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Journal articles on the topic 'S-SAD'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Hasegawa, T., та A. Yamano. "Sulfur SAD (S-SAD) phasing using CoKα radiation". Acta Crystallographica Section A Foundations of Crystallography 64, a1 (2008): C203. http://dx.doi.org/10.1107/s0108767308093495.

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Axelsson, Jóhann, Jón G. Stefánsson, Andrés Magnússon, Helgi Sigvaldason, and Mikael M. Karlsson. "Seasonal Affective Disorders: Relevance of Icelandic and Icelandic-Canadian Evidence to Etiologic Hypotheses." Canadian Journal of Psychiatry 47, no. 2 (2002): 153–58. http://dx.doi.org/10.1177/070674370204700205.

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Objective: This study tests the suggestion of earlier studies concerning the importance of genetic factors in the etiology of win ter seasonal affective disorders (SADs) and sub syndromal win ter SAD (S- SAD). Method: Two study populations of Winnipeg, Manitoba residents were canvassed: 250 adults of wholly Icelandic de scent and 1000 adults of non-Icelandic de scent. We distributed the Seasonal Pattern Assessment Questionnaire by mail to these 2 populations, yielding 204 and 449 valid responses, respectively. Results: Rates of SAD and S- SAD proved markedly lower in the Icelandic population t

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Yang, C., H. Fan, X. Su та ін. "In-house S-SAD and Se-SAD phasing with Cr-Kα radiation". Acta Crystallographica Section A Foundations of Crystallography 61, a1 (2005): c155. http://dx.doi.org/10.1107/s0108767305093426.

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4

Akram, Faisal, Tyler B. Jennings, John W. Stiller, Christopher A. Lowry, and Teodor T. Postolache. "Mood Worsening on Days with High Pollen Counts is associated with a Summer Pattern of Seasonality." Pteridines 30, no. 1 (2019): 133–41. http://dx.doi.org/10.1515/pteridines-2019-0016.

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Abstract Background: Summer/spring-type seasonal affective disorder (S-SAD) is the less common subtype of seasonal affective disorder and evidence regarding potential triggers of S-SAD is scarce. Recent reports support association of airborne-pollen with seasonal exacerbation of depression (mood seasonality) and timing of suicidal behavior. Therefore, we hypothesized that Old Order Amish (OOA) with summer/spring pattern of seasonality (abbreviated as summer pattern) and S-SAD will have significant mood worsening on high pollen days. Methods: A seasonal pattern of mood worsening and SAD paramet

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5

Lemke, Christopher T., G. David Smith та P. Lynne Howell. "S-SAD, Se-SAD and S/Se-SIRAS using Cu Kα radiation: why wait for synchrotron time?" Acta Crystallographica Section D Biological Crystallography 58, № 12 (2002): 2096–101. http://dx.doi.org/10.1107/s0907444902018838.

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Volkov, Janna, Kelly J. Rohan, Samina M. Yousufi, et al. "Seasonal Changes in Sleep Duration in African American and African College Students Living In Washington, D.C." Scientific World JOURNAL 7 (2007): 880–87. http://dx.doi.org/10.1100/tsw.2007.128.

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Duration of nocturnal melatonin secretion, a marker of “biological night” that relates to sleep duration, is longer in winter than in summer in patients with seasonal affective disorder (SAD), but not in healthy controls. In this study of African and African American college students, we hypothesized that students who met criteria for winter SAD or subsyndromal SAD (S-SAD) would report sleeping longer in winter than in summer. In addition, based on our previous observation that Africans report more “problems” with change in seasons than African Americans, we expected that the seasonal changes

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7

Gourhant, Patrick, Beatriz Guimaraes, Tatiana Isabet, et al. "S-SAD phasing on SOLEIL Beamline PROXIMA 1." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C609. http://dx.doi.org/10.1107/s2053273314093905.

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"PROXIMA 1, a beamline for macro-molecular crystallography at the 3rd generation synchrotron source SOLEIL, is equipped with a multi-circle goniometer (alpha 50 degrees) as well as a PILATUS 6M detector. These features, along with the extended energy range of the beam line towards the low energies (down to 5.5 keV) and the possibility to adapt the source size to the sample in order to optimize signal to noise ratio, have made the beam line very attractive for S-SAD phasing with more than seven examples of successful de novo phasing achieved over the last two years. The use of low energies has

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8

Wang, B. C., and J. P. Rose. "Recent efforts on phase determination by S-SAD." Acta Crystallographica Section A Foundations of Crystallography 67, a1 (2011): C64. http://dx.doi.org/10.1107/s0108767311098473.

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Soriano, Joseph J., Constantin Ciupagea, Kelly J. Rohan, et al. "Seasonal Variations in Mood and Behavior in Romanian Postgraduate Students." Scientific World JOURNAL 7 (2007): 870–79. http://dx.doi.org/10.1100/tsw.2007.127.

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To our knowledge, this paper is the first to estimate seasonality of mood in a predominantly Caucasian sample, living in areas with hot summers and a relative unavailability of air conditioning. As a summer pattern of seasonal depression was previously associated with a vulnerability to heat exposure, we hypothesized that those with access to air conditioners would have a lower rate of summer seasonal affective disorder (SAD) compared to those without air conditioning. A convenience sample of 476 Romanian postgraduate students completed the Seasonal Pattern Assessment Questionnaire (SPAQ), whi

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10

Melrose, Sherri. "Seasonal Affective Disorder: An Overview of Assessment and Treatment Approaches." Depression Research and Treatment 2015 (2015): 1–6. http://dx.doi.org/10.1155/2015/178564.

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Seasonal affective disorder or SAD is a recurrent major depressive disorder with a seasonal pattern usually beginning in fall and continuing into winter months. A subsyndromal type of SAD, or S-SAD, is commonly known as “winter blues.” Less often, SAD causes depression in the spring or early summer. Symptoms center on sad mood and low energy. Those most at risk are female, are younger, live far from the equator, and have family histories of depression, bipolar disorder, or SAD. Screening instruments include the Seasonal Pattern Assessment Questionnaire (SPAQ). Typical treatment includes antide

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11

Pundir, Sumit, Mohammad Wazid, Devesh Pratap Singh, Ashok Kumar Das, Joel J. P. C. J. P. C. Rodrigues, and Youngho Park. "Designing Efficient Sinkhole Attack Detection Mechanism in Edge-Based IoT Deployment." Sensors 20, no. 5 (2020): 1300. http://dx.doi.org/10.3390/s20051300.

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The sinkhole attack in an edge-based Internet of Things (IoT) environment (EIoT) can devastate and ruin the whole functioning of the communication. The sinkhole attacker nodes ( S H A s) have some properties (for example, they first attract the other normal nodes for the shortest path to the destination and when normal nodes initiate the process of sending their packets through that path (i.e., via S H A ), the attacker nodes start disrupting the traffic flow of the network). In the presence of S H A s, the destination (for example, sink node i.e., gateway/base station) does not receive the re

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Parisi, Maria Cândida R., Denise E. Zantut-Wittmann, Elizabeth J. Pavin, Helymar Machado, Márcia Nery, and William J. Jeffcoate. "Comparison of three systems of classification in predicting the outcome of diabetic foot ulcers in a Brazilian population." European Journal of Endocrinology 159, no. 4 (2008): 417–22. http://dx.doi.org/10.1530/eje-07-0841.

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ObjectiveThe aim was to compare three ulcer classification systems as predictors of the outcome of diabetic foot ulcers: the Wagner, the University of Texas (UT) and the size (area, depth), sepsis, arteriopathy, denervation system (S(AD)SAD) systems in a specialist clinic in Brazil.MethodsUlcer area, depth, appearance, infection and associated ischaemia and neuropathy were recorded in a consecutive series of 94 subjects. A novel score, the S(AD)SAD score, was derived from the sum of individual items of the S(AD)SAD system, and was evaluated. Follow-up was for at least 6 months. The primary out

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Jeskey, Jack, Akash Parida, Kelsey Graven, and Robert Hostoffer. "Specific Antibody Immunodeficiency Presenting With Streptococcal pneumonia-Induced Spontaneous Bacterial Peritonitis." Allergy & Rhinology 11 (January 2020): 215265672092806. http://dx.doi.org/10.1177/2152656720928065.

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Specific antibody immunodeficiency (SAD) is a primary immunodeficiency disorder characterized by normal levels of serum immunoglobulins (IgG, IgA, and IgM) associated with a dysfunctional immune response. SAD is associated with recurrent infections in the setting of an insufficient response to polysaccharide vaccinations. Streptococcus pneumoniae is a well-established cause of respiratory infections in SAD. However, there has been a paucity of evidence of pneumococcal peritonitis in SAD patients, being reported as spontaneous in acquired immunodeficiency such as AIDS. We report the first case

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Sim, Jacqueline Xiu Ling, Geoffrey Haw Chieh Liew, Hairil Abdullah, Theodore Gar Ling Wong, and Patrick Wong. "Low skill fibreoptic intubation using i-gel™ and air-Q™ in simulated difficult airways: A randomised study in manikin and in patients." Proceedings of Singapore Healthcare 29, no. 3 (2020): 156–62. http://dx.doi.org/10.1177/2010105820929049.

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Background: Fibreoptic intubation via a supraglottic device (SAD) is ‘low skill fibreoptic intubation’ (LSFOI). ‘Standard’ second generation SADs (i-gelTM) have a gastric port. ‘Specialised’ second generation SADs (air-QTM) are designed to facilitate LSFOI and have wider ventilation ports. Our hypothesis was that performance of LSFOI differs between i-gelTM and air-QTM in a manikin with a simulated difficult airway. Methods: Our primary outcome was fibreoptic intubation success rate. Our secondary outcomes included SAD insertion and LSFOI times. A difficult airway was simulated by applying a h

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15

Belrhali, Hassan, Akim Khadrouche, Babu Manjasetty, and Trevor Mairs. "Experimenting S-SAD on BM14-2 at the ESRF." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C606. http://dx.doi.org/10.1107/s2053273314093930.

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Bending Magnet beamline 14 (BM14) at the European Synchrotron Radiation Facility (ESRF, Grenoble, France) is dedicated to macromolecular crystallography (MX). This experimental station has been designed specifically to produce MX diffraction data using the methods of Single- or Multiple-wavelength Anomalous Diffraction (SAD or MAD) (www.bm14.eu). From 1994 to 2000, BM14 operated as an ESRF public beamline. Then from 2001 to 2009 the beamline was acquired and operated as an UK Medical Research Council Collaborative Research Group beamline. Since 2010, it is now back an ESRF beamline operated by

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16

Gessmann, Renate, Maria Papadovasilaki, Evangelos Drougkas, and Kyriacos Petratos. "Zinc-substituted pseudoazurin solved by S/Zn-SAD phasing." Acta Crystallographica Section F Structural Biology Communications 71, no. 1 (2015): 19–23. http://dx.doi.org/10.1107/s2053230x14025552.

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The copper(II) centre of the blue copper protein pseudoazurin fromAlcaligenes faecalishas been substituted by zinc(II)viadenaturing the protein, chelation and removal of copper and refolding the apoprotein, followed by the addition of an aqueous solution of ZnCl2. Vapour-diffusion experiments produced colourless hexagonal crystals (space groupP65), which when cryocooled had unit-cell parametersa=b= 49.01,c= 98.08 Å. Diffraction data collected at 100 K using a copper sealed tube were phased by the weak anomalous signal of five S atoms and one Zn atom. The structure was fitted manually and refin

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De Franceschi, L., Y. Beuzard, and C. Brugnara. "Sulfhydryl oxidation and activation of red cell K(+)-Cl- cotransport in the transgenic SAD mouse." American Journal of Physiology-Cell Physiology 269, no. 4 (1995): C899—C906. http://dx.doi.org/10.1152/ajpcell.1995.269.4.c899.

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The SAD mouse is characterized by the expression of human SAD hemoglobin (Hb), a super S Hb with a higher tendency to polymerize than HbS due to the presence of two additional mutations, Antilles beta 23Ile and D Punjab beta 121Glu. Monovalent cation transport was studied in erythrocytes from SAD-1 (Hb SAD = 19%) and beta-thal/SAD-1 (Hb SAD = 26%) mice. Erythrocytes containing Hb SAD exhibited dehydration, increased maximal rate of Na(+)-K+ pump, unchanged Rb+ flux via the Gardos channel, and increased K(+)-Cl- cotransport. K(+)-Cl- cotransport was defined as Cl(-)-dependent (substitution with

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18

Halberstadt, Jamin B., Paula M. Niedenthal, and Julia Kushner. "Resolution of Lexical Ambiguity by Emotional State." Psychological Science 6, no. 5 (1995): 278–82. http://dx.doi.org/10.1111/j.1467-9280.1995.tb00511.x.

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The role of emotion in the resolution of lexical ambiguity was investigated Happy and sad subjects listened to a list of words that included homophones that had happy and neutral meanings (e g, presents-presence) and homophones that had sad and neutral meanings (e g, mourning-morning) Words were presented every 3 s, and subjects wrote down the words as they heard them (Meaning could be identified by spelling in all cases) An interaction between emotional state and homophone category was observed Sad subjects were more likely to write down sad meanings than were happy subjects Results are discu

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Holy, Mirela, Nikolina Borčić, and Diana Tomić. "Analiza odabranih članaka o napadu kemijskim oružjem u Siriji u hrvatskim i njemačkim elektroničkim medijima." Medijska istraživanja 25, no. 1 (2019): 5–31. http://dx.doi.org/10.22572/mi.25.1.1.

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Rat u Siriji velika je prijetnja globalnoj sigurnosti, prepleteno polje vitalnih geopolitičkih interesa najvažnijih svjetskih sila – SAD-a i Rusije te njihovih saveznika. Rusija se politički i vojno pozicionirala na strani režima sirijskog predsjednika al-Assada protiv pobunjenika, dok je pozicija SAD-a i članica NATO-a ambivalentna. Osuđuje se nedemokratski režim sirijskog predsjednika i zahtijeva njegov opoziv te se istovremeno osuđuje teroristička prijetnja ISIS-a koji se stopio sa sirijskim pobunjeničkim pokretom. Korištenje kemijskog oružja u Siriji u travnju 2017. prijetilo je eskalacijo

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Cherniak, A. V., O. I. Savushkina, T. L. Pashkova, and E. V. Kryukov. "Diagnosis of small airway dysfunction in patients with chronic obstructive pulmonary disease." Almanac of Clinical Medicine 48, no. 5 (2020): 307–15. http://dx.doi.org/10.18786/2072-0505-2020-48-019.

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Background: Small airway dysfunction (SAD) is a functional hallmark of chronic obstructive pulmonary disease (COPD). However, SAD prevalence and its role in COPD pathophysiology are not yet sufficiently studied.Background: Small airway dysfunction (SAD) is a functional hallmark of chronic obstructive pulmonary disease (COPD). However, SAD prevalence and its role in COPD pathophysiology are not yet sufficiently studied.Aim: To assess the prevalence of SAD in COPD patients by various functional diagnostic methods, such as spirometry, body plethysmography, and impulse oscillometry (IOS).Materials

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Liebschner, Dorothee, Naohiro Matsugaki, Miki Senda, Yusuke Yamada, and Toshiya Senda. "Softer but stronger? Sulfur SAD with low energy X-rays of 2.7 Å." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C604. http://dx.doi.org/10.1107/s2053273314093954.

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Single wavelength anomalous diffraction (SAD) is a powerful experimental phasing technique used in macromolecular crystallography (MX). SAD is based on the absorption of X-rays by heavy atoms, which can be either incorporated into the protein (crystal) or naturally present in the structure, such as sulfur or metal ions. In particular, sulfur seems to be an attractive candidate for phasing, because most proteins contain a considerable number of S atoms. However, the K-absorption edge of sulfur is around 5.1 Å wavelength (2.4 keV), which is far from the optimal wavelength of most MX-beamlines at

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Abe, Chikara, and Hironobu Morita. "Drinking-induced bradyarrhythmias and cerebral injury in Dahl salt-sensitive rats with sinoaortic denervation." Journal of Applied Physiology 115, no. 10 (2013): 1533–39. http://dx.doi.org/10.1152/japplphysiol.00866.2013.

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We have demonstrated that a drinking-induced pressor response was larger if the baroreflex did not operate, and the mean arterial pressure reached 163 mmHg in conscious rats with sinoaortic denervation (SAD). Thus we hypothesized that a drinking behavior became a cardiovascular risk factor if a basal arterial pressure was high. To clarify this, we analyzed the occurrence of arrhythmias and the accumulation of microglia in Dahl salt-sensitive rats (Dahl S) with SAD. We maintained Dahl S and Dahl salt-resistant rats (Dahl R) with a high-sodium diet for 5 weeks. After SAD surgery, we measured art

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Barbosa, Joana, José Ignácio Guinaldo Martín, Domingos Silva, and Inês Filipa Sequeira Afonso. "Perfil de funcionamento do SAD, Serviço de Apoio Domiciliário - caso de Braga, Portugal." Revista Kairós : Gerontologia 22, no. 3 (2019): 9–24. http://dx.doi.org/10.23925/2176-901x.2019v22i3p9-24.

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RESUMO: O SAD português carateriza-se por um perfil tradicional. Reúne como principais caraterísticas funcionar de segunda a sexta-feira, com uma intensidade considerada baixa, com a prestação de cuidados voltada para as AVD´S, Atividades de vida diária dos idosos. Objetivos deste estudo: (i) identificar a oferta da estrutura de cuidados existentes, prestada pelo SAD, nas Instituições Particulares de Solidariedade Social (IPSS) especificamente do distrito de Braga (Portugal); e (ii) analisar seu perfil de funcionamento, com base nos comportamentos de gestão e na existência ou não dos planos de

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Martinez-Ruiz, Ricardo, Pedro Montero-Huerta, Jonathan Hromi, and C. Alvin Head. "Inhaled Nitric Oxide Improves Survival Rates during Hypoxia in a Sickle Cell (SAD) Mouse Model." Anesthesiology 94, no. 6 (2001): 1113–18. http://dx.doi.org/10.1097/00000542-200106000-00028.

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Background The hallmark of sickle cell disease (SCD) is erythrocyte sickling during deoxygenation of the abnormal hemoglobin S (HbS). When HbS is deoxygenated, it aggregates into polymers, resulting in distortion of the erythrocyte structure, producing microvascular thrombosis and ischemia. The transgenic SAD mouse produces three types of human hemoglobin: S, Antilles, and D-Punjab (HbSAD) and provides an animal model for SCD. We studied the effects of nitric oxide (NO) breathing at various doses and time regimens in the presence of severe hypoxia (6% oxygen) using the SAD mouse model. Methods

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Kontis, Dimitrios, Eirini Theochari, Alexandros Giannoulis, Fedra Louki, and Eleftheria Tsaltas. "T92. POSSIBLE COMBINATIONS OF DSM-IV AND DSM-5 CRITERIA IN SCHIZOPHRENIA AND SCHIZOAFFECTIVE DISORDER VERSUS MAJOR DEPRESSIVE AND MANIC EPISODES." Schizophrenia Bulletin 46, Supplement_1 (2020): S266—S267. http://dx.doi.org/10.1093/schbul/sbaa029.652.

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Abstract Background Psychiatric disorders diagnoses are based on the satisfaction of specific symptoms criteria. Although this categorical method of classification, which is based on the identification of clinical syndromes, has proven useful in terms of treatment, its validity has been criticized. The possible symptoms combinations for major psychotic and mood disorder diagnoses could be calculated using combinatorial mathematics and the results could provide indices of diagnostic heterogeneity. Methods Our calculations were conducted using the binomial coefficient. In mathematics, this coeff

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Pradeep, Meenakshi Sumadevi, Niteen Khanderao Nandanwankar, Priya Vishwanath Lahane, Nazima Yusuf Memon, Shridhar Devidas Yennawar, and Ramesh Govindrao Pathak. "A Randomised comparison and evaluation of I-gel, Supreme laryngeal mask airway and Ambu Auragain in Laparoscopic surgeries under general anaesthesia with controlled ventilation." Asian Journal of Medical Sciences 12, no. 4 (2021): 68–75. http://dx.doi.org/10.3126/ajms.v12i4.32931.

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Background: Supraglottic airway devices (SAD) are becoming increasingly popular for use in patients undergoing laparoscopic surgeries. In this prospective randomised study, we compared three supraglottic airway devices namely, I-gel, Supreme LMA and Ambu Auragain. Aims and Objectives: The study was undertaken to compare three supraglottic airway devices I-gel, Supreme LMA and Ambu Auragain in laparoscopic surgeries under general anaesthesia with controlled ventilation. Materials and Methods: This was a randomized comparative study in which 90 patients undergoing laparoscopic surger

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Wirz-Justice, A., K. Kräuchi, D. P. Brunner, et al. "Circadian rhythms and sleep regulation in seasonal affective disorder." Acta Neuropsychiatrica 7, no. 2 (1995): 41–43. http://dx.doi.org/10.1017/s0924270800037522.

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Seasonal affective disorder (SAD) is characterised by recurrent episodes in autumn and winter of depression, hypersomnia, augmented appetite with carbohydrate craving, and weight gain, and can be successfully treated with bright light. Circadian rhythm hypotheses (summarized in) have stimulated research into the pathophysiology of SAD, postulating that:1.The illness is a consequence of delayed phase position,2.It is correlated with diminished circadian amplitude, or3.It results from changes in the nocturnal duration between dusk and dawn e.g. of low core body temperature or melatonin secretion

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Pivovarov, E., and A. Skrydlov. "“Historical truth is a very sad thing”: Alexander von Humboldt’s correspondence with S. S. Uvarov." Voprosy istorii estestvoznaniia i tekhniki 40, no. 2 (2019): 346–66. http://dx.doi.org/10.31857/s020596060004987-7.

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Stránský, Jan, Tomáš Kovaľ, Lars Østergaard, et al. "Optimization in S-SAD phasing - difference between solved and unsolved structure." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C613. http://dx.doi.org/10.1107/s2053273314093863.

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Development of X-ray diffraction technologies have made de novo phasing of protein structures by single-wavelength anomalous dispersion by sulphur (S-SAD) more common. As anomalous differences in the sulphur atomic factors are in the order of errors of measurement, careful intensity reading and data processing are crucial. S-SAD was used for de novo phasing of a small 12 kDa protein with 4 sulphur atoms per molecule at 2.3 Å, where the data did not enable a straightforward structure solution. Data processing was performed using XDS [1] and scaling using XSCALE. The sulphur substructure was det

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Kasper, S., S. Rogers, A. Yancey, P. Schulz, R. Skwerer, and N. Rosenthal. "Phototherapy in Subsyndromal Seasonal Affective Disorder (S-SAD) and "Diagnosed" Controls." Pharmacopsychiatry 21, no. 06 (1988): 428–29. http://dx.doi.org/10.1055/s-2007-1017038.

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Budra, Paul. "Writing the Tragic Self: Richard II's Sad Stories." Renaissance and Reformation 30, no. 4 (2009): 5–15. http://dx.doi.org/10.33137/rr.v30i4.11518.

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When Shakespeare has Richard II call for the telling of "sad stories" he is not merely alluding to a tradition of medieval de casibus tragedy, but rather engaging with a well-known vision of historical teleology, popularized in Shakespeare's time by narrative historical tragedies. Shakespeare's audience, largely ignorant of the basic facts of English history, were familiar with this tragic form of history. Richard is a "self-authored subject" who finally brings his represented self into continuity with the de casibus vision.

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Tkalčević, Anja, Iva Matić, and Josipa Šegota. "Trgovinski rat između Sjedinjenih Američkih Država i Kine." Obnovljeni život 76, no. 3 (2021): 385–401. http://dx.doi.org/10.31337/oz.76.3.7.

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Rad donosi pregled nedavnih protekcionističkih mjera Sjedinjenih Američkih Država (SAD) prema Kini te daje uvid u dvogodišnji trgovinski rat između te dvije države. Analiziraju se postupci i posljedice na svjetsko gospodarstvo. Osim direktnih posljedica na Kinu i SAD, promatra se i neizravan utjecaj na druge zemlje. Promatra se svjetski trend nametanja trgovinskih mjera, njihove prednosti i nedostatci te etičke nedoumice povezane s međunarodnom trgovinskom razmjenom.

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Pjrek, E., P. Baldinger-Melich, M. Spies, K. Papageorgiou, S. Kasper, and D. Winkler. "Epidemiology and socioeconomic impact of seasonal affective disorder in Austria." European Psychiatry 32 (February 2016): 28–33. http://dx.doi.org/10.1016/j.eurpsy.2015.11.001.

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AbstractBackgroundSeasonal affective disorder (SAD) is a subtype of recurrent depressive or bipolar disorder that is characterized by regular onset and remission of affective episodes at the same time of the year. The aim of the present study was to provide epidemiological data and data on the socioeconomic impact of SAD in the general population of Austria.MethodsWe conducted a computer-assisted telephone interview in 910 randomly selected subjects (577 females and 333 males) using the Seasonal Health Questionnaire (SHQ), the Seasonal Pattern Assessment Questionnaire (SPAQ), and the Sheehan D

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Miki, M., K. Miki, G. Hajduczok, D. Curran-Everett, and J. A. Krasney. "Control of arterial pressure in conscious, sinoaortic-denervated sheep in normoxia and hypoxia." American Journal of Physiology-Heart and Circulatory Physiology 253, no. 6 (1987): H1409—H1417. http://dx.doi.org/10.1152/ajpheart.1987.253.6.h1409.

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The contribution of the sinoaortic reflexes to the control of both the mean level and variability of arterial pressure (Pa) and heart rate (HR) was studied in five adult ewes after chronic section of the carotid sinus and aortic depressor nerves (SAD). SAD group responses were compared with a sham-operated group (n = 6). Pa was 15% lower in the SAD group due to a reduction of total peripheral resistance. The standard deviations and coefficients of variation for both Pa and HR obtained by continuous 16-h monitoring (10-s intervals) in the SAD sheep were not significantly different from those of

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Kharchenko, T. A., A. S. Ivanova, O. K. Melekhovets, V. F. Orlovskyi, and Iu V. Melekhovets. "PATHOGENETIC APPROACH IN TREATMENT OF DIABETIC AND VENOUS TROPHIC ULCERS USING PLASMATHERAPY AND LASER THERAPY." Eastern Ukrainian Medical Journal 8, no. 4 (2020): 458–65. http://dx.doi.org/10.21272/eumj.2020;8(4):458-465.

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In Ukraine more than 13,000 lower limb amputations are performed per year, of which about 8,000 are due to vascular lesions, and more than 3,000 are associated with diabetes mellitus (DM). The effectiveness of photodynamic therapy (PDT) in group 1 was assessed by the VCSS-1 and VCSS-2 scales. At baseline, the total score of clinical severity of CVI was 20.9 points, and two weeks later – 15.71 points, which shows an improvement by 24.83% (p≤0.05). The effectiveness of PDT in group 2 was assessed by the S(AD) SAD-1 scales at baseline and S(AD) SAD-2 at 2 weeks. The overall score on the scale S(A

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Markušić, Bernard. "Primjena vanjskog ugovaranja u resoru obrane." Hrvatska i komparativna javna uprava 17, no. 3 (2017): 437–64. http://dx.doi.org/10.31297/hkju.17.3.5.

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Primjena vanjskog ugovaranja (outsourcinga) u resoru obrane aktualan je trend u vođenje državne obrambene politike i relativno nov fenomen u javnom upravljanju. U radu se analiziraju ekonomski i pravni aspekti vanjskog ugovaranja u resoru obrane i pokušava se odgovoriti na pitanja stvarne razine ekonomičnosti i efikasnosti takvog pristupa s jedne te pravne opravdanosti i mogućih implikacija za standarde demokracije s druge strane. Analiza počinje s općim pojmovnim određenjem vanjskog ugovaranja na skali javnoprivatnih partnerstava. Istražuje se praksa vanjskog ugovaranja primarno na primjeru S

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Mehr, Alexander, Fabian Henneberg, Ashwin Chari, Dirk Görlich, and Trevor Huyton. "The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography." Acta Crystallographica Section D Structural Biology 76, no. 12 (2020): 1222–32. http://dx.doi.org/10.1107/s2059798320013741.

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The growth of diffraction-quality crystals and experimental phasing remain two of the main bottlenecks in protein crystallography. Here, the high-affinity copper(II)-binding tripeptide GHK was fused to the N-terminus of a GFP variant and an MBP-FG peptide fusion. The GHK tag promoted crystallization, with various residues (His, Asp, His/Pro) from symmetry molecules completing the copper(II) square-pyramidal coordination sphere. Rapid structure determination by copper SAD phasing could be achieved, even at a very low Bijvoet ratio or after significant radiation damage. When collecting highly re

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Rastad, Cecilia, Jan Ulfberg, and Per Lindberg. "Improvement in Fatigue, Sleepiness, and Health-Related Quality of Life with Bright Light Treatment in Persons with Seasonal Affective Disorder and Subsyndromal SAD." Depression Research and Treatment 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/543906.

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Objective. To investigate the effects of bright light treatment for secondary outcome measures and to explore and validate empirically derived subgroups and treatment effects in subgroups.Methods. A descriptive design. A sample of forty-nine persons (mean age of 45.8) with clinically assessed seasonal affective disorder (SAD) or subsyndromal SAD (S-SAD) participated in a two-group clinical trial evaluating the effects of treatment with bright light therapy. A person-oriented cluster analysis was applied to study treatment effects in subgroups.Results. For the merged group, sleepiness (Epworth

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Sakamoto, Kazuo, Kazuya Hosokawa, Keita Saku, et al. "Baroreflex failure increases the risk of pulmonary edema in conscious rats with normal left ventricular function." American Journal of Physiology-Heart and Circulatory Physiology 310, no. 2 (2016): H199—H205. http://dx.doi.org/10.1152/ajpheart.00610.2015.

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In heart failure with preserved ejection fraction (HFpEF), the complex pathogenesis hinders development of effective therapies. Since HFpEF and arteriosclerosis share common risk factors, it is conceivable that stiffened arterial wall in HFpEF impairs baroreflex function. Previous investigations have indicated that the baroreflex regulates intravascular stressed volume and arterial resistance in addition to cardiac contractility and heart rate. We hypothesized that baroreflex dysfunction impairs regulation of left atrial pressure (LAP) and increases the risk of pulmonary edema in freely moving

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Nie, Jia, Chao Sun, Zhijie Chang, Nicolas Musi та Yuguang Shi. "SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells". Endocrinology 159, № 8 (2018): 3036–47. http://dx.doi.org/10.1210/en.2017-03243.

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Abstract Rho GDP-dissociation inhibitor (GDIα) inhibits glucose-stimulated insulin secretion (GSIS) in part by locking Rho GTPases in an inactive GDP-bound form. The onset of GSIS causes phosphorylation of GDIα at Ser174, a critical inhibitory site for GDIα, leading to the release of Rho GTPases and their subsequent activation. However, the kinase regulator(s) that catalyzes the phosphorylation of GDIα in islet β cells remains elusive. We propose that SAD-A, a member of AMP-activated protein kinase–related kinases that promotes GSIS as an effector kinase for incretin signaling, interacts with

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Dhulipala, Vamsidhara C., Wade V. Welshons, and Chada S. Reddy. "Cell cycle proteins in normal and chemically induced abnormal secondary palate development: a review." Human & Experimental Toxicology 25, no. 11 (2006): 675–82. http://dx.doi.org/10.1177/0960327106070848.

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Cell cycle progression and thus proper cell number is essential for normal development of organs and organisms. Craniofacial tissues including the secondary palate are vulnerable to disruption of cell cycle progression and proliferation by many chemicals including mycotoxin, secalonic acid D (SAD), glucocorticoids, retinoic acid and 2,3,7,8-tetrachlorodibenzodioxin. Induction of cleft palate (CP) by SAD in mice occurs from a reduction in the size of developing palatal shelves. This is associated with an inhibition of proliferation of murine and human embryonic palatal mesenchymal (MEPM and HEP

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Sun, Xiaomei, Yuxin Ye, Naofumi Sakurai, et al. "Crystallographic analysis of Eisenia hydrolysis-enhancing protein using a long wavelength for native-SAD phasing." Acta Crystallographica Section F Structural Biology Communications 76, no. 1 (2020): 20–24. http://dx.doi.org/10.1107/s2053230x19016716.

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Eisenia hydrolysis-enhancing protein (EHEP), which is a novel protein that has been identified in Aplysia kurodai, protects β-glucosidases from phlorotannin inhibition to facilitate the production of glucose from the laminarin abundant in brown algae. Hence, EHEP has attracted attention for its potential applications in producing biofuel from brown algae. In this study, EHEP was purified from the natural digestive fluid of A. kurodai and was crystallized using the sitting-drop vapor-diffusion method. Native and SAD (single-wavelength anomalous diffraction) data sets were successfully collected

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Barbiere, J. Michael, Ana Vidal, and Debra A. Zellner. "The Color of Music: Correspondence through Emotion." Empirical Studies of the Arts 25, no. 2 (2007): 193–208. http://dx.doi.org/10.2190/a704-5647-5245-r47p.

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College students listened to four song clips. Following each clip, the students indicated which color(s) corresponded to each of the four songs by distributing five points among eleven basic color names. Each song had previously been identified as either a “happy” or “sad” song. Each participant listened to two “happy” and two “sad” songs in random order. There was more agreement in color choice for the songs eliciting the same emotions than for songs eliciting different emotions. Brighter colors such as yellow, red, green, and blue were usually assigned to the happy songs and gray was usually

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Gorgel, Manuela, Jakob Ulstrup, Andreas Bøggild, et al. "Sulfur-SAD phasing and UV-RIP analysis on a single Cysteine bridge protein." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C602. http://dx.doi.org/10.1107/s2053273314093978.

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The advantage of using the anomalous signal of sulfur for phase determination is that only a single, well-diffracting crystal is needed and that a native structure will be obtained. Using long-wavelength S-SAD to a resolution of 1.9 Å we have determined the novel structure of an 89 residue protein with only 2 Cysteines fixed in a disulfide bridge. To the best of our knowledge, the Bijvoet ratio in our example is one of the smallest for which a successful structure solution by S-SAD has been reported. Data were collected on 3 different volumes of a single crystal at beamline 14.1. at BESSY II,

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Akey, David, William Brown, Jamie Konwerski, Craig Ogata, Richard Kuhn, and Janet Smith. "Adventures in Phasing: Flavivirus NS1 solved by low resolution native S-SAD." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C603. http://dx.doi.org/10.1107/s2053273314093966.

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We used native sulfur-SAD phasing to determine a novel structure of significant health importance, the flaviviruses non-structural protein 1 (NS1). Flaviviruses cause many diseases including dengue and West Nile fever. NS1 functions in both genome replication and immune system evasion. Full length, glycosylated NS1 was expressed in insect cells and crystallized. Due to difficulties with protein expression SeMet phasing was not practical, and we embarked on an effort to use sulfur-SAD phasing. To optimize the probability of observing the estimated 1.5% S-anomalous signal, we used inverse beam p

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Strenja, Rajko, and Marko Lukavac. "Priroda vanjskotrgovinskih odnosa SAD-a i EU-a s osvrtom na TTIP." Oeconomica Jadertina 8, no. 1 (2018): 30–41. http://dx.doi.org/10.15291/oec.2730.

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The US and European Union interdependence at the economic, political and security level historically represented the source of co-operation, but also tensions between two globally important economies. The strong economic, political and security ties between the United States and the EU enabled these economies to gain global supremacy, because of the links between the most powerful according to the criteria of economics and education. With the objective of keeping global supremacy, the US and the EU have strived to agree on contemporary high-standard bilateral trade agreement, socalled TTIP. Th

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Tryhubová, Pavla. "Evropská směrnice INSPIRE." Geoinformatics FCE CTU 1 (December 17, 2006): 176–83. http://dx.doi.org/10.14311/gi.1.20.

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Článek byl vytvořen na základě informací ze semináře a workshopu organizovaného sdružením Nemoforum spolu se Společným výzkumným centrem Evropské komise (EC Joint Research Centre - Ispra, Itálie) a CENIA, českou agenturou pro životní prostředí. Tématem semináře a workshopu byla Geoinformační infrastruktura ČR a INSPIRE.Česká republika vstoupila do Evropské unie (EU) spolu s dalšími devíti státy 1. května 2004. Změny na trhu s geodaty uvnitř Evropské unie se dotýkají i České republiky. Hlavním ohniskem těchto změn je iniciativa INSPIRE. INSPIRE by se měla stát evropskou směrnicí v roce 2007. IN

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Kim, K. N., D. L. Wescott, P. L. Franzen, B. P. Hasler, and K. A. Roecklein. "1092 Attention-deficit/hyperactivity Disorder Symptoms And Sleep Characteristics Within A Seasonal Affective Disorder Spectrum." Sleep 43, Supplement_1 (2020): A415—A416. http://dx.doi.org/10.1093/sleep/zsaa056.1087.

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Abstract Introduction Seasonal affective disorder (SAD) increases risk for attention-deficit/hyperactivity disorder (ADHD), although the mechanism linking SAD and ADHD is unknown. Prior research has identified insomnia and delayed sleep phase in both ADHD and SAD. We hypothesized that sleep duration and timing in SAD would be associated with the severity of ADHD symptoms. Methods Adults with SAD (n = 45) and subsyndromal SAD (S-SAD; n = 18) aged 19-66 years from Pittsburgh, PA., were assessed for ADHD symptoms, self-report sleep quality, depression severity, and daytime sleepiness in the Winte

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Brito, Fabiana Da Silva. "A influência da avaliação de desempenho para o desenvolvimento profissional dos colaboradores: um estudo de multicasos na Amazônia." Revista de Administração de Roraima - RARR 1, no. 1 (2011): 67. http://dx.doi.org/10.18227/rarr.v1i1.587.

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A avaliação de desempenho é considerada como um esforço para identificar as competências e habilidades do trabalhador ou de uma equipe de trabalho na consecução dos objetivos organizacionais. O objetivo desse estudo foi descobrir de que maneira a avaliação de desempenho influencia o desenvolvimento profissional dos colaboradores, como também suas influências no processo decisório dos gestores. Realizou-se, assim, um estudo de multicasos no Sistema “S” de Boa Vista-RR, de carater qualiquantitativo em seis instituições, composta de entrevistas semi-estruturadas com os gestores e questionário com

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Patel, K. P., J. D. Peuler, D. A. Morgan, B. J. Pardini, D. D. Lund, and P. G. Schmid. "Central noradrenergic activity in intact and sinoaortic denervated Dahl rats." Canadian Journal of Physiology and Pharmacology 67, no. 5 (1989): 450–55. http://dx.doi.org/10.1139/y89-072.

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Lesions in forebrain areas richly innervated by noradrenergic terminals and involved in cardiovascular function reduce or prevent hypertension in the Dahl salt-sensitive (S) rats fed a high (H) salt diet. This led us to examine two questions. (1) Is the noradrenergic activity altered in discrete forebrain and brainstem areas of SH rats? (2) Are these changes in noradrenergic activity eliminated by sinoaortic denervation (SAD)? Studies were done in 10-week-old female SH and Dahl salt-resistant (RH) rats. Half of the rats in each group had SAD surgery 1 week prior to study. An index of norepinep

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