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Journal articles on the topic 'SAP( Severe Acute Pancreatitis) APACHE II Ranson score BISAP Score'

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Published: 5 June 2025

Last updated: 2 August 2025

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1

Dr. Girish S.P. and Dr. Sainani Rahul Raju. "Clinical Prediction of outcomes in Acute Pancreatitis with Various Prognostic Indicators and Modified CTSI." IAR Journal of Medicine and Surgery Research 1, no. 3 (2020): 41–45. http://dx.doi.org/10.47310/iarjmsr.2020.v01i03.10.

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Introduction: Acute pancreatitis is the most common cause of patients presenting to the emergency department with pain abdomen. It is an inflammatory process of the pancreas that can range from mild inflammation to severe extensive pancreatic necrosis and multi-organ failure with mortality rates of 20% to 30%. Diagnosis can be difficult, because there is no pathognomic clinical presentation and no diagnostic gold standard. Material and Methods: It was a prospective cross-sectional descriptive study conducted in the Department of Gastroenterology at Sapthagiri Institute of Medical Sciences and

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Khanna, Ajay K., Susanta Meher, Shashi Prakash, et al. "Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI Scores, IL-6, CRP, and Procalcitonin in Predicting Severity, Organ Failure, Pancreatic Necrosis, and Mortality in Acute Pancreatitis." HPB Surgery 2013 (September 24, 2013): 1–10. http://dx.doi.org/10.1155/2013/367581.

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Background. Multifactorial scorings, radiological scores, and biochemical markers may help in early prediction of severity, pancreatic necrosis, and mortality in patients with acute pancreatitis (AP). Methods. BISAP, APACHE-II, MOSS, and SIRS scores were calculated using data within 24 hrs of admission, whereas Ranson and Glasgow scores after 48 hrs of admission; CTSI was calculated on day 4 whereas IL-6 and CRP values at end of study. Predictive accuracy of scoring systems, sensitivity, specificity, and positive and negative predictive values of various markers in prediction of severe acute p

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Xu, Ruoxin, Ju Gong, Wei Chen, Yakang Jin, and Jian Huang. "Soluble B7-H5 Is a Novel Diagnostic, Severity, and Prognosis Marker in Acute Pancreatitis." BioMed Research International 2021 (October 8, 2021): 1–8. http://dx.doi.org/10.1155/2021/1223850.

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As an important ligand in T lymphocyte costimulatory pathways, B7-H5 is involved deeply in the immune response in various diseases. However, its clinical usefulness as an early indicator in acute pancreatitis (AP) remains unclear. In this study, the levels of sB7-H5 and cytokines in plasma samples of 75 AP patients, 20 abdominal pain patients without AP, and 20 healthy volunteers were determined. Then, the correlation of sB7-H5 and clinical features, cytokines, the Ranson score, APACHE II score, Marshall score, and BISAP score was analysed, and the value of sB7-H5 for diagnostic, severity, and

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4

a, Akshay, Basavaraj R. Patil, and Vinod V. Sangavi. "A STUDY OF SERUM CALCIUM AND SERUM ALBUMIN LEVELS IN PREDICTING SEVERITY OF ACUTE PANCREATITIS." International Journal of Advanced Research 11, no. 01 (2023): 1598–608. http://dx.doi.org/10.21474/ijar01/16183.

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Background:Acute Pancreatitis (AP) is an acute inflammatory process of the pancreas that affects other regional tissues and more distant organ system through the systemic inflammatory response , resulting in organ dysfunction and death. Only Minority patients will develop a severe disease , while most patients suffer from a mild ,self limiting inflammatory process.About 10 to 20% of patients will progress to Severe Acute Pancreatitis (SAP) with a mortality rate of 6 to 10 %. Serum calcium and serum albumin obtained within the first 24 hours of hospital admission are useful predictors of severi

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Mahajan, Ojas, Satish Mahajan, Sourya Acharya, et al. "A comparative evaluation of different scores in predicting severity and outcome in acute pancreatitis." F1000Research 12 (July 13, 2023): 824. http://dx.doi.org/10.12688/f1000research.133278.1.

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Background: Acute pancreatitis (AP) is an inflammatory condition usually caused by alcohol or gallstones. Our goal was to prospectively compare the diagnostic efficacy of the Acute Physiology & Chronic Health Evaluation (APACHE) II, the Bedside Index of Severity in Acute Pancreatitis (BISAP), the Ranson's score & the Modified Glasgow Score (MGS) in determining the severity & outcome of Acute pancreatitis in a tertiary care facility in central India. Methods: Between December 2020 & December 2022, this prospective observational study was done in rural area of Wardha district. 11

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Dr., Velmurugan S., (Prof.) T.R. Khurana Dr., and (Prof.) Shibani Mehra Dr. "Evaluation of the severity of acute pancreatitis using BISAP, Ranson and APACHE II scores and comparing them with Modified Computed Tomography Severity Index score." International Multispeciality Journal of Health 7, no. 10 (2021): 07–13. https://doi.org/10.5281/zenodo.5624782.

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<strong>Abstract</strong><strong>—</strong> <strong>Aims and Objectives:</strong> Most of the studies published so far compare one or two out of the three clinical scores for assessing the severity of acute pancreatitis namely BISAP, Ranson and APACHE II scores with the Radiological Score of Modified Computed Tomography Severity Index. There is a paucity of studies that compare all three Clinical Scores with the Radiological Score of Modified Computed Tomography Severity Index. The aim of this study is to compare all three clinical scores with the radiological score mentioned above. <str

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Theerthegowda, Akhila Nallur, Pavithra Umashankar, and Nagashri Suresh Iyer. "A Comparative Study between Bedside Index for Severity in Acute Pancreatitis (BISAP) and Acute Physiology and Chronic Health Evaluation (APACHE-II) Scoring System in Assessing the Severity of Acute Pancreatitis at Bangalore Medical College and Research Institute, Bangalore, India." Journal of Evidence Based Medicine and Healthcare 8, no. 36 (2021): 3269–75. http://dx.doi.org/10.18410/jebmh/2021/594.

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BACKGROUND Acute pancreatitis (AP) is an inflammatory disease of the pancreas, that results from intrapancreatic activation, release, and digestion of the organ by its own enzymes. The diagnosis of acute pancreatitis can be made when a patient presents with threefold elevated serum levels of amylase or lipase, abdominal pain and vomiting. In this study, we wanted to assess the severity of acute pancreatitis by using BISAP (Bedside index for severity in acute pancreatitis) and APACHE-II (Acute physiology and chronic health evaluation) scoring systems and compare the accuracy of BISAP scores wit

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8

Sehgal, Rishabh, Inder Pal Singh та Jyotisterna Mittal. "Clinical Proﬁle and Outcome of Patients with Severe Acute Pancreatitis". Asian Journal of Medical Research 9, № 3 (2020): 8–11. http://dx.doi.org/10.47009/ajmr.2020.9.3.me2.

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Background: Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas leading to pancreatic autodigestion. The present study was conducted to study the clinical profile and outcome of patients with severe acute pancreatitis. Subjects & Methods: The study was conducted on 40 patients of acute pancreatitis. Clinical profile including history, examination findings, etiology of pancreatitis, clinical severity (according to Modified Marshall Score, BISAP score, APACHE II, HAPS score, SOFA score) was recorded. Results: Severe Acute Pancreatitis (SAP) among patients. Majority of

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Yang, Lixin, Jing Liu, Yun Xing, et al. "Comparison of BISAP, Ranson, MCTSI, and APACHE II in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients." Gastroenterology Research and Practice 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/1834256.

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In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local c

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Chen, Lifen, Guomin Lu, Qunyan Zhou, and Qiang Zhan. "Evaluation of the BISAP Score in Predicting Severity and Prognoses of Acute Pancreatitis in Chinese Patients." International Surgery 98, no. 1 (2013): 6–12. http://dx.doi.org/10.9738/0020-8868-98.1.6.

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Abstract The present study was to evaluate the accuracy of bedside index for severity in acute pancreatitis (BISAP) in predicting the severity and prognoses of acute pancreatitis (AP) in Chinese patients. Clinical data for 497 patients with AP were analyzed retrospectively to compare BISAP with acute physiology and chronic health evaluation II, Ranson, and computed tomography severity index scores in predicting the severity of AP and the occurrence of pancreatic necrosis, mortality, and organ failure in patients with severe AP (SAP) using the area under the receiver-operating characteristic cu

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11

JAIN, Deepak, Gourab BHADURI, and Promil JAIN. "DIFFERENT SCORING SYSTEMS IN ACUTE ALCOHOLIC PANCREATITIS: WHICH ONE TO FOLLOW? AN ONGOING DILEMA." Arquivos de Gastroenterologia 56, no. 3 (2019): 280–85. http://dx.doi.org/10.1590/s0004-2803.201900000-53.

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ABSTRACT BACKGROUND: Acute pancreatitis is a common disorder in medical practice. In recent times, management has changed drastically with majority of decisions like intravenous antibiotics, negative suction with Ryle’s tube and surgical interventions like necrosectomy etc based on severity of the disease. There are different scores in use to assess severity of disease but the relative efficacy has remained a debatable subject. OBJECTIVE: The present study was thus done to investigate the predictive accuracy of different scoring systems in acute pancreatitis. METHODS: Fifty patients of acute p

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.., Gulamnabi, and P. Sudarshan. "Validation of Bisap Scoring System in Predicting the Severity of Acute Pancreatitis according to the Latest Atlanta Classification." New Indian Journal of Surgery 9, no. 4 (2018): 524–31. http://dx.doi.org/10.21088/nijs.0976.4747.9418.24.

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Acute pancreatitis (AP) is an inflammatory condition of the pancreas with a clinical course hat varies from mild to severe, leading to activation of pancreatic enzyme and causing selfdigestion of the pancreas. The overall mortality rate of AP is 2–5%, but the mortality of severe acute pancreatitis (SAP) may range upto 20–30%. So it is important to assess the disease severity in a timely and accurate manner There are variety of score systems such as Ransom’s criteria[1], Acute Physiology and Chronic Health Evaluation (APACHE) II [2] and Computed Tomography Severity Index (CTSI). But these syste

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Wang, Yu, Guangbo Qu, Zhangbi Wu, et al. "Early predictive value of scoring systems and routine laboratory tests in severity and prognosis of acute pancreatitis in pregnancy." Therapeutic Advances in Gastroenterology 16 (January 2023): 175628482311672. http://dx.doi.org/10.1177/17562848231167277.

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Background: Currently, no guidelines specifically recommend scoring systems and biomarkers for early evaluation of the severity and prognosis of acute pancreatitis in pregnancy (APIP). Objectives: This study aimed to explore the early predictive value of scoring systems and routine laboratory tests on APIP severity and maternofetal prognosis. Design: This study retrospectively analyzed 62 APIP cases in a 6-year period. Methods: The predictive value of scoring systems and routine laboratory tests that were collected 24 h and 48 h after admission, for APIP severity and fetal loss, were analyzed.

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Baykan, A. R., I. Baydar, E. Şebin, et al. "Can we use endocan level to determine severity of pancreatitis?" Acta Gastro Enterologica Belgica 84, no. 2 (2021): 321–25. http://dx.doi.org/10.51821/84.2.321.

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Background and study aims: Endothelial cell specific molecule-1 (ESM-1), also known as endocan, is a soluble proteoglycan secreted by human vascular endothelial cells. In some studies, it has been found that endocan have important effects on cell adhesion, inflammation and angiogenesis. In this study, we aimed to evaluate the endocan level in patients with pancreatitis and the availability of endocan level in determining the severity of the disease. Patients and methods: A total of 42 patients with pancreatitis and 33 healthy individuals were included in the study. The serum endocan levels in

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15

Amália Cinthia Meneses do Rêgo and Irami Araújo-Filho. "Decision-making in severe acute pancreatitis: The role of artificial intelligence and severity scales." World Journal of Advanced Research and Reviews 23, no. 1 (2024): 2899–908. http://dx.doi.org/10.30574/wjarr.2024.23.1.2255.

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Severe acute pancreatitis (SAP) presents a complex clinical scenario that demands prompt and accurate decision-making regarding the appropriate course of treatment. The management of SAP involves a delicate balance between surgical intervention and conservative therapy, aiming to optimize patient outcomes while minimizing morbidity and mortality. Traditional methods of assessing disease severity, such as the Balthazar scale, Ranson criteria, Glasgow-Imrie score, and APACHE II score, provide valuable clinical insight but may lack the precision necessary for individualized patient care. In recen

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Araujo-Filho, Irami, and Amália Cinthia Menseses Rêgo. "Decision-Making in Severe Acute Pancreatitis: The role of Artificial Intelligence and Severity Scales." JOURNAL OF SURGICAL AND CLINICAL RESEARCH 15, no. 2 (2024): 173–86. https://doi.org/10.21680/2179-7889.2024v15n2id36173.

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Severe acute pancreatitis (SAP) presents a complex clinical scenario that demands prompt and accurate decision-making regarding the appropriate course of treatment. The management of SAP involves a delicate balance between surgical intervention and conservative therapy, aiming to optimize patient outcomes while minimizing morbidity and mortality. Traditional methods of assessing disease severity, such as the Balthazar scale, Ranson criteria, Glasgow-Imrie score, and APACHE II score, provide valuable clinical insight but may lack the precision necessary for individualized patient care. In recen

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Amália, Cinthia Meneses do Rêgo, and Araújo-Filho Irami. "Decision-making in severe acute pancreatitis: The role of artificial intelligence and severity scales." World Journal of Advanced Research and Reviews 23, no. 1 (2024): 2899–908. https://doi.org/10.5281/zenodo.14830484.

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Severe acute pancreatitis (SAP) presents a complex clinical scenario that demands prompt and accurate decision-making regarding the appropriate course of treatment. The management of SAP involves a delicate balance between surgical intervention and conservative therapy, aiming to optimize patient outcomes while minimizing morbidity and mortality. Traditional methods of assessing disease severity, such as the Balthazar scale, Ranson criteria, Glasgow-Imrie score, and APACHE II score, provide valuable clinical insight but may lack the precision necessary for individualized patient care. In recen

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18

Yadav, Satish Chandra, and Bingqiang Zhang. "Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications." Gastroenterology Research and Practice 2022 (March 7, 2022): 1–8. http://dx.doi.org/10.1155/2022/7575231.

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Objective. To compare the conventional treatment and continuous veno-venous haemofiltration (CVVH) in severe acute pancreatitis (SAP) for the prevention of pseudocyst and walled-off necrosis. Patients and Methods. Forty-two patients were divided into two treatment groups: conventional treatment group contained 24 patients and CVVH had 18. Conventional treatment group patients were treated symptomatically and according to the causes. CVVH group patients were treated symptomatically, and CVVH was done within 2 hours of admission. Results. In both groups, there was a decrease in amylase, lipase,

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Tsiampas, Ioannis. "Management of acute pancreatitis in the Emergency Department." Health & Research Journal 8, no. 4 (2022): 325–37. http://dx.doi.org/10.12681/healthresj.31560.

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Background: Heterogeneity in clinical manifestations and outcome of pancreatitis constitutes an obstacle for the creation of a common treatment algorithm by the scientific community. Aim: The aim of the present study was to systematically review the management of cases of acute pancreatitis in Emergency Department (ED) and her correlation with outcome. Methods: Search the database Pubmed and were included observational studies and randomized trials in adults in English. Results: The search yielded 13 studies. Of these, 3 concerned the diagnostic approach of the disease in ED

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Wu, Hongsheng, Keqiang Ma, Biling Liao, Tengfei Ji, Shengmin Zhang, and Tiansheng Cao. "Comparative Analysis of Early Clinical Features and Complications of Different Types of Acute Pancreatitis." Oxidative Medicine and Cellular Longevity 2022 (June 25, 2022): 1–9. http://dx.doi.org/10.1155/2022/3771610.

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Background. Acute pancreatitis (AP) is a common surgical acute abdomen. Different kinds of pancreatitis may have different pathophysiological characteristics each other. The objective of this research was to investigate the early clinical features and complications of different types of acute pancreatitis. Methods. 787 AP patients admitted in the Huadu District People’s Hospital of Guangzhou during January 2009 and December 2019 were analyzed retrospectively. Among 787 AP patients, 520 (66.1%) were biliary AP (group I), 69 (8.7%) were alcoholic AP (group II), and 198 (25.2%) were hypertriglyce

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Chooklin, S., B. Pidhirnyi, and R. Barylyak. "Soluble Fibrin-monomeric Complexes and D-dimers as Indicators of Acute Pancreatitis Severity." Lviv clinical bulletin 3-4, no. 39-40 (2023): 26–32. http://dx.doi.org/10.25040/lkv2022.03-04.026.

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Introduction. Local and systemic inflammation, disorders in the hemostatic system are among the key components of acute pancreatitis (AP) pathogenesis already in its early stages, and in future development of thrombohemorrhagic complications. The degree of systemic hemostatic disorders in AP varies from subclinical activation of coagulation, which can only be detected using sensitive markers of activation of coagulation factors, to fulminant disseminated intravascular coagulation syndrome, characterized by multiple systemic microvascular thrombosis and profuse bleeding from different sites. It

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Capurso, Gabriele, Ruggero Ponz de Leon Pisani, Gaetano Lauri, et al. "Clinical usefulness of scoring systems to predict severe acute pancreatitis: A systematic review and meta‐analysis with pre and post‐test probability assessment." United European Gastroenterology Journal, September 27, 2023. http://dx.doi.org/10.1002/ueg2.12464.

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AbstractBackgroundScoring systems for severe acute pancreatitis (SAP) prediction should be used in conjunction with pre‐test probability to establish post‐test probability of SAP, but data of this kind are lacking.ObjectiveTo investigate the predictive value of commonly employed scoring systems and their usefulness in modifying the pre‐test probability of SAP.MethodsFollowing PRISMA statement and MOOSE checklists after PROSPERO registration, PubMed was searched from inception until September 2022. Retrospective, prospective, cross‐sectional studies or clinical trials on patients with acute pan

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Khandelwal, Apoorv, Nalini Joshi, and Rupam Joshi. "A STUDY ON THE EFFICACY OF THE BEDSIDE INDEX FOR SEVERITY IN ACUTE PANCREATITIS (BISAP) WITH THE RANSON AND APACHE II SCORING SYSTEMS IN PREDICTING OUTCOMES." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, December 1, 2024, 80–84. https://doi.org/10.36106/ijsr/4805950.

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Background: Acute pancreatitis is a prevalent inflammatory condition of the pancreas with a diverse etiology and a mortality rate ranging from 5% to 40% depending on severity. Effective early diagnosis and accurate assessment of disease severity are crucial for optimizing patient management. Objective: This study aims to compare the efficacy of the Bedside Index for Severity in Acute Pancreatitis (BISAP) with the Ranson and APACHE II scoring systems in predicting outcomes such as severity, organ failure, and mortality in patients with acute pancreatitis. A cohort of 50 Methods: patients diagno

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Akshay, R. Patil Basavaraj, and V. Sangavi Vinod. "A STUDY OF SERUM CALCIUM AND SERUM ALBUMIN LEVELS IN PREDICTING SEVERITY OF ACUTE PANCREATITIS." January 10, 2023. https://doi.org/10.5281/zenodo.7660558.

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<strong>Background</strong>:Acute Pancreatitis (AP) is an acute inflammatory process of the pancreas that affects other regional tissues and more distant organ system through the systemic inflammatory response , resulting in organ dysfunction and death. Only Minority patients will develop a severe disease , while most patients suffer from a mild ,self limiting inflammatory process.About 10 to 20% of patients will progress to Severe Acute Pancreatitis (SAP) with a mortality rate of 6 to 10 %. Serum calcium and serum albumin obtained within the first 24 hours of hospital admission are useful pre

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Gu, Kaier, Wenxuan Shang, and Dingzhou Wang. "Visceral obesity anthropometric indicators as predictors of acute pancreatitis severity." Frontiers in Medicine 12 (July 11, 2025). https://doi.org/10.3389/fmed.2025.1536090.

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BackgroundAcute pancreatitis (AP) severity assessment upon admission is crucial for prognosis, yet existing clinical scoring systems have limitations like delayed results, complexity, or low sensitivity. Obesity correlates with AP severity, but traditional body mass index (BMI) fails to accurately reflect visceral fat distribution. Although anthropometric indicators for visceral obesity offer alternatives, their predictive value for AP severity across all etiologies is poorly studied.MethodsThis retrospective cohort study analyzed 629 AP patients admitted to a tertiary hospital (2016–2023). Pa

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Pallavi, Kumari, M. K. Nathani, C. M. Narayan, and Debarshi Jana. "COMPARATIVE STUDY BETWEEN BISAP SCORE AND RANSON SCORE IN PREDICTING SEVERITY OF ACUTE PANCREATITIS." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, November 1, 2020, 16–17. http://dx.doi.org/10.36106/ijsr/8731067.

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Background: Acute pancreatitis has widely variable clinical and systemic manifestations spanning the spectrum from a mild, self-limiting episode of epigastric pain to severe, life-threatening, multiorgan failure. Since the morbidity and mortality of Acute Pancreatitis differ markedly between mild and severe disease (mild < 5% vs severe 20–25%), it is very important to assess severity as early as possible. Various scoring systems like APACHE II scoring, RANSON scoring and BISAP have been used to asses Severity in Acute Pancreatitis. Aim and objective: To assess the accuracy of BISAP scoring

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Shi, Pei-Na, Zhang-Zhang Song, Xu-Ni He, and Jie-Ming Hong. "Evaluation of scoring systems and hematological parameters in the severity stratification of early-phase acute pancreatitis." World Journal of Gastroenterology 31, no. 15 (2025). https://doi.org/10.3748/wjg.v31.i15.105236.

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BACKGROUND Acute pancreatitis (AP) is an emergency gastrointestinal disease that requires immediate diagnosis and urgent clinical treatment. An accurate assessment and precise staging of severity are essential in initial intensive therapy. AIM To explore the prognostic value of inflammatory markers and several scoring systems [Acute Physiology and Chronic Health Evaluation II, the bedside index of severity in AP (BISAP), Ranson’s score, the computed tomography severity index (CTSI) and sequential organ failure assessment] in severity stratification of early-phase AP. METHODS A total of 463 pat

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Talukdar, Mrinal, Prashanth K R, and Ratnadeep Paul. "D-DIMER - AN ESSENTIAL MARKER IN SEVERITY PREDICTION OF ACUTE PANCREATITIS." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, September 1, 2021, 78–82. http://dx.doi.org/10.36106/ijsr/0305204.

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Introduction: Acute pancreatitis (AP) is characterized by a spectrum of symptoms, ranging from a local inammatory process to the more severe form (acute necrotizing pancreatitis) which is associated with a systemic inammatory response. The overall mortality rate of AP is between 5% and 15%, reaching 30 % in severe acute pancreatitis (SAP). Early optimized care may improve prognosis in patients with severe forms but it remains a challenge to identify these poor prognosis cases especially in the rst 48 hours. This study will evaluate the efcacy of serum D-Dimer in prediction of severity and

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Wang, Fushuang, Minghui Zhu, Yao Meng, and Min Lin. "Serum soluble T cell immunoglobulin mucin domain-3 as an early predictive marker for severity of acute pancreatitis; a retrospective analysis." BMC Gastroenterology 22, no. 1 (2022). http://dx.doi.org/10.1186/s12876-022-02537-x.

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Abstract Background Early prediction of severe acute pancreatitis (SAP) plays an important role in timely treatment decisions. Soluble T cell immunoglobulin and mucin domain-3 (sTIM-3) has been applied as a potential biomarker for the prediction of many diseases, while its predictive ability for AP severity remains largely unexplored. In this study, we aimed to identify whether serum sTIM-3 could be used as an indicator of AP severity in the early stage of the disease. Methods A retrospective study was conducted. The enrolled AP patients should meet the 2012 Atlanta guideline and have an onset

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LIANG, Yi, Xianwei ZHAO, and Fanliang MENG. "Procalcitonin, C-reactive Protein, and Neutrophil Ratio Contribute to the Diagnosis and Prognosis of Severe Acute Pancreatitis." Iranian Journal of Public Health, July 5, 2020. http://dx.doi.org/10.18502/ijph.v48i12.3548.

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Background: We aimed to explore the significance of procalcitonin (PCT), C-reactive protein (CRP) and neutrophil ratio (N%) in the early diagnosis, treatment, and prognosis of severe acute pancreatitis (SAP). Methods: A total of 104 patients with SAP (SAP group) and 101 patients with mild acute pancreatitis (MAP) (MAP group) admitted to Affiliated Hospital of Jining Medical University, Jining, China were enrolled. The PCT and CRP in serum were detected by a full-automatic biochemical analyzer, and N% in peripheral blood was measured by a hemocyte analyzer. Results: The peripheral b

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Shen, Dingcheng, Caixi Tang, Shuai Zhu, and Gengwen Huang. "Macrophage migration inhibitory factor is an early marker of severe acute pancreatitis based on the revised Atlanta classification." BMC Gastroenterology 21, no. 1 (2021). http://dx.doi.org/10.1186/s12876-020-01598-0.

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Abstract Background Various serum markers for early identification of severe acute pancreatitis (SAP) have been studied. Serum macrophage migration inhibitory factor (MIF) was reported to be correlated with severity of acute pancreatitis (AP) based on the 1992 Atlanta classification. However, MIF has never been proven to be predictive of disease severity based on the revised Atlanta classification (RAC). The potential predictive value of MIF needs to be further validated. Methods Consecutive patients with AP within 48 h after symptom onset and 10 healthy control volunteers were enrolled prospe

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AYDIN, Hakan, Fatih DOĞANAY, Mehmet ERDOĞAN, Halil DOĞAN, Attila BEŞTEMİR, and Alpay TUNCAR. "Comparison of CCI, BISAP and APACHE II Scoring Systems to Predict Severe Disease in Patients with Mild Acute Pancreatitis: A Retrospective Observational Study." Cumhuriyet Medical Journal, December 27, 2022. http://dx.doi.org/10.7197/cmj.1216327.

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Background: Early recognition and treatment of patients with acute pancreatitis (AP) is important to improve prognosis and increase survival. Many scoring systems have been developed to assess the prognosis and disease severity in AP. The aim of this study was to compare the effectiveness of the Charlson Comorbidity Index (CCI), Bedside Index for Severity in AP (BISAP), and Acute Physiology and Chronic Health Evaluation (APACHE II) scores in predicting 30-day mortality and the development of severe AP (SAP) in patients with mild AP (MAP). Materials and Methods: This single-center, retros

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Chooklin, S., B. Pidhirnyi, and R. Barylyak. "Soluble Fibrin-monomeric Complexes and D-dimers as Indicators of Acute Pancreatitis Severity." December 26, 2022. https://doi.org/10.25040/lkv2022.03-04.026.

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<strong>Introduction.</strong> Local and systemic inflammation, disorders in the hemostatic system are among the key components of acute pancreatitis (AP) pathogenesis already in its early stages, and in future development of thrombohemorrhagic complications. The degree of systemic hemostatic disorders in AP varies from subclinical activation of coagulation, which can only be detected using sensitive markers of activation of coagulation factors, to fulminant disseminated intravascular coagulation syndrome, characterized by multiple systemic microvascular thrombosis and profuse bleeding fr

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