Academic literature on the topic 'Saponines'

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Journal articles on the topic "Saponines"

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Gaidi, Ghezala, and Marie-Aleth Lacaille-Dubois. "Trois nouvelles saponines d’Arenaria juncea." Journal de la Société de Biologie 195, no. 4 (2001): 463–64. http://dx.doi.org/10.1051/jbio/2001195040463.

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Dembele, Daouda Lassine, Aimé Ainin Somboro, Sékou Doumbia, Mamadou Lamine Diarra, Mahamane Haïdara, and Sanogo Rokia. "Etude pharmacognosique des feuilles, écorces de racines, écorces de tronc et de la racine entière de <i>Securidaca longipeduncultata</i> Fresen (Polygalaceae), récoltées au Mali." International Journal of Biological and Chemical Sciences 17, no. 4 (September 19, 2023): 1701–16. http://dx.doi.org/10.4314/ijbcs.v17i4.32.

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Au Mali, les racines de Securidaca longipedunculata sont fortement utilisées et les peuplements de l’espèce se font de plus en plus rares. Ce travail visait à effectuer une étude comparative des paramètres pharmacognosiques des feuilles, écorces de tronc, écorces de racine et de la racine entière. Les échantillons ont été analysés pour déterminer les caractéristiques botaniques et physicochimiques. Des extraits aqueux et organiques ont été préparés pour caractériser les principaux constituants bioactifs par des techniques colorimétriques et chromatographiques. Les composés majoritaires ont été extraits par ultrasons et quantifiés. Les éléments botaniques communs étaient des fibres, cristaux d’oxalate de calcium, xylèmes et parenchymes. Des sclérites et fragments d’épiderme étaient seulement dans les feuilles. Le meilleur rendement d’extraction a été obtenu avec l’éthanol. Les principaux constituants étaient des tanins, flavonoïdes, coumarines, anthraquinones et saponines dans les feuilles ; des coumarines et saponines dans les écorces de tronc, écorces de racine et la racine entière. Les constituants majoritaires étaient des saponines triterpéniques dont 1,51 g de précipités enrichis ont été extraits à partir des écorces de racine. Les feuilles ont qualitativement présenté le plus de constituants bioactifs. Des investigations sont nécessaires pour évaluer leur efficacité afin de diminuer la pression sur les racines. English title: Pharmacognostic study of the leaves, root bark, trunk bark and whole root of Securidaca longipeduncultata Fresen (Polygalaceae), harvested in Mali In Mali, the roots of Securidaca longipedunculata are used extensively, and stands of the species are becoming increasingly are becoming increasingly rare. The aim of this work was to carry out a comparative study of the pharmacognosic parameters of leaves, trunk bark, root bark and the whole root. Samples were analyzed for botanical and physicochemical characteristics. Aqueous and organic extracts were prepared to characterize the main bioactive constituents using colorimetric and chromatographic techniques. Major compounds were ultrasonically extracted and quantified. Common botanical elements were fibers, calcium oxalate crystals, xylem and parenchyma. Sclerites and epidermal fragments were only found in leaves. The best extraction yield was obtained with ethanol. The main constituents were tannins, flavonoids, coumarins, anthraquinones and saponins in the leaves; coumarins and saponins in the trunk bark, root bark and whole root. The main constituents were triterpene saponins, of which 1.51 g of enriched precipitates were extracted from root barks. Leaves qualitatively presented the most bioactive constituents. Further investigations are needed to assess their effectiveness in reducing pressure on the roots.
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Benahmed-Djilali, A., T. Chemoul, S. Kal, M. Nabiev, and C. Besombes. "Propriétés d’une pommade antibactérienne formulée à base de saponines extraites des feuilles de noyer." Phytothérapie 16, S1 (December 2018): S245—S253. http://dx.doi.org/10.3166/phyto-2019-0152.

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Ce travail vise la valorisation des feuilles de noyer en tant qu’une des ressources agricoles algériennes. L’extraction des saponines à partir des feuilles de noyer a été réalisée en tant qu’une classe très intéressante de produits actifs ??? Ils sont identifiés comme des composés multifonctionnels, possédant plusieurs activités pharmacologiques. Le rendement en saponines obtenu est de 22,8 %dry basis(db). L’application de ces saponines dans des pommades antibactériennes a conduit à l’obtention de deux formulations jugées de bonne qualité sensorielle, physicochimique, rhéologique et microbiologique. Les deux pommades choisies peuvent être considérées comme des fluides plastiques, de type « fluide non newtonien pseudoplastique ». De plus, elles sont efficaces contre les bactéries Gram positif (Staphylococcus aureusATCC25923) et négatif (Escherichia coliATCC25322). Cependant, elles ne présentent pas d’activité antifongique contreAspergillus niger. La poudre de feuilles de noyer ainsi obtenue peut ainsi être considérée comme une substance naturelle de grande bioactivité potentielle. Elle pourra contribuer au développement de nouveaux produits industriels.
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Tine, Yoro, Moussa Diop, Idrissa Ndoye, Alioune Diallo, and Alassane Wele. "Revue bibliographique sur la composition chimique et les activités biologiques de Guiera senegalensis J.F. Gmel. (Combretaceae)." International Journal of Biological and Chemical Sciences 13, no. 7 (February 13, 2020): 3449–62. http://dx.doi.org/10.4314/ijbcs.v13i7.37.

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Cette étude avait pour objectif de faire le point sur la composition chimique et les activités biologiques de G. senegalensis, une plante médicinale largement utilisée en Afrique par les guérisseurs traditionnels pour le traitement de divers troubles. La plupart de ces études chimiques ont porté sur le criblage phytochimique des extraits de feuilles, de racines, de tiges et de galles. Elles ont montré la présence d'hydrates de carbone, de stéroïdes, de saponines, de flavonoïdes, d’alcaloïdes, de tanins, de saponines, de glycosides cardiaques, de coumarines, d’anthraquinones, d’acide ascorbique, d’hétérosides cardiotoniques, de cyanogènes et de terpénoïdes. Les potentialités thérapeutiques des extraits de G. senegalensis rapportées dans plusieurs travaux scientifiques ont porté sur les activités antibactériennes, antitussives, antidiarrhéiques, cytotoxiques, anti-inflammatoires antipaludiques, antitrypanosomiques, antihelminthiques, antivirales et antioxydantes. Des études de toxicité sur ces extraits ont été aussi réalisées. Ainsi, des études de caractérisation chimique (variabilité chimique), de formulation galénique et aussi de toxicité clinique sur G. senegalensis doivent être menées afin de mettre en place des produits de phytothérapie moderne.Mots clés: Phytochimie, pharmacologie, feuilles, Guiera senegalensis. English Title: Review on the chemical composition and biological activities of Guiera senegalensis J.F. Gmel. (Combretaceae)The aim of this study was to review the chemical composition and biological activities of G. senegalensis, a medicinal plant widely used in Africa by traditional healers for the treatment of various disorders. Most of these chemical studies have focused on the phytochemical screening of leaf, root, stem and gall extracts. They showed the presence of carbohydrate, steroids, saponins, flavonoids, alkaloids, tannins, saponins, cardiac glycosides, coumarins, anthraquinones, ascorbic acid, cardiotonic glycosides, cyanogens and terpenoids. The therapeutic potentialities of extracts of G. senegalensis reported in several scientific studies have focused on antibacterial, antitussive, antidiarrheal, cytotoxic, anti-inflammatory, antimicrobial, antitrypanosomal, anthelmintic, antiviral and antioxidant activities. Toxicity studies on these extracts have also been carried out. Thus, chemical characterization studies (chemical variability), galenic formulation and clinical toxicity studies on G. senegalensis must be carried out in order to implement modern phytotherapy products.Keywords: Phytochemistry, pharmacology, leaves, Guiera senegalensis.
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Tine, Yoro, Madièye Sene, Khadidiatou Thiam, Cheikhouna Gaye, Alioune Diallo, Benjamin Ndiaye, Idrissa Ndoye, et al. "Revue des usages traditionnels, composition chimique et propriétés pharmacologiques de <i>Combretum glutinosum</i> (Combretaceae)." International Journal of Biological and Chemical Sciences 17, no. 6 (January 18, 2024): 2475–89. http://dx.doi.org/10.4314/ijbcs.v17i6.27.

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Combretum glutinosum Perr. ex DC. (Combretaceae) est une plante médicinale largement utilisée en Afrique par les praticiens traditionnels pour le traitement de divers troubles comme les maladies respiratoires, la douleur, le paludisme et les infections microbiennes. En raison de sa large utilisation traditionnelle, dans cette revue, les rapports scientifiques publiés sur sa composition et ses propriétés pharmacologiques ont été explorés en effectuant une recherche documentaire dans les bases de données de Google Scholar, PubMed, Elsevier, ScienceDirect et Scifinder. Les études chimiques ont montré la présence de saponines, de flavonoïdes, d’alcaloïdes, de tanins, de saponines, de glycosides cardiaques, d’anthraquinones, d’acides aminés et de terpénoïdes. Il a été démontré que des extraits de cette plante ainsi que les composés purs qui en ont été isolés, possédaient des propriétés antibactérienne, antiparasitaire, antidiarrhéique, cytotoxique, anti-inflammatoire, hypoglycémiante, antioxydante, antihelminthique et antipaludique, entre autres. Cette revue fournit donc une vue d'ensemble des progrès actuels en matière, d'ethnopharmacologie, de phytochimie, de pharmacologie et de toxicité de C. glutinosum, constituant ainsi une référence pour la Recherche et Développement sur C. glutinosum. Combretum glutinosum Perr. ex DC. (Combretaceae) is a medicinal plant widely used in Africa by traditional practitioners for the treatment of various disorders such as respiratory diseases, pain, malaria and microbial infections. Due to its wide traditional use, in this review, published scientific reports on its composition and pharmacological properties were explored by conducting a literature search of Google Scholar, PubMed, Elsevier, ScienceDirect and Scifinder databases. Chemical studies showed the presence of saponins, flavonoids, alkaloids, tannins, saponins, cardiac glycosides, anthraquinones, amino acids, and terpenoids. Extracts of this plant, as well as the pure compounds isolated from it, have been shown to possess antibacterial, antiparasitic, antidiarrheal, cytotoxic, anti-inflammatory, hypoglycemic, antioxidant, antihelminthic and antimalarial properties, among others. This review therefore provides an overview of current progress in ethnopharmacology, phytochemistry, pharmacology and toxicity of C. glutinosum, thus constituting a reference for Research and Development on C. glutinosum.
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Moon, Beom-Hee, Ji-Sung Kang, and Hyang-Yeol Lee. "Review about Efficacies and Structures of Ginseng Saponines." Journal of Biotechnology and Bioindustry 9 (December 2021): 51–56. http://dx.doi.org/10.37503/jbb.2021.9.51.

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Ghamiaa, Abir, Zainab Oshah, Asra Al Shak, and Esam Elhefian. "Qualitative and Quantitative Phytochemical Analysis of Retama raetam (forssk) Leaves." Research Journal of Chemistry and Environment 27`, no. 10 (September 15, 2023): 67–71. http://dx.doi.org/10.25303/2710rjce067071.

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Retama raetam is widespread in North Africa and considered to be a medicinal plant in folk treatment besides its importance as feed for livestock. It has been used as herbal remedy for healing several ailments like diarrhea, skin rash, sore throat, rheumatism, fever and injury sterilization. This study was conducted to estimate the medicinal and nutritional values of R. reatam plant by determining some essential contents, minerals, vitamin C and preliminary phytochemical compounds in its leaves. The primary analysis showed that the pH value of water extract was 7.18 ± 0.03 while the percentages of essential contents in leaves were 50.83 ± 1.04 crude fiber, 12.33 ± 0.76 crud lipids, 6.02 ± 0.01 crude protein, 5.00 ± 0.00 total ash content, 10.00 ± 0.00 ash soluble in water, 5.00 ± 0.00 ash insoluble in acid and 19.67 ± 0.58 moisture content. Primary tests of the crude aqueous extract revealed the presence of tannins , saponines, alkaloids flavonoids, glycosides, resins, terpenoids and steroids, while the ethanolic extract showed positive results for tannins, alkaloids, flavonoids, glycosides, terpenoids and steroids, but negative results for saponines and resins. The percentages of phytochemical compounds in the air dried leaves powder were 5.67 ± 0.58 tannins, 10.42 ± 0.72 saponines, 8.33 ± 0.76 alkaloids and 9.80 ± 1.13 flavonoids. The amounts of minerals and vitamins (mg/100) that were determined in the R. raetam dried leaves powder were 333.75 ± 1.77 potassium, 501.25 ± 1.77 sodium, 235.50 ± 6.36 magnesium, 500.00 ± 0.00 calcium and 35.33 ± 0.29 vitamin C. The obtained results prove the traditional medicinal use of R. raetam in North and East Mediterranean regions. In addition, knowing the amounts of the essential components and bioactive compounds may help in the preparation of the exact dosages for the treatment of diseases or for livestock feeding.
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Diatta, B. D., O. Niass, M. Diouf, M. Guèye, E. Houel, and G. Boetsch. "Diversité et composition phytochimique des plantes utilisées comme bâtonnets frotte-dents (cure-dents) par les Peuls de la commune de Tessékéré (Ferlo Nord, Sénégal)." Phytothérapie 19, no. 1 (February 2021): 45–54. http://dx.doi.org/10.3166/phyto-2019-0161.

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Le bâtonnet frotte-dents est un outil d’hygiène buccodentaire en forme de fragment de matière végétale : tige, brindille, petite branche ou racine. Le but de cette étude était de déterminer la composition phytochimique et la teneur en grandes classes chimiques des tiges les plus utilisées comme bâtonnets frotte-dents chez les Peuls de Widou Thiengoli au Nord Ferlo (Sénégal). Des entretiens ouverts semi-structurés ont permis de recueillir les plantes les plus utilisées. L’indice de fidélité renseigne sur la convergence des usages quant à l’emploi des plantes comme bâtonnets frotte-dents comparé aux autres pratiques cosmétiques répertoriées. L’étude de la composition phytochimique des tiges a ciblé huit classes chimiques : stéroïdes, terpénoïdes, tanins, saponines, anthocyanines, leucoanthocyanidines, coumarines, émodines. Les tanins et les saponines sont très fréquents ; les terpénoïdes et les leucoanthocyanines presque inexistants. Un dosage des flavonoïdes, alcaloïdes et polyphénols, réalisé chez des extraits aqueux, a ensuite été effectué sur 12 plantes (huit familles). Les grandes teneurs en polyphénols et alcaloïdes sont mesurées chez Anogeissus leiocarpus, et la meilleure en flavonoïdes chez Commiphora africana.
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Tahiri, Annick, Augustin Amissa Adima, Anoh Félix Adje, and Nadine Amusant. "Effet pesticide et screening des extraits de Azadirachta indica (A.) Juss. sur le termite Macrotermes bellicosus Rambur." BOIS & FORETS DES TROPIQUES 310, no. 310 (December 1, 2011): 79. http://dx.doi.org/10.19182/bft2011.310.a20461.

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Pour préconiser l'application en champ d'une plante naturelle à propriété insecticide comme alternative à la lutte chimique contre les termites ravageurs, d'importants prérequis s'imposent sur son efficacité. La toxicité, la dose létale, le mode d'action, la persistance d'efficacité et la composition chimique des extraits totaux aqueux, alcoolique et hexanique des feuilles et des graines du neem, Azadirachta indica, ont été examinés sur l'espèce de termite ravageur Macrotermes bellicosus. La toxicité par contact des extraits est élevée sur le termite et provoque la mortalité totale des populations testées. La persistance d'efficacité des extraits est de 2,4 à 4,2 jours. Les extraits aqueux et hexanique sont les plus toxiques (DL50 de 0,422 ± 0,018 à 4,466 ± 0,162 mg/l). Le contact et l'inhalation sont les deux voies essentielles à leur efficacité. L'extrait aqueux de graines, le plus actif, est de plus capable de se transmettre dans la colonie lors des tâches sociales. Mais il n'agit pas par ingestion et il semble anti-appétant vis-àvis du termite. Il contient des composés phénoliques (tanins et flavonoïdes) et des saponines. L'extrait hexanique de graines est de type oléique, renferme 11 acides gras et contient des terpénoïdes, des flavonoïdes et des saponines. (Résumé d'auteur)
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Sauvaire, Y., G. Ribes, JC Baccou, and MM Loubatières-Mariani. "Effet des saponines stéroïdiques de fenugrec sur l'hypercholestérolémie du chien diabétique." Reproduction Nutrition Développement 30, no. 1 (1990): 129. http://dx.doi.org/10.1051/rnd:19900123.

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Dissertations / Theses on the topic "Saponines"

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Voutquenne-Nazabadioko, Laurence. "Saponines et activite hemolytique : saponines et glycosides de cinq especes de sapindaceae." Reims, 1997. http://www.theses.fr/1997REIMP208.

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Nazabadioko, Serge. "Synthese d'oligosaccharides pour l'hemisynthese de saponines." Reims, 1996. http://www.theses.fr/1996REIMP202.

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Dijoux, Marie-Geneviève. "Saponines et flavonoides de beta vulgaris l." Reims, 1993. http://www.theses.fr/1993REIMP206.

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Benkhaled, Mohammed. "Determination de structures de saponines de medicago." Reims, 1992. http://www.theses.fr/1992REIMP206.

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Lamidi, Maroufath. "Nauclea diderrichii : etudes phytochimique et pharmacologique." Aix-Marseille 1, 1996. http://www.theses.fr/1996AIX11071.

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L'etude phytochimique de nauclea diderrichii (de wild) merr. Nous a permis d'isoler et de determiner la structure de onze saponosides (glycosides de l'acide quinovique), dont cinq sont des composes decrits pour la premiere fois. Deux glucoalcaloides dont un nouveau, un glycoside terpenique de structure originale et un secoiridoide ont egalement ete identifies. L'activite pharmacologique des extraits de saponosides, d'alcaloides, ainsi que des molecules isolees, a ete testee sur: candida albicans, trichomonas vaginalis, leishmania infantum et plasmodium falciparum. Les alcaloides totaux ont l'activite leischmanicide et antimalarique la plus elevee in vitro. Les saponosides ont egalement une activite antimalarique interessante. Le pretraitement des hematies parasitees par plasmodium falciparum par une solution de saponosides permet de majorer l'activite des alcaloides de maniere significative
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Timite, Gaoussou. "Isolement et caractérisation des saponosides de plantes de la famille des Alliaceae, Caryophyllaceae et Polygalaceae, et évaluation de leurs activités cytotoxiques sur cellules tumorales." Thesis, Dijon, 2012. http://www.theses.fr/2012DIJOPE03/document.

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Cette thèse s’inscrit dans le cadre de la thématique du laboratoire de Pharmacognosie de l’UFR Pharmacie, au sein de l’Université de Bourgogne. Elle vise essentiellement la recherche de molécules d’origine végétale issue de la biodiversité tropicale dotées d’une activité antitumorale, dont principalement les saponines. Ce sont des glycosides triterpéniques ou stéroïdiques connus pour leurs nombreuses propriétés pharmacologiques. L’étude de 6 espèces végétales appartenant à 3 familles à savoir Acanthophyllum elatius, A. lilacinum, A. sordidum et Arenaria montana (Caryophyllaceae), Securidaca welwitschii (Polygalaceae) et Allium schoenoprasum (Alliaceae) a conduit à l’isolement et à la caractérisation de 24 glycosides naturels. Il s’agit de 13 saponines triterpéniques parmi lesquelles 10 sont de structure nouvelle ainsi que 11 saponines stéroïdiques dont 7 nouvelles. Les structures ont été élucidées principalement par l’utilisation de la RMN 2D ainsi que la spectrométrie de masse. 10 des 24 molécules isolées ont été testées en vue d’évaluer leurs activités cytotoxiques sur deux lignées cellulaires cancéreuses coliques (HT-29 et HCT 116). Nos résultats montrent que 9 d’entre elles possèdent une activité cytotoxique significative. Des relations structure/activité ont été ainsi proposées
This thesis was realized in the laboratory of Pharmacognosy, in the Pharmacy section of the Bourgogne University. The main theme of this laboratory is the research of natural saponins from the tropical biodiversity, with antitumoral activities. These molecules are triterpenic or steroidic glycosides, well known for their various pharmacological activities. The study of 6 species belonging to 3 different families : Acanthophyllum elatius, A. lilacinum, A. sordidum and Arenaria montana (Caryophyllaceae), Securidaca welwitschii (Polygalaceae) and Allium schoenoprasum (Alliaceae), led to the isolation and characterization of 24 natural glycosides. Among them, 13 were triterpenic saponins with 10 new structures and 11 were steroidic saponins with 7 new structures. The spectral analysis was achieved using mainly 2D NMR and mass spectrometry. The cytotoxic activities of 10 isolated compounds were evaluated on 2 strains of human colon cancer cells (HT-29 et HCT 116) and 9 were active ones. Structure/activity relationships were also proposed
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Paphassarang, Somboun. "Contribution à l'étude botanique et phytochimique de Polyscias scutellaria (Burm. F. ) Fosb. (araliaceae)." Lyon 1, 1987. http://www.theses.fr/1987LYO1W256.

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Fulcheri, Corinne. "Contribution à l'amélioration des conditions de culture des cellules de Saponaria officinalis l. Et des racines des Gypsophila paniculata L. Pour la production de saponines triterpéniques." Toulouse, INPT, 1998. http://www.theses.fr/1998INPT008A.

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Les cellules de saponaria officinalis et les racines de gypsophila paniculata (caryophyllacees) cultivees in vitro constituent des modeles de production de saponines triterpeniques avec une bonne reproductibilite dans le temps. La mise au point d'une methode de purification par des fractionnements chromatographiques successifs des saponines extraites des cellules de saponaria officinalis a contribue a obtenir une faible quantite d'un melange saponosidique complexe. Les milieux de culture in vitro mh2 et mh3, dont la composition minerale a ete basee sur les besoins hydromineraux des plantes entieres cultivees en hors sol, ont permis d'augmenter la production de biomasse et l'accumulation des saponines par rapport aux milieux de base msa et b5, respectivement de 350 a 700 g/l et de 2. 5 a 4. 4 mg/g de matiere fraiche/l pour les cellules de saponaria officinalis, et de 350 a 750 g/l et de 10 a 30 mg/g de matiere fraiche/l pour les racines de gypsophila paniculata. L'epuisement des elements mineraux des milieux a ete suivi au cours d'un cycle de culture des cellules de saponaria officinalis et des racines de gypsophila paniculata, en prelevant quotidiennement un volume minimal de milieu pour l'analyse minerale, sans ouvrir les fioles de culture. Cette etude a montre une composition minerale des milieux mh parfaitement adaptee aux cultures in vitro. Inversement, les cultures sur les milieux de base ont revele la presence de facteurs limitants (phosphate et cuivre), un effet antagoniste de l'ammonium sur l'absorption du potassium et une absorption passive des ions sodium et chlore, consideres comme non indispensables.
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Zebiri, Ilhem. "Etude phytochimique et biologique de cinq espèces de la flore péruvienne. Evaluation de leurs propriétés antileishmanienne et cytotoxique." Thesis, Reims, 2015. http://www.theses.fr/2015REIMS043/document.

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Ce travail présente l’étude phytochimique de cinq plantes péruviennes, Myrsine latifolia, M. congesta et M. sessiliflora (Primulaceae ex Myrsinaceae), Poraqueiba sericea (Icacinaceae) et Dendrobangia boliviana (Cardiopteridaceae ex Icacinaceae). L’étude des trois Myrsine nous a permis d’isoler onze composés déjà connus dans la littérature qui ont été testés pour leurs activités antileishmanienne (criblage sur Leishmania infantum promastigotes en luminescence) et cytotoxique (test in vitro sur des fibroblastes). Les résultats étaient négatifs pour les deux activités. A partir des tiges de Poraqueiba sericea nous avons pu isoler onze composés dont six triterpènes et trois saponines monodesmosides décrits pour la première fois dans cette famille de plante et deux sécoiridoïdes. Différentes activités biologiques ont été évaluées pour ces molécules : activités leishmanicide, cytotoxique et anti-élastase. Seuls les derniers tests ont révélés des activités pour deux tripterpénoïdes et pour le secologanoside. A partir de Dendrobangia boliviana quatorze saponines ont pu être isolées dont douze sont de nouveaux glycosides des acides serjanique ou phytolaccinique. L’analyse en LC-RMN a permis d’identifier cinq autres saponines de structures nouvelles. Ces composés ont été testés pour leurs activités biologiques et n’ont démontré aucune activité hémolytique et trois d’entre eux ont révélé une cytoxicité sur les fibroblastes. Les tests antileishmaniens n’ont révélé aucune activité. En bioautographie (HPTLC) ces saponines présentent un potentiel intéressant pour différentes activités biologiques (tyrosinase, α et β-glucosidases et acétylcholinestérase)
This work presents the phytochemical study of five Peruvian plants, Myrsine latifolia, M. congesta and M. sessiliflora (Primulaceae ex Myrsinaceae), Poraqueiba sericea (Icacinaceae) and Dendrobangia boliviana (Cardiopteridaceae ex Icacinaceae). The study of the three Myrsine enabled us to isolate eleven compounds already known in the literature which were tested for their antileishmanial (screening of Leishmania promastigotes luminescence) and cytotoxic activities (in vitro test on fibroblasts). The results were negative for both activities. From the stems of Poraqueiba sericea we were able to isolate eleven compounds including six triterpenes, three monodesmosides saponins described for the first time in this plant family and two secoiridoides. Various biological activities have been evaluated for these molecules: leishmanicidal, cytotoxic and anti-elastase activities. Only the last testing has suggested activities for two tripterpénoïdes and the secologanoside. From Dendrobangia boliviana fourteen saponins have been isolated including twelve novel glycosides of the serjanique or phytolaccinique acids. The analysis by LC-NMR allowed us to identify five other saponins with new structures. These compounds were tested for their biological activities and showed no hemolytic activity and three of them showed a cytotoxicity on fibroblasts. The antileishmanial test showed no activity. In bioautography (HPTLC) these saponins showed an interesting potential for different biological activities (tyrosinase, α and β-glucosidase and acetylcholinesterase)
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Delay, Corinne. "Isolement, caractérisation et identification de saponines hémolytiques de gypsophila paniculata." Montpellier 1, 1998. http://www.theses.fr/1998MON13526.

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Books on the topic "Saponines"

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1953-, Marston A., ed. Saponins. Cambridge: Cambridge University Press, 1995.

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Waller, George R., and Kazuo Yamasaki, eds. Saponins Used in Food and Agriculture. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0413-5.

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R, Waller George, Yamasaki Kazuo, American Chemical Society Meeting, and American Chemical Society Symposium on Saponins: Chemistry and Biological Activity (1995 : Chicago, Ill.), eds. Saponins used in food and agriculture. New York: Plenum Press, 1996.

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Koh, Rani. Saponins: Properties, applications, and health benefits. Hauppauge, N.Y: Nova Science Publishers, 2011.

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Oleszek, W., and A. Marston. Saponins in food, feedstuffs, and medicinal plants. Dordrecht: Springer, 2011.

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Oleszek, Wieslaw, and Andrew Marston, eds. Saponins in Food, Feedstuffs and Medicinal Plants. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-015-9339-7.

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Waller, George R., and Kazuo Yamasaki, eds. Saponins Used in Traditional and Modern Medicine. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-1367-8.

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R, Waller George, Yamasaki Kazuo, and American Chemical Society Symposium on Saponins: Chemistry and Biological Activity (1995 : Chicago, Ill.), eds. Saponins used in traditional and modern medicine. New York: Plenum Press, 1996.

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W, Oleszek, and Marston A. 1953-, eds. Saponins in food, feedstuffs and medicinal plants. Dordrecht: Kluwer Academic Publishers, 2000.

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Bócsa, Iván. Nemesítés a lucerna antinutritív anyagai ellen: Akadémiai székfoglaló, 1991. szeptember 10. Budapest: Akadémiai Kiadó, 1994.

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Book chapters on the topic "Saponines"

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Pengelly, Andrew. "Triterpenoids and saponins." In The constituents of medicinal plants, 95–111. 3rd ed. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789243079.0006.

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Abstract This chapter focuses on the various classes of triterpenoids (free triterpenes, triterpenoid saponins, steroidal saponins, cardiac glycosides, phytosterols, phytoecdysteroids, curcurbitacins and quassinoids), which occur in the free state within plants or as aglycones of glycosides. Information on the chemical structures and pharmacological actions of these triterpenoids and saponins are also presented.
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Makkar, Harinder P. S., P. Siddhuraju, and Klaus Becker. "Saponins." In Plant Secondary Metabolites, 93–100. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-425-4_16.

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Bashir, Usma, Nafia Qadir, and Idrees Ahmad Wani. "Saponins." In Handbook of Plant and Animal Toxins in Food, 177–90. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003178446-9.

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Bährle-Rapp, Marina. "Saponine." In Springer Lexikon Kosmetik und Körperpflege, 490. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_9116.

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Bährle-Rapp, Marina. "Saponins." In Springer Lexikon Kosmetik und Körperpflege, 490. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_9117.

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Oakenfull, David, and Gurcharn S. Sidhu. "Saponins." In Toxicants of Plant Origin, 97–142. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003418276-4.

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Mahato, S. B., and S. Garai. "Triterpenoid Saponins." In Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, 1–196. Vienna: Springer Vienna, 1998. http://dx.doi.org/10.1007/978-3-7091-6496-9_1.

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Sahu, N. P., S. Banerjee, N. B. Mondal, and D. Mandal. "Steroidal Saponins." In Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, 45–141. Vienna: Springer Vienna, 2008. http://dx.doi.org/10.1007/978-3-211-74019-4_2.

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Massiot, Georges, Marie-Geneviève Dijoux, and Catherine Lavaud. "Saponins and Artifacts." In Advances in Experimental Medicine and Biology, 183–92. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0413-5_15.

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Bomford, R. "Saponins as Immunoadjuvants." In Immunological Adjuvants and Vaccines, 43–46. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-0283-5_6.

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Conference papers on the topic "Saponines"

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Sidorova, Yulia, Nikita Petrov, and Irina Perova. "Amaranth saponines: Identification and characterization." In INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “CURRENT ISSUES OF BIOLOGY, BREEDING, TECHNOLOGY AND PROCESSING OF AGRICULTURAL CROPS” (CIBTA2022) (To the 110th anniversary of V.S. Pustovoit All-Russian Research Institute of Oil Crops). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0140402.

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Sukhenko, Liudmila, Elsayed Zeitar, Anna Fedotova, and Mikhail Egorov. "Prospects of naked licorice cultivation in the caspian region for the creation of foam licorice baths (based on the drug glytsrfit)." In Innovations in Medical Science and Education. Dela Press Publishing House, 2022. http://dx.doi.org/10.56199/dpcsms.bjse2063.

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The prospects of cultivation of naked licorice in the territory of the Caspian region and the possibility of using extractive saponin-containing foaming components of licorice root to create foam licorice baths with foam content stability were studied. The latitude, longitude, and height of licorice root collection sites with row furrows are presented only in rows. A new approach to preserving the hydrophilic-lipophilic balance in a licorice bath is proposed by embedding colloidal surfactants into the micelles of licorice root saponins, which increases the stability of licorice foam in the bath. The data of the critical concentration of micelle formation are presented. The possibility of restoring the stocks of licorice naked during its cultivation and harvesting by the row method is shown, and methods for preserving the solubilizing ability of foam licorice baths under conditions of preserving licorice foam micelles in the presence of some surfactants are disclosed.
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Le Bot, M., D. Guilet, and S. Boisard. "Combination of two spectrophotometric methods for total quantification of steroidal and triterpenoid saponins contents in saponin plants mixtures." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759031.

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Authi, K. S., B. J. Evenden, and N. Crawford. "ACTION OF GTPγS [GUANOSINE 5∲-0-(3-THIOPHOSPHATE)] ON SAPONIN-PERMEABILISED PLATELETS: INVOLVEMENT OF 'G' PROTEINS IN PLATELET ACTIVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644514.

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Certain ligand-receptor interactions at cell surfaces lead to the phospholipase-C (PLC) hydrolysis of phosphatidyl inositol (4.5) bisphosphate (PIP2). The products serve as intracellular second messengers, e.g. inositol (1.4.5) trisphosphate (IP3) releases Ca2+ from intracellular stores and diacylglycerol activates protein kinase-C. From studies using GTP and analogues (e.g. GTPγS) there is evidence of a key role for a guanine nucleotide binding protein(s) as a link between receptors and PIP2 hydrolysis. We report the actions of GTPγS on washed human platelets permeabilised with saponin (12-14 μg/ml) to allow penetration of low MWt polar substances. The responses to GTPγS are dose dependent (range 9-60 μM) and at 60 μM the agent induces shape change, aggregation and the secretion of 50% of previously incorporated [14C]-5HT. No effect of GTPγS is seen with intact cells. Shape change occurs 25-30 sec after GTPγS; aggregation and secretion is complete after 3 min. When GTP was used (up to 135 μM) with similarly permeabilised platelets no responses were initiated. Phosphatidylinositol turnover was monitored using 32P-labelling before permeabilisation. The addition of 90 μM GTPγS resulted in a 143 ± 23% (n=4) increase in 32P-phosphatidic acid (PA) with respect to the basal levels of “saponised control” cells. These findings suggest that GTPγS stimulates PLC activity through a ‘G’ protein interaction. The GDP analogue (GDPβS) produced no activation responses in saponised platelets but inhibited responses induced by GTPγS in a dose dependent manner (0-480 μM, max inhibition 480 μM). At 960 μM, GDPβS totally inhibited aggregation and secretion initiated by low doses of thrombin (0.1 U/ml) and collagen (1 μg/ml). Identical inhibition by GDPβS of thrombin and collagen-induced activation of intact platelets was observed indicating membrane penetration of this analogue. Shape change effects were not inhibited by GDPSS. The inhibitory effects of GDPSS towards thrombin and collagen induced secretion could be progressively overcome at higher doses of thrombin (0.2 U/ml - 2 U/ml) and collagen (5 μg/ml - 60 μg/ml) suggesting that at higher concentrations these agonists may exert effects through 'G' protein-independent mechanisms.
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Tian, Jing, Sen Zhao, Bin Zhai, and Longquan Xu. "Biotransformation of Group B Soybean Saponins." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5515692.

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Segaran, Abirame, and Lee Suan Chua. "Saponins Rich Fractions From Eurycoma longifolia Extract." In Third International Conference on Separation Technology 2020 (ICoST 2020). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/aer.k.201229.008.

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Oliveira, Diogo Willian Santos, Adriana Kuhn, Alexandra Aparecida do Amaral, and Letycia Lopes Ricardo. "Saponinas: um composto bioativo muito importante para indústria." In IV Congresso Online Nacional de Química. Congresse.me, 2022. http://dx.doi.org/10.54265/lrom7439.

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Nechaeva, M. V., and I. F. Golovatskaya. "The effect of sodium selenite on the secondary metabolism of cell culture Lychnis chalcedonica in vitro." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.181.

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We studied the effect of sodium selenite (Se) on the secondary metabolism of Lychnis chalcedonica L. cell culture in vitro. It was found that low concentrations of Se reduce the flavonoid content, but do not change the content of saponins.
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Som, Ayub Md, Norizan Ahmat, Hairul Amani Abdul Hamid, Siti Raihanah Abdul Rahman, Nurul Amirrah Rahimudin, Nur Amira Zainidi, and Adilah Amirah Ayub. "Phytochemical Screening and Antioxidant Activity of <i>Hylocereus undatus</i> Foliage: Effects of Using Different Drying and Assays Methods." In 5th International Conference on Global Sustainability and Chemical Engineering 2021 (ICGSCE2021). Switzerland: Trans Tech Publications Ltd, 2023. http://dx.doi.org/10.4028/p-m2r02u.

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Phytochemical screening was conducted on Hylocereusundatus foliage to determine the presence of alkaloids, flavonoids, tannins, and saponins using methanol and chloroform solvents via oven-dried and open air-dried methods. As for the antioxidant activity, powdered Hylocereusundatus foliage were extracted using both solvents through Ferric Reduction Antioxidant Power (FRAP) assay; and the findings were then compared to 2,2-Diphenyl-1-Ipicrylhydrazyl (DPPH) assay from previous studies. Results revealed that for both methods in phytochemical screening, flavonoids were present only in methanol extract; however, saponins were present in both extracts. No alkaloid and tannins were present in both extracts using both methods. Antioxidant activity results revealed that the methanol extract (59.05%) and chloroform extract (20.58%) using the FRAP assay were comparable to that of DPPH assay in which methanol extract (88.81%) and chloroform extract (38.30%) were obtained. It concludes that Hylocereusundatus has comparable phytochemical constituents and antioxidant activity based on the different drying and assay methods.
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Góis, Genival Vinícius De Andrade, and Maria Denise Leite Ferreira. "TRIBULUS TERRESTRIS E A MEDICINA TRADICIONAL." In III Congresso Brasileiro de Ciências Farmacêuticas On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbracif/12.

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Introdução: A Tribulus terrestris, popularmente conhecida como videira da punctura, abrolho terrestre, rabo-de-calango, tribulo, tribulus e cabeça-de-touro, é uma erva daninha da família Zygophyllaceae com propriedades medicinais e fama afrodisíaca. Planta nativa e frequente na Europa e Sul da Ásia, atualmente, pode ser encontrada em diferentes regiões do mundo, sendo considerada uma planta invasora. Objetivo: Revisar sobre informações existentes a respeito da Tribulus terrestris e seu uso medicinal, levando em consideração a sua composição química, assim como sua utilização na medicina tradicional. Material e métodos: Trata-se de uma pesquisa efetuada por meio de revisão bibliográfica de artigos científicos encontrados nas bases de dados da Scientific Electronic Library Online (SCIELO) e Medical Literature Analysis and Retrieval System Online (MEDILINE), o critério de inclusão utilizado foi a compatibilidade com o tema, foram utilizados artigos em português e inglês produzidos nos últimos cinco anos. Resultados: Na composição da tribulus são encontradas substâncias como saponinas, flavonóides, glicosídeos, alcalóides e taninos, sendo as saponinas as substâncias mais importantes e estudadas nesta planta por suas propriedades. As saponinas, em específico a protodioscina e protogracilina presentes na planta, são responsáveis pela fama afrodisíaca. A tribulus apresenta atividade diurética devido a sua concentração de nitrato e óleo essencial presentes em seus frutos e sementes, em animais apresenta também várias outras atividades farmacológicas como ativada antiurolítica e imunomoduladora, mas existe a carência de amplos estudos dessas atividades farmacológicas em humanos. Tradicionalmente, esta planta é historicamente utilizada na medicina tradicional da China, Ayuveda e Unani para tratar disfunção erétil, fígado deprimido, utilizada como cardiotônico, diurético entre outras atividades medicinais atribuídas a planta. Conclusão: Assim sendo, o uso da Tribulus terrestris é antigo na sociedade e está presente em diversas medicinas tradicionais. Famosa por seu efeito afrodisíaco, mas existe a possibilidade da tribulus contribuir para medicina moderna com sua atividade farmacológica.
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Reports on the topic "Saponines"

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Guven, N., D. J. Panfil, and L. L. Carney. Evaluation of saponite and saponite/sepiolite fluids for geothermal drilling. Office of Scientific and Technical Information (OSTI), February 1991. http://dx.doi.org/10.2172/5908401.

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Kerem, Zohar, Yael Vodovotz, David Bonfil, Steven J. Schwartz, and Mark Failla. Do Saponins Present in Model Systems and Legume Bread Modulate Cholesterol Absorption in vitro and in vivo? United States Department of Agriculture, August 2011. http://dx.doi.org/10.32747/2011.7592656.bard.

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No abstract. The overall general goal of the research project was to provide evidence for the beneficial biological activity of saponins from edible legumes, and to incorporate them into bread hat will become a functional food. Its functionality is in its ability to attenuate the absorption of dietary lipids and cholesterol.
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Popov, Georgi, Aleksander Shkondrov, Magdalena Kondeva-Burdina, Vasil Manov, and Irena Krasteva. Effect of a Purified Saponins Mixture from Astragalus glycyphylloides on Rat Hepatocytes. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, May 2021. http://dx.doi.org/10.7546/crabs.2021.05.09.

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Duran, E., O. Mayorga, A. Calvo, D. Parra, and L. Mestra. Evaluación del contenido de metabolitos secundarios en recursos forrajeros del trópico colombiano mediante espectroscopia de infrarrojo. Corporación colombiana de investigación agropecuaria - AGROSAVIA, 2019. http://dx.doi.org/10.21930/agrosavia.poster.2019.21.

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La producción ganadera en Colombia se basa en el pastoreo y los recursos forrajeros provienen principalmente de gramíneas (GF), leguminosas (LF) y/o arbóreas (AF), los cuales pueden contener metabolitos secundarios como taninos, saponinas, compuestos fenólicos y alcaloides, y que dependiendo de su concentración pueden causar efectos negativos a nivel fisiológico y/o nutricional o modular en forma positiva el ecosistema ruminal de los animales [1]. Definir una metodología única para cada uno de los compuestos y los tipos de forrajes en el marco de la biodiversidad colombiana genera un reto para explorar la potencialidad de los recursos forrajeros de los sistemas de producción colombiana. La espectroscopia de infrarrojo cercano (NIRS) está siendo usada para determinar la composición de macro-componentes de los forrajes [2] y podría ser utilizada para predecir la concentración de metabolitos secundarios.
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Du, Yuqing, Huimin Lu, Yaoqing Sun, Weian Yuan, Renyan Huang, Xuhong Wang, Guobin Liu, and Weijing Fan. Systematic review and meta-analysis of the efficacy and safety of Panax notoginseng saponins in the prevention of lower-extremity deep venous thrombosis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2023. http://dx.doi.org/10.37766/inplasy2023.3.0032.

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Review question / Objective: P: Participants must be individuals diagnosed with LEDVT. I: Panax Notoginseng Saponions (PNS) alone or PNS combined with routine western medicine treatment; C: Western medicine. O: The Incidence of LEDVT. Condition being studied: The lower-extremity deep vein thrombosis (LEDVT) is a condition that is common in postoperative and intensive care patients. It is caused by impaired venous reflux, endothelial dysfunction and ahypercoagulability. Eligibility criteria: All randomized controlled trials (RCTs) exploring the clinical outcomes of PNS alone or PNS combined with western medicine versus western medicine with LEDVTwere includedAll randomized controlled trials (RCTs) exploring the clinical outcomes of Zishen Yutai Pill plus western medicine versus western medicine with TM in woman were included.
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Li, Hui, Na Li, and Chongwen Ren. Reliability of the evidence to guide decision-making in Panax notoginseng saponins for acute ischemic stroke: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0108.

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Guan, Peiyu, Dingkun Gui, and Youhua Xu. Evaluation on the efficacy and safety of Panax notoginseng saponins in the treatment of stroke among elderly people - A systematic review and meta-analysis of 206 randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2023. http://dx.doi.org/10.37766/inplasy2023.3.0042.

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Review question / Objective: Population: The symptoms of the population were in line with the relevant diagnostic criteria for stroke both at home and abroad, and were confirmed as ischemic stroke by medical imaging tests such as MRI or CT.The subject groups were older adults with an average age of over 60, regardless of gender or race. Intervention: Intervention involves single use of PNS or combined use of PNS and WM or PNS and Treatment as usual (TAU). Comparator: All the patients in the controlled group underwent conventional routine treatment to improve their cerebral blood supply and drug treatment. Outcomes: Measurement for the outcomes should be clearly defined and includes at least one of the below items: neurological deficit score, the clinical response rate and assessment of Activities of daily living (ADLs). Study design: All the included studies were RCTs or clinical controlled trials. The study design adopted RCT.
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