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Journal articles on the topic 'Saw palmetto'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Carrington, M. E., P. D. Roberts, N. V. R. R. Urs, R. J. McGovern, T. E. Seijo, and J. J. Mullahey. "Premature Fruit Drop in Saw Palmettos Caused by Colletotrichum gloeosporioides." Plant Disease 85, no. 2 (2001): 122–25. http://dx.doi.org/10.1094/pdis.2001.85.2.122.

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Saw palmetto (Serenoa repens) is a palm species that grows naturally in the southeastern coastal plain of the United States and is most abundant in Florida. Extracts from saw palmetto fruit are sold worldwide in pharmaceutical and dietary supplements in a market valued at $2 billion per year. Lesions on blossoms and fruit and premature fruit drop were first observed in 1996. In 1997, premature fruit drop resulted in 100% loss of fruit in saw palmetto in central and south Florida. In 1998, fruit loss was 8 to 59%. A fungus was consistently isolated from diseased saw palmetto spadices and fruit

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2

Ding, Hong, Jinglian Shen, Yang Yang, and Yuqin Che. "Saw Palmetto Extract Inhibits Metastasis and Antiangiogenesis through STAT3 Signal Pathway in Glioma Cell." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/926946.

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Signal transducer and activator of transcription factor 3 (STAT3) plays an important role in the proliferation and angiogenesis in human glioma. Previous research indicated that saw palmetto extract markedly inhibited the proliferation of human glioma cells through STAT3 signal pathway. But its effect on tumor metastasis and antiangiogenesis is not clear. This study is to further clear the impact of saw palmetto extract on glioma cell metastasis, antiangiogenesis, and its mechanism. TUNEL assay indicated that the apoptotic cells in the saw palmetto treated group are higher than that in the con

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3

Kruthi, H. B., H. Shreya, Ch Mahendra, R. R. Siva Kiran, and Archna. "Removal of Methylene Blue Dye Using Saw Palmetto Fruit (Serenoa repens) Waste." Asian Journal of Chemistry 31, no. 9 (2019): 1919–25. http://dx.doi.org/10.14233/ajchem.2019.22016.

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The feasibility of saw palmetto fruit (Serenoa repens) waste as a low-cost bio-sorbent for treating methylene blue dye from synthetic textile effluent was evaluated. Two different types viz., untreated and alkaline treated saw palmetto fruit waste was tested to immobilize methylene blue dye from the synthetic effluent solution. Out of these two, the only alkaline treated saw palmetto fruit waste was found suitable for the removal of methylene blue from aqueous streams. With the untreated saw palmetto fruit waste, the sorption of dye increased with time and after reaching equilibrium, back diff

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4

Batista, Rosangela. "Saw Palmetto Flowers." Wallace Stevens Journal 47, no. 2 (2023): 249. http://dx.doi.org/10.1353/wsj.2023.a910926.

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5

Wang, Mei, Bharathi Avula, Yan-Hong Wang, Jianping Zhao, Jon F. Parcher, and Ikhlas A. Khan. "Fatty Acid Analysis of Saw Palmetto (Serenoa repens) and Pygeum (Prunus africana) in Dietary Supplements by Gas Chromatography/Mass Spectrometry in the Selected Ion Monitoring Mode." Journal of AOAC INTERNATIONAL 96, no. 3 (2013): 560–66. http://dx.doi.org/10.5740/jaoacint.12-284.

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Abstract A GC/selected ion monitoring mode-MS (GC/SIM-MS) method was developed to chemically distinguish saw palmetto and pygeum in dietary supplements. A sample set including authenticated plant samples, commercial plant extracts, a National Institute of Standards and Technology standard reference material extract, and commercial dietary supplements purported to contain either saw palmetto, pygeum, or both was investigated. Fatty acid methyl esters (FAMEs) were analyzed by GC/SIM-MS. The ability to selectively monitor each solute allowed accurate quantitation of all detected FAMEs, even those

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6

Agbabiaka, Taofikat B., Max H. Pittler, Barbara Wider, and Edzard Ernst. "Serenoa repens (Saw Palmetto)." Drug Safety 32, no. 8 (2009): 637–47. http://dx.doi.org/10.2165/00002018-200932080-00003.

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7

Jibrin, Ismaila, Ayodele Erinle, Abdulfattah Saidi, and Zakari Y. Aliyu. "Saw Palmetto-induced Pancreatitis." Southern Medical Journal 99, no. 6 (2006): 611–12. http://dx.doi.org/10.1097/01.smj.0000215642.76198.44.

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8

Gaweł-Bęben, Katarzyna, Wirginia Kukula-Koch, Dominik Szwajgier, et al. "Synergism of Specific Maca Phenotypes (Lepidium peruvianum) in Combination with Saw Palmetto (Serenoa repens) Extract for Chemoprevention of Prostate Cancer as Determined in In Vitro Cytotoxicity Assays on Human Epithelial and Prostate Cancer Cells." Molecules 29, no. 23 (2024): 5632. http://dx.doi.org/10.3390/molecules29235632.

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Selected phenotypes of dried maca (Lepidium peruvianum) hypocotyls and supercritical CO2 extract (USPlus®) of saw palmetto (Serenoa repens) were used to determine their targeted, cytotoxic action in prostate cancer cells. Fingerprinting by HPLC-MS and PCA analysis showed compositional differences in glucosinolates, amides, macamides, and other alkaloids, which varied based on the color and the size of hypocotyls. These phytochemical differences translated into a higher antioxidant potential of red maca than black maca samples. The greatest COX-2 inhibition was demonstrated with a combination o

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9

Barnes, Joanne. "Charms & Harms: Saw palmetto." Journal of Primary Health Care 1, no. 4 (2009): 323. http://dx.doi.org/10.1071/hc09323.

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SUMMARY MESSAGE: There is no robust evidence that saw palmetto fruit extract is effective in the treatment of benign prostatic hyperplasia. Evidence indicates that it is a safe product (at current doses) but with questionable efficacy. As with all herbal medicines, saw palmetto products differ in their pharmaceutical quality, and the implications of this should be considered.

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10

Abdul Majeed, Zaid M., and Mohammed Q. Al-Atrakji. "Possible Protective Effects of Saw Palmetto Extract in Indomethacin Treated Rats." Journal of the Faculty of Medicine Baghdad 67, no. 1 (2025): 97–103. https://doi.org/10.32007/jfacmedbaghdad2474.

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Background: Indomethacin is a widely used nonsteroidal anti-inflammatory drug for treating pain and fever. It is coupled with oxidative stress and an inflammatory response, which accounts for several detrimental effects on the body’s organs. Objectives: This study aimed to assess the potential of using SSaw palmetto extract to counteract the oxidative stress and inflammatory response resulting from Indomethacin treatment in rat models. Methods: The study involved 20 male albino rats, arbitrarily sorted into four groups of 5 animals each group. Group 1 (control group) was neither induced nor tr

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11

Mazin Abdulridha Ateyah, Manal Khalid Abdulridha, and Munaim Jumaa Alkabee. "Effects of Saw Palmetto Therapy on some Inflammatory Biomarkers in a Sample of Iraqi Male with Symptomatic Benign Prostatic Hyperplasia." Al Mustansiriyah Journal of Pharmaceutical Sciences 21, no. 1 (2022): 1–9. http://dx.doi.org/10.32947/ajps.v21i1.774.

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Background Saw palmetto contains powerful anti-inflammatory components commonly used in Benign prostatic hyperplasia (BPH) patients with symptoms. The current study was designed to assess the effectiveness of saw palmetto alone or supplementation  therapy with tamsulosin via measurement of some inflammatory biomarker in male with lower urinary tract symptoms (LUTS) consistent with (BPH). Methods The present study is an interventional prospective randomized enrolled newly diagnosed patients with moderate to severe symptomatic BPH. The eligible 60 patients were allocated into (

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12

Shiver, Barry D., Steven A. Knowe, M. Boyd Edwards, and William N. Kline. "Comparison of Herbicide Treatments for Controlling Common Coastal Plain Flatwoods Species." Southern Journal of Applied Forestry 15, no. 4 (1991): 187–93. http://dx.doi.org/10.1093/sjaf/15.4.187.

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Abstract A study was conducted to identify optimum picloram-triclopyr combinations for use on the following flatwoods species: gallberry (Ilex glabra [L.] Gray), saw palmetto (Serenoa repens [Bartram] Small), vacciniums (Vaccinium spp.), waxmyrtle (Myrica cerifera L.), fetterbush (Lyonia lucida [Lam.] K. Koch), staggerbush (Lyonia ferruginea [Water] Nutall), and sweetbay (Magnolia virginiana L). More than 70% control of gallberry, saw palmetto, vacciniums, waxmyrtle, and sweetbay was obtained with 4.0 lb a.e./ac of triclopyr alone. At least 1.0 lb of picloram combined with 1.0 lb or more of tr

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13

Gong, Edward M., and Glenn S. Gerber. "Saw Palmetto and Benign Prostatic Hyperplasia." American Journal of Chinese Medicine 32, no. 03 (2004): 331–38. http://dx.doi.org/10.1142/s0192415x04001989.

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Benign prostatic hyperplasia (BPH) is a common health issue that affects 8% of all men at the age of 40, 60% of men in their 70s, and 90% of those greater than 80 years of age. One-fourth of these men will develop moderate to severe lower urinary tract symptoms that greatly affect their quality of life. Recent evidence suggests that the use of saw palmetto leads to improvements in urinary function for those suffering from BPH. The favorable comparison of saw palmetto with tamsulosin, a well-known first line agent in the treatment of urinary tract symptoms, demonstrates promise towards a benefi

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14

Evron, Evyatar, Margit Juhasz, Arash Babadjouni, and Natasha Atanaskova Mesinkovska. "Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia." Skin Appendage Disorders 6, no. 6 (2020): 329–37. http://dx.doi.org/10.1159/000509905.

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Saw palmetto (SP), a botanical extract with antiandrogenic properties, has gained commercial popularity for its purported benefits on hair regrowth. To summarize published evidence on the efficacy, safety, and tolerability of supplements containing SP in the treatment of alopecia, we conducted a PubMed, Google Scholar, and Cochrane database search using the following terms: (saw palmetto and hair loss), (saw palmetto and androgenetic alopecia), and (saw palmetto and natural supplement and alopecia). Five randomized clinical trials (RCTs) and 2 prospective cohort studies demonstrated positive e

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15

Carrington, Mary E., Monica Ozores-Hampton, and J. Jeffrey Mullahey. "368 Effects of Nitrogen Fertilization on Saw Palmetto (Serenoa repens)." HortScience 35, no. 3 (2000): 455F—456. http://dx.doi.org/10.21273/hortsci.35.3.455f.

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Saw palmetto (Serenoa repens), a palm species native to the Southeastern United States, is used in ornamental plantings and landscaping. From Mar. 1998 to Mar. 1999, we conducted an experiment to assess effects of different levels of nitrogen addition on three sizes of containerized saw palmettos in southwest Florida. Palmettos were in 26-L containers (plant height 30 to 50 cm, no above-ground rhizome), 38-L containers (plant height 50 to 80 cm, above-ground, prostrate rhizome), and 170-L containers (three erect above-ground rhizomes 1 to 2 m high). We applied granulated ammonium nitrate (34%

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16

Vanti, Giulia, Maria Camilla Bergonzi, and Anna Rita Bilia. "Development of Nanoliposomes Loaded with Carbon Dioxide Serenoa repens (Saw Palmetto) Extract." Journal of Nanoscience and Nanotechnology 21, no. 5 (2021): 2943–45. http://dx.doi.org/10.1166/jnn.2021.19045.

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Liposomes represent, among the nanocarriers, the most useful ones for dermatological use, and their composition, charge, size strongly influence their performance in topical drug delivery systems, with possible accumulation of the loaded drugs in the hair follicles. Recently, a saw palmetto carbon dioxide (CO2) extract has been reported useful for the treatment of hair loss because of the inhibition of 5α-reductase enzyme, responsible of the conversion of testosterone to the most potent androgen, the 5α-dihydrotestosterone. In this work, the formation of nano-sized liposomes and the encapsulat

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17

Carrington, Mary E., J. Jeffrey Mullahey, Gerard Krewer, Bob Boland, and James Affolter. "Saw Palmetto (Serenoa repens): An Emerging Forest Resource in the Southeastern United States." Southern Journal of Applied Forestry 24, no. 3 (2000): 129–34. http://dx.doi.org/10.1093/sjaf/24.3.129.

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Abstract Saw palmetto fruits collected from the wild are becoming a significant economic resource in Florida and south Georgia. The fruits are used to produce a drug for the treatment of benign prostatic hyperplasia (BPH). Here we introduce saw palmetto as an emerging resource for foresters and land managers, evaluate potential management practices, and discuss harvesting, processing and marketing aspects. Fruit production can be variable, affected by fruit disease, insect damage to flowers, depletion of plant carbohydrate reserves and drought. Controlled burning can enhance flowering and frui

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18

Reddy, Varshini, AdityaKumar Bubna, Mahalakshmi Veeraraghavan, and Sudha Rangarajan. "Saw palmetto extract: A dermatologist's perspective." Indian Journal of Drugs in Dermatology 3, no. 1 (2017): 11. http://dx.doi.org/10.4103/ijdd.ijdd_45_16.

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19

Bent, Stephen, Christopher Kane, Katsuto Shinohara, et al. "Saw Palmetto for Benign Prostatic Hyperplasia." New England Journal of Medicine 354, no. 6 (2006): 557–66. http://dx.doi.org/10.1056/nejmoa053085.

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20

TANZOLA, MELINDA. "Saw Palmetto Ineffective vs. Prostatic Hyperplasia." Internal Medicine News 39, no. 11 (2006): 40. http://dx.doi.org/10.1016/s1097-8690(06)73626-5.

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21

McVary, Kevin T. "Saw palmetto for benign prostatic hyperplasia." Current Urology Reports 7, no. 4 (2006): 251. http://dx.doi.org/10.1007/s11934-996-0002-4.

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22

McKinney, D. E. "Saw Palmetto for Benign Prostatic Hyperplasia." JAMA: The Journal of the American Medical Association 281, no. 18 (1999): 1699. http://dx.doi.org/10.1001/jama.281.18.1699.

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23

Roehrborn, C. G. "Saw Palmetto for Benign Prostatic Hyperplasia." Yearbook of Urology 2007 (January 2007): 99–100. http://dx.doi.org/10.1016/s0084-4071(08)70077-0.

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24

Rogers, George K. "Dioecy hotspots in Southeast Florida (U.S.A.), especially Saw Palmetto (Serenoa repens, Arecaceae) thickets." Journal of the Botanical Research Institute of Texas 18, no. 1 (2024): 149–62. http://dx.doi.org/10.17348/jbrit.v18.i1.1345.

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A survey of woody marshland hummocks, of Saw Palmetto (Serenoa repens, Arecaceae) thickets, and of additional Southeast Florida habitats revealed multiple sites with dioecy rates of 50–100%, especially in the Saw Palmetto thickets. These rates exceeded any encountered for woody species in a literature review globally or for Florida. A particularly notable feature of the thicket sites is extreme thick low-elevation palm frond canopy coverage, consistent with the historical perspective that a benefit of dioecy is sexual selection for seed quality where harsh ecological filters limit establishmen

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25

Beceren, Ayfer, Munise Efe, Merve Gurboga, and Kevser Cure. "Investigation of the Antiproliferative and Genotoxic Effects of Serenoa repens (W. Bartram) Small Extracts Available in the Market." Pharmedicine Journal 2, no. 2 (2025): 75–82. https://doi.org/10.62482/pmj.33.

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Introduction: Serenoa repens (W. Bartram) Small (Saw Palmetto), commonly referred to as the small palm, has been used in both traditional and modern medicine for centuries. Known for its diuretic, endocrinological, anabolic, and anti-inflammatory properties, Saw Palmetto is mostly used to treat benign prostatic hyperplasia (BPH). Known for its diuretic, endocrinological, anabolic, and anti-inflammatory properties, Saw Palmetto is mostly used to treat BPH. There has been a recent surge in interest in these products because herbal products are believed to be safer and have fewer side effects. Ph

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26

&NA;. "Saw palmetto does not improve BPH symptoms." Inpharma Weekly &NA;, no. 1525 (2006): 11. http://dx.doi.org/10.2165/00128413-200615250-00024.

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27

Pitman, W. D. "Evaluation of saw palmetto for biomass potential." Bioresource Technology 43, no. 2 (1993): 103–6. http://dx.doi.org/10.1016/0960-8524(93)90167-a.

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28

Wilt, TJ, A. Ishani, and G. Stark. "SAW PALMETTO EXTRACTS FOR BENIGN PROSTATIC HYPERPLASIA." Southern Medical Journal 92, no. 4 (1999): 433. http://dx.doi.org/10.1097/00007611-199904000-00021.

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29

Yeu, Elizabeth, and Richard Grostern. "Saw palmetto and intraoperative floppy-iris syndrome." Journal of Cataract & Refractive Surgery 33, no. 5 (2007): 927–28. http://dx.doi.org/10.1016/j.jcrs.2006.12.032.

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30

Villaverde, Nicole, Adriana Galvis, Adriana Marcano, Horacio A. Priestap, Bradley C. Bennett, and M. Alejandro Barbieri. "Saw palmetto ethanol extract inhibits adipocyte differentiation." Journal of Natural Medicines 67, no. 3 (2012): 619–25. http://dx.doi.org/10.1007/s11418-012-0723-2.

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31

Ismaila, Jibrin, Ayodele Erinle, and Zakari Aliyu. "Saw Palmetto–Induced Acute Hepatitis and Pancreatitis." Southern Medical Journal 98, Supplement (2005): S68. http://dx.doi.org/10.1097/00007611-200510001-00191.

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32

Jain, Sunjay, and Kilian Mellon. "Re: Saw Palmetto for Benign Prostatic Hyperplasia." European Urology 50, no. 3 (2006): 619. http://dx.doi.org/10.1016/j.eururo.2006.06.044.

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33

Dmytrenko, Oleksandra, Tetiana Lutsenko, Andrii Dmytrenko, and Olena Bespalova. "Assessment of Efficiency and Safety of Phytocomposition with Prostate-Protective Properties in the form of Rectal Suppositories." Natural and Engineering Sciences 9, no. 2 (2024): 407–25. http://dx.doi.org/10.28978/nesciences.1465276.

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AIM: To evaluate the clinical efficiency of phytocomposition with prostate-protective properties in the form of rectal suppositories. METHODS: The analysis of literature information was performed to assess literature data and form an evidence base for the ratio between the levels of clinical effectiveness and safety for phytocomposition with prostate-protective properties in the form of rectal suppositories. To assess the clinical efficiency and safety the authors used a literature review on the ground of databases PubMed, MEDLINE, Web of Science, and Scopus. RESULTS: The functional characteri

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34

Bonnar-Pizzorno, Raven M., Alyson J. Littman, Mark Kestin, and Emily White. "Saw Palmetto Supplement Use and Prostate Cancer Risk." Nutrition and Cancer 55, no. 1 (2006): 21–27. http://dx.doi.org/10.1207/s15327914nc5501_3.

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35

Wargo, Kurt A., Elena Allman, and Farrah Ibrahim. "A Possible Case of Saw Palmetto–Induced Pancreatitis." Southern Medical Journal 103, no. 7 (2010): 683–85. http://dx.doi.org/10.1097/smj.0b013e3181e1e3ee.

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36

MOON, MARY ANN. "For BPH, Saw Palmetto No Better Than Placebo." Family Practice News 41, no. 17 (2011): 10. http://dx.doi.org/10.1016/s0300-7073(11)70888-x.

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37

MOON, MARY ANN. "Saw Palmetto No Better Than Placebo for BPH." Internal Medicine News 44, no. 17 (2011): 42. http://dx.doi.org/10.1016/s1097-8690(11)70883-6.

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38

Trinachartvanit, Wachareeporn, Bettina M. Francis, and A. Lane Rayburn. "Saw palmetto extract induces nuclear heterogeneity in mice." Environmental Toxicology and Pharmacology 27, no. 1 (2009): 149–54. http://dx.doi.org/10.1016/j.etap.2008.09.006.

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39

Cartwright, Elizabeth J., Margaret H. Dohnalek та W. Stephen Hill. "Lipid Profile and 5α-Reductase Inhibition Activity of Proprietary Ultrahigh-Pressure Supercritical Carbon Dioxide and Hexane Saw Palmetto Extracts". Uro 3, № 1 (2023): 27–39. http://dx.doi.org/10.3390/uro3010005.

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Inhibition of 5α-reductase (5αR), which blocks the conversion of testosterone to its active metabolite, dihydrotestosterone, has been shown to impact further prostate enlargement (benign prostatic hyperplasia, or BPH). Clinical trials of standardized lipidosterolic extracts of Serenoa repens (LSESr), also known as standardized extracts of saw palmetto, have demonstrated improvement in lower urinary tract symptoms (LUTS) and delayed progression of BPH. The aim of this preclinical study was to compare two standardized LSESr, a proprietary ultrahigh-pressure supercritical carbon dioxide extract o

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40

Singh, Y. N., A. K. Devkota, D. C. Sneeden, K. K. Singh, and F. Halaweish. "Hepatotoxicity potential of Saw Palmetto (Serenoa repens) in rats." Phytomedicine 14, no. 2-3 (2007): 204–8. http://dx.doi.org/10.1016/j.phymed.2006.03.024.

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41

Avins, Andrew L., Stephen Bent, Suzanne Staccone, et al. "A detailed safety assessment of a saw palmetto extract." Complementary Therapies in Medicine 16, no. 3 (2008): 147–54. http://dx.doi.org/10.1016/j.ctim.2007.10.005.

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42

Bennett, Bradley C., and Judith R. Hicklin. "Uses of saw palmetto (Serenoa repens, Arecaceae) in Florida." Economic Botany 52, no. 4 (1998): 381–93. http://dx.doi.org/10.1007/bf02862068.

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43

Jipescu, Daniel, Aman Patel, Hema Bohra, and Amanda Pientka. "RARE CASE OF SAW PALMETTO INDUCED COMPLETE HEART BLOCK." Journal of the American College of Cardiology 69, no. 11 (2017): 2310. http://dx.doi.org/10.1016/s0735-1097(17)35699-1.

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44

Wilt, Timothy J., Areef Ishani, Gerold Stark, Roderick MacDonald, Joseph Lau, and Cynthia Mulrow. "Saw Palmetto Extracts for Treatment of Benign Prostatic Hyperplasia." JAMA 280, no. 18 (1998): 1604. http://dx.doi.org/10.1001/jama.280.18.1604.

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45

Pradeep Kumar, Papegowda. "Physico-Mechanical, Thermal and Morphological Studies of Saw Palmetto Spent - HDPE Composites." International Journal of Scientific Engineering and Research 5, no. 5 (2017): 164–68. https://doi.org/10.70729/ijser151433.

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46

Lowe, Franklin C. "Saw Palmetto Berry in the Treatment of Benign Prostatic Hyperplasia." Clinical Research and Regulatory Affairs 14, no. 1 (1997): 53–66. http://dx.doi.org/10.3109/10601339709019441.

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47

Liu, Meng, Huirong Yin, Fang Wang, and Ying Tian. "The Therapeutic Potential of Saw Palmetto Extract in Urological Disorders." Natural Product Communications 16, no. 11 (2021): 1934578X2110596. http://dx.doi.org/10.1177/1934578x211059635.

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Saw palmetto extract (SPE) has been widely used as a therapeutic remedy for urinary dysfunction in western countries. Furthermore, as an herb drug, it can be used as an alternative therapy for benign prostatic hyperplasia (BPH) due to its safety and minimum adverse effects. Reportedly, SPE improves the urinary symptoms, which mainly depend on anti-androgenic effects and effects on autonomic receptors in the lower urinary tract. However, the mechanisms of action responsible for the therapeutic roles of SPE have not been fully elucidated. Relevant studies indicate that SPE has some positive effe

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48

Penugonda, Kavitha, and Brian Lindshield. "Fatty Acid and Phytosterol Content of Commercial Saw Palmetto Supplements." Nutrients 5, no. 9 (2013): 3617–33. http://dx.doi.org/10.3390/nu5093617.

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49

Yamada, Shizuo, and Yoshihisa Kato. "Effects of saw palmetto extract on the vanilloid receptor TRPV1." LUTS: Lower Urinary Tract Symptoms 14, no. 2 (2021): 117–21. http://dx.doi.org/10.1111/luts.12413.

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50

Spurgeon, David. "Saw palmetto extract is not effective for benign prostatic hyperplasia." BMJ 332, no. 7537 (2006): 323.1. http://dx.doi.org/10.1136/bmj.332.7537.323.

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