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Journal articles on the topic 'RNTCP guidelines'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

L., Raghavendra, Subhas Babu P., and Shivakumar K. M. "Assessment of knowledge of intern doctors of a medical college hospital in Karnataka on revised national TB control programme." International Journal of Advances in Medicine 4, no. 4 (2017): 1123. http://dx.doi.org/10.18203/2349-3933.ijam20173244.

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Background: The medical interns usually are the first contact health care providers for patients in teaching hospitals and need to be sensitized towards newer diagnostic and treatment guidelines of various national health programmes. Revised National TB Control Programme is one such health programme which aims to reduce TB burden in our country. The present study was undertaken with an objective to assess knowledge level of medical interns, about recent guidelines of RNTCP pertaining to diagnosis and management of TB, including MDR and XDR-TB.Methods: A cross sectional study was conducted at o

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Date, Kalpana, Neena Nagdeo, and Meenal Kulkarni. "A comparative study of sensitivity of sputum microscopy by direct method versus sodium hypochlorite concentration method at RNTCP Centre." Panacea Journal of Medical Sciences 7, no. 1 (2017): 19–21. https://doi.org/10.18231/2348-7682.2017.0006.

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In revised national tuberculosis control program (RNTCP), microscopic examination of sputum for AFB plays an important role in the initial diagnosis of tuberculosis. Decontamination and liquefaction with by 5% sodium hypochlorite increases sensitivity and safety for handling specimen. In this prospective hospital based cross sectional analytical study, patients of all ages and either sex coming to RNTCP centre were included according to RNTCP criteria. From each patient, two samples of sputum were collected one spot and one morning. One set of smears was prepared by RNTCP guidelines and remain

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Ajith, Anamika, and Dr Rekha Nayaka M.R. "To Assess the Knowledge and Awareness of Interns Regarding the Management of Tuberculosis as per Recent RNTCP (2017-2025) Guidelines – A Cross Sectional Study." International Journal of Innovative Science and Research Technology 5, no. 7 (2020): 1104–11. http://dx.doi.org/10.38124/ijisrt20jul738.

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India has been engaged in Tuberculosis control activities for more than 50 years as India is the highest TB burdened country in the world. One such initiative is Revised National Tuberculosis Control Programme (RNTCP) which has been rechristened as National Tuberculosis Elimination Programme (NTEP). The change in name is in line with the larger goal of eliminating the disease by 2025. Objective: The aim of this cross-sectional study is to assess the knowledge and awareness of interns regarding the management of tuberculosis as per recent RNTCP guidelines. Materials & Methods: A structured

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Sarkar, Tuhin Shubhra, Indranath Ghosh, and Abhijit Mukherjee. "Involvement of the clinical departments of a medical college in a rural area in the Revised National Tuberculosis Control Programme in India." Journal of Comprehensive Health 5, no. 1 (2020): 68–75. http://dx.doi.org/10.53553/jch.v05i01.006.

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Introduction: In addition to their role in the diagnosis and treatment of tuberculosis, medical colleges are involved in imparting knowledge and skills to the future generation of medical doctors. In order that RNTCP runs smoothly, it is important that all clinical departments are involved in RNTCP and manage their TB patients according to their guidelines. Objectives: To assess the attendance of TB cases at the clinical departments of a medical college and the categorizing practices of these departments reflecting their involvement in RNTCP. Materials and methods: The study was conducted at t

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Maheswari, E. Uma, R. M. Bhoopathy, K. Bhanu, and Heber Anandan. "Clinical Spectrum of Central Nervous System Tuberculosis and the Efficacy of Revised National Tuberculosis Control Program in its Management." Journal of Neurosciences in Rural Practice 10, no. 01 (2019): 71–77. http://dx.doi.org/10.4103/jnrp.jnrp_163_18.

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ABSTRACTIntroduction: Tuberculosis (TB) is a major global problem and poses a threat which is of considerable magnitude, with an estimated one-third of the population infected with TB bacillus. Aim: The aim of this study is to study the treatment outcomes in patients with various forms of neurological TB treated with the standardized Revised National TB Control Program (RNTCP), directly observed treatment short-course (DOTS). Materials and Methods: Patients diagnosed to have TBM, tuberculoma with or without spinal arachnoiditis (central nervous system tuberculosis-TB [CNS-TB]) were categorized

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Jayapriya, B., PV Balamurugan, and A. Hareesh. "Awareness about the Notification of Tuberculosis among Private Practitioners in Madurai District: A Cross Sectional Study." International Journal of Pharmaceutical and Clinical Research 15, no. 2 (2023): 780–91. https://doi.org/10.5281/zenodo.12819350.

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<strong>Introduction: </strong>Tuberculosis (TB) notification is defined as the process of reporting diagnosed TB cases to relevant health authorities, whom in turn report them to the World Health Organization (WHO) through National TB Programmes (NTPs). While TB cases detected in the public sector health facilities generally get notified, a large proportion of cases that are detected and treated in the private sector do not get notified. Increasing the awareness about notification of TB will increase the notification by private sector including practitioners, labs and pharmacies. This st

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Thakur, Saroj Kumar, Vishvesh Prakashchandra Bansal, Jyotsna Mishra, M. P. Bansal, Iswari Sapkota, and Tapeshwar Yadav. "Improved Diagnosis of Pulmonary Tuberculosis using Bleach (Sodium hypochlorite) Concentration Technique at Tertiary Care Hospital." Nepal Journal of Health Sciences 1, no. 2 (2021): 15–22. http://dx.doi.org/10.3126/njhs.v1i2.42371.

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Introduction: In the Revised National Tuberculosis Control Program (RNTCP), microscopic examination of sputum for acid-fast bacilli (AFB) is currently the backbone for the diagnosis of pulmonary tuberculosis. Studies have shown liquefaction and concentration of sputum by 5% sodium hypochlorite is useful in providing increased sensitivity and safety for the handling of specimens. Objective: To assess the utility of the 5% Sodium hypochlorite concentration method in increasing the sensitivity of smear microscopy for detection of AFB for diagnosis of pulmonary tuberculosis. Methods: The study inc

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Nautiyal, Ram Gopal, and Rajesh Kumar Singh. "Management of pulmonary tuberculosis in private health sector: is it according to revised national tuberculosis control programme guidelines?" International Journal Of Community Medicine And Public Health 6, no. 2 (2019): 759. http://dx.doi.org/10.18203/2394-6040.ijcmph20190203.

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Background: As private sector is dominant tuberculosis (TB) care provider in India, to realize the vision of TB free India, it is crucial that public and private sector follow uniform standard of TB care. This can be achieved when private health sector adopts TB management methodology of Revised National Tuberculosis Control Programme (RNTCP) of India. The present study was conducted to estimate whether or not TB management practices of allopathic private practitioners (PPs) conform to RNTCP guidelines by assessment of their knowledge and practice about new pulmonary TB (PTB).Methods: A cross-

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Mohindroo, NK, DR Sharma, JS Thakur, Ishan Chauhan, and Shobha Mohindroo. "Primary Nasal Tuberculosis." An International Journal Clinical Rhinology 4, no. 1 (2011): 39–41. http://dx.doi.org/10.5005/jp-journals-10013-1067.

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ABSTRACT Tuberculosis of nose, nasopharynx and paranasal sinus is extremely rare even in countries with a high incidence of pulmonary disease. We present two cases of primary nasal tuberculosis managed in last three years in our department with 2500 to 3000 patient visits per month. One case simulated basal cell carcinoma while other case was an ATT defaulter. Both the cases were managed on RNTCP guidelines. Nasal tuberculosis needs high level of suspicion and is diagnosed with laboratory support.

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P. M., Ramesh, and Saravanan M. "Impact of drug susceptibility on treatment outcome in sputum smear positive pulmonary tuberculosis patients receiving category-II regimen in RNTCP under field conditions in an urban setting." International Journal of Advances in Medicine 5, no. 3 (2018): 561. http://dx.doi.org/10.18203/2349-3933.ijam20181663.

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Background: The study was conducted with the aim to evaluate the pre-treatment drug susceptibility profile and to assess the influence of drug resistance on treatment outcome among patients treated with category- II (cat- II) regimen under programme conditions.Methods: This study was conducted on 58 smear positive patients with history of previous anti-tuberculosis treatment for more than one month, comprising cases of ‘Failure’, ‘Treatment after Default’ (TAD) and ‘Relapse’. They received cat- II regimen in Chennai Corporation, RNTCP (revised National tuberculosis control programme) centers f

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Bheemayya, B., S. Y. Supriya, K. M. Archana, and Patil Rajashree. "Study on Awareness of RNTCP Protocols and Guidelines among Private Practitioners in Urban Davangere Karnataka." Indian Journal of Public Health Research & Development 6, no. 1 (2015): 27. http://dx.doi.org/10.5958/0976-5506.2015.00006.6.

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Rawat, Jagdish, Debasis Biswas, Girish Sindhwani, Vikas Kesharwani, Victor Masih, and Bhupendra Singh Chauhan. "Diagnostic defaulters: an overlooked aspect in the Indian Revised National Tuberculosis Control Program." Journal of Infection in Developing Countries 6, no. 01 (2011): 20–22. http://dx.doi.org/10.3855/jidc.1895.

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Introduction: The Revised National Tuberculosis Control Program (RNTCP) aims to achieve detection of 70% of new smear-positive patients in a community and to cure 85% of such patients. Though an elaborate recording and reporting system is in place to monitor the success of the program, no record of patients who do not complete the diagnostic process is currently maintained. The present study, performed in a tertiary care hospital, attempted to estimate the proportion of this group of patients, who were labeled "diagnostic defaulters."Methodology: This prospective observational study was conduc

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Kumar, Ashok, Jawahar Lal Joshi, Abdurazack Umathoor, Vishal Chopra, Komaldeep Kaur, and Vidhu Mittal. "Prevalence of primary drug resistance to rifampicin and isoniazid in newly diagnosed sputum smear positive pulmonary Tuberculosis." International Journal of Research in Medical Sciences 7, no. 9 (2019): 3532. http://dx.doi.org/10.18203/2320-6012.ijrms20193942.

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Background: To determine the prevalence of primary drug resistance to either rifampicin or isoniazid alone or both in newly diagnosed sputum smear positive pulmonary tuberculosis patients.Method: A prospective study 100 newly diagnosed sputum smear positive pulmonary TB patients was conducted. The patients with an age of ≥15 years and who had either not taken anti TB treatment or who had taken ATT for less than 1 month were enrolled in this study. Two sputum samples (5ml each), including one early morning sample as per the RNTCP guidelines were collected and subjected to line probe assay (LPA)

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Eruva, Vijayalakshmi, Clarence James Samuel, and Shavinder Singh. "Collision of two epidemics: prevalence of diabetes in tuberculosis patients in urban Ludhiana." International Journal Of Community Medicine And Public Health 7, no. 4 (2020): 1342. http://dx.doi.org/10.18203/2394-6040.ijcmph20201044.

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Background: Co-association between tuberculosis (TB) and diabetes has been observed for more than 2000 years. The burden of the both diabetes and tuberculosis is very high in India. Diabetes in TB patient decreases the success of anti-tubercular therapy and overall cure rates, which causes social and economic burden to country. The objective of the study was to find out the prevalence of diabetes mellitus in patients with tuberculosis under RNTCP treatment.Methods: This cross-sectional study was conducted in DOTS centers under Civil Hospital TU of Ludhiana, Punjab. 300 TB cases, above 18 years

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Lodaria, Binal Nitin, Prasad Muley, and Dhrumika Sheth. "Anticoagulation in pulmonary TB induced deep vein thrombosis is it always warranted: a case report." International Journal of Research in Medical Sciences 8, no. 7 (2020): 2678. http://dx.doi.org/10.18203/2320-6012.ijrms20202916.

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India is a densely populated developing country and accounts for one quarter of the total tuberculosis cases reported worldwide. Deep vein thrombosis (DVT) has been associated with 1.5-3.4% cases of tuberculosis. A 14 year female presented with complaints of cough with progressive breathlessness (NYHA Grade III) since 15 days along with easy fatiguability and fever for 3 days. The patient was started on Anti-Tubercular Treatment (ATT) as per RNTCP guidelines after thorough investigations. One week after the patient was started on ATT, the patient developed edema of the right lower limb accompa

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Jha, Rajeev Kumar, Vikram Singh, M. Vijayasimha, and Gimmi Chhetry. "A Comparative Assessment of Petroff’s and N-Acetyl-L-Cysteine- Sodium Hydroxide Method in the Diagnosis of Pulmonary Tuberculosis." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 425–29. http://dx.doi.org/10.22270/jddt.v9i3-s.2976.

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Tuberculosis (TB) stays one of the deadliest communicable disease and responsible for almost two million deaths every year worldwide. The objective of the present study is to compare Petroff’s and N-acetyl-L cysteine- sodium hydroxide methods used for the diagnosis of pulmonary tuberculosis. This present study was conducted in the department of ST John’s Medical college and Hospital, Bangalore, from October 2011 to September 2012. Total 100 sputum specimen was collected from patients under the Revised National Tuberculosis Control Program (RNTCP) Guidelines. These samples were decontaminated w

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Warkari, Prashant D., Mahavir P. Nakel, Swati M. Mahajan, and Sangita A. Adchitre. "Study of treatment outcome of tuberculosis among HIV co-infected patients: a cross sectional study in Aurangabad city, Maharashtra." International Journal Of Community Medicine And Public Health 4, no. 12 (2017): 4466. http://dx.doi.org/10.18203/2394-6040.ijcmph20175163.

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Background: Tuberculosis is the most common presenting illness among people living with HIV, including those who are taking anti-retroviral treatment. There were an estimated 1.2 million HIV positive new TB cases globally in 2014. Around 74% of these infected people live in sub-Saharan Africa. Aim and objectives were to study the treatment outcome of tuberculosis among HIV co-infected patients; to assess the outcome of TB treatment in TB patients with respect to their HIV status and to study the underlying factors influencing the outcome rates. Methods: A descriptive cross-sectional study was

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Sudhir, Kumar. "Exploring Final Year MBBS Students' Knowledge of National Tuberculosis Programs and Antitubercular Medications in a Tertiary Care Hospital." International Journal of Toxicological and Pharmacological Research 13, no. 2 (2023): 113–17. https://doi.org/10.5281/zenodo.11281842.

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<strong>Aim: </strong>The goal of this study is to assess final-year MBBS students’ knowledge of National Tuberculosis Programs and antitubercular drugs at a Tertiary Care Hospital. <strong>Methods: </strong>A cross-sectional study was conducted in a Department of Tb and Chest, Lord Buddha Koshi medical College, Saharsa, Bihar, India in duration of 1 year. 120 final year MBBS students were selected for the research using a simple random sampling technique. A pre-designed survey form was used to collect data, which also included queries about national tuberculosis programme

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A., Mogan K., Richa Kapoor, Shveta Lukhmana, Aakanksha Bharti, and Mohit Goyal. "Screening for tuberculosis among sanitation workers in a tertiary care hospital, Delhi, India: a cross-sectional study." International Journal Of Community Medicine And Public Health 7, no. 12 (2020): 5075. http://dx.doi.org/10.18203/2394-6040.ijcmph20205187.

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Background: The surveillance of TB reduces disease transmission by shortening the duration of infectiousness and this reduces the incidence of TB infection and consequently contributes to reduced incidence of TB disease. The study aimed to screen for tuberculosis among the sanitation workers in a tertiary care hospital and assess the associated factors to provide the burden of tuberculosis among sanitation workers.Methods: The present study was conducted in Safdarjung Hospital, one of the largest Tertiary care hospital in India, located in the Southern part of Delhi. This was a cross-sectional

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Shah, Chirag, Shantanu Jain, and Pathik Patel. "Study of extrapulmonary tuberculosis in tertiary care hospital children with reference to cartridge based nucleic acid amplification test." International Journal of Contemporary Pediatrics 8, no. 12 (2021): 1947. http://dx.doi.org/10.18203/2349-3291.ijcp20214533.

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Background: Tuberculosis is an infectious disease cause by the mycobacterium tuberculosis which typically involve lung but can affect other site called extrapulmonary tuberculosis (EPTB). In EPTB lymph node tuberculosis is most common and most severe is tuberculous meningitis. Cartridge based nucleic acid amplification test (CBNAAT) have high sensitivity and perform both respiratory and non-respiratory specimen. The aim of this retrospective study is to find out the proportion of extra pulmonary tuberculosis in hospitalized patient and determine the association of CBNAAT in diagnosis EPTB and

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Padma, Maneya, Nuthan Kumar, Jyothi Munireddy, Arun Kumar, Pooja Chebbi Gujjal, and S. Chennagiri Premalata. "Tuberculosis Coexistence in Pediatric Hodgkin’s Lymphoma: A Tropical Country Experience." South Asian Journal of Cancer 09, no. 04 (2020): 236–39. http://dx.doi.org/10.1055/s-0041-1723629.

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Abstract Introduction Hodgkin’s lymphoma (HL), being one of the common cancers among children, may occasionally masquerade as an infectious illness. Similarly, an underlying infection like tuberculosis (TB) may be missed in cases of HL because of similarity in clinical and radiological features. Here, we present our data of association of HL with histopathologically proven TB lymph node, their clinical presentation, treatment details, and outcome. Materials and Methods A retrospective review of all the cases of HL diagnosed between January 2007 and December 2016 was done. The cases which had a

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Sushma, Kuppli Sai, Devi Madhavi Bhimarasetty, and Siva Kumar Lotheti. "Assessment of treatment outcome among HIV positive tuberculosis patients in Visakhapatnam." Panacea Journal of Medical Sciences 14, no. 1 (2024): 51–56. http://dx.doi.org/10.18231/j.pjms.2024.011.

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In March 2016, RNTCP revised its technical and operational guidelines. One of the major additions was introduction of Daily Regimen in the treatment of Drug sensitive TB, started initially among TB-HIV co-infected patients in 2017. The present study was taken up to assess the treatment outcomes of Tuberculosis among TB-HIV co-infected patients and certain factors related to the poorer outcome of the treatment.An Observational Longitudinal study conducted at an ART centre, attached to King George Hospital in Visakhapatnam District, Andhra Pradesh, among all TB-HIV co-infected patients newly dia

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Bhattacharjee, Soumya. "Estimation of Success Rate of Treatment of XDR-TB admitted in a Nodal DRTB Centre." Journal of Communicable Diseases 54, no. 1 (2022): 31–35. http://dx.doi.org/10.24321/0019.5138.202246.

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Background: Extensively drug-resistant TB is still a serious challenge in India, and before the introduction of new anti-tuberculosis drugs these patients were treated with a conventional regimen for XDR-TB according to the guidelines of RNTCP at that time for almost 24 to 36 months. Objective: To estimate the outcome of treatment of XDR-TB patients attended at our DRTB site and put under the conventional regimen during the period 2014-2017 according to protocol laid down by PMDT at that time i.e. 2014 to 2017.Methods: In this retrospective study, we selected 41 patients admitted with XDR-TB,

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Krishnappa, Lalitha. "Worker safety in Designated Microscopy Centers (DMC) and Tuberculosis unit (TU) under Revised National Tuberculosis Control programme (RNTCP) in state of Bihar – Contribution & Role of DTST." International Journal of Occupational Safety and Health 3, no. 1 (2013): 18–21. http://dx.doi.org/10.3126/ijosh.v3i1.6647.

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Damien Foundation India Trust (DFIT), one of the members of International Federation of Anti-Leprosy associations (ILEP) are involved in providing technical and financial support in leprosy and TB control through its projects spread across the country. While support to leprosy control started way back in 1982 through its own project, support to TB control started only in 2003. This study was part of evaluation taken to assess the role of DTST in achieving the planned objectives and to assess the impact of DFIT’s involvement in TB control. To assess the current status of worker safety in DMC/TU

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Shrestha, Rajani, Niranjan Nayak, Dharma Raj Bhatt, Deependra Hamal, and Shishir Gokhale. "Prevalence of fungal infection in clinically suspected cases of pulmonary tuberculosis visiting a tertiary care hospital." Nepal Medical College Journal 25, no. 4 (2023): 271–76. http://dx.doi.org/10.3126/nmcj.v25i4.60871.

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Pulmonary tuberculosis is the most important health concerns. Some fungi may acquire pathogenic potential in immunocompromised persons due to underlying diseases, use of prolonged antibiotics, chronic disease and malignancy. The presence of fungal pathogens in cases of pulmonary TB adds to the chronicity of the disease and being difficult to treat. This study aimed to evaluate tuberculosis (TB) status and coinfection of TB with pulmonary fungal infections. A total of 330 sputum samples were collected from suspected pulmonary TB and were examined using Ziehl-Neelsen (Z-N) staining method as per

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Pokhriyal, Bipin Chandra, Dimple Raina, Iva Chandola, Nidhi Negi, Hitendra Singh, and Vijay Kataria. "Determining the Prevalence of Rifampicin Resistant Tuberculosis in A Tertiary Care Centre of North India by using Rapid Culture Method and Gene Xpert." Journal of Pure and Applied Microbiology 15, no. 3 (2021): 1480–89. http://dx.doi.org/10.22207/jpam.15.3.42.

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The objective of the present study is to find the prevalence of Mycobacterium tuberculosis from respiratory samples like sputum, BAL and pleural fluid, compare conventional LJ culture with rapid culture method i.e Mycobacterium growth indicator tube (MGIT) and to determine the pattern of drug resistance by automated methods i.e Gene Xpert. Respiratory samples were collected in sterile, wide-mouth, disposable, leak proof containers without any preservatives. Specimens were inoculated into MGIT for primary isolation of Mycobacteria. The specimen was processed according to the SOP manual provided

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Arun, K. T. Sreelakshmi, Praveena S. Kumar, Ann R. Rajan, Monsy T. Mathai, C. V. Andrews Kakkanat, and Supriya B. Adiody. "Ocular toxicity of daily anti-tubercular treatment regimen: A prospective observational study." Kerala Journal of Ophthalmology 36, no. 2 (2024): 137–42. http://dx.doi.org/10.4103/kjo.kjo_61_23.

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Context: India carries a significant burden of TB which is the commonest cause of infectious disease-related mortality. Anti-tubercular drugs can cause serious ocular toxic effects. Optical coherence tomography (OCT) can be used as a valuable tool in the quantitative analysis of anti-tubercular treatment (ATT)-induced toxic optic neuropathy. Aims: To study the changes in visual parameters in patients on ATT and to analyze the OCT changes in patients by taking measurements once before initiation of treatment and once during ongoing treatment (between three and six months). Settings and Design:

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Paikray, Elisha, Manoranjan Pattnaik, Vedvyas Mishra, Parida Ansuman Abhisek, Shweta Supriya Pradhan, and Anima Rout. "Evaluation of health-related quality of life and adherence among pre-extensively drug-resistant tuberculosis patients receiving either Bedaquiline or Delamanid regimen at a teaching hospital in Eastern India." Journal of Family Medicine and Primary Care 13, no. 10 (2024): 4684–92. http://dx.doi.org/10.4103/jfmpc.jfmpc_572_24.

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ABSTRACT Background: The foremost concern and challenge in managing drug-resistant tuberculosis is ensuring a high health-related quality of life (HRQoL). The effectiveness of pre-extensively drug-resistant (Pre-XDR) tuberculosis management hinges on patients adhering to therapy, a crucial factor in averting the development of drug-resistant strains, ultimately enhancing HRQoL. Methodology: This analytical longitudinal study spanned two years at a teaching hospital and involved collaboration between the Departments of Pharmacology and Pulmonary Medicine. A case record form was utilized to gath

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Advait, Mohan, Kumar Suresh, and K. Bhatnagar Anuj. "Assessment of Nutritional Status, Initial Haematological Parameters and Sociodemographic Factors in New Sputum Positive Pulmonary Tuberculosis Patients and Their Correlation with Treatment Outcome." International Journal of Pharmaceutical and Clinical Research 15, no. 9 (2023): 1310–31. https://doi.org/10.5281/zenodo.11386789.

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<strong>Purpose:</strong> The purpose of the study was to find out the correlation between the initial nutritional status, initial haematological parameters, and sociodemographic factors and the treatment outcome at the end of 6 months of anti-tubercular therapy of the patients enrolled in the study.  <strong>Materials & Methods:</strong> 100 new sputum positive Pulmonary TB patients were enrolled and the initial nutritional status of the patients was assessed with height, weight and BMI. Other anthropometric indices such as Waist Hip ratio, Mid Upper Arm Circumference, Wais

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Aggarwal, J., and J. Batra. "A study on role of oxidative stress and nutrients in patients with pulmonary tuberculosis in a tertiary health care hospital." CARDIOMETRY, no. 25 (February 14, 2023): 1272–77. http://dx.doi.org/10.18137/cardiometry.2022.25.12721277.

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Background: The association between TB, oxidative stress and dietary supplements is multidirectional. The inflammation associated pathology in tuberculosis leads to the development of the free radical generation. Methods: A cross-sectional study design was selected for the study. This study was carried out in the Department of Biochemistry, Santosh Medical College, Ghaziabad. A total of 75 subjects will be enrolled from department of respiratory medicine from Santosh hospital, Ghaziabad and were divided into 3 groups as 75 healthy individuals of either sex as controls, 75 newly diagnosed patie

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Indumathi, C. K., Saurav Jain, Savita Krishnamurthy, and Beninja Alexander. "Utility of RNTCP (NTEP) guidelines in microbiological confirmation of pediatric tuberculosis." Indian Journal of Tuberculosis, June 2021. http://dx.doi.org/10.1016/j.ijtb.2021.06.007.

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MD, Dr Bhagwan Waskel. "A cross sectional study to determine the effectiveness and compliance of the new guidelines of RNTCP." Journal of Medical Science And clinical Research 7, no. 7 (2019). http://dx.doi.org/10.18535/jmscr/v7i7.10.

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Girijesh, Kumar. "A Hospital based Survey Assessing Awareness about National Tuberculosis Programmes and Antitubercular Drugs among final year MBBS Students: An Observational Study." March 30, 2022. https://doi.org/10.5281/zenodo.12514707.

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<strong>Aim: </strong>The aim of the present study was to assess the awareness about National Tuberculosis Programmes and Antitubercular drugs among final year MBBS students. <strong>Methods: </strong>A questionnaire-based study was performed among 100 final year MBBS students after obtaining clearance from the Institutional Ethics Committee. <strong>Results: </strong>Most of the participants were aware about the most common symptom of Pulmonary TB, first line antitubercular drugs, common side effects, and that TB is a notifiable disease. Regarding questions on newer d

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Kamle, Akshay, Nilesh Jain, Pramila Ramawat, and Hemant Jain. "A STUDY OF EVALUATION OF CARTRIDGE BASED NUCLEIC ACID AMPLIFICATION TEST (CBNAAT) IN PAEDIATRIC PATIENTS SUSPECTED OF TUBERCULOSIS IN A TERTIARY CARE HOSPITAL IN CENTRAL INDIA." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, June 1, 2023, 24–26. http://dx.doi.org/10.36106/ijsr/4714920.

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Background: Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. Pediatric patients are underdiagnosed and underreported, have a signicantly high mortality risk. CBNAAT is a good diagnostic method to detect mycobacterium tubercule bacilli (MTB). Material and methods: A Prospective observational study was conducted in a tertiary care hospital. 171 pediatric patients with clinical features suggestive of presumptive pulmonary or extrapulmonary tuberculosis based on RNTCP guidelines were included in the study. Relevant demographic, clinical and laboratory details were record

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Swain, Satish, Arvind Kumar, Vishal Kumar Vishwakarma, Adarsh Aayilliath K, Ankit Mittal, and Naveet Wig. "Diagnosis and Management of Latent Tuberculosis Infection: Updates." Infectious Disorders - Drug Targets 24 (November 28, 2023). http://dx.doi.org/10.2174/0118715265275319231124053615.

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Abstract: India has the largest problem of tuberculosis (TB) infection globally (estimated at about 35-40 crores cases), and around 18-36 lakh develop active tuberculosis annually. Latent TB is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifested active TB. The progression of a latent infection to active tuberculosis increases several-fold in children < 5 years of age and in people with some or the other form of an immunocompromising condition. Therefore, to cater to this gigantic problem of tubercul

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Hemanth Kumar, Agibothu Kupparam, Alok Kumar, Thiruvengadam Kannan, et al. "Pharmacokinetics of Second-Line Antituberculosis Drugs in Children with Multidrug-Resistant Tuberculosis in India." Antimicrobial Agents and Chemotherapy 62, no. 5 (2018). http://dx.doi.org/10.1128/aac.02410-17.

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ABSTRACTWe studied the pharmacokinetics of levofloxacin (LFX), pyrazinamide (PZA), ethionamide (ETH), and cycloserine (CS) in children with multidrug-resistant tuberculosis (MDR-TB) who were being treated according to the Revised National TB Control Programme (RNTCP) guidelines in India. This observational, pharmacokinetic study was conducted in 25 children with MDR-TB at the Sarojini Naidu Medical College, Agra, India, who were being treated with a 24-month daily regimen. Serial blood samples were collected after directly observed administration of drugs. Estimations of plasma LFX, PZA, ETH,

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Chavan, Reshma P., Shivraj M. Ingole, Anish Anto Parokaran, Wilson V. Desai, and Ajay P. Damodhar. "ENT manifestation CCs in tuberculosis: a descriptive study." Egyptian Journal of Otolaryngology 38, no. 1 (2022). http://dx.doi.org/10.1186/s43163-022-00330-x.

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Abstract Background An attempt was made to study ENT manifestations in tuberculosis. Material and methods A descriptive study was carried out among 200 patients with ENT manifestations of tuberculosis attending various departments at a government medical college hospital. Patients will be evaluated and followed up according to protocol. All patients diagnosed with tuberculosis were treated, according to the recent RNTCP guidelines using the CBNAAT testing. Results In the present study, 66% of patients with tuberculosis of the ear, nose, and throat region were females. Seventy-five percent of p

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SINDHU, NITIKA. "PSORIASIFORM DRUG ERUPTION INDUCED BY ANTI-TUBERCULOSIS MEDICATION: A CASE REPORT." International Journal of Current Pharmaceutical Research, January 15, 2023, 68–69. http://dx.doi.org/10.22159/ijcpr.2023v15i1.2075.

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Objective: Psoriasiform drug eruptions can be induced by several drugs. Psoriasis is a chronic inflammatory disease characterized by T-cell-mediated cytokine production that drives the hyperproliferation and abnormal differentiation of keratinocytes. Drugs can cause new lesions when there is no prior history or family history of psoriasis. Based on the psoriatic drug eruption probability score, β‐blockers, synthetic anti‐malarial drugs, non‐steroidal anti‐inflammatory drugs (NSAIDs), lithium, digoxin and tetracycline antibiotics are relevant in psoriasis. Methods: A 58-year-old male was

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N. Saiyed, Mohammed Ayaz, Mathew Varghese, Harshal Adinath Patil, and Ram Sudhan S. "A Prospective Study of 18F-FDG PET-CT Application in Therapeutic Monitoring of Osteoarticular Tuberculosis." Journal of Health Science and Medical Research, January 16, 2024, 20231027. http://dx.doi.org/10.31584/jhsmr.20241027.

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Objective: Confident diagnosis, identification of occult sites, assessing treatment response, and precisely ascertaining the duration and endpoint of treatment in skeletal tuberculosis is often challenging. magnetic resonance imaging (MRI) and computed tomography (CT) are less dependable owing to low sensitivity and the inability to discern current illness and old changes. 18F-FDG PET/CT utilizes variations in glycolysis rates between healthy and diseased tissue to quantitatively estimate the maximal standard uptake value (SUVmax) of 18F-FDG to assess disease activity.Material and Methods: 32

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N. Saiyed, Mohammed Ayaz, Mathew Varghese, Harshal Adinath Patil, and Ram Sudhan. "A Prospective Study of 18F-FDG PET-CT Application in Therapeutic Monitoring of Osteoarticular Tuberculosis." Journal of Health Science and Medical Research, January 16, 2024, 20231027. http://dx.doi.org/10.31584/jhsmr.20231027.

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Objective: Confident diagnosis, identification of occult sites, assessing treatment response, and precisely ascertaining the duration and endpoint of treatment in skeletal tuberculosis is often challenging. magnetic resonance imaging (MRI) and computed tomography (CT) are less dependable owing to low sensitivity and the inability to discern current illness and old changes. 18F-FDG PET/CT utilizes variations in glycolysis rates between healthy and diseased tissue to quantitatively estimate the maximal standard uptake value (SUVmax) of 18F-FDG to assess disease activity.Material and Methods: 32

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Juganya, TP Jai, PL Alagammai, and TP Jei Karthykayani. "Incidence and Clinical Profile of Antituberculosis Treatment-Induced Hepatitis in a Tertiary Care Hospital in Southern India." JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2020. http://dx.doi.org/10.7860/jcdr/2020/46053.14132.

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Introduction: Tuberculosis (TB) is a major health problem. After the widespread use of Antituberculosis Treatment (ATT) effective control has been achieved. As with any drug ATT has its own side effects among which hepatitis is of main concern as it can cause significant morbidity and mortality. Aim: To assess the incidence of hepatitis in patients receiving ATT as per Revised National Tuberculosis Control Programme (RNTCP) and to know the possible risk factors for the development of drug-induced hepatotoxicity. Materials and Methods: This study was done on 318 presumed and confirmed cases of

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Jakasania, Arjunkumar, Kalpita Shringarpure, Dixit Kapadia, et al. "“Side effects--part of the package”: a mixed methods approach to study adverse events among patients being programmatically treated for DR-TB in Gujarat, India." BMC Infectious Diseases 20, no. 1 (2020). http://dx.doi.org/10.1186/s12879-020-05660-w.

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Abstract Background High rates of Adverse Events (AEs) during treatment is one of the leading causes of unsuccessful treatment outcomes among patients with drug resistant tuberculosis (DR-TB). However, information related to AEs is not systematically collected and managed under programmatic setting. The present study assessed the a) incidence and pattern of adverse events in first three months of DR-TB treatment initiation; b) treatment seeking behaviour for AE management; and c) explore the challenges in seeking treatment and reporting AEs. Methods This mixed methods study included all patien

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"Rifampicin Induced Hyperbilirubinemias: A Case Report." SunKrist Clinical and Medical Case Reports Journal, November 25, 2019, 1–4. http://dx.doi.org/10.46940/scmcrj.01.1003.

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Abstract Anti-tubercular therapy (ATT) induced hepatitis is a major problem which a physician encounters in his clinical practice. A case of 28-year old female, weighing 45 kg was brought to hospital with the chief complains of low-grade fever for the past two months, cough, shortness of breath and 4-5 kg weight loss in two months. She had no history of hypertension (HTN), diabetes mellitus (DM), pulmonary tuberculosis (PTB). Her Chest X-ray showed right sided bilateral pulmonary TB and sputum acid fast bacilli (AFB) smear was repeatedly positive. Pulmonologist has started Category-I anti-tube

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Patel, Robinkumar, Parul Vadgama, and Khyati Shamaliya. "Effectiveness of anti-tuberculosis drugs in tuberculosis and HIV co-infected patients coming to tertiary health-care center in South Gujarat." National Journal of Physiology, Pharmacy and Pharmacology, 2023, 1. http://dx.doi.org/10.5455/njppp.2023.13.08418202329092023.

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Background: Tuberculosis (TB) and human immunodeficiency virus (HIV) are major public health problems in most of the developing countries, including India. For developing TB, HIV infection is one of the strongest risk factors. The presentation and outcome of TB are affected by HIV infection. Aims and Objectives: The objective is to study the type of TB, level of CD4 count, TB presentation in TB-HIV patients. Observation of anti-TB treatment, adverse drug reactions (ADR), and outcome of anti-TB treatment in patients with TB-HIV co-infection. Materials and Methods: The present study is an observ

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Dubba, Sunitha, Suresh Babu Sayana, Mounika Vadithya, M. Sravan Kumar, I. Sridhar, and Meela Ranjith Kumar. "Role of Corticosteroids in Tubercular Pleural Effusion: A Prospective Interventional Study from a Tertiary Care Teaching Hospital, Telangana, India." JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2022. http://dx.doi.org/10.7860/jcdr/2022/57821.16726.

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Introduction: Tuberculosis is a major public health problem in majority of the developing countries. Pleural effusion develops when fluid accumulates between the parietal and visceral pleura. Aim: To evaluate the efficiency of corticosteroids in rapid clinical and radiological resolution of TPE. Also to study the recurrence of pleural effusion and find incidence of pleural fibrosis in patients treated with corticosteroids. Materials and Methods: This prospective interventional study was conducted at Government Chest Diseases and TB hospital (tertiary care teaching hospital), Telangana, India,

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