Academic literature on the topic 'RSC complex'

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Journal articles on the topic "RSC complex"

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Mao, Steve. "The architecture of the RSC complex." Science 366, no. 6467 (2019): 833.3–833. http://dx.doi.org/10.1126/science.366.6467.833-c.

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Ye, Youpi, Hao Wu, Kangjing Chen, et al. "Structure of the RSC complex bound to the nucleosome." Science 366, no. 6467 (2019): 838–43. http://dx.doi.org/10.1126/science.aay0033.

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The RSC complex remodels chromatin structure and regulates gene transcription. We used cryo–electron microscopy to determine the structure of yeast RSC bound to the nucleosome. RSC is delineated into the adenosine triphosphatase motor, the actin-related protein module, and the substrate recruitment module (SRM). RSC binds the nucleosome mainly through the motor, with the auxiliary subunit Sfh1 engaging the H2A-H2B acidic patch to enable nucleosome ejection. SRM is organized into three substrate-binding lobes poised to bind their respective nucleosomal epitopes. The relative orientations of the
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Cairns, Bradley R., Yahli Lorch, Yang Li, et al. "RSC, an Essential, Abundant Chromatin-Remodeling Complex." Cell 87, no. 7 (1996): 1249–60. http://dx.doi.org/10.1016/s0092-8674(00)81820-6.

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Romeo, Martin J., Melinda L. Angus-Hill, Andrew K. Sobering, Yoshiaki Kamada, Bradley R. Cairns, and David E. Levin. "HTL1 Encodes a Novel Factor That Interacts with the RSC Chromatin Remodeling Complex in Saccharomyces cerevisiae." Molecular and Cellular Biology 22, no. 23 (2002): 8165–74. http://dx.doi.org/10.1128/mcb.22.23.8165-8174.2002.

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ABSTRACT RSC is an essential chromatin remodeling complex in Saccharomyces cerevisiae that performs central roles in transcriptional regulation and cell cycle progression. Here we identify Htl1 as a novel factor that associates with the RSC complex both physically and functionally. We isolated HTL1 through a genetic screen for mutants that displayed additive growth defects with a conditional mutation in the protein kinase C gene (PKC1), which has been suggested through genetic connections to interact functionally with RSC. Several lines of evidence connect HTL1 to RSC function. First, an htl1Δ
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Asturias, F. J., W. H. Chung, R. D. Kornberg, and Y. Lorch. "Structural analysis of the RSC chromatin-remodeling complex." Proceedings of the National Academy of Sciences 99, no. 21 (2002): 13477–80. http://dx.doi.org/10.1073/pnas.162504299.

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Soutourina, Julie, Véronique Bordas-Le Floch, Gabrielle Gendrel, et al. "Rsc4 Connects the Chromatin Remodeler RSC to RNA Polymerases." Molecular and Cellular Biology 26, no. 13 (2006): 4920–33. http://dx.doi.org/10.1128/mcb.00415-06.

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ABSTRACT RSC is an essential, multisubunit chromatin remodeling complex. We show here that the Rsc4 subunit of RSC interacted via its C terminus with Rpb5, a conserved subunit shared by all three nuclear RNA polymerases (Pol). Furthermore, the RSC complex coimmunoprecipitated with all three RNA polymerases. Mutations in the C terminus of Rsc4 conferred a thermosensitive phenotype and the loss of interaction with Rpb5. Certain thermosensitive rpb5 mutations were lethal in combination with an rsc4 mutation, supporting the physiological significance of the interaction. Pol II transcription of ca.
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Hsu, Jing-mei, Jian Huang, Pamela B. Meluh, and Brehon C. Laurent. "The Yeast RSC Chromatin-Remodeling Complex Is Required for Kinetochore Function in Chromosome Segregation." Molecular and Cellular Biology 23, no. 9 (2003): 3202–15. http://dx.doi.org/10.1128/mcb.23.9.3202-3215.2003.

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ABSTRACT The accurate segregation of chromosomes requires the kinetochore, a complex protein machine that assembles onto centromeric DNA to mediate attachment of replicated sister chromatids to the mitotic spindle apparatus. This study reveals an important role for the yeast RSC ATP-dependent chromatin-remodeling complex at the kinetochore in chromosome transmission. Mutations in genes encoding two core subunits of RSC, the ATPase Sth1p and the Snf5p homolog Sfh1p, interact genetically with mutations in genes encoding kinetochore proteins and with a mutation in centromeric DNA. RSC also intera
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Lia, Giuseppe, Elise Praly, Helder Ferreira, et al. "Direct Observation of DNA Distortion by the RSC Complex." Molecular Cell 21, no. 3 (2006): 417–25. http://dx.doi.org/10.1016/j.molcel.2005.12.013.

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Shim, Eun Yong, Jia-Lin Ma, Ji-Hyun Oum, Yvonne Yanez, and Sang Eun Lee. "The Yeast Chromatin Remodeler RSC Complex Facilitates End Joining Repair of DNA Double-Strand Breaks." Molecular and Cellular Biology 25, no. 10 (2005): 3934–44. http://dx.doi.org/10.1128/mcb.25.10.3934-3944.2005.

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ABSTRACT Repair of chromosome double-strand breaks (DSBs) is central to cell survival and genome integrity. Nonhomologous end joining (NHEJ) is the major cellular repair pathway that eliminates chromosome DSBs. Here we report our genetic screen that identified Rsc8 and Rsc30, subunits of the Saccharomyces cerevisiae chromatin remodeling complex RSC, as novel NHEJ factors. Deletion of RSC30 gene or the C-terminal truncation of RSC8 impairs NHEJ of a chromosome DSB created by HO endonuclease in vivo. rsc30Δ maintains a robust level of homologous recombination and the damage-induced cell cycle ch
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Sing, Tina L., Minnie P. Hung, Shinsuke Ohnuki, et al. "The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion." Journal of Cell Biology 217, no. 7 (2018): 2445–62. http://dx.doi.org/10.1083/jcb.201709009.

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Ploidy is tightly regulated in eukaryotic cells and is critical for cell function and survival. Cells coordinate multiple pathways to ensure replicated DNA is segregated accurately to prevent abnormal changes in chromosome number. In this study, we characterize an unanticipated role for the Saccharomyces cerevisiae “remodels the structure of chromatin” (RSC) complex in ploidy maintenance. We show that deletion of any of six nonessential RSC genes causes a rapid transition from haploid to diploid DNA content because of nondisjunction events. Diploidization is accompanied by diagnostic changes i
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Dissertations / Theses on the topic "RSC complex"

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GALATI, ELENA. "Yeast response to prolonged activation of the spindle assembly checkpoint." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/19557.

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Faithful chromosome segregation during mitosis is fundamental for cell viability and genome stability. For a correct division, all kinetochores must be attached to the mitotic spindle and cohesion must be timely removed. Anaphase is triggered by the Anaphase Promoting Complex bound to its regulatory subunit Cdc20 (APC-Cdc20) that polyubiquitylates securin (Pds1 in budding yeast), whose role is to maintain inactive the protease separase (Esp1 in budding yeast) until anaphase onset. Once active, separase cleaves cohesin, thus triggering sister chromatid separation. Separase also promotes cyclinB
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Chen, Wei, Jianfeng Zhang, John Mack, et al. "Corrole–BODIPY conjugates: enhancing the fluorescence and phosphorescence of the corrole complex via efficient through bond energy transfer." Royal Society of Chemistry, 2015. http://hdl.handle.net/10962/d1020277.

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New corrole–BODIPY conjugates have been synthesized in high yield under mild conditions. Upon excitation at the absorption maximum of the BODIPY antenna chromophore, the fluorescence intensity of the free base corrole–BODIPY conjugate increases by ca. 300%, and significant phosphorescence intensity is observed for the iridium(III) complex of the conjugate, while almost no phosphorescence is observed for the parent iridium(III) corrole, due to through-bond energy transfer from the BODIPY antenna-chromophore to the corrole core.<br>Original publication is available at http://dx.doi.org/10.1039/c
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Jain, Neha [Verfasser], Stefan [Akademischer Betreuer] Raunser, and Daniel [Gutachter] Summerer. "Role of histone modifications in the recruitment of remodeling complex RSC and lysine deacetylase Hst2 to chromatin / Neha Jain ; Gutachter: Daniel Summerer ; Betreuer: Stefan Raunser." Dortmund : Universitätsbibliothek Dortmund, 2020. http://d-nb.info/1230628681/34.

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Malicki, Marek [Verfasser], Christian [Akademischer Betreuer] Hammann, Christian [Gutachter] Hammann, Thomas [Gutachter] Winckler, and Matthias [Gutachter] Ullrich. "The Retrotransposon Silencing Complex (RSC) is a key repressor of retrotransposons in Dictyostelium discoideum / Marek Malicki ; Gutachter: Christian Hammann, Thomas Winckler, Matthias Ullrich ; Betreuer: Christian Hammann." Bremen : IRC-Library, Information Resource Center der Jacobs University Bremen, 2017. http://d-nb.info/1163109398/34.

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Deforzh, Evgeny. "Le complexe IMP3 protège ses ARNm cibles de la répression traductionnelle dépendante de Argonaute/GW182/miRNA." Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS203/document.

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Les protéines se liant à l’ARN de la famille IMP sont les protéines oncofoetales conservées, qui régulent le transport, la stabilité et la traduction de plusieurs ARNm cibles. Les IMPs sont impliqués dans la tumorigenèse et dans le développement embryonnaire par le contrôle de la prolifération cellulaire, la différenciation, la migration, la polarisation et d`autres processus cellulaires. IMP-3 est difficilement détectable dans des tissus adultes normaux, mais il est surexprimé dans les nombreux cancers, où il a été caractérisé comme un marqueur d’agressivité et de la croissance tumorale rapid
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Gomes, Júnior Rafael Araújo. "Efeitos de compostos naturais, sintéticos e da fototerapia antifúngica sobre Candida tropicalis resistente ao fluconazol." Centro de Pesquisas Gonçalo Moniz, 2014. https://www.arca.fiocruz.br/handle/icict/9954.

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Submitted by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2015-04-10T17:04:35Z No. of bitstreams: 1 Rafael AraujoGomes Junior Efeitos....pdf: 34966477 bytes, checksum: 15df6dc2a7def6eca56bbb84930c6ae3 (MD5)<br>Approved for entry into archive by Ana Maria Fiscina Sampaio (fiscina@bahia.fiocruz.br) on 2015-04-10T17:04:46Z (GMT) No. of bitstreams: 1 Rafael AraujoGomes Junior Efeitos....pdf: 34966477 bytes, checksum: 15df6dc2a7def6eca56bbb84930c6ae3 (MD5)<br>Made available in DSpace on 2015-04-10T17:04:46Z (GMT). No. of bitstreams: 1 Rafael AraujoGomes Junior Efeitos....pdf: 34966477 by
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Bordas-Le, Floch Véronique. "Remodelage de la chromatine : étude d'un mutant du complexe RSC chez la levure Saccharomyces cerevisiae." Phd thesis, Paris, Institut national d'agronomie de Paris Grignon, 2002. http://www.theses.fr/2002INAP0031.

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Le complexe RSC est un des facteurs de remodelage de la chromatine capables de lever la barrière nucléosomale notamment lors de la transcription. Ce processus est effectué chez les eucaryotes par trois ARN polymérases (pol). Nous avons montré que le complexe RSC interagit avec les pol I et III. La protéine Rsc4 interagit par son domaine C-terminal avec la protéine ABC27, commune aux trois ARN polymérases. Nous avons isolé une mutation de la sous-unité Rsc4 qui abolit cette interaction. Les profils d'expression génomiques, établis par puces à ADN, ont permis de caractériser ses effets sur la tr
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Tomida, Junya. "DNA damage induced ubiquitylation of RFC2 subunit of RFC complex." Kyoto University, 2008. http://hdl.handle.net/2433/135870.

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Kim, Jiyoung. "Functional analysis of RFC and RFC-like complexes in fission yeast." Thesis, University of Edinburgh, 2005. http://hdl.handle.net/1842/12375.

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RFC plays an essential role in DNA replication by loading the sliding clamp PCNA onto DNA in order to tether DNA polymerase δ to DNA. RFC consists of five subunits, one large subunit and four small subunits. The large subunit of RFC contains an extended C-­terminal domain that is not present in the small subunits and whose function remains unknown. In addition to RFC, eukaryotic cells contain two more putative PCNA loaders known as RLCs. These other PCNA loaders have similar structures to RFC and contains the RFC small subunits, however the large subunit is replaced with a different protein, e
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Litvin, Justin M. "Determining the Diagnostic Accuracy of and Interpretation Guidelines for the Complex Trauma Inventory [CTI]." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1609084/.

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The work group in charge of editing the trauma disorders in the upcoming edition of the International Classification of Diseases (ICD-11) made several changes to the trauma criteria. Specifically, they simplified the criteria for posttraumatic stress disorder (PTSD) and added a new trauma disorder called complex PTSD (CPTSD). To assess the new and newly defined trauma disorders, Litvin, Kaminski and Riggs developed a self-report trauma measure called the Complex Trauma Inventory (CTI). Although the reliability and validity of the CTI has been supported, no empirically-derived cutoff scores exi
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Books on the topic "RSC complex"

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Razavet, Jean-Claude. De Freud à Lacan: Du roc de la castration au roc de la structure. De Boeck Université, 2000.

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Razavet, Jean-Claude. De Freud à Lacan: Du roc de la castration au roc de la structure. De Boeck, 2000.

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Service, Canadian Security Intelligence, and Service canadien du renseignement de sécurité., eds. Weapons proliferation and the military: Industrial complex of the PRC = : La prolifération des armes et le complexe militaro-industriel de la RPC. Canadian Security Intelligence Service =, 2003.

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Hussain, S. Jaffer (Syed Jaffer) and ebrary Inc, eds. Oracle 11g R1/R2 real application clusters essentials: Design, implement, and support complex Oracle 11g RAC environments for real-world deployments. Packt Enterprise Pub., 2011.

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Deleuze, Gilles. Anti-Oedipus: Capitalism and schizophrenia. Continuum, 2000.

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Deleuze, Gilles. Anti-Oedipus: Capitalism and schizophrenia. Continuum, 2004.

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Deleuze, Gilles. Anti-Oedipus: Capitalism and Schizophrenia. Continuum Publishing Group, 2004.

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Deleuze, Gilles. Deleuze and Guattari's Anti-Oedipus: Introduction to schizoanalysis. Routledge, 1999.

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Allison, John P. Apartment Complex Recycling Guide (Rmc Order No 1014). RMC Publishing Group, 1992.

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Lichtenberg, Drew, and Deborah C. Payne. Shakespeare in the Theatre: Shakespeare Theatre Company. Bloomsbury Publishing Plc, 2024. http://dx.doi.org/10.5040/9781350352674.

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Co-authored by the resident dramaturg at Shakespeare Theatre Company and a long-time scholarly consultant, this book chronicles how a small repertory troupe at the Folger Theatre on Capitol Hill became an internationally renowned company performing in a lavish, multi-venue performing arts centre in downtown Washington, D.C. The artistic vision and business acumen of Michael Kahn, the founding Artistic Director, largely catalyzed this transformation, but so too did the forces of neoliberalism and, more recently, globalization and new media. Accordingly,Shakespeare in the Theatre: Shakespeare Th
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Book chapters on the topic "RSC complex"

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Prasad, Priya. "Loss of Function of Sth1, The Catalytic Component of RSC (Remodel the Structure of Chromatin) Complex Grossly Alter the Chromatin Architecture." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_17.

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AbstractChromatin architecture has a profound effect on the gene expression in eukaryotes. It is constantly modulated in the cells in response to different stress condition and during the normal physiological process in the cell. The chromatin is also modulated during the cell growth and division, where several proteins involved during the cell cycle are synthesized, and hence the gene expression profile and chromatin state of an actively dividing cell differ from that of a resting cell in G0 state. Candida albicans, which is a harmless commensal in human host and an opportunistic fungal patho
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Müller-Schloer, Christian, and Ernst Schmitter. "RISC — Compiler." In RISC-Workstation-Architekturen. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-58238-7_5.

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King, Andrew D., Nataša Pržulj, and Igor Jurisica. "Protein Complex Prediction with RNSC." In Bacterial Molecular Networks. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-61779-361-5_16.

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Zhang, Yan. "RNA-induced Silencing Complex (RISC)." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_329.

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Hussain, Syed Jaffar, Tariq Farooq, Riyaj Shamsudeen, and Kai Yu. "Managing and Optimizing a Complex RAC Environment." In Expert Oracle RAC 12c. Apress, 2013. http://dx.doi.org/10.1007/978-1-4302-5045-6_7.

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Chow, Paul. "The Compiler System." In The MIPS-X RISC Microprocessor. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-6762-9_3.

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Ascione, Francesco, and Howard D. Routman. "Severe Glenoid Erosion (B2, B3, C, E2, E3) Treated with RSA." In Complex and Revision Shoulder Arthroplasty. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-02756-8_5.

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Kroha, Petr. "Code generation for a RISC machine." In Compiler Compilers and High Speed Compilation. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/3-540-51364-7_16.

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Hong, Hoon. "RISC-CLP(CF) constraint logic programming over complex functions." In Logic Programming and Automated Reasoning. Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/3-540-58216-9_32.

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Burkova, Svetlana, Evgeniia Khristoforova, and Vadim Kimmelman. "Chapter 4. Syntactic functions of nonmanuals in Russian Sign Language." In Advances in Sign Language Corpus Linguistics. John Benjamins Publishing Company, 2023. http://dx.doi.org/10.1075/scl.108.04bur.

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This chapter presents the Russian Sign Language (RSL) Corpus and demonstrates its capabilities as a research tool by summarizing three corpus-based studies primarily focused on syntactic functions of nonmanual markers. The first study considers question marking in regular wh-questions and in question-answer pairs. It shows that the two constructions have very different nonmanual markers. The second study analyzes marking of topics in RSL, and shows that nonmanual markers of topics are typologically common, but are infrequent in naturalistic corpus data. The third study investigates conditional
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Conference papers on the topic "RSC complex"

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Zhao, Yuzheng, Bin Deng, Xiaoqiang Hua, and Hongqiang Wang. "Terahertz near-field RCS analysis of complex aircraft targets." In Terahertz Technology and Applications, edited by Juncheng Cao, Hongqiang Wang, Yiming Zhu, and Chao Zhang. SPIE, 2024. https://doi.org/10.1117/12.3046190.

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Wei, Yulun, Boguang Yang, Tao Hong, Baozhu Li, and Wen Jiang. "A Complex Target RCS Inversion Technique Based on Scattering Centers Extraction." In 2024 International Conference on Microwave and Millimeter Wave Technology (ICMMT). IEEE, 2024. http://dx.doi.org/10.1109/icmmt61774.2024.10671984.

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Kasahara, Isaac, Shubham Agrawal, Selim Engin, Nikhil Chavan-Dafle, Shuran Song, and Volkan Isler. "RIC: Rotate-Inpaint-Complete for Generalizable Scene Reconstruction." In 2024 IEEE International Conference on Robotics and Automation (ICRA). IEEE, 2024. http://dx.doi.org/10.1109/icra57147.2024.10611694.

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Ma, Yonglong, Weizhong Han, and Yingxiang Li. "Research on Lightning Target Detection in Complex Scenes Based on RCC-YOLOv7." In 2024 IEEE 7th Information Technology, Networking, Electronic and Automation Control Conference (ITNEC). IEEE, 2024. http://dx.doi.org/10.1109/itnec60942.2024.10733056.

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Ryan, Victoria, Hemant Thurumella, Nick D’Arcy-Evans, et al. "Utilizing Computational Fluid Dynamics to Estimate Drift Extent-from Aerial Spraying of Dispersants." In Offshore Technology Conference. OTC, 2022. http://dx.doi.org/10.4043/31826-ms.

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Abstract Aerial application of dispersants are an effective means of responding to oil spills in coastal waters and the deeper waters of the Outer Continental Shelf or Gulf of Mexico. To ensure the safety of responders and nearby wildlife, a buffer area is put in place around the spilled oil to be treated, within which spraying operations are conducted. In 2015, a research project was initiated to develop a prototype Decision Support Tool (DST) designed specifically for estimating the spray drift during the aerial application of dispersants on an oil spill. In 2019, an initiative was undertake
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Ryan, Victoria, Hemant Thurumella, Nick D’Arcy-Evans, et al. "Utilizing Computational Fluid Dynamics to Estimate Drift Extent-from Aerial Spraying of Dispersants." In Offshore Technology Conference. OTC, 2022. http://dx.doi.org/10.4043/31826-ms.

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Abstract Aerial application of dispersants are an effective means of responding to oil spills in coastal waters and the deeper waters of the Outer Continental Shelf or Gulf of Mexico. To ensure the safety of responders and nearby wildlife, a buffer area is put in place around the spilled oil to be treated, within which spraying operations are conducted. In 2015, a research project was initiated to develop a prototype Decision Support Tool (DST) designed specifically for estimating the spray drift during the aerial application of dispersants on an oil spill. In 2019, an initiative was undertake
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Pruyn, Jeroen. "An Evaluation of Suitable Methods to Deal with Deep Uncertainty Caused by the Energy Transition in Ship Design." In SNAME 14th International Marine Design Conference. SNAME, 2022. http://dx.doi.org/10.5957/imdc-2022-252.

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The maritime industry is transitioning toward zero emission. To ensure compliance with future emission reduction regulations, many different alternative fuels and technology options are being investigated and evaluated. However, as these are ongoing developments, this results in varying and changing data on the performance and requirements of options. On top of that, while regulatory ambitions are aiming for increasingly larger reductions of Green House Gases (GHG) and other harmful substances, the level and details of the future regulations are unknown and subject to ongoing scientific and so
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Giuliani, Fabrice, Andrea Hofer, Nina Paulitsch, and Bugra Akin. "Recursive Sequential Combustion Using Multiple Discrete Sectors." In ASME Turbo Expo 2023: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/gt2023-102889.

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Abstract Recursive Sequential Combustion (RSC, introduced in paper GT2021-59592) is a new concept that maximises the interaction between burned gases and fresh reactants. The novelty compared to other concepts of flue gas recirculation in gas turbines is that this interaction is solely driven by the flow dynamics in the combustor. It consists of a novel inlet/outlet arrangement and an advanced flow design, which avoids complex extraction, reconditioning and re-injection of flue gases. The key feature is the burner arrangement which places the flames one after the other in a closed loop, mainta
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Crisanti, A. "Configurational entropy and the one-step RSB scenario in glasses." In Disordered and complex systems. AIP, 2001. http://dx.doi.org/10.1063/1.1358167.

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Tian, Luo Hong. "Bidirectional Extreme Convergency Methods (BECM) to Identify the Mobility Regions of the RSSR Mechanism." In ASME 1992 Design Technical Conferences. American Society of Mechanical Engineers, 1992. http://dx.doi.org/10.1115/detc1992-0374.

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Abstract The BECM are proposed to classify spatial four-link mechanisms according to groups such as crank-rocker, double-rocker and double-crank (drag link). The BECM can determine the feasible regions and number of the extreme values exactly and solve them simply without complex derivation and calcultion. The paper concerns itself mainly with the RSSR linkage but it can be applied also to other types such as RSSP, RSCP, RSCR etc. The method is very simple and the geometric concept is very clear. Although the graphical methods is mainly introduced in this paper, certainly, it can also be coded
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Reports on the topic "RSC complex"

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Shujaa, Asaad Suliman, and Qasem Almulihi. The efficacy and safety of ketamine in treating refractory and super-refractory status epilepticus in pediatric and adult populations, A systemic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.11.0011.

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Review question / Objective: This study is to assess the efficacy and safety of ketamine in treating refractory and super-refractory status epilepticus in pediatric and adult populations. Rationale: Refractory status epilepticus (RSE) is either generalized or complex partial status epilepticus (SE) that fails to respond to first and second-line therapies. Super refractory status epilepticus (SRSE) is SE that remains unresponsive despite 24 hours of therapy with general anesthesia [1, 2]. Both RSE and SRSE pose significant challenges for the managing intensivist. There exists a race against tim
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Amela, R., R. Badia, S. Böhm, R. Tosi, C. Soriano, and R. Rossi. D4.2 Profiling report of the partner’s tools, complete with performance suggestions. Scipedia, 2021. http://dx.doi.org/10.23967/exaqute.2021.2.023.

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This deliverable focuses on the proling activities developed in the project with the partner's applications. To perform this proling activities, a couple of benchmarks were dened in collaboration with WP5. The rst benchmark is an embarrassingly parallel benchmark that performs a read and then multiple writes of the same object, with the objective of stressing the memory and storage systems and evaluate the overhead when these reads and writes are performed in parallel. A second benchmark is dened based on the Continuation Multi Level Monte Carlo (C-MLMC) algorithm. While this algorithm is norm
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Richards, John, Melisa Nallar, Christina Rinaudo, et al. RISC TAMER Framework : Resilient Installation Support Against Compound Threats Analysis and Mitigation for Equipment and Resources Framework. Engineer Research and Development Center (U.S.), 2024. http://dx.doi.org/10.21079/11681/48073.

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Every day, decision-makers must allocate resources based on the best available information at the time. Military installations face a variety of threats which challenge sustained functionality of their supporting and supported deployable systems. Considering the compounding and interdependent impacts of the threats, both specified (what is known) and unspecified (what is not known) and the investments needed to address these threats adds value to the decision-making process. Current risk management practices are generally evaluated via scenario analyses that do not consider compound threats, r
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Kirchhoff, Helmut, and Ziv Reich. Protection of the photosynthetic apparatus during desiccation in resurrection plants. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7699861.bard.

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In this project, we studied the photosynthetic apparatus during dehydration and rehydration of the homoiochlorophyllous resurrection plant Craterostigmapumilum (retains most of the photosynthetic components during desiccation). Resurrection plants have the remarkable capability to withstand desiccation, being able to revive after prolonged severe water deficit in a few days upon rehydration. Homoiochlorophyllous resurrection plants are very efficient in protecting the photosynthetic machinery against damage by reactive oxygen production under drought. The main purpose of this BARD project was
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Marchais, Gauthier, Sweta Gupta, and Cyril Owen Brandt. Améliorer l’accès à l’éducation des filles marginalisées dans les zones de conflit. Institute of Development Studies, 2021. http://dx.doi.org/10.19088/ids.2021.060.

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Une grande partie des enfants non scolarisés dans le monde vivent dans des zones de conflit. Un des principaux défis dans l’élimination des obstacles à l’instruction des filles marginalisées dans ces contextes réside dans la compréhension des formes multiples et croisées de la marginalisation et des changements dans leurs dynamiques au cours des conflits violents. Les recherches menées en République démocratique du Congo (RDC) dans le cadre du projet d’éducation REALISE identifient des éléments clés à prendre en compte dans les programmes d’éducation destinés aux filles marginalisées dans les
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Hrynick, Tabitha, Godefroid Muzalia, and Myfanwy James. Considérations clés : Communication des risques et engagement communautaire pour la vaccination contre la mpox dans l’est de la République démocratique du Congo. Institute of Development Studies, 2024. http://dx.doi.org/10.19088/sshap.2024.032.

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Cette note stratégique présente des considérations sociales et politiques pour la conception et la mise en œuvre de stratégies de communication des risques et d’engagement communautaire (CREC) liées à la vaccination contre la mpox en République démocratique du Congo (RDC). Une flambée épidémique de mpox (clade I) à l’échelle nationale a été déclarée fin 2022 et touche désormais 23 de ses 26 provinces. En particulier, la flambée épidémique est caractérisée par une transmission interhumaine généralisée, contrairement aux précédentes, qui impliquaient principalement un contact animal-humain. Tand
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KellerLynn, Katie. Redwood National and State Parks: Geologic resources inventory report. National Park Service, 2021. http://dx.doi.org/10.36967/nrr-2287676.

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Comprehensive park management to fulfill the NPS mission requires an accurate inventory of the geologic features of a park unit, but Comprehensive park management to fulfill the NPS mission requires an accurate inventory of the geologic features of a park unit, but park managers may not have the needed information, geologic expertise, or means to complete such an undertaking; therefore, the Geologic Resources Inventory (GRI) provides information and resources to help park managers make decisions for visitor safety, planning and protection of infrastructure, and preservation of natural and cult
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Badia, R., J. Ejarque, S. Böhm, C. Soriano, and R. Rossi. D4.4 API and runtime (complete with documentation and basic unit testing) for IO employing fast local storage. Scipedia, 2021. http://dx.doi.org/10.23967/exaqute.2021.9.001.

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This deliverable presents the activities performed on the ExaQUte project task 4.5 Development of interface to fast local storage. The activities have been focused in two aspects: reduction of the storage space used by applications and design and implementation of an interface that optimizes the use of fast local storage by MPI simulations involved in the project applications. In the rst case, for one of the environments involved in the project (PyCOMPSs) the default behavior is to keep all intermediate les until the end of the execution, in case these les are reused later by any additional ta
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Marchais, Gauthier, Jean-Benoît Falisse, Samuel Matabishi, and Deborah West. Note de synthèse : Projet de recherche BRiCE RDC et Niger: Bien-être des enseignants et qualité de l’enseignement dans les contextes fragiles et touchés par des conflits. Institute of Development Studies, 2025. https://doi.org/10.19088/ids.2024.015.

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Les enseignants et les éducateurs qui travaillent dans des contextes fragiles et touchés par des conflits sont à l'avant-garde de crises complexes qui affectent les écoles dans lesquelles ils travaillent ainsi que leur vie personnelle, et sont confrontés à des conditions de travail extrêmement difficiles. Au cours des deux dernières années, la pandémie de Covid-19 a exacerbé les défis auxquels ils sont confrontés dans des secteurs éducatifs souvent marqués par un sous-financement structurel et de fortes inégalités.Pourtant, ils continuent d’accomplir leur travail au mieux de leurs capacités et
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Rans, Richard. PR-352-16603-Z03 Multi-Vendor USM Test and Calibration Database with Common Diagnostics. Pipeline Research Council International, Inc. (PRCI), 2020. http://dx.doi.org/10.55274/r0011657.

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Data collection protocols and a common database have been developed to ensure complete and consistent collection of USM calibration data, logs files and documentation of test piping layout. By using an Excel input table spreadsheet, with instructions on how to organize the collected data, users can easily input data from multiple types of ultrasonic meters. The database retains the original calibration and log file data and processes the test results into standardized velocity and speed of sound reports. This organization supports reporting the original meter specific log file data and diagnos
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