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Journal articles on the topic 'SCC-25'

Author: Grafiati
Published: 7 June 2025
Last updated: 2 August 2025

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1

Tang, Xiaoying, Aimin Zhao, and Yanhuan Hong. "Tiazofurin inhibits oral cancer growth in vitro and in vivo via upregulation of miR-204 expression." Tropical Journal of Pharmaceutical Research 19, no. 7 (2020): 1377–82. http://dx.doi.org/10.4314/tjpr.v19i7.6.

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Purpose: To investigate the effect of tiazofurin on proliferation and growth of oral cancer cells, and the associated mechanism(s) of action.Methods: The effect of tiazofurin on the cytotoxicity of SCC-VII and SCC-25 oral cancer cells were measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, while cell apoptosis was determined by flow cytometry. Western blotting was used for assaying proteinexpressions.Results: Tiazofurin inhibited the viability of the oral cancer cells in a concentration-based manner (p < 0.05). Tiazofurin treatment at a dose of 2.0 μM r
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2

Schwarz, Daniel, Ulrike S. Diesterbeck, Sven König, et al. "Microscopic differential cell counts in milk for the evaluation of inflammatory reactions in clinically healthy and subclinically infected bovine mammary glands." Journal of Dairy Research 78, no. 4 (2011): 448–55. http://dx.doi.org/10.1017/s0022029911000574.

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Somatic cell count (SCC) is generally regarded as an indicator of udder health. A cut-off value of 100×103 cells/ml is currently used in Germany to differentiate between normal and abnormal secretion of quarters. In addition to SCC, differential cell counts (DCC) can be applied for a more detailed analysis of the udder health status. The aim of this study was to differentiate somatic cells in foremilk samples of udder quarters classified as normal secreting by SCC <100×103 cells/ml. Twenty cows were selected and 72 normal secreting udder quarters were compared with a control group of six di
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3

Dennis, Cydney D., Jonathan T. Dillon, Prit H. Patel, et al. "Laryngeal Cancer Cells Metabolize 25-Hydroxyvitamin D3 and Respond to 24R,25-dihydroxyvitamin D3 via a Mechanism Dependent on Estrogen Receptor Levels." Cancers 16, no. 9 (2024): 1635. http://dx.doi.org/10.3390/cancers16091635.

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Studies have evaluated vitamin D3’s therapeutic potential in estrogen-responsive cancers, with conflicting findings. We have shown that the proliferation of breast cancer cells is regulated by 24R,25-dihydroxyvitamin D3 (24R,25(OH)2D3) depending on estrogen receptor alpha 66 (ERα66) expression, suggesting that this could also be the case for estrogen-sensitive laryngeal cancer cells. Accordingly, we examined levels of ERα isoforms in ERα66-positive UM-SCC-12 and ERα66-negative UM-SCC-11A cells and their response to 24R,25(OH)2D3. 24R,25(OH)2D3 stimulated proliferation, increased the expression
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4

Wright, Alexi A., Michelle S. Hirsch, Nikhil Wagle, et al. "KRAS and EGFR mutations to distinguish adenocarcinomas and squamous cell carcinomas of the cervix." Journal of Clinical Oncology 30, no. 15_suppl (2012): 5011. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.5011.

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5011 Background: Cervical adenocarcinomas (AC) have higher rates of recurrence and distant metastasis, compared with squamous cell carcinomas (SCC), and decreased survival in advanced disease. Yet, tailored treatments for cervical cancers have not emerged. The aim of this study was to compare the frequency and type of somatic mutations in cervical AC and SCC to identify novel therapeutic targets for both subtypes. Methods: Tumors from 61 patients with cervical cancer (36 AC, 25 SCC) underwent genomic profiling by OncoMap, a multiplexed mass spectrometric genotyping technology that interrogates
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5

Yongle, Qiu, Li Kunshan, Lv Feifei, et al. "Preparation of chitosan modified poly(lactic-co-glycolic acid) nanoparticles containing hawthorn proanthocyanidins: SCC25 cell cycle arrest, antiproliferation, and apoptosis studies." Materials Express 12, no. 11 (2022): 1349–56. http://dx.doi.org/10.1166/mex.2022.2288.

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The present study aims at the preparation of a chitosan-PLGA-based proanthocyanidin from hawthorn fruit loaded nano-system (CS-PLGA-PHL) and investigate its inhibitory effect on SCC-25 cells and the related mechanisms. Methods: CS-PLGA-PHL nanocomposites were constructed by emulsion-solvent evaporation. The effect of CS-PLGA-PHL on the proliferation of human normal squamous epithelial hNOK cells were detected. The antitumor activity of CS-PLGA-PHL on SCC-25 cells were studied by cytotoxicity test, cell cycle and apoptosis analysis. The apoptotic protein and gene expression in SCC-25 cells was
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6

Tjioe, Kellen Cristine, Diovana Melo Cardoso, Sandra Helena Penha Oliveira, and Daniel Galera Bernabé. "Stress hormone norepinephrine incites resistance of oral cancer cells to chemotherapy." Endocrine-Related Cancer 29, no. 4 (2022): 201–12. http://dx.doi.org/10.1530/erc-20-0460.

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This study investigated whether norepinephrine (NE) and epinephrine (E) interfere in the response of head and neck squamous cell carcinoma (SCC) cell lines to cisplatin and explored the mechanisms of chemoresistance. Head and neck SCC-derived cell lines SCC-9, Cal27, SCC-25, and FaDu were stimulated with NE or E and treated with the inhibitory concentration of cisplatin for 24 h. As for adrenergic receptors (ADRB) inhibition, cells were treated with propranolol. The results showed that, when combined with NE, cisplatin effectiveness against SCC-9 and Cal27 but not SCC-25 and FaDu cells were no
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7

Hsu, Cheng-Ming, Pai-Mei Lin, Hsin-Ching Lin, et al. "NVP-BEZ235 Attenuated Cell Proliferation and Migration in the Squamous Cell Carcinoma of Oral Cavities and p70S6K Inhibition Mimics its Effect." International Journal of Molecular Sciences 19, no. 11 (2018): 3546. http://dx.doi.org/10.3390/ijms19113546.

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NVP-BEZ235 or BEZ235 is a dual inhibitor of adenosine triphosphate (ATP)-competitive phosphoinositide 3-kinase (PI3K)/mammalian-target-of-rapamycin (mTOR) and is promising for cancer treatment. Because it targets more than one downstream effector, a dual approach is promising for cancer treatment. The aim of this study was to evaluate the efficacy of NVP-BEZ235 in treating oral cavity squamous cell carcinoma (OSCC). Two human OSCC cell lines, SCC-4 and SCC-25, were used in this study. PI3K-AKT signaling, proliferation, and cell migratory and invasion capabilities of OSCC cells were examined. I
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8

Amar, Sabreen, Amr Helmy Mustafa El-Bolok, Sherif Farouk El-Gayar, and Maii Ibrahim Sholkamy. "Synergistic Cytotoxic Effect of Honey Bee Venom and Cisplatin on Tongue Squamous Cell Carcinoma Cell Line." Open Access Macedonian Journal of Medical Sciences 9, B (2021): 1739–44. http://dx.doi.org/10.3889/oamjms.2021.7672.

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BACKGROUND: Tongue cancer is one of the most common head and neck cancers in the world. Nowadays, natural compounds are important resources of many anti-cancer drugs. Venom from honey bees possesses potent anti-cancer activities. Cisplatin is a chemotherapeutic drug that has been used for decades to treat cancer cells. Recently, combination therapy has been a popular treatment choice for cancer patients. AIM: This study was conducted to evaluate the synergistic cytotoxic effect of honey bee venom (BV) and cisplatin on tongue squamous cell carcinoma 25 (SCC-25) cell lines. METHODS: The cytotoxi
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9

Anjali, Singh, K. Mehta P., and Kumar Rakesh. "Use of Recycled Coarse Aggregate in Self Compacting Concrete." Journal of Indian Chemical Society Vol. 97, No. 10a, Oct 2020 (2020): 1703–8. https://doi.org/10.5281/zenodo.5956943.

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Research Schloar, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, U.P., India Professor, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, U.P., India <em>E-mail</em>: ainasingh65@gmail.com <em>Manuscript received online 20 July 2020, revised and accepted 05 October 2020</em> Self Compacting Concrete (SCC) is gaining popularity in construction industry due to several advantages offered by it. In this study, M-30 grade referral SCC was designed using the natural aggregates, Ordinary Portland Cement (OPC), and varying levels of Fly Ash (FA) for partly repl
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10

Kim, Nah Ihm, and Ji Shin Lee. "Greater specificity of p40 compared with p63 in distinguishing squamous cell carcinoma from adenocarcinoma in effusion cellblocks." Cytojournal 17 (June 8, 2020): 13. http://dx.doi.org/10.25259/cytojournal_78_2019.

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Objective: Squamous cell carcinoma (SCC) rarely causes malignant effusions. Distinguishing between SCC and adenocarcinoma in effusion cytology can be a challenge. p63 and p40 have been frequently used to support squamous cell differentiation in both histological and cytological specimens. However, similar results in cytological preparations of effusion fluids have been rarely reported. This study was designed to assess the diagnostic value of p63 and p40 immunoreactivity for the differentiation of SCC from adenocarcinoma in malignant effusions. Materials and Methods: Immunocytochemical stainin
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11

Meena, A., N. Singh, and S. P. Singh. "Shear strength and microstructural investigation on high-volume fly ash self-compacting concrete containing recycled concrete aggregates and coal bottom ash." Materiales de Construcción 74, no. 353 (2024): e333. http://dx.doi.org/10.3989/mc.2024.354623.

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This article presents the experimental outcomes of the shear strength and microstructural characteristics of high-volume fly ash self-compacting concrete (HVFYA-SCC) containing recycled concrete aggregates and coal bottom ash as partial replacements for natural coarse aggregates and natural fine aggregates. A total of ten numbers of mixes were produced, including HVFYA-SCC made without recycled concrete aggregates and coal bottom ash (as control) along with HVFYA-SCC mixes made with recycled concrete aggregates (from 25% to 50%) and coal bottom ash (from 10% to 30%). The compressive and shear
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12

Zahratul Riadho, Adinda Dwivana Malika, and Wardiansah. "Eyelid Squamous Cell Carcinoma in Palembang, Indonesia: A 5-Year Retrospective Study." Sriwijaya Journal of Ophthalmology 8, no. 1 (2025): 399–412. https://doi.org/10.37275/sjo.v8i1.128.

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Introduction: Eyelid squamous cell carcinoma (SCC) is a prevalent malignancy with potentially severe consequences if not detected and managed early. This study aimed to investigate the prevalence, clinical characteristics, and histopathological features of eyelid SCC patients at Dr. Mohammad Hoesin General Hospital Palembang, Indonesia, over a 5-year period. Methods: A retrospective analysis of medical records was conducted on 20 patients diagnosed with eyelid SCC between 2020 and 2024. Data on demographics, clinical presentation, tumor characteristics, and histopathological findings were coll
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13

Yu, Xiang, Saad Al-Saadi, Isha Kohli, Xiao-Ling Zhao, and R. K. Singh Raman. "Austenitic Stainless-Steel Reinforcement for Seawater Sea Sand Concrete: Investigation of Stress Corrosion Cracking." Metals 11, no. 3 (2021): 500. http://dx.doi.org/10.3390/met11030500.

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Seawater and sea sand concrete (SWSSC) is a highly attractive alternative to normal concrete (NC) that requires huge amounts of fresh water and river sand. However, reinforcements of stainless steel (instead of mild steel that is used in NC) may be required for SWSSC. This article reports investigation of stress corrosion cracking (SCC) of AISI 316 stainless steel (SS) in simulated SWSSC and NC environments, with and without addition of silica to SWSSC and NC, employing slow strain rate testing (SSRT) at 25 and 60 °C. For the purpose of comparison, SCC of SS was also investigated in simulated
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14

Hirakawa, Hitoshi, Taro Ikegami, Norimoto Kise, et al. "Human Papillomavirus Infection and EGFR Exon 20 Insertions in Sinonasal Inverted Papilloma and Squamous Cell Carcinoma." Journal of Personalized Medicine 13, no. 4 (2023): 657. http://dx.doi.org/10.3390/jpm13040657.

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This study aimed to clarify the roles of high-risk human papillomavirus (HR-HPV) infection and epidermal growth factor receptor (EGFR) exon 20 mutations in sinonasal inverted papilloma (IP) and sinonasal squamous cell carcinoma (SNSCC). Samples were collected from 20 cases with IP, 7 with IP and squamous cell carcinoma (IP-SCC), and 20 with SNSCC and examined for HPV infection and EGFR exon 20 mutations. Low- or high-risk HPV DNA was observed in 25% of IP, 57.1% of IP-SCC, and 35% of SNSCC cases. Transcriptionally active HR-HPV infections in IP-SCC and SNSCC, accompanied by p16 overexpression,
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15

Ezhilarasan, D., D. Ali, and R. Varghese. "Sesamol induces cytotoxicity via mitochondrial apoptosis in SCC-25 cells." Human & Experimental Toxicology 40, no. 12_suppl (2021): S423—S433. http://dx.doi.org/10.1177/09603271211047926.

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Sesamol is the main constituent of sesame seed oil and is obtained from Sesamum indicum. Oral squamous cell carcinoma (OSCC) is one of the most common neoplasms affecting the oral cavity. In this study, we investigated the cytotoxic potentials of sesamol on human oral squamous carcinoma (SCC-25) cells. Human oral squamous carcinoma cells were treated with different concentrations (62.5, 125, and 250 μM/mL) of sesamol for 24 h. Cytotoxicity was analyzed by 3- (4, 5- dimethylthiazol -2- yl) -2, 5-diphenyltetrazolium bromide (MTT) assay. Intracellular reactive oxygen species (ROS) expression was
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16

Choi, Byul-Bora, Jeong Hae Choi, Sang-Rye Park, Ji-Young Kim, Jin-Woo Hong, and Gyoo-Cheon Kim. "Scutellariae radixInduces Apoptosis in Chemoresistant SCC-25 Human Tongue Squamous Carcinoma Cells." American Journal of Chinese Medicine 43, no. 01 (2015): 167–81. http://dx.doi.org/10.1142/s0192415x15500111.

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Scutellariae radix is one of the most widely used anticancer herbal medicines in several Asian countries, including Korea, Japan, and China. Squamous cell carcinoma (SCC) is one of the most common head and neck carcinomas, which is highly invasive and metastatic, and can potentially develop chemoresistance. Therefore, new effective treatment methods are urgently needed. We determined the effects of Scutellariae radix on SCC-25 cells using the WST-1 assay, F-actin staining, flow cytometry analysis, immunofluorescence staining, and western blot analysis. Scutellariae radix treatment inhibited SC
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17

Basuony, Shaimaa Ali Hamouda Ali El, and Reham S. Hamed. "Anti-Micro RNA-221 a Promising Genetic Therapy of Oral Squamous Cell Carcinoma (SCC-25)." Brazilian Dental Journal 31, no. 6 (2020): 634–39. http://dx.doi.org/10.1590/0103-6440202003350.

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Abstract Micro-RNA-221(miR-221) is one of oncogenic miRNAs that plays a vital role in the development and progression of oral cancers. The aim of this study is to introduce a new gene therapy for oral squamous cell carcinoma by blocking the expression of oncogenic miR-221 by its inhibitor. The present work was performed on squamous cell carcinoma cell line SCC-25 and anti-miR-221 was delivered to the cells using an ultrasound micro bubbles. Assessment of the effect of miR-221 inhibitor on SCC-25 cells was done using MTT assay, cell cycle analysis and apoptosis detection. In addition, reverse t
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18

Huang, Chun-Chung, Tse-Hua Tung, Chien-Chu Huang, et al. "Electrochemical Assessment of Anticancer Compounds on the Human Tongue Squamous Carcinoma Cells." Sensors 20, no. 9 (2020): 2632. http://dx.doi.org/10.3390/s20092632.

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The most common oral cancer is squamous cell carcinoma (SCC) and its highest occurrence is in the tongue. Almost 30% of patients with one primary head and neck tumor will have a second primary malignancy. In recent studies, two novel plant extracts, andrographolide and cannabidiol (CBD), have been exploited for their anticancer effects. Here, we investigated the cytotoxic effects of these two compounds on SCC-25 cells, a human tongue squamous carcinoma cell line, and compared the outcomes with two chemotherapeutic drugs, cisplatin and fluorouracil. Electric cell substrate impedance sensing (EC
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19

Arivalagan, S. "Flexural behaviour of hybrid fibre (steel fiber and silica fume) reinforced self compacting composite concrete members." World Journal of Engineering 11, no. 4 (2014): 323–30. http://dx.doi.org/10.1260/1708-5284.11.4.323.

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The present day world is witnessing the construction of very challenging and difficult civil engineering structures. Self-compacting concrete (SCC) offers several economic and technical benefits; the use of steel fiber extends its possibilities. Steel fiber acts as a bridge to retard their cracks propagation, and improve several characteristics and properties of the concrete. Therefore, an attempt has been made in this investigation to study the Flexural Behaviour of Steel Fiber Reinforced self compacting concrete incorporating silica fume in the structural elements. The self compacting concre
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20

Moharram, Inas, Walaa Awadin, Mohamed Hamed, M. Salem, and E. Mosbah. "A survey of tumors affecting cattle, buffaloes and sheep, in El-Dakahlyia Governorate." Mansoura Veterinary Medical Journal 20, no. 2 (2019): 70–78. http://dx.doi.org/10.35943/mvmj.2019.22.107.

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In a 2-year survey of tumors occurring in ruminants reared in El-Dakahlyia Governorate, Egypt during the period from October 2016 to October 2018. 66 tumor masses were collected: 60 from cattle, 2 from buffaloes and 4 from sheep. According to histopathology of cattle tumors, 15 neoplasms were diagnosed as cutaneous papilloma, 5 neoplasms were diagnosed as cutaneous fibropapillomas, 25 neoplasms were diagnosed as squamous-cell carcinoma (SCC) of the eye; 8 neoplasms were diagnosed as SCC of perineum, 1 neoplasm was diagnosed as SCC in skin of muzzle, 2 neoplasms were diagnosed as epulis in dent
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Chundupalle, Sashidhar, Nirmala Seeri, Sudarsana Reddy Veera, and Venkata Ramana Nelluri. "Strength and durability characteristics of self compacting concrete (SCC) with recycled aggregate and manufactured sand." Acta Polytechnica CTU Proceedings 33 (March 3, 2022): 92–97. http://dx.doi.org/10.14311/app.2022.33.0092.

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The investigations on self compacting concrete (SCC) with recycled coarse aggregate and Manufactured sand (M-Sand) were performed in this current study. The SCC mixtures were produced with the recycled coarse aggregate of proportions of 0 to 100% with step increment of 25% with a ratio of water binder at 0.36. In addition, the mixtures were also prepared by mixing it with M-Sand. The feasibility of utilizing the recycled coarse aggregate in SCC was evaluated through strength an durability studies. The obtained results demonstrated that the SCC produced from these materials can be effectively r
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22

Liu, Hong Yan, and Jin Gang Qi. "The Effect of Mixture Parameter on the Properties of SCC." Advanced Materials Research 299-300 (July 2011): 355–58. http://dx.doi.org/10.4028/www.scientific.net/amr.299-300.355.

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It is not difficult to prepare self-compacting concrete (SCC) in laboratory now. The problem researchers faced is how SCC can be popularized in civil engineering. A modified densification mixture design algorithm (DMDA) is used in this study to prepare the control mixture. And on the basis of the system analysis for exist studies, 6 factors are chosen as experimental factor and 25 experiments are designed by orthogonal design experiment method. The results analysis indicates that only 3 factors are significant on SCC and their recommend value is obtained respectively. It may shed light on the
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Jin, Xin, Guanhai Dai, Liyang Xuan, Meng Zhang, Huifang Jiang, and Yang Sui. "Effects of Sodium Chlorophyllin Copper on APO-1 Expression in Bone Marrow Mesenchymal Stem Cells of Rats with Aplastic Anaemia." Journal of Immunology Research 2022 (April 6, 2022): 1–10. http://dx.doi.org/10.1155/2022/6792866.

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Background. Aplastic anaemia (AA) is a highly prevalent blood disorder in the East and Southeast Asian countries, and a proportion of the patients is poorly treated with immunosuppressive agents. This study is aimed at exploring the effects of sodium copper chlorophyllin (SCC) on rats with AA and at providing the theoretical basis for the treatment of AA using traditional Chinese medicine. Methods. A rat model of AA was induced by combining 5-fluorouracil with busulfan, and different groups were treated with 25 mg/kg cyclosporin A (CsA) and low-, medium-, and high-dose SCC (25-, 50-, and 100-m
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24

Chao, Zhang, Huang Huan, Xiao Li, Yang Fan, Zhang Yuqi, and Liu Jie. "Stress corrosion cracking behaviors of carbon steel in liquid ammonia." Materials Research Express 11, no. 8 (2024): 085802. http://dx.doi.org/10.1088/2053-1591/ad6ef1.

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Abstract As a carbon-free hydrogen-rich energy carrier, ammonia has gained increasing attention and application in the context of carbon peaking and carbon neutrality. This study evaluated the stress corrosion cracking (SCC) sensitivity of four target materials, A516-70, 16MnDR, 15MnNiDR, and Q370DR, in a liquid ammonia environment at 25 °C and 1.03 MPa by slow stress rate tests to determine their SCC sensitivity index. The microstructure, grain size, misorientation, hardness, strength, and micro-fracture morphology of these materials were compared to analyze the SCC mechanism. The results sho
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25

Simons, Andrean L., Arlene D. Parsons, Katherine A. Foster, Kevin P. Orcutt, Melissa A. Fath, and Douglas R. Spitz. "Inhibition of Glutathione and Thioredoxin Metabolism Enhances Sensitivity to Perifosine in Head and Neck Cancer Cells." Journal of Oncology 2009 (2009): 1–10. http://dx.doi.org/10.1155/2009/519563.

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The hypothesis that the Akt inhibitor, perifosine (PER), combined with inhibitors of glutathione (GSH) and thioredoxin (Trx) metabolism will induce cytotoxicity via metabolic oxidative stress in human head and neck cancer (HNSCC) cells was tested. PER induced increases in glutathione disulfide (%GSSG) in FaDu, Cal-27, and SCC-25 HNSCCs as well as causing significant clonogenic cell killing in FaDu and Cal-27, which was suppressed by simultaneous treatment with N-acetylcysteine (NAC). An inhibitor of GSH synthesis, buthionine sulfoximine (BSO), sensitized Cal-27 and SCC-25 cells to PER-induced
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26

Ezhilarasan, Devaraj, Thangavelu Lakshmi, Upendra Nagaich, and Rajagopal Vijayaragavan. "Acacia catechu ethanolic seed extract triggers apoptosis of SCC-25 cells." Pharmacognosy Magazine 13, no. 51 (2017): 405. http://dx.doi.org/10.4103/pm.pm_458_16.

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27

Bass, Gary Alan, Heidi Furlong, Katie E. O'Sullivan, Thomas P. J. Hennessy, and Thomas Noel Walsh. "Effect of chemoradiotherapy, with adjuvant surgery for local control, on survival in AC and SCC of the esophagus." Journal of Clinical Oncology 32, no. 3_suppl (2014): 81. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.81.

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81 Background: Esophageal cancer usually presents with systemic disease, necessitating systemic therapy. Neo-adjuvant chemoradiotherapy improves short-term survival, but its long-term impact is disputed because of limited accrual, treatment-protocol heterogeneity and a short follow-up of randomised trials. Aims:Long-term results of 2 simultaneous RCTs comparing neo-adjuvant chemo-radiotherapy and surgery (MMT) with surgical monotherapy were examined, and the response of AC (AC) and SCC (SCC) to identical regimens compared. Methods: Between 1990 and 1997, two RCTs were undertaken on 211 patient
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Tamaru, Yuzuru, Shiro Oka, Shinji Tanaka, et al. "Early Squamous Cell Carcinoma of the Anal Canal Resected by Endoscopic Submucosal Dissection." Case Reports in Gastroenterology 9, no. 1 (2015): 120–25. http://dx.doi.org/10.1159/000382074.

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The standard treatment approach for squamous cell carcinoma (SCC) of the anal canal includes abdominoperineal resection and chemoradiotherapy. However, there are currently very few reports of early SCC of the anal canal resected by endoscopic submucosal dissection (ESD). We report 2 rare cases of SCC of the anal canal resected by ESD. In case 1, a 66-year-old woman underwent a colonoscopy due to blood in her stool, and an elevated lesion, 15 mm in size, was identified from the rectum to the dentate line of the anal canal on internal hemorrhoids. The lesion was diagnosed as an early SCC of the
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Ayuba, S., O. A. Uche, S. Haruna, and A. Mohammed. "Durability properties of cement – saw dust ash (SDA) blended self compacting concrete (SCC)." Nigerian Journal of Technology 41, no. 2 (2022): 212–21. http://dx.doi.org/10.4314/njt.v41i2.2.

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This paper report the durability properties of self-compacting concrete (SCC) modified with Saw dust ash (SDA) exposed to an aggressive media. Saw dust ash (SDA) was used to partially replace OPC in SCC at 0 - 30%. A number of trials mixes were conducted to obtain grade 40 SCC, with a suitable mix proportion varied at 5, 10, 15, 20, 25 and 30 % by weight of the binder as OPC replacement in SCC. Constant water to binder ratio of 0.37 with water reducing admixtures was used in all the mixtures. The research reveals that SDA enhanced the resistance of SCC against Na2SO4 attack at 5% replacement b
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Park, Jinyoung, Yoon-Seo Jang, Jeong-Hae Choi, et al. "Anticancer Efficacy of Nonthermal Plasma Therapy Combined with PD-L1 Antibody Conjugated Gold Nanoparticles on Oral Squamous Cell Carcinoma." Applied Sciences 11, no. 10 (2021): 4559. http://dx.doi.org/10.3390/app11104559.

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Combination therapies for the treatment of oral squamous cell carcinoma have been studied extensively and represent a synergistic approach with better outcomes than monotherapy. In this study, a novel combination therapy was investigated using gold nanoparticles (GNP) conjugated to programmed cell death protein ligand 1 (PD-L1) antibodies and nonthermal plasma (NTP). The present study describes the effectiveness of NTP using PD-L1 antibody conjugated to GNP in PD-L1 expressing SCC-25 cells, an oral squamous cell carcinoma line. Immunocytochemistry revealed higher levels of PD-L1 expression and
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31

Mačuhová, Lucia, Vladimí­r Tančin, Juliana Mačuhová, et al. "Effect of somatic cell count on milkability and milk composition of ewes." Potravinarstvo Slovak Journal of Food Sciences 14 (October 28, 2020): 1035–41. http://dx.doi.org/10.5219/1411.

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The trial aimed to study the effect of somatic cell count, breed, milk flow type, and parity on the milkability and milk composition of ewes. The flock consists of purebred Lacaune ewes (LC; n = 29) and crossbreds ewes of Improved Valachian (IV x LC; n = 35) and Tsigai (TS x LC; n = 37) with LC (with a genetic portion of Lacaune 25 and 50%). Ewes were assigned according to somatic cell count (SCC) to one of the following three groups: SCC ≤300,000 cells per mL (SCC Group 300,000), SCC between 300,000 and 1000,000 cells per mL (SCC Group 300,000 – 1000,000), SCC ≥1000,000 cells per mL (SCC Grou
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Leibova, Victoria Borisovna, Marina Vladimirovna Pozovnikova, Olga Vasilievna Tulinova, and Elena Anatolievna Romanova. "The content of somatic cells in goat milk during the breeding and nonbreeding seasons." Agrarian Scientific Journal, no. 12 (December 27, 2023): 106–10. http://dx.doi.org/10.28983/asj.y2023i12pp106-110.

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The somatic cell count (SCC) is considered to be an indirect indicator of the hygienic quality of milk, but the content of somatic cells in goat milk may be due to a number of factors unrelated to intramammary infection. The purpose of our study was to determine the SCC for 5-26 weeks of lactation in Saanen goats of the second lactation in connection with milk yield, the mass fraction of lactose in milk (MFL) and taking into account the breeding season. The analyzed group was formed from 22 females of spring lambing (April). The results of our study showed that at 5-18 weeks lactation, before
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Dinesh, A., D. Suji, and Moorthi Pichumani. "Concurrent Prospects to Develop Activated Charcoal Reinforced Self-Sensing Cement Composites for Structural Health Monitoring Applications." Structural Control and Health Monitoring 2023 (March 7, 2023): 1–19. http://dx.doi.org/10.1155/2023/9731995.

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This research examines the electromechanical characteristics of self-sensing cement composite (SCC) containing activated charcoal (AC) at various concentrations (5%, 10%, 15%, 20%, and 25%). The developed composite is placed in various zones in the beam to monitor beam behaviour, as well as in the column center to monitor column deflection. The research reveals that AC reduced the compressive strength and resistivity of cement composites by generating local hydration and carbon accumulation. The performance index approach optimizes AC concentrations at 25% and 20% without and with 10% silica f
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Stephen, Josena K., Kang Mei Chen, Veena Shah, et al. "Consistent DNA Hypermethylation Patterns in Laryngeal Papillomas." International Journal of Head and Neck Surgery 1, no. 2 (2010): 69–77. http://dx.doi.org/10.5005/jp-journals-10001-1013.

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Abstract Introduction This study examined the contribution of promoter hypermethylation to the pathogenesis of respiratory papillomatosis (RP), including recurrences (RRP) and progression to squamous cell carcinoma (SSC). Materials and methods A retrospective cohort of 25 laryngeal papilloma cases included 21 RRP, two of which progressed to SCC. Aberrant methylation status was determined using the multigene (22 tumor suppressor genes) methylation-specific multiplex ligationdependent probe amplification assay and confirmed using methylation specific PCR. Results Twenty genes had altered DNA met
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Chou, C. H., and J. D. Walters. "Clarithromycin Transport by Gingival Fibroblasts and Epithelial Cells." Journal of Dental Research 87, no. 8 (2008): 777–81. http://dx.doi.org/10.1177/154405910808700812.

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Macrolide antibiotics penetrate cells, but the mechanism by which this occurs is unclear. The objective of this study was to characterize the mechanisms of clarithromycin uptake by gingival fibroblasts and oral epithelium. Cultured human gingival fibroblasts and SCC-25 cells were incubated with [3H]-clarithromycin. We assayed clarithromycin transport by measuring cell-associated radioactivity over time. Fibroblasts and epithelial cells rapidly accumulated clarithromycin, attaining steady-state intracellular concentrations within 15 minutes. Incubation in medium containing 2 μg/mL clarithromyci
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El-Gehani, Faraj, Arunee Dechaphunkul, Muna Kamal, et al. "Small cell carcinoma of the genitourinary tract: A 10-year single institution experience." Journal of Clinical Oncology 30, no. 5_suppl (2012): 312. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.312.

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312 Background: Small cell carcinoma (SCC) of the genitourinary (GU) tract is rare and there is no standard treatment strategy for managing these patients. The objective of this study is to report the clinical experience and management of patients with SCC of the GU tract, treated in the Cross Cancer Institute, Edmonton, AB, Canada from 1999 to 2009. Methods: A retrospective chart review of all patients diagnosed with SCC of the GU tract between 1999 to 2009 was undertaken. Data was collected on demographics, clinical and pathological characteristics, and patient outcomes. Results: Fifty-eight
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Tang, Wai Ching. "Fresh Properties of Self-Compacting Concrete with Coarse Recycled Aggregate." Advanced Materials Research 602-604 (December 2012): 938–42. http://dx.doi.org/10.4028/www.scientific.net/amr.602-604.938.

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In this paper, the fresh properties of self-compacting concrete (SCC) using recycled coarse aggregate (RCA) were evaluated. Five types of SCC mixtures were made, where the percentage of substitution of natural coarse aggregate by RCA was 0, 25, 50, 75 and 100%. The cement content, water to binder (W/B) ratio and Superplasticizer dosage were kept the same for all mixes. The effects of RCA on the key fresh properties such as filling ability, passing ability, and segregation resistance of SCC were investigated by conducting several fresh concrete tests included slump-flow, L-box, and sieve stabil
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Olshinka, Asaf, Dean Ad-El, Elena Didkovski, et al. "Diffusion Reflection Measurements of Antibodies Conjugated to Gold Nanoparticles as a Method to Identify Cutaneous Squamous Cell Carcinoma Borders." Materials 13, no. 2 (2020): 447. http://dx.doi.org/10.3390/ma13020447.

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Diffusion reflectance spectroscopy measurements targeted with gold nanoparticles (GNPs) can identify residual cutaneous squamous cell carcinoma (SCC) in excision borders. Human SCC specimens were stained with hematoxylin and eosin to identify tumor borders, and reflected onto an unstained deparaffinized section. Diffusion reflection of three sites (normal and SCC) were measured before and after GNPs targeting. Hyperspectral imaging showed a mean of 2.5 sites with tumor per specimen and 1.2 tumor-free (p &lt; 0.05, t-test). GNPs were detected in 25/30 tumor sites (sensitivity 83.3%, false-negat
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Gu, Tiantian, Yongchao Wang, Li Wang, Enyang Hao, Chenyang Wang, and Muhan Xie. "Quantifying Residents’ Perceptions of Smart Community Construction through a Hybrid EWM-PROMETHEE II Method: A Case Study of Shenzhen, China." Land 13, no. 8 (2024): 1197. http://dx.doi.org/10.3390/land13081197.

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Smart community construction (SCC) is pivotal for urban modernization, yet extant research often neglects the residents’ perceptions of these initiatives, focusing predominantly on technological advancements. A hybrid evaluation method integrating the Entropy Weight Method (EWM) and PROMETHEE II was developed to quantify residents’ perceptions of SCC. Through the literature review and expert interview, the evaluation indicators for residents’ perceptions of the SCC were identified, leading to the development of an evaluation indicator system consisting of 5 dimensions and 25 indicators. The hy
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Mrode, R. A., and G. J. T. Swanson. "Association between Somatic Cell Count progeny tests in the United States of America (USA), The Netherlands and the United Kingdom (UK)." Proceedings of the British Society of Animal Science 1997 (1997): 25. http://dx.doi.org/10.1017/s1752756200594666.

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Mastitis remains a costly health problem to dairy farmers despite a significant reduction in both clinical and sub-clinical mastitis over the last 25 years. This reduction has been due predominantly to the success of management control programmes. The continuing losses have raised the interest in breeding as a means to reduce mastitis incidence. Somatic Cell Counts (SCC) have been used since 1977 as an indirect means of monitoring mastitis within dairy herds. Since 1991 an optional individual cell count service has been offered by Milk Recording Organisations in the UK. The result is that 0.80
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Karem Abd, Mohammed, and Zuhair Dhaher Habeeb. "Effect Of Specimen Size and Shape on Compressive Strength of Self-Compacting Concrete." Diyala Journal of Engineering Sciences 7, no. 2 (2014): 16–29. http://dx.doi.org/10.24237/djes.2014.07202.

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This study aims to show the effect of specimen size and shape on compressive strength of self-compacting concrete (SCC). The work is divided into two parts, the first was to designed Normal Concrete (NC), High Strength Concrete (HSC) and Self Compacting Concrete (SCC) of strength between (25-70) MPa. from locally available materials. The values percent of cylinder to cube strength were between (0.86-0.9), (0.94-0.96), (0.96-0.99) of NC, HSC and SCC respectively.The second is to investigate the effect of specimen size on compressive strength, the values of correction factor of cube specimens (1
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Du, Hao-Fei, Jia-Wei Wu, Yu-Shan Zhu, et al. "Fucoxanthin Induces Ferroptosis in Cancer Cells via Downregulation of the Nrf2/HO−1/GPX4 Pathway." Molecules 29, no. 12 (2024): 2832. http://dx.doi.org/10.3390/molecules29122832.

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This study investigated the mechanism by which fucoxanthin acts as a novel ferroptosis inducer to inhibit tongue cancer. The MTT assay was used to detect the inhibitory effects of fucoxanthin on SCC−25 human tongue squamous carcinoma cells. The levels of reactive oxygen species (ROS), mitochondrial membrane potential (MMP), glutathione (GSH), superoxide dismutase (SOD), malondialdehyde (MDA), and total iron were measured. Reverse transcription–quantitative polymerase chain reaction (RT−qPCR) and Western blotting were used to assess glutathione peroxidase 4 (GPX4), nuclear factor erythroid 2−re
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Maclean, Gael M., and David J. Coleman. "Three Fatal Cases of Squamous Cell Carcinoma Arising in Chronic Perineal Hidradenitis Suppurativa." Annals of The Royal College of Surgeons of England 89, no. 7 (2007): 709–12. http://dx.doi.org/10.1308/003588407x209392.

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INTRODUCTION Hidradenitis suppurativa (HS) is a chronic, inflammatory and suppurative disorder of skin bearing apocrine glands. The most severe complication is squamous cell carcinoma (SCC) and we here present three cases, all of which proved fatal, and review the past 40 years of published cases. PATIENTS AND METHODS Three advanced cases of SCC arising in chronic HS have been referred for reconstructive surgery over the past 8 years. Another 28 cases published over the past 40 years were identified using a Medline search (search items in combination: hidradenitis, squamous, carcinoma). RESULT
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Ayuba, Solomon. "Fresh And Microstructural Properties Of Saw Dust Ash (SDA) Admixed With Millet Husk Ash (MHA) In Self Compacting Concrete (SCC)." Platform : A Journal of Engineering 7, no. 3 (2023): 2. http://dx.doi.org/10.61762/pajevol7iss3art24132.

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The quest to mitigate the high cost and the environmental hazard associated with cement production has increased globally. Saw dust ash (SDA) and Millet husk ash (MHA)were obtained by burning at temperatures between 600ºC-650ºC and used at a varied mix proportion of 0%, 5%, 10%, 15%, 20%, 25%, and 30%. SDA and MHA were employed to partially replace Ordinary Portland cement (OPC) in the production of grade 40 self-compacting concrete (SCC). To enhance the strength properties of SDA-SCC, an optimum dose of MHA was incorporated to produce SDA-MHA-SCC. Several trial mixes per standard specificatio
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Zheng, Shiqi, Qing Liu, Fengxia Han, Shan Liu, Tong Han, and Hao Yan. "Basic Mechanical Properties of Self-Compacting Concrete Prepared with Aeolian Sand and Recycled Coarse Aggregate." Buildings 14, no. 9 (2024): 2949. http://dx.doi.org/10.3390/buildings14092949.

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To protect the environment and reduce the consumption of natural resources, this study investigated the performance of self-compacting concrete (SCC) utilizing aeolian sand (AS) as a replacement for fine aggregate and recycled coarse aggregate (RCA) as a replacement for natural coarse aggregate. Twelve mixing ratios were prepared, with AS replacement ratios at 0, 20%, 40%, and 60% and RCA replacement ratios at 0, 25%, and 50%. The evaluation primarily focused on workability, uniaxial compressive strength, split tensile strength, stress–strain curve, modulus of elasticity, and axial compressive
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Carmona-Hernandez, Andrés, A. Contreras, Jorge Uruchurtu Chavarín, Jose Gonzalo Gonzalez Rodriguez, Ricardo Orozco Cruz, and R. Galván Martínez. "Electrochemical Noise of SCC Inhibition of a Supermartensitic Stainless Steel in Sour Solution." ECS Transactions 110, no. 1 (2023): 29–37. http://dx.doi.org/10.1149/11001.0029ecst.

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In this work, the inhibition effect of a non-ionic gemini surfactant, named bis(2-((2-palmitoamidoethyl)amino)ethyl)1H-imidazole4,5-dicarboxylate, on the stress corrosion cracking (SCC) behavior of a supermartensitic stainless steel (SMSS) was studied in sour environment. The slow strain rate stress tests (SSRT) results and fractographic analysis revealed that the corrosion inhibitor was able to inhibit the SCC process using a concentration above than 5ppm. At concentrations of 0 and 5 ppm, the steel showed a brittle fracture with susceptibility to SCC, whereas at concentrations of 25 and 100
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Anari, Fern, Benjamin Miron, Donald Henson, et al. "Non-urothelial bladder cancer: Genomic alterations and patient outcomes." Journal of Clinical Oncology 37, no. 7_suppl (2019): 399. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.399.

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399 Background: Adenocarcinoma (ADA) and squamous cell carcinoma (SCC) are rare, aggressive subtypes of bladder cancer, for which no clear standard of care exists. We report on survival of pts with ADA and SCC and identify potential therapeutic targets using molecular profiling via next generation sequencing (NGS). Methods: Survival trends, demographics, pt characteristics were obtained from the Surveillance, Epidemiology, and End Results (SEER) Database. In a separate cohort, NGS results from 72 specimens (50% metastatic) were also analyzed, using either a hotspot 47 gene panel or a 592 gene
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Al - Abdalay, Nadia M. "INFLUNCE OF WATER CURING TEMPERATURE ON SOME MECHANICAL PROPERTIES OF SCC PRODUCED FROM RECYCLED AGGREGATES." Kufa Journal of Engineering 5, no. 2 (2014): 117–38. http://dx.doi.org/10.30572/2018/kje/521323.

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The utilization of recycled aggregates can minimize environmental impact and slow the huge consumption of natural resources used for concrete applications. However, recycled aggregates are not suitable for use in the production of High Performance Concrete (HPC) due to their relatively high absorption capacity, unstable properties and recycled aggregates' weaker strength. Such inadequacies can be overcome through carefully examining the characteristics of recycled aggregates and then adopting proper mixture proportions. The mechanical properties of self compacting concrete (SCC) are well under
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Haas, Y. de, H. W. Barkema, Y. H. Schukken, and R. F. Veerkamp. "Genetic associations for pathogen-specific clinical mastitis and patterns of peaks in somatic cell count." Animal Science 77, no. 2 (2003): 187–95. http://dx.doi.org/10.1017/s1357729800058926.

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AbstractGenetic associations were estimated between pathogen-specific cases of clinical mastitis (CM), lactational average somatic cell score (LACSCS), and patterns of peaks in somatic cell count (SCC) which were based on deviations from the typical lactation curve for SCC. The dataset contained test-day records on SCC in 94 781 lactations of 25 416 cows of different parities. Out of these 94 781 lactations, 41 828 lactations had recordings on occurrence of pathogen-specific CM and on SCC, and 52 953 lactations had recordings on SCC only. A total of 5 324 lactations with cases of CM were recor
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Mostafa, Rahma, Ehab Abd-ElHamid, Amr El-Bolok, Enas ELdin, and Safaa Tohamy. "Possible Effect of Pyrogallol on Tongue Squamous Cell Carcinoma SCC-25 Cells." Minia Journal of Medical Research 32, no. 2 (2021): 77–87. http://dx.doi.org/10.21608/mjmr.2021.231548.

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