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1

Hagmaier, K., N. Stock, B. Precious, et al. "Mapuera virus, a rubulavirus that inhibits interferon signalling in a wide variety of mammalian cells without degrading STATs." Journal of General Virology 88, no. 3 (2007): 956–66. http://dx.doi.org/10.1099/vir.0.82579-0.

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Mapuera virus (MPRV) is a paramyxovirus that was originally isolated from bats, but its host range remains unknown. It was classified as a member of the genus Rubulavirus on the basis of structural and genetic features. Like other rubulaviruses it encodes a V protein (MPRV/V) that functions as an interferon (IFN) antagonist. Here we show that MPRV/V differs from the IFN antagonists of other rubulaviruses in that it does not induce the proteasomal degradation of STAT proteins, key factors in the IFN signalling cascade. Rather, MPRV/V prevents the nuclear translocation of STATs in response to IF
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2

Mortlock, Marinda, Muriel Dietrich, Jacqueline Weyer, Janusz T. Paweska, and Wanda Markotter. "Co-Circulation and Excretion Dynamics of Diverse Rubula- and Related Viruses in Egyptian Rousette Bats from South Africa." Viruses 11, no. 1 (2019): 37. http://dx.doi.org/10.3390/v11010037.

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The Egyptian rousette bat (Rousettus aegyptiacus) has previously been implicated as the natural host of a zoonotic rubulavirus; however, its association with rubulaviruses has been studied to a limited extent. Urine, spleen, and other organs collected from the R. aegyptiacus population within South Africa were tested with a hemi-nested RT-PCR assay targeting a partial polymerase gene region of viruses from the Avula- and Rubulavirus genera. Urine was collected over a 14-month period to study the temporal dynamics of viral excretion. Diverse rubulaviruses, including viruses related to human mum
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3

Wilson, Rebecca L., Sandra M. Fuentes, Ping Wang, et al. "Function of Small Hydrophobic Proteins of Paramyxovirus." Journal of Virology 80, no. 4 (2006): 1700–1709. http://dx.doi.org/10.1128/jvi.80.4.1700-1709.2006.

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ABSTRACT Mumps virus (MuV), a rubulavirus of the paramyxovirus family, causes acute infections in humans. MuV has seven genes including a small hydrophobic (SH) gene, which encodes a type I membrane protein of 57 amino acid residues. The function of the SH protein is not clear, although its expression is not necessary for growth of MuV in tissue culture cells. It is speculated that MuV SH plays a role in viral pathogenesis. Simian virus 5 (SV5), a closely related rubulavirus, encodes a 44-amino-acid-residue SH protein. Recombinant SV5 lacking the SH gene (rSV5ΔSH) is viable and has no growth d
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4

Yuan, Lihong, Min Li, Linmiao Li, et al. "Evidence for retrovirus and paramyxovirus infection of multiple bat species in china." Viruses 6, no. 5 (2014): 2138–54. https://doi.org/10.5281/zenodo.14822584.

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(Uploaded by Plazi for the Bat Literature Project) Bats are recognized reservoirs for many emerging zoonotic viruses of public health importance. Identifying and cataloguing the viruses of bats is a logical approach to evaluate the range of potential zoonoses of bat origin. We characterized the fecal pathogen microbiome of both insectivorous and frugivorous bats, incorporating 281 individual bats comprising 20 common species, which were sampled in three locations of Yunnan province, by combining reverse transcription polymerase chain reaction (RT-PCR) assays and next-generation sequencing. Sev
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5

Brown, Brent, Tanya Gravier, Ingo Fricke, et al. "Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses." Immuno 3, no. 2 (2023): 160–81. http://dx.doi.org/10.3390/immuno3020011.

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Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009). The latter is considered to have initiated two prior pandemics in 1918 and 1977, known as the “Spanish Flu” and “Russian Flu”, respectively. Here, we discuss other emerging infections that could be potential public health threats. These include Henipaviruses, which are members of the family Paramyxoviridae that infect bats and other mammals. Paramyxoviridae also include Parainfluenza and Mumps viruses (Rubulavirus) but
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6

Baker, K. S., S. Todd, G. A. Marsh, et al. "Novel, potentially zoonotic paramyxoviruses from the African straw-colored fruit bat Eidolon helvum." J Virol 87, no. 3 (2013): 1348–58. https://doi.org/10.5281/zenodo.13526574.

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(Uploaded by Plazi for the Bat Literature Project) Bats carry a variety of paramyxoviruses that impact human and domestic animal health when spillover occurs. Recent studies have shown a great diversity of paramyxoviruses in an urban-roosting population of straw-colored fruit bats in Ghana. Here, we investigate this further through virus isolation and describe two novel rubulaviruses: Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2). The viruses form a phylogenetic cluster with each other and other bat-derived rubulaviruses, such as Tuhoko viruses, Menangle virus, and Tioman virus. We d
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7

Baker, K. S., S. Todd, G. A. Marsh, et al. "Novel, potentially zoonotic paramyxoviruses from the African straw-colored fruit bat Eidolon helvum." J Virol 87, no. 3 (2013): 1348–58. https://doi.org/10.5281/zenodo.13526574.

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(Uploaded by Plazi for the Bat Literature Project) Bats carry a variety of paramyxoviruses that impact human and domestic animal health when spillover occurs. Recent studies have shown a great diversity of paramyxoviruses in an urban-roosting population of straw-colored fruit bats in Ghana. Here, we investigate this further through virus isolation and describe two novel rubulaviruses: Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2). The viruses form a phylogenetic cluster with each other and other bat-derived rubulaviruses, such as Tuhoko viruses, Menangle virus, and Tioman virus. We d
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8

Baker, K. S., S. Todd, G. A. Marsh, et al. "Novel, potentially zoonotic paramyxoviruses from the African straw-colored fruit bat Eidolon helvum." J Virol 87, no. 3 (2013): 1348–58. https://doi.org/10.5281/zenodo.13526574.

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(Uploaded by Plazi for the Bat Literature Project) Bats carry a variety of paramyxoviruses that impact human and domestic animal health when spillover occurs. Recent studies have shown a great diversity of paramyxoviruses in an urban-roosting population of straw-colored fruit bats in Ghana. Here, we investigate this further through virus isolation and describe two novel rubulaviruses: Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2). The viruses form a phylogenetic cluster with each other and other bat-derived rubulaviruses, such as Tuhoko viruses, Menangle virus, and Tioman virus. We d
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9

Baker, K. S., S. Todd, G. A. Marsh, et al. "Novel, potentially zoonotic paramyxoviruses from the African straw-colored fruit bat Eidolon helvum." J Virol 87, no. 3 (2013): 1348–58. https://doi.org/10.5281/zenodo.13526574.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Bats carry a variety of paramyxoviruses that impact human and domestic animal health when spillover occurs. Recent studies have shown a great diversity of paramyxoviruses in an urban-roosting population of straw-colored fruit bats in Ghana. Here, we investigate this further through virus isolation and describe two novel rubulaviruses: Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2). The viruses form a phylogenetic cluster with each other and other bat-derived rubulaviruses, such as Tuhoko viruses, Menangle virus, and Tioman virus. We d
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10

Hernández, Jesús, Julio Reyes-Leyva, Roberto Zenteno, Humberto Ramı́rez, Pablo Hernández-Jauregui, and Edgar Zenteno. "Immunity to porcine rubulavirus infection in adult swine." Veterinary Immunology and Immunopathology 64, no. 4 (1998): 367–81. http://dx.doi.org/10.1016/s0165-2427(98)00169-x.

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11

Rivera-Benitez, José Francisco, Sandra Cuevas-Romero, Armando Pérez-Torres, Julio Reyes-Leyva, Jesús Hernández, and Humberto Ramírez-Mendoza. "Respiratory disease in growing pigs after Porcine rubulavirus experimental infection." Virus Research 176, no. 1-2 (2013): 137–43. http://dx.doi.org/10.1016/j.virusres.2013.05.017.

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12

Hernández-Jáuregui, P., H. Ramı́rez Mendoza, C. Mercado Garcı́a, J. Moreno-López, and S. Kennedy. "Experimental Porcine Rubulavirus (La Piedad-Michoacan virus) Infection in Pregnant Gilts." Journal of Comparative Pathology 130, no. 1 (2004): 1–6. http://dx.doi.org/10.1016/s0021-9975(03)00058-6.

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13

Herrera, Jenifer, Luis Gómez-Núñez, Rocío Lara-Romero, et al. "Acute neurologic disease in Porcine rubulavirus experimentally infected piglets." Virus Research 230 (February 2017): 50–58. http://dx.doi.org/10.1016/j.virusres.2017.01.010.

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14

Flores-Ocelotl, María del Rosario, Nora Hilda Rosas-Murrieta, Verónica Vallejo-Ruiz, Julio Reyes-Leyva, Irma Herrera-Camacho, and Gerardo Santos-López. "Transcription of interferon stimulated genes in response to porcine rubulavirus infection in vitro." Brazilian Journal of Microbiology 42, no. 3 (2011): 1167–75. http://dx.doi.org/10.1590/s1517-83822011000300041.

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15

Baker, Kate S., Shawn Todd, Glenn A. Marsh, et al. "Novel, Potentially Zoonotic Paramyxoviruses from the African Straw-Colored Fruit Bat Eidolon helvum." Journal of Virology 87, no. 3 (2012): 1348–58. http://dx.doi.org/10.1128/jvi.01202-12.

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ABSTRACTBats carry a variety of paramyxoviruses that impact human and domestic animal health when spillover occurs. Recent studies have shown a great diversity of paramyxoviruses in an urban-roosting population of straw-colored fruit bats in Ghana. Here, we investigate this further through virus isolation and describe two novel rubulaviruses: Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2). The viruses form a phylogenetic cluster with each other and other bat-derived rubulaviruses, such as Tuhoko viruses, Menangle virus, and Tioman virus. We developed AchPV1- and AchPV2-specific serolo
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16

Mortlock, Marinda, Muriel Dietrich, Jacqueline Weyer, Janusz T. Paweska, and Wanda Markotter. "Co-circulation and excretion dynamics of diverse rubula-and related viruses in Egyptian rousette bats from South Africa." Viruses 11, no. 1 (2019): 37. https://doi.org/10.5281/zenodo.13524388.

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17

Mortlock, Marinda, Muriel Dietrich, Jacqueline Weyer, Janusz T. Paweska, and Wanda Markotter. "Co-circulation and excretion dynamics of diverse rubula-and related viruses in Egyptian rousette bats from South Africa." Viruses 11, no. 1 (2019): 37. https://doi.org/10.5281/zenodo.13524388.

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18

Mortlock, Marinda, Muriel Dietrich, Jacqueline Weyer, Janusz T. Paweska, and Wanda Markotter. "Co-circulation and excretion dynamics of diverse rubula-and related viruses in Egyptian rousette bats from South Africa." Viruses 11, no. 1 (2019): 37. https://doi.org/10.5281/zenodo.13524388.

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19

Mortlock, Marinda, Muriel Dietrich, Jacqueline Weyer, Janusz T. Paweska, and Wanda Markotter. "Co-circulation and excretion dynamics of diverse rubula-and related viruses in Egyptian rousette bats from South Africa." Viruses 11, no. 1 (2019): 37. https://doi.org/10.5281/zenodo.13524388.

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20

Barr, Jennifer, Shawn Todd, Gary Crameri, et al. "Animal infection studies of two recently discovered African bat paramyxoviruses, Achimota 1 and Achimota 2." Scientific Reports 8, no. 1 (2018): 12744. https://doi.org/10.5281/zenodo.13487919.

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(Uploaded by Plazi for the Bat Literature Project) Abstract Bats are implicated as the natural reservoirs for several highly pathogenic viruses that can infect other animal species, including man. Here, we investigate the potential for two recently discovered bat rubulaviruses, Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2), isolated from urine collected under urban bat ( Eidolon helvum ) roosts in Ghana, West Africa, to infect small laboratory animals. AchPV1 and AchPV2 are classified in the family Paramyxoviridae and cluster with other bat derived zoonotic rubulaviruses (i.e. Sosuga
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21

Barr, Jennifer, Shawn Todd, Gary Crameri, et al. "Animal infection studies of two recently discovered African bat paramyxoviruses, Achimota 1 and Achimota 2." Scientific Reports 8, no. 1 (2018): 12744. https://doi.org/10.5281/zenodo.13529850.

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(Uploaded by Plazi for the Bat Literature Project) Bats are implicated as the natural reservoirs for several highly pathogenic viruses that can infect other animal species, including man. Here, we investigate the potential for two recently discovered bat rubulaviruses, Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2), isolated from urine collected under urban bat (Eidolon helvum) roosts in Ghana, West Africa, to infect small laboratory animals. AchPV1 and AchPV2 are classified in the family Paramyxoviridae and cluster with other bat derived zoonotic rubulaviruses (i.e. Sosuga, Menangle
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22

Barr, Jennifer, Shawn Todd, Gary Crameri, et al. "Animal infection studies of two recently discovered African bat paramyxoviruses, Achimota 1 and Achimota 2." Scientific Reports 8, no. 1 (2018): 12744. https://doi.org/10.5281/zenodo.13487919.

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(Uploaded by Plazi for the Bat Literature Project) Abstract Bats are implicated as the natural reservoirs for several highly pathogenic viruses that can infect other animal species, including man. Here, we investigate the potential for two recently discovered bat rubulaviruses, Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2), isolated from urine collected under urban bat ( Eidolon helvum ) roosts in Ghana, West Africa, to infect small laboratory animals. AchPV1 and AchPV2 are classified in the family Paramyxoviridae and cluster with other bat derived zoonotic rubulaviruses (i.e. Sosuga
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23

Barr, Jennifer, Shawn Todd, Gary Crameri, et al. "Animal infection studies of two recently discovered African bat paramyxoviruses, Achimota 1 and Achimota 2." Scientific Reports 8, no. 1 (2018): 12744. https://doi.org/10.5281/zenodo.13529850.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Bats are implicated as the natural reservoirs for several highly pathogenic viruses that can infect other animal species, including man. Here, we investigate the potential for two recently discovered bat rubulaviruses, Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2), isolated from urine collected under urban bat (Eidolon helvum) roosts in Ghana, West Africa, to infect small laboratory animals. AchPV1 and AchPV2 are classified in the family Paramyxoviridae and cluster with other bat derived zoonotic rubulaviruses (i.e. Sosuga, Menangle
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24

Barr, Jennifer, Shawn Todd, Gary Crameri, et al. "Animal infection studies of two recently discovered African bat paramyxoviruses, Achimota 1 and Achimota 2." Scientific Reports 8, no. 1 (2018): 12744. https://doi.org/10.5281/zenodo.13487919.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Abstract Bats are implicated as the natural reservoirs for several highly pathogenic viruses that can infect other animal species, including man. Here, we investigate the potential for two recently discovered bat rubulaviruses, Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2), isolated from urine collected under urban bat ( Eidolon helvum ) roosts in Ghana, West Africa, to infect small laboratory animals. AchPV1 and AchPV2 are classified in the family Paramyxoviridae and cluster with other bat derived zoonotic rubulaviruses (i.e. Sosuga
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25

Barr, Jennifer, Shawn Todd, Gary Crameri, et al. "Animal infection studies of two recently discovered African bat paramyxoviruses, Achimota 1 and Achimota 2." Scientific Reports 8, no. 1 (2018): 12744. https://doi.org/10.5281/zenodo.13487919.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Abstract Bats are implicated as the natural reservoirs for several highly pathogenic viruses that can infect other animal species, including man. Here, we investigate the potential for two recently discovered bat rubulaviruses, Achimota virus 1 (AchPV1) and Achimota virus 2 (AchPV2), isolated from urine collected under urban bat ( Eidolon helvum ) roosts in Ghana, West Africa, to infect small laboratory animals. AchPV1 and AchPV2 are classified in the family Paramyxoviridae and cluster with other bat derived zoonotic rubulaviruses (i.e. Sosuga
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26

Hjertner, B., T. Linné, and J. Moreno-Lόpez. "Establishment and Characterisation of a Porcine Rubulavirus (LPMV) Persistent Infection in Porcine Kidney Cells." Acta Veterinaria Scandinavica 38, no. 3 (1997): 213–24. http://dx.doi.org/10.1186/bf03548484.

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27

Annand, E., J. Barr, N. Singanallur Balasubramanian, et al. "Spillover of bat borne Rubulavirus in Australian horses – Horses as sentinels for emerging infectious diseases." International Journal of Infectious Diseases 101 (December 2020): 401–2. http://dx.doi.org/10.1016/j.ijid.2020.09.1051.

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28

Annand, E., J. Barr, N. Singanallur Balasubramanian, et al. "Spillover of bat borne rubulavirus in Australian horses – Horses as sentinels for emerging infectious diseases." International Journal of Infectious Diseases 101 (December 2020): 406. http://dx.doi.org/10.1016/j.ijid.2020.09.1066.

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29

Kurth, Andreas, Claudia Kohl, Annika Brinkmann, et al. "Novel Paramyxoviruses in Free-Ranging European Bats." PLOS ONE 7, no. 6 (2012): e38688. https://doi.org/10.5281/zenodo.13530068.

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(Uploaded by Plazi for the Bat Literature Project) The zoonotic potential of paramyxoviruses is particularly demonstrated by their broad host range like the highly pathogenic Hendra and Nipah viruses originating from bats. But while so far all bat-borne paramyxoviruses have been identified in fruit bats across Africa, Australia, South America, and Asia, we describe the detection and characterization of the first paramyxoviruses in free-ranging European bats. Moreover, we examined the possible impact of paramyxovirus infection on individual animals by comparing histo-pathological findings and v
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30

Kurth, Andreas, Claudia Kohl, Annika Brinkmann, et al. "Novel Paramyxoviruses in Free-Ranging European Bats." PLOS ONE 7, no. 6 (2012): e38688. https://doi.org/10.5281/zenodo.13530068.

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(Uploaded by Plazi for the Bat Literature Project) The zoonotic potential of paramyxoviruses is particularly demonstrated by their broad host range like the highly pathogenic Hendra and Nipah viruses originating from bats. But while so far all bat-borne paramyxoviruses have been identified in fruit bats across Africa, Australia, South America, and Asia, we describe the detection and characterization of the first paramyxoviruses in free-ranging European bats. Moreover, we examined the possible impact of paramyxovirus infection on individual animals by comparing histo-pathological findings and v
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31

Rivera-Benitez, José Francisco, Jazmín De la Luz-Armendáriz, Manuel Saavedra-Montañez, et al. "Co-infection of classic swine H1N1 influenza virus in pigs persistently infected with porcine rubulavirus." Veterinary Microbiology 184 (February 2016): 31–39. http://dx.doi.org/10.1016/j.vetmic.2016.01.005.

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32

Nishio, Machiko, Masato Tsurudome, Morihiro Ito, Dominique Garcin, Daniel Kolakofsky, and Yasuhiko Ito. "Identification of Paramyxovirus V Protein Residues Essential for STAT Protein Degradation and Promotion of Virus Replication." Journal of Virology 79, no. 13 (2005): 8591–601. http://dx.doi.org/10.1128/jvi.79.13.8591-8601.2005.

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ABSTRACT Some paramyxovirus V proteins induce STAT protein degradation, and the amino acids essential for this process in the human parainfluenza virus type 2 (hPIV2) V protein have been studied. Various recombinant hPIV2s and cell lines constitutively expressing various mutant V proteins were generated. We found that V proteins with replacement of Cys residues of the Cys cluster were still able to bind STATs but were unable to induce their degradation. The hPIV2 V protein binds STATs via a W-(X)3-W-(X)9-W Trp motif located just upstream of the Cys cluster. Replacements of two or more Trp resi
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33

Wiman, Ann-Christin, Bernt Hjertner, Tommy Linné, et al. "Porcine Rubulavirus Lpmv Rna Persists in the Central Nervous System of Pigs After Recovery from Acute Infection." Journal of Neurovirology 4, no. 5 (1998): 545–52. http://dx.doi.org/10.3109/13550289809113499.

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34

Johnson, Rebecca, Mary Tachedjian, Brenton Rowe, et al. "Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets." Viruses 10, no. 12 (2018): 675. http://dx.doi.org/10.3390/v10120675.

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Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in Alstonville, New South Wales. Characterization of AlsPV by whole-genome sequencing and analyzing antigenic relatedness revealed it is a rubulavirus that is closely related to parainfluenza virus 5 (PIV5). Intranasal exposure of mice to AlsPV resulted in no clinical signs of disease, although viral RNA was detected in the olfactory bulbs of two mi
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35

Johnson, Rebecca, Mary Tachedjian, Brenton Rowe, et al. "Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets." Viruses 10, no. 12 (2018): 675. https://doi.org/10.5281/zenodo.13445961.

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(Uploaded by Plazi for the Bat Literature Project) Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in Alstonville, New South Wales. Characterization of AlsPV by whole-genome sequencing and analyzing antigenic relatedness revealed it is a rubulavirus that is closely related to parainfluenza virus 5 (PIV5). Intranasal exposure of mice to AlsPV resulted in no clinical signs of disease, although vira
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36

Johnson, Rebecca, Mary Tachedjian, Brenton Rowe, et al. "Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets." Viruses 10, no. 12 (2018): 675. https://doi.org/10.5281/zenodo.13445961.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in Alstonville, New South Wales. Characterization of AlsPV by whole-genome sequencing and analyzing antigenic relatedness revealed it is a rubulavirus that is closely related to parainfluenza virus 5 (PIV5). Intranasal exposure of mice to AlsPV resulted in no clinical signs of disease, although vira
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37

Johnson, Rebecca, Mary Tachedjian, Brenton Rowe, et al. "Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets." Viruses 10, no. 12 (2018): 675. https://doi.org/10.5281/zenodo.13445961.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in Alstonville, New South Wales. Characterization of AlsPV by whole-genome sequencing and analyzing antigenic relatedness revealed it is a rubulavirus that is closely related to parainfluenza virus 5 (PIV5). Intranasal exposure of mice to AlsPV resulted in no clinical signs of disease, although vira
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38

Johnson, Rebecca, Mary Tachedjian, Brenton Rowe, et al. "Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets." Viruses 10, no. 12 (2018): 675. https://doi.org/10.5281/zenodo.13445961.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in Alstonville, New South Wales. Characterization of AlsPV by whole-genome sequencing and analyzing antigenic relatedness revealed it is a rubulavirus that is closely related to parainfluenza virus 5 (PIV5). Intranasal exposure of mice to AlsPV resulted in no clinical signs of disease, although vira
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39

Johnson, Rebecca, Mary Tachedjian, Brenton Rowe, et al. "Alston Virus, a Novel Paramyxovirus Isolated from Bats Causes Upper Respiratory Tract Infection in Experimentally Challenged Ferrets." Viruses 10, no. 12 (2018): 675. https://doi.org/10.5281/zenodo.13445961.

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Abstract:
(Uploaded by Plazi for the Bat Literature Project) Multiple viruses with zoonotic potential have been isolated from bats globally. Here we describe the isolation and characterization of a novel paramyxovirus, Alston virus (AlsPV), isolated from urine collected from an Australian pteropid bat colony in Alstonville, New South Wales. Characterization of AlsPV by whole-genome sequencing and analyzing antigenic relatedness revealed it is a rubulavirus that is closely related to parainfluenza virus 5 (PIV5). Intranasal exposure of mice to AlsPV resulted in no clinical signs of disease, although vira
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40

Ulane, Christina M., Jason J. Rodriguez, Jean-Patrick Parisien, and Curt M. Horvath. "STAT3 Ubiquitylation and Degradation by Mumps Virus Suppress Cytokine and Oncogene Signaling." Journal of Virology 77, no. 11 (2003): 6385–93. http://dx.doi.org/10.1128/jvi.77.11.6385-6393.2003.

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ABSTRACT Mumps virus is a common infectious agent of humans, causing parotitis, meningitis, encephalitis, and orchitis. Like other paramyxoviruses in the genus Rubulavirus, mumps virus catalyzes the proteasomal degradation of cellular STAT1 protein, a means for escaping antiviral responses initiated by alpha/beta and gamma interferons. We demonstrate that mumps virus also eliminates cellular STAT3, a protein that mediates transcriptional responses to cytokines, growth factors, nonreceptor tyrosine kinases, and a variety of oncogenic stimuli. STAT1 and STAT3 are independently targeted by a sing
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Svenda, M., M. Berg, J. Moreno-López, and T. Linné. "Analysis of the large (L) protein gene of the procine rubulavirus LPMV: identification of possible functional domains." Virus Research 48, no. 1 (1997): 57–70. http://dx.doi.org/10.1016/s0168-1702(96)01426-8.

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Puri, Mamta, Ken Lemon, W. Paul Duprex, Bertus K. Rima, and Curt M. Horvath. "A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting." Journal of Virology 83, no. 13 (2009): 6347–56. http://dx.doi.org/10.1128/jvi.00596-09.

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ABSTRACT Mumps virus, like other paramyxoviruses in the Rubulavirus genus, encodes a V protein that can assemble a ubiquitin ligase complex from cellular components, leading to the destruction of cellular signal transducer and activator of transcription (STAT) proteins. While many V proteins target the interferon-activated STAT1 or STAT2 protein, mumps virus V protein is unique in its ability to also target STAT3 for ubiquitin modification and proteasome-mediated degradation. Here we report that a single amino acid substitution in the mumps virus V protein, E95D, results in defective STAT3 tar
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43

Alpízar, Aide, Joaquim Segalés, Simón Martínez, et al. "Histopathological and virological findings in emaciated pigs from Mexico: an exploratory study." Acta Veterinaria Brno 87, no. 3 (2018): 213–17. http://dx.doi.org/10.2754/avb201887030213.

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The objective of this work was to detect the presence of three main pig respiratory viral agents (porcine rubulavirus [PorPV], porcine circovirus type 2 [PCV-2], and porcine reproductive and respiratory syndrome virus [PRRSV]) in tissues of emaciated piglets from the Baj'o Region (Mexico). Necropsies and histopathological studies of 37 pigs with poor body condition were performed; viruses were detected by molecular biology methods and PCV-2 was further assessed by immunohistochemistry (IHC). Histopathologically, interstitial pneumonia was observed in 25/37 (68%) of the piglets. Also, a varying
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Hjertner, B., A. C. Wiman, M. Svenda, M. Berg, J. Moreno-López, and T. Linné. "Multiple factors including subgenomic RNAs and reduced viral protein expression are associated with a persistent infection by porcine rubulavirus (LPMV)." Archives of Virology 143, no. 3 (1998): 425–39. http://dx.doi.org/10.1007/s007050050300.

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Garcin, Dominique, Jean-Baptiste Marq, Stephen Goodbourn, and Daniel Kolakofsky. "The Amino-Terminal Extensions of the Longer Sendai Virus C Proteins Modulate pY701-Stat1 and Bulk Stat1 Levels Independently of Interferon Signaling." Journal of Virology 77, no. 4 (2003): 2321–29. http://dx.doi.org/10.1128/jvi.77.4.2321-2329.2003.

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ABSTRACT The Sendai virus (SeV) C proteins are known to interact with Stat1 to prevent interferon (IFN)-induced pY701-Stat1 formation and IFN signaling. Nevertheless, pY701-Stat1 levels paradoxically increase during SeV infection. The C proteins also induce bulk Stat1 instability in some cells, similar to rubulavirus V proteins. We have found that SeV infection increases pY701-Stat1 levels even in cells in which bulk Stat1 levels strongly decrease. Remarkably, both the decrease in bulk Stat1 levels and the increase in pY701-Stat1 levels were found to be independent of the IFN signaling system,
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Svenda, Martin, Bernt Hjertner, Tommy Linné, and Mikael Berg. "Both the P and V proteins of the porcine rubulavirus LPMV interact with the NP protein via their respective C-terminal unique parts." Virus Research 83, no. 1-2 (2002): 31–41. http://dx.doi.org/10.1016/s0168-1702(01)00406-3.

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47

Young, Virginia A., and Griffith D. Parks. "Simian Virus 5 Is a Poor Inducer of Chemokine Secretion from Human Lung Epithelial Cells: Identification of Viral Mutants That Activate Interleukin-8 Secretion by Distinct Mechanisms." Journal of Virology 77, no. 12 (2003): 7124–30. http://dx.doi.org/10.1128/jvi.77.12.7124-7130.2003.

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ABSTRACT We have compared chemokine secretion from human lung A549 cells infected with simian virus 5 (SV5) with other members of the Rubulavirus genus of paramyxoviruses. High levels of the chemokines interleukin-8 (IL-8) and macrophage chemoattractant protein-1 (MCP-1) were secreted from A549 cells infected with Human parainfluenza virus type 2 (HPIV-2) but not from cells infected with wild-type (WT) SV5. The lack of IL-8 secretion from SV5-infected cells was not due to a global block in all signal transduction pathways leading to IL-8 secretion, since SV5-infected A549 cells secreted IL-8 a
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Cuevas-Romero, S., E. Hernández-Baumgarten, S. Kennedy, P. Hernández-Jáuregui, M. Berg, and J. Moreno-López. "Long-term RNA persistence of Porcine rubulavirus (PorPV-LPMV) after an outbreak of a natural infection: The detection of viral mRNA in sentinel pigs suggests viral transmission." Virus Research 188 (August 2014): 155–61. http://dx.doi.org/10.1016/j.virusres.2014.04.012.

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Sasaki, Michihito, Agus Setiyono, Ekowati Handharyani, et al. "Molecular detection of a novel paramyxovirus in fruit bats from Indonesia." Virology Journal 9, no. 1 (2012): 240. https://doi.org/10.5281/zenodo.13431216.

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(Uploaded by Plazi for the Bat Literature Project) Background: Fruit bats are known to harbor zoonotic paramyxoviruses including Nipah, Hendra, and Menangle viruses. The aim of this study was to detect the presence of paramyxovirus RNA in fruit bats from Indonesia. Methods: RNA samples were obtained from the spleens of 110 fruit bats collected from four locations in Indonesia. All samples were screened by semi-nested broad spectrum reverse transcription PCR targeting the paramyxovirus polymerase (L) genes. Results: Semi-nested reverse transcription PCR detected five previously unidentified par
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Sasaki, Michihito, Agus Setiyono, Ekowati Handharyani, et al. "Molecular detection of a novel paramyxovirus in fruit bats from Indonesia." Virology Journal 9, no. 1 (2012): 240. https://doi.org/10.5281/zenodo.13431216.

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(Uploaded by Plazi for the Bat Literature Project) Background: Fruit bats are known to harbor zoonotic paramyxoviruses including Nipah, Hendra, and Menangle viruses. The aim of this study was to detect the presence of paramyxovirus RNA in fruit bats from Indonesia. Methods: RNA samples were obtained from the spleens of 110 fruit bats collected from four locations in Indonesia. All samples were screened by semi-nested broad spectrum reverse transcription PCR targeting the paramyxovirus polymerase (L) genes. Results: Semi-nested reverse transcription PCR detected five previously unidentified par
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