Academic literature on the topic 'RNA ; Proteins ; DNA replication'

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Journal articles on the topic "RNA ; Proteins ; DNA replication"

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ZDRAVKOVIĆ, S., M. V. SATARIĆ, and D. VUKOVIĆ. "MODULATION AND DEMODULATION IN DNA MOLECULE." Modern Physics Letters B 20, no. 11 (2006): 607–15. http://dx.doi.org/10.1142/s0217984906010706.

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In this paper, we consider the transformation of a breather type soliton in DNA into its demodulated version due to the strong impact of proteins associated with some sequences of DNA chain. These proteins are, for example, RNA polymerase responsible for the formation of m-RNA or initiation protein complex indispensable for chromosome replication.
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Wiedmer, Andreas, Pu Wang, Jing Zhou, et al. "Epstein-Barr Virus Immediate-Early Protein Zta Co-Opts Mitochondrial Single-Stranded DNA Binding Protein To Promote Viral and Inhibit Mitochondrial DNA Replication." Journal of Virology 82, no. 9 (2008): 4647–55. http://dx.doi.org/10.1128/jvi.02198-07.

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ABSTRACT Disruption of cellular metabolic processes and usurpation of host proteins are hallmarks of herpesvirus lytic infection. Epstein-Barr virus (EBV) lytic replication is initiated by the immediate-early protein Zta. Zta is a multifunctional DNA binding protein that stimulates viral gene transcription, nucleates a replication complex at the viral origin of lytic replication, and inhibits cell cycle proliferation. To better understand these functions and identify cellular collaborators of Zta, we purified an epitope-tagged version of Zta in cells capable of supporting lytic replication. FL
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Ohba, R., K. Matsumoto, and Y. Ishimi. "Induction of DNA replication by transcription in the region upstream of the human c-myc gene in a model replication system." Molecular and Cellular Biology 16, no. 10 (1996): 5754–63. http://dx.doi.org/10.1128/mcb.16.10.5754.

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An important relationship between transcription and initiation of DNA replication in both eukaryotes and prokaryotes has been suggested. In an attempt to understand the molecular mechanism of this interaction, we examined whether transcription can induce DNA replication in vitro by constructing a system in which both replication and transcription were combined. Relaxed circular DNA possessing a replication initiation zone located upstream of the human c-myc gene and a T7 promoter near the P1 promoter of the gene was replicated in the presence of T7 RNA polymerase. In our model system, replicat
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Barton, Deborah A., Elke F. Roovers, Quentin Gouil, et al. "Live Cell Imaging Reveals the Relocation of dsRNA Binding Proteins Upon Viral Infection." Molecular Plant-Microbe Interactions® 30, no. 6 (2017): 435–43. http://dx.doi.org/10.1094/mpmi-02-17-0035-r.

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Viral infection triggers a range of plant responses such as the activation of the RNA interference (RNAi) pathway. The double-stranded RNA binding (DRB) proteins DRB3 and DRB4 are part of this pathway and aid in defending against DNA and RNA viruses, respectively. Using live cell imaging, we show that DRB2, DRB3, and DRB5 relocate from their uniform cytoplasmic distribution to concentrated accumulation in nascent viral replication complexes (VRC) that develop following cell invasion by viral RNA. Inactivation of the DRB3 gene in Arabidopsis by T-DNA insertion rendered these plants less able to
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Guogas, Laura, James Hogle, and Lee Gehrke. "Origins of Life and the RNA World: Evolution of RNA-Replicase Recognition." Symposium - International Astronomical Union 213 (2004): 321–24. http://dx.doi.org/10.1017/s0074180900193489.

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Central to understanding the origin of life is the elucidation of the first replication mechanism. The RNA World hypothesis suggests that the first self-replicating molecules were RNAs and that DNA later superceded RNA as the genetic material. RNA viruses were not subjected to the same evolutionary pressures as cellular organisms; consequently, they likely possess remnants of earlier replication strategies. Our laboratory investigates how members of the RNA virus family Bromoviridae can have structurally distinct 3' end tags yet are specifically recognized by conserved replication enzymes. Thi
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Kavanaugh, Gina, Runxiang Zhao, Yan Guo, et al. "Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing." Molecular and Cellular Biology 35, no. 17 (2015): 2979–90. http://dx.doi.org/10.1128/mcb.01276-14.

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Accurate replication of DNA is imperative for the maintenance of genomic integrity. We identified Enhancer of Rudimentary Homolog (ERH) using a whole-genome RNA interference (RNAi) screen to discover novel proteins that function in the replication stress response. Here we report that ERH is important for DNA replication and recovery from replication stress. ATR pathway activity is diminished in ERH-deficient cells. The reduction in ATR signaling corresponds to a decrease in the expression of multiple ATR pathway genes, including ATR itself. ERH interacts with multiple RNA processing complexes,
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Rogan, Peter K., Eliseos J. Mucaki, and Ben C. Shirley. "A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections." F1000Research 9 (August 7, 2020): 943. http://dx.doi.org/10.12688/f1000research.25390.1.

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Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) from nuclear RNA bound to replicating viral sequences. Methods: Information theory-based analysis of interactions between RBPs and individual sequences in the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), Influenza A (H3N1), HIV-1, and Dengue genomes identifies strong RBP binding sites in these viral genomes. Replication and expressio
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Rogan, Peter K., Eliseos J. Mucaki, and Ben C. Shirley. "A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections." F1000Research 9 (January 6, 2021): 943. http://dx.doi.org/10.12688/f1000research.25390.2.

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Background: Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding proteins (RBPs) from nuclear RNA bound to replicating viral sequences. Methods: Information theory-based analysis of interactions between RBPs and individual sequences in the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), Influenza A (H3N2), HIV-1, and Dengue genomes identifies strong RBP binding sites in these viral genomes. Replication and expressio
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Dudas, Kathleen C., and Kenneth N. Kreuzer. "UvsW Protein Regulates Bacteriophage T4 Origin-Dependent Replication by Unwinding R-Loops." Molecular and Cellular Biology 21, no. 8 (2001): 2706–15. http://dx.doi.org/10.1128/mcb.21.8.2706-2715.2001.

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ABSTRACT The UvsW protein of bacteriophage T4 is involved in many aspects of phage DNA metabolism, including repair, recombination, and recombination-dependent replication. UvsW has also been implicated in the repression of origin-dependent replication at late times of infection, when UvsW is normally synthesized. Two well-characterized T4 origins, ori(uvsY) andori(34), are believed to initiate replication through an R-loop mechanism. Here we provide both in vivo and in vitro evidence that UvsW is an RNA-DNA helicase that catalyzes the dissociation of RNA from origin R-loops. Two-dimensional g
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Johnson, Kyle L., and L. Andrew Ball. "Induction and Maintenance of Autonomous Flock House Virus RNA1 Replication." Journal of Virology 73, no. 10 (1999): 7933–42. http://dx.doi.org/10.1128/jvi.73.10.7933-7942.1999.

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The nodavirus flock house virus (FHV) has a bipartite, positive-sense, RNA genome that encodes the catalytic subunit of the RNA replicase and the viral capsid protein precursor on separate genomic segments (RNA1 and RNA2, respectively). RNA1 can replicate autonomously when transfected into permissive cells, allowing study of the kinetics of RNA1 replication in the absence of either RNA2 or capsid proteins. However, RNA1 replication ceases ca. 3 days after transfection despite the presence of replication-competent RNA. We examined this inhibition by inducing the expression of RNA1 in cells from
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Dissertations / Theses on the topic "RNA ; Proteins ; DNA replication"

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Langley, Alexander Richard. "Interactions between non-coding Y RNAs and proteins in the context of the initiation of human chromosomal DNA replication." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609101.

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Hillukkala, T. (Tomi). "Roles of DNA polymerase epsilon and TopBP1 in DNA replication and damage response." Doctoral thesis, University of Oulu, 2006. http://urn.fi/urn:isbn:9514282922.

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Abstract During DNA replication cells accurately copy their DNA to transfer the genetic information to daughter cells. DNA polymerases synthesise the new DNA strand using the old strand as a template. Other functions of DNA polymerases are recombination linked and DNA iamage repair linked DNA synthesis, regulation of replication complex formation and regulation of transcription – a process in which the genetic information is transformed into an RNA sequence needed to guide protein synthesis. In this study, the TopBP1 protein was shown to associate with DNA polymerase epsilon. TopBP1 contains
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Tsao, Theresa Tsun-Hui. "Towards the development of transgenic banana bunchy top virus (BBTV)-resistant banana plants : interference with replication." Queensland University of Technology, 2008. http://eprints.qut.edu.au/17031/.

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Banana bunchy top virus (BBTV) causes one of the most devastating diseases of banana. Transgenic virus resistance is now considered one of the most promising strategies to control BBTV. Pathogen-derived resistance (PDR) strategies have been applied successfully to generate plants that are resistant to numerous different viruses, primarily against those viruses with RNA genomes. BBTV is a circular, single-stranded (css) DNA virus of the family Nanoviridae, which is closely related to the family Geminiviridae. Although there are some successful examples of PDR against geminiviruses, PDR against
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Tokonzaba, Etienne. "Molecular mechanism of SV40 large tumor antigen helicase /." Connect to abstract via ProQuest. Full text is not available online, 2007.

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Thesis (Ph.D. in Pharmacology) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 82-92; 128-134). Online version available via ProQuest Digital Dissertations.
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Leriche, Mélissa. "Mise en évidence d’une interaction entre la protéine 53BP1 et les fragments d’Okazaki." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASS065.

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Le maintien de l’intégrité du génome est un processus crucial à la vie cellulaire. Ce n’est que récemment que les protéines de liaison à l’ARN (« RNA-binding protein » ou RBP) ont été montré être impliquées dans ce processus. En présence d’ADN endommagé, les RBP régulent l’expression des gènes de réponse aux dommages de l’ADN et contrôlent le destin cellulaire. Elles jouent également un rôle plus direct dans la prévention et la réparation des dommages de l’ADN. De plus, des ARN sont présents aux sites de dommages de l’ADN et participent au maintien de l’intégrité du génome. Ainsi, le laboratoi
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Pageau, Gayle Jeannette. "Maintenance of Constitutive and Inactive X Heterochromatin in Cancer and a Link to BRCA1: A Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/331.

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The development of cancer is a multi-step process which involves a series of events, including activation of oncogenes and loss of tumor suppressor function, leading to cell immortalization and misregulated proliferation. In the last few years, the importance of epigenetic defects in cancer development has become increasingly recognized. While most epigenetic studies focus on silencing of tumor suppressors, this thesis addresses defects in the maintenance of silenced heterochromatin in cancer, particularly breast cancer. Breast cancer is a leading cause of cancer in women and many familial
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Pageau, Gayle Jeannette. "Maintenance of Constitutive and Inactive X Heterochromatin in Cancer and a Link to BRCA1: A Dissertation." eScholarship@UMMS, 2006. http://escholarship.umassmed.edu/gsbs_diss/331.

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The development of cancer is a multi-step process which involves a series of events, including activation of oncogenes and loss of tumor suppressor function, leading to cell immortalization and misregulated proliferation. In the last few years, the importance of epigenetic defects in cancer development has become increasingly recognized. While most epigenetic studies focus on silencing of tumor suppressors, this thesis addresses defects in the maintenance of silenced heterochromatin in cancer, particularly breast cancer. Breast cancer is a leading cause of cancer in women and many familial
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Bailey, Daniel John. "Cellular proteins in picornavirus replication." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298484.

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Komori, Hirofumi. "Structural studies on DNA-binding proteins : DNA replication initiator and DNA photolyase." 京都大学 (Kyoto University), 2002. http://hdl.handle.net/2433/150005.

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Antonopoulos, Ioanna H. "CHARACTERIZING RNA TRANSCRIPTION AND DNA REPLICATION VIA RAMAN CRYSTALLOGRAPHY." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1428076280.

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Books on the topic "RNA ; Proteins ; DNA replication"

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The molecules of life: DNA, RNA, and proteins. Facts On File, 2009.

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NATO Advanced Study Institute Summer School on the Molecular Basis of Viral Replication (1986 Maratea, Italy). The molecular basis of viral replication. Plenum Press, 1987.

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UCLA, Symposium on Molecular Mechanisms in DNA Replication and Recombination (1989 Keystone Colo ). Molecular mechanisms in DNA replication and recombination: Proceedings of a UCLA Symposium held at Keystone, Colorado, March 27-April 3, 1989. Wiely-Liss, 1990.

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Travers, A. A. DNA-protein interactions. Chapman & Hall, 1993.

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Gaston, Kevin. Small DNA tumour viruses. Caister Academic Press, 2012.

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1948-, Tymoczko John L., and Stryer Lubert, eds. Biochemistry. 6th ed. W. H. Freeman, 2006.

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Krebs, Jocelyn E. Lewin's genes XI. Jones & Bartlett Learning, 2013.

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C, Richardson Charles, and Lehman I. Robert, eds. Molecular mechanisms in DNA replication and recombination: Proceedings of a UCLA Symposium held at Keystone, Colorado, March 27-April 3, 1989. Wiley-Liss, 1990.

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Lee, Hoyun. Proliferating cell nuclear antigen (PCNA). Research Signpost, 2006.

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Artsimovitch, Irina, and Thomas J. Santangelo. Bacterial transcriptional control: Methods and protocols. Humana Press, 2015.

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Book chapters on the topic "RNA ; Proteins ; DNA replication"

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Hübscher, Ulrich. "DNA Replication Fork Proteins." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-815-7_2.

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Sinkovics, Joseph G. "YY Proteins." In RNA/DNA and Cancer. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22279-0_8.

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Sinkovics, Joseph G. "Viral and Cellular Proteins Interact." In RNA/DNA and Cancer. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22279-0_16.

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Blossey, Ralf. "Biomolecular Structure: DNA, RNA, Proteins." In Computational Biology. CRC Press, 2019. http://dx.doi.org/10.1201/9780429503672-2.

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Frey, A., T. Chittenden, and A. J. Levine. "Epstein-Barr Virus DNA Replication." In Transforming Proteins of DNA Tumor Viruses. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74578-2_28.

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Collins, Kathleen L., Lome F. Erdile, Sandra K. Randall, et al. "SV40 DNA Replication with Purified Proteins: Functional Interactions Among the Initiation Proteins." In DNA Replication: The Regulatory Mechanisms. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-76988-7_33.

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Hübscher, U., G. Cullmann, P. Thömmes, et al. "Mammalian DNA Helicases, DNA Polymerases and DNA Polymerase Auxiliary Proteins." In DNA Replication and the Cell Cycle. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77040-1_6.

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Tye, B. K., V. Chang, C. Christ, et al. "Proteins Involved in ARS Function in Yeast." In DNA Replication: The Regulatory Mechanisms. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-76988-7_19.

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Hass, Cathy S., Ran Chen, and Marc S. Wold. "Detection of Posttranslational Modifications of Replication Protein A." In Single-Stranded DNA Binding Proteins. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-032-8_15.

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Theis, James F., and Carol S. Newlon. "Screens for Proteins Binding to the ARS Consensus Sequence." In DNA Replication: The Regulatory Mechanisms. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-76988-7_16.

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Conference papers on the topic "RNA ; Proteins ; DNA replication"

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Young, Paul W. "Student-produced video of role-plays on topics in cell biology and biochemistry: A novel undergraduate group work exercise." In Learning Connections 2019: Spaces, People, Practice. University College Cork||National Forum for the Enhancement of Teaching and Learning in Higher Education, 2019. http://dx.doi.org/10.33178/lc2019.15.

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Group work or cooperative learning is a form of active learning that has potential benefits that extend beyond just being an alternative or improved way of learning course material. For example, Shimazoe and Aldrich (2010) identified six proposed benefits of active learning to students, namely (1) promoting deep learning, (2) helping students earn higher grades, (3) teaching social skills &amp; civic values, (4) teaching higher order thinking skills, (5) promoting personal growth and (6) developing positive attitudes toward autonomous learning. There is evidence for the effectiveness of role-p
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Yang, Runtao, Chengjin Zhang, Rui Gao, and Lina Zhang. "A machine learning approach to identify DNA replication proteins from sequence-derived features." In 2015 IEEE 28th Canadian Conference on Electrical and Computer Engineering (CCECE). IEEE, 2015. http://dx.doi.org/10.1109/ccece.2015.7129092.

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"PARP1 activation directs RNA binding proteins to DNA damages to form PARG reversible compartments enriched in damaged DNA." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-359.

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Sahin, Ozgur. "High throughput nanomechanical measurements on proteins DNA and RNA with a T-shaped cantilever." In 2009 IEEE/LEOS International Conference on Optical MEMS and Nanophotonics. IEEE, 2009. http://dx.doi.org/10.1109/omems.2009.5338630.

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Lee, C. H., H. Teng, and J. S. Chen. "Atomistic to Continuum Modeling of DNA Molecules." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13157.

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The mechanical properties of DNA has very important biological implication. For example, the bending and twisting rigidities of DNA affect how it wraps around histones to form chromosomes, bends upon interactions with proteins, supercoils during replication process, and packs into the confined space within a virus. Many biologically important processes involving DNA are accompanied by the deformations of double helical structure of DNA.
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Akbar-Khanzadeh, F., M. Jahangir-Blourchian, and M. Valigosky. "17. Ultraviolet Radiation Exposure During Gel Electrophoresis Visualization Used for the Detection of Proteins, DNA and RNA in Research Laboratories." In AIHce 2002. AIHA, 2002. http://dx.doi.org/10.3320/1.2766101.

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Connor, Katherine L., Adrian W. Briggs, Stephen J. Goldfless, et al. "Abstract 1442: Comprehensive TIL profiling by simultaneous DNA barcoding of proteins, RNA and natively paired immune receptors from millions of single cells." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1442.

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Fortin, Sébastien, Hanane Moussa, Mathieu Gagné-Boulet, et al. "Abstract 4487: Design, synthesis, and biological activity of N-phenyl ureidobenzenesulfonates (PUB-SOs) as new and innovative small-molecule drugs inhibiting proteins involved in DNA repair/replication mechanisms." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4487.

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Rajput, B., D. Alaimo, A. M. Asselbergs, and E. Reich. "CONSTRUCTION AND EXPRESSION OF HYBRID PLASMINOGEN ACTIVATOR GENES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644412.

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Hybrid plasminogen activator (PA) genes containing fragments of cDNA encoding the non-catalytic part of tissue-PA and the .catalytic domain of urokinase and vice versa were constructed and expressed in Chinese Hamster ovary (CHO) cells. The hybrid nature of the products in stably transformed cells was analyzed at the level of DNA and RNA using probes derived from different regions of the urokinase and tissue-PA cDNAs and at the protein level by means of polyclonal antibodies raised against tissue-PA and urokinase. The hybrid genes made hybrid RNAs and proteins of the expected sizes. The protei
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Jubery, Talukder Zaki, Anmiv S. Prabhu, Min Jun Kim, and Prashanta Dutta. "Modeling and Simulation of Translocation Phenomenon in a Solid State Nanopore for Nanoparticle Separation." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-38742.

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Solid state nanopore is a potential candidate for separation of nanoparticles or biomolecules such as proteins, DNA, and RNA. However, efficient separation of particles through nanopores is a challenging task as a number of factors such as externally applied voltage, size and charge density of particle, size and charge density of membrane pore, and the concentration of bulk electrolyte influence the translocation behavior of nanoparticles through pores. This paper uses a mathematical model based on Poisson–Nernst–Plank equations along with Navier-Stokes equations to systematically study these
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Reports on the topic "RNA ; Proteins ; DNA replication"

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Jackson, Peter K. DNA Replication Initiator Proteins and Genetic Instability: Creating a Mouse Model for Prostate Cancer. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada392190.

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Hood-DeGrenier, Jennifer. Active Learning Workshops for Teaching Key Topics in Introductory Cell and Molecular Biology: Structure of DNA/RNA, Structure of Proteins, and Cell Division via Mitosis and Meiosis. Genetics Society of America Peer-Reviewed Education Portal (GSA PREP), 2015. http://dx.doi.org/10.1534/gsaprep.2015.004.

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