Relevant bibliographies by topics / ROPE matrix

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'ROPE matrix'

Author: Grafiati
Published: 4 June 2021
Last updated: 19 February 2022

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Journal articles on the topic "ROPE matrix"

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Kuismin, M. O., J. T. Kemppainen, and M. J. Sillanpää. "Precision Matrix Estimation With ROPE." Journal of Computational and Graphical Statistics 26, no. 3 (May 25, 2017): 682–94. http://dx.doi.org/10.1080/10618600.2016.1278002.

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Liang, Jun, Chunjing Wu, Hang Ping, Ming Wang, and Weizhong Tang. "Surface Pretreatment and Fabrication Technology of Braided Carbon Fiber Rope Aluminum Matrix Composite." Metals 10, no. 9 (September 9, 2020): 1212. http://dx.doi.org/10.3390/met10091212.

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Carbon fiber is mainly distributed in the shape of short fibers and continuous fiber bundles as the reinforcing phase in metal matrix composites, and it is seldom studied as braided rope shaped to reinforce the matrix. For this paper, the pretreatment and the surface metallization of the carbon fiber braided rope were studied. Besides, the casting experiments of aluminum-based carbon fiber braided rope composites were performed without external pressure. XPS analysis shows that the surface of the carbon fiber braided rope treated with ultrasonic degumming contains many hydrophilic oxygen-containing functional groups C-OH, C=O, COOH, etc., which can effectively improve the wettability between the carbon fiber braided rope and the aluminum matrix. SEM, EDS, and XRD were used to analyze the micromorphology and structure of the copper plating on the surface of carbon fiber braided ropes obtained from different pH plating solutions. When pH is 12, a continuous, uniform, and dense layer was formed on the surface of carbon fiber braided ropes. In addition, copper coating can effectively inhibit the formation of Al4C3 brittle phase. Finally, the mechanical properties results indicated that the tensile strength of the carbon fiber bundle and carbon fiber rope reinforced composite materials were 69 MPa and 83 MPa, respectively, indicating that the reinforcing effect of the carbon fiber rope is better than that of the carbon fiber bundle.
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Zhao, Yun Peng, and Nan Li. "Research on Coordinate System Transformation in Flexible Rope FEA." Advanced Materials Research 753-755 (August 2013): 1785–89. http://dx.doi.org/10.4028/www.scientific.net/amr.753-755.1785.

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This paper focuses on the transform relationships between each element and between elements with inertial system under different attitude coordinate system in the finite element multi-body system mechanical analysis of the flexible rope process. It mainly research the attitude coordinate transformation matrix between the of flexible rope Micro-element and inertial system under the four coordinate system which are the direction cosine coordinates, finite rotation four element coordinates, Euler angle coordinate and Cardan angle coordinates, and the relationship between the connecting base on the element type and inertial reference based.
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Stawowiak, Michał, Marcel Żołnierz, and Zenon Rożenek. "The use of flat steel-polymer supporting ropes in mining multi-pole hoisting devices." New Trends in Production Engineering 2, no. 1 (October 1, 2019): 168–77. http://dx.doi.org/10.2478/ntpe-2019-0017.

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Abstract The paper presents the development of a series of flat steel and polymer bearing ropes using a polyurethane polymeric material (the name of NPSP – flat steel-polyurethane). These ropes are intended for mining extraction devices with friction drive (multi-mill drive wheel, multi-rope drums with a number of ropes from 3 to 12 pieces). The authors of this article have presented a comparison of the drive power of a selected multi-mine mine hoist device with a classic steel round rope with the same extractor in which steel and polymer flat carrying ropes were used. The article also presents the development of mining construction of hoisting equipment, which includes the use of new rope ropes. Very positive results from exploitation in Polish mining of flat steel-rubber balance ropes (durability up to 12 years) can be the basis for the use of such ropes as supporting ropes. Flat steel-polymer supporting ropes, in which the matrix can be rubber or polyurethane or other plastic material, could contribute to increasing the durability of load-bearing ropes due to anti-corrosion protection as well as to reduce the dimensions of drive wheels and rope hoisting machines, and thus to lower the power of the winding machine (as a result of reducing the moments of inertia of the propeller, propulsion and rope). It is also worth mentioning that the NPSP carrying ropes can work directly on steel coatings of propeller drums with proper positioning, created by clamping elements (wood, plastic or aluminum blocks).
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Tihonov, Evgeniy. "MATRIX CAGES HOLDING SYSTEM FOR INDUSTRIAL FISH FARMING." Fisheries 2020, no. 1 (February 26, 2020): 93–99. http://dx.doi.org/10.37663/0131-6184-2020-1-93-99.

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In the paper, the technical aspects of modeling the retention system of matrixtype cages for industrial fish farming in a pond is considered. To date, there is no developed calculation methodology that takes into account the layout features of each cage module. The layout of the modules can vary significantly: from 1 to 36 cages of various designs. The aim of the work is to substantiate the parameters of the holding ropes, the length of the pull chains and the required mass of anchors by calculating the tensile forces in the ropes and the reaction of the anchor supports when solving the dynamic task in an unsteady setting. To solve this problem, a dynamic system was developed considering wind, wave, and inertial loads acting on all elements of the system: cage, holding ropes, chains, anchors. The force acting on the surface of the cage from the wind is received. The values of tensile forces in the ropes, the reaction of the supports of the anchors in three planes are obtained. The lengths of the chains are identified, ensuring the absence of tearing forces acting on the anchors. The masses of anchors are calculated taking into account the Archimedean force, depending on the density of the anchors’ material. The simulation lasted for 60 s. At 37 seconds of calculation, a resonant phenomenon was revealed: a significant increase in the breaking strength in the rope.
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Ren, Y., F. Li, H. M. Cheng, and K. Liao. "Fatigue Behaviour of Unidirectional Single-Walled Carbon Nanotube Reinforced Epoxy Composite under Tensile Load." Advanced Composites Letters 12, no. 1 (January 2003): 096369350301200. http://dx.doi.org/10.1177/096369350301200103.

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Tension-tension fatigue behaviour of unidirectional, aligned single-walled carbon nanotube (SWNT) rope reinforced epoxy composites were studied. While the slope of the stress-life (S-N) curve of the SWNTs in SWNT/epoxy composites obtained is flat, similar to those of carbon fibre reinforced epoxy composites, the fatigue strength of the former is at least twice that of the latter. Morphology of the fatigue fracture surface of SWNT reinforced epoxy involves matrix plastic deformation and SWNT-bridged matrix cracks. Evidence of good adhesion between SWNTs and epoxy was seen, and pullout length of SWNTs from the matrix is about 30 μm. Results suggest that carbon nanotubes can be used for fatigue resistant, high fracture toughness composites.
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Zhang, Donglai, Min Zhao, Zhihui Zhou, and Shimin Pan. "Characterization of Wire Rope Defects with Gray Level Co-occurrence Matrix of Magnetic Flux Leakage Images." Journal of Nondestructive Evaluation 32, no. 1 (December 28, 2012): 37–43. http://dx.doi.org/10.1007/s10921-012-0156-6.

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Zhang, Yang, Duanwei Shi, Lekang Liao, Lang Shi, and Xionghao Cheng. "Pitch stability analysis of high-lift wire rope hoist vertical shiplift under shallow water sloshing–structure interaction." Proceedings of the Institution of Mechanical Engineers, Part K: Journal of Multi-body Dynamics 233, no. 4 (June 8, 2019): 942–55. http://dx.doi.org/10.1177/1464419319850666.

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Pitch stability under shallow water sloshing–structure interaction has always been the most concerned issue in the design of the high-lift wire rope hoist vertical shiplift, which brings great challenges to the operational safety. A semi-analytical method including the developed modal system and the new coupled dynamics model is presented for pitch stability analysis. Based on the linear modal theory, the modal system is developed to describe the shallow water sloshing in the shiplift chamber, and the hydrodynamic moment associated with infinite set of modal functions is reasonably simplified by only retaining the lowest mode. Then a new 9-DOF coupled dynamics model of the complete main hoist system, shiplift chamber motion, and shallow water sloshing is established as dynamic equations by using the Lagrange equation of the second kind. Subsequently, the coefficient matrix of the dynamic equations and the Lyapunov motion stability theory are used in combination to numerically obtain the critical distance of suspension points. Taking four typical high-lift wire rope hoist shiplifts as an example, the results indicate that the proposed scheme improves the computational accuracy by 7.0–20.8% with respect to previous methods. Furthermore, for the being designed 200 m level wire rope hoist vertical shiplift, the preliminary design parameters can ensure the pitch stability safety factor not less than 1.3, increasing the wire rope stiffness or the synchronous shaft stiffness can effectively enhance the pitch stability.
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Wan, Jiaxin, Qi Wang, Siyao Zang, Xin'an Huang, Tao Wang, Guoqing Liu, Chunsheng Li, and Xiaomin Ren. "Highly stretchable and sensitive liquid-type strain sensor based on a porous elastic rope/elastomer matrix composite structure." Composites Science and Technology 182 (September 2019): 107707. http://dx.doi.org/10.1016/j.compscitech.2019.107707.

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Ouyang, Huimin, Xin Deng, Huan Xi, Jinxin Hu, Guangming Zhang, and Lei Mei. "Novel robust controller design for load sway reduction in double-pendulum overhead cranes." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 233, no. 12 (November 20, 2018): 4359–71. http://dx.doi.org/10.1177/0954406218813383.

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It is seen that when the hook mass is larger than the load mass or the load has distributed mass property, the load sway of the crane system presents as double-pendulum effect. In this situation, crane system has two different natural frequencies so that the sway characteristic becomes more complex and greatly increases the difficulty of the dynamic performance analysis and controller design. Moreover, the rope length changes significantly affect the stability and control performance of the crane system. In order to solve the aforementioned problems, the linear dynamics of a two-dimensional overhead crane with double-pendulum effect is derived based on a disturbance observer, and is decoupled for controller design by modal analysis. Next, a state feedback controller is presented to achieve robust control performance for a given range of rope length changes. The controller gains are obtained via linear matrix inequality optimization method. Finally, numerical simulations and experimental results validate that the proposed method has superior control performance.
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Dissertations / Theses on the topic "ROPE matrix"

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Rodríguez, Escribà Marta. "Role of tRNA modifications in the synthesis of the extracellular matrix." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/668499.

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Transfer RNAs (tRNAs) are key adaptor molecules that mediate decoding of messenger RNAs (mRNAs) into proteins by complementary pairing of their anticodons with mRNA codons. tRNAs that undergo adenosine to inosine editing at the wobble base, or position 34, display expanded codon decoding capacity as inosine enables pairing not only with uridine, but also with cytosine and adenosine. The essential heterodimeric enzyme Adenosine Deaminase Acting on Transfer RNA (ADAT) catalyzes this post-transcriptional modification in eukaryotes and is comprised of subunits ADAT2 and ADAT3. Emergence of heterodimeric ADAT has been proposed to have shaped both tRNA gene content and codon composition of eukaryotic genomes in such a way that these two features became mirrored. Although the exact contribution of wobble inosine (I34) to translation elongation has not been established, previous reports have suggested that it might play a role in improving translational efficiency and accuracy of genes enriched in codons recognized by I34-modified tRNAs. To further understand the role of the inosine modification in translation, we generated cell lines depleted in the catalytic subunit ADAT2. Silencing of ADAT2 lead to impaired cellular proliferation and had a variable impact on the expression of genes coding for extracellular matrix (ECM) proteins such as mucins. Notably, ADAT2 deficiency did not have major effects on the post-translational glycosylation of mucins, neither did it trigger the unfolded protein response. Supported by the absence of clear defects in decoding rates in ADAT2 depleted cells, as measured by ribosome profiling, our findings suggest that a reduced pool of I34-modified tRNAs might suffice to carry out cellular functions in steady-state conditions. However, we found that, under circumstances involving a high demand for these tRNAs such as airway remodeling, ADAT2 is required for the proper translation of an ECM gene enriched in stretches of codons read by I34-tRNAs. Taken together, our results suggest that the inosine modification is particularly relevant for the synthesis of ECM proteins during specialized processes including neural development and airway remodeling. The importance of the inosine modification has been recently underscored by the identification of pathogenic mutations in the gene encoding ADAT3, all of which share common neurodevelopmental phenotypes. The most prevalent mutation identified to date is a valine to methionine (V144M) substitution that is linked to intellectual disability and strabismus. In the present study we characterized human ADAT in terms of activity and quaternary structure, and investigated the effect of the ADAT3 V144M mutation on the enzyme. We showed that the V144M substitution leads to decreased enzymatic activity of ADAT, which might result from alterations in the tertiary structure and subcellular localization of ADAT3 that were found to be associated to the mutation.
Els ARNs de transferència (ARNt) són molècules que tenen un paper clau en el procés de traducció dels ARN missatgers (ARNm) en proteïnes mitjançant la interacció del seu anticodó amb codons d’ARNm. Els ARNt que passen per un procés d’edició d’adenosina a inosina a la base wobble, o posició 34, són capaços de llegir més d’un codó d’ARNm gràcies a la capacitat de la inosina de reconèixer els tres nucleòtids uridina, citidina i adenosina. L’enzim responsable d’aquesta modificació post-transcripcional en eucariotes s’anomena Adenosina Deaminasa específica per l’ARNt (ADAT), es tracta d’un complex heterodimèric format per les subunitats ADAT2 i ADAT3 que és essencial per a la viabilitat de l’organisme. Estudis previs han proposat que l’aparició d’ADAT va determinar el nombre de còpies gèniques de cada ARNt així com la composició de codons presents als genomes eucariòtics de tal manera que aquests dos factors estiguessin mútuament balancejats. Tot i que la contribució precisa de la inosina 34 (I34) a la traducció de proteïnes durant la fase d’elongació encara s’ha determinat experimentalment, algunes investigacions han suggerit que podria jugar un rol en l’eficiència i fidelitat de traducció de gens enriquits en codons reconeguts per ARNt modificats amb I34. Amb l’objectiu d’investigar el rol de la inosina en la traducció, hem generat línies cel·lulars on el gen codificant per ADAT2 ha estat silenciat. La depleció d’ADAT2 comporta un retard en el creixement cel·lular i té un efecte variable en l’expressió gènica de proteïnes de la matriu extracel·lular. El patró de modificacions post-traduccionals de glicosilació d’aquestes proteïnes no resulta alterat per la deficiència d’ADAT2, que tampoc activa la resposta a proteïnes desplegades. Juntament amb l’absència de defectes en la velocitat d’elongació analitzada per ribosome profiling, aquestes observacions suggereixen que la cèl·lula és capaç de dur a terme les seves funcions amb un nombre reduït d’ARNt modificats amb inosina. Hem vist, però, que en condicions que requereixen majors quantitats d’ARNt inosinats, la depleció d’ADAT2 dóna lloc a la traducció ineficient d’un gen de matriu extracel·lular altament enriquit en codons sensibles llegits per ARNt modificats. Així doncs, els nostres resultats indiquen que la inosina pot exercir un rol important en la síntesi de proteïnes de la matriu extracel·lular, particularment durant processos de desenvolupament neuronal i de remodelat de les vies respiratòries. La rellevància de la modificació I34 s’ha vist reforçada recentment per la identificació de mutacions de caire patogènic localitzades al gen que codifica ADAT3. Totes elles tenen en comú la presència de fenotips relacionats amb el desenvolupament neurològic. La mutació d’ADAT3 més comuna consisteix en la substitució d’un residu valina per un metionina (V144M) i està associada a la manifestació de discapacitat intel·lectual i estrabisme. En el present estudi hem caracteritzat l’activitat enzimàtica i l’estructura quaternària de l’ADAT humà, així com l’impacte de la mutació V144M d’ADAT3 en el complex heterdimèric. Els nostres revelen que la substitució V144M dóna lloc a una menor activitat enzimàtica d’ADAT. És possible que aquesta reducció es vegi influïda per les alteracions en l’estructura terciària i en la localització cel·lular d’ADAT3 que indueix la mutació.
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Stanton, Heather. "The role of matrix metalloproteinases in cell-matrix interactions." Thesis, Open University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284376.

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Gregory, Jeremy R. (Jeremy Ryan) 1976. "The role of precipitates on fiber/matrix interfaces in metal matrix composites." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/89301.

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Bear, Harriet Mary. "The role of tyrosine rich acidic matrix protein in the extracellular matrix." Thesis, University of Edinburgh, 1997. http://hdl.handle.net/1842/21534.

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A number of purification strategies were performed in an attempt to produce highly purified, active TRAMP free from lysyl oxidase for fibrillogenesis and enzymatic studies. TRAMP was eventually purified by DEAE anion exchange followed by Superdex-75 size exclusion (in the presence of urea) and Mono Q FPLC anion exchange chromatography. Yields of 10μg of TRAMP per g wet weight starting material were obtained. TRAMP purified as above was active in fibrillogenesis assays using the 'warm start' technique, in buffers containing 30mM TES, 30mM Na2HPO4, 135mM NaCl pH 7.4. The acceleratory effect of TRAMP on collagen I fibril formation was also observed when the phosphate concentration was lowered to 10mM and when TES was removed. TRAMP has previously been shown to bind to in vitro reconstituted collagen fibrils if present during their formation. Reducing the phosphate concentration decreased the amount of TRAMP associated with collagen I fibrils in co-sedimentation assays, whilst subsequent removal of TES had no effect on TRAMP binding to collagen I fibrils. Preliminary observations also suggested that treatment of TRAMP with sulphatase had no effect on the ability of TRAMP to accelerate collagen I fibril formation. A solid phase assay showed TRAMP to bind collagen I monomers with a higher affinity than fibrils, suggesting a role for TRAMP in the early, nucleation phase of fibril formation. TRAMP was unable to reverse the inhibitory effect of decorin on fibril formation. The presence of decorin had no effect on TRAMP binding to collagen monomers in solid phase assays but led to an increase in the amount of TRAMP associated with collagen fibrils in co-sedimentation assays. Attempts to identify specific binding sites for TRAMP on in vitro reconstituted collagen I fibrils by immunogold labelling and electron microscopy were unsuccessful. Western blot analysis of murine tissues confirmed previous reports that TRAMP was present in lung and skeletal muscle and absent in brain and spleen.
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Molik, Bablin. "Role of matrix metalloproteinases in uveoscleral outflow." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/54613/.

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Prostaglandin derivatives form the most widely used medicinal treatments given to glaucoma patients to lower intraocular pressure. Prostaglandins are believed to increase matrix metalloproteinase (MMP) and tissue inhibitor of matrix metalloproteinase (TIMP) activity, leading to increased in aqueous outflow, via uveoscleral outflow pathway. However, the direct impact of MMPs on the tissues within uveoscleral pathway has not been determined. The aim of this project was to compare the direct effect of prostaglandins and MMPs on the tissues within the uveoscleral outflow pathway. To determine the effect of known inducers of MMP activity, scleral fibroblasts and ciliary muscle cells were cultured in the presence of interleukin-1a, tumour necrosis factor, transforming growth factor p and prostaglandin F2a (PGF2a). The effect of prostaglandin F2a and MMPs on the uveoscleral pathway tissue i.e. sclera, was assessed as a measure of permeability, molecular and supramolecular scleral collagen integrity and proteoglycan composition. A significant induction of MMP 1, 2, 3 and 9 secretion and activity with cytokines and PGF2a, within human scleral fibroblast and ciliary muscle cell cultures (p<0.05). A 3-fold increase in scleral permeability was observed within 24 hour of incubation in PGF2a, whereas upto 10-fold increase was observed in MMP treated. The helical rise per residue (at 1.5nm), lateral packing (at 0.29nm) and D-spacing (at 66nm) of scleral collagen was unaffected by MMP and PGF2a incubation. Significant change in aggrecan degradation was observed within scleral tissue incubated in MMP and PGF2a (p<0.05). However, no significant change in small leucine rich proteoglycans i.e. biglycan, decorin and lumican, within sclera occurred within sclera incubated in MMP or PGF2a.
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Staines, Katherine Ann. "Role of MEPE in chondrocyte matrix mineralisation." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/8157.

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Matrix Extracellular Phosphoglycoprotein (MEPE) is a member of a family of proteins called small integrin-binding ligand, N-linked glycoproteins (SIBLINGs) which play key roles in biomineralisation. Altered MEPE expression is associated with several phosphate and bone-mineral metabolic disorders such as oncogenic osteomalacia and hypophosphatemic rickets. Despite this, it remains undetermined what impact MEPE has on the growth plate; the cartilage anlagen from which endochondral ossification, the process responsible for linear bone growth, occurs. The work of this thesis has characterised the ATDC5 cell line and the metatarsal organ culture as useful in vitro models of endochondral ossification. These will prove vital in the pursuit of underpinning the molecular mechanisms involved in endochondral bone growth. These models form the basis of the further studies in this thesis examining the role of MEPE within this highly orchestrated process. Before such role can be defined, this thesis details the spatial and temporal localisation patterns of MEPE in 10-day- and 4-week-old murine growth plates. More specifically, MEPE protein and mRNA were preferentially expressed by the hypertrophic chondrocytes as shown by immunohistochemistry and in situ hybridisation respectively. Microdissection of the murine growth plate confirmed this. Localisation of the cleavage product of MEPE, a 2.2kDa acidic serine- and aspirate-rich motif (ASARM) peptide, followed a similar pattern of expression. The localisation of MEPE to sites of mineralisation serves to strengthen its potential role in chondrocyte matrix mineralisation. This thesis identified this role in both mineralising ATDC5 cells and the metatarsal organ culture. The ASARM peptide was found to be the functional component of MEPE and this function was dependent upon its post-translational phosphorylation. Phosphorylated (p)ASARM peptides significantly inhibited chondrocyte matrix mineralisation without altering the proliferation or differentiation of the chondrocyte cells, or their ability to produce an extracellular matrix. mRNA analysis by qPCR indicted a feedback system by which the pASARM peptide functions to allow the release of further ASARM peptides. Moreover, the pASARM peptide inhibited mRNA expression of markers of vascular angiogenesis highlighting a novel mechanism by which they may inhibit chondrocyte matrix mineralisation. This thesis also determines the regulatory cross-talk between the chondrocytes of the murine growth plate, with the most abundant bone cell type, the osteocyte. This cross-talk inhibits chondrocyte matrix mineralisation and is attributed to sclerostin, an osteocyte-specific secretory protein. Furthermore, it is shown that sclerostin acts through the MEPE-ASARM axis to regulate chondrocyte matrix mineralisation and thus endochondral ossification. The work described herein has characterised and validated in vitro models of growth plate chondrocyte matrix mineralisation and has used these to identify the role of MEPE within chondrocyte matrix mineralisation.
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Behzadi, Shabnam. "Role of matrix yield in composite performance." Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434485.

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Leonardo, Christopher C. "The Role of Extracellular Matrix and Matrix-Degrading Proteases in Neonatal Hypoxic-Ischemic Injury." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002587.

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Lytras, Theodoros 1987. "The Role of occupational exposures in Chronic Obstructive Pulmonary Disease." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/586017.

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Introduction: Occupational exposures are considered to be one of the newer and important risk factors for Chronic Obstructive Pulmonary Disease (COPD) besides tobacco smoking. However, the evidence mostly comes from smaller and cross-sectional studies and important questions remain unanswered, such as which specific exposures are responsible, the magnitude of the risk involved, and how the risk varies between men and women and between smokers and nonsmokers. The aim of this thesis was to examine the association between objectively assessed occupational exposures and changes in COPD-related outcomes over two decades in the European Community Respiratory Health Survey (ECRHS), a large multicentre population-based longitudinal study. Methods: General population samples aged 20-44 years were randomly enrolled in the ECRHS between 1991 and 1993, and twice followed up over the course of 20 years. Complete job histories during this follow-up were linked to the ALOHA(+) Job-Exposure Matrix, generating occupational exposures to 12 categories of agents. Spirometries were performed at each study visit. The outcomes of interest were: lung function decline, chronic bronchitis incidence and post-bronchodilator COPD incidence. Results: Exposure to biological dust, gases & fumes and pesticides was associated with higher COPD incidence, with 21% of all COPD cases attributable to these three agents. Pesticides were associated with higher incidence of chronic phlegm but only in women, and gases & fumes and solvents also with chronic phlegm but only in men. Mineral dust exposure was associated with higher chronic phlegm incidence and metals exposure with hicher chronic bronchitis incidence, in both sexes. All studied exposures except solvents were associated with accelerated decline in the FEV1/FVC ratio, particularly in male smokers. Women exposed to biological dust also tended to have higher declines in FVC, as did men exposed to pesticides. Conclusions: A substantial proportion of the total COPD burden is attributable to occupational exposures. The effect of occupation on COPD-related outcomes is complex, and depends on exposure type, sex and smoking status. Further research is warranted to provide more details about the observed associations.
Introducció: Les exposicions ocupacionals es consideren un dels factors de risc importants per a la malaltia pulmonar obstructiva crònica (MPOC) juntament amb tabaquisme. No obstant això, l'evidència prové principalment d'estudis de mida petita i transversals i preguntes importants segueixen sense resposta, per exemple quines exposicions específiques són responsables, la magnitud del risc involucrat i com el risc varia entre homes i dones o entre fumadors i no fumadors. L'objectiu d'aquesta tesi és examinar l'associació entre exposicions ocupacionals objectivament avaluades i els canvis en els resultats relacionats amb la MPOC durant dues dècades en l'Enquesta de Salut Respiratòria de la Comunitat Europea (ECRHS), un gran estudi longitudinal multicèntric poblacional. Mètodes: La mostra de la població general amb edats compreses entre 20 i 44 anys es va seleccionar aleatòriament a l’ECRHS entre 1991 i 1993, i a els participants se’ls hi va fer seguiment dues vegades en el transcurs de 20 anys. L'historial complet de treballs durant el període de seguiment es va vincular amb la Matriu d'Ocupació-Exposició ALOHA (+), generant estimacions d'exposicions ocupacionals a 12 categories d'agents. Les espirometries es van realitzar en cada visita d'estudi. Els resultats d'interès van ser: disminució de la funció pulmonar, incidència de bronquitis crònica i incidència de MPOC després de broncodilatació. Resultats: L'exposició a pols, gasos i fums biològics i pesticides es va associar amb una major incidència de MPOC, amb un 21% de tots els casos de MPOC atribuïbles a aquests tres agents. Els pesticides es van associar amb una major incidència d’expectoració crònica, però només en les dones, i gasos i fums i dissolvents també amb expectoració crònica, però només en els homes. L'exposició a la pols mineral es va associar amb una major incidència d’expectoració crònica i l’exposició a metalls amb incidència de bronquitis crònica, en ambdós sexes. Totes les exposicions estudiades, excepte els dissolvents, es van associar amb una disminució accelerada de la relació FEV1 / CVF, (VEMS/CVF) particularment en fumadors homes. Les dones exposades a la pols d'origen biològic també van tenir majors disminucions en la capacitat vital forçada (CVF), igual que els homes exposats als pesticides. Conclusions: Una proporció important dels casos de MPOC és atribuïble a exposicions ocupacionals. L'efecte de l'ocupació en els resultats relacionats amb la MPOC és complex i depèn del tipus d'exposició, el sexe i el tabaquisme. Es requereix més investigació per proporcionar més infromació sobre les associacions observades
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Garcia, Puig Anna. "Study of extracellular matrix remodeling and the role of periostin b during zebrafish heart regeneration." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/666564.

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Adult zebrafish (Danio rerio), in contrast to mammals, are able to regenerate their hearts in response to injury or experimental amputation. Our understanding of the cellular and molecular bases that underlie this process, although fragmentary, has increased significantly over the last years. However, the role of the extracellular matrix (ECM) during zebrafish heart regeneration has been comparatively rarely explored. A better understanding of all the mechanisms underlying this complex process would help developing strategies to regenerate the human heart. With this aim, here, we set out to characterize the ECM protein composition in adult zebrafish hearts, whether it changed during the regenerative response, and the role of the matricellular protein periostin b. For this purpose, in the first part of the current thesis, we established a decellularization protocol of adult zebrafish ventricles that significantly enriched the yield of ECM proteins. We then performed proteomic analyses of decellularized control hearts and at different times of regeneration. Our results show a dynamic change in ECM protein composition, most evident at the earliest (7 days post-amputation) time-point analyzed. Regeneration associated with sharp increases in specific ECM proteins, and with an overall decrease in collagens and cytoskeletal proteins. We finally tested by atomic force microscopy that the changes in ECM composition translated to decreased ECM stiffness. Our cumulative results identify changes in the protein composition and mechanical properties of the zebrafish heart ECM during regeneration. In the second part of the current thesis, we have examined the role of periostin b (postnb) during zebrafish heart regeneration. We found that postnb was abundant in the injury of amputated zebrafish ventricles, and we designed two strategies to suppress postnb during regeneration: 1) a shRNA transgenic knock-down, and 2) a CRISPR/Cas9 postnb-/- zebrafish. Knock-down and knock-out fishes did not exhibit any evident developmental defects, but showed a lack complete cardiac regeneration after amputation. The absence of postnb did not have any effect on leukocyte recruitment, matrix metalloproteinase activation or revascularization after amputation. However, postnb-/- zebrafish developed a softer cardiac ECM due to a reduction of collagen cross- linking, and showed an increase of cardiomyocyte proliferation and a decrease on cardiomyocyte cell death after amputation. The stiffness control by postnb seem to be important to correctly modulate stiffness for a complete cardiac regeneration. Stiffness analysis toguether with proliferation analysis suggest that postnb is needed to increase the stiffness in the injury border to instruct cardiomyocytes to stop proliferating and migrate to the injury site.
El peix zebra adult (Danio rerio) és capaç, contràriament als mamífers, de regenerar el seu cor en resposta a una lesió o amputació experimental. La comprensió de les bases cel·lulars i moleculars subjacents a aquest procés ha augmentat significativament en els últims anys, encara que segueix sent fragmentària. Tot i així, el paper de la matriu extracel·lular (MEC) durant la regeneració cardíaca del peix zebra ha estat rarament explorat. Una millor comprensió de tots els mecanismes subjacents a aquest complex procés podria ajudar a desenvolupar estratègies per a regenerar el cor humà. Amb aquest objectiu, es va proposar caracteritzar la composició proteica de la MEC en cors de peix zebra adults, els possibles canvis existents durant la resposta regenerativa, i el paper de la proteïna matricel·lular periostin b (postnb). A aquest efecte, a la primera part de la present tesis, es va establir un protocol de descel·lularització de ventricles de peix zebra adults, que va aconseguir un enriquiment significatiu en el contingut en proteïnes de la MEC. A continuació, es va realitzar un anàlisi proteòmics de cors control descel·lularitzats i en diferents moments del procés de regeneració per avaluar els canvis proteics. Els nostres resultats mostren un canvi dinàmic en la composició proteica de la MEC, més evident a temps més inicial del procés de regeneració analitzat (7 dies després de l'amputació). Així, la regeneració cardíaca es va associar a un increment de proteïnes especifiques de la MEC, i a una reducció generalitzada de col·làgens i proteïnes citoesquelètiques. Finalment, es va analitzar per Atomic Force Microscopy els canvis en la duresa de la MEC produïts per aquests canvis observats de composició. El nostre conjunt de resultats identifiquen canvis en la composició proteica i les propietats mecàniques de la MEC cardíaca durant la regeneració. A la segona part de la present tesis, es va examinar el paper de la periostin b (postnb) durant la regeneració cardíaca del peix zebra. La seva presència era abundant a la ferida de ventricles amputats, i es van dissenyar dues estratègies per a suprimir la postnb durant la regeneració: 1) un knock-down (KD) mitjançant shRNAs, i 2) un knock- out (KO) per CRISPR/Cas9. Ni la línia KD ni la KO exhibien cap defecte del desenvolupament, però demostraven una clara deficiència en el procés de regeneració després de l’amputació del ventricle. La absència de la postnb no va demostrar cap efecte sobre el reclutament de leucòcits, l’activació de les metaloproteases de matriu (MMP), o la revascularització després de l’amputació. Tot i així, els peixos postnb-/- van desenvolupar una MEC més tova degut a una reducció del cross-linking del col·lagen. Alhora, van demostrar un increment de la proliferació i una reducció de l’apoptosi dels cardiomiòcits després de l’amputació. El control de la duresa de la MEC efectuat per la postnb sembla ser important per modular correctament aquesta propietat mecànica per a una regeneració cardíaca completa. Els anàlisis de duresa conjuntament amb els anàlisis de proliferació suggereixen que la postnb és necessària per a un increment de la duresa en la vora de la ferida. Així, seria requerida per a instruir als cardiomiòcits per parar de proliferar i migrar cap a la ferida.
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Books on the topic "ROPE matrix"

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Kuruba, Mahesh. Role Competency Matrix. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7.

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Lessan, Khashayar. The role of extracellular matrix in angiogenesis. Manchester: University of Manchester, 1996.

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Aristarkhova, I. Hospitality of the matrix: Philosophy, biomedicine, and culture. New York: Columbia University Press, 2012.

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Lee, Vivian. Matrix molecules play a role in mediating chondrocyte aggregation, attachment and spreading. Ottawa: National Library of Canada, 2000.

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Kachigan, Sam Kash. The sexual matrix: Boy meets girl on the evolutionary scale. New York: Radius Press, 1990.

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Kachigan, Sam Kash. The sexual matrix: Boy meets girl on the evolutionary scale. New York: Radius Press, 1990.

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Transexualidad y la matriz heterosexual: Un estudio crítico de Judith Butler. Barcelona: Edicions Bellaterra, 2009.

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Soley-Beltran, Patrícia. Transexualidad y la matriz heterosexual: Un estudio crítico de Judith Butler. Barcelona: Edicions Bellaterra, 2009.

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Pearce, Andrew G. The role of the matrix attachment region (MAR) in the regulation of mammalian DNA replication. Sudbury, Ont: Laurentian University, 1998.

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Srivastava, Jitendra. Medicinal plants: An expanding role in development. Washington, D.C: World Bank, 1996.

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Book chapters on the topic "ROPE matrix"

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Faignet, Stephane, Frank Theys, and Jan Wastiels. "Increasing Energy Absorption by “Rope Effect” in Brittle Matrix Composites." In Mechanical Identification of Composites, 398–405. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3658-7_45.

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Kuruba, Mahesh. "Role Competency Matrix—Applications." In Role Competency Matrix, 77–101. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_6.

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Kuruba, Mahesh. "Introduction." In Role Competency Matrix, 1–7. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_1.

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Kuruba, Mahesh. "People Management Challenges." In Role Competency Matrix, 9–16. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_2.

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Kuruba, Mahesh. "Competency Management." In Role Competency Matrix, 17–26. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_3.

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Kuruba, Mahesh. "Measuring Competency." In Role Competency Matrix, 27–48. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_4.

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Kuruba, Mahesh. "The Role Competency Matrix." In Role Competency Matrix, 49–75. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_5.

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Kuruba, Mahesh. "Implementing RCM." In Role Competency Matrix, 103–31. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_7.

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Kuruba, Mahesh. "Change Management." In Role Competency Matrix, 133–39. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_8.

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Kuruba, Mahesh. "RCM Analytics." In Role Competency Matrix, 141–65. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-7972-7_9.

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Conference papers on the topic "ROPE matrix"

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O’Rourke, Brian J., Mark K. Fuglem, and Tony King. "3-D Simulation of Iceberg Towing Operations: Cable Modeling and Frictional Contact Formulation Using Finite Element Analysis." In ASME 2020 39th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/omae2020-18788.

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Abstract Ice management in regions of offshore development with icebergs present includes re-direction of icebergs by means of towing. The prevention of tow-rope slippage and iceberg rolling due to hydrostatic instability are essential for an effective and safe operation. The ability to simulate any particular towing operation in the field, prior to attempting it, would provide some measure of assurance of its feasibility. In addition, such a model will allow optimization of towing configuration and application by showing optimal tow direction, maximum force and rate of force application; selection of single tow line or net; and optimum net configuration. The objective of the described work is to develop a simulation tool that can be used for such application. A previous project funded by Hibernia Management and Development Company Ltd. (HMDC) gathered 3-dimensional profile data on 29 icebergs off the East coast of Canada; and further data collection has been ongoing. The present project utilizes these profiles as valuable input in the development of the model for simulating single-line and net tows. This paper presents the first phase of development of a 3-D dynamic iceberg towing model that evolved from an earlier 2-D static version. The current iteration applies the ‘Total Lagrangian’ Finite-Element Method (FEM) to model the cable-and-rope structure between the towing vessel and iceberg, and a contact model that includes sticking and sliding friction between the rope/net and iceberg. The iceberg is modeled as a rigid surface mesh and is fully constrained against motion during the current phase of development, while the cables and ropes are modeled as elastic bar elements with translational inertia and velocity-squared fluid drag. The contact elements consist of penalty springs with proportional damping, and appropriate values of these are found to be critical for numerical stability of the solution. As well, due to the large difference in stiffness values between the heavy tow cable and buoyant ropes, special attention is given to obtaining the initial tangent stiffness matrix of the cable-and-rope structure. The FE dynamic equations of motion are solved implicitly in the time domain using a combination of full and modified Newton-Raphson iteration. Simulations of contact initiation between the rope and iceberg for single-loop and net configurations are presented, as well as slipping during particular single-loop tows. Current challenges and opportunities for further development are discussed, including improving computational speed, implementing iceberg motion, adding wind and wave forces, and validating rope-ice friction characteristics through small-scale iceberg towing response in a laboratory.
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Wasfy, Tamer M., Hatem M. Wasfy, and Jeanne M. Peters. "Real-Time Explicit Flexible Multibody Dynamics Solver With Application to Virtual-Reality Based E-Learning." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48743.

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A flexible multibody dynamics explicit time-integration parallel solver suitable for real-time virtual-reality applications is presented. The hierarchical “scene-graph” representation of the model used for display and user-interaction with the model is also used in the solver. The multibody system includes rigid bodies, flexible bodies, joints, frictional contact constraints, actuators and prescribed motion constraints. The rigid bodies rotational equations of motion are written in a body-fixed frame with the total rigid body rotation matrix updated each time step using incremental rotations. Flexible bodies are modeled using total-Lagrangian spring, truss, beam and hexahedral finite elements. The motion of the elements is referred to a global inertial Cartesian reference frame. A penalty technique is used to impose joint/contact constraints. An asperity-based friction model is used to model joint/contact friction. A bounding box binary tree contact search algorithm is used to allow fast contact detection between finite elements and other elements as well as general triangular/quadrilateral rigid-body surfaces. The real-time solver is used to model virtual-reality based experiments (including mass-spring systems, pendulums, pulley-rope-mass systems, billiards, air-hockey and a solar system) for a freshman university physics e-learning course.
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Barendregt, Wolmet, Mathilde M. Bekker, Peter Börjesson, Eva Eriksson, and Olof Torgersson. "The Role Definition Matrix." In IDC '16: Interaction Design and Children. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/2930674.2935999.

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Merchan, L. R., J. M. Lozano Garcia, A. Pizano-Martinez, E. A. Zamora-Cardenas, H. J. Estrada-Garcia, and L. C. Razo-Vargas. "Output filter control for matrix converter in synchronous applications." In 2016 IEEE International Autumn Meeting on Power, Electronics and Computing (ROPEC). IEEE, 2016. http://dx.doi.org/10.1109/ropec.2016.7830577.

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Merchan-Villalba, L. Ramon, Cristian A. Carreno-Meneses, A. Pizano-Martinez, E. Arnoldo Zamora-Cardenas, X. Gonzalez-Ramirez, and Jose M. Lozano-Garcia. "Load-side DVR based on matrix converter for deep voltage sags compensation." In 2017 IEEE International Autumn Meeting on Power, Electronics and Computing (ROPEC). IEEE, 2017. http://dx.doi.org/10.1109/ropec.2017.8261676.

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Magana-Lemus, Ernesto, Aurelio Medina-Rios, and Antonio Ramos-Paz. "Periodic steady state solution of power systems by selective transition matrix identification and graphic processing units." In 2014 IEEE International Autumn Meeting on Power, Electronics and Computing (ROPEC). IEEE, 2014. http://dx.doi.org/10.1109/ropec.2014.7036339.

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V., L. Ramon Merchan, C. A. Carreno M., A. Pizano M., E. Arnoldo Zamora C., V. Javier Gutierrez M., and J. Merced Lozano G. "Matrix Converter for Grid Applications with Controllable Input Reactive Power based on the Singular Value Decomposition Modulation." In 2018 IEEE International Autumn Meeting on Power, Electronics and Computing (ROPEC). IEEE, 2018. http://dx.doi.org/10.1109/ropec.2018.8661388.

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Gutierrez-Torres, D. Armando de Jesus, Jose M. Lozano-Garcia, L. Ramon Merchan-Villalba, Alejandro Pizano-Martinez, and Jesus Martinez-Patino. "Low Cost Practical Implementation of a Three-Phase Matrix Converter." In 2019 IEEE International Autumn Meeting on Power, Electronics and Computing (ROPEC). IEEE, 2019. http://dx.doi.org/10.1109/ropec48299.2019.9057065.

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Gautam, P. S., and K. K. Mohanty. "Role of Fracture Flow in Matrix-Fracture Transfer." In SPE Annual Technical Conference and Exhibition. Society of Petroleum Engineers, 2002. http://dx.doi.org/10.2118/77336-ms.

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Ye, Wei, Ruixuan Li, and Huaqing Li. "Role Mining Using Boolean Matrix Decomposition with Hierarchy." In 2013 12th IEEE International Conference on Trust, Security and Privacy in Computing and Communications (TrustCom). IEEE, 2013. http://dx.doi.org/10.1109/trustcom.2013.98.

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Reports on the topic "ROPE matrix"

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Shah, Sudhir V. Role of Novel Matrix-Degrading Metalloproteinase in Breast Cancer Invasion. Fort Belvoir, VA: Defense Technical Information Center, May 2002. http://dx.doi.org/10.21236/ada407031.

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Matrisian, Lynn, and Laura Rudolph. The Role of Matrilysin, a Matrix Metalloproteinase, in Mammary Tumorigenesis. Fort Belvoir, VA: Defense Technical Information Center, September 1995. http://dx.doi.org/10.21236/ada302428.

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Angulo Rodríguez, Emilio, and Ariel Yépez-García. The Role of Natural Gas in Energy Transition. Inter-American Development Bank, November 2020. http://dx.doi.org/10.18235/0002868.

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As of 2004 and continuously to this day, the annual growth rate of renewable sources has been greater than that of all fossil fuels combined. In the midst of this transition to cleaner energy, natural gas is the only fossil fuel that has increased its share in the global energy matrix. Technological changes in the LNG supply chain, as well as transformations in the global natural gas market, largely explain this growth. This publication provides evidence on the fundamental role that natural gas plays in the energy transition, given that: (i) its greenhouse gas emissions are substantially lower than those of oil and coal; (ii) it provides the firm power necessary to complement intermittent renewable energies; (iii) it is particularly safe compared to other fossil fuels. In line with these attributes, the International Energy Agency projects that the share of natural gas in the global energy matrix by 2040 will remain stable (around 24%), even in its Sustainable Development Scenario, which would allow to meet the goals established in the Paris Agreement.
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Patch, Jared R. The Central Role of the Matrix Protein in Nipah Virus Assembly and Morphogenesis. Fort Belvoir, VA: Defense Technical Information Center, February 2007. http://dx.doi.org/10.21236/ad1014034.

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Holth, Laurel T. Role of Nuclear Matrix in Estrogen Regulated Gene Expression in Human Breast Cancer Cells. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada382697.

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Cao, Jian, and Stanley Zucker. Examination of the Role of Membrane Type-1 Matrix Metalloproteinase in Breast Cancer Metastasis. Fort Belvoir, VA: Defense Technical Information Center, August 2000. http://dx.doi.org/10.21236/ada393382.

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Cao, Jian, and Stanley Zucker. Examination of the Role of Membrane Type-1 Matrix Metalloproteinase (MTI-MMP) in Breast Cancer Metastasis. Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada398200.

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Cao, Jian, and Stanley Zucker. Examination of the Role of Membrane Type-1 Matrix Metalloproteinase (MTI-MMP) in Breast Cancer Metastasis. Fort Belvoir, VA: Defense Technical Information Center, August 1999. http://dx.doi.org/10.21236/ada384239.

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Saulnier, Ron. Regulation of Anchorage-Independent Growth in Breast Cancer. Role of Signalling by Extracellular Matrix and Growth Factors. Fort Belvoir, VA: Defense Technical Information Center, August 1995. http://dx.doi.org/10.21236/ada300473.

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Álvarez, Carola, Leonardo Corral, Ana Cuesta, José Martínez, César Montiel, and Consuelo Yépez. Project Completion Report Analysis: Factors Behind Project Success and Effectiveness. Inter-American Development Bank, March 2021. http://dx.doi.org/10.18235/0003116.

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The goal of development assistance is to deliver measurable results. At the Inter-American Development Bank (IDB), the Development Effectiveness Framework (DEF) was adopted to enhance the likelihood this goal is met. The key objective of this analysis is to enhance our understanding of the role the set of tools and processes adopted at the IDB, from project design to completion, play in the assessment of a projects success and effectiveness. Specifically, we are interested in teasing out the role different dimensions of project design, assessed through the Development Effectiveness Matrix (DEM), and execution performance indicators, as per the Project Monitoring Report (PMR), have on the delivery of effective and successful projects measured through the Project Completion Report (PCR) methodology implemented at the IDB. We also explore the validation process of PCRs and delve into the effectiveness analysis at the level of specific objectives and result indicators, identifying key pitfalls associated with objectives not being met. Overall, our findings provide strong validation for the DEF and its tools. We find robust evidence for the importance of the quality at entry assessment conducted through the DEM. In particular, the quality of the results matrix at approval is a strong determinant of project success and effectiveness at closure, and the quality of the Evaluation Plan is strongly associated with the effectiveness of a project. In terms of execution performance, our analysis finds that, on average, projects that execute a lower share of their approved loan amount, are put on Alert, or are classified as a Problem, in its first three years of execution; and projects that experience a higher share of their outputs discontinued, with respect to their first results matrix, are most likely to be ineffective in achieving their objectives and will likely be rated as unsuccessful.
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