Log in

Relevant bibliographies by topics / Scag / Journal articles

To see the other types of publications on this topic, follow the link: Scag.

Journal articles on the topic 'Scag'

Author: Grafiati

Published: 28 July 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Scag.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Chanda, Jayeeta, Sabnam Sengupta, Ananya Kanjilal, and Swapan Bhattacharya. "SCAG." ACM SIGSOFT Software Engineering Notes 36, no. 5 (2011): 1–6. http://dx.doi.org/10.1145/2020976.2020981.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Fosso Wamba, Samuel, and Shahriar Akter. "Understanding supply chain analytics capabilities and agility for data-rich environments." International Journal of Operations & Production Management 39, no. 6/7/8 (2019): 887–912. http://dx.doi.org/10.1108/ijopm-01-2019-0025.

Full text

Abstract:

Purpose Big data-driven supply chain analytics capability (SCAC) is now emerging as the next frontier of supply chain transformation. Yet, very few studies have been directed to identify its dimensions, subdimensions and model their holistic impact on supply chain agility (SCAG) and firm performance (FPER). Therefore, to fill this gap, the purpose of this paper is to develop and validate a dynamic SCAC model and assess both its direct and indirect impact on FPER using analytics-driven SCAG as a mediator. Design/methodology/approach The study draws on the emerging literature on big data, the re

APA, Harvard, Vancouver, ISO, and other styles

3

Margarido, Regina Célia Cardoso, Paulo Roberto Leme, Saulo da Luz e. Silva, and Angélica Simone Cravo Pereira. "Níveis de concentrado e sais de cálcio de ácidos graxos para novilhos terminados em confinamento." Ciência Rural 41, no. 2 (2011): 330–36. http://dx.doi.org/10.1590/s0103-84782011000200025.

Full text

Abstract:

Objetivou-se avaliar o efeito do nível de concentrado e dos sais de cálcio de ácidos graxos (SCAG) sobre o desempenho e qualidade da carne de novilhos terminados em confinamento. Sessenta novilhos Nelore e cruza Nelore foram divididos em quatro grupos e confinados por um período de 85 dias com as seguintes dietas: (BC) 46,7% de concentrado; (BC-SCAG) dieta BC acrescida de 3% de SCAG; (AC) dieta contendo 76,6% de concentrado e (AC-SCAG) dieta AC com 3% de SCAG. O nível de concentrado não influenciou o ganho médio diário, a espessura de gordura subcutânea e a área de olho de lombo, mas as dietas

APA, Harvard, Vancouver, ISO, and other styles

4

Lopes-Cendes, Iscia, Carlos E. Steiner, Isabel Silveira, Walter Pinto-Junior, Jayme A. Maciel, and Guy A. Rouleau. "Clinical and molecular characteristics of a Brazilian family with spinocerebellar ataxia type 1." Arquivos de Neuro-Psiquiatria 54, no. 3 (1996): 412–18. http://dx.doi.org/10.1590/s0004-282x1996000300009.

Full text

Abstract:

The spinocerebellar ataxias (SCAs) are a clinically and genetically heterogeneous group of late onset neurodegenerative disorders. To date, seven different genes causing autosomal dominant SCA have been mapped: SCA1, SCA2, Machado-Joseph disease (MJD)/SCA3, SCA4, SCA5, SCA7 and dentatorubropallidoluysian atrophy (DRPLA). Expansions of an unstable trinucleotide CAG repeat cause three of these disorders: SCA1, MJD/SCA3 and DRPLA. We studied one Brazilian family segregating an autosomal dominant type of SCA. A total of ten individuals were examined and tested for the presence of the SCA1, MJD and

APA, Harvard, Vancouver, ISO, and other styles

5

Lee, Chia-Ju, and Chin-San Liu. "A Review of Spinocerebellar Ataxias in Taiwan." Acta Neurologica Taiwanica 34, no. 2 (2025): 55–63. https://doi.org/10.4103/ant.ant_113_0057.

Full text

Abstract:

Abstract Spinocerebellar ataxias (SCAs) are a group of neurodegenerative diseases characterized by inherited progressive cerebellar ataxia with or without other associated features. The clinical presentations of these affected SCA patients are very heterogeneous. Genetic testing has been performed in the Taiwanese population to determine the prevalence of SCAs in Taiwan. In general, the diseases can be classified as those caused by tandem repeats and those with conventional mutations. Among the SCAs caused by tandem repeats, polyglutamine SCAs, including SCA1, SCA2, SCA3, SCA6, SCA7, and SCA17

APA, Harvard, Vancouver, ISO, and other styles

6

Sokolovsky, N., A. Cook, H. Hunt, P. Giunti, and L. Cipolotti. "A Preliminary Characterisation of Cognition and Social Cognition in Spinocerebellar Ataxia Types 2, 1, and 7." Behavioural Neurology 23, no. 1-2 (2010): 17–29. http://dx.doi.org/10.1155/2010/395045.

Full text

Abstract:

Over the last decade, studies have implicated the cerebellum not only in motor functioning, but also in cognition and social cognition. Although some aspects of cognition have been explored in the five most common forms of Spinocerebellar Ataxia (SCA), social cognition in these patients has rarely been examined. The present study provides a preliminary characterisation of the severity of cognitive and social cognitive impairments in patients with SCA2, SCA1 and SCA7 using an identical battery to the one previously used in SCA3 and SCA6 patients for comparison. The cognitive profiles of SCA1 an

APA, Harvard, Vancouver, ISO, and other styles

7

Freund, Aline Andrade, Rosana Hermínia Scola, Hélio A. G. Teive, et al. "Spinocerebellar ataxias: microsatellite and allele frequency in unaffected and affected individuals." Arquivos de Neuro-Psiquiatria 67, no. 4 (2009): 1124–32. http://dx.doi.org/10.1590/s0004-282x2009000600034.

Full text

Abstract:

The diagnosis and incidence of spinocerebelar ataxias (SCA) is sometimes difficult to analyze due the overlap of phenotypes subtypes and are disorders of mutations caused by CAG trinucleotide repeat expansion. To investigate the incidence of the SCA in Southern Brazil, we analyzed the trinucleotide repeats (CAG)n at the SCA1, SCA2, SCA3, SCA6 and SCA7 loci to identify allele size ranges and frequencies. We examined blood sample from 154 asymptomatic blood donors and 115 individuals with progressive ataxias. PCR products were submitted to capillary electrophoresis. In the blood donors, the rang

APA, Harvard, Vancouver, ISO, and other styles

8

Iqbal, Rashid, Zahid Ali, S. Jalali-Asadabadi, and Iftikhar Ahmad. "Electron correlation and spin-orbit coupling effects in scandium intermetallic compounds ScTM (TM = Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag and Au)." International Journal of Modern Physics B 31, no. 32 (2017): 1750263. http://dx.doi.org/10.1142/s0217979217502630.

Full text

Abstract:

Spin-polarized density functional calculations are performed to study the correlation and spin-orbit coupling (SOC) effects in scandium intermetallic compounds viz. ScTM (TM[Formula: see text]=[Formula: see text]Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag and Au) using FP-LAPW[Formula: see text]+[Formula: see text]lo method. The LDA, LDA[Formula: see text]+[Formula: see text]U and LDA[Formula: see text]+[Formula: see text]U[Formula: see text]+[Formula: see text]SOC exchange-correlation functionals are used to calculate the structural parameters and we found that the LDA[Formula: see text]+[Formula: see tex

APA, Harvard, Vancouver, ISO, and other styles

9

Zilenovski, A. M., J. L. P. Mattos Filho, and R. O. Santos. "A Modified SCAG Scale in Portuguese." Clinical Gerontologist 10, no. 2 (1991): 47–66. http://dx.doi.org/10.1300/j018v10n02_05.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Orr, Harry T. "Cell biology of spinocerebellar ataxia." Journal of Cell Biology 197, no. 2 (2012): 167–77. http://dx.doi.org/10.1083/jcb.201105092.

Full text

Abstract:

Ataxia is a neurological disorder characterized by loss of control of body movements. Spinocerebellar ataxia (SCA), previously known as autosomal dominant cerebellar ataxia, is a biologically robust group of close to 30 progressive neurodegenerative diseases. Six SCAs, including the more prevalent SCA1, SCA2, SCA3, and SCA6 along with SCA7 and SCA17 are caused by expansion of a CAG repeat that encodes a polyglutamine tract in the affected protein. How the mutated proteins in these polyglutamine SCAs cause disease is highly debated. Recent work suggests that the mutated protein contributes to p

APA, Harvard, Vancouver, ISO, and other styles

11

Silva, Saulo da Luz e., Paulo Roberto Leme, Soraia Marques Putrino, Amaury Camilo Valinote, José Carlos Machado Nogueira Filho, and Dante Pazzanese Duarte Lanna. "Milho grão seco ou úmido com sais de cálcio de ácidos graxos para novilhos Nelore em confinamento." Revista Brasileira de Zootecnia 36, no. 5 (2007): 1426–34. http://dx.doi.org/10.1590/s1516-35982007000600028.

Full text

Abstract:

Objetivou-se com este trabalho avaliar os efeitos do milho grão seco ou úmido e dos sais de cálcio de ácidos graxos no desempenho e nas características de carcaça de novilhos Nelore confinados na fase de terminação. Quarenta e oito animais com peso inicial de 431 ± 29,8 kg foram alimentados durante 70 dias com uma das seguintes dietas: MGS - dieta basal composta de silagem de milho (40%), milho grão seco (48,4%), farelo de soja (7,6%), uréia, sufato de amônia, cloreto de potássio, sal mineral, rúmen tamponante e rumensina (4%); MGU - dieta basal, com substituição do MGS por milho grão úmido; M

APA, Harvard, Vancouver, ISO, and other styles

12

Menshikov, I. V., A. V. Sergeev, V. Yu Cherebillo, and V. A. Kislukhin. "Intraoperative selective cerebral angiography for microsurgical treatment of cerebral arteriovenous malformations in a hybrid operating room." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 2 (February 22, 2024): 225–35. http://dx.doi.org/10.33920/med-01-2402-06.

Full text

Abstract:

Arteriovenous malformations (AVMs) of the brain are a congenital anomaly of the development of cerebral vessels, when instead of a normal capillary bed, a «network» of pathologically altered vessels is formed, through which arterial blood is shunted into the drainage venous system. Due to the thinned wall of the pathological vessels and high pressure in them, patients with AVMs are at risk of intracerebral hemorrhage up to 4 % annually, which determines the vital need for their treatment. Microsurgical removal of brain AVMs is considered the most radical and effective treatment method, the mai

APA, Harvard, Vancouver, ISO, and other styles

13

Liao, Yu Bo, Zhao Sheng Lai, Yao Yong Meng, and Ping Li Zhang. "Surface-Enhanced Raman Spectroscopic Study of Calf Thymus DNA on Two Different Silver Colloids." Advanced Materials Research 781-784 (September 2013): 1072–75. http://dx.doi.org/10.4028/www.scientific.net/amr.781-784.1072.

Full text

Abstract:

Two different silver colloids were produced by the reduction of AgNO3using sodium citrate (SCAg colloid) or hydroxylamine hydrochloride (HHAg colloid) as reductant. A comparative study was made on SERS spectra (λexc=514.5 nm) of the calf thymus DNA on the two silver colloids in solution of 0.06mol/L NaCl, pH7.0. With the SCAg colloid, the bands at 732, 915, 1340, and 1448 cm-1for adenine, and 800, 1180, 1590, 1625 and 1651 cm-1for thymidine are dramatically enhanced. It shows that the DNA molecules can be oriented relatively perpendicularly to the SCAg colloidal surface via the N6H2, N7 of ade

APA, Harvard, Vancouver, ISO, and other styles

14

Coarelli, Giulia, Alexis Brice, and Alexandra Durr. "Recent advances in understanding dominant spinocerebellar ataxias from clinical and genetic points of view." F1000Research 7 (November 12, 2018): 1781. http://dx.doi.org/10.12688/f1000research.15788.1.

Full text

Abstract:

Abstract Spinocerebellar ataxias (SCAs) are rare types of cerebellar ataxia with a dominant mode of inheritance. To date, 47 SCA subtypes have been identified, and the number of genes implicated in SCAs is continually increasing. Polyglutamine (polyQ) expansion diseases (ATXN1/SCA1, ATXN2/SCA2, ATXN3/SCA3, CACNA1A/SCA6, ATXN7/SCA7, TBP/SCA17, and ATN1/DRPLA) are the most common group of SCAs. No preventive or curative treatments are currently available, but various therapeutic approaches, including RNA-targeting treatments, such as antisense oligonucleotides (ASOs), are being developed. Clinic

APA, Harvard, Vancouver, ISO, and other styles

15

Pagliano, F. M., and G. C. Galbiati. "Comparison of the Efficacy and Safety of Daily Dosages of 6 mg and 20 mg Dihydroergocristine in the Treatment of Chronic Cerebro-Vascular Disease." Journal of International Medical Research 23, no. 4 (1995): 219–27. http://dx.doi.org/10.1177/030006059502300401.

Full text

Abstract:

The efficacy and safety of two different regimens of dihydroergocristine, in the treatment of patients with chronic cerebro-vascular disease, were compared in this double-blind study. Forty out-patients, 11 males and 29 females, aged 55 – 80 years were randomly assigned to treatment with 6 or 20 mg dihydroergocristine, daily, for 3 months. The Sandoz Clinical Assessment for Geriatrics (SCAG) scale was used to assess the efficacy of treatment. Both doses induced a statistically significant improvement ( P < 0.01) in total SCAG scores after both 45 and 90 days of treatment. The higher dose pr

APA, Harvard, Vancouver, ISO, and other styles

16

Shrimankar, J., Som D. Soni, and J. McMurray. "Dexamethasone Suppression Test in Dementia and Depression." British Journal of Psychiatry 154, no. 3 (1989): 372–77. http://dx.doi.org/10.1192/bjp.154.3.372.

Full text

Abstract:

To determine the usefulness of the DST in differentiating depression from dementia, the test was administered to three diagnostic groups of psychogeriatric patients: depression; dementia; and dementia with depression. Clinical assessments were supplemented by ratings on the HRSD and SCAG, as well as by EEG and CT. All three groups showed a high incidence of abnormal DST results unrelated to presence or severity of affective symptoms, but showing a better association with SCAG and its ‘organic’ subsets. The mechanism(s) underlying these abnormal results may reflect organic brain disease. The us

APA, Harvard, Vancouver, ISO, and other styles

17

Scarabino, Daniela, Liana Veneziano, Alessia Fiore, et al. "Leukocyte Telomere Length Variability as a Potential Biomarker in Patients with PolyQ Diseases." Antioxidants 11, no. 8 (2022): 1436. http://dx.doi.org/10.3390/antiox11081436.

Full text

Abstract:

SCA1, SCA2, and SCA3 are the most common forms of SCAs among the polyglutamine disorders, which include Huntington’s Disease (HD). We investigated the relationship between leukocyte telomere length (LTL) and the phenotype of SCA1, SCA2, and SCA3, comparing them with HD. The results showed that LTL was significantly reduced in SCA1 and SCA3 patients, while LTL was significantly longer in SCA2 patients. A significant negative relationship between LTL and age was observed in SCA1 but not in SCA2 subjects. LTL of SCA3 patients depend on both patient’s age and disease duration. The number of CAG re

APA, Harvard, Vancouver, ISO, and other styles

18

Kraft, Scott, Sarah Furtado, Ranjit Ranawaya, et al. "Adult Onset Spinocerebellar Ataxia in a Canadian Movement Disorders Clinic." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 32, no. 4 (2005): 450–58. http://dx.doi.org/10.1017/s0317167100004431.

Full text

Abstract:

ABSTRACT:Background:The spinocerebellar ataxias (SCAs) are a genetically and clinically heterogeneous group of neurodegenerative disorders. Relative frequencies vary within different ethnic groups and geographical locations.Objectives:1) To determine the frequencies of hereditary and sporadic adult onset SCAs in the Movement Disorders population; 2) to assess if the fragile X mental retardation gene 1 (FMR1) premutation is found in this population.Methods:A retrospective chart review of individuals with a diagnosis of adult onset SCA was carried out. Testing for SCA types 1, 2, 3, 6, 7, and 8,

APA, Harvard, Vancouver, ISO, and other styles

19

Block, Robert I., Marlene Devoe, Mary Russell, and Nunzio Pomara. "Clinical Ratings: Relationship to Objective Psychometric Assessment in Individuals with Dementia." Psychological Reports 57, no. 1 (1985): 183–89. http://dx.doi.org/10.2466/pr0.1985.57.1.183.

Full text

Abstract:

The efficacy of drugs for the treatment of memory impairment in elderly patients with dementia is frequently established by a combination of subjective and objective psychological assessments. Often these assessments produce conflicting results. To throw some light on the relation between subjective and objective assessments, we examined the correlations of subjective ratings on the Sandoz Clinical Assessment—Geriatric (SCAG) and scores on objective cognitive tests of demented patients (9 men and 14 women) being screened for participation in an experimental drug trial. Our results showed agree

APA, Harvard, Vancouver, ISO, and other styles

20

Silveira, M. F., J. Restle, L. F. G. Menezes, I. L. Brondani, J. L. Nörnberg, and A. M. Callegaro. "Metabólitos sanguíneos de vacas de corte suplementadas ou não com sais de cálcio de ácidos graxos durante o período pré e/ou pós-parto." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 64, no. 6 (2012): 1418–26. http://dx.doi.org/10.1590/s0102-09352012000600003.

Full text

Abstract:

Avaliou-se a concentração de metabólitos sanguíneos de vacas de corte mantidas em pastagem natural recebendo suplementação com sais de cálcio de ácidos graxos (SCAG) durante 45 dias antes do parto (PRE), suplementação com SCAG durante 45 dias antes do parto e 63 dias pós-parto (PREPOS), suplementação com SCAG durante 63 dias pós-parto (POS) e de vacas não suplementadas (PN). As coletas de sangue foram realizadas em média 64 dias antes do parto, e aos 21, 42 e 63 dias pós-parto. Não ocorreu interação significativa entre tratamentos e períodos. As concentrações plasmáticas de β-hidroxibutirato (

APA, Harvard, Vancouver, ISO, and other styles

21

Ikhrata, Hasan, and Patrick Michell. "Technical Report of Southern California Association of Governments’ Transportation Performance Indicators." Transportation Research Record: Journal of the Transportation Research Board 1606, no. 1 (1997): 103–14. http://dx.doi.org/10.3141/1606-13.

Full text

Abstract:

The overall goal of the staff of the Southern California Association of Governments (SCAG) is to develop specific, quantifiable, and easily understandable performance indicators for the region’s transportation system that better inform elected officials and policy boards of the broad array of choices for investing public and private funds. SCAG’s performance indicators are intended to capture the important relationships between transportation and a diversity of public policy concerns. The seven performance indicators used in the preparation of the 1997 Regional Transportation Plan (RTP) are mo

APA, Harvard, Vancouver, ISO, and other styles

22

Moro, Adriana, Renato Puppi Munhoz, Walter Oleschko Arruda, Salmo Raskin, and Hélio Afonso Ghizoni Teive. "Clinical relevance of "bulging eyes" for the differential diagnosis of spinocerebellar ataxias." Arquivos de Neuro-Psiquiatria 71, no. 7 (2013): 428–30. http://dx.doi.org/10.1590/0004-282x20130056.

Full text

Abstract:

ObjectiveTo investigate the relevance of the clinical finding of bulging eyes (BE) in a large Brazilian cohort of spinocerebellar ataxias (SCA), to assess its importance in clinical differential diagnosis among SCA.MethodsThree hundred sixty-nine patients from 168 Brazilian families with SCA were assessed with neurological examination and molecular genetic testing. BE was characterized by the presence of eyelid retraction. Genetically ascertained SCA3 was detected in 167 patients, SCA10 in 68 patients, SCA2 in 20, SCA1 in 9, SCA7 in 6, and SCA6 in 3 patients.ResultsBE was detected in 123 patie

APA, Harvard, Vancouver, ISO, and other styles

23

Durr, Alexandra, Giovanni Stevanin, Geraldine Cancel, Olivier Didierjean, and Alexis Brice. "Phenotype-genotype correlations in SCA1, SCA2, SCA3/MJD and SCA6." Neuromuscular Disorders 7, no. 6-7 (1997): 469. http://dx.doi.org/10.1016/s0960-8966(97)87331-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Gómez, Rocío, Yessica S. Tapia-Guerrero, Bulmaro Cisneros, et al. "Genetic Distribution of Five Spinocerebellar Ataxia Microsatellite Loci in Mexican Native American Populations and Its Impact on Contemporary Mestizo Populations." Genes 13, no. 1 (2022): 157. http://dx.doi.org/10.3390/genes13010157.

Full text

Abstract:

Spinocerebellar ataxias (SCAs) conform a heterogeneous group of neurodegenerative disorders with autosomal dominant inheritance. Five of the most frequent SCAs are caused by a CAG repeat expansion in the exons of specific genes. The SCAs incidence and the distribution of polymorphic CAG alleles vary among populations and ethnicities. Thus, characterization of the genetic architecture of ethnically diverse populations, which have undergone recent admixture and demographic events, could facilitate the identification of genetic risk factors. Owing to the great ethnic diversity of the Mexican popu

APA, Harvard, Vancouver, ISO, and other styles

25

Ambrosio, L. A., G. Marchese, A. Filippo, E. Romano, and R. Musacchio. "The Effect of Mesoglycan in Patients with Cerebrovascular Disease: A Psychometric Evaluation." Journal of International Medical Research 21, no. 3 (1993): 138–46. http://dx.doi.org/10.1177/030006059302100304.

Full text

Abstract:

Mesoglycan is a preparation of natural glycosaminoglycans, containing mainly heparan sulphate and dermatan sulphate. A clinical trial was conducted to evaluate the efficacy and the tolerability of once-daily mesoglycan in 30 patients with clinical evidence of cerebrovascular insufficiency. Clinical effectiveness was assessed using psychometric and neurological scales: Sandoz Clinical Assessment for Geriatric Patients (SCAG); Parkside Behaviour Rating Scale Modified; Geriatric Depression Scale; and Anxiety Evaluation. Mesoglycan was given as a single oral once-daily dose of 100 mg for a period

APA, Harvard, Vancouver, ISO, and other styles

26

Park, Hyeyoung, Han-Joon Kim, and Beom S. Jeon. "Parkinsonism in Spinocerebellar Ataxia." BioMed Research International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/125273.

Full text

Abstract:

Spinocerebellar ataxia (SCA) presents heterogeneous clinical phenotypes, and parkinsonism is reported in diverse SCA subtypes. Both levodopa responsive Parkinson disease (PD) like phenotype and atypical parkinsonism have been described especially in SCA2, SCA3, and SCA17 with geographic differences in prevalence. SCA2 is the most frequently reported subtype of SCA related to parkinsonism worldwide. Parkinsonism in SCA2 has unique genetic characteristics, such as low number of expansions and interrupted structures, which may explain the sporadic cases with low penetrance. Parkinsonism in SCA17

APA, Harvard, Vancouver, ISO, and other styles

27

Kim, Ji Yeon, Sung Sup Park, Se-Ick Joo, Jong-Min Kim, and Beom S. Jeon. "Molecular Analysis of Spinocerebellar Ataxias in Koreans: Frequencies and Reference Ranges of SCA1, SCA2, SCA3, SCA6, and SCA7." Molecules and Cells 12, no. 3 (2001): 336–41. http://dx.doi.org/10.1016/s1016-8478(23)17105-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Moreira Lemos, Julia, Jonathan Jordão De Mello Fernandes, Giovanna Cristina Dourado Faria, Ana Luíza Quevedo, and Luiz Antonio Lupi Junior. "ATAXIA ESPINOCEREBELAR: UMA REVISÃO INTEGRATIVA SOBRE SCA1, SCA2, SCA3 E SCA6." Brazilian Journal of Implantology and Health Sciences 6, no. 6 (2024): 2036–67. http://dx.doi.org/10.36557/2674-8169.2024v6n6p2036-2067.

Full text

Abstract:

As ataxias espinocerebelares (SCAs) são doenças dominantes geneticamente adquiridas que causam neurodegeneração. Apesar de afetarem principalmente o cerebelo e a medula espinal, outras áreas do sistema nervoso, como os gânglios da base e o córtex cerebral, também são impactadas, comprometendo a execução precisa dos movimentos. Os sintomas incluem hipotonia postural, distúrbios oculomotores, marcha atáxica, atrofia cerebelar e disfunções respiratórias e da fala. Desde 2006, a Escala de Avaliação e Classificação de Ataxia (SARA) é usada para diagnosticar e determinar a gravidade da ataxia. Não e

APA, Harvard, Vancouver, ISO, and other styles

29

Blake, Kim, Nicolle Vincent, Susan Wakefield, Joseph Murphy, Karen Mann, and Matthew Kutcher. "A structured communication adolescent guide (SCAG): assessment of reliability and validity." Medical Education 39, no. 5 (2005): 482–91. http://dx.doi.org/10.1111/j.1365-2929.2005.02123.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

An, Haejoon, Heesang Ko, Hongwoo Kim, et al. "Modeling and voltage-control of variable-speed SCAG-based wind farm." Renewable Energy 42 (June 2012): 28–35. http://dx.doi.org/10.1016/j.renene.2011.09.029.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Xu, Qi, Yoav Barak, Rina Kenig, Yuval Shoham, Edward A. Bayer, and Raphael Lamed. "A Novel Acetivibrio cellulolyticus Anchoring Scaffoldin That Bears Divergent Cohesins." Journal of Bacteriology 186, no. 17 (2004): 5782–89. http://dx.doi.org/10.1128/jb.186.17.5782-5789.2004.

Full text

Abstract:

ABSTRACT Sequencing of a cellulosome-integrating gene cluster in Acetivibrio cellulolyticus was completed. The cluster contains four tandem scaffoldin genes (scaA, scaB, scaC, and scaD) bounded upstream and downstream, respectively, by a presumed cellobiose phosphorylase and a nucleotide methylase. The sequences and properties of scaA, scaB, and scaC were reported previously, and those of scaD are reported here. The scaD gene encodes an 852-residue polypeptide that includes a signal peptide, three cohesins, and a C-terminal S-layer homology (SLH) module. The calculated molecular weight of the

APA, Harvard, Vancouver, ISO, and other styles

32

Elwan, O., AA Helmy, ME Tamawy, et al. "Ergoloids and Ischaemic Strokes; Efficacy and Mechanism of Action." Journal of International Medical Research 23, no. 3 (1995): 154–66. http://dx.doi.org/10.1177/030006059502300302.

Full text

Abstract:

In this double-blind, randomized study the efficacy of the ergoloid compounds, co-dergocrine mesylate and nicergoline, in the rehabilitation of patients with ischaemic stroke was investigated. A group of 30 patients was treated daily with 60 mg nicergoline, orally, and a second group of 27 patients was given 1.8 – 6 mg co-dergocrine mesylate, orally or intramuscularly, daily (depending on the time since the initial ischaemic insult) for 6 months. Outcome measures included: motoricity index (limb function); Sandoz Clinical Assessment Geriatric (SCAG) scale; psychometric tests to assess function

APA, Harvard, Vancouver, ISO, and other styles

33

Joukhadar, Nadim, Genna Bourget, Sarah Manos, Karen Mann, Jill Hatchette, and Kim Blake. "Skills for Interviewing Adolescent Patients: Sustainability of Structured Feedback in Undergraduate Education on Performance in Residency." Journal of Graduate Medical Education 8, no. 3 (2016): 422–25. http://dx.doi.org/10.4300/jgme-d-15-00297.1.

Full text

Abstract:

ABSTRACT Effective adolescent (10 to 19 years) interviewing by physicians is an essential skill that many trainees can find challenging.Background We assessed whether structured adolescent interviewing using standardized patients (SPs) and feedback in undergraduate medical education (UME) has a sustained effect on residents' skills.Objective Postgraduate year (PGY) 1 residents conducted interviews with a SP adolescent–mother pair. The SPs independently scored each PGY-1 interview using the structured communication adolescent guide (SCAG). Unpaired t tests were conducted comparing “Total-Item”

APA, Harvard, Vancouver, ISO, and other styles

34

Basu, Priyadarshi, Biswanath Chattopadhyay, Prasanta K. Gangopadhaya, et al. "Analysis of CAG repeats in SCA1, SCA2, SCA3, SCA6, SCA7 and DRPLA loci in spinocerebellar ataxia patients and distribution of CAG repeats at the SCA1, SCA2 and SCA6 loci in nine ethnic populations of eastern India." Human Genetics 106, no. 6 (2000): 597–604. http://dx.doi.org/10.1007/s004390000320.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Basu, Priyadarshi, Biswanath Chattopadhyay, Prasanta K. Gangopadhaya, et al. "Analysis of CAG repeats in SCA1, SCA2, SCA3, SCA6, SCA7 and DRPLA loci in spinocerebellar ataxia patients and distribution of CAG repeats at the SCA1, SCA2 and SCA6 loci in nine ethnic populations of eastern India." Human Genetics 106, no. 6 (2000): 597–604. http://dx.doi.org/10.1007/s004390050031.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Javed, Khadija, Ren Shengbing, Muhammad Asim, and Mudasir Ahmad Wani. "Cross-Project Defect Prediction Based on Domain Adaptation and LSTM Optimization." Algorithms 17, no. 5 (2024): 175. http://dx.doi.org/10.3390/a17050175.

Full text

Abstract:

Cross-project defect prediction (CPDP) aims to predict software defects in a target project domain by leveraging information from different source project domains, allowing testers to identify defective modules quickly. However, CPDP models often underperform due to different data distributions between source and target domains, class imbalances, and the presence of noisy and irrelevant instances in both source and target projects. Additionally, standard features often fail to capture sufficient semantic and contextual information from the source project, leading to poor prediction performance

APA, Harvard, Vancouver, ISO, and other styles

37

Chae, Keun, Kangling Zhang, Li Zhang, et al. "Two SCA (Stigma/Style Cysteine-rich Adhesin) Isoforms Show Structural Differences That Correlate with Their Levels of in Vitro Pollen Tube Adhesion Activity." Journal of Biological Chemistry 282, no. 46 (2007): 33845–58. http://dx.doi.org/10.1074/jbc.m703997200.

Full text

Abstract:

Lily pollen tubes grow adhering to an extracellular matrix produced by the transmitting tract epidermis in a hollow style. SCA, a small (∼9.4 kDa), basic protein plus low esterified pectin from this extracellular matrix are involved in the pollen tube adhesion event. The mode of action for this adhesion event is unknown. We partially separated three SCA isoforms from the lily stigma in serial size exclusion column fractions (SCA1, 9370 Da; SCA2, 9384 Da; SCA3, 9484 Da). Peptide sequencing analysis allowed us to determine two amino acid variations in SCA3, compared with SCA1. For SCA2, however,

APA, Harvard, Vancouver, ISO, and other styles

38

Herrmann, Werner M., and Kurt Stephan. "Moving from the Question of Efficacy to the Question of Therapeutic Relevance: An Exploratory Reanalysis of a Controlled Clinical Study of 130 Inpatients With Dementia Syndrome Taking Piracetam." International Psychogeriatrics 4, no. 1 (1992): 25–44. http://dx.doi.org/10.1017/s1041610292000887.

Full text

Abstract:

The authors reanalyzed previously published data from a prospectively randomized, placebo-controlled, double-blind phase-III study of 130 inpatients with dementia syndrome. The patients in the study had been diagnosed as having suffered from organic brain syndrome (ICD 290), which is the core syndrome of dementia (so-called dementia syndrome) for at least two years. They were treated with piracetam for three months at a dose level of 4,800 mg/d.These data were reexamined in order both to survey the extent of drugrelated improvement and response rates when assessed at different levels and to in

APA, Harvard, Vancouver, ISO, and other styles

39

Tang, Beisha, Chunyu Liu, Lu Shen, et al. "Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG Trinucleotide Repeat Expansion in Patients With Hereditary Spinocerebellar Ataxia From Chinese Kindreds." Archives of Neurology 57, no. 4 (2000): 540. http://dx.doi.org/10.1001/archneur.57.4.540.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Ford, Brian J. "Critical Focus | Feces, from Start to Finish." Microscope 66, no. 4 (2018): 169–80. https://doi.org/10.59082/eedm2541.

Full text

Abstract:

Excerpt: You must know the one about the dung beetle — walks into a bar and asks: “Is this stool taken?” It’s one of the few quotable jokes about excreta. Most are merely impolite (like, “people who complain about constipation are full of crap”). I daresay many of you thought that the title of this column was actually the editor’s comments on this article, scrawled dismissively on the draft and mistakenly set in type. But no — this time I really am looking at excreta. What I find so intriguing is that it has so many synonyms. Most physical human functions have a couple of alternatives (like br

APA, Harvard, Vancouver, ISO, and other styles

41

Yoshii, Fumihito, Hitoshi Tomiyasu, Ryo Watanabe, and Masafuchi Ryo. "MRI Signal Abnormalities of the Inferior Olivary Nuclei in Spinocerebellar Ataxia Type 2." Case Reports in Neurology 9, no. 3 (2017): 267–71. http://dx.doi.org/10.1159/000481303.

Full text

Abstract:

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant spinocerebellar degeneration, associated with extended repeats of the trinucleotide CAG in the ATXN2 gene on the long arm of chromosome 12. Magnetic resonance imaging (MRI) of SCA2 showed significant atrophies of the brainstem, middle cerebellar peduncles, and cerebellum. We report two genetically proven SCA2 patients who showed hypertrophy of the inferior olivary nuclei on proton density- and T2-weighted MRI. This pattern has never been reported in patients with SCA1, SCA3, or SCA6, and may make it possible to differentiate SCA2 fr

APA, Harvard, Vancouver, ISO, and other styles

42

Lopes-Cendesi, Iscia, Hélio G. A. Teive, Maria E. Calcagnotto, et al. "Frequency of the different mutations causing spinocerebellar ataxia (SCA1, SCA2, MJD/SCA3 and DRPLA) in a large group of Brazilian patients." Arquivos de Neuro-Psiquiatria 55, no. 3B (1997): 519–29. http://dx.doi.org/10.1590/s0004-282x1997000400001.

Full text

Abstract:

Spinocerebellar ataxia type 1 (SCA1), spinocerebellar ataxia type 2 (SCA2) and Machado-Joseph disease or spinocerebellar ataxia type 3 (MJD/SCA3) are three distinctive forms of autosomal dominant spinocerebellar ataxia (SCA) caused by expansions of an unstable CAG repeat localized in the coding region of the causative genes. Another related disease, dentatorubropallidoluysian atrophy (DRPLA) is also caused by an unstable triplet repeat and can present as SCA in late onset patients. We investigated the frequency of the SCA1, SCA2, MJD/SCA3 and DRPLA mutations in 328 Brazilian patients with SCA,

APA, Harvard, Vancouver, ISO, and other styles

43

Stepanov, I. V., M. S. Ol’shanskiy, D. Yu Kharitonov, V. V. Dmitriev, A. V. Podoprigora, and A. S. Shcherbinin. "DIAGNOSIS OF CAROTID PARAGANGLIOMA: MULTIDISCIPLINARY ASPECTS." Journal of radiology and nuclear medicine 99, no. 3 (2018): 125–31. http://dx.doi.org/10.20862/0042-4676-2018-99-3-125-131.

Full text

Abstract:

Objective: to enhance the efficiency of diagnosis and treatment of carotid paragangliomas, by introducing of a multidisciplinary approach into clinical practice.Material and methods. A total of 15 cases of paragangliomas have been followed up for 10 years. The age of the patients was 18 to 58 years (mean age 38±12 years). Primary multiple sites of chemodectomas were noted in 2 cases. Bilateral involvement was observed in one case. In the other, two unilateral vascular tumors successively developed with an interval of almost 6 years. A set of studies was conducted, which embraced ultrasound dup

APA, Harvard, Vancouver, ISO, and other styles

44

Brown, Alexander S., Pratap Meera, Banu Altindag, et al. "MTSS1/Src family kinase dysregulation underlies multiple inherited ataxias." Proceedings of the National Academy of Sciences 115, no. 52 (2018): E12407—E12416. http://dx.doi.org/10.1073/pnas.1816177115.

Full text

Abstract:

The genetically heterogeneous spinocerebellar ataxias (SCAs) are caused by Purkinje neuron dysfunction and degeneration, but their underlying pathological mechanisms remain elusive. The Src family of nonreceptor tyrosine kinases (SFK) are essential for nervous system homeostasis and are increasingly implicated in degenerative disease. Here we reveal that the SFK suppressor Missing-in-metastasis (MTSS1) is an ataxia locus that links multiple SCAs. MTSS1 loss results in increased SFK activity, reduced Purkinje neuron arborization, and low basal firing rates, followed by cell death. Surprisingly,

APA, Harvard, Vancouver, ISO, and other styles

45

Heike, Jacobi, Tezenas du Montcel Sophie, Romanzetti Sandro, et al. "Conversion of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 to manifest ataxia (RISCA): a longitudinal cohort study." Lancet Neurology 19, no. 9 (2020): 738–47. https://doi.org/10.5281/zenodo.4570086.

Full text

Abstract:

In this prospective, longitudinal, observational cohort study, based at 14 referral centres in seven European countries, we enrolled children or siblings of patients with SCA1, SCA2, SCA3, or SCA6. Eligible individuals were those without ataxia, defined by a score on the Scale for the Assessment and Rating of Ataxia (SARA) of less than 3; participants had to be aged 18-50 years for children or siblings of patients with SCA1, SCA2, or SCA3, and 35-70 years for children or siblings of patients with SCA6. Study visits took place at recruitment and after 2, 4, and 6 years (plus or minus 3 months).

APA, Harvard, Vancouver, ISO, and other styles

46

Rahman, Md Siddiqur, Yoshitaka Nagai, H. Akiko Popiel, Muzahed Uddin Ahmed, Md Jalal Uddin, and Talsushi Toda. "Genetic testing for Spinocerebellar Ataxias (SCA) in Parkinsonism." Bangladesh Journal of Neuroscience 28, no. 1 (2013): 16–23. http://dx.doi.org/10.3329/bjn.v28i1.17188.

Full text

Abstract:

Objective: The study was conducted to find out Spinocerebellar Ataxias (SCA) by genetic analysis from those presenting with parkinsonism in the Neurology department of Mymensingh Medical College.Materials and methods: A sample of about 5ml blood was collected by venipuncture in EDTA tube with informed consent from the patients following institutional ethics committee approval by genetic study from 7 healthy people and 9 patients. The neurological disorder along with a complete physical and/or psychological, as well as family history and demographic data was recorded with a prescribed questionn

APA, Harvard, Vancouver, ISO, and other styles

47

Oberholzer, A. F., C. Hendriksen, A. U. Monsch, B. Heierli, and H. B. Stähelin. "Safety and Effectiveness of Low-Dose Clozapine in Psychogeriatric Patients: A Preliminary Study." International Psychogeriatrics 4, no. 2 (1992): 187–95. http://dx.doi.org/10.1017/s1041610292001017.

Full text

Abstract:

The short- and long-term treatment tolerance of low-dose clozapine was retrospectively investigated in 18 psychogeriatric patients. Discontinued use of the drug because of side effects or inefficiency was required for only four patients. In the long-term treatment group leukopenia was not observed, and disturbances of liver function appeared to be very infrequent. A second group of seven severely demented psychogeriatric inpatients who were currently being treated with low-dose clozapine underwent a withdrawal study in order to evaluate the therapeutic efficacy of the drug, measured by the NOS

APA, Harvard, Vancouver, ISO, and other styles

48

Christensen, Chris. "The evolving relationship between mathematics and cryptology, 1951–1952: SCAG and the beginnings of SCAMP and NSASAB." Cryptologia 41, no. 4 (2016): 329–87. http://dx.doi.org/10.1080/01611194.2016.1219788.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Seshagiri, Doniparthi V., Pramod Kumar Pal, Sanjeev Jain, and Ravi Yadav. "Optokinetic nystagmus in patients with SCA." Neurology 91, no. 13 (2018): e1255-e1261. http://dx.doi.org/10.1212/wnl.0000000000006250.

Full text

Abstract:

ObjectiveTo characterize the clinical features in patients with spinocerebellar ataxia (SCA) type 1, SCA2, and SCA3 and to evaluate the oculomotor dysfunction by using optokinetic nystagmus (OKN) testing, which may be a sensitive marker.MethodsIn this prospective observational study, all patients underwent detailed neurologic examination with special emphasis on eye movements. OKN was evaluated with a tape. Disease severity was measured with the International Co-Operative Ataxia Rating Scale (ICARS).ResultsA total of 73 genetically confirmed patients were included, of whom 28, 30, and 15 patie

APA, Harvard, Vancouver, ISO, and other styles

50

Rincón, Marco T., Jennifer C. Martin, Vincenzo Aurilia, et al. "ScaC, an Adaptor Protein Carrying a Novel Cohesin That Expands the Dockerin-Binding Repertoire of the Ruminococcus flavefaciens 17 Cellulosome." Journal of Bacteriology 186, no. 9 (2004): 2576–85. http://dx.doi.org/10.1128/jb.186.9.2576-2585.2004.

Full text

Abstract:

ABSTRACT A new gene, designated scaC and encoding a protein carrying a single cohesin, was identified in the cellulolytic rumen anaerobe Ruminococcus flavefaciens 17 as part of a gene cluster that also codes for the cellulosome structural components ScaA and ScaB. Phylogenetic analysis showed that the sequence of the ScaC cohesin is distinct from the sequences of other cohesins, including the sequences of R. flavefaciens ScaA and ScaB. The scaC gene product also includes at its C terminus a dockerin module that closely resembles those found in R. flavefaciens enzymes that bind to the cohesins

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!