Guo, Hongzhi Wang, and Peixuan Guo. "RNA Nanotechnology to Solubilize Hydrophobic Antitumor Drug for Targeted Delivery." Advanced Science 6, no. 22 (2019): 1900951. http://dx.doi.org/10.1002/advs.201900951.

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27

Chan, Ki, and Tzi Bun Ng. "In-vitro nanodiagnostic platform through nanoparticles and DNA-RNA nanotechnology." Applied Microbiology and Biotechnology 99, no. 8 (2015): 3359–74. http://dx.doi.org/10.1007/s00253-015-6506-4.

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28

Chaturvedi, Vivek K., Anshuman Singh, Vinay K. Singh, and Mohan P. Singh. "Cancer Nanotechnology: A New Revolution for Cancer Diagnosis and Therapy." Current Drug Metabolism 20, no. 6 (2019): 416–29. http://dx.doi.org/10.2174/1389200219666180918111528.

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Background:Nanotechnology is gaining significant attention worldwide for cancer treatment. Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a vital component of a customized way to deal with the malignancy. Nanoparticles are being used as Nanomedicine which participates in diagnosis and treatment of various diseases including cancer. The unique characteristic of Nanomedicine i.e. their high surface to volume ratio enables them to tie, absorb, and convey small biomolecule like DNA, RNA, drugs, proteins, and other molecules to targeted site and thus enhance

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29

Green, Alexander A. "Synthetic bionanotechnology: synthetic biology finds a toehold in nanotechnology." Emerging Topics in Life Sciences 3, no. 5 (2019): 507–16. http://dx.doi.org/10.1042/etls20190100.

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Enabled by its central role in the molecular networks that govern cell function, RNA has been widely used for constructing components used in biological circuits for synthetic biology. Nucleic acid nanotechnology, which exploits predictable nucleic acid interactions to implement programmable molecular systems, has seen remarkable advances in in vitro nanoscale self-assembly and molecular computation, enabling the production of complex nanostructures and DNA-based neural networks. Living cells genetically engineered to execute nucleic acid nanotechnology programs thus have outstanding potential

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30

Millagaha Gedara, Nuwan Indika, Xuan Xu, Robert DeLong, Santosh Aryal, and Majid Jaberi-Douraki. "Global Trends in Cancer Nanotechnology: A Qualitative Scientific Mapping Using Content-Based and Bibliometric Features for Machine Learning Text Classification." Cancers 13, no. 17 (2021): 4417. http://dx.doi.org/10.3390/cancers13174417.

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This study presents a new way to investigate comprehensive trends in cancer nanotechnology research in different countries, institutions, and journals providing critical insights to prevention, diagnosis, and therapy. This paper applied the qualitative method of bibliometric analysis on cancer nanotechnology using the PubMed database during the years 2000–2021. Inspired by hybrid medical models and content-based and bibliometric features for machine learning models, our results show cancer nanotechnology studies have expanded exponentially since 2010. The highest production of articles in canc

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31

Worrall, Elizabeth, Aflaq Hamid, Karishma Mody, Neena Mitter, and Hanu Pappu. "Nanotechnology for Plant Disease Management." Agronomy 8, no. 12 (2018): 285. http://dx.doi.org/10.3390/agronomy8120285.

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Each year, 20%–40% of crops are lost due to plant pests and pathogens. Existing plant disease management relies predominantly on toxic pesticides that are potentially harmful to humans and the environment. Nanotechnology can offer advantages to pesticides, like reducing toxicity, improving the shelf-life, and increasing the solubility of poorly water-soluble pesticides, all of which could have positive environmental impacts. This review explores the two directions in which nanoparticles can be utilized for plant disease management: either as nanoparticles alone, acting as protectants; or as na

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32

Fujimoto, Kenzo, Hideaki Yoshino, Tomoko Ohtake, Yoshinaga Yoshimura, and Isao Saito. "Development of Photochemical DNA/RNA Manipulation Toward Its Application for Nanotechnology." Transactions of the Materials Research Society of Japan 35, no. 1 (2010): 85–89. http://dx.doi.org/10.14723/tmrsj.35.85.

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33

Guo, Peixuan, Farzin Haque, Brent Hallahan, Randall Reif, and Hui Li. "Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology." Nucleic Acid Therapeutics 22, no. 4 (2012): 226–45. http://dx.doi.org/10.1089/nat.2012.0350.

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34

Badelt, Stefan, Christoph Flamm, and Ivo L. Hofacker. "Computational Design of a Circular RNA with Prionlike Behavior." Artificial Life 22, no. 2 (2016): 172–84. http://dx.doi.org/10.1162/artl_a_00197.

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RNA molecules engineered to fold into predefined conformations have enabled the design of a multitude of functional RNA devices in the field of synthetic biology and nanotechnology. More complex designs require efficient computational methods, which need to consider not only equilibrium thermodynamics but also the kinetics of structure formation. Here we present a novel type of RNA design that mimics the behavior of prions, that is, sequences capable of interaction-triggered autocatalytic replication of conformations. Our design was computed with the ViennaRNA package and is based on circular

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35

Han, Dongran, Xiaodong Qi, Cameron Myhrvold, et al. "Single-stranded DNA and RNA origami." Science 358, no. 6369 (2017): eaao2648. http://dx.doi.org/10.1126/science.aao2648.

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Self-folding of an information-carrying polymer into a defined structure is foundational to biology and offers attractive potential as a synthetic strategy. Although multicomponent self-assembly has produced complex synthetic nanostructures, unimolecular folding has seen limited progress. We describe a framework to design and synthesize a single DNA or RNA strand to self-fold into a complex yet unknotted structure that approximates an arbitrary user-prescribed shape. We experimentally construct diverse multikilobase single-stranded structures, including a ~10,000-nucleotide (nt) DNA structure

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36

Guo, Peixuan. "A new generation of drugs from the emerging field of RNA nanotechnology." Nanomedicine: Nanotechnology, Biology and Medicine 14, no. 5 (2018): 1758. http://dx.doi.org/10.1016/j.nano.2017.11.062.

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37

Guo, Peixuan. "RNA Nanotechnology: Engineering, Assembly and Applications in Detection, Gene Delivery and Therapy." Journal of Nanoscience and Nanotechnology 5, no. 12 (2005): 1964–82. http://dx.doi.org/10.1166/jnn.2005.446.

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38

Rinoldi, Chiara, Seyed Shahrooz Zargarian, Pawel Nakielski, et al. "Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines." Small Methods 5, no. 9 (2021): 2100402. http://dx.doi.org/10.1002/smtd.202100402.

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39

Tram, Kha, Pushpinder Kanda, and Yingfu Li. "Lighting Up RNA-Cleaving DNAzymes for Biosensing." Journal of Nucleic Acids 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/958683.

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The development of thein vitroselection technique has allowed the isolation of functional nucleic acids, including catalytic DNA molecules (DNAzymes), from random-sequence pools. The first-ever catalytic DNA obtained by this technique in 1994 is a DNAzyme that cleaves RNA. Since then, many other RNase-like DNAzymes have been reported from multiplein vitroselection studies. The discovery of various RNase DNAzymes has in turn stimulated the exploration of these enzymatic species for innovative applications in many different areas of research, including therapeutics, biosensing, and DNA nanotechn

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40

Cox, A. J., H. N. Bengtson, K. H. Rohde, and D. M. Kolpashchikov. "DNA nanotechnology for nucleic acid analysis: multifunctional molecular DNA machine for RNA detection." Chemical Communications 52, no. 99 (2016): 14318–21. http://dx.doi.org/10.1039/c6cc06889h.

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41

Malik, Shipra, Brenda Asmara, Zoe Moscato, Jatinder Kaur Mukker, and Raman Bahal. "Advances in Nanoparticle-based Delivery of Next Generation Peptide Nucleic Acids." Current Pharmaceutical Design 24, no. 43 (2019): 5164–74. http://dx.doi.org/10.2174/1381612825666190117164901.

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Background: Peptide nucleic acids (PNAs) belong to the next generation of synthetic nucleic acid analogues. Their high binding affinity and specificity towards the target DNA or RNA make them the reagent of choice for gene therapy-based applications. Objective: To review important gene therapy based applications of regular and chemically modified peptide nucleic acids in combination with nanotechnology. Method: Selective research of the literature. Results: Poor intracellular delivery of PNAs has been a significant challenge. Among several delivery strategies explored till date, nanotechnology

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42

Zhang, JingJing. "RNA-Cleaving DNAzymes: Old Catalysts with New Tricks for Intracellular and In Vivo Applications." Catalysts 8, no. 11 (2018): 550. http://dx.doi.org/10.3390/catal8110550.

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DNAzymes are catalytically active DNA molecules that are normally isolated through in vitro selection methods, among which RNA-cleaving DNAzymes that catalyze the cleavage of a single RNA linkage embedded within a DNA strand are the most studied group of this DNA enzyme family. Recent advances in DNA nanotechnology and engineering have generated many RNA-cleaving DNAzymes with unique recognition and catalytic properties. Over the past decade, numerous RNA-cleaving, DNAzymes-based functional probes have been introduced into many research areas, such as in vitro diagnostics, intracellular imagin

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43

Shu, Dan, Wulf-Dieter Moll, Zhaoxiang Deng, Chengde Mao, and Peixuan Guo. "Bottom-up Assembly of RNA Arrays and Superstructures as Potential Parts in Nanotechnology." Nano Letters 4, no. 9 (2004): 1717–23. http://dx.doi.org/10.1021/nl0494497.

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44

Lee, Jong-Min, Tae-Jong Yoon, and Young-Seok Cho. "Recent Developments in Nanoparticle-Based siRNA Delivery for Cancer Therapy." BioMed Research International 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/782041.

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RNA interference (RNAi) is a gene regulation mechanism initiated by RNA molecules that enables sequence-specific gene silencing by promoting degradation of specific mRNAs. Molecular therapy using small interfering RNA (siRNA) has shown great therapeutic potential for diseases caused by abnormal gene overexpression or mutation. The major challenges to application of siRNA therapeutics include the stability and effective delivery of siRNAin vivo. Important progress in nanotechnology has led to the development of efficient siRNA delivery systems. In this review, the authors discuss recent advance

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45

Graczyk, Anna, Roza Pawlowska, Dominika Jedrzejczyk, and Arkadiusz Chworos. "Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery." Molecules 25, no. 1 (2020): 204. http://dx.doi.org/10.3390/molecules25010204.

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Development of nanotechnology has become prominent in many fields, such as medicine, electronics, production of materials, and modern drugs. Nanomaterials and nanoparticles have gained recognition owing to the unique biochemical and physical properties. Considering cellular application, it is speculated that nanoparticles can transfer through cell membranes following different routes exclusively owing to their size (up to 100 nm) and surface functionalities. Nanoparticles have capacity to enter cells by themselves but also to carry other molecules through the lipid bilayer. This quality has be

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46

Bui, My N., M. Brittany Johnson, Mathias Viard, et al. "Versatile RNA tetra-U helix linking motif as a toolkit for nucleic acid nanotechnology." Nanomedicine: Nanotechnology, Biology and Medicine 13, no. 3 (2017): 1137–46. http://dx.doi.org/10.1016/j.nano.2016.12.018.

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47

Chandler, Morgan, Tatiana Lyalina, Justin Halman, et al. "Broccoli Fluorets: Split Aptamers as a User-Friendly Fluorescent Toolkit for Dynamic RNA Nanotechnology." Molecules 23, no. 12 (2018): 3178. http://dx.doi.org/10.3390/molecules23123178.

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RNA aptamers selected to bind fluorophores and activate their fluorescence offer a simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive until the halves are brought within close proximity can become useful for visualizing the dynamic actions of RNA assemblies and their interactions in real time with low background noise and eliminated necessity for covalently attached dyes. Here, we design and test several sets of F30 Broccoli aptamer splits, that we call fluorets, to compare their relative fluorescence and physicochemical stabilities. We show that the sp

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48

Binzel, Daniel W., Yi Shu, Hui Li, et al. "Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology." Molecular Therapy 24, no. 7 (2016): 1267–77. http://dx.doi.org/10.1038/mt.2016.85.

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49

Li, Junwei, Dandan Yuan, Xiangjiang Zheng, Xinyue Zhang, Xuemei Li, and Shusheng Zhang. "A triple-combination nanotechnology platform based on multifunctional RNA hydrogel for lung cancer therapy." Science China Chemistry 63, no. 4 (2020): 546–53. http://dx.doi.org/10.1007/s11426-019-9673-4.

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50

O’Hara, Jack, Dylan Marashi, Sean Morton, Luc Jaeger, and Wade Grabow. "Optimization of the Split-Spinach Aptamer for Monitoring Nanoparticle Assembly Involving Multiple Contiguous RNAs." Nanomaterials 9, no. 3 (2019): 378. http://dx.doi.org/10.3390/nano9030378.

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The fact that structural RNA motifs can direct RNAs to fold and self-assemble into predictable pre-defined structures is an attractive quality and driving force for RNA’s use in nanotechnology. RNA’s recognized diversity concerning cellular and synthetically selected functionalities, however, help explain why it continues to draw attention for new nano-applications. Herein, we report the modification of a bifurcated reporter system based on the previously documented Spinach aptamer/DFHBI fluorophore pair that affords the ability to confirm the assembly of contiguous RNA strands within the cont

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