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1

Lowry, Sam. "Oregon Clips Measure 37's Wings." Planning & Environmental Law 60, no. 1 (January 2008): 9–10. http://dx.doi.org/10.1080/15480750802203213.

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2

Dries, D., J. Gramm, H. Lujan, and R. Gamelli. "37; TOXIC EPIDERMAL NECROLYSIS IN THE 90??s." SHOCK 1, Supplement (January 1994): 11. http://dx.doi.org/10.1097/00024382-199401001-00038.

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3

Kleidman, P. B., and A. J. E. Ryba. "Kostant′s Conjecture Holds for E7: L2(37)." Journal of Algebra 161, no. 2 (November 1993): 535–40. http://dx.doi.org/10.1006/jabr.1993.1234.

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4

Penna, Ivanna Marina. "Tectonism and erosion as conditioning factors for slope collapses in the Andean Cordillera (37-37°30′S)." Quaternary International 279-280 (November 2012): 374. http://dx.doi.org/10.1016/j.quaint.2012.08.1153.

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5

Pandorf, T., and R. Preuss. "S-37 In-Vivo like Testing of Ceramic Ball Heads." Journal of Biomechanics 43 (June 2010): S44. http://dx.doi.org/10.1016/s0021-9290(10)70090-7.

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6

Baltrus, PT, TE Raghunathan, and GA Kaplan. "#37-S race, socioeconomic position and long-term weight gain." Annals of Epidemiology 12, no. 7 (October 2002): 503–4. http://dx.doi.org/10.1016/s1047-2797(02)00325-3.

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7

Roberts, Rebecca L., Mary C. Wallace, Jill M. Drake, and Lisa K. Stamp. "Identification of a novel thiopurine S-methyltransferase allele (TPMT*37)." Pharmacogenetics and Genomics 24, no. 6 (June 2014): 320–23. http://dx.doi.org/10.1097/fpc.0000000000000049.

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8

Rehak, Katrin, Manfred R. Strecker, and Helmut P. Echtler. "Morphotectonic segmentation of an active forearc, 37°–41°S, Chile." Geomorphology 94, no. 1-2 (February 2008): 98–116. http://dx.doi.org/10.1016/j.geomorph.2007.05.002.

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9

Penna, I. M., R. L. Hermanns, S. Niedermann, and A. Folguera. "Multiple slope failures associated with neotectonic activity in the Southern Central Andes (37 -37 30'S), Patagonia, Argentina." Geological Society of America Bulletin 123, no. 9-10 (June 24, 2011): 1880–95. http://dx.doi.org/10.1130/b30399.1.

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10

Nivière, Bertrand, Grégoire Messager, Sébastien Carretier, and Pierre Lacan. "Geomorphic expression of the southern Central Andes forebulge (37°S, Argentina)." Terra Nova 25, no. 5 (April 27, 2013): 361–67. http://dx.doi.org/10.1111/ter.12044.

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11

Sharma, Prerana, Natalia Sharma, Priyasha Mishra, Joveeta Joseph, Dilip K. Mishra, Prashant Garg, and Sanhita Roy. "Differential Expression of Antimicrobial Peptides in Streptococcus pneumoniae Keratitis and STAT3-Dependent Expression of LL-37 by Streptococcus pneumoniae in Human Corneal Epithelial Cells." Pathogens 8, no. 1 (March 6, 2019): 31. http://dx.doi.org/10.3390/pathogens8010031.

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Streptococcus pneumoniae is the leading cause of bacterial keratitis in the developing world with a growing trend of acquiring resistance against various antibiotics. In the current study, we determined the expression of different antimicrobial peptides (AMPs) in response to S. pneumoniae in patients, as well as in primary and immortalized human corneal epithelial cells. We further focused on LL-37 and determined its expression in human cornea infected with S. pneumoniae and studied the killing ability of LL-37 against S. pneumoniae. The expression of AMPs was determined by quantitative PCR and the phosphorylation of signaling proteins was evaluated by immunoblot analysis. LL-37 expression was also determined by immunofluorescence and Western blot method and the killing ability of LL-37 against S. pneumoniae was determined by colony-forming units. Differential expression of antimicrobial peptides was observed in patients with S. pneumoniae keratitis. Although S. pneumoniae induced expression of the AMPs in human corneal epithelial cells (HCEC), it did not induce AMP expression in U937, a human monocyte cell line. S. pneumoniae also caused activation of nuclear factor kappa-light-chain enhancer of activated B cells (NF-κB)and mitogen activated protein kinase (MAPK) pathways in corneal epithelial cells. LL-37 was found to be effective against both laboratory and clinical strains of S. pneumoniae. LL-37 induction by S. pneumoniae in human corneal epithelial cells was mediated by signal transducer and activator of transcription 3 (STAT3) activation, and inhibition of STAT3 activation significantly reduced LL-37 expression. Our study determines an extensive profile of AMPs expressed in the human cornea during S. pneumoniae infection, and suggests the potential of LL-37 to be developed as an alternative therapeutic intervention to fight increasing antibiotic resistance among bacteria.
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12

Fennell, Lucas M., Sofia B. Iannelli, Alfonso Encinas, Maximiliano Naipauer, Victor Valencia, and Andrés Folguera. "Alternating contraction and extension in the Southern Central Andes (35°–37°S)." American Journal of Science 319, no. 5 (May 2019): 381–429. http://dx.doi.org/10.2475/05.2019.02.

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13

Melnick, D., B. Bookhagen, H. P. Echtler, and M. R. Strecker. "Coastal deformation and great subduction earthquakes, Isla Santa Maria, Chile (37 S)." Geological Society of America Bulletin 118, no. 11-12 (November 1, 2006): 1463–80. http://dx.doi.org/10.1130/b25865.1.

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14

Turienzo, Martín, Natalia Sánchez, Fernando Lebinson, Florencia Peralta, Vanesa Araujo, Ainara Irastorza, and Luis Dimieri. "Basement-cover interaction in the mountain front of the Northern Neuquén fold and thrust belt (37°10’ – 37°40’ S), Argentina." Journal of South American Earth Sciences 100 (June 2020): 102560. http://dx.doi.org/10.1016/j.jsames.2020.102560.

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15

Glodny, Johannes, Helmut Echtler, Santiago Collao, Mary Ardiles, Pablo Burón, and Oscar Figueroa. "Differential Late Paleozoic active margin evolution in South-Central Chile (37°S–40°S) – the Lanalhue Fault Zone." Journal of South American Earth Sciences 26, no. 4 (December 2008): 397–411. http://dx.doi.org/10.1016/j.jsames.2008.06.001.

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16

Saito, Hiro, Kengo Tachihara, Toshikazu Onishi, Nobuyuki Yamaguchi, Norikazu Mizuno, Akira Mizuno, Hideo Ogawa, and Yasuo Fukui. "A Study of the Molecular Cloud toward the H II Regions S 35 and S 37 with NANTEN." Publications of the Astronomical Society of Japan 51, no. 6 (December 1, 1999): 819–35. http://dx.doi.org/10.1093/pasj/51.6.819.

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17

Ezat, U., C. E. Lambert, and F. Dulac. "Composition of mineral aerosols from Amsterdam Island (37° S–77° E) and New Zealand (150° E–45° S)." Journal of Aerosol Science 26 (September 1995): S459—S460. http://dx.doi.org/10.1016/0021-8502(95)97137-4.

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18

Sieprawska-Lupa, Magdalena, Piotr Mydel, Katarzyna Krawczyk, Kinga Wójcik, Magdalena Puklo, Boguslaw Lupa, Piotr Suder, et al. "Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases." Antimicrobial Agents and Chemotherapy 48, no. 12 (December 2004): 4673–79. http://dx.doi.org/10.1128/aac.48.12.4673-4679.2004.

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ABSTRACT Cathelicidin LL-37 is one of the few human bactericidal peptides with potent antistaphylococcal activity. In this study we examined the susceptibility of LL-37 to proteolytic degradation by two major proteinases produced by Staphylococcus aureus, a metalloproteinase (aureolysin) and a glutamylendopeptidase (V8 protease). We found that aureolysin cleaved and inactivated LL-37 in a time- and concentration-dependent manner. Analysis of the generated fragments by mass spectroscopy revealed that the initial cleavage of LL-37 by aureolysin occurred between the Arg19-Ile20, Arg23-Ile24, and Leu31-Val32 peptide bonds, instantly annihilating the antibacterial activity of LL-37. In contrast, the V8 proteinase hydrolyzed efficiently only the Glu16-Phe17 peptide bond, rendering the C-terminal fragment refractory to further degradation. This fragment (termed LL-17-37) displayed antibacterial activity against S. aureus at a molar level similar to that of the full-length LL-37 peptide, indicating that the antibacterial activity of LL-37 resides in the C-terminal region. In keeping with LL-37 degradation by aureolysin, S. aureus strains that produce significant amounts of this metalloprotease were found to be less susceptible to LL-17-37 than strains expressing no aureolysin activity. Taken together, these data suggest that aureolysin production by S. aureus contributes to the resistance of this pathogen to the innate immune system of humans mediated by LL-37.
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19

Uhlmann, Julia, Manfred Rohde, Nikolai Siemens, Bernd Kreikemeyer, Peter Bergman, Linda Johansson, and Anna Norrby-Teglund. "LL-37 Triggers Formation of Streptococcus pyogenes Extracellular Vesicle-Like Structures with Immune Stimulatory Properties." Journal of Innate Immunity 8, no. 3 (December 8, 2015): 243–57. http://dx.doi.org/10.1159/000441896.

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Reports have shown that the antimicrobial peptide LL-37 is abundantly expressed but has limited bactericidal effect in Streptococcus pyogenes infections. At sub-inhibitory concentrations, LL-37 has been reported to alter virulence gene expression. Here, we explored the interaction of S. pyogenes strains with LL-37, focusing on bacterial growth, cell surface alterations and pro-inflammatory responses. Bioscreen turbidity measurements of strain 5448 cultured in the presence or absence of LL-37 confirmed the poor antimicrobial effect, and revealed a significant increase in turbidity of bacterial cultures exposed to sub-inhibitory concentrations of LL-37. However, this was not linked to increased bacterial counts. Electron microscopy of LL-37-exposed bacteria revealed the presence of vesicle-like structures on the bacterial surface. The vesicles stained positive for LL-37 and were released from the bacterial surface. Concentrated supernatants enriched in these structures had a broader protein content, including several virulence factors, compared to supernatants from untreated bacteria. The supernatants from LL-37-exposed bacteria were pro-inflammatory and elicited resistin and myeloperoxidase release from neutrophils. This is the first report on S. pyogenes extracellular vesicle-like structures formed at the bacterial surface in response to LL-37. The associated increased pro-inflammatory activity further implicates LL-37 as a potential factor involved in S. pyogenes pathogenesis.
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20

McCracken, Ellen, and Laura Demaria. "Argentina-s. Ricardo Piglia dialoga con la generacion del '37 en la discontinuidad." Hispanic Review 70, no. 2 (2002): 298. http://dx.doi.org/10.2307/3246927.

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21

Chen, Qiang, Hai-Ru Li, Wen-Juan Tian, Hai-Gang Lu, Hua-Jin Zhai, and Si-Dian Li. "Endohedral charge-transfer complex Ca@B37−: stabilization of a B373−borospherene trianion by metal-encapsulation." Physical Chemistry Chemical Physics 18, no. 21 (2016): 14186–90. http://dx.doi.org/10.1039/c6cp02369j.

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First-principles theory investigations present the possibility of an endohedralCsCa@B37which contains a 3D aromatic fullerene-likeCsB373−trianion composed of interwoven double chains.
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22

HALPIN-DOHNALEK, MARGARET I., and ELMER H. MARTH. "Growth of Staphylococcus aureus in Milks and Creams with Various Amounts of Milk Fat." Journal of Food Protection 52, no. 8 (August 1, 1989): 540–43. http://dx.doi.org/10.4315/0362-028x-52.8.540.

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Staphylococcus aureus strains 100-A, 196-E, 254, 473, 505, and 521 generally grew better in skim milk and whole milk (3.5% milk fat) than in light cream (18% milk fat) and heavy whipping cream (36% milk fat) at 25 and 37°C. S. aureus strains grew to greater than 106/ml from an inoculum of ca. 103/ml in skim and whole milk held at 37°C. From the same level of inoculum, strains grew to 106–107/ml in light cream held at 37°C. A 10 to 100-fold increase in population was observed for most strains in heavy whipping cream inoculated with ca. 104 S. aureus/ml and held at 37°C. Less than a 10-fold increase in population was noted for strain 254 in heavy whipping cream held at 37°C. When strains of S. aureus were inoculated into milks and creams and held at 25°C, populations of the pathogen increased approximately 100-fold in skim and whole milk and 10-fold or less in light cream and heavy whipping cream. S. aureus was enumerated using Chapman Stone, Mannitol Salt, Baird-Parker, and Vogel-Johnson agars; best results were obtained with Baird-Parker and Vogel-Johnson agars, particularly when high-fat fluid products were tested. Milk fat content, incubation temperature, and strain variation influenced the ability of S. aureus to grow in various dairy fluids.
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23

Ye, Z., C. Wang, A. Kijlstra, X. Zhou, and P. Yang. "A Possible Role for Interleukin 37 in the Pathogenesis of Behcet's Disease." Current Molecular Medicine 14, no. 4 (May 31, 2014): 535–42. http://dx.doi.org/10.2174/1566524014666140414210831.

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24

Sahin, Mustafa, Raziye Dut, Bernard Tahirbegolli, Sergen Devran, and Bulent Bayraktar. "S-37: Erkek Futbolcularda Bransa Ait Ozellikler, Atletik Performans Testleri ve Relatif Yas Etkisi." Turkish Journal of Sports Medicine 52, no. -1 (September 5, 2017): 37. http://dx.doi.org/10.5152/tjsm.2017.041.

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25

Hekinian, Roger, Peter Stoffers, Colin Devey, Dietrich Ackerman, Christophe Hémond, John O'Connor, Nicolas Binard, and Marcia Maia. "Intraplate versus ridge volcanism on the Pacific-Antarctic Ridge near 37°S-111°W." Journal of Geophysical Research: Solid Earth 102, B6 (June 10, 1997): 12265–86. http://dx.doi.org/10.1029/96jb03856.

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26

Sakuragi, Tadakazu, Hiroyuki Ishino, and Kenjiro Dan. "Bactericidal Activity of 0.5% Bupivacaine With Preservatives on Microorganisms in the Human Skin Flora." Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control 22, no. 2 (March 1997): 178–84. http://dx.doi.org/10.1136/rapm-00115550-199722020-00012.

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Background and ObjectivesThe bactericidal activity of 0.5% bupivacaine with preservatives at body temperature and at room temperature is not known. We studied the bactericidal activity of 0.5% bupivacaine with 0.08% methyl para-oxybenzoate and 0.02% propyl para-aminobenzoate as preservatives and of the preservatives alone at 37°C and at room temperature on two strains of methicillin-resistant Staphylococcus aureus, two strains of methicillin-susceptible S. aureus, and one strain each of Staphylococcus epidermidis and Escherichia coli. Methods. The pathogen was exposed to 0.5% bupivacaine with preservatives or to the preservatives alone for 1, 3, 6, 12, and 24 hours at 37°C and at room temperature. The inocula from these suspensions were cultured for 48 hours at 37°C after the antimicrobial activity of bupivacaine was inactivated by 1:1,000 dilution with physiological saline.ResultsThe 1- through 12-hour exposures of four strains of S. aureus to 0.5% bupivacaine with preservatives at room temperature reduced the mean colony count by 24.2%, 49.2%, 71.3%, and 89.6%, respectively, and the exposure at 37°C reduced the count by 74.1%, 95.2%, 99.9%, and 99.8%, respectively. The differences for 1- through 12-hour exposures were significant (P < .001). The percentage kill in the strains of E. coli and S. epidermidis was significantly higher than that in the strains of S. aureus at all exposure times at room temperature (E. coli, P < .001; S. epidermidis, P < .0001) and at 1- and 3-hour exposures at 37°C (E. coli, P < .001; S. epidermidis, P < .0001). The bactericidal activity of the preservatives was markedly lower that that of 0.5% bupivacaine with preservatives (P < .0001).ConclusionsThe bactericidal activity of 0.5% bupivacaine with preservatives is stronger at body temperature than at room temperature; the bactericidal activity may be due, to a large extent, to bupivacaine rather than to the preservatives; and S. aureus is more resistant to the bactericidal activity of bupivacaine than are S. epidermidis and E. coli.
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27

Reid, D. "A comparison of the yield responses of four grasses to a wide range of nitrogen application rates." Journal of Agricultural Science 105, no. 2 (October 1985): 381–87. http://dx.doi.org/10.1017/s0021859600056434.

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SUMMARYThe yield results are reported for an experiment in which 21 rates of nitrogen fertilizer were applied on pure-sown swards of four grasses, S. 24 and Barvestra perennial ryegrass, S. 37 cocksfoot and S. 53 meadow fescue. Growth curves fitted to the herbage yield data for each grass in each year are presented. On average the total dry-matter yield curves for the two ryegrasses were similar to one another, but showed a slightly smaller response to nitrogen rates below 300 kg/ha than did S. 23 ryegrass in an earlier experiment, and a more rapid decrease in response at higher rates. S. 37 cocksfoot had a similar dry-matter yield response to the ryegrasses at the low nitrogen rates, but the response decreased more rapidly at nitrogen rates over 250 kg/ha. The dry-matter yield response of S. 53 fescue decreased even more rapidly with nitrogen rates over 200 kg/ha. The mean estimates of the optimal nitrogen rate for each of the four grasses, i.e. the nitrogen rate at which the dry-matter response had decreased to 10 kg/kg N, was 380, 372, 357 and 327 kg N/ha for S. 24, Barvestra, S. 37 and S. 53 respectively, compared with 409 kg/ha for S. 23 ryegrass in the earlier experiment.
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28

Jovicich, Elio, Daniel J. Cantliffe, Peter J. Stoffella, and Dorota Z. Haman. "Bell Pepper Fruit Yield and Quality as Influenced by Solar Radiation-based Irrigation and Container Media in a Passively Ventilated Greenhouse." HortScience 42, no. 3 (June 2007): 642–52. http://dx.doi.org/10.21273/hortsci.42.3.642.

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Frequent fertigation of soilless-grown bell pepper (Capsicum annuum L.) can increase fruit production, but development of fruit disorders may offset the increase in yield of first-quality (blemish-free) fruit in greenhouses with minimal environmental control. Fruit yield and quality were studied as affected by water volumes and nutrient concentration levels, delivered with irrigation events initiated after determined cumulative solar radiation levels, in ‘HA3378’ bell pepper from October to May in north–central Florida. Irrigation events occurred after solar radiation integral levels (SRI; ±SD) 1.7 ± 0.42, 3.7 ± 0.42, 5.7 ± 0.42, 7.7 ± 0.42, and 9.7 ± 0.42 kW·min−1·m−2, which led to mean number of daily irrigation events of 61 ± 31, 26 ± 12, 17 ± 8, 12 ± 5, and 10 ± 4 respectively. In peat mix, perlite, and pine bark media, volume per irrigation event and concentration levels of the nutrient solution were, in the first experiment, 74 mL standard (74-s), and in a second concurrent experiment, 74 mL half-standard (74-½s) or 3) 37 mL standard (37-s). In both studies, combined marketable fruit yields of first quality and second quality (minor cracking patterns and yellow spots) increased linearly with decreasing SRI (increased events per day). First-quality fruit weight with 74-s was unaffected by media and, in a quadratic response to SRI, reached 5.4 kg·m−2 at 5.7 kW·min−1·m−2. First-quality weight with 74-½s and 37-s did not differ. Weight was unaffected by SRI in peat mix and perlite, and a quadratic response was recorded in pine bark, with yields of ≤3.6 kg·m−2. Fruit cracking incidence decreased with increased SRI, and was generally greater in pine bark. Incidence of yellow spots doubled with 74-½s compared with 37-s, and decreased linearly with increased SRI; the disorder was minor with 74-s. Compared with 37-s, 74-½s decreased fruit with blossom-end rot by 14%, increased marketable fruit weight by 10% in media with the lowest water-holding capacity (perlite, pine bark), and increased nutrient use efficiency. With any media used, the SRI set point of 5.7 kW·min−1·m−2 (daily mean of 17 irrigation events) and 74 mL, at standard nutrient concentration levels, appeared to produce greater blemish-free fruit yield than delivering 37 mL/event or half-concentrated 74 mL/event within the range of SRI means of 1.7 to 9.7 kW·min−1·m−2 (61–10 irrigation events/day). Disorder-tolerant pepper cultivars, better temperature control, and August plantings are additional suggestions for irrigation management to increase first-quality fruit yield.
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29

Soo, Po-Chi, Yu-Tze Horng, Jun-Rong Wei, Jwu-Ching Shu, Chia-Chen Lu, and Hsin-Chih Lai. "Regulation of Swarming Motility and flhDCSm Expression by RssAB Signaling in Serratia marcescens." Journal of Bacteriology 190, no. 7 (January 25, 2008): 2496–504. http://dx.doi.org/10.1128/jb.01670-07.

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ABSTRACT Serratia marcescens cells swarm at 30°C but not at 37°C, and the underlying mechanism is not characterized. Our previous studies had shown that a temperature upshift from 30 to 37°C reduced the expression levels of flhDCSm and hagSm in S. marcescens CH-1. Mutation in rssA or rssB, cognate genes that comprise a two-component system, also resulted in precocious swarming phenotypes at 37°C. To further characterize the underlying mechanism, in the present study, we report that expression of flhDCSm and synthesis of flagella are significantly increased in the rssA mutant strain at 37°C. Primer extension analysis for determination of the transcriptional start site(s) of flhDCSm revealed two transcriptional start sites, P1 and P2, in S. marcescens CH-1. Characterization of the phosphorylated RssB (RssB∼P) binding site by an electrophoretic mobility shift assay showed direct interaction of RssB∼P, but not unphosphorylated RssB [RssB(D51E)], with the P2 promoter region. A DNase I footprinting assay using a capillary electrophoresis approach further determined that the RssB∼P binding site is located between base pair positions −341 and −364 from the translation start codon ATG in the flhDCSm promoter region. The binding site overlaps with the P2 “−35” promoter region. A modified chromatin immunoprecipitation assay was subsequently performed to confirm that RssB∼P binds to the flhDCSm promoter region in vivo. In conclusion, our results indicated that activated RssA-RssB signaling directly inhibits flhDCSm promoter activity at 37°C. This inhibitory effect was comparatively alleviated at 30°C. This finding might explain, at least in part, the phenomenon of inhibition of S. marcescens swarming at 37°C.
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30

Cole, Daniel. "Heidegger and Social Ecology." Stance: an international undergraduate philosophy journal 1, no. 1 (September 6, 2019): 32–37. http://dx.doi.org/10.33043/s.1.1.32-37.

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In this essay I defend Heidegger’s critique of technology against possible criticisms that he may be an anti-humanist and a mystic. This essay will show that Heidegger’s critique of technology is helpful in thinking about ecological questions; and his contributions to such questions is relevant and not radically separated from some of the work of other philosophers today including Karen Warren and Marilyn Frye.
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31

Badovinatz, Eric. "There Are No Genuine Disagreements about Funniness." Stance: an international undergraduate philosophy journal 8, no. 1 (April 18, 2015): 29–37. http://dx.doi.org/10.33043/s.8.1.29-37.

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I argue that there are no genuine disagreements about whether something is funny. My argument rests largely on the premise that something is funny only if someone experiences it as funny. The bulk of this paper is spent supporting this premise, primarily through an analysis of the meaning of “funniness.” The rest of the paper is spent demonstrating how my conclusion follows from this premise.
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32

Neuhaus, H. "Screening for Colorectal Cancer in Germany: Guidelines and Reality." Endoscopy 31, no. 6 (August 1999): 468–70. http://dx.doi.org/10.1055/s-1999-37.

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33

Mesters, Rolf, José Fernández, Tilman Hackeng, Ryon Nakasone, John Griffin, and Mary Heeb. "Plasma protein S residues 37–50 mediate its binding to factor Va and inhibition of blood coagulation." Thrombosis and Haemostasis 110, no. 08 (2013): 275–82. http://dx.doi.org/10.1160/th12-12-0953.

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SummaryProtein S (PS) is an anticoagulant plasma protein whose deficiency is associated with increased risk of venous thrombosis. PS directly inhibits thrombin generation by the blood coagulation pathways by several mechanisms, including by binding coagulation factors (F) Va and Xa. To identify PS sequences that mediate inhibition of FVa activity, antibodies and synthetic peptides based on PS sequence were prepared and employed in plasma coagulation assays, purified component prothrombinase assays, binding assays, and immunoblots. In the absence of activated protein C, monoclonal antibody (Mab) S4 shortened FXa-induced clotting in normal plasma but not in PS-depleted plasma. Mab S4 also blocked PS inhibition of FVa-dependent prothrombinase activity in purified component assays in the absence or presence of phospholipids and inhibited binding of PS to immobilised FVa. Epitope mapping identified N-terminal region residues 37–67 of PS as this antibody’s epitope. A peptide representing PS residues 37–50 inhibited FVa-dependent prothrombinase activity in a noncompetitive manner, with 50% inhibition observed at 11 µM peptide, whereas a peptide with a D-amino acid sequence of 37–50 was ineffective. FVa, but not FXa, bound specifically to the immobilised peptide representing residues 37–50, and the peptide inhibited binding of FVa to immobilised PS. These data implicate PS residues 37–50 as a binding site for FVa that mediates, at least in part, the direct inhibition of FVa-dependent procoagulant activity by PS.
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34

Bello, Ramatu, Voon Chin, Mohammad Abd Rachman Isnadi, Roslaini Abd Majid, Maizaton Atmadini Abdullah, Tze Lee, Zainul Amiruddin Zakaria, Mohd Hussain, and Rusliza Basir. "The Role, Involvement and Function(s) of Interleukin-35 and Interleukin-37 in Disease Pathogenesis." International Journal of Molecular Sciences 19, no. 4 (April 11, 2018): 1149. http://dx.doi.org/10.3390/ijms19041149.

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35

Goll, B., and H. Zimmermann. "10 Gbit/s SiGe modulator driver with 37 dB gain and 680 mW power consumption." Electronics Letters 48, no. 15 (2012): 938. http://dx.doi.org/10.1049/el.2012.1548.

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36

Markgraf, Vera. "Paleoenvironmental Changes at the Northern Limit of the Subantarctic Nothofagus Forest, lat 37°S, Argentina." Quaternary Research 28, no. 1 (July 1987): 119–29. http://dx.doi.org/10.1016/0033-5894(87)90037-8.

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AbstractPaleoenvironmental changes dating back to before 10,000 yr B.P. at the northernmost occurrences of Nothofagus forests in Argentina at about latitude 37°S permit the reconstruction of past changes in the intensity of the winter rains, related to the southern westerlies that appear to determine the forest boundary. The paleoenvironmental interpretation is based on changes in the proportions of different Nothofagus species and changes in the ratio betwen forest and steppe taxa. The relatively most diverse and dense Nothofagus forest developed only during the last 4500 yr, prior to human impact during the last 300 yr. Before the middle Holocene, climatic conditions must have been different from the modern ones, with less overall precipitation judging from the overall lower amount of tree pollen and the reduction to primarily Nothfagus pumilio. An interval dated to older than 10,000 yr B.P. is characterized by co-occurrence of Prumnopitys andina, Nothofagus pumilio, and shrub-steppe taxa. Prumnopitys andina is known today only from scattered upper montane forest sites in Chile between 36° and 43°S lat and its ecological requirements are essentially unknown. The taxa combination, however, suggests that late-glacial climate must have been drier, and probably cooler than today. This implies that the winter rains and, consequently, the seasonal shift of the westerly circulation was reduced during the late Pleistocene and did not reach modern levels before 8500 yr B.P.
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Cicciarella Modica, Domenico, Massimo Maurici, Gian Loreto D’Alò, Cinzia Mozzetti, Alessandra Messina, Alessandra Distefano, Francesca Pica, and Patrizia De Filippis. "Taking Screenshots of the Invisible: A Study on Bacterial Contamination of Mobile Phones from University Students of Healthcare Professions in Rome, Italy." Microorganisms 8, no. 7 (July 19, 2020): 1075. http://dx.doi.org/10.3390/microorganisms8071075.

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Mobile phones (MPs) are commonly used both in the personal and professional life. We assessed microbiological contamination of MPs from 108 students in healthcare professions (HPs), in relation to their demographic characteristics and MPs handling habits, collected by means of a questionnaire. Cultural and biochemical tests were performed, and statistical analyses were carried out. Staphylococci were present in 85% of MPs, Enterococci in 37%, Coliforms in 6.5%; E. coli was never detected. Staphylococcus epidermidis was the most frequently isolated staphylococcal species (72% of MPs), followed by S. capitis (14%), S. saprophyticus, S. warneri, S. xylosus (6%), and by S. aureus (4%). Heterotrophic Plate Counts (HPC) at 37 °C, ranged from 0 to 1.2 × 104 CFU/dm2 (mean = 362 CFU/dm2). In univariate analysis, the male gender only was significantly associated with higher HPCs and enterococcal contamination. Multiple linear regression models explained only 17% and 16% of the HPC 37 °C and staphylococcal load variability, respectively. Developing specific guidelines for a hygienic use of MPs in clinical settings, for preventing cross-infection risks, is advisable, as well as introducing specific training programs to HP students. MPs decontamination procedures could also be implemented in the community.
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38

Zelus, Bruce D., Jeanne H. Schickli, Dianna M. Blau, Susan R. Weiss, and Kathryn V. Holmes. "Conformational Changes in the Spike Glycoprotein of Murine Coronavirus Are Induced at 37°C either by Soluble Murine CEACAM1 Receptors or by pH 8." Journal of Virology 77, no. 2 (January 15, 2003): 830–40. http://dx.doi.org/10.1128/jvi.77.2.830-840.2003.

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ABSTRACT The spike glycoprotein (S) of the murine coronavirus mouse hepatitis virus (MHV) binds to viral murine CEACAM receptor glycoproteins and causes membrane fusion. On virions, the 180-kDa S glycoprotein of the MHV-A59 strain can be cleaved by trypsin to form the 90-kDa N-terminal receptor-binding subunit (S1) and the 90-kDa membrane-anchored fusion subunit (S2). Incubation of virions with purified, soluble CEACAM1a receptor proteins at 37°C and pH 6.5 neutralizes virus infectivity (B. D. Zelus, D. R. Wessner, R. K. Williams, M. N. Pensiero, F. T. Phibbs, M. deSouza, G. S. Dveksler, and K. V. Holmes, J. Virol. 72:7237-7244, 1998). We used liposome flotation and protease sensitivity assays to investigate the mechanism of receptor-induced, temperature-dependent virus neutralization. After incubation with soluble receptor at 37°C and pH 6.5, virions became hydrophobic and bound to liposomes. Receptor binding induced a profound, apparently irreversible conformational change in S on the viral envelope that allowed S2, but not S1, to be degraded by trypsin at 4°C. Various murine CEACAM proteins triggered conformational changes in S on recombinant MHV strains expressing S glycoproteins of MHV-A59 or MHV-4 (MHV-JHM) with the same specificities as seen for virus neutralization and virus-receptor activities. Increased hydrophobicity of virions and conformational change in S2 of MHV-A59 could also be induced by incubating virions at pH 8 and 37°C, without soluble receptor. Surprisingly, the S protein of recombinant MHV-A59 virions with a mutation, H716D, that precluded cleavage between S1 and S2 could also be triggered to undergo a conformational change at 37°C by soluble receptor at neutral pH or by pH 8 alone. A novel 120-kDa subunit was formed following incubation of the receptor-triggered SA59H716D virions with trypsin at 4°C. The data show that unlike class 1 fusion glycoproteins of other enveloped viruses, the murine coronavirus S protein can be triggered to a membrane-binding conformation at 37°C either by soluble receptor at neutral pH or by alkaline pH alone, without requiring previous activation by cleavage between S1 and S2.
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39

Nitschke, Tobias, Philipp Groene, Alice-Christin Acevedo, Tobias Kammerer, and Simon T. Schäfer. "Coagulation under Mild Hypothermia Assessed by Thromboelastometry." Transfusion Medicine and Hemotherapy 48, no. 4 (2021): 203–9. http://dx.doi.org/10.1159/000513922.

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<b><i>Introduction:</i></b> While previous studies have shown a significant impact of extreme hypo- and hyperthermia on coagulation, effects of much more frequently occurring perioperative mild hypothermia are largely unknown. This study therefore aimed to analyze the effects of mild hypothermia using rotational thromboelastometry in vitro. <b><i>Materials and Methods:</i></b> Twelve healthy volunteers were included in this study. Standard thromboelastometric tests (EXTEM, INTEM, FIBTEM) were used to evaluate coagulation in vitro at 39, 37, 35.5, 35, and 33°C. Beyond standard thromboelastometric tests, we also evaluated the effects of mild hypothermia on the TPA-test (ClotPro, Enicor GmbH, Munich, Germany), a new test which aims to detect fibrinolytic capacity by adding tissue plasminogen activator to the sample. Data are presented as the median with 25/75th percentiles. <b><i>Results:</i></b> Extrinsically activated coagulation (measured by EXTEM) showed a significant increase in clot formation time (CFT; 37°C: 90 s [81/105] vs. 35°C: 109 s [99/126]; <i>p</i> = 0.0002), while maximum clot firmness (MCF) was not significantly reduced. Intrinsically activated coagulation (measured by INTEM) also showed a significant increase in CFT (37°C: 80 s [72/88] vs. 35°C: 94 s [86/109]; <i>p</i> = 0.0002) without significant effects on MCF. Mild hypothermia significantly increased both the lysis onset time (136 s [132/151; 37°C] vs. 162 s [141/228; 35°C], <i>p</i> = 0.0223) and lysis time (208 s [184/297; 37°C] vs. 249 s [215/358; 35°C]; <i>p</i> = 0.0259). <b><i>Conclusion:</i></b> This demonstrates that even under mild hypothermia coagulation is significantly altered in vitro. Perioperative temperature monitoring and management are greatly important and can help to prevent mild hypothermia and its adverse effects. Further investigation and in vivo testing of coagulation under mild hypothermia is needed.
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40

Faezah, S. S. M., F. M. Y. Zuraina, J. H. F. Farah, O. Khairul, N. I. Hilwani, M. I. Iswadi, C. N. Fang, I. Zawawi, O. M. Abas, and S. I. Fatimah. "The effects of magnetic separation on cryopreserved bovine spermatozoa motility, viability and cryo-capacitation status." Zygote 22, no. 3 (December 14, 2012): 378–86. http://dx.doi.org/10.1017/s0967199412000597.

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SummaryCryopreservation is a technique used to preserve cells for long-time storage. It is widely used in agriculture to store male gametes in liquid nitrogen. The aim of this study was to determine the optimum thawing temperature and time for samples subjected to annexin V magnetic-activated cell sorting (AnMACS) as the sperm preparation technique. Pooled semen samples from three ejaculates were divided into two groups. The treatment group was subjected both to AnMACS and to being cryopreserved, whilst the control group was cryopreserved directly without MACS. Post-thaw analysis was carried out for samples thawed at either 20°C for 13 s, 37°C for 30 s, 40°C for 7 s, 60°C for 6 s or 80°C for 5 s. Sperm kinematics, viability and capacitation status were determined for samples subjected to all thawing temperatures described. Results showed that thawing at 37°C for 13 s for MACS-processed samples was a superior option compared with other thawing procedures; there was a significant difference in P < 0.05 values for curvilinear velocity (VCL μm/s) and sperm straightness (STR %) when samples were thawed at 40°C for 7 s, with fewer capacitated spermatozoa (P < 0.05) when samples were thawed at 37°C for 30 s, 40°C for 7 s or 60°C for 6 s. Hence, we can speculate that the use of AnMACS as the sperm preparation technique can somehow enhance sperm cryosurvival rate after cryopreservation, however the fertilization potential of these cells has yet to be determined.
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41

Arlofa, N., M. Gozan, T. Pradita, and M. Jufri. "Optimization of Bioethanol Production from Durian Skin by Encapsulation of Saccharomyces cerevisiae." Asian Journal of Chemistry 31, no. 5 (March 28, 2019): 1027–33. http://dx.doi.org/10.14233/ajchem.2019.21751.

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The optimum condition of durian skin using SSF process with encapsulation of Saccharomyces cerevisiae takes place at pH 5.0 at 37 °C. S. cerevisiae encapsulation can increase bioethanol production activity. Bioethanol production is produced at pH 4.5; 5.0 and 5.5 were 35.85, 41.25 and 39.89 g/L medium, respectively. While using free cells S. cerevisiae, bioethanol produced was 21.42, 34.94 and 28.15 g/L medium. The percentage of bioethanol produced by S. cerevisiae was 15.3 % at pH 5.0; 40.25 % at pH 4.5 and 29.43 % at pH 5.5. Encapsulation of S. cerevisiae cells can increase the resistance to process temperature by differences in bioethanol production between encapsulation with cells free of S. cerevisiae by 19.34 % at 37 °C, 24.02 % at 40 °C and 49.01 % at 45 °C. These results are higher compared to cells free of S. cerevisiae.
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42

AIROLDI, A. A., and E. A. ZOTTOLA. "The Survival of Salmonella typhimurium in Propylene Glycol/Water Mixtures." Journal of Food Protection 52, no. 4 (April 1, 1989): 256–58. http://dx.doi.org/10.4315/0362-028x-52.4.256.

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The effect of propylene glycol, a coolant used in dairy processing plants, on the growth and survival of Salmonella typhimurium was studied. Cultures were inoculated into 0.1% reconstituted nonfat dry milk with glycol concentrations ranging from 0 to 50% (Aw 0.99-0.83) and were incubated at 37°C or −1°C. Serial dilutions were plated on tryptic soy agar (Difco), incubated at 37°C for 24 h and enumerated. At 37°C, 5% or more glycol inhibited the growth of S. typhimurium. At concentrations &gt;20% glycol, Aw&lt;0.96, no recovery was possible after 4 h at 37°C. At −1°C, a slow decline in population was seen regardless of glycol concentration. The higher the concentration, the faster the rate of decline in population. Aeration of the system resulted in a more rapid decrease in the number of S. typhimurium than the static system.
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43

Bezerra, José A. B., Andréia M. Silva, Patrícia C. Sousa, Lívia B. Campos, Érica C. G. Praxedes, Luana G. P. Bezerra, Thibério S. Castelo, Ana L. P. Souza, and Alexandre R. Silva. "Cryopreservation of collared peccary (Pecari tajacu L., 1758) epididymal sperm using extenders based on Tris and powdered coconut water (ACP®-116c)." Zygote 26, no. 4 (August 2018): 301–7. http://dx.doi.org/10.1017/s0967199418000230.

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SummaryThe aim of this study was to establish a functional freezing–thawing protocol for epididymal sperm of collared peccaries (Pecari tajacu L., 1758) by comparing different extenders. The epididymal sperm from 12 sexually mature males was recovered by retrograde flushing using Tris-based or coconut water-based (ACP®-116c) extenders. After initial evaluation, samples were diluted and frozen with the same extenders to which 20% egg yolk and 6% glycerol were added. After 2 weeks, thawing was performed at 37°C/60 s and sperm motility, vigour, morphology, functional membrane integrity, sperm viability, sperm plasma membrane integrity, and a computer-assisted semen analysis (CASA) were assessed. In addition, to evaluate the survival of frozen–thawed sperm, a thermal resistance test (TRT) was executed. Samples preserved using Tris were in better condition compared with those preserved using ACP®, showing higher values for most assessments performed, including CASA and the TRT (P<0.05). After determining Tris to be the better of the two extenders, additional samples were thawed using different thawing rates (37°C/60 s, 55°C/7 s, 70°C/8 s). Sperm thawed at 37°C/60 s had the greatest preservation (P<0.05) of viability (54.1 ± 5.9%) and functional membrane integrity (43.2 ± 5.4%), and had higher values for various CASA parameters. In conclusion, we suggest the use of a Tris-based extender added to egg yolk and glycerol for the cryopreservation of epididymal sperm obtained from collared peccaries. In order to achieve better post-thawing sperm quality, we suggest that samples should be thawed at 37°C/60 s.
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44

Stancu, Fl. "Corrigendum: Can Y(4140) be a $c\bar{c}s\bar{s}$ tetraquark? (2010 J. Phys. G: Nucl. Part. Phys. 37 075017)." Journal of Physics G: Nuclear and Particle Physics 46, no. 1 (November 27, 2018): 019501. http://dx.doi.org/10.1088/1361-6471/aaf026.

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45

Masucci, Maria Teresa, Antonella Petrillo, and Vincenzo Sica. "«4 S» Polycyclic Aromatic Hydrocarbon Binding Protein: Further Characterization and Kinetic Properties." Tumori Journal 73, no. 3 (June 1987): 237–47. http://dx.doi.org/10.1177/030089168707300306.

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A protein that binds polycyclic aromatic hydrocarbons (PAHs) with high affinity and sediments in a sucrose gradient at 4 S has been described in rat liver cytosol. This « 4 S » PAH binding protein precipitates at a 40–60% ammonium sulfate saturation. This partial purification procedure allows assay of this protein by using purified 3H-benzo(a)pyrene (3H-BaP) as radioactive ligand and dextran-coated charcoal as adsorbent for unreacted 3H-BaP. The 3H-BaP binding activity measured as a function of pH shows its maximum activity between pH 7.3 and 10.5. The « 4 S » PAH binding protein is stable up to 42 °C even in the absence of the ligand. At 65 °C the binding sites for 3H-BaP are destroyed. The binding activity assayed as a function of protein concentration is linear between 0.4 and 2 mg/ml at 0 °C, whereas at 37 °C higher protein concentrations (4 mg/ml) can be reached. Exposure to guanidine-HCl (3 M) and urea (5 M) for 20 min at 4 °C inhibits the PAH binding completely to the « 4 S » protein. Quick dilution or dialysis does not restore the binding activity. The dissociation rate of the « 4 S » PAH binding protein measured in the presence of an excess of unlabeled ligand at 0 °C is biphasic and shows a two-step, first-order kinetic pattern. At 37 °C the dissociation rate is linear and faster, and is complete after 5 min of incubation. The association rate shows the same behavior: the binding is complete after 10 min at 0 °C, whereas at 37 °C the reaction is 10 times as fast. The dissociation equilibrium constants at 0 °C and 37 °C are respectively 2.45 × 10−9 M and 1.09×10−9 M. The high rates of association and dissociation of BaP to « 4 S » PAH binding protein were used to set up an assay to exchange radioactive 3H-BaP with cold BaP.
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Hashimoto, Makoto, Takuma Yoshida, Zetryana Puteri Tachrim, Yasuko Sakihama, Yasuyuki Hashidoko, Yasumaru Hatanaka, and Yuichi Kanaoka. "Synthesis of Photophore and Fluorophore Modified O-Benzylserine Derivatives." HETEROCYCLES 95, no. 1 (2017): 462. http://dx.doi.org/10.3987/com-16-s(s)37.

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47

A. Soderquist, John, Buddy Soto-Cairoli, Iveliz Kock, Guang Yang, Jorge Justo de Pomar, José M. Guzmán, Javier R. González, and Augie Antomattei. "Selective Triisopropylsilylation of α-Amino Acids: Protection without Racemization." HETEROCYCLES 80, no. 1 (2010): 409. http://dx.doi.org/10.3987/com-09-s(s)37.

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48

Sheng, Ouwei, Chengbin Jin, Jianmin Luo, Huadong Yuan, Cong Fang, Hui Huang, Yongping Gan, et al. "Ionic conductivity promotion of polymer electrolyte with ionic liquid grafted oxides for all-solid-state lithium–sulfur batteries." Journal of Materials Chemistry A 5, no. 25 (2017): 12934–42. http://dx.doi.org/10.1039/c7ta03699j.

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49

Maruo, Ivan Toshio, Juliana Godoy-Bezerra, Armando Yukio Saga, Orlando Motohiro Tanaka, Hiroshi Maruo, and Elisa Souza Camargo. "Effect of etching and light-curing time on the shear bond strength of a resin-modified glass ionomer cement." Brazilian Dental Journal 21, no. 6 (2010): 533–37. http://dx.doi.org/10.1590/s0103-64402010000600009.

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The aim of this study was to assess the influence of etching and light-curing time on the shear bond strength (SBS) and adhesive remnant index (ARI) of a resin-modified glass ionomer cement (RMGIC) upon debonding of orthodontic brackets. Sixty-eight bovine permanent incisors were obtained and embedded in acrylic resin. Edgewise metallic brackets were bonded to the teeth with Fuji Ortho LC RMGIC. The specimens were randomly assigned to 4 groups, using the following etching and light-curing times: G1: 10% polyacrylic acid and 40 s (control); G2: 37% phosphoric acid and 40 s; G3: 10% polyacrylic acid and 50 s; and G4: 37% phosphoric acid and 50 s. Shear test was performed at 0.5 mm/min and the ARI was assessed. G2 (3.6 ± 0.98 MPa) presented significantly higher (p<0.05) SBS than G1 (2.76 ± 0.86 MPa) and G4 (2.86 ± 0.68 MPa), and there was no statistically significant difference (p>0.05) between G2 and G3 (2.94 ± 0.67 MPa). ARI presented prevalence of scores 2 and 3 in all groups. RMGIC SBS enhanced with 37% phosphoric acid etching and 40 s light-curing time, but this did not occur when the light-curing time was increased, regardless of the acid used. RMGIC presented prevalence of failures at the adhesive/bracket interface.
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50

Zhao, Yapei, Tian Hu, Ruiqi Liu, Zhiqiang Hao, Guoyan Liang, and Guanglin Li. "Biochemical Characterization and Function of Eight Microbial Type Terpene Synthases from Lycophyte Selaginella moellendorffii." International Journal of Molecular Sciences 22, no. 2 (January 9, 2021): 605. http://dx.doi.org/10.3390/ijms22020605.

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Selaginella moellendorffii is a lycophyte, a member of an ancient vascular plant lineage. Two distinct types of terpene synthase (TPS) genes were identified from this species, including S. moellendorffii TPS genes (SmTPSs) and S. moellendorffii microbial TPS-like genes (SmMTPSLs). The goal of this study was to investigate the biochemical functions of SmMTPSLs. Here, eight full-length SmMTPSL genes (SmMTPSL5, -15, -19, -23, -33, -37, -46, and -47) were functionally characterized from S. moellendorffii. Escherichia coli-expressed recombinant SmMTPSLs were tested for monoterpenes synthase and sesquiterpenes synthase activities. These enzymatic products were typical monoterpenes and sesquiterpenes that have been previous shown to be generated by typical plant TPSs when provided with geranyl diphosphate (GPP) and farnesyl diphosphate (FPP) as the substrates. Meanwhile, SmMTPSL23, -33, and -37 were up-regulated when induced by alamethicin (ALA) and methyl jasmonate (MeJA), suggesting a role for these genes in plants response to abiotic stresses. Furthermore, this study pointed out that the terpenoids products of SmMTPSL23, -33, and -37 have an antibacterial effect on Pseudomonas syringae pv. tomato DC3000 and Staphylococcus aureus. Taken together, these results provide more information about the catalytic and biochemical function of SmMTPSLs in S. moellendorffii plants.
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