Academic literature on the topic 'Rubeole congenitale'

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Journal articles on the topic "Rubeole congenitale"

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Wulandari, Ratna, and Astrid Novita. "Alternatif Kebijakan dalam Upaya Peningkatan Minat Wanita Usia Subur Melakukan Imunisasi Campak dan Rubela." Jurnal Ilmiah Kebidanan Indonesia 9, no. 02 (July 16, 2019): 47–57. http://dx.doi.org/10.33221/jiki.v9i02.216.

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Imunisasi Campak dan Rubela pada Wanita Usia Subur (WUS) hingga saat ini masih menjadi kategori imunisasi lanjutan pilihan yang belum diwajibkan. Ibu hamil yang menderita Campak dan Rubela akan memiliki risiko tinggi janinnya mengalami kelainan bawaan pada bayi baru lahir atau yang dikenal dengan Congenital Rubella Syndrome (CRS). Di Puskesmas Kecamatan Pasar Minggu kunjungan WUS yang melakukan imunisasi Campak Rubela <100 kunjungan dengan 11 kejadian CRS pada Tahun 2017. Untuk itu perlu dilakukan penelitian yang bertujuan untuk menentukan identifikasi masalah, kriteria evaluasi, dan rumusan alternatif kebijakan dalam upaya meningkatkan minat WUS dalam melakukan imunisasi Campak Rubela. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Informan dalam penelitian ini meliputi Kepala Puskesmas sebagai Informan Kunci serta Tim Imunisasi Campak Rubela dan User sebagai informan pendukung. Pengumpulan data dilakukan dengan metode indepth interview. Hasil temuan masalah dalam penelitian ini antara lain ; belum ada data jumlah penderita campak dan rubella dewasa, belum ada upaya promotif untuk meningkatkan pengetahuan WUS tentang imunisasi Campak Rubela, belum ada anggaran untuk upaya promotif imunisasi Campak Rubela dewasa, dan kurangnya koordinasi antar unit kesehatan dalam memperkenalkan imunsasi Campak Rubela untuk WUS. Setelah dilakukan analisis dengan metode Urgency Strategy Growth (USG) dan Strenght Weight Opptunity Threat (SWOT), prioritas masalah yang terpilih adalah belum adanya upaya promotif imunisasi campak dan rubella untuk dewasa. Usulan alternatif rekomendasi kebijakan terpilih adalah penyusunan Standar Operasional Prosedur Upaya Promotif Kesehatan Imunisasi Campak Rubela untuk WUS, yang disusun dalam bentuk Standar Operasional Prosedur yang isinya meliputi acuan kegiatan, diagram alur dan anggaran biaya. Saran yang diberikan untuk lahan penelitian adalah segera disusun kebijakan untuk pemberian imunisasi Campak dan Rubela dengan prioritas sasarannya adalah WUS untuk mencegah kejadian CRS.
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Lim, G. H., S. L. Deeks, J. Fediurek, J. Gubbay, and N. S. Crowcroft. "Consignation de l'élimination de la rougeole, de la rubéole et de l'embryopathie rubéolique en Ontario : 2009-2012." Relevé des maladies transmissibles au Canada 40, no. 8 (April 17, 2014): 162–71. http://dx.doi.org/10.14745/ccdr.v40i08a01f.

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Tandililing, Lily Cahyani, Djatnika Setiabudi, and Nelly Amalia Risan. "Hubungan Jenis Kelamin, Usia Gestasi, dan Berat Badan Lahir dengan Sindrom Rubela Kongenital." Sari Pediatri 17, no. 4 (October 26, 2016): 302. http://dx.doi.org/10.14238/sp17.4.2015.302-6.

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Latar belakang. Sindrom rubela kongenital (SRK) masih merupakan masalah kesehatan di Indonesia. Berdasarkan penelitian terdahulu. faktor usia gestasi, berat badan lahir, dan jenis kelamin berhubungan dengan kasus confirmed sindrom rubela kongenital.Tujuan. Menentukan hubungan jenis kelamin, usia gestasi, dan berat badan lahir dengan kasus probable SRK.Metode. Penelitian observasional analitik dengan rancangan potong lintang. Data retrospektif diperoleh dari rekam medis pasien rawat inap dan rawat jalan usia <1 tahun periode 1 Januari 2008-31 Desember 2014, dengan kode diagnosis (ICD-10) meliputi congenital rubella syndrome, congenital heart disease, congenital cataract, sensorineural hearing loss, cerebral palsy, dan neonatal jaundice. Klasifikasi kasus SRK berdasarkan CDC 2009, yaitu suspected, probable, confirmed, dan infection only. Pemilihan subjek secara purposive sampling. Analisis statistik dilakukan dengan analisis bivariat dan regresi logistik untuk faktor dengan p<0,25 dengan Rasio Odds (RO) dan Interval Kepercayaan (IK) 95%.Hasil. Didapat 133 subjek klasifikasi SRK suspected (96), terdiri atas probable (29) dan confirmed (8). Mayoritas subjek laki-laki (58,6%), usia ibu 25-29 (48,9%) tahun, multipara (54,1%), dan tanpa riwayat vaksinasi rubela (100%). Hubungan bermakna didapatkan dalam analisis regresi logistik pada faktor jenis kelamin (p=0,002; OR 6,656; IK95% 2,046–21,657) dan berat badan lahir (p<0,001; OR 10,365; IK95% 2,839–37,834).Kesimpulan. Jenis kelamin dan berat badan lahir berhubungan dengan kasus probable SRK. Diperlukan penelitian prospektif untuk menentukan hubungan usia gestasi dengan kasus probable SRK.
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Kuzhiyil, Aslam Pala, Rajesh Thaliyil Veettil, Binci Charulatha, and Geeta M. Govindaraj. "Congenital Rubella Syndrome among Hospitalised Infants in South India - A Long Way to Go." Journal of Evidence Based Medicine and Healthcare 8, no. 10 (March 8, 2021): 551–55. http://dx.doi.org/10.18410/jebmh/2021/108.

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BACKGROUND The prevalence of rubella immunity in India is 55 % in pregnant women during the first 3 months of pregnancy and nearly 45 % of women are susceptible to congenital rubella syndrome. The exact epidemiology or actual burden of congenital rubella syndrome has not yet been assessed in the Indian population. In the run up to the target of controlling congenital rubella by 2020, there is added impetus to document congenital rubella syndrome cases, its clinical characteristics, interventions needed and psychosocial problems of infants and their parents, admitted with laboratory confirmed congenital rubella syndrome. METHODS A retrospective study based on hospital records was conducted between January 2016 and December 2017. Clinically confirmed cases not satisfying laboratory criteria for congenital rubella syndrome were excluded. In-depth interviews of mothers were conducted. RESULTS 16 infants with a positive IgM rubella antibody were included. Microcephaly was observed in 9 (56 %) babies. Ophthalmological manifestations were present in 12 (75 %) babies; of whom 9 (75 %) had cataract. Glaucoma occurred in 3 (18 %) babies and 2 (12.5 %) had salt and pepper retinopathy. Hearing impairment was detected in 8 (50 %) babies. Congenital heart disease was present in 15 (93.7 %) infants. Surgical interventions including cataract surgery, patent ductus arteriosus ligation and cochlear implantation were necessary in 14 babies. CONCLUSIONS Congenital rubella syndrome is still a significant problem and urgent measures are needed to increase immunisation coverage of the target population. Affected families endure a heavy physical and psychosocial burden, which should be addressed simultaneously. KEYWORDS Congenital Rubella Syndrome, Rubella Vaccination, Cataracts
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Multazam, Chaq El Chaq Zamzam, Mahrus A. Rahman, and Wiwin Retnowati. "Profile of Age and Sex of Congenital Rubella Syndrome Patients with Congenital Heart Disease." Health Notions 5, no. 3 (January 23, 2021): 100–103. http://dx.doi.org/10.33846/hn50306.

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Background: Rubella is an acute viral disease that often attacks vulnerable children and young adults throughout the world. Even though it only causes mild clinical illness, concern in the health world arises from its teratogenic potential resulting in congenital rubella syndrome (CRS). The most common abnormalities of CRS are hearing loss or deafness, eye defects and congenital heart defects. Purpose: To determine the profiles of age and sex in congenital rubella syndrome patients with congenital heart disease in Dr Soetomo Regional Public Hospital for the period of 2016-2018. Methods: This type of research was a descriptive study by collecting data on the age and sex in congenital rubella syndrome patients with congenital heart disease in Dr Soetomo Regional Public Hospital retrospectively through medical records of patients for the period of 2016-2018. Results: The most age group of congenital rubella syndrome patients with congenital heart disease in Dr Soetomo Regional Public Hospital for the period of 2016-2018 was the toddler (0-
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Matalia, Jyoti, and Sheetal Shirke. "Congenital Rubella." New England Journal of Medicine 375, no. 15 (October 13, 2016): 1468. http://dx.doi.org/10.1056/nejmicm1501815.

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HUSSAIN, MISS NAGEEN. "CONGENITAL RUBELLA SYNDROME." Professional Medical Journal 13, no. 01 (March 6, 2006): 11–16. http://dx.doi.org/10.29309/tpmj/2006.13.01.5047.

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Rubella is a major public health problem which is usually a mild rashillness in children and adults. However, its seriousness and public health importance stems from the ability of Rubellavirus to cross the placental barrier and infect fetal tissue, which may result in congenital rubella syndrome. Themechanism by which Rubella virus causes fetal damage is not well understood. Congenital rubella syndrome is anunder-recognized public health problem in Pakistan and can be reduced by vaccinating all seronegative women
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Andriatahina, Todisoa N., Lantonirina Ravaoarisoa, Andrianina H. Ranivoson, Vonintsoa L. Rahajamanana, Zina A. Randriananahirana, Jocelyn Andriamahita, Jean C. Andrianirinarison, and Annick L. Robinson. "Epidemio-clinical aspects of congenital rubella syndrome in Madagascar." International Journal of Research in Medical Sciences 8, no. 2 (January 27, 2020): 424. http://dx.doi.org/10.18203/2320-6012.ijrms20200031.

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Background: Congenital rubella syndrome is the first congenital defect preventable by vaccination. The purpose of this study was to provide basic information on the extent and epidemiology of congenital rubella syndrome in Madagascar.Methods: A retrospective and descriptive study from January 2013 to May 2019 was conducted in 8 hospitals in 2 provinces of Madagascar, Antananarivo and Toliara. The study included children who attended the services selected during the study period and who had the following conditions: children aged of 0 to 59 months, regardless of vaccination status, meeting the World Health Organization clinical criteria for congenital rubella syndrome with or without biological confirmation.Results: Of the 152,304 cases of children of all ages who visited or were hospitalized during the study period, 112 clinically confirmed cases of congenital rubella syndrome were identified. The age group 0 to 11 months involved 60 children (53.6%). Congenital heart disease was found in 83.0% of cases, mental backwardness in 43.7% and microcephaly in 26.8%. Twenty-three among (20.5%) them died. The death was due to cardiac diseases in 16 children.Conclusions: Findings confirm that the diagnosis of congenital rubella syndrome is underestimated in current pediatric practice in Madagascar. The introduction of the rubella vaccine in the Expanded Program on Immunization and the implementation of an effective and sustainable surveillance system for congenital rubella syndrome in the country is a proved effective tool for the prevention of this disease.
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Osman, Mahmoud M., Meryat T. Zakaria, Mutassem F. Alnofal, Sulafa A. Hamdoun, and Mohammed S. Alissa. "Congenital rubella syndrome: a case report." International Journal of Contemporary Pediatrics 7, no. 10 (September 21, 2020): 2054. http://dx.doi.org/10.18203/2349-3291.ijcp20204052.

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Currently, rubella virus infections are very rare in many countries, and may not be recognized promptly. However, congenital rubella syndrome still appears, often in infants of mothers coming from countries with suboptimal vaccination programs. We describe a case of CRS in a full-term baby girl born to a foreign mother who documented perinatal antibodies against rubella. The baby had the classical abnormalities seen in infants with CRS include congenital cardiac and ocular anomalies. The diagnosis was confirmed by positive rubella serology in both infant and mother. Vaccination is the only known prophylactic measure for congenital rubella syndrome.
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Spika, J. S., F. X. Hanon, S. Wassilak, R. G. Pebody, and N. Emiroglu. "Preventing congenital rubella infection in the European Region of WHO: 2010 target." Eurosurveillance 9, no. 4 (April 1, 2004): 3–4. http://dx.doi.org/10.2807/esm.09.04.00455-en.

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The World Health Organisation (WHO) Regional Office for Europe has recently published a strategic plan and surveillance guidelines for measles and congenital rubella infection. The strategy prioritises measles control activities but encourages the introduction of rubella vaccine when measles vaccine coverage has reached &gt;90 %; although, many western European countries with suboptimal measles vaccine coverage are already using the combined measles, mumps and rubella (MMR) vaccine. Women in these countries may have an especially high risk of having an infant with congenital rubella syndrome. WHO is seeking to improve the surveillance for rubella and congenital rubella syndrome as a means to obtain better information on the burden of these diseases and engage policy decision makers in the need to support the WHO European Region's strategies for rubella.
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Dissertations / Theses on the topic "Rubeole congenitale"

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Nieto, Jean-Pierre. "L'omnipraticien et la prevention de la rubeole congenitale." Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20267.

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Jacob, Sandrine. "Epidémiologie de la rubéole en France chez la femme enceinte et le nouveau-né." Paris 5, 1997. http://www.theses.fr/1997PA05P159.

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STAMM, DIDIER. "Pneumopathies interstitielles du syndrome tardif de la rubeole congenitale : evolution du taux des complexes immuns circulants : a propos de 2 observations." Lyon 1, 1988. http://www.theses.fr/1988LYO1M166.

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Stratton, Ellen Elizabeth. "Prevention of congenital rubella syndrome in Newfoundland." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27420.

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The Newfoundland Department of Health administers several rubella vaccination programs for the prevention of congenital rubella syndrome (CRS). This study examined the effectiveness of these programs by reviewing rubella susceptibility in the population at risk for CRS, assessing the predictive value of a rubella vaccination record, and evaluating the effectiveness of the postnatal rubella vaccination program.
From 1989 to 1993, rubella susceptibility in women aged 15 to 44 averaged 4.6% overall, but was significantly higher in women aged 15 to 19 years, averaging 14%. The positive predictive value of a rubella vaccination record was 92% overall, but it differed by type of vaccine product and vaccine viral strain; 99% for any monovalent rubella vaccine, compared to 81% for recipients of HPV-77 DE-5 strain MR (measles rubella) or MMR (measles mumps rubella) vaccine. The postnatal rubella vaccination program failed to provide testing for 13% of pregnant women in the province in 1992, and 10% of susceptible women in 1992 were not subsequently vaccinated.
These results suggest that women of childbearing age in Newfoundland remain at risk of having children with CRS. The rubella vaccination record is not adequate proof of immunity for some of these women, and the postnatal vaccination program requires some improvement in order to prevent cases of CRS in the future.
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Stratton, Ellen Elizabeth. "Prevention of congenital rubella syndrome in Newfoundland." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29795.pdf.

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Kanak, Alison Elizabeth. "Induction of Apoptosis by Rubella Virus Non-Structural Replicase and Rescue by Capsid." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/biology_theses/18.

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As a model for studying apoptosis associated with pathogenesis of congenital rubella syndrome, bicistronic rubella virus (RUBV) replicons expressing an antibiotic resistance gene in the presence (925-IN) or absence (IN-IN) of RUBV capsid protein (C) were constructed. Apoptosis was assessed by detection of caspase activation, chromatin fragmentation, and flow cytometry. 925-IN cells grew similarly to Vero, but IN-IN cells demonstrated caspase activation, chromatin fragmentation and cell cycle arrest. Whereas Vero cells transfected with P150 exhibited rapid apoptosis not detected in transfected Vero cells stably expressing C, neither exhibited cell cycle alterations, indicating a cell cycle stall not associated with apoptosis. Finally, two human epithelial cells, HEK293 and A549, transfected with P150 failed to exhibit apoptosis, indicating that while replicon-transfected Vero cells are useful for studying apoptosis and cell cycle arrest, the results are not applicable to other cell types.
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Cloete, Leendert J. "The molecular evolution and epidemiology of Rubella virus." Thesis, University of the Western Cape, 2014. http://hdl.handle.net/11394/4084.

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>Magister Scientiae - MSc
Despite widespread rubella virus (RV) vaccination programs, annually RV still causes severe congenital defects in an estimated 100,000 children globally. A concerted attempt to eradicate RV is currently underway and analytical tools to monitor the global decline of the last remaining RV lineages will be useful for assessing the effectiveness of this endeavour. Importantly, RV evolves rapidly enough that much of its epidemiological information might be inferable from RV genomic sequence data. Using BEASTv1.8.0, I analysed publically available RV sequence data to estimate genome-wide and gene-specific nucleotide substitution rates, to test whether the current estimates of RV substitution rates are representative of the entire RV genome. During these investigations, I specifically accounted for possible confounders of nucleotide substitution rate estimates, such as temporally biased sampling, sporadic recombination, and natural selection favouring either increased or decreased genetic diversity (estimated by the PARRIS and FUBAR methods) at nucleotide sites within RV nucleic acid secondary structures (predicted by the NASP method). I determined that RV nucleotide substitution rates range from 1.19×10-3 substitutions/site/year (in the E1 region) to 7.52×10-4 substitutions/site/year (in the P150 region). I found that these differences between nucleotide substitution rate estimates in various RV gene regions are largely attributable to temporal sampling biases, such that datasets containing a higher proportion of recently sampled sequences will tend to have inflated estimates of mean substitution rates. Although there exists little evidence of positive selection or natural genetic recombination in RV, I revealed that RV genomes possess extensive biologically functional nucleic acid secondary structures and that purifying selection acting to maintain these structures contributes substantially to variations in estimated nucleotide substitution rates across RV genomes. Although both temporal sampling biases and purifying selection favouring the conservation of RV nucleic acid secondary structures have an appreciable impact on substitution rate estimates, I find that these biases do not preclude the use of RV sequence data to date ancestral sequences and evaluate the associated RV phylodynamics. The combination of uniformly high substitution rates across the RV genome and strong temporal signal within the available sequence data enabled me to analyse the epidemiological and demographical dynamics of this virus during these attempts to eradicate it. By implementing a generalized linear model (GLM) and symmetrical model of discretized phylogeographic spread, I was able to identify several predictive variables of geographical RV spread and detect transmission linkages between distinct geographical regions. These results suggest that, in addition to strengthened vaccination strategies, there also needs to be an increased effort to educate people about the effects of vaccination and risks of RV infection.
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Sato, Helena Keico. ""Estudo dos efeitos da vacina contra rubéola sobre o produto da gestação de mulheres vacinadas durante campanha realizada no estado de São Paulo em 2001"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-12062006-112637/.

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O objetivo deste estudo é estimar o risco de infecção congênita pelo vírus da vacina contra rubéola e estimar o risco de ocorrência de aborto, baixo peso e prematuridade nas gestantes suscetíveis e imunes para rubéola identificando os fatores de risco associados a estes eventos. Embora não tenham havido manifestações clínicas compatíveis com SRC, observou-se uma ocorrência aumentada de baixo peso ao nascer e prematuridade entre os RN infectados quando comparados com as crianças não infectadas também nascidas de mães susceptíveis. No modelo final das análises utilizando a regressão logística multivariada, entretanto, a suscetibilidade para rubéola não esteve associada com a ocorrência de baixo peso e nem com prematuridade. Estes resultados sugerem que a recomendações de não vacinar gestantes para rubéola ainda deve ser mantida
The objective of this study is to evaluate the risk of congenital infection due to rubella vaccine virus and the occurrence of premature labor, miscarriage, and low birth weight in susceptible and immune pregnant women vaccinated during pregnancy, identifying the risk factors associated. We observe a high incidence of low birth weight and prematurity in the infected newborns, when compared with the children not infected, also born of susceptible mothers. In the final model of the logistic regression we didn't find association with rubella susceptibility and the predictors miscarriage, low birth weight and premature labor. These results suggest that the recommendations to not vaccinate pregnant women against rubella must be sustained
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Kashiwagi, Néa Miwa. ""Análise clínico-epidemiológica das gestantes inadvertidamente vacinadas contra a rubéola"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5137/tde-16102006-150543/.

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INTRODUÇÃO: Em 1999 e 2000, a ocorrência de surtos de rubéola, com maior acometimento entre adultos jovens, refletiu no aumento da síndrome da rubéola congênita. Como estratégia de controle da doença, foram realizadas campanhas de vacinação contra a rubéola em mulheres em idade fértil em vários Estados do País. Em razão das controvérsias existentes na literatura geradas quanto ao emprego da vacina de vírus vivos atenuados em gestantes, não se recomendou sua utilização durante a gravidez e até um mês após a aplicação da vacina. No entanto, 6.473 mulheres foram inadvertidamente vacinadas no Estado de São Paulo, sendo encaminhadas a serviços de referência para acompanhamento dessas gestações, dentre eles, o HCFMUSP. OBJETIVO: Este estudo buscou descrever as características clínicas e epidemiológicas das gestantes atendidas no HCFMUSP e obter os resultados dessas gestações. MÉTODO: Foi realizado um estudo epidemiológico descritivo, utilizando-se como fonte de dados as notificações das gestantes inadvertidamente vacinadas contra a rubéola e atendidas no HCFMUSP entre novembro de 2001 a dezembro de 2002. Para obter o desfecho das gestações, utilizou-se a base de dados dos nascidos vivos do Município de São Paulo (SINASC). RESULTADOS: No HCMFUSP, foram atendidas e notificadas 409 gestantes. Destas, 49,1% foram vacinadas no primeiro mês de gravidez e 26,2% engravidaram até um mês após a vacinação. Em relação a condição sorológica durante o pré-natal, 16,9% das gestantes apresentaram sorologia reagente para rubéola. Do relacionamento com a base de dados do SINASC, foram localizados os dados do parto de 63,3% das gestantes, sendo detectadas duas malformações congênitas no SINASC e um abortamento, porém, não se pode atribuir estes resultados à vacina, pois, as sorologias das mães não permitem determinar se estas mulheres eram realmente suscetíveis. CONSIDERAÇÕES FINAIS: O estudo apresentou o fluxo de informação estabelecido frente a um evento inusitado. Além disso, o uso de bases de dados secundárias contribuiu para o aprimoramento dos dados coletados, resultando na melhora da qualidade das informações. Os Núcleos de Epidemiologia Hospitalar são fundamentais na articulação entre a equipe assistencial e o Sistema de Vigilância e colaboram para discussão na padronização de Sistemas de Informação para permitir melhor integração entre as informações geradas pelos Serviços de Saúde.
INTRODUCTION: In the years 1999 and 2000, rubella outbreaks reaching mostly young adults resulted in an increased number of cases of Congenital Rubella Syndrome in Brazil. State Vaccination Campaigns aiming at women at childbearing age were promoted around the country to control the disease, recommending that vaccination of pregnant women should be avoided and pregnancy should be postponed for at least a month after vaccination. Despite the recommendations, 6.473 pregnant women were accidentally vaccinated in the State of São Paulo and therefore sent to reference obstetrical services for prenatal care. A study was conducted to describe the cases assisted at the University of São Paulo, School of Medicine, General Hospital and notified to Public Health and also to obtain information on the pregnancy outcomes. METHODS: This descriptive epidemiological study used notification by the Hospital Epidemiology Service as source of information on pregnant women accidentally vaccinated against rubella that received care from November 2001 to December 2002 at the School of Medicine, General Hospital. The City of São Paulo Newborn Database was searched for pregnancy outcomes. RESULTS: Among the 409 notified cases, 49,1% were women accidentally vaccinated during fist trimester of pregnancy and 26,2% women that became pregnant within less than a month after vaccination. Positive serological tests were found in 16,9% of women during prenatal care. Newborn data base search yielded pregnancy outcome for 63,3%. The findings of 2 cases of Congenital Rubella Syndrome and 1miscarriage cannot be surely attributed to vaccination because immediate previous immunization status was unknown. CONCLUSIONS: The study described the information flow established for an unexpected adverse event and the use of secondary data to improve quality of information. Hospital Epidemiology Services have a fundamental role in connecting health assisting professionals to Public Surveillance Systems and in setting standards for information generated by Health Assistance.
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Pedreira, Denise Araujo Lapa. "Rubéola na gestação: repercussões sobre o produto conceptual." Universidade de São Paulo, 1998. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-21062007-155741/.

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OBJETIVOS: Avaliar os efeitos da rubéola durante a gestação, sobre o feto, o recém-nascido e a criança. CASUÍSTICA E MÉTODO: Analisamos 35 gestantes com suspeita de rubéola que foram divididas em dois grupos. Grupo 1: 15 pacientes que apresentaram quadro clínico com comprovação sorológica. Grupo2: 20 pacientes com IgM positiva na rotina pré-natal, na ausência de quadro clínico. O seguimento ultrasonográfico mensal foi realizado em todas as pacientes e as do grupo 1 foram encaminhadas também para propedêutica invasiva. Foram também realizadas a ecocardiografia fetal e a Dopplervelocimetria. As placentas foram submetidas a exame anátomo-patológico. Os recém-nascidos vivos foram avaliados através de exame clínico e sorológico, além do potencial evocado auditivo, ultra-sonografia de crânio, fundo de olho e ecocardiografia pós-natal. RESULTADOS: No grupo 1: a infecção fetal ocorreu em 9 casos, sendo que o risco de transmissão vertical entre 2 a 14 semanas foi de 64,9%. A malformação ocorreu em 37,5% dos infectados. A ultrasonografia revelou crescimento intra-uterino retardado simétrico em todos os fetos infectados que atingiram o terceiro trimestre, tendo se iniciado, em média com 25,1 semanas. A cordocentese foi realizada em 9 pacientes e, todos os casos infectados, apresentavam IgM positiva e eritroblastose no sangue de cordão. A PCR no líquido amniótico foi positiva em todos os 3 casos em que ela foi realizada. 50% das placentas dos fetos infectados apresentava sinais sugestivos de infecção viral. A idade gestacional média do parto entre os infectados foi de 33,8 semanas e o peso médio ao nascimento foi 1365,6g.Todos os 6 nascidos-vivos infectados foram classificados como pequenos para a idade gestacional e apresentaram disacusia. A sobrevida entre os infectados, num seguimento pós-natal médio de 35,2 meses, foi de 62,5%. No grupo 2: a infecção não foi comprovada em nenhum dos recém-nascidos vivos, porém em um caso pudemos demonstrar a infecção congênita pelo vírus de Epstein-Barr. CONCLUSÕES: A transmissão vertical da rubéola no primeiro trimestre parece poder variar entre as populações, bem como a presença dos defeitos associados à infecção. Tanto o diagnóstico invasivo, como o ultrasonográfico apresentaram boa sensibilidade e especificidade. Pudemos estabelecer o padrão de crescimento fetal associado à infecção. A presença isolada de IgM positiva para rubéola na gestação não teve boa correlação com a presença de infecção neonatal, porém pode se associar à presença de outras infecções congênitas.
OBJECTIVES: Our aim was to analyse rubella effects on the fetus, new-born and child. MATERIAL AND METHODS: We analysed 35 patients with suspicious rubella during pregnancy. According to presence or absence of symptoms they were divided in two groups. Group 1: 15 patients presenting rash in which serology was positive. Grupo2: 20 symptomless patients found to have positive IgM during routine prenatal care. Monthly ultrasonographic evaluation was accomplished in all patients and in group 1 they were also offered prenatal invasive testing. Fetal echocardiography and Dopplers were performed. After birth, the placentas were submitted to pathological examination. The liveborn babies had clinical and serological examination. Auditory tests, brain scan, fundoscopy and postnatal echocardiography were also performed. RESULTS: In group 1: fetal infection occurred in 9 cases and vertical transmission between 2 to 14 weeks was 64,9%. Malformation was present in 37,5% of infected cases. Ultrasound revealed symmetrical intra-uterine growth retardation in all infected fetuses that reached the third trimester, and started around 25,1 weeks. Cordocentesis was accomplished in 9 cases and all the infected ones, presented positive IgM and erythroblastosis in cord blood. PCR in the amniotic fluid was positive in all 3 cases it was performed. 50% of the infected fetuses placentas presented signs of viral infection. The average gestacional age of delivery among infected cases was 33,8 weeks and medium birth weight was 1365,6g. All 6 liveborn infected babies were small for gestacional age and presented deafness. Survival among infected cases was 62,5%, medium follow-up was 35,2 months. In group 2: the infection was not demonstrated in any of neonates, although we could demonstrate a congenital infection caused by the Epstein-Barr virus. CONCLUSIONS: Vertical transmission of the rubella in the first trimester seems to vary among different populations, as well as the presence of the associated defects in the new-born. Invasive diagnosis and ultrasonographic follow-up presented good sensitivity and specificity. We could establish the pattern of fetal grown associated to the infection. The isolated presence of a positive rubella IgM in pregnancy did not correlated with congenital rubella, but it can be related to other congenital infections.
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Books on the topic "Rubeole congenitale"

1

Lebo, Emmaculate, and Susan Reef. Rubella Virus. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190604813.003.0013.

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Rubella infection in pregnant women, especially during the first trimester, can result in miscarriages, fetal deaths, stillbirths, or a constellation of congenital anomalies known as congenital rubella syndrome (CRS). Infants born with CRS often present with a myriad of classical symptoms, including hearing impairment, congenital heart defects, cataracts, and mental impairment. The risk of developing a congenital defect is highest when the rubella infection occurs during the first 12 weeks of gestation. The risks associated with fetal infection are primarily in pregnant women who are not immune to the rubella virus; immunity is acquired through vaccination with a rubella-containing vaccine or develops naturally following infection with rubella virus. In 2010, approximately 105,000 children with CRS were born globally, with an estimated 49,229 and 38,712 CRS cases born in the Southeast Asia and African WHO regions, respectively. Significant progress has been made toward reducing the burden of rubella and CRS cases globally through the introduction of rubella-containing vaccines in many countries.
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WHO Regional Office for the Eastern Mediterranean. Field Guidelines for Surveillance of Measles, Rubella and Congenital Rubella Syndrome. World Health Organization, 2011.

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Bale, James F. Congenital and Perinatal Viral Infections. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0160.

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Despite remarkable advancements in the treatment and prevention of infectious diseases, congenital (also known as intrauterine) and perinatal (also known as neonatal) infections remain major causes of permanent neurodevelopmental disabilities worldwide. Fortunately, relatively few viral pathogens can infect the developing fetus or the newborn postnatally and induce neurological disease. These pathogens include cytomegalovirus, rubella virus, herpes simplex virus types 1 and 2, varicella zoster virus, lymphocytic choriomeningitis virus, the nonpolio enteroviruses, parechovirus, and human immunodeficiency virus. This chapter describes the clinical manifestations, diagnosis, treatment, and outcome of these congenital and perinatal viral infections.
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PAHO. Elimination of Rubella and Congenital Rubella Syndrome: Field Guide (PAHO Scientific Publications). Pan American Health Organization, 2006.

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E, Banatvala J., and Peckham C. A, eds. Rubella viruses. Amsterdam: Elsevier, 2007.

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(Editor), Jangu Banatvala, and Catherine Peckham (Editor), eds. Rubella Viruses, Volume 15 (Perspectives in Medical Virology) (Perspectives in Medical Virology). Elsevier Science, 2007.

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Fox, Grenville, Nicholas Hoque, and Timothy Watts. Infection. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198703952.003.0012.

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This chapter provides a problem-oriented approach to investigation and treatment of early and late onset neonatal bacterial infection, including group B streptococcus, meningitis, urine infection, conjunctivitis, umbilical sepsis, osteomyelitis, and septic arthritis. In addition, the prevention and management of congenital infection is covered, including hepatitis B and C, HIV, syphilis, CMV, toxoplasma, rubella, herpes simplex, and chickenpox. Other topics covered are infection control (including MRSA), fungal sepsis, TB, and an overview of immunizations in the first year of life.
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Murray, Virginia, Amina Aitsi-Selmi, and Alex G. Stewart. Global disasters and risk reduction strategies. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198745471.003.0028.

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As the global population increase, the effects of disasters also increase. However, through improved building codes and other disaster risk reduction interventions, the number of deaths appears to be reducing. International frameworks for reduction and response are being built and an audit of the NHS demonstrated the advantages of an integrated health service. Fact sheets, produced internationally with UK involvement, on several aspects of disaster risk reduction have started to increase awareness of the wide variety of needs, although mental health issues need further research. Not all global disasters with far-reaching consequences are catastrophic in nature. The circumstances of congenital rubella and iodine deficiency show the strengths of international collaboration and the need for high-quality science. This chapter explains disaster risk reduction and sets it in its international perspective, with examples of wide-ranging agreements and frameworks, and their application to the wider UK health service.
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Book chapters on the topic "Rubeole congenitale"

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Miller, C. L., and H. Bradley. "Congenital rubella." In Profound Retardation and Multiple Impairment, 93–113. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4899-7146-3_7.

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Hutto, Cecelia. "Rubella." In Congenital and Perinatal Infections, 123–29. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1385/1-59259-965-6:123.

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Bien, Christian G., Christian E. Elger, Ali R. Afzal, Sirajedin Natah, Ritva Häyrinen-Immonen, Yrjö Konttinen, George S. Zubenko, et al. "Rubella Syndrome, Congenital." In Encyclopedia of Molecular Mechanisms of Disease, 1874–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_3281.

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Peters, Nils, Martin Dichgans, Sankar Surendran, Josep M. Argilés, Francisco J. López-Soriano, Sílvia Busquets, Klaus Dittmann, et al. "Congenital Rubella Syndrome." In Encyclopedia of Molecular Mechanisms of Disease, 403–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_9115.

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Orellana, Juan, and Alan H. Friedman. "Rubella Retinopathy." In Clinico-Pathological Atlas of Congenital Fundus Disorders, 57–58. New York, NY: Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-9320-7_9.

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Anderson, Roy M. "Congenital Rubella Syndrome (C.R.S.): Models of Disease Control by Vaccination." In Lecture Notes in Biomathematics, 106–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-93287-8_16.

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Katow, Shigetaka, and Satoko Arai. "Quantitation of Rubella Virus Genome by QPCR and Its Application to Resolution for Mechanism of Congenital Rubella Syndrome." In Modern Applications of DNA Amplification Techniques, 93–100. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5379-3_10.

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Kudo, Fumiyo. "Congenital Hearing Loss in Virus Infection: Rubella and CMV Infection in Children." In Hearing Impairment, 170–77. Tokyo: Springer Japan, 2004. http://dx.doi.org/10.1007/978-4-431-68397-1_33.

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McEvoy, Robert C., Barbara Fedun, Louis Z. Cooper, Nancy M. Thomas, Santiago Rodriguez De Cordoba, Pablo Rubinstein, and Fredda Ginsberg-Fellner. "Children at High Risk of Diabetes Mellitus: New York Studies of Families with Diabetes and of Children with Congenital Rubella Syndrome." In Prediabetes, 221–27. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-5616-5_27.

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Arvind, R. "Congenital Rubella." In 100+ Clinical Cases in Pediatrics, 329. Jaypee Brothers Medical Publishers (P) Ltd., 2016. http://dx.doi.org/10.5005/jp/books/12794_58.

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Conference papers on the topic "Rubeole congenitale"

1

Pasaribu, Ayodhia Pitaloka, Munira Ulfa, Syahril Pasaribu, and Irma Sari Nasution. "Congenital Rubella Syndrome: A Case Report." In The 2nd International Conference on Tropical Medicine and Infectious Disease. SCITEPRESS - Science and Technology Publications, 2019. http://dx.doi.org/10.5220/0009861501110114.

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Rosyada, Amrina, Dini Arista Putri, and Rini Mutahar. "Family Awareness of Congenital Rubella Syndrome in Palembang, Indonesia." In 2nd Sriwijaya International Conference of Public Health (SICPH 2019). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.200612.003.

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