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Journal articles on the topic 'Rosiglitazone'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Okami, Nobuya, Purnima Narasimhan, Hideyuki Yoshioka, et al. "Prevention of JNK Phosphorylation as a Mechanism for Rosiglitazone in Neuroprotection after Transient Cerebral Ischemia: Activation of Dual Specificity Phosphatase." Journal of Cerebral Blood Flow & Metabolism 33, no. 1 (2012): 106–14. http://dx.doi.org/10.1038/jcbfm.2012.138.

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Rosiglitazone, a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist, prevents cell death after cerebral ischemia in animal models, but the underlying mechanism has not been clarified. In this study, we examined how rosiglitazone protects neurons against ischemia. Mice treated with rosiglitazone were subjected to 60 minutes of focal ischemia followed by reperfusion. Rosiglitazone reduced infarct volume after ischemia and reperfusion. We show that this neuroprotective effect was reversed with a PPARgM antagonist. Western blot analysis showed a significant increase in expressi

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2

Bogatkevich, Galina S., Kristin B. Highland, Tanjina Akter та Richard M. Silver. "The PPARγAgonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects". Pulmonary Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/545172.

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We present novel data demonstrating that the expression of PPARγis reduced in lung fibroblasts from black SSc-ILD patients as compared to white patients. Activating PPARγwith the agonist rosiglitazone increased the expression of MMP-1 and inhibited collagen type I in lung fibroblasts isolated from white, but not black, SSc-ILD patients. Blocking the c-Met receptor abolishes rosiglitazone's effects on collagen and MMP-1 in lung fibroblasts isolated from white SSc-ILD patients, while augmenting the expression of the c-Met receptor in fibroblasts from black SSc-ILD patients replicates the effects

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3

Lu, Wenyi, Kaiyan Liu, Weimin Wang, Shujuan Wang, and Yonghuai Feng. "Long-Term Treatment with Rosiglitazone Delays Hematopoietic Recovery in Response to Stress." Blood 126, no. 23 (2015): 4769. http://dx.doi.org/10.1182/blood.v126.23.4769.4769.

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Abstract Rosiglitazone is a peroxisome proliferator activated receptor-γ(PPAR-γ) agonist available to improve glucose metabolism in patients with Type 2 diabetes. Recent evidence suggests that therapeutic use of rosiglitazone have caused unwanted hematological side effects, such as anemia, leukopenia, thrombocytopenia, even pancytopenia. However, others reported that pretreatment with rosiglitazone for 5 days could protect against 5-Fu-induced myelotoxity which is FLT3 dependent. Thus, it is still unclear the exact effects of rosiglitazone treatment on homeostatic and stress hematopoiesis. Ros

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4

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1180 (2007): 34. http://dx.doi.org/10.2165/00128415-200711800-00107.

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&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1186 (2008): 33. http://dx.doi.org/10.2165/00128415-200811860-00106.

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6

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1127 (2006): 21. http://dx.doi.org/10.2165/00128415-200611270-00070.

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7

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1143 (2007): 21. http://dx.doi.org/10.2165/00128415-200711430-00070.

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&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 788 (2000): 9–10. http://dx.doi.org/10.2165/00128415-200007880-00030.

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9

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 788 (2000): 10. http://dx.doi.org/10.2165/00128415-200007880-00031.

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10

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 850 (2001): 11. http://dx.doi.org/10.2165/00128415-200108500-00028.

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11

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1400 (2012): 37. http://dx.doi.org/10.2165/00128415-201214000-00137.

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12

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1199 (2008): 40–41. http://dx.doi.org/10.2165/00128415-200811990-00123.

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13

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1206 (2008): 27. http://dx.doi.org/10.2165/00128415-200812060-00088.

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14

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1081 (2005): 24. http://dx.doi.org/10.2165/00128415-200510810-00076.

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&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1086 (2006): 23. http://dx.doi.org/10.2165/00128415-200610860-00070.

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16

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1088 (2006): 20–21. http://dx.doi.org/10.2165/00128415-200610880-00063.

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17

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1091 (2006): 20. http://dx.doi.org/10.2165/00128415-200610910-00059.

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18

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1093 (2006): 30–31. http://dx.doi.org/10.2165/00128415-200610930-00104.

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19

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1110 (2006): 15–16. http://dx.doi.org/10.2165/00128415-200611100-00050.

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20

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1111 (2006): 20. http://dx.doi.org/10.2165/00128415-200611110-00059.

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21

Barman Balfour, Julia A., and Greg L. Plosker. "Rosiglitazone." Drugs 57, no. 6 (1999): 921–30. http://dx.doi.org/10.2165/00003495-199957060-00007.

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22

Mooradian, Arshag D. "Rosiglitazone." Drugs 57, no. 6 (1999): 931–32. http://dx.doi.org/10.2165/00003495-199957060-00008.

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23

Wolffenbuttel, Bruce H. R. "Rosiglitazone." Drugs 57, no. 6 (1999): 931–32. http://dx.doi.org/10.2165/00003495-199957060-00009.

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24

Wagstaff, Antona J., and Karen L. Goa. "Rosiglitazone." Drugs 62, no. 12 (2002): 1805–37. http://dx.doi.org/10.2165/00003495-200262120-00007.

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25

Deeks, Emma D., and Susan J. Keam. "Rosiglitazone." Drugs 67, no. 18 (2007): 2747–79. http://dx.doi.org/10.2165/00003495-200767180-00008.

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26

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 885 (2002): 10. http://dx.doi.org/10.2165/00128415-200208850-00033.

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27

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 890 (2002): 11. http://dx.doi.org/10.2165/00128415-200208900-00043.

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28

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 916 (2002): 11. http://dx.doi.org/10.2165/00128415-200209160-00033.

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&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1279 (2009): 30. http://dx.doi.org/10.2165/00128415-200912790-00088.

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&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1283 (2010): 81. http://dx.doi.org/10.2165/00128415-201012830-00259.

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31

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1245 (2009): 32–33. http://dx.doi.org/10.2165/00128415-200912450-00100.

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&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1249 (2009): 40–41. http://dx.doi.org/10.2165/00128415-200912490-00123.

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33

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1255 (2009): 29. http://dx.doi.org/10.2165/00128415-200912550-00083.

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34

Krentz, Andrew J. "Rosiglitazone." Drugs 71, no. 2 (2011): 123–30. http://dx.doi.org/10.2165/11585300-000000000-00000.

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35

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 943 (2003): 10. http://dx.doi.org/10.2165/00128415-200309430-00040.

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36

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 966 (2003): 14–15. http://dx.doi.org/10.2165/00128415-200309660-00043.

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37

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 975 (2003): 13. http://dx.doi.org/10.2165/00128415-200309750-00035.

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38

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1288 (2010): 35. http://dx.doi.org/10.2165/00128415-201012880-00108.

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39

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1297 (2010): 45. http://dx.doi.org/10.2165/00128415-201012970-00137.

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40

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1302 (2010): 42. http://dx.doi.org/10.2165/00128415-201013020-00133.

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41

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1018 (2004): 13. http://dx.doi.org/10.2165/00128415-200410180-00040.

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42

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1031 (2004): 13. http://dx.doi.org/10.2165/00128415-200410310-00038.

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43

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1054 (2005): 16. http://dx.doi.org/10.2165/00128415-200510540-00054.

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44

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1060 (2005): 14. http://dx.doi.org/10.2165/00128415-200510600-00043.

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45

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1066 (2005): 9. http://dx.doi.org/10.2165/00128415-200510660-00022.

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46

&NA;. "Rosiglitazone." Reactions Weekly &NA;, no. 1351 (2011): 38. http://dx.doi.org/10.2165/00128415-201113510-00135.

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47

Cada, Dennis J., Danial E. Baker, and Terri Levien. "Rosiglitazone." Hospital Pharmacy 34, no. 11 (1999): 1322–39. http://dx.doi.org/10.1177/001857879903401112.

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48

&NA;. "Rosiglitazone." Drugs & Therapy Perspectives 14, no. 6 (1999): 1–5. http://dx.doi.org/10.2165/00042310-199914060-00001.

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49

Simon, Dominique. "Rosiglitazone." Primary Care Diabetes 3, no. 2 (2009): 123–24. http://dx.doi.org/10.1016/j.pcd.2009.05.002.

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50

Wolffenbuttel, Bruce HR, Jean-Pierre Sels, and Maya SP Huijberts. "Rosiglitazone." Expert Opinion on Pharmacotherapy 2, no. 3 (2001): 467–78. http://dx.doi.org/10.1517/14656566.2.3.467.

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