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1

Sevostyanova, N., and S. Batashev. "Cyclohexene hydrocarbomethoxylation catalysed by ruthenium compounds." Bulletin of Science and Practice 456, no. 11 (12) (2016): 99–105. https://doi.org/10.5281/zenodo.166790.

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This paper presents a catalytic activity of ruthenium (III) compounds in the model reaction of cyclohexene hydrocarbomethoxylation. The objective of the work was contained in the determination of the most active ruthenium catalyst of this reaction. The kinetic method was used as the main method of investigation. The gas–liquid chromatography method was used to analyze the reaction mass. Accordingly to approbation of ruthenium (III) acetylacetonate and chloride as catalysts of cyclohexene hydrocarbomethoxylation the higher catalytic activity of ruthenium chloride was determined. With using of r
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2

Kanaoujiya, Rahul, and Shekhar Srivastava. "Ruthenium based antifungal compounds and their activity." Research Journal of Chemistry and Environment 25, no. 7 (2021): 177–82. http://dx.doi.org/10.25303/257rjce17721.

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Ruthenium is recognized as a highly attractive alternative to platinum since the toxicity of many ruthenium compounds is lower and some complexes are quite selective for antifungal drugs. Ruthenium has various chemical properties these chemical properties are very useful for antifungal drug design. Ruthenium compounds have several types of advantages as antifungal drugs because of lower toxicity. . Ruthenium has unique properties making it of particularly use as fungal in drug design specially in antifungal drugs. Several types of ruthenium complexes and their antifungal activity standards are
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3

Motswainyana, William M., and Peter A. Ajibade. "Anticancer Activities of Mononuclear Ruthenium(II) Coordination Complexes." Advances in Chemistry 2015 (February 19, 2015): 1–21. http://dx.doi.org/10.1155/2015/859730.

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Ruthenium compounds are highly regarded as potential drug candidates. The compounds offer the potential of reduced toxicity and can be tolerated in vivo. The various oxidation states, different mechanism of action, and the ligand substitution kinetics of ruthenium compounds give them advantages over platinum-based complexes, thereby making them suitable for use in biological applications. Several studies have focused attention on the interaction between active ruthenium complexes and their possible biological targets. In this paper, we review several ruthenium compounds which reportedly posses
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4

Kanaoujiya, Rahul, and Shekhar Srivastava. "Coordination Chemistry of Ruthenium." Research Journal of Chemistry and Environment 25, no. 9 (2021): 103–6. http://dx.doi.org/10.25303/259rjce103106.

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Ruthenium is one of the rare elements that belongs to the platinum group metals. Ruthenium is very effective hardener for platinum and palladium. Well studied coordination and organometallic chemistry of ruthenium results in a various varieties of compounds. There are various features of ruthenium such as oxidation states, coordination numbers and geometries. Ruthenium compounds have various applications and also have low toxicity and they are ideal for the catalytic synthesis of drugs. The field of ruthenium chemistry is very broad and is extremely diverse in the field of catalysis and medici
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5

Allardyce, Claire S., and Paul J. Dyson. "Ruthenium in Medicine: Current Clinical Uses and Future Prospects." Platinum Metals Review 45, no. 2 (2001): 62–69. http://dx.doi.org/10.1595/003214001x4526269.

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There is no doubt about the success of precious metals in the clinic, with, for example, platinum compounds being widely used in the treatment of cancer, silver compounds being useful antimicrobial agents and gold compounds used routinely in the treatment of rheumatoid arthritis. The medicinal properties of the other platinum group metals are now being recognised and of these a ruthenium anticancer agent has recently entered the clinic, showing promising activity on otherwise resistant tumours. Like all metal drugs, the activity of the ruthenium compounds depends on both the oxidation state an
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6

Pobłocki, Kacper, Marta Pawlak, Juliusz Walczak, Joanna Drzeżdżon, and Dagmara Jacewicz. "WŁAŚCIWOŚCI KATALITYCZNE I BIOMEDYCZNE ZWIĄZKÓW ZAWIERAJĄCYCH JONY RUTENU(II) ORAZ RUTENU(III)." Wiadomości Chemiczne 77, no. 5 (2023): 569–95. https://doi.org/10.53584/wiadchem.2023.05.8.

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Ruthenium complexes appear in scientific publications mainly as catalysts in the olefins metathesis process. In this review, we want to indicate the research niche regarding the use of ruthenium(II) and ruthenium(III) complexes in other catalytic processes, i.e. polymerization or epoxidation of olefins and depolymerization. We would like to combine the catalytic properties of ruthenium(II,III) complex compounds with their biomedical activity due to the growing problem of drug resistance (including antibiotic resistance). Scientists have been designing new metallopharmaceuticals exhibiting biol
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7

Okawara, Toru, Masaaki Abe, Shiho Ashigara, and Yoshio Hisaeda. "Molecular structures, redox properties, and photosubstitution of ruthenium(II) carbonyl complexes of porphycene." Journal of Porphyrins and Phthalocyanines 19, no. 01-03 (2015): 233–41. http://dx.doi.org/10.1142/s1088424614501120.

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Two ruthenium(II) carbonyl complexes of porphycene, (carbonyl)(pyridine)(2,7,12,17-tetra-n-propylporphycenato)ruthenium(II) (1) and (carbonyl)(pyridine)(2,3,6,7,12,13,16,17-octaethylpor-phycenato)ruthenium(II) (2), have been structurally characterized by single-crystal X-ray diffraction analysis. Cyclic voltammetry has revealed that the porphycene complexes undergo multiple oxidations and reductions in dichloromethane and the reduction potentials are highly positive compared to porphyrin analogs. UV-light irradiation (400 nm or shorter wavelength region) of a benzene solution of 1 and 2 contai
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8

Houbrechts, Stephan, Carlo Boutton, Koen Clays, et al. "Novel Organometallic Compounds for Nonlinear Optics." Journal of Nonlinear Optical Physics & Materials 07, no. 01 (1998): 113–20. http://dx.doi.org/10.1142/s0218863598000090.

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Hyper-Rayleigh scattering is used to investigate the nonlinear optical properties of novel metal (ruthenium, nickel and gold) σ-arylacetylide complexes. The influence of the organometallic donor group and conjugating bridge on the quadratic hyperpolarizability is studied. For all organic ligands, the addition of the metal (donor) group is shown to increase the static hyperpolarizability by a factor of 2, 4 and 7 for gold, nickel and ruthenium complexes, respectively. Moreover, replacement of phenyl with a heterocyclic ring is demonstrated to enlarge the hyperpolarizability in the case of gold
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9

Zelen, Ivanka, Milan Zarić, Petar P. Čanović, Danica Igrutinović, and Ana Rilak Simović. "Antitumor activity of ruthenium(II) complexes on HCT 116 cell line in vitro." Education and Research in Health Sciences 1, no. 1 (2022): 6–12. http://dx.doi.org/10.5937/erhs2201006z.

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In the field of non-platinum complexes, ruthenium complexes have shown very strong antitumor activity on various types of cisplatin-resistant tumors. In addition, Ru(II) and Ru(III) complexes have shown a high degree of selectivity towards cancer cells as well as antimetastatic effects. Importantly, ruthenium compounds can bind to the DNA molecule of a tumor cell and thus reduce the viability of cancer cells. Moreover, ruthenium complexes can bind to human serum albumin and transferrin, which makes their transfer to tumor cells more efficient than platinum compounds. Consequently, the research
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10

MURAHASHI, Shun-Ichi, and Takeshi NAOTA. "Organic synthesis using ruthenium compounds." Journal of Synthetic Organic Chemistry, Japan 46, no. 10 (1988): 930–42. http://dx.doi.org/10.5059/yukigoseikyokaishi.46.930.

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11

Zahirović, Adnan, Irnesa Osmanković, Emir Turkušić, and Emira Kahrović. "Improved method for spectrophotometric determination of ruthenium using 1,10-phenanthroline: application for analysis of complex compounds." Analytical Methods 10, no. 42 (2018): 5078–83. http://dx.doi.org/10.1039/c8ay01755g.

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12

Ma, J. "Block by ruthenium red of the ryanodine-activated calcium release channel of skeletal muscle." Journal of General Physiology 102, no. 6 (1993): 1031–56. http://dx.doi.org/10.1085/jgp.102.6.1031.

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The effects of ruthenium red and the related compounds tetraamine palladium (4APd) and tetraamine platinum (4APt) were studied on the ryanodine activated Ca2+ release channel reconstituted in planar bilayers with the immunoaffinity purified ryanodine receptor. Ruthenium red, applied at submicromolar concentrations to the myoplasmic side (cis), induced an all-or-none flickery block of the ryanodine activated channel. The blocking effect was strongly voltage dependent, as large positive potentials that favored the movement of ruthenium red into the channel conduction pore produced stronger block
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13

Севостьянова, Н. Т., та С. А. Баташев. "Комплексы рутения в катализе реакций карбонилирования ненасыщенных соединений". Bulletin of Science and Practice 372, № 7(8) (2016): 14–19. https://doi.org/10.5281/zenodo.58042.

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Работа посвящена вопросу катализа реакций карбонилирования ненасыщенных соединений комплексами рутения. Целью работы являлась систематизация данных по многообразию комплексов рутения, проявляющих реакционную способность при взаимодействии с реагентами — участниками реакций карбонилирования. Литературный поиск выявил немного работ, содержащих детальное описание исследований каталитических комплексов рутения, участвующих в этих реакциях. Анализ работ показал, что рутений проявляет свойства активного комплексообразователя, образуя комплексы с N2, CO, органофосфинами, алкенами, алкинами
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14

de Sousa, Aurideia P., Ana C. S. Gondim, Eduardo H. S. Sousa, et al. "Biphosphinic ruthenium complexes as the promising antimicrobial agents." New Journal of Chemistry 44, no. 48 (2020): 21318–25. http://dx.doi.org/10.1039/d0nj03122d.

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There is an urgent need for new antimicrobial compounds to combat the growing threat of widespread antibiotic resistance. Ruthenium compounds have shown promising activities including two biphosphinic compounds as described here.
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15

Mondal, Ashaparna, and Priyankar Paira. "Synthesis and Biological Evaluations of Organoruthenium Scaffolds: A Comprehensive Update." Current Organic Synthesis 15, no. 2 (2018): 179–207. http://dx.doi.org/10.2174/1570179414666170703143049.

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Background: Currently ruthenium complexes are immerging as effective anticancer agents due to their less toxicity, better antiproliferative and antimetastatic activity, better stability in cellular environment and most importantly variable oxidation and co-ordination states of ruthenium allows binding this molecule with a variety of ligands. So in past few years researchers have shifted their interest towards organoruthenium complexes having good fluorescent profile that may be applicable for cancer theranostics. Nowadays, photodynamic therapy has become more acceptable because of its easy and
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16

Barna, Fabienne, Karim Debache, Carsten A. Vock, Tatiana Küster, and Andrew Hemphill. "In VitroEffects of Novel Ruthenium Complexes in Neospora caninum and Toxoplasma gondii Tachyzoites." Antimicrobial Agents and Chemotherapy 57, no. 11 (2013): 5747–54. http://dx.doi.org/10.1128/aac.02446-12.

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ABSTRACTUpon the screening of 16 antiproliferative compounds againstToxoplasma gondiiandNeospora caninum, two hydrolytically stable ruthenium complexes (compounds 16 and 18) exhibited 50% inhibitory concentrations of 18.7 and 41.1 nM (T. gondii) and 6.7 and 11.3 nM (N. caninum). To achieve parasiticidal activity with compound 16, long-term treatment (22 to 27 days at 80 to 160 nM) was required. Transmission electron microscopy demonstrated the rapid impact on and ultrastructural alterations in both parasites. These preliminary findings suggest that the potential of ruthenium-based compounds sh
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17

Nobel, N’guessan Kouakou, Niamké Jean Baptiste Kangah, Ehouman Jean Missa, et al. "Structure-activity Relationships of Substituted Ruthenium Azopyridine Complexes: A DFT and QSAR Study for Anticancer Applications." Chemical Science International Journal 34, no. 2 (2025): 70–85. https://doi.org/10.9734/csji/2025/v34i2958.

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The anarchic proliferation of cells in all types of organs in the human body leads to tumours called cancer. Chemotherapy remains an alternative treatment. Transition metal-based agents such as cisplatin have been shown to be effective. However, their use is hampered by unwanted side effects. One alternative to platinum is ruthenium. Ruthenium azopyridine complexes are promising anticancer agents for the treatment of certain cancers by chemotherapy. The aim of this work is to design ruthenium azopyridine complexes with enhanced cytotoxic activity. These compounds are all derived from δ-Cl isom
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18

Bratsos, Ioannis, Stephanie Jedner, Teresa Gianferrara, and Enzo Alessio. "Ruthenium Anticancer Compounds: Challenges and Expectations." CHIMIA International Journal for Chemistry 61, no. 11 (2007): 692–97. http://dx.doi.org/10.2533/chimia.2007.692.

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19

Marques da Silva Paula, Marcos, Claus Tröger Pich, Fabrícia Petronilho, et al. "Antioxidant activity of new ruthenium compounds." Redox Report 10, no. 3 (2005): 139–43. http://dx.doi.org/10.1179/135100005x38897.

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20

Steed, Jonathan W., and Derek A. Tocher. "Organometallic carboxylato compounds of ruthenium(IV)." Inorganica Chimica Acta 189, no. 2 (1991): 135–36. http://dx.doi.org/10.1016/s0020-1693(00)80179-6.

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21

Genet, Jean Pierre, Angela Marinetti, and Virginie Ratovelomanana-Vidal. "Recent advances in asymmetric catalysis. Synthetic applications to biologically active compounds." Pure and Applied Chemistry 73, no. 2 (2001): 299–303. http://dx.doi.org/10.1351/pac200173020299.

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New chiral cationic ruthenium complexes have been used for the industrial synthesis of (+) -dihydrojasmonate. A new class of electron-rich C2-symmetric 2,4-disubstituted phosphetanes (CnrPHOS) was developed. Preliminary evaluation of their catalytic properties revealed high efficiency in rhodium and ruthenium-catalyzed asymmetric hydrogenations. A new stereochemical model is presented in which the phosphetane Rh-catalyzed hydrogenation follows an apparent stability-controlled mechanism.
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22

Thakur, Rajesh K., Rasna Thakur, N. Kaurav, G. S. Okram, and N. K. Gaur. "Structural and Thermal Properties of YMn1-xRuxO3." Advanced Materials Research 975 (July 2014): 69–72. http://dx.doi.org/10.4028/www.scientific.net/amr.975.69.

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We report the structural and thermo-power measurement of the ruthenium doped YMnO3 compounds. The room temperature XRD study shows the single phase formation of the reported compounds with the incremental unit cell volume and lattice parameters attributed to the larger ionic radius of the Ru3+ (0.68 Å) and Ru4+ (0.62 Å) as compared with that of the Mn3+ (0.65 Å) Mn4+ (0.52 Å). The observed variation of lattice parameters provides us valuable information into the better consideration of the valence state of ruthenium, in these compounds. The thermo-power measurement reveals hole-like conduc
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23

Domínguez-Jurado, Elena, Francisco J. Cimas, José Antonio Castro-Osma, et al. "Tuning the Cytotoxicity of Bis-Phosphino-Amines Ruthenium(II) Para-Cymene Complexes for Clinical Development in Breast Cancer." Pharmaceutics 13, no. 10 (2021): 1559. http://dx.doi.org/10.3390/pharmaceutics13101559.

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Despite some limitations such as long-term side effects or the potential presence of intrinsic or acquired resistance, platinum compounds are key therapeutic components for the treatment of several solid tumors. To overcome these limitations, maintaining the same efficacy, organometallic ruthenium(II) compounds have been proposed as a viable alternative to platinum agents as they have a more favorable toxicity profile and represent an ideal template for both, high-throughput and rational drug design. To support the preclinical development of bis-phoshino-amine ruthenium compounds in the treatm
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24

Grigoreva, T. F., E. A. Pavlov, P. A. Vitiaz, and N. Z. Lyakhov. "Mechanochemical synthesis of intermetallic compounds in the system gallium – ruthenium." Chimica Techno Acta 8, no. 1 (2021): 20218104. http://dx.doi.org/10.15826/chimtech.2021.8.1.04.

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The interaction of a solid inert metal Ru with liquid active metal Ga during mechanical activation in a high-energy planetary ball mill was studied using the X-ray diffraction and the high resolution scanning electron microscopy with energy dispersive X-ray microanalyses. This paper considers mechanical activation effects on formation of intermetallic compounds GaxRuy and their solubility in concentrated acids. Gallium is a surface-active substance with respect to Ruthenium. Under intensive mechanical treatment, liquid Gallium penetrates into grain boundaries of polycrystalline Ruthenium parti
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Thiere, Alexandra, Hartmut Bombach, and Michael Stelter. "The Behavior of Ruthenium in Copper Electrowinning." Metals 12, no. 8 (2022): 1260. http://dx.doi.org/10.3390/met12081260.

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The recycling of material containing precious metals can lead to the entry of ruthenium into the copper electrowinning process, by so far unknown effects. There, ruthenium is oxidized to highly volatile ruthenium tetroxide. In order to avoid ruthenium losses during electrolysis, the oxidation behavior of ruthenium in copper electrowinning was investigated by testing different oxygen overvoltages using lead alloy and diamond anodes. Furthermore, the temperature and the current density were varied to investigate a possible chemical or electrochemical reaction. The results of the study show that
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26

Enow, Charles A., Charlene Marais, and Barend C. B. Bezuidenhoudt. "Catalytic epoxidation of stilbenes with non-peripherally alkyl substituted carbonyl ruthenium phthalocyanine complexes." Journal of Porphyrins and Phthalocyanines 16, no. 04 (2012): 403–12. http://dx.doi.org/10.1142/s1088424612500459.

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A number of novel carbonyl(1,4,8,11,15,18,22,25-octaalkylphthalocyaninato)-ruthenium(II) complexes were prepared by metal insertion with Ru3(CO)12. The new compounds have been characterized by1H NMR,13C NMR, IR, UV-vis and mass spectroscopy. This study demonstrated that this type of complexes and specifically carbonyl(1,4,8,11,15,18,22,25-octahexylphthalo-cyaninato)ruthenium(II) and carbonyl[1,4,8,11,15,18,22,25-octa(2-cyclohexylethyl)phthalocyaninato]-ruthenium(II), exhibit high catalytic activity and stability in the epoxidation of stilbenes with 2,6-dichloropyridine N-oxide as oxidant.
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27

Saha, Koushik, Urminder Kaur, Rosmita Borthakur та Sundargopal Ghosh. "Synthesis of Trithia-Borinane Complexes Stabilized in Diruthenium Core: [(Cp*Ru)2(η1-S)(η1-CS){(CH2)2S3BR}] (R = H or SMe)". Inorganics 7, № 2 (2019): 21. http://dx.doi.org/10.3390/inorganics7020021.

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The thermolysis of arachno-1 [(Cp*Ru)2(B3H8)(CS2H)] in the presence of tellurium powder yielded a series of ruthenium trithia-borinane complexes: [(Cp*Ru)2(η1-S)(η1-CS){(CH2)2S3BH}] 2, [(Cp*Ru)2(η1-S)(η1-CS){(CH2)2S3B(SMe)}] 3, and [(Cp*Ru)2(η1-S)(η1-CS){(CH2)2S3BH}] 4. Compounds 2–4 were considered as ruthenium trithia-borinane complexes, where the central six-membered ring {C2BS3} adopted a boat conformation. Compounds 2–4 were similar to our recently reported ruthenium diborinane complex [(Cp*Ru){(η2-SCHS)CH2S2(BH2)2}]. Unlike diborinane, where the central six-membered ring {CB2S3} adopted
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28

Gałczyńska, Katarzyna, Zuzanna Drulis-Kawa, and Michał Arabski. "Antitumor Activity of Pt(II), Ru(III) and Cu(II) Complexes." Molecules 25, no. 15 (2020): 3492. http://dx.doi.org/10.3390/molecules25153492.

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Metal complexes are currently potential therapeutic compounds. The acquisition of resistance by cancer cells or the effective elimination of cancer-affected cells necessitates a constant search for chemical compounds with specific biological activities. One alternative option is the transition metal complexes having potential as antitumor agents. Here, we present the current knowledge about the application of transition metal complexes bearing nickel(II), cobalt(II), copper(II), ruthenium(III), and ruthenium(IV). The cytotoxic properties of the above complexes causing apoptosis, autophagy, DNA
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29

Grawe, Gregory F., Katia M. Oliveira, Celisnolia M. Leite, et al. "Ruthenium(ii)-diphosphine complexes containing acylthiourea ligands are effective against lung and breast cancers." Dalton Transactions 51, no. 4 (2022): 1489–501. http://dx.doi.org/10.1039/d1dt02851k.

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30

Pfeffer, Michael G., Christian Pehlken, Robert Staehle, Dieter Sorsche, Carsten Streb, and Sven Rau. "Supramolecular activation of a molecular photocatalyst." Dalton Trans. 43, no. 35 (2014): 13307–15. http://dx.doi.org/10.1039/c4dt00761a.

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31

Bagh, Bidraha, and Douglas W. Stephan. "Half sandwich ruthenium(ii) hydrides: hydrogenation of terminal, internal, cyclic and functionalized olefins." Dalton Trans. 43, no. 41 (2014): 15638–45. http://dx.doi.org/10.1039/c4dt02407a.

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Ruthenium(ii) complexes 2b–e with the general formula RuCl<sub>2</sub>(p-cymene)(NHC) were reacted with Et<sub>3</sub>SiH to generate a series of ruthenium(ii) hydrides 5b–e. These compounds 5b–e are effective catalysts for the hydrogenation of terminal, internal and cyclic and functionalized olefins.
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32

Sánchez, Mateo I., Cristina Penas, M. Eugenio Vázquez, and José L. Mascareñas. "Metal-catalyzed uncaging of DNA-binding agents in living cells." Chem. Sci. 5, no. 5 (2014): 1901–7. http://dx.doi.org/10.1039/c3sc53317d.

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33

Czaban-Jóźwiak, Justyna, Łukasz Woźniak, Artur Ulikowski, Katarzyna Kwiecińska, Adam Rajkiewicz, and Karol Grela. "Modification of Polyhedral Oligomeric Silsesquioxanes (POSS) Molecules by Ruthenium Catalyzed Cross Metathesis." Molecules 23, no. 7 (2018): 1722. http://dx.doi.org/10.3390/molecules23071722.

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The scope of ruthenium (Ru)-catalyzed cross metathesis (CM) of allyl-decorated polyhedral oligomeric silsesquioxanes (POSS) was explored. A variety of different commercial and non-commercial ruthenium complexes were tested to determine that the nitro-activated Ru catalyst is optimal for this transformation. The reported transformation was used to prepare selected hybrid steroid-POSS compounds.
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34

Peña, Bruno, Amanda David, Christiane Pavani, et al. "Cytotoxicity Studies of Cyclometallated Ruthenium(II) Compounds: New Applications for Ruthenium Dyes." Organometallics 33, no. 5 (2014): 1100–1103. http://dx.doi.org/10.1021/om500001h.

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35

Barthelmes, Kevin, Andreas Winter, and Ulrich S. Schubert. "Hybrid materials based on ruthenium and fullerene assemblies." Dalton Transactions 45, no. 38 (2016): 14855–82. http://dx.doi.org/10.1039/c6dt02613c.

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36

Stein, Sebastian, Marcel Kersting, Lukas Heletta, and Rainer Pöttgen. "Rare earth-ruthenium-magnesium intermetallics." Zeitschrift für Naturforschung B 72, no. 6 (2017): 447–55. http://dx.doi.org/10.1515/znb-2017-0048.

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AbstractEight new intermetallic rare earth-ruthenium-magnesium compounds have been synthesized from the elements in sealed niobium ampoules using different annealing sequences in muffle furnaces. The compounds have been characterized by powder and single crystal X-ray diffraction. Sm9.2Ru6Mg17.8 (a=939.6(2), c=1779(1) pm), Gd11Ru6Mg16 (a=951.9(2), c=1756.8(8) pm), and Tb10.5Ru6Mg16.5 (a=942.5(1), c=1758.3(4) pm) crystallize with the tetragonal Nd9.34Ru6Mg17.66 type structure, space group I4/mmm. This structure exhibits a complex condensation pattern of square-prisms and square-antiprisms aroun
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37

Kanunnikova, Olga M., S. M. Reshetnikov, N. N. Chuchkova, and M. V. Smetanina. "Electrochemical Analysis of Magnesium Orotate Tautomers." Materials Science Forum 1087 (May 12, 2023): 67–73. http://dx.doi.org/10.4028/p-7x77uc.

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The oxide-ruthenium electrode is used for the analysis of oxygen-containing biologically active organic substances. This electrode can be recommended for the analysis of formic acid in dilute solutions (no more than 2 ml in 100 ml of solution). Due to the presence of two display potentials, the reliability of the determination of formic acid in solution is quite high. For the determination of nitrogen-containing compounds (urea), oxide-ruthenium electrodes are unsuitable. The obvious differences in the polarization curves of magnesium orotate tautomers indicate that the structural differences
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38

Fabijańska, Małgorzata, Maria M. Kasprzak, and Justyn Ochocki. "Ruthenium(II) and Platinum(II) Complexes with Biologically Active Aminoflavone Ligands Exhibit In Vitro Anticancer Activity." International Journal of Molecular Sciences 22, no. 14 (2021): 7568. http://dx.doi.org/10.3390/ijms22147568.

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Continuing our studies on the mechanisms underlying the cytotoxicity of potential drugs, we have described several aspects of the in vitro anticancer activity of ruthenium(II) and platinum(II) complexes with bioactive, synthetic aminoflavone ligands. We examined the mechanism of proapoptotic activity of cis-dichlorobis(3-imino-2-methoxyflavanone)ruthenium(II), cis-dichlorobis(3-imino-2-ethoxyflavanone)ruthenium(II), and trans-dichlorobis(3-aminoflavone)platinum(II). Cisplatin was used as a reference compound. The cytotoxicity was investigated by MTT assay. The mechanism of proapoptotic activit
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39

Studer, Valentin, Nicoleta Anghel, Oksana Desiatkina, et al. "Conjugates Containing Two and Three Trithiolato-Bridged Dinuclear Ruthenium(II)-Arene Units as In Vitro Antiparasitic and Anticancer Agents." Pharmaceuticals 13, no. 12 (2020): 471. http://dx.doi.org/10.3390/ph13120471.

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The synthesis, characterization, and in vitro antiparasitic and anticancer activity evaluation of new conjugates containing two and three dinuclear trithiolato-bridged ruthenium(II)-arene units are presented. Antiparasitic activity was evaluated using transgenic Toxoplasmagondii tachyzoites constitutively expressing β-galactosidase grown in human foreskin fibroblasts (HFF). The compounds inhibited T.gondii proliferation with IC50 values ranging from 90 to 539 nM, and seven derivatives displayed IC50 values lower than the reference compound pyrimethamine, which is currently used for treatment o
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40

Oliveira, Katia M., João Honorato, Guilherme R. Gonçalves, Marcia R. Cominetti, Alzir A. Batista, and Rodrigo S. Correa. "Ru(ii)/diclofenac-based complexes: DNA, BSA interaction and their anticancer evaluation against lung and breast tumor cells." Dalton Transactions 49, no. 36 (2020): 12643–52. http://dx.doi.org/10.1039/d0dt01591a.

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41

Gossens, Christian, Ivano Tavernelli, and Ursula Rothlisberger. "Rational Design of Organo-Ruthenium Anticancer Compounds." CHIMIA International Journal for Chemistry 59, no. 3 (2005): 81–84. http://dx.doi.org/10.2533/000942905777676795.

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42

Kanaoujiya, Rahul, Mukta Singh, Jyoti Singh, and Shekhar Srivastava. "Ruthenium Based Anticancer Compounds and Their Importance." Journal of scientific research 64, no. 01 (2020): 264–68. http://dx.doi.org/10.37398/jsr.2020.640150.

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43

Kobel, Wolfram, and Michael Hanack. "Bis axially coordinated (phthalocyaninato)ruthenium(II) compounds." Inorganic Chemistry 25, no. 1 (1986): 103–7. http://dx.doi.org/10.1021/ic00221a027.

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44

Kaithal, Akash, Basujit Chatterjee, and Chidambaram Gunanathan. "Ruthenium Catalyzed Selective Hydroboration of Carbonyl Compounds." Organic Letters 17, no. 19 (2015): 4790–93. http://dx.doi.org/10.1021/acs.orglett.5b02352.

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45

Lewis, Jack, and Paul R. Raithby. "Reflections on osmium and ruthenium carbonyl compounds." Journal of Organometallic Chemistry 500, no. 1-2 (1995): 227–37. http://dx.doi.org/10.1016/0022-328x(95)00512-o.

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46

Du Plessis, P. de V. "Electrical resistivity of rare earth ruthenium compounds." Physica B: Condensed Matter 163, no. 1-3 (1990): 603–5. http://dx.doi.org/10.1016/0921-4526(90)90282-y.

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47

Radulovic, S., S. Bjelogrlic, S. Arandjelovic, and Z. Tesic. "Antitumor activity of two ruthenium (Ru) compounds." Journal of Clinical Oncology 23, no. 16_suppl (2005): 2116. http://dx.doi.org/10.1200/jco.2005.23.16_suppl.2116.

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48

Mitsudo, Take-aki, Nobuyoshi Suzuki, Teruyuki Kondo, and Yoshihisa Watanabe. "Ruthenium Complex-Catalyzed Carbonylation of Allylic Compounds." Journal of Organic Chemistry 59, no. 25 (1994): 7759–65. http://dx.doi.org/10.1021/jo00104a036.

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49

Bora, Tankeswar, Meena Devi, and Pradip K. Gogoi. "Compounds of imidazoles with ruthenium(III) chloride." Transition Metal Chemistry 11, no. 12 (1986): 467–69. http://dx.doi.org/10.1007/bf01386878.

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50

Wohlers, M., B. Herzog, T. Belz, et al. "Ruthenium-C60 compounds: properties and catalytic potential." Synthetic Metals 77, no. 1-3 (1996): 55–58. http://dx.doi.org/10.1016/0379-6779(96)80057-9.

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