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Dissertations / Theses on the topic 'Rottlerin'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lama, Zoé. "Étude fonctionnelle d'inhibiteurs de kinases réprimant la réplication du virus de la rage." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS490.

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Alors que les étapes du cycle du virus de la rage sont plutôt bien décrites, les interactions du virus avec la machinerie cellulaire restent mal connues. Le but de ce projet de thèse a été d’identifier et caractériser les voies de signalisation cellulaires impliquées dans le déroulement du cycle viral. Les kinases cellulaires jouent un rôle majeur dans la régulation de ces voies et certaines protéines rabiques ont déjà été décrites comme cibles de ces enzymes. Afin d’identifier les kinases impliquées dans le déroulement du cycle viral, nous avons réalisé un criblage d’une banque d’inhibiteur d

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2

Sivanathan, Sivatharushan [Verfasser]. "Synthese enantiomerenreiner α-Hydroxycarbonsäuren, neuer Cyclooctadepsipeptide sowie Studien zur Totalsynthese von Rottlerin / Sivatharushan Sivanathan". Wuppertal : Universitätsbibliothek Wuppertal, 2015. http://d-nb.info/1076930166/34.

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3

Heineck, Lukas [Verfasser], and Christian [Akademischer Betreuer] Kurts. "Der Einfluss von Rottlerin auf T-Zellpräsentation und -aktivierung / Lukas Heineck ; Betreuer: Christian Kurts." Marburg : Philipps-Universität Marburg, 2019. http://d-nb.info/1199537519/34.

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4

Juneja, Manisha. "Novel insights into MACC1 transcriptional regulation for identifying small molecule MACC1 inhibitors to restrict colorectal cancer progression." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2014. http://dx.doi.org/10.18452/17038.

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MACC1 wurde als prognostischer Biomarker für die Tumorprogression und das Metastasen-freie Überleben im KRK sowie in anderen soliden Tumoren beschrieben. Das Gen induziert Zellmotilität und Proliferation in Zellkultur sowie die Metastasierung im Mausmodell. Damit stellt MACC1 ein vielversprechendes Ziel für die Intervention bei Tumorprogression und –metastasierung und damit für die Behandlung von KRK-Patienten dar. Unser Ziel war es, die Transkription von MACC1 zu inhibieren. Hierfür identifizierten wir zunächst die Promoter-Region von MACC1 und untersuchten MACC1s transkriptionelles Regulati

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5

Cordeiro, Thuany de Moura. "Efeitos da rottlerin na esquizogonia eritrocitária de Plasmodium falciparum e implementação e avaliação de teste in vitro por fluorescência de atividade antiplasmodial." reponame:Repositório Institucional da UnB, 2014. http://repositorio.unb.br/handle/10482/15666.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Patologia Molecular, 2014.<br>Submitted by Alaíde Gonçalves dos Santos (alaide@unb.br) on 2014-04-29T12:50:20Z No. of bitstreams: 1 2014_ThuanydeMouraCordeiro.pdf: 3960809 bytes, checksum: 4b394c3182d7b2be77db6f48e1225c6d (MD5)<br>Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2014-05-23T12:40:35Z (GMT) No. of bitstreams: 1 2014_ThuanydeMouraCordeiro.pdf: 3960809 bytes, checksum: 4b394c3182d7b2be77db6f48e1225c6d (MD5)<br>Made available in DSpace on 2

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6

Nguyen, Khoa Thuy Diem. "Energy metabolism in the brain and rapid distribution of glutamate transporter GLAST in astrocytes." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/3996.

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Glutamate transporters play a role in removing extracellular excitatory neurotransmitter, L-glutamate into the cells. The rate of the uptake depends on the density of the transporters at the membrane. Some studies claimed that glutamate transporters could transit between the cytoplasm and the membrane on a time-scale of minutes. The present study examined the distribution of glutamate transporter GLAST predominantly expressed in rat cortical cultured astrocytes between the membrane and the cytoplasm by using deconvolution microscopy and then analyzing the images. The regulation of the dist

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7

Nguyen, Khoa Thuy Diem. "Energy metabolism in the brain and rapid distribution of glutamate transporter GLAST in astrocytes." University of Sydney, 2008. http://hdl.handle.net/2123/3996.

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Doctor of Philosophy (Medicine)<br>Glutamate transporters play a role in removing extracellular excitatory neurotransmitter, L-glutamate into the cells. The rate of the uptake depends on the density of the transporters at the membrane. Some studies claimed that glutamate transporters could transit between the cytoplasm and the membrane on a time-scale of minutes. The present study examined the distribution of glutamate transporter GLAST predominantly expressed in rat cortical cultured astrocytes between the membrane and the cytoplasm by using deconvolution microscopy and then analyzing the

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8

Contreras, Xavier. "Rôle des voies PKC et calcium dans les productions de TNF-alpha et d'IL-10 induites par la protéine Tat du Virus de l'immuodéficience humaine chez le monocyte humain et dans la réplication de virus R5-tropiques dans le macrophage." Toulouse 3, 2005. http://www.theses.fr/2005TOU30012.

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Les objectifs de cette thèse sont d’une part la caractérisation des voies de signalisation impliquées dans la production de TNF-a et d’IL-10 par les monocytes/macrophages humains stimulés par la protéine Tat du VIH-1 et d’autre part l’évaluation du rôle de ces voies de signalisation dans la réplication virale. Ainsi, la protéine Tat active la voie calcique et la voie de la PKC dans le monocyte/macrophage pour stimuler la production du TNF-a et de l’IL-10 via son domaine N-terminal 1-45. Le domaine 20-45 stimule l’entrée du calcium dans le monocyte via les canaux calciques DHP sensibles. Tat in

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9

Koterba, Kristen L. "Regulation of Autophagy and Cell Death in Breast Carcinoma Cells." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1276005638.

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10

Rottler, Andreas [Verfasser]. "Investigation of Radial Metamaterials / Andreas Rottler." München : Verlag Dr. Hut, 2013. http://d-nb.info/1037286847/34.

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11

Lakshmanan, Aparna. "Modulation of Sodium Iodide Symporter-mediated Thyroidal Radioiodide Uptake by Small Molecule Inhibitors, Natural Plant-based Products and microRNAs." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429407914.

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12

Rottler, Klemens [Verfasser], and Josef [Akademischer Betreuer] Jochum. "Muons in the CRESST Dark Matter Experiment / Klemens Rottler ; Betreuer: Josef Jochum." Tübingen : Universitätsbibliothek Tübingen, 2014. http://d-nb.info/1196801460/34.

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13

Rottler, Philipp [Verfasser]. "Kortikale Reorganisation nach Hypoglossus-Fazialis Transfer bei Patienten mit peripherer Fazialisparese im Zusammenhang des klinischen Outcome / Philipp Rottler." Greifswald : Universitätsbibliothek Greifswald, 2014. http://d-nb.info/1052159338/34.

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14

Schneider, Ludwig [Verfasser], Marcus [Akademischer Betreuer] Müller, Marcus [Gutachter] Müller, Annette [Gutachter] Zippelius, and Jörg [Gutachter] Rottler. "Rheology and Structure Formation in Complex Polymer Melts / Ludwig Schneider ; Gutachter: Marcus Müller, Annette Zippelius, Jörg Rottler ; Betreuer: Marcus Müller." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2019. http://d-nb.info/118402104X/34.

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15

Rottler, Sarah [Verfasser], and Michael [Akademischer Betreuer] Erhard. "Verhalten als Tierschutzindikator für die vergleichende Beurteilung einer Boden- und Kombihaltung für Mastkaninchen unter Praxisbedingungen / Sarah Rottler ; Betreuer: Michael Erhard." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1191098095/34.

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16

Rottler, Erwin [Verfasser], Axel [Akademischer Betreuer] Bronstert, Gerd [Akademischer Betreuer] Bürger, Axel [Gutachter] Bronstert, Gerd [Gutachter] Bürger, and Kerstin [Gutachter] Stahl. "Transient merging of two Rhine flow regimes from climate change / Erwin Rottler ; Gutachter: Axel Bronstert, Gerd Bürger, Kerstin Stahl ; Axel Bronstert, Gerd Bürger." Potsdam : Universität Potsdam, 2021. http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-517665.

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17

Araújo, Cristina Dias. "Atividade antibacteriana in vitro e in sito de Allium tuberosum - Rottler ex sprengl (alho "nirá" ou alho "japonês", "jiucai" ou alho "chinês") - liliaceae - sobre agentes de toxinfecções alimentares." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/10842.

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Buscou-se identificar e comparar a atividade antibacteriana do extrato alcoólico de três acessos de Allium tuberosum - Rottler ex Sprengl – Liliaceae - originários da região metropolitana de Porto Alegre/RS frente a agentes de toxinfecções alimentares, especificamente: Staphylococcus aureus (ATCC 25.923), Enterococcus faecalis (ATCC 19.433), Salmonella Enteritidis (ATCC 11.076) Escherichia coli (ATCC 11.229). Inicialmente, in vitro, através de Teste de Diluição, por meio de Sistema de Tubos Múltiplos e o emprego de desinibidores bacterianos, determinou-se a Intensidade da Atividade de Inibição

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18

Tian-YouLiao and 廖天佑. "The modulating effects of rottlerin on psychostimulant-induced conditioned place preference." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/76401112620904555353.

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碩士<br>國立成功大學<br>行為醫學研究所<br>103<br>Three cocaine (10 mg/kg/conditioning, COC)- and methamphetamine (1 mg/kg/conditioning, MA)-place conditionings reliably established the drug-induced conditioned place preference (CPP) in 8-week-old male C57BL/6 mice. An intra-peritoneal rottlerin injection (5 mg/kg) at least 24 hrs prior to the first COC- and MA-place conditioning prevented the establishment of COC and MA-induced CPP. Following the establishment of the COC- and MA-induced CPP, three consecutive daily saline-place conditionings were used to extinguish mouse CPP performance. A single rottlerin i

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19

Ya-Fan, Liao, and 廖雅芳. "Human ornithine decarboxylase prevents apoptosis by rottlerin in human leukemia HL60 cells." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/77473494285300889940.

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碩士<br>中山醫學大學<br>免疫學研究所<br>91<br>Ornithine decarboxylase (ODC), a rate-determining enzyme of the polyamine biosynthetic pathway, is involved in the control of cell cycle, differentiation, cell growth and apoptosis. Previous studies described that protein kinase Cd (PKCd) regulates ODC activity. In this thesis, human leukemia cell line, HL60 cell, was used for the treatment with a specific PKCd inhibitor, rottlerin, to measure the effects on cell growth. Our data are showed that apoptosis parameters including DNA fragmentation, nuclear morphological change and sub-G1 fraction, appeared after

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20

Ming-HengHsiung and 熊明珩. "Involvement of different signaling pathways in mouse hippocampus in the modulatory effects of rottlerin and MK-801 on inhibitory avoidance memory." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/atbmfe.

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21

Nevělíková, Leona. "Exprese PKC alfa v myokardu potkana adaptovaného na/ hronickou hypoxii: vliv chelerythrinu a rottlerinu." Master's thesis, 2006. http://www.nusl.cz/ntk/nusl-373671.

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22

Rottler, Jessica [Verfasser]. "Lebensalter und endotheliale Dysfunktion: Veränderungen funktioneller, struktureller und biochemischer Kenngrößen der Endothelfunktion / vorgelegt von Jessica Rottler." 2005. http://d-nb.info/990489965/34.

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