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Journal articles on the topic 'Saccule and Utricle'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

Curthoys, Ian S., Ann M. Burgess, and Leonardo Manzari. "The Evidence for Selective Loss of Otolithic Function." Seminars in Neurology 40, no. 01 (2019): 033–39. http://dx.doi.org/10.1055/s-0039-3402064.

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AbstractRecent advances in vestibular testing now permit functional testing of all peripheral vestibular sense organs (all three semicircular canals, utricle, and saccule). This makes it possible to identify patients with isolated dysfunction of the utricle or saccule, even though parallel pathways for vestibular information are ultimately integrated centrally. Selective, isolated unilateral loss of utricular function as measured by ocular vestibular-evoked myogenic potentials (VEMPs) has been observed in patients with normal semicircular canal function as measured by the video head impulse te

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2

Lozier, Nicholas R., and Joseph A. Sisneros. "Ontogeny of Inner Ear Saccular Development in the Plainfin Midshipman (Porichthys notatus)." Brain, Behavior and Evolution 95, no. 6 (2020): 330–40. http://dx.doi.org/10.1159/000516477.

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The auditory system of the plainfin midshipman fish (<i>Porichthys notatus</i>) is an important sensory system used to detect and encode biologically relevant acoustic stimuli important for survival and reproduction including social acoustic signals used for intraspecific communication. Previous work showed that hair cell (HC) density in the midshipman saccule increased seasonally with reproductive state and was concurrent with enhanced auditory saccular sensitivity in both females and type I males. Although reproductive state-dependent changes in HC density have been well characte

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3

Clarke, A. H., U. Schönfeld, and K. Helling. "Unilateral examination of utricle and saccule function." Journal of Vestibular Research 13, no. 4-6 (2003): 215–25. http://dx.doi.org/10.3233/ves-2003-134-606.

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Attention is directed towards the recently developed unilateral tests of saccular and utricular function. Together with the now widely used head-thrust test and the standard caloric test for semicircular canal function, these provide for a more comprehensive unilateral examination of labyrinth function. The efficacy of vestibular evoked myogenic potentials (VEMP) as a direct unilateral test of saccular function is currently being demonstrated in an increasing number of reports. Furthermore, the relevant neuronal pathways have been delineated in animal studies, so that all evidence points to th

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4

Hageman, Kristin N., Margaret R. Chow, Dale Roberts, et al. "Binocular 3D otolith-ocular reflexes: responses of chinchillas to prosthetic electrical stimulation targeting the utricle and saccule." Journal of Neurophysiology 123, no. 1 (2020): 259–76. http://dx.doi.org/10.1152/jn.00883.2018.

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From animal experiments by Cohen and Suzuki et al. in the 1960s to the first-in-human clinical trials now in progress, prosthetic electrical stimulation targeting semicircular canal branches of the vestibular nerve has proven effective at driving directionally appropriate vestibulo-ocular reflex eye movements, postural responses, and perception. That work was considerably facilitated by the fact that all hair cells and primary afferent neurons in each canal have the same directional sensitivity to head rotation, the three canals’ ampullary nerves are geometrically distinct from one another, an

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5

Helling, Kai, Hans Scherer, Stefan Hausmann, and Andrew H. Clarke. "Otolith mass asymmetries in the utricle and saccule of flatfish." Journal of Vestibular Research 15, no. 2 (2005): 59–64. http://dx.doi.org/10.3233/ves-2005-15201.

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The otolith mass of the saccules and utricles of plaice, Pleuronectes platessa (n = 39) and turbot, Psetta maxima (n = 21) was measured using an electronic microbalance. In the right-eyed plaice, the left utricular otoliths were found to be significantly heavier than the right (p < 0.0001), whereas no significant difference was found between left and right saccular otoliths (p < 0.751). In the left-eyed turbot, both the right utricular and saccular otoliths were found to be significantly heavier (in both cases, p < 0.0001). While the gene and regulative protein responsible for the per

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6

Pauw, Bernard K. H., Anita M. Pollak, and Ugo Fisch. "Utricle, Saccule, and Cochlear Duct in Relation to Stapedotomy." Annals of Otology, Rhinology & Laryngology 100, no. 12 (1991): 966–70. http://dx.doi.org/10.1177/000348949110001203.

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This study was performed to determine the area in which and the circumstances under which stapedotomy can be relatively safely performed. Measurements were made from central areas of the medial surface of the stapedial footplate to the utricle, the saccule, and the cochlear duct in 10 normal and 11 otosclerotic temporal bones. The mean distances to the utricle ranged from 1.9 to 2.4 mm, and those to the saccule from 1.7 to 2.1 mm. The minimal distance to the utricle was measured from the posterior (0.58 mm) and superior (0.62 mm) borders of the stapedial footplate. The minimal distances to the

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7

Papathanasiou, Eleftherios S. "Ocular vestibular evoked myogenic potentials (OVEMPs): Saccule or utricle?" Clinical Neurophysiology 123, no. 2 (2012): 216. http://dx.doi.org/10.1016/j.clinph.2011.06.013.

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8

Morsli, H., F. Tuorto, D. Choo, M. P. Postiglione, A. Simeone, and D. K. Wu. "Otx1 and Otx2 activities are required for the normal development of the mouse inner ear." Development 126, no. 11 (1999): 2335–43. http://dx.doi.org/10.1242/dev.126.11.2335.

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The Otx1 and Otx2 genes are two murine orthologues of the Orthodenticle (Otd) gene in Drosophila. In the developing mouse embryo, both Otx genes are expressed in the rostral head region and in certain sense organs such as the inner ear. Previous studies have shown that mice lacking Otx1 display abnormal patterning of the brain, whereas embryos lacking Otx2 develop without heads. In this study, we examined, at different developmental stages, the inner ears of mice lacking both Otx1 and Otx2 genes. In wild-type inner ears, Otx1, but not Otx2, was expressed in the lateral canal and ampulla, as we

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9

Liu, Huizhan, and Lidong Zhao. "Recording potentials from scala media, saccule and utricle in mice." Journal of Otology 10, no. 2 (2015): 87–91. http://dx.doi.org/10.1016/j.joto.2015.09.003.

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10

Deng, Di, Xiaoqing Qian, Binjun Chen, et al. "Canonical Wnt Signaling Pathway on Polarity Formation of Utricle Hair Cells." Neural Plasticity 2021 (May 22, 2021): 1–11. http://dx.doi.org/10.1155/2021/9950533.

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As part of the inner ear, the vestibular system is responsible for sense of balance, which consists of three semicircular canals, the utricle, and the saccule. Increasing evidence has indicated that the noncanonical Wnt/PCP signaling pathway plays a significant role in the development of the polarity of the inner ear. However, the role of canonical Wnt signaling in the polarity of the vestibule is still not completely clear. In this study, we found that canonical Wnt pathway-related genes are expressed in the early stage of development of the utricle and change dynamically. We conditionally kn

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11

Ashman, Robert B., John M. Papadimitriou, and Alma Fulurija. "Acute labyrinthitis associated with systemicCandida albicansinfection in ageing mice." Journal of Laryngology & Otology 110, no. 1 (1996): 13–18. http://dx.doi.org/10.1017/s0022215100132621.

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AbstractThe yeastCandida albicansis an important opportunistic pathogen that has been associated with disease of the inner ear. This study describes the histopathology of acute labyrinthitis caused by systemic infection with C.albicansin ageing inbred mice. Within four days after infection, yeast and hyphal forms of C.albicanswere found in the membranous labyrinth. The utricle and the adjacent parts of the ampullary regions of the semicircular canals were most severely affected, but damage was also seen in the scala media, the Scala tympani, the saccule, and the scala vestibuli. In the utricle

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12

Rogers, Loranzie S., and Joseph A. Sisneros. "Auditory evoked potentials of utricular hair cells in the plainfin midshipman, Porichthys notatus." Journal of Experimental Biology 223, no. 17 (2020): jeb226464. http://dx.doi.org/10.1242/jeb.226464.

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ABSTRACTThe plainfin midshipman, Porichthys notatus, is a soniferous marine teleost fish that generates acoustic signals for intraspecific social communication. Nocturnally active males and females rely on their auditory sense to detect and locate vocally active conspecifics during social behaviors. Previous work showed that the midshipman inner ear saccule and lagena are highly adapted to detect and encode socially relevant acoustic stimuli, but the auditory sensitivity and function of the midshipman utricle remain largely unknown. Here, we characterized the auditory evoked potentials from ha

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13

Dickman, J. David, David Huss, and Melissa Lowe. "Morphometry of otoconia in the utricle and saccule of developing Japanese quail." Hearing Research 188, no. 1-2 (2004): 89–103. http://dx.doi.org/10.1016/s0378-5955(03)00377-0.

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14

Lundy, Larry. "The Effect of CO2and KTP laser on the cat saccule and utricle." Laryngoscope 119, no. 8 (2009): 1594–605. http://dx.doi.org/10.1002/lary.20517.

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15

Jamali, Mohsen, Soroush G. Sadeghi, and Kathleen E. Cullen. "Response of Vestibular Nerve Afferents Innervating Utricle and Saccule During Passive and Active Translations." Journal of Neurophysiology 101, no. 1 (2009): 141–49. http://dx.doi.org/10.1152/jn.91066.2008.

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The distinction between sensory inputs that are a consequence of our own actions from those that result from changes in the external world is essential for perceptual stability and accurate motor control. In this study, we investigated whether linear translations are encoded similarly during active and passive translations by the otolith system. Vestibular nerve afferents innervating the saccule or utricle were recorded in alert macaques. Single unit responses were compared during passive whole body, passive head-on-body, and active head-on-body translations (vertical, fore-aft, or lateral) to

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16

Antonelli, Patrick J., G. Joseph Parell, Gary D. Becker, and Michael M. Paparella. "Temporal Bone Pathology in Scuba Diving Deaths." Otolaryngology–Head and Neck Surgery 109, no. 3 (1993): 514–21. http://dx.doi.org/10.1177/019459989310900321.

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Scuba diving has long been associated with otologic injuries; however, little is known about temporal bone pathology in diving-related deaths. We examined 18 temporal bones from 11 divers who died, primarily from complications of rapid ascent. Bleeding into the middle ear and mastoid air cells was nearly universal. Inner ear damage included hemorrhage around Reissner's membrane and the round window membrane and rupture of the utricle and saccule. Most of the observed inner ear damage was not surgically treatable. (OTOLARYNGOL HEAD NECK SURG 1993;109:514-21.)

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17

Fife, Terry D., James G. Colebatch, Kevin A. Kerber, et al. "Practice guideline: Cervical and ocular vestibular evoked myogenic potential testing." Neurology 89, no. 22 (2017): 2288–96. http://dx.doi.org/10.1212/wnl.0000000000004690.

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Objective:To systematically review the evidence and make recommendations with regard to diagnostic utility of cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP, respectively). Four questions were asked: Does cVEMP accurately identify superior canal dehiscence syndrome (SCDS)? Does oVEMP accurately identify SCDS? For suspected vestibular symptoms, does cVEMP/oVEMP accurately identify vestibular dysfunction related to the saccule/utricle? For vestibular symptoms, does cVEMP/oVEMP accurately and substantively aid diagnosis of any specific vestibular disorder besides SCDS?

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18

Wang, W., T. Van De Water, and T. Lufkin. "Inner ear and maternal reproductive defects in mice lacking the Hmx3 homeobox gene." Development 125, no. 4 (1998): 621–34. http://dx.doi.org/10.1242/dev.125.4.621.

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The Hmx homeobox gene family is of ancient origin, being present in species as diverse as Drosophila, sea urchin and mammals. The three members of the murine Hmx family, designated Hmx1, Hmx2 and Hmx3, are expressed in tissues that suggest a common functional role in sensory organ development and pregnancy. Hmx3 is one of the earliest markers for vestibular inner ear development during embryogenesis, and is also upregulated in the myometrium of the uterus during pregnancy. Targeted disruption of the Hmx3 gene results in mice with abnormal circling behavior and severe vestibular defects owing t

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19

Suh, Myung Whan, Dong Hoon Shin, Ho Sun Lee, Ji Yeong Park, Chong Sun Kim, and Seung Ha Oh. "WDR1 expression in the normal and noise-damaged chick vestibule." Journal of Vestibular Research 17, no. 4 (2008): 163–70. http://dx.doi.org/10.3233/ves-2007-17402.

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Unlike mammals, avian cochlear hair cells can regenerate after acoustic overstimulation. The WDR1 gene is one of the genes suspected to play an important role in this difference. In an earlier study, we found that the WDR1 gene is over-expressed in the chick cochlea after acoustic overstimulation. The aim of this study was to compare the expression of WDR1 before and after acoustic overstimulation in the chick vestibule. Seven-day-old chicks were divided into three groups: normal group, damage group, and regeneration group. The damage and regeneration group was exposed to 120 dB SPL white nois

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20

Okuno, Taeko, and Isamu Sando. "Localization, Frequency, and Severity of Endolymphatic Hydrops and the Pathology of the Labyrinthine Membrane in Meniere's Disease." Annals of Otology, Rhinology & Laryngology 96, no. 4 (1987): 438–45. http://dx.doi.org/10.1177/000348948709600418.

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The localization, frequency, and severity of endolymphatic hydrops in 22 temporal bones of 16 individuals with Meniere's disease were studied histopathologically. Endolymphatic hydrops was more often observed in the pars inferior (22/22) than in the pars superior (13/22) of the temporal bone, and severe hydrops was observed most frequently in the saccule, followed by the cochlea, the utricle, and the three semicircular canals. In the cochlea, the most severe hydrops was observed in the apical turn, followed by the hook portion, the middle turn, and the basal turn. Clinically interesting observ

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21

Jacobson, Gary P., Devin L. McCaslin, Erin G. Piker, Jill Gruenwald, Sarah L. Grantham, and Lauren Tegel. "Patterns of Abnormality in cVEMP, oVEMP, and Caloric Tests May Provide Topological Information about Vestibular Impairment." Journal of the American Academy of Audiology 22, no. 09 (2011): 601–11. http://dx.doi.org/10.3766/jaaa.22.9.5.

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Background: The cervical vestibular evoked myogenic potential (cVEMP) is recorded from the sternocleidomastoid muscle (SCM) and represents a stimulus-evoked attenuation of electromyographic (EMG) activity following activation of the saccule and inferior vestibular nerve. In addition to the cVEMP, it is possible to record a biphasic response from the infraorbital region following stimulation that is identical to that used to record the cVEMP. This response is known as the ocular VEMP (oVEMP). The peripheral vestibular origins of the oVEMP elicited with air conduction remain controversial as som

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22

Zakir, M., D. Huss, and J. D. Dickman. "Afferent Innervation Patterns of the Saccule in Pigeons." Journal of Neurophysiology 89, no. 1 (2003): 534–50. http://dx.doi.org/10.1152/jn.00817.2001.

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The innervation patterns of vestibular saccular afferents were quantitatively investigated in pigeons using biotinylated dextran amine as a neural tracer and three-dimensional computer reconstruction. Type I hair cells were found throughout a large portion of the macula, with the highest density observed in the striola. Type II hair cells were located throughout the macula, with the highest density in the extrastriola. Three classes of afferent innervation patterns were observed, including calyx, dimorph, and bouton units, with 137 afferents being anatomically reconstructed and used for quanti

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23

Meiteles, Lawrence Z., and Yehoash Raphael. "Distribution of Cytokeratins in the Vestibular Epithelium of the Guinea Pig." Annals of Otology, Rhinology & Laryngology 103, no. 2 (1994): 149–55. http://dx.doi.org/10.1177/000348949410300212.

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Cytokeratin expression in the vestibular labyrinth of the guinea pig was investigated with immunofluorescence and immunoperoxidase staining on surface preparations of the vestibular epithelium. Phalloidin, an F-actin—specific probe, was used to distinguish between hair cells and supporting cells. Cytokeratin expression was not found in the cytoplasmic domain of hair cells of the crista ampullaris, utricle, or saccule. Cytokeratin expression was abundant in supporting cells of the vestibular sensory epithelium. Electron microscopy revealed the presence of desmosomes, which are associated with c

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Pender, D. J. "Endolymphatic hydrops and Ménière's disease: a lesion meta-analysis." Journal of Laryngology & Otology 128, no. 10 (2014): 859–65. http://dx.doi.org/10.1017/s0022215114001972.

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AbstractObjective:To determine whether the distribution of membrane lesions associated with Ménière's disease is random, as might be expected from a pervasive process such as hydrops, or orderly, as might be expected if membrane resistance is graded.Method:A meta-analysis of temporal bone reports on 184 specimens demonstrating endolymphatic hydrops was undertaken to determine membrane lesion evolution and distribution.Results:Lesion distribution was found to be orderly and cochleocentric. No random scattershot lesions were reported in any study. Disease always started in the cochlear apex, eve

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Ishibe, Tsukasa, Michael A. Cremer, and T. J. Yoo. "Type II Collagen Distribution in the Ear of the Guinea Pig Fetus." Annals of Otology, Rhinology & Laryngology 98, no. 8 (1989): 648–54. http://dx.doi.org/10.1177/000348948909800816.

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By using monoclonal antibodies to type II collagen and immunohistochemical techniques, we studied the distribution of type II collagen in the developing guinea pig ear. Type II collagen appearance and disappearance corresponded to cartilage development and resorption. Type II collagen was identified in Meckel's and Reichert's cartilages, the cartilage plate of the auricle and external acoustic meatus, the ossicles, eustachian tube cartilage, and the otic capsule. Type II collagen also appeared with the development of structures in noncartilaginous parts including the tympanic membrane, tympani

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26

Saidel, William M., Joelle C. Presson, and Janet S. Chang. "S-100 immunoreactivity identifies a subset of hair cells in the utricle and saccule of a fish." Hearing Research 47, no. 1-2 (1990): 139–46. http://dx.doi.org/10.1016/0378-5955(90)90171-k.

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27

López-Escámez, J. A., P. V. Crespo, F. J. Cañizares, and A. Campos. "Dependence between saccule and utricle in Ca and K concentrations determined by electron probe X-ray microanalysis." Micron and Microscopica Acta 23, no. 3 (1992): 367–68. http://dx.doi.org/10.1016/0739-6260(92)90048-i.

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28

Chaves, Patrícia P., Ciara M. C. Valdoria, M. Clara P. Amorim, and Raquel O. Vasconcelos. "Ontogenetic development of the inner ear saccule and utricle in the Lusitanian toadfish: Potential implications for auditory sensitivity." Hearing Research 353 (September 2017): 112–21. http://dx.doi.org/10.1016/j.heares.2017.06.008.

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29

Mukherjee, Payal, Hilal Uzun, Ian Curthoys, and David Pohl. "(10) Three-Dimensional Analysis of The Anatomy of the Stapes Footplate in Relation to the Utricle and Saccule." Otolaryngology - Head and Neck Surgery 143, no. 5 (2010): S45—S46. http://dx.doi.org/10.1016/j.otohns.2010.08.043.

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Cohen, G. M., J. S. Grasso, M. L. Domeier, and P. T. Mangonon. "Improved preservation of the otolithic membranes." Proceedings, annual meeting, Electron Microscopy Society of America 45 (August 1987): 914–15. http://dx.doi.org/10.1017/s0424820100128857.

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Any explanation of vestibular micromechanics must include the roles of the otolithic and cupular membranes. However, micromechanical models of vestibular function have been hampered by unresolved questions about the microarchitectures of these membranes and their connections to stereocilia and supporting cells. Otolithic membranes are notoriously difficult to preserve because of severe shrinkage and loss of soluble components. We have empirically developed fixation procedures that reduce shrinkage artifacts and more accurately depict the spatial relations between the otolithic membranes and th

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Hara, Makoto, and Robert S. Kimura. "Morphology of the Membrana Limitans." Annals of Otology, Rhinology & Laryngology 102, no. 8 (1993): 625–30. http://dx.doi.org/10.1177/000348949310200811.

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The morphology of the membrana limitans (ML) was studied by light and electron microscopy to further understand its functional significance. The ML is a porous shield composed of a few to several layers of tightly packed fibrocytes that separate the perilymphatic space of the cochlea and saccule from that of the utricle and canal system. These fibrocytes are thinner on the side of the vestibule. They show many desmosomes and gap junctions and are interspersed with fibrils. The 3-dimensional reconstruction from celloidin sections shows that the ML, as it is viewed from the anterior side, is rec

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Olds, Michael J., and Michael J. Lyon. "Glucose Utilization of the Rat Vestibular End Organs: A Quantitative 2-Deoxyglucose Study." Annals of Otology, Rhinology & Laryngology 106, no. 2 (1997): 145–50. http://dx.doi.org/10.1177/000348949710600210.

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The local metabolic rate of glucose utilization (LMRglc) for the rat vestibular end organs was determined with a modification of the [14C]deoxyglucose method. Data are expressed as micromoles per 100 g per minute ± SEM. Results indicate that the LMRglc is similar within the utricle (40.3 ± 3.2) and saccule (41.2 ± S.5) and significantly higher than that for the superior (20.1 ± 2.9), posterior (25.4 ± 2.0), or lateral canal (22.0 ± 2.6) ampullae. These differences in LMRglc may be related to differences in the ratios of sensory to nonsensory cells, dark cell distributions, response to acoustic

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Bergstrom, Rebecca A., Yun You, Lawrence C. Erway, Mary F. Lyon, and John C. Schimenti. "Deletion Mapping of the Head Tilt (het) Gene in Mice: A Vestibular Mutation Causing Specific Absence of Otoliths." Genetics 150, no. 2 (1998): 815–22. http://dx.doi.org/10.1093/genetics/150.2.815.

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Abstract Head tilt (het) is a recessive mutation in mice causing vestibular dysfunction. Homozygotes display abnormal responses to position change and linear acceleration and cannot swim. However, they are not deaf. het was mapped to the proximal region of mouse chromosome 17, near the T locus. Here we report anatomical characterization of het mutants and high resolution mapping using a set of chromosome deletions. The defect in het mutants is limited to the utricle and saccule of the inner ear, which completely lack otoliths. The unique specificity of the het mutation provides an opportunity

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Johnson Chacko, Lejo, Consolato Sergi, Theresa Eberharter, et al. "Early appearance of key transcription factors influence the spatiotemporal development of the human inner ear." Cell and Tissue Research 379, no. 3 (2019): 459–71. http://dx.doi.org/10.1007/s00441-019-03115-6.

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AbstractExpression patterns of transcription factors leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5), transforming growth factor-β-activated kinase-1 (TAK1), SRY (sex-determining region Y)-box 2 (SOX2), and GATA binding protein 3 (GATA3) in the developing human fetal inner ear were studied between the gestation weeks 9 and 12. Further development of cochlear apex between gestational weeks 11 and 16 (GW11 and GW16) was examined using transmission electron microscopy. LGR5 was evident in the apical poles of the sensory epithelium of the cochlear duct and the vestibular end org

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Meyer, Michaela, Arthur N. Popper, and Richard R. Fay. "Coding of sound direction in the auditory periphery of the lake sturgeon, Acipenser fulvescens." Journal of Neurophysiology 107, no. 2 (2012): 658–65. http://dx.doi.org/10.1152/jn.00390.2011.

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The lake sturgeon, Acipenser fulvescens, belongs to one of the few extant nonteleost ray-finned fishes and diverged from the main vertebrate lineage about 250 million years ago. The aim of this study was to use this species to explore the peripheral neural coding strategies for sound direction and compare these results to modern bony fishes (teleosts). Extracellular recordings were made from afferent neurons innervating the saccule and lagena of the inner ear while the fish was stimulated using a shaker system. Afferents were highly directional and strongly phase locked to the stimulus. Direct

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Attyé, A., and M. Eliezer. "Endolymph magnetic resonance imaging: Contribution of saccule and utricle analysis in the management of patients with sensorineural ear disorders." European Annals of Otorhinolaryngology, Head and Neck Diseases 137, no. 1 (2020): 47–51. http://dx.doi.org/10.1016/j.anorl.2019.11.001.

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Friedman, R., N. Paradies, S. Wert, T. Doetschman, and E. L. Cardell. "The Effect of Tgfß-2 on Inner Ear Development: Light and Electron Microscopy Observations." Microscopy and Microanalysis 3, S2 (1997): 173–74. http://dx.doi.org/10.1017/s1431927600007753.

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Transforming growth factor beta (TGFß) genes are linked to a variety of developmental processes and are the subject of in vivo and in vitro transgene research studies. We are evaluating TGFß-2 effects on mouse inner ear development, with emphasis on the cochlear duct (CD), by comparing plastic sections of intact inner ears from developmental day (D) 16.5,18.5 and 19.5 littermates with wildtype (+/+), heterozygous (+/−) and mutant (−/−) TGFß-2 genotypes as determined by polymerase chain reaction analysis of tail digests. Auditory and vestibular organs of all D16.5 mice appear similar: membranou

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Schulz-Mirbach, Tanja, and Martin Plath. "All good things come in threes – species delimitation through shape analysis of saccular, lagenar and utricular otoliths." Marine and Freshwater Research 63, no. 10 (2012): 934. http://dx.doi.org/10.1071/mf12132.

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Otoliths are calcium carbonate biomineralisates in the inner ear of teleost fishes. Otoliths of the saccule (sagittae) are known to show species-specific (or even population-specific) contour differences and, thus, are regularly used in fisheries management for stock identification. However, the other two otolith types from the utricle (lapilli) and lagena (asterisci) are typically neglected in studies of this kind, such that little information is available regarding potential species-specific contour differences. Using four species of livebearing fishes of the genus Poecilia (Cyprinodontiform

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Schulz-Mirbach, Tanja, and Martin Plath. "Corrigendum to: All good things come in threes – species delimitation through shape analysis of saccular, lagenar and utricular otoliths." Marine and Freshwater Research 66, no. 8 (2015): 757. http://dx.doi.org/10.1071/mf12132_co.

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Otoliths are calcium carbonate biomineralisates in the inner ear of teleost fishes. Otoliths of the saccule (sagittae) are known to show species-specific (or even population-specific) contour differences and, thus, are regularly used in fisheries management for stock identification. However, the other two otolith types from the utricle (lapilli) and lagena (asterisci) are typically neglected in studies of this kind, such that little information is available regarding potential species-specific contour differences. Using four species of livebearing fishes of the genus Poecilia (Cyprinodontiform

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Sun, Yini, Allison Coltisor, Gary P. Jacobson, and Richard A. Roberts. "Case Study: Depersonalization and Vestibular Impairment." Journal of the American Academy of Audiology 32, no. 05 (2021): 324–30. http://dx.doi.org/10.1055/s-0041-1723040.

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Abstract Background We describe herein the case of a patient whose primary complaints were episodic vertigo and “depersonalization,” a sensation of detachment from his own body. Purpose This case study aims to further clinical knowledge and insight into the clinical evaluation of vertiginous patients with complaints of depersonalization. Research Design This is a case study. Data Collection and Analysis A retrospective chart review of vestibular function testing done on a vertiginous patient with complaints of depersonalization was performed. Results Vestibular function testing revealed absent

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Raquib, Ahmed, Md Abdullah Al Harun, MA Matin, Dhiman Pramanik, and M. Muinul Hafiz. "Video Head Impulse Test (vHIT) and Vestibular Evoked Myogenic Potential (VEMP) Test for Assessment of Vertigo: Our Initial Experience." Bangladesh Journal of Otorhinolaryngology 26, no. 1 (2020): 5–9. http://dx.doi.org/10.3329/bjo.v26i1.47946.

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Introduction: Loss of balance causes the sensation of vertigo. Balance is maintained by vestibular afferent from labyrinth, eyes and proprioceptors and their central integration. For diagnosis of vertigo, along with history different vestibulometric tests can be done to identify the specific anatomical part that is involved. Material and methods: A cross sectional study was done among 82 patients who did video Head Impulse Test (vHIT) and among 75 patients who did Vestibular Evoked Myogenic Potential (VEMP) test at AudiovestibularCentre(AVC) at Bangladesh ENT Hospital Ltd. during the per

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Beisel, Kirk W., Yesha Wang-Lundberg, Adel Maklad, and Bernd Fritzsch. "Development and evolution of the vestibular sensory apparatus of the mammalian ear." Journal of Vestibular Research 15, no. 5-6 (2005): 225–41. http://dx.doi.org/10.3233/ves-2005-155-601.

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Herein, we will review molecular aspects of vestibular ear development and present them in the context of evolutionary changes and hair cell regeneration. Several genes guide the development of anterior and posterior canals. Although some of these genes are also important for horizontal canal development, this canal strongly depends on a single gene, Otx1. Otx1 also governs the segregation of saccule and utricle. Several genes are essential for otoconia and cupula formation, but protein interactions necessary to form and maintain otoconia or a cupula are not yet understood. Nerve fiber guidanc

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Germanà, Antonino, Maria Cristina Guerrera, Rosaria Laurà, et al. "Expression and Localization of BDNF/TrkB System in the Zebrafish Inner Ear." International Journal of Molecular Sciences 21, no. 16 (2020): 5787. http://dx.doi.org/10.3390/ijms21165787.

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Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is involved in multiple and fundamental functions of the central and peripheral nervous systems including sensory organs. Despite recent advances in knowledge on the functional significance of BDNF and TrkB in the regulation of the acoustic system of mammals, the localization of BDNF/TrkB system in the inner ear of zebrafish during development, is not well known. Therefore, the goal of the present study is to analyze the age-dependent changes using RT-PCR, Western Blot and single and double immunofluorescence of the

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Liao, Yu-Hao, and Yi-Ho Young. "Inner Ear Damage by Firecracker Trauma." Audiology and Neurotology 23, no. 2 (2018): 116–21. http://dx.doi.org/10.1159/000492611.

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Firecrackers are still popular among the general public of various populations worldwide. This study investigated inner ear damage in patients with firecracker trauma and analyzed noise levels in 6 kinds of commercially available firecrackers. During the past 20 years, we have experienced 30 patients with firecracker trauma. An inner ear test battery comprising audiometry, cervical and ocular vestibular-evoked myogenic potential (cVEMP and oVEMP) tests and a caloric test was performed. The real-time noise levels were measured outdoors at a distance of 2, 4 and 6 m away from a lighting firecrac

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Bina, Alireza. "The link between Brain and Hearing system." Journal of Otolaryngology-ENT Research 12, no. 4 (2020): 114–17. http://dx.doi.org/10.15406/joentr.2020.12.00467.

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There are some studies which confirmed that dysfunction in Central Nervous System(CNS) may cause a malfunction in the Peripheral Auditory system (Cochlea_ Auditory Nerve, Auditory Neuropathy), but the question is could Brain Disorder without any lesion in the Cochlea and/or Auditory nerve cause Sensorineural Hearing Loss? It means that the Audiogram shows that the patient suffers from sensorineural hearing loss but the site of the lesion is neither Sensory nor Neural while Brain may be involved in charge of this. And if the answer is yes then could we hear with our Brain and without Cochlea an

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Wubbels, R. J., H. A. A. de Jong, and J. van Marle. "Morphometric analysis of the vestibular sensory epithelia of young adult rat." Journal of Vestibular Research 12, no. 4 (2003): 145–54. http://dx.doi.org/10.3233/ves-2003-12401.

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The appearance of vestibular sensory cells and their progressive development has been the subject of many ontogenetic studies. Because deteriorating hair cells are supposed to play a role in balance disorders of the elderly, the final stage of development (i.e. senescence) has been investigated as well. It is generally assumed that the number of hair cells in crista ampullaris, saccule and utricle slowly but steadily decreases with age. However, actual data covering the period between maturation and senescence are scarce. In the present study, rat vestibular epithelia were labeled for actin an

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Bianchi, L. M., J. C. Conover, B. Fritzsch, T. DeChiara, R. M. Lindsay, and G. D. Yancopoulos. "Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice." Development 122, no. 6 (1996): 1965–73. http://dx.doi.org/10.1242/dev.122.6.1965.

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The generation of mice lacking specific neurotrophins permits evaluation of the trophic requirements of particular neuronal populations throughout development. In the present study, we examined the developing vestibulocochlear system to determine the time course of neurotrophin dependence and to determine whether competition occurred among developing cochlear or vestibular neurons for available amounts of either brain-derived neurotrophic factor (BDNF) or neurotrophin-4/5 (NT-4/5). Both cochlear and vestibular neurons were present in mice lacking NT-4/5. In contrast, vestibular neurons decreas

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Rohregger, M., and N. Dieringer. "Principles of Linear and Angular Vestibuloocular Reflex Organization in the Frog." Journal of Neurophysiology 87, no. 1 (2002): 385–98. http://dx.doi.org/10.1152/jn.00404.2001.

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We compared the spatial organization patterns of linear and angular vestibuloocular reflexes in frogs by recording the multiunit spike activity from cranial nerve branches innervating the lateral rectus, the inferior rectus, or the inferior obliquus eye muscles. Responses were evoked by linear horizontal and/or vertical accelerations on a sled or by angular accelerations about an earth-vertical axis on a turntable. Before each sinusoidal oscillation test in darkness, the static head position was systematically altered to determine those directions of horizontal linear acceleration and those pl

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Xia, Gao. "R449 – The Role of DPZF in Inner Ear Development and Function." Otolaryngology–Head and Neck Surgery 139, no. 2_suppl (2008): P195. http://dx.doi.org/10.1016/j.otohns.2008.05.605.

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Problem The dendritic cell-derived BTB/POZ zinc finger (DPZF) protein belongs to the C2H2 zinc finger protein transcription factor family. It is localized on chromosome 3 and widely expressed in hematopoietic tissues, including human dendritic cells (DC), monocytes, B cells and T cells. DPZF null mice (DPZF-/-) exhibit a circling phenotype, suggestive of an inner ear defect. Here, we present our work on the role of DPZF in hearing defects. Methods We used auditory brainstem responses (ABR) and distortion production otoacoustic emissions (DPOAEs) to test the hearing function of DPZF-/- mice, th

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Lustig, Lawrence R., Hakim Hiel та Paul A. Fuchs. "Vestibular hair cells of the chick express the nicotinic acetylcholine receptor subunit α9". Journal of Vestibular Research 9, № 5 (1999): 359–67. http://dx.doi.org/10.3233/ves-1999-9505.

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The efferent cholinergic pathways to the vestibular periphery have yet to be fully characterized. While the nicotinic acetylcholine receptor subunit (nAChR) α9 is now regarded as the principle receptor for efferent cholinergic signaling to the organ of Corti, there is still uncertainty over how the more complex efferent effects of the labyrinth are produced. Recent experimental work has demonstrated that the nAChR α9 is present in the vestibular end-organs of the rat and mouse, suggesting that α9 may be one of the mediators of efferent cholinergic signaling in the vestibular periphery as well.

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