Academic literature on the topic 'Rocuronium; Hypotension; Severe obesity'

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Journal articles on the topic "Rocuronium; Hypotension; Severe obesity"

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Fabio, Silvio Mario Araimo Morselli. "Severe Repeated Hypotension Occurred after Rocuronium Administrations in a Morbidly Obese Patient: A Case Report." Global Journal of Anesthesiology 1, no. 1 (2014): 013–15. https://doi.org/10.17352/2455-3476.000003.

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Rocuronium has the most rapid onset of action among the nondepolarizing neuromuscular blocking drugs; doses of 0.6-0.9 mg/ Kg guarantee a complete block in about 60-90 seconds and good or excellent intubating conditions in 60 seconds [1,2]. Its pharmacokinetics and pharmacodynamics can be influenced by different factors as age, inhaled anesthetics, hepatic and renal insufficiency, hypothermia, gender and obesity [3-8]. Rocuronium has been shown to cause less histamine release and cardiovascular instability than benzylisoquinolinum neuromuscular blocking agents such as atracurium and mivacurium
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Ishihara, Honoka, Yukie Nitta, Yoko Kudo, and Kanta Kido. "Anaphylaxis After a Third Exposure to Sugammadex." Anesthesia Progress 72, no. 2 (2025): 95–99. https://doi.org/10.2344/24-0013.

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We report a rare case of anaphylaxis triggered by a third exposure to sugammadex. The patient was a 49-year-old man who had previously been exposed to sugammadex on two occasions and then developed likely anaphylaxis (severe hypotension and skin, gastrointestinal, and respiratory symptoms) after administration of sugammadex following bilateral mandibular alveoloplasty. He was promptly and successfully managed and recovered fully without any complications. A subsequent sugammadex drug-induced lymphocyte stimulation test was negative. The mechanism via which sugammadex causes anaphylaxis is not
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Ahtil, Redouane, Marouane Jidal, Walid Atmani, et al. "SUGAMMADEX: A NOVEL APPROACH IN THE MANAGEMENT OF ROCURONIUM-INDUCED ANAPHYLAXIS DURING ANESTHESIA INDUCTION." International Journal of Advanced Research 12, no. 12 (2024): 984–88. https://doi.org/10.21474/ijar01/20108.

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Anaphylaxisis a rapid-onset, potentially life-threateningsystemichypersensitivityreaction, with an estimated incidence of 1 in 20,000 anesthetic administrations. Neuromuscularblocking agents (NMBAs), particularlyrocuronium and succinylcholine, are implicatedin 60–70% of anestheticanaphylaxis cases. Prompt recognition and intervention are critical in these emergencies. Sugammadex, a selectiveantagonist of rocuronium, offers a noveltherapeuticapproach due to itsability to rapidlyencapsulaterocuroniummolecules, effectivelymitigating the immunologicalprocessesdrivinganaphylaxis. This report pres
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Ahmed Amine JAOUAHAR, Achraf MOUSSA, Hatim BELFQUIH, et al. "Acute kidney injury due to perioperative rhabdomyolysis during meningioma surgery." World Journal of Advanced Research and Reviews 25, no. 2 (2025): 2351–54. https://doi.org/10.30574/wjarr.2025.25.2.0625.

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Acute kidney injury (AKI) due to perioperative rhabdomyolysis is a rare but severe complication that can occur during prolonged surgical procedures, especially in patients with predisposing factors such as obesity, diabetes, and metabolic disorders. This case report describes a 40-year-old woman with a history of non-insulin-dependent diabetes and obesity, who developed AKI following a 10-hour meningioma surgery. During the operation, she received low-dose anesthetic agents, including propofol and rocuronium. Postoperatively, she developed oliguric acute kidney injury, accompanied by hyperkale
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Yang, Ting, Muhammad Saqib Mudabbar, Mingxing Xu, Qingmei Xiang, Bin Liu, and Qiang Fu. "The effects of esketamine on blood pressure and hypotension incidence during induction of bariatric surgery: A randomized controlled trial." Medicine 102, no. 51 (2023): e36754. http://dx.doi.org/10.1097/md.0000000000036754.

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Background: The prevalence of obesity is high. Bariatric surgery is an effective treatment for severe obesity; however, the induction phase of anesthesia in these patients poses a risk of hypotension. Esketamine, known for its sympathetic nervous system stimulation, may stabilize blood pressure during induction. This study aimed to investigate the effects of esketamine on blood pressure in bariatric surgery patients. Methods: This randomized controlled trial included 145 patients undergoing bariatric surgery. Patients were randomly assigned to receive esketamine or a control intervention durin
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Greco, Massimiliano, Pier Francesco Caruso, Giovanni Angelotti, et al. "REVersal of nEuromusculAr bLocking Agents in Patients Undergoing General Anaesthesia (REVEAL Study)." Journal of Clinical Medicine 12, no. 2 (2023): 563. http://dx.doi.org/10.3390/jcm12020563.

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Background: Neuromuscular blocking agent (NMBA) monitoring and reversals are key to avoiding residual curarization and improving patient outcomes. Sugammadex is a NMBA reversal with favorable pharmacological properties. There is a lack of real-world data detailing how the diffusion of sugammadex affects anesthetic monitoring and practice. Methods: We conducted an electronic health record analysis study, including all adult surgical patients undergoing general anesthesia with orotracheal intubation, from January 2016 to December 2019, to describe changes and temporal trends of NMBAs and NMBA re
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Shabanova, Gulel, Elvan Onan, Ebru Biricik, Feride Karacaer, Demet Laflı Tunay, and Yasemin Güneş. "Effects of Controlled Hypotension on Cerebral Oxygenation in Tympanoplasty and Tympanomastoidectomy Surgery." Cukurova Anestezi ve Cerrahi Bilimler Dergisi 7, no. 4 (2024): 229–34. https://doi.org/10.36516/jocass.1537759.

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Background: Controlled hypotension can reduce bleeding and improve visualization of the surgical field. We aimed to evaluate the effects of deliberate controlled hypotension by using esmolol and nicardipine on cerebral oxygenation, hemodynamics, bleeding, surgical satisfaction and quality of recovery. Methods: Sixty patients between the ages of 18 and 65 who were scheduled tympanomastoidectomy surgery were included. Anesthesia induction was performed with propofol, rocuronium and general anesthesia was maintained with sevoflurane and remifentanil infusion. The mean arterial blood pressure was
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Wicaksono, Satrio Adi, Taufik Eko Nugroho, and Sulistiyati Bayu Utami. "Anaesthetic management in the patient with thoracic–lumbar intradural tumor accompanied by heart failure and atrial fibrillation: a case report." Bali Medical Journal 11, no. 3 (2022): 1282–88. http://dx.doi.org/10.15562/bmj.v11i3.3514.

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Background: Spinal cystic intradural Schwannoma is a type of tumor that is rarely found, with an incidence of 0.3–0.5/100,000 person per year. The operative procedure for this tumor was simple. However, some patients showed other comorbidities, such as heart failure with low ejection fraction (EF) and atrial fibrillation. Such cases are a challenge to the anaesthesiologist as they are most commonly complicated by progressive cardiac failure. Case Presentation: A 68-year-old woman was consulted by the Anaesthesiology Department in dr. Kariadi General Hospital Semarang in April 2019. She had bee
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Athul, Krishna S. A.¹ Assish P. Antony² Benson P. Wilson*³ Sona Sojan⁴ Happy Thomas⁵. "Cardiovascular And Metabolic Abnormalities Induced By Antipsychotic Drug Therapy And Their Management Strategies." International Journal in Pharmaceutical Sciences 2, no. 4 (2024): 680–87. https://doi.org/10.5281/zenodo.10964677.

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Cardiovascular disease is the leading cause of death in people with severe mental disorders. Reports of sudden death in patients receiving antipsychotic treatment have raised concerns about the safety of antipsychotic drugs. Antipsychotic medications can induce cardiovascular and metabolic abnormalities (such as obesity, hyperglycemia, dyslipidemia and the metabolic syndrome) that are associated with an increased risk of type 2 diabetes mellitus and cardiovascular disease. The direct, non-specific pharmacological actions of antipsychotic drugs can lead to adverse cardiovascular effects, includ
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Martini, Francesca, Marta Bosia, Mariachiara Buonocore, et al. "M202. SEX-RELATED DIFFERENCES IN CLOZAPINE SIDE EFFECTS IN PATIENTS WITH TREATMENT-RESISTANT SCHIZOPHRENIA." Schizophrenia Bulletin 46, Supplement_1 (2020): S213. http://dx.doi.org/10.1093/schbul/sbaa030.514.

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Abstract Background Treatment resistant schizophrenia (TRS) affects up to 30% of patients with psychosis and is a major cause of disability. Although clozapine is the only indicated drug for TRS, it is largely underused, partially due to its life-threatening adverse effects (AEs) as agranulocytosis and myocarditis. However, clozapine treatment is also burdened by other AEs as constipation, hypersalivation, postural hypotension, tachycardia, metabolic abnormalities and weight gain. In recent years many efforts have been made to outline clinical and neurobiological characteristics of TRS. Althou
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Book chapters on the topic "Rocuronium; Hypotension; Severe obesity"

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Jong, Audrey de, and Samir Jaber. "Obesity." In Oxford Textbook of Respiratory Critical Care. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/med/9780198766438.003.0054.

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Abstract Summary Obese patients admitted to the intensive care unit (ICU) are at risk of pulmonary complications, mainly because of their predisposition to atelectasis. Non-invasive ventilation (NIV) has proven its safety and efficacy to treat and/or prevent acute respiratory failure. Use of high-flow nasal cannula oxygen (HFNC) allows warm, humidified oxygen to be administered and provides a moderate level of positive end-expiratory pressure (PEEP). Mask ventilation and intubation are more difficult in obese than in non-obese patients. Then, a protocol of difficult airway management should be
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