Relevant bibliographies by topics / Saccular aneurysm

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Saccular aneurysm'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Saccular aneurysm"

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Kim, Choegon, Haruhiko Kikuchi, Nobuo Hashimoto, and Fumitada Hazama. "Angiographic Study of Induced Cerebral Aneurysms in Primates." Neurosurgery 27, no. 5 (1990): 715–20. http://dx.doi.org/10.1227/00006123-199011000-00008.

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Abstract Five cynomolgus monkeys treated with unilateral carotid ligation, renal hypertension, and β-aminopropionitrile feeding were studied repeatedly by cerebral angiography to clarify the growth process of saccular cerebral aneurysms. Repeated angiography demonstrated saccular cerebral aneurysms in three of five monkeys; two aneurysms were found 15 months and a third 12 months after the operation. At autopsy, one saccular aneurysm was found to be bilocular in shape, and the others were unilocular. Fusiform aneurysms were also observed in four monkeys. Microscopic studies revealed the walls
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Okamoto, T., S. Miyachi, M. Negoro, et al. "Gene Transfer for Experimental Saccular Aneurysms." Interventional Neuroradiology 7, no. 1_suppl (2001): 131–35. http://dx.doi.org/10.1177/15910199010070s119.

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Reinforcing an aneurysmal wall is one possible way to prevent from aneurysm rupture. We preliminarily tried focal gene transfer against the wall of experimental aneurysms to aim the transgene remodeling of aneurysmal wall. Two experimental saccular aneurysms were created on canine common carotid artery with an artificial dissecting method, which resemble clinical aneurysms. Adenovirus vector (AxCALacZ, 108 pfu) was slowly injected into the aneurysm cavity for over 30 minutes under the condition of in-traaneurysmal flow arrest using balloon-assisted neck-plasty technique. The arteries and aneur
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Marcellana, Gwen R., Marie Antoinette Lacson, Precious Emary E. Samonte, Ferdinand V. Alzate, Marvin D. Martinez, and Fabio Enrique B. Posas. "Hybrid Thoracic Endovascular Repair of a Large, Saccular Aortic Arch Aneurysm with Coil Embolization of the Left Subclavian Artery in a 31 Year Old Filipino Female with Takayasu Arteritis and Multiple Intracranial Aneurysms: A First in the Philippines." Philippine Journal of Cardiology 52, no. 2 (2024): 50–54. http://dx.doi.org/10.69944/pjc.9fe715c7c9.

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BACKGROUND: Takayasu Arteritis (TA) is a rare, primary large-vessel vasculitis frequently leading to stenosis and less commonly, aneurysm formation. Saccular aneurysms of the aortic arch in patients with TA are fatal, have rarely been reported and represent a significant technical challenge due to the difficult anatomical location and need for protection of the cerebral circulation. Concomitant intracerebral aneurysms in patients with TA are extremely uncommon and have mostly been documented in very few case reports in literature. CASE DISCUSSION: We present a case of a 31 year-old Filipino fe
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Li, Da, Yunxia Jiang, Chengjun Zhuge, and An Wu. "Treatment of aneurysmal artery with PED: A case report." Medicine 102, no. 48 (2023): e36377. http://dx.doi.org/10.1097/md.0000000000036377.

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Rationale: Pipeline embolization devices are a new treatment for intracranial aneurysms, especially irregular, giant aneurysms. Patient concerns: A 48-year-old female patient presented with a headache in the frontal part for 3 weeks. Diagnoses: Cerebral computed tomographic angiography and magnetic resonance angiography showed a saccular aneurysm in the right internal carotid artery that wrapped the parent artery. Digital subtraction angiography provided images with 1 large saccular internal carotid aneurysm. Interventions: The patient was treated by flow diverter stent and coil embolization a
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Hamada, Fumihiro, Hitoshi Fukuda, Yuma Hosokawa, et al. "Non-Saccular Aneurysm Shape as a Poor Prognostic Factor in Younger Patients with Spontaneous Subarachnoid Hemorrhage." Journal of Clinical Medicine 14, no. 12 (2025): 4289. https://doi.org/10.3390/jcm14124289.

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Background/Objectives: Non-saccular aneurysms are a rare subtype of intracranial aneurysms with complex morphologies. Although treatment strategies for ruptured non-saccular and saccular aneurysms differ significantly, large-scale comparisons of the outcomes between the two types remain limited. We aimed to compare the clinical characteristics, procedure-related complications, and functional outcomes between patients with subarachnoid hemorrhage (SAH) caused by non-saccular or saccular aneurysms. Methods: We retrospectively analyzed 1176 consecutive patients with aneurysmal SAH from a populati
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Byndiu, A. V., M. Yu Orlov, M. V. Yelieinyk, and S. O. Lytvak. "Prevention of complication in cerebral aneurysm microsurgery, associated with their non-radical clipping." Endovascular Neuroradiology 33, no. 3 (2020): 66–77. http://dx.doi.org/10.26683/2304-9359-2020-3(33)-66-77.

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Objective ‒ to analyze the effectiveness of intraoperative contact Doppler, repositioning the clip on the aneurysm and pilot clipping of the cervical aneurysm as the main methods of prevention of inadequate clipping of the cervical aneurysm in patients with intraoperative rupture of aneurysms. Materials and methods. Due to the use of intraoperative contact ultrasound Doppler control it was possible to avoid inadequate clipping of cerebral aneurysms in 16 cases, of which in 12 (75.00 %) cases ‒ incomplete clipping of cerebral aneurysms, in 3 (18.75 %) cases ‒ compression of the aneurysm’s arter
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Pinto, J. R., J. M. Godoy, C. R. Telles, C. S. Faria, M. V. S. Avelar, and D. H. Nicaretta. "Intracranial saccular aneurysm." Arquivos de Neuro-Psiquiatria 50, no. 4 (1992): 523–27. http://dx.doi.org/10.1590/s0004-282x1992000400018.

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The authors report the cases of three patients from the same family, all with intracranial saccular aneurysm (left carotid artery, anterior communicating artery, and middle cerebral artery). All three patients were operated on with good recovery and no complications. The authors call attention for some etipathogenic aspects of familial saccular aneurysms.
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Spetzler, Robert F., Joseph M. Zabramski, Cameron G. McDougall, et al. "Analysis of saccular aneurysms in the Barrow Ruptured Aneurysm Trial." Journal of Neurosurgery 128, no. 1 (2018): 120–25. http://dx.doi.org/10.3171/2016.9.jns161301.

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OBJECTIVEThe Barrow Ruptured Aneurysm Trial (BRAT) is a prospective, randomized trial in which treatment with clipping was compared to treatment with coil embolization. Patients were randomized to treatment on presentation with any nontraumatic subarachnoid hemorrhage (SAH). Because all other randomized trials comparing these 2 types of treatments have been limited to saccular aneurysms, the authors analyzed the current BRAT data for this subgroup of lesions.METHODSThe primary BRAT analysis included all sources of SAH: nonaneurysmal lesions; saccular, blister, fusiform, and dissecting aneurysm
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OLIVEIRA, JAHIR RICHARD DE, MAURÍCIO DE AMORIM AQUINO, SVETLANA BARROS, GUILHERME BENJAMIN BRANDÃO PITTA, and ADAMASTOR HUMBERTO PEREIRA. "Alterations of blood flow pattern after triple stent endovascular treatment of saccular abdominal aortic aneurysm: a porcine model." Revista do Colégio Brasileiro de Cirurgiões 43, no. 3 (2016): 154–59. http://dx.doi.org/10.1590/0100-69912016003004.

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ABSTRACT Objective: to determine the blood flow pattern changes after endovascular treatment of saccular abdominal aortic aneurysm with triple stent. Methods: we conducted a hemodynamic study of seven Landrace and Large White pigs with saccular aneurysms of the infrarenal abdominal aorta artificially produced according to the technique described. The animals were subjected to triple stenting for endovascular aneurysm. We evaluated the pattern of blood flow by duplex scan before and after stent implantation. We used the non-paired Mann-Whitney test for statistical analysis. Results: there was a
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Ohki, Masafumi. "Thoracic Saccular Aortic Aneurysm Presenting with Recurrent Laryngeal Nerve Palsy prior to Aneurysm Rupture: A Prodrome of Thoracic Aneurysm Rupture?" Case Reports in Otolaryngology 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/367873.

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Left recurrent laryngeal nerve palsy rarely results from cardiac disease. We present 2 cases of left recurrent laryngeal nerve palsy caused by thoracic saccular aortic aneurysms. One patient suffered an aortic aneurysm rupture one month after the advent of hoarseness, necessitating emergency surgery with aortic arch replacement. The other patient underwent elective aortic arch replacement surgery. Both saccular aortic aneurysms protruded downward in the aortopulmonary window to compress the recurrent laryngeal nerves. This is only the 5th case report of the rare occurrence of acute recurrent l
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Dissertations / Theses on the topic "Saccular aneurysm"

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Farley, Cory Wayne. "Parameterization of the size and shape of intracranial saccular aneurysms using Legendre polynomials." Thesis, Texas A&M University, 2004. http://hdl.handle.net/1969.1/1432.

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Currently, size is used as the predetermining factor to judge whether a saccular aneurysm is likely to rupture. Recent studies of the nonlinear mechanics of saccular aneurysms suggest that it is unlikely that they enlarge or rupture via material (limit point) or dynamic (resonance) instabilities. Rather, there is a growing body of evidence from both vascular biology and finite element analyses that implicate mechanosensitive growth and remodeling processes. There is, therefore, an even greater need to quantify regional multiaxial wall stresses, which because of the membrane-like behavior of an
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Shimizu, Kampei. "Hemodynamic Force as a Potential Regulator of Inflammation-Mediated Focal Growth of Saccular Aneurysms in a Rat Model." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264652.

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京都大学<br>新制・課程博士<br>博士(医学)<br>甲第23371号<br>医博第4740号<br>新制||医||1051(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 髙橋 良輔, 教授 安達 泰治, 教授 YOUSSEFIAN Shohab<br>学位規則第4条第1項該当<br>Doctor of Medical Science<br>Kyoto University<br>DFAM
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Lipenský, Zdeněk. "Vliv okolní tkáně na napjatost výdutě mozkových tepen." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230311.

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This thesis is focused on stress in brain aneurysms. It consists of three parts. First part is aimed for gaining information about the topic from scientific resources. Next part consists of analyses of geometry of cerebral aneurysms on the computed wall stress. Analyses are performed on four basic geometrical models and results are being discussed. The risky areas in each investigated shape have been identified as well as the comparisons of stress between those shapes have been performed and the most dangerous shape among investigated shapes has been determined. Third part investigates the inf
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Perini, Sílvio César. "Modelo suino de aneurisma de aorta abdominal com bolsa de pericárdio bovino." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/15224.

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Introdução: A correção do aneurisma pela técnica endovascular ganha mais espaço com o aprimoramento do material utilizado, buscando-se um sistema ideal. Os estudos com esses dispositivos necessitam de modelos experimentais que devem apresentar características anatômicas e fisiopatológicas similares aos aneurismas em humanos. Apresentamos um novo modelo com bolsa de pericárdio bovino em suínos, com abordagem cirúrgica por via retroperitonial. Materiais e métodos: Estudo prospectivo, de coorte, avaliado pelo comitê de bioética, utilizando 11 suínos de raça Large White e do sexo feminino, com ida
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Cantón, María De Gádor. "Hemodynamics of intracranial saccular aneurysms /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3153695.

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MacDonald, Donia J. "Wall characteristics of saccular aneurysms from polarized light microscopy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0006/MQ42172.pdf.

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Books on the topic "Saccular aneurysm"

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Skirgaudas, Mark. Expression of angiogenesis factors and selected vascular wall matrix proteins in intracranial saccular aneurysms. s.n.], 1997.

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Mehta, Nikhil, and Bulent Arslan. Techniques for Treating Visceral Aneurysms and High-Flow Arteriovenous Malformations of the Renal and Visceral Vasculature. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0028.

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Techniques for treating visceral aneurysms are based on location and anatomic region and also on whether an aneurysm is a true aneurysm or a pseudoaneurysm. Visceral artery aneurysms typically require treatment if they are greater than 2 cm. Aneurysms that are favorable for endovascular therapy include saccular aneurysms preferably with a narrow neck and/or aneurysms that have good collateral blood flow to the target organ. Endovascular techniques for treating arteriovenous malformations (AVMs) are multifaceted and require appropriate identification of the AVM using multiple imaging modalities
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Surgical techniques for saccular and giant intracranial aneurysms. Williams & Wilkins, 1990.

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Experimental and Clinical Treatment of Subarachnoid Hemorrhage after Rupture of Saccular Intracranial Aneurysms. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03943-155-7.

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Experimental and Clinical Treatment of Subarachnoid Hemorrhage after Rupture of Saccular Intracranial Aneurysms. Mdpi AG, 2020.

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Michel, Jean-Baptiste. Biology of vascular wall dilation and rupture. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755777.003.0016.

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Arterial pathologies, important causes of death and morbidity in humans, are closely related to modifications in the circulatory system during evolution. With increasing intraluminal pressure and arterial bifurcation density, the arterial wall becomes the target of interactions with blood components and outward convection of plasma solutes and particles, including plasma zymogens and leukocyte proteases. Abdominal aortic aneurysms of atherothrombotic origin are characterized by the presence of an intraluminal thrombus (ILT), a major source of proteases, including plasmin, MMP-9, and elastase.
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Book chapters on the topic "Saccular aneurysm"

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Pronin, Igor, and Valery Kornienko. "Saccular Arterial Aneurysm." In CT and MRI of Skull Base Lesions. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-65957-2_19.

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Cohen, José E., Hosni Abu Al-Hasan, and Samuel Moscovici. "Middle Cerebral Artery Bifurcation Aneurysm: Saccular Aneurysm of the Middle Cerebral Artery Bifurcation Treated with a Flow Diverter Stent." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77827-3_95.

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Cohen, José E., Hosni Abu Al-Hasan, and Samuel Moscovici. "Middle Cerebral Artery Bifurcation Aneurysm: Saccular Aneurysm of the Middle Cerebral Artery Bifurcation Treated with a Flow Diverter Stent." In The Aneurysm Casebook. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-70267-4_95-1.

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Cohen, José E., Gustavo Rajz, Samuel Moscovici, and Hans Henkes. "Pericallosal Artery Aneurysm: Acutely Ruptured Prenidal Pericallosal Artery Aneurysms; Coil Occlusion for a Saccular Aneurysm and Flow Diverter Stent Implant for a Dissecting Aneurysm." In The Aneurysm Casebook. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-70267-4_190-1.

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AlMatter, Muhammad, Marta Aguilar Pérez, Oliver Ganslandt, and Hans Henkes. "Middle Cerebral Artery Aneurysm: Incidental Small Saccular MCA Aneurysm with Complex Geometry in a Patient with Ischemic Pontine Stroke – Microsurgical Clipping of the Saccular Aneurysm and Wrapping of a Blister Aneurysm on the Inferior MCA Branch; Postoperative DSA Confirmed the Complete Occlusion of the Saccular Aneurysm and Patency of Both Efferent MCA Branches; Development of a High-Grade Stenosis of the Inferior Trunk of the MCA, Possibly Induced by Muslin Gauze, and Eventually Formation of a De Novo Aneurysm." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77827-3_18.

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AlMatter, Muhammad, Marta Aguilar Pérez, Oliver Ganslandt, and Hans Henkes. "Middle Cerebral Artery Aneurysm: Incidental Small Saccular MCA Aneurysm with Complex Geometry in a Patient with Ischemic Pontine Stroke – Microsurgical Clipping of the Saccular Aneurysm and Wrapping of a Blister Aneurysm on the Inferior MCA Branch (Postoperative DSA Confirmed the Complete Occlusion of the Saccular Aneurysm and Patency of Both Efferent MCA Branches – Development of a High-Grade Stenosis of the Inferior Trunk of the MCA, Possibly Induced by Muslin Gauze, and Eventually Formation of a De Novo Aneurysm)." In The Aneurysm Casebook. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-70267-4_18-1.

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Cohen, José E., John M. Gomori, Shalom Mijovich, Moatasim Shweiki, and Gustavo Rajz. "Posterior Cerebral Artery Aneurysm: Pediatric Giant Non-saccular Posterior Cerebral Artery Aneurysm Treated with a Scaffold Stent, Double Flow Diverters, and Posterior Communicating Artery Disconnection by Coiling." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-70267-4_171-1.

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Wong, Ken, William Crinnion, Levansri Makalanda, and Pervinder Bhogal. "Middle Cerebral Artery Bifurcation Aneurysm: Acute Subarachnoid Hemorrhage Secondary to a Saccular Aneurysm Arising from the Bifurcation of the Middle Cerebral Artery – Endovascular Treatment with the Woven EndoBridge Device." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77827-3_131.

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Wong, Ken, William Crinnion, Levansri Makalanda, and Pervinder Bhogal. "Middle Cerebral Artery Bifurcation Aneurysm: Acute Subarachnoid Hemorrhage Secondary to a Saccular Aneurysm Arising from the Bifurcation of the Middle Cerebral Artery – Endovascular Treatment with the Woven EndoBridge Device." In The Aneurysm Casebook. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-70267-4_131-1.

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Lylyk, Ivan, Rene Viso, Rodrigo Muñoz, Jorge Chudyk, and Pedro Lylyk. "Internal Carotid Artery Aneurysm: Large Saccular Persistent Primitive Trigeminal Artery Aneurysm, with Mass Effect, Treated with Flow Diverter and Deconstructive Technique with Coils, Good Clinical Outcome, and Follow-Up Results." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77827-3_145.

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Conference papers on the topic "Saccular aneurysm"

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Lee, Sang Hyuk, Nahmkeon Hur, and Seongwon Kang. "An Approach on Fluid-Structure Interaction for the Prediction of Blood Flow in Aneurysms With Various Shapes." In ASME 2013 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/fedsm2013-16397.

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Recently, the rapid evolution of numerical methodologies for CFD and structural analyses has made it possible to predict the arterial hemodynamics closely related to vascular disease. In the present study, a framework for fluid-structure interaction (FSI) analysis was developed to accurately predict the arterial hemodynamics. The numerical results from the FSI analysis of the hemodynamics inside aneurysms of various shapes were compared to the results without FSI analysis. The results showed that FSI analysis needs to be performed in order to accurately predict the blood flow affected by the w
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Kroon, Martin, and Gerhard Holzapfel. "A Theoretical Model for Saccular Cerebral Aneurysm Growth: Deformation and Stress Analysis." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176857.

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Aneurysms are abnormal dilatations of arteries, and these lesions are found almost exclusively in humans. Saccular cerebral aneurysms occur most frequently in the Circle of Willis, which is a circuit of arteries supplying the brain with blood. Aneurysms of this kind appear in a few percent of the human population in the Western world. Only a few percent of these lesions do actually rupture, but once rupture occurs the consequences are severe, often with death as outcome. Once a cerebral aneurysm is detected, clinicians need to decide whether operation is required or not. These decisions are ma
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Curtis, Colin W., and Michael L. Calvisi. "Axisymmetric Model of an Intracranial Saccular Aneurysm: Theory and Computation." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-66383.

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An axisymmetric model of an intracranial saccular aneurysm is presented and analyzed. The model assumes a simplified spherical geometry for the aneurysm in order to develop insight into the mechanisms that effect wall shear stress and deformation of the membrane. A theoretical model is first developed based on Stokes’ equations for viscous flow in order to derive a stream function that describes vortical flow inside a sphere representative of flow inside a real aneurysm. This flow pattern is implemented in a finite element model of a spherical aneurysm using the software COMSOL Multiphysics. T
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Jou, Liang-Der. "Reduction of Flow Rate Into a Saccular Aneurysm After Stenting." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32583.

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Stents, wire-frame structures, are very effective devices in the treatment of vascular diseases, such as stenoses and aneurysms. One-third of patients who have stent placements develop restenosis over a six-month period, with the cause thought to be hemodynamic-related. The use of stent grafts to treat aneurysms often leads to exclusion of smaller vessels adjacent to the aneurysm from the circulation, and success of this procedure may therefore depend on the size of small vessels being occluded. An open stent is preferred to preserve the blood supply to neighboring vessels, but is considered t
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Shimogonya, Y., T. Ishikawa, Y. Imai, D. Mori, and T. Yamaguchi. "The Importance of Proliferation of the Arterial Wall in Formation of Saccular Cerebral Aneurysms." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193267.

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Cerebral aneurysms are an important cerebrovascular condition because aneurysm rupture is the most common cause of subarachnoid hemorrhage, which has a high mortality rate and a poor prognosis. Since the mechanism of cerebral aneurysm pathogenesis has not yet been understood, the preventative treatment for unruptured aneurysms is surgery only; however, the morbidity of the surgery is as high as over 10% [1]. On the other hand, the annual risk of rupture of cerebral aneurysms is not so high, reported to be 1.9% [2]. Consequently, it is difficult to judge whether a patient with an unruptured cer
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Tsai, William W., O¨mer Savas, Duncan Maitland, et al. "Experimental Study of the Vascular Dynamics of a Saccular Basilar Aneurysm." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-14662.

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A majority of patients who suffer hemorrhaging as a result of a ruptured cerebral aneurysm experience reduced quality of life, long term brain damage, or death. Improved understanding of the flow patterns in cerebral aneurysms will lead to better techniques for their detection and treatment. Experiments are conducted in a generic flow phantom to characterize the basic behavior of blood flow in basilar saccular aneurysms. The test setup models a saccular aneurysm that forms at the bifurcation of the basilar artery into the Circle of Willis. Three input flow conditions are tested: a physiologica
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Zeng, Zijing, David F. Kallmes, Yong Hong Ding, et al. "Hemodynamics of Elastase-Induced Aneurysms in Rabbit: A New High Flow Bifurcation Model." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53819.

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An intracranial aneurysm (IA) is a pathological condition of cerebral arteries characterized by local enlargements of the arterial wall, typically into a saccular shape. Rupture of the aneurysm sac can result in devastating cerebral hemorrhage. Hemodynamic factors are believed to play an important role in initiation, development and rupture of IAs [1–3]. However, the coupling between hemodynamics and aneurysm pathophysiology is complex and remains poorly understood. Patient specific diagnostics regarding risk of rupture can be substantially advanced by improving our understanding of the in-viv
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Gundert, Timothy J., and John F. LaDisa. "Evaluation of Cerebral Aneurysm Stent Performance in a Subject-Specific Computational Model." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19670.

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Rupture of cerebral aneurysms is the second leading cause of stroke in the United States [1]. Altered hemodynamics is thought to play a role in the progression and subsequent rupture of aneurysms. Blood flow into an aneurysm can be occluded by surgically clipping the aneurysm or using endovascular devices, such as stents or coils. In saccular aneurysms, coiling alone may be a sufficient method of inducing flow stagnation in the aneurysm, causing thrombosis and preventing rupture. When treating wide-necked aneurysms, stenting is often used in conjunction with coiling to prevent the migration of
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Pichamuthu, Joseph E., Alkiviadis Tsamis, Brian T. Jankowitz, and David A. Vorp. "Association of Wall Stress of Human Intracranial Saccular Aneurysm With Coil Packing Density After Coil Embolization." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80782.

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Coil embolization has become a widely accepted endovascular procedure for intracranial aneurysms, as an alternative to surgical clipping [1,2]. This procedure involves treating an aneurysm from the inside out, whereby metallic coils are placed into the aneurysm to induce thrombosis of the lumen and eliminate the risk of rupture and hemorrhage. Successful endosaccular packing mainly depends on the morphological features and size of the aneurysm, and the relationship of the aneurysm to the cerebral arteries.
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10

Baek, Hyoungsu, Mahesh V. Jayaraman, and George Em Karniadakis. "Distribution of WSS on the Internal Carotid Artery With an Aneurysm: A CFD Sensitivity Study." In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-41796.

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Abstract:
Intracranial blood flow simulations for studying brain aneurysms are based on many assumptions including the Womersley profile for the inlet boundary condition. Moreover, computational domains seem to be more or less arbitrarily chosen. Previous studies have shown that long inlet vessels lead to more realistic flow just upstream of the aneurysm. In order to guide our studies of cerebral aneurysms, using the high-order spectral/hp element method, we systematically investigated the geometric sensitivity of wall shear stress (WSS) on aneurysms; specifically, the effect of parent vessel geometry o
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