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Journal articles on the topic 'SCIP'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 March 2023

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1

Aschtgen, Marie-Stéphanie, Christophe S. Bernard, Sophie De Bentzmann, Roland Lloubès, and Eric Cascales. "SciN Is an Outer Membrane Lipoprotein Required for Type VI Secretion in Enteroaggregative Escherichia coli." Journal of Bacteriology 190, no. 22 (September 19, 2008): 7523–31. http://dx.doi.org/10.1128/jb.00945-08.

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ABSTRACT Enteroaggregative Escherichia coli (EAEC) is a pathogen implicated in several infant diarrhea or diarrheal outbreaks in areas of endemicity. Although multiple genes involved in EAEC pathogenesis have been identified, the overall mechanism of virulence is not well understood. Recently, a novel secretion system, called type VI secretion (T6S) system (T6SS), has been identified in EAEC and most animal or plant gram-negative pathogens. T6SSs are multicomponent cell envelope machines responsible for the secretion of at least two putative substrates, Hcp and VgrG. In EAEC, two copies of T6S gene clusters, called sci-1 and sci-2, are present on the pheU pathogenicity island. In this study, we focused our work on the sci-1 gene cluster. The Sci-1 apparatus is probably composed of all, or a subset of, the 21 gene products encoded on the cluster. Among these subunits, some are shared by all T6SSs identified to date, including a ClpV-type AAA+ ATPase (SciG) and an IcmF (SciS) and an IcmH (SciP) homologue, as well as a putative lipoprotein (SciN). In this study, we demonstrate that sciN is a critical gene necessary for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation. We further show that SciN is a lipoprotein, as shown by the inhibition of its processing by globomycin and in vivo labeling with [3H]palmitic acid. SciN is tethered to the outer membrane and exposed in the periplasm. Sequestration of SciN at the inner membrane by targeting the +2 residue responsible for lipoprotein localization (Gly2Asp) fails to complement an sciN mutant for SciD secretion and biofilm formation. Together, these results support a model in which SciN is an outer membrane lipoprotein exposed in the periplasm and essential for the Sci-1 apparatus function.

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2

Yoshimatsu, Hidehiko, Ryo Karakawa, Yuma Fuse, Akitatsu Hayashi, and Tomoyuki Yano. "Superficial Circumflex Iliac Artery Perforator Flap Elevation Using Preoperative High-Resolution Ultrasonography for Vessel Mapping and Flap Design." Journal of Reconstructive Microsurgery 38, no. 03 (October 23, 2021): 217–20. http://dx.doi.org/10.1055/s-0041-1736317.

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Abstract Background The superficial circumflex iliac artery (SCIA) perforator (SCIP) flap has gained acceptance among reconstructive microsurgeons, the minimal donor site morbidity being its greatest advantage. The purpose of this article is to introduce the use of preoperative ultrasonography to facilitate elevation and to avoid postoperative complications of the SCIP flap. Methods Preoperative mapping of the SCIA and the superficial circumflex iliac vein (SCIV) using a high-resolution ultrasound system were performed in patients undergoing reconstruction using a free SCIP flap. The skin paddle was designed placing the SCIA and the SCIV in the middle of the flap. Results Preoperatively marked SCIA and SCIV were found intraoperatively in all cases. The skin paddle design for sufficient arterial inflow and venous drainage resulted in no postoperative flap complications. Conclusion The use of a preoperative high-resolution ultrasound system significantly facilitates elevation of the SCIP flap, notably via the following 2 points: 1) pedicle can always be found under the markings made with preoperative ultrasonography, 2) satisfactory perfusion of the flap can be guaranteed via a safe flap design that includes preoperatively marked vessels within the skin paddle.

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Schiltz, Daniel, Jasmin Lenhard, Silvan Klein, Alexandra Anker, Daniel Lonic, Paul I. Heidekrueger, Lukas Prantl, Ernst-Michael Jung, Natascha Platz Batista Da Silva, and Andreas Kehrer. "Do-It-Yourself Preoperative High-Resolution Ultrasound-Guided Flap Design of the Superficial Circumflex Iliac Artery Perforator Flap (SCIP)." Journal of Clinical Medicine 10, no. 11 (May 30, 2021): 2427. http://dx.doi.org/10.3390/jcm10112427.

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The superficial circumflex iliac artery perforator (SCIP) flap is a well-documented, thin, free tissue flap with a minimal donor site morbidity, and has the potential to become the new method for resurfacing moderate-size skin defects. The aim of this study is to describe an easy, reliable, systematic, and standardized approach for preoperative SCIP flap design and perforator characterization, using color-coded duplex sonography (CCDS). A list of customized settings and a straightforward algorithm are presented, which are easily applied by an operator with minimal experience. Specific settings for SCIP flap perforator evaluation were investigated and tested on 12 patients. Deep and superficial superficial circumflex iliac artery (SCIA) branches, along with their corresponding perforators and cutaneous veins, were marked individually with a permanent marker and the anatomy was verified intraoperatively. From this, a simplified procedure for preoperative flap design of the SCIP flap was developed. Branches could be localized and evaluated in all patients. A preoperative structured procedure for ultrasonically guided flap design of the SCIP flap is described. A 100% correlation between the number and emergence points of the branches detected by preoperative CCDS mapping and the intraoperative anatomy was found.

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4

Hosking, George. "SCIP meetings." Competitive Intelligence Review 3, no. 2 (1992): 54. http://dx.doi.org/10.1002/cir.3880030220.

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5

Scott, Tracey. "Global SCIP." Competitive Intelligence Review 7, no. 2 (1996): 1. http://dx.doi.org/10.1002/cir.3880070202.

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6

Battisti, Michèle. "Conférence SCIP?France." Documentaliste-Sciences de l'Information 41, no. 3 (2004): 203. http://dx.doi.org/10.3917/docsi.413.0203.

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7

Drake, Kirsten. "SCIP core measures." Nursing Management (Springhouse) 42, no. 5 (May 2011): 24–30. http://dx.doi.org/10.1097/01.numa.0000396344.54830.0d.

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8

&NA;. "SCIP core measures." Nursing Management (Springhouse) 42, no. 5 (May 2011): 30–31. http://dx.doi.org/10.1097/01.numa.0000397996.63175.fa.

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9

Pearson, John. "SCIP Europe news." Competitive Intelligence Review 2, no. 3 (1992): 24–25. http://dx.doi.org/10.1002/cir.3880020311.

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10

Huntington, Ciara R., Melissa Strayer, Toan Huynh, and John M. Green. "A Multidisciplinary Approach to Improving SCIP Compliance." American Surgeon 81, no. 7 (July 2015): 687–92. http://dx.doi.org/10.1177/000313481508100717.

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The Surgical Care Improvement Project (SCIP) is a national program aimed at reducing perioperative complications and is a quality benchmark metric for Centers for Medicare and Medicaid Services. This study evaluates whether a multidisciplinary program improved an institution's compliance with SCIP measures. Analysis of the facility's performance data identified three key areas of SCIP noncompliance: 1) timely discontinuation of perioperative antibiotics and urinary catheters, 2) initiation of venous thromboembolism prophylaxis, and 3) perioperative beta blocker administration. Multidisciplinary teams collaborated with providers and department chairs in reviewing and enable SCIP compliance. Anesthesia staff managed preoperative antibiotics. SCIP-compliant order sets, venous thromboembolism pop-up alerts, and progress note templates were added to the electronic medical record. Standardized education was provided to explain SCIP requirements, review noncompliant cases, and update teams on SCIP performance. Data were captured from January 2009 to March 2014. Ten SCIP fallouts were reported for general surgery specialties in January 2013, when the SCIP compliance project launched. Specifically, colon-related surgery achieved 100 per cent compliance. Six months after implementation, overall SCIP compliance at our institution improved by 65 per cent (from 90.7–98.6% compliance).

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11

Khitab, Anwar. "Finite Element Analysis of Structural Concrete Insulated Panels Subjected to Dynamic Loadings." Civil Engineering Beyond Limits 1, no. 2 (April 1, 2020): 31–37. http://dx.doi.org/10.36937/cebel.2020.002.005.

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Human population is growing around the world day by day, necessitating highly sustainable and energy efficient building systems. In conventional building systems, significant amount of energy is consumed for providing thermal comfort to the occupants. Materials used for thermal insulation not only increase the cost of the buildings but also increase the dead weight. Structural concrete insulated panel system (SCIP) provide thermally efficient, light weight, and low-cost solution as compared to the conventional systems. SCIP system is new innovation in which, insulation material is placed between two layers of concrete. Due to low weight, it can be easily handled and transported to project sites. In present research, the performance of SCIP walls in a typical school double story building is examined by three-dimensional finite element analysis, using SAP2000. The response is evaluated by varying the thickness of the insulation layer in terms of safety and serviceability. The results show that the buildings incorporating SCIPs are capable to withstand high dynamic and earthquake loads and are significantly economical as compared to the conventional building systems.

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12

Garcia, Nicole, Sandy Fogel, Christopher Baker, Stephen Remine, and Jim Jones. "Should Compliance with the Surgical Care Improvement Project (SCIP) Process Measures Determine Medicare and Medicaid Reimbursement Rates?" American Surgeon 78, no. 6 (June 2012): 653–56. http://dx.doi.org/10.1177/000313481207800617.

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The Surgical Care Improvement Project (SCIP) is aproject that focuses on improving surgical care by reducing surgical morbidity and mortality by 25 per cent by 2010. Starting in 2011, SCIP compliance affects Medicare and Medicaid reimbursement rates. Although SCIP reinforces better practices in surgical care, does compliance with SCIP measures actually result in a decrease in surgical morbidity and mortality? This study examined compliance with the SCIP surgical site infection (SSI) module (prophylactic antibiotic received within 1 hour before surgical incision) during 2009 to 2010 (n = 703) to determine whether patients compliant with SCIP data had a correlation with SSI rates as reported by National Surgery Quality Improvement Program (NSQIP) data for the same time period. We found no statistically significant association in patients that have failed SCIP INF1 in the years 2009 to 2010 (n = 43) and the rates of SSI (n = 0) for the same time period. These data suggest that SCIP compliance should not be used to determine Medicare and Medicaid reimbursement rates because there is no correlation between failure of SCIP INF1 and SSI. Instead, further effort should be placed on developing tools designed to acknowledge outcome measures that result in decreased morbidity/mortality and change practices accordingly such as NSQIP.

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13

Fyodorov, D., and E. Deneris. "The POU domain of SCIP/Tst-1/Oct-6 is sufficient for activation of an acetylcholine receptor promoter." Molecular and Cellular Biology 16, no. 9 (September 1996): 5004–14. http://dx.doi.org/10.1128/mcb.16.9.5004.

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In the PC12 neuroendocrine line, the neuronal nicotinic acetylcholine receptor alpha3 gene promoter is activated by SCIP/Tst-1/Oct-6, a POU domain transcription factor proposed to be important for regulating the development of specific neural cell populations. In this study, we have investigated the SCIP polypeptide domains involved in alpha3 promoter activation. The characteristics of activation by a chimeric effector in which the GAL4 DNA binding domain was substituted for the SCIP POU domain were dramatically different from those of wild-type SCIP. At low effector masses, the chimeric polypeptide weakly activated alpha3 in a GAL4 binding-site-dependent manner but then squelched transcription at higher masses. In contrast, wild-type SCIP activation was not modulated by the presence of multimerized SCIP binding sites, and squelching was not observed. Analysis of wild-type SCIP truncations revealed that deletion of the previously characterized SCIP amino-terminal activation domain did not destroy activity of the factor. Surprisingly, a truncation expressing nothing more than the POU domain was nearly as active as wild-type SCIP. Moreover, cotransfection of a GAL4-VP16 effector with an effector expressing just the SCIP POU domain resulted in synergistic activation of the promoter. Synergistic activation did not depend on an Sp1 motif that is the only functional alpha3 cis element outside the transcription start site region. Our results show that the DNA binding domain of a POU factor is capable of transcriptional activation probably through protein-protein interactions with components of the basal transcription complex.

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14

Collarini, E. J., R. Kuhn, C. J. Marshall, E. S. Monuki, G. Lemke, and W. D. Richardson. "Down-regulation of the POU transcription factor SCIP is an early event in oligodendrocyte differentiation in vitro." Development 116, no. 1 (September 1, 1992): 193–200. http://dx.doi.org/10.1242/dev.116.1.193.

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The POU-domain transcription factor SCIP (also known as Tst-1) has been implicated in the development of Schwann cells, the myelinating cells of the peripheral nervous system (PNS). We have investigated the possibility that SCIP also might play a role in the development of oligodendrocytes, the myelinating cells of the central nervous system (CNS). We purified oligodendrocyte precursors (O-2A progenitors) by immunoselection and cultured them in the presence of platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF), which together keep O-2A progenitors proliferating and prevent oligodendrocyte differentiation. Under these culture conditions, O-2A progenitors expressed high levels of SCIP mRNA and protein, and did not express myelin-specific genes. When oligodendrocyte differentiation was initiated by withdrawing the growth factors, SCIP mRNA was rapidly down-regulated, followed by a decline in SCIP protein and the sequential activation of myelin-specific genes. Rapid down-regulation of SCIP mRNA required continued protein synthesis. In O-2A progenitors that were cultured in the presence of PDGF alone, SCIP expression declined to an intermediate level, and low levels of the myelin gene products were induced. Thus, the level of SCIP expression in O-2A progenitors is inversely related to the level of myelin gene expression, suggesting that SCIP may be involved in the developmental switch from proliferation to differentiation in the oligodendrocyte lineage. When O-2A progenitors are cultured in the presence of 10% fetal calf serum, they differentiate into type-2 astrocytes rather than oligodendrocytes. SCIP mRNA was also down-regulated in type-2 astrocytes, which do not express myelin genes, so down-regulation of SCIP seems to be more closely linked to the cessation of cell proliferation per se than the expression of a particular differentiated phenotype.

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15

Sock, Elisabeth, Janna Enderich, and Michael Wegner. "The J Domain of Papovaviral Large Tumor Antigen Is Required for Synergistic Interaction with the POU-Domain Protein Tst-1/Oct6/SCIP." Molecular and Cellular Biology 19, no. 4 (April 1, 1999): 2455–64. http://dx.doi.org/10.1128/mcb.19.4.2455.

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ABSTRACT Large T antigens from polyomaviruses are multifunctional proteins with roles in transcriptional regulation, viral DNA replication, and cellular transformation. They have been shown to enhance the activity of various cellular transcription factors. In the case of the POU protein Tst-1/Oct6/SCIP, this enhancement involves a direct physical interaction between the POU domain of the transcription factor and the amino-terminal region of large T antigen. Here we have analyzed the structural requirements for synergistic interaction between the two proteins in greater detail. Tst-1/Oct6/SCIP and the related POU protein Brn-1 were both capable of direct physical interaction with large T antigen. Nevertheless, only Tst-1/Oct6/SCIP functioned synergistically with large T antigen. This differential behavior was due to differences in the amino-terminal regions of the proteins, as evident from chimeras between Tst-1/Oct6/SCIP and Brn-1. Synergy was specifically observed for constructs containing the amino-terminal region of Tst-1/Oct6/SCIP. Large T antigen, on the other hand, functioned synergistically with Tst-1/Oct6/SCIP only when the integrity of its J-domain-containing amino terminus was maintained. Mutations that disrupted the J domain concomitantly abolished the ability to enhance the function of Tst-1/Oct6/SCIP. The J domain of T antigen was also responsible for the physical interaction with Tst-1/Oct6/SCIP and could be replaced in this property by other J domains. Intriguingly, a heterologous J domain from a human DnaJ protein partially substituted for the amino terminus of T antigen even with regard to the synergistic enhancement of Tst-1/Oct6/SCIP function. Given the general role of J domains, we propose chaperone activity as the underlying mechanism for synergy between Tst-1/Oct6/SCIP and large T antigens.

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16

Wierman, M. E., X. Xiong, J. K. Kepa, A. J. Spaulding, B. M. Jacobsen, Z. Fang, G. Nilaver, and S. R. Ojeda. "Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: a regulatory mechanism of phenotype expression?" Molecular and Cellular Biology 17, no. 3 (March 1997): 1652–65. http://dx.doi.org/10.1128/mcb.17.3.1652.

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POU domain transcription factors are required for neuropeptide expression in selected subsets of hypothalamic neuroendocrine neurons. We now report that expression of the gonadotropin-releasing hormone (GnRH) gene, which controls sexual development, is regulated by the POU protein SCIP/Oct-6/Tst-1. Reverse transcriptase PCR cloning and RNase protection assays demonstrated the presence of SCIP/Oct-6/Tst-1 mRNA in the GnRH-producing neuronal cell line GT1-7. The physiological relevance of this regulatory activity was suggested by the detection of SCIP/Oct-6/Tst-1 mRNA in a subset of GnRH neurons in the hypothalamus of prepubertal female rats. Coexpression of SCIP/Oct-6/Tst-1 in neuronal cells inhibited rat GnRH (rGnRH) promoter activity via three regions of the proximal rGnRH promoter containing SCIP/Oct-6/Tst-1 binding sites. DNase I footprinting, gel shift assays, and DNA and protein mutagenesis studies indicated that both direct DNA binding and protein-protein interactions are required for SCIP/Oct-6/Tst-1 modulation of GnRH gene expression. Activation of SCIP/Oct-6/Tst-1 expression in terminally differentiated GnRH neurons may be a factor determining the ratio of phenotypically "inactive" versus "active" GnRH neurons during postnatal life.

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17

Monsch, Andreas U., Christina Feldmann, Manfred Berres, Monique Beutler, Andreas Studer, Hannes B. Stähelin, and René Spiegel. "Severe Cognitive Impairment Profile (SCIP)." Zeitschrift für Gerontopsychologie & -psychiatrie 18, no. 2 (January 2005): 57–66. http://dx.doi.org/10.1024/1011-6877.18.2.57.

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Zusammenfassung: Das SCIP wurde in den USA wenige Jahre nach der SIB als neuropsychologische Skala für die Untersuchung kognitiver Funktionen bei schwer Dementen veröffentlicht. Ziel der vorliegenden Untersuchung war die klinische Anwendung und empirische Überprüfung (Objektivität, Reliabilität, Empfindlichkeit im untersten Messbereich kognitiver Leistungen) einer deutschsprachigen Version des SCIP. Untersucht wurden 57 (42 w, 15 m) hospitalisierte, schwer demente Patienten (Alter: 83.0, SD 9.0; MMSE: 5.6, SD 5.3) verschiedener Ätiologie. Das SCIP zeigte eine sehr hohe Inter-Rater-Reliabilität (1.0) und Interne Konsistenz (.96). Die Korrelation mit dem MMSE-Score betrug 0.84, jene mit dem SIB-Score 0.97 (alle p < .001). Im SCIP erreichten 13 von 14 Patienten mit MMSE = 0 messbare Werte. Die deutschsprachige Version des SCIP erfüllt sowohl die Anforderung betr. Empfindlichkeit im untersten Messbereich, wie auch diejenigen der Objektivität und Reliabilität.

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18

Ferchaud, Bernadette. "Journée d'étude SCIP France." Documentaliste-Sciences de l'Information 39, no. 4 (2002): 228. http://dx.doi.org/10.3917/docsi.394.0228.

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19

Ferchaud, Bernadette. "Journée d'étude SCIP ? CCIP." Documentaliste-Sciences de l'Information 39, no. 6 (2002): 318. http://dx.doi.org/10.3917/docsi.396.0318.

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20

Ferchaud, Bernadette. "Journée d'étude SCIP France." Documentaliste-Sciences de l'Information 40, no. 1 (2003): 29. http://dx.doi.org/10.3917/docsi.401.0029.

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21

McCarron, Kim. "Donʼt skip the SCIP!" Nursing Made Incredibly Easy! 12, no. 5 (2014): 15–19. http://dx.doi.org/10.1097/01.nme.0000452688.19763.76.

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22

Barie, Philip S. "SCIP to the Loo?" Surgical Infections 12, no. 3 (June 2011): 161–62. http://dx.doi.org/10.1089/sur.2011.9915.

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23

Booth, Jeffrey. "The SCIP core measures." Nursing Management (Springhouse) 40, no. 3 (March 2009): 10–14. http://dx.doi.org/10.1097/01.numa.0000347405.42707.47.

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24

Pinzur, Michael. "FootForum: DVT and SCIP." Foot & Ankle International 32, no. 9 (September 2011): 923. http://dx.doi.org/10.3113/fai.2011.0923.

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25

Anthony, Jane Kinzler. "SCIP: 1991 membership survey." Competitive Intelligence Review 2, no. 2 (1991): 25–26. http://dx.doi.org/10.1002/cir.3880020212.

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Allgaier, Cyndi. "Scip comes of age." Competitive Intelligence Review 3, no. 3-4 (1992): 65. http://dx.doi.org/10.1002/cir.3880030315.

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27

Gentileschi, Stefano, Maria Servillo, Francesca De Bonis, Roberta Albanese, Valentina Pino, Maria Lucia Mangialardi, Iacopo Valente, et al. "Radioanatomical Study of the Pedicle of the Superficial Circumflex Iliac Perforator Flap." Journal of Reconstructive Microsurgery 35, no. 09 (July 17, 2019): 669–76. http://dx.doi.org/10.1055/s-0039-1693144.

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Background The superficial circumflex iliac perforator (SCIP) flap has many ideal features, such as fast dissection, possibility to harvest thin, pliable, wide skin island, and concealed donor site scar. In spite of these features, its use was limited because of the wide anatomical variation of the pedicle, which is relatively shorter and has a smaller caliber than other more popular perforator flaps. Several names were given to the branches and perforators in the literature, thus adding confusion to the understanding of its anatomy. Methods We performed a surgical and a radioanatomical study of the SCIP pedicles analyzing high-resolution contrast-enhanced computed tomography (CT) scan of 95 groins, with particular attention to the deep branch (DB) of the superficial circumflex iliac artery (SCIA). Twenty-three of these patients were also studied by detecting the surgical anatomy during SCIP flap harvest. We employed a system of coordinates based on the line between pubic tubercle (PT) and anterior superior iliac spine (ASIS) to describe the position of the perforator of the DB. Results We found a 100% correlation between surgical and radiological findings. The length of the DB from the origin to the point in which its perforator pierced the sartorius fascia ranged from 1.6 to 6.5 cm, mean = 3.62 ± 0.92 cm. The distance between the origin of the DB and the inguinal ligament ranged from 1.1 to 7.5 cm, mean = 2.8 ± 1 cm. The perforator of the DB could be found in 91% of the cases within a box of 4 cm × 3 cm drawn caudally to the line joining the PT with the ASIS. This vessel can show a vertical or horizontal course in the subcutaneous layer. Conclusion Our findings confirm other previous studies and add new information about the position and the course of the perforator of the DB of the SCIA. Important features of the SCIP pedicles can be investigated by the color Doppler ultrasound and CT scan.

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Scott, Andrew V., Jerry L. Stonemetz, Jack O. Wasey, Daniel J. Johnson, Richard J. Rivers, Colleen G. Koch, and Steven M. Frank. "Compliance with Surgical Care Improvement Project for Body Temperature Management (SCIP Inf-10) Is Associated with Improved Clinical Outcomes." Anesthesiology 123, no. 1 (July 1, 2015): 116–25. http://dx.doi.org/10.1097/aln.0000000000000681.

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Abstract Background: In an effort to measure and improve the quality of perioperative care, the Surgical Care Improvement Project (SCIP) was introduced in 2003. The SCIP guidelines are evidence-based process measures designed to reduce preventable morbidity, but it remains to be determined whether SCIP-measure compliance is associated with improved outcomes. Methods: The authors retrospectively analyzed the electronic medical record data from 45,304 inpatients at a single institution to assess whether compliance with SCIP Inf-10 (body temperature management) was associated with a reduced incidence of morbidity and mortality. The primary outcomes were hospital-acquired infection and ischemic cardiovascular events. Secondary outcomes were mortality and hospital length of stay. Results: Body temperature on admission to the postoperative care unit was higher in the SCIP-compliant group (36.6° ± 0.5°C; n = 44,064) compared with the SCIP-noncompliant group (35.5° ± 0.5°C; n = 1,240) (P < 0.0001). SCIP compliance was associated with improved outcomes in both nonadjusted and risk-adjusted analyses. SCIP compliance was associated with a reduced incidence of hospital-acquired infection (3,312 [7.5%] vs.160 [12.9%] events; risk-adjusted odds ratio [OR], 0.68; 95% CI, 0.54 to 0.85), ischemic cardiovascular events (602 [1.4%] vs. 38 [3.1%] events; risk-adjusted OR, 0.60; 95% CI, 0.41 to 0.92), and mortality (617 [1.4%] vs. 60 [4.8%] events; risk-adjusted OR, 0.41; 95% CI, 0.29 to 0.58). Median (interquartile range) hospital length of stay was also decreased: 4 (2 to 8) versus 5 (2 to 14) days; P < 0.0001. Conclusion: Compliance with SCIP Inf-10 body temperature management guidelines during surgery is associated with improved clinical outcomes and can be used as a quality measure.

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29

Nahabedian, Maurice Y. "To Scip … or Not to Scip … the Surgical Care Improvement Project Protocol." Plastic and Reconstructive Surgery 130, no. 5 (November 2012): 1161–63. http://dx.doi.org/10.1097/prs.0b013e318267d754.

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30

Halvorson, Eric G., Andrea Bazakas, John L. Clayton, Clara N. Lee, and C. Scott Hultman. "To Scip … or Not to Scip … the Surgical Care Improvement Project Protocol." Plastic and Reconstructive Surgery 132, no. 2 (August 2013): 317e—318e. http://dx.doi.org/10.1097/prs.0b013e3182958d0a.

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31

Zorick, T. S., D. E. Syroid, A. Brown, T. Gridley, and G. Lemke. "Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells." Development 126, no. 7 (April 1, 1999): 1397–406. http://dx.doi.org/10.1242/dev.126.7.1397.

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The transcription factors Krox-20 and SCIP each play important roles in the differentiation of Schwann cells. However, the genes encoding these two proteins exhibit distinct time courses of expression and yield distinct cellular phenotypes upon mutation. SCIP is expressed prior to the initial appearance of Krox-20, and is transient in both the myelinating and non-myelinating Schwann cell lineages; while in contrast, Krox-20 appears approximately 24 hours after SCIP and then only within the myelinating lineage, where its expression is stably maintained into adulthood. Similarly, differentiation of SCIP−/− Schwann cells appears to transiently stall at the promyelinating stage that precedes myelination, whereas Krox-20(−/−) cells are, by morphological criteria, arrested at this stage. These observations led us to examine SCIP regulation and Schwann cell phenotype in Krox-20 mouse mutants. We find that in Krox-20(−/−) Schwann cells, SCIP expression is converted from transient to sustained. We further observe that both Schwann cell proliferation and apoptosis, which are normal features of SCIP+ cells, are also markedly increased late in postnatal development in Krox-20 mutants relative to wild type, and that the levels of cell division and apoptosis are balanced to yield a stable number of Schwann cells within peripheral nerves. These data demonstrate that the loss of Krox-20 in myelinating Schwann cells arrests differentiation at the promyelinating stage, as assessed by SCIP expression, mitotic activity and susceptibility to apoptosis.

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32

Berner, Juan Enrique, Dariush Nikkhah, Jade Zhao, Elena Prousskaia, and Tiew Chong Teo. "The Versatility of the Superficial Circumflex Iliac Artery Perforator Flap: A Single Surgeon's 16-Year Experience for Limb Reconstruction and a Systematic Review." Journal of Reconstructive Microsurgery 36, no. 02 (September 2, 2019): 093–103. http://dx.doi.org/10.1055/s-0039-1695051.

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Background The superficial circumflex iliac artery perforator (SCIP) flap is a versatile option of free tissue transfer for small to large defects. In this study, we examine the advantages of the SCIP flap, its cadaveric anatomy, and clinical subtypes. Methods Ten cadavers were dissected and the corresponding pedicles of the SCIP and groin flaps were identified. A retrospective review of 20 clinical cases of free SCIP flap reconstruction was undertaken. The indication for reconstruction, flap dimensions, and survival were analyzed. A systematic literature review was conducted including articles that have previously reported the use of the SCIP flap. Results The SCIP pedicle was present in all our cadaveric dissections. The starting point of its pedicle ranged from 1.5 to 4.5 cm along the superficial circumflex iliac artery. The median diameter of the perforator and its concomitant vein was 1mm (range 0.8–2 mm). A cutaneous vein (1.3–2.3 mm) could be included in the flap if the concomitant vein was too small. Twenty consecutive patients had free SCIP flaps between 2002 and 2018. The indications were for finger defects (n = 8), thumb reconstruction (n = 1), lower limb compound fractures (n = 3), iatrogenic wounds (n = 2), upper limb large defects (n = 2), and scar contractures (n = 4). Flap dimensions ranged from 2 × 4 cm to 14 × 25cm, and the longest pedicle was 8cm. All flaps survived. The systematic literature review identified 34 previous reports using the SCIP flaps, most of these published by Asian units. Conclusion The SCIP flap is useful for reconstruction throughout the body due to its ease of dissection, thinness, adjustable pedicle length, and flap dimension ranging from tiny to large, as well as the feasibility of raising a compound flap incorporating an adipofascial or vascularized bone component if necessary.This is a level of evidence therapeutic IV study.

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Malanchin, D., R. Caruso, M. G. Nanni, L. Grassi, G. Piazza, E. Croce, M. Leoni, et al. "Preliminay study for the Italian validation of the screen for cognitive impairment in psychiatry (SCIP)." European Psychiatry 41, S1 (April 2017): S331—S332. http://dx.doi.org/10.1016/j.eurpsy.2017.02.274.

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IntroductionThe screen for cognitive impairment in psychiatry (SCIP) is a brief, accessible scale designed for detecting cognitive deficits in psychiatric disorders.ObjectivesThe objective of this study is to test the SCIP's validity as a cognitive test by comparison with standard neuropsychological scale using the Pearson's correlation.Aims Test the convergent and discriminant validity of the SCIP within the Italian SCIP validation project.MethodsPatients between 18 and 65 years who are in a stable phase of the disease, diagnosed with schizophrenia, schizoaffective disorder or bipolar I disorder were enrolled in this study, from the community mental health department of Ferrara.ResultsThe tests were administered to 110 patients (mean age: 45 ± 11,4) and to 86 controls (mean age: 35 ± 12,6) of both sex. SCIP presents high correlation with the R-BANS total score (P < 0.01) and the subscales (verbal learning test-immediate, working memory, verbal fluency test, verbal learning test-delayed, processing speed test, P < 0.01). There are significant differences (P < 0.01) in all SCIP dimensions between patient and control group (Table 1).ConclusionsOur analysis confirm the results of the English, French and Spanish version of the SCIP regarding convergent and discriminant validity. The SCIP represents a valid, simple and brief screening tool for the cognitive evaluation of patients with schizophrenia-spectrum disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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shirzad, galin, Juana Gomez Benito, Georgina Guilera, Emilio Rojo, and Oscar Pino. "M50. THE PERSIAN VERSION OF THE SCREEN FOR COGNITIVE IMPAIRMENT IN PSYCHIATRY (SCIP-P) AS A VALID SCREENING TOOL FOR COGNITIVE IMPAIRMENT IN SCHIZOPHRENIA." Schizophrenia Bulletin 46, Supplement_1 (April 2020): S153. http://dx.doi.org/10.1093/schbul/sbaa030.362.

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Abstract Background The Screen for Cognitive Impairment in Psychiatry (SCIP; Purdon, 2005) is a screening tool of cognitive impairment that includes measures of verbal learning (immediate and delayed), working memory, verbal fluency, and psychomotor speed. The test has three alternative forms that require less than 15 minutes to complete. The main objective of this preliminary study was to examine the Persian version of SCIP as a screening tool for cognitive dysfunction in schizophrenia. Methods Reliability and validity data were collected from a sample of 98 patients diagnosed with schizophrenia who completed three alternate forms of the Persian translations of the SCIP within a three-week period separated by a one-week delay. Results This study presents the first results of the Persian version of the SCIP in a sample of patients diagnosed with schizophrenia and compares the results with those derived from the English and Spanish versions. Discussion The SCIP-P scores were reliable and valid for the detection of cognitive impairment in schizophrenia. Analyses confirmed that the three forms of the SCIP-P are equivalent and may prove useful for the rapid screening during routine clinical evaluation of schizophrenia.

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Stoodley, Lynda, and Shu-Fen Wung. "Hyperglycemia After Cardiac Surgery." AACN Advanced Critical Care 25, no. 3 (July 1, 2014): 221–27. http://dx.doi.org/10.4037/nci.0000000000000028.

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Background The Surgical Care Improvement Project #4 (SCIP#4) performance measure is used to evaluate achievement of target blood glucose control after cardiac surgery. Objectives The purpose of this study was to identify patient characteristics and outcomes in patients undergoing cardiac surgery who met the SCIP#4 performance measure versus those who did not. Methods A retrospective case-control design was used. Results Preoperative hemoglobin A1C (HbA1C) level and history of diabetes were 2 major risk factors for failing to meet the SCIP#4 measure. A trend toward a longer length of stay was observed, mortality was 3 times more prevalent, and renal failure was 4 times more frequent in patients who did not meet the SCIP#4 quality measure. Conclusions Not meeting the SCIP#4 measure is associated with adverse outcomes. History of diabetes and preoperative HbAIC level should be considered when evaluating strategies for managing postsurgical hyperglycemia.

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Kuhn, R., E. S. Monuki, and G. Lemke. "The gene encoding the transcription factor SCIP has features of an expressed retroposon." Molecular and Cellular Biology 11, no. 9 (September 1991): 4642–50. http://dx.doi.org/10.1128/mcb.11.9.4642-4650.1991.

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SCIP is a POU domain transcription factor expressed by glial progenitor cells in the peripheral and central nervous systems (dividing Schwann cells and O-2A cells, respectively), where it appears to act as a repressor of myelin-specific genes. We have isolated genomic clones encoding the rat SCIP gene. Comparison of the structure of these clones with genomic Southern blots and SCIP cDNAs demonstrates that SCIP is encoded in a single-copy, intronless gene that has the general features of an expressed retroposon. This gene contributes to an extended CpG island. It is transcribed to produce a 3.1-kb mRNA that encodes a 451-amino-acid protein with a predicted molecular mass of 45 kDa. Immunopurified SCIP antibodies specifically recognize a nuclear protein of this size in cultured proliferating Schwann cells, and gel shift analyses demonstrate that this protein is the predominant octamer-binding protein in these cells.

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Kuhn, R., E. S. Monuki, and G. Lemke. "The gene encoding the transcription factor SCIP has features of an expressed retroposon." Molecular and Cellular Biology 11, no. 9 (September 1991): 4642–50. http://dx.doi.org/10.1128/mcb.11.9.4642.

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SCIP is a POU domain transcription factor expressed by glial progenitor cells in the peripheral and central nervous systems (dividing Schwann cells and O-2A cells, respectively), where it appears to act as a repressor of myelin-specific genes. We have isolated genomic clones encoding the rat SCIP gene. Comparison of the structure of these clones with genomic Southern blots and SCIP cDNAs demonstrates that SCIP is encoded in a single-copy, intronless gene that has the general features of an expressed retroposon. This gene contributes to an extended CpG island. It is transcribed to produce a 3.1-kb mRNA that encodes a 451-amino-acid protein with a predicted molecular mass of 45 kDa. Immunopurified SCIP antibodies specifically recognize a nuclear protein of this size in cultured proliferating Schwann cells, and gel shift analyses demonstrate that this protein is the predominant octamer-binding protein in these cells.

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Kummer, Beate, Henning Friege, Barbara Zeschmar-Lahl, and Jörg Wagner. "Nützen Scip-Daten der Abfallwirtschaft?" UmweltMagazin 51, no. 03-04 (2021): 30–32. http://dx.doi.org/10.37544/0173-363x-2021-03-04-30.

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Chemie spielt beim Recycling künftig eine größere Rolle. So soll „Scip“ – die neue Datenbank der EU – dafür sorgen, dass sehr gefährliche Schadstoffe nicht mit recycelt werden. Gute Idee! Doch drei Fallbeispiele zeigen, dass dies in der Praxis nicht einfach zu erreichen ist.

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Achterberg, Tobias. "SCIP: solving constraint integer programs." Mathematical Programming Computation 1, no. 1 (January 20, 2009): 1–41. http://dx.doi.org/10.1007/s12532-008-0001-1.

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Francis, Gregory. "Introduction to SCiP special issue." Behavior Research Methods 44, no. 3 (August 22, 2012): 607. http://dx.doi.org/10.3758/s13428-012-0251-8.

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Prescott, John. "A competitive assessment of SCIP." Competitive Intelligence Review 2, no. 1 (1991): 1–2. http://dx.doi.org/10.1002/cir.3880020102.

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Meurisse, Mike. "Scip Europe conference and AGM." Competitive Intelligence Review 4, no. 2-3 (1993): 67–68. http://dx.doi.org/10.1002/cir.3880040216.

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Kalb, Clifford C. "Beyond Competitive Intelligence: Repositioning SCIP." Competitive Intelligence Review 10, no. 4 (1999): 1–2. http://dx.doi.org/10.1002/(sici)1520-6386(199934)10:4<1::aid-cir1>3.0.co;2-j.

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Ashmead, Graham, Loyal Coshway, Heidi Rumancik, Rose Sevcik, Saeid Amini, and Melissa Herbst. "Smoking cessation in pregnancy (SCIP)." American Journal of Obstetrics and Gynecology 189, no. 6 (December 2003): S129. http://dx.doi.org/10.1016/j.ajog.2003.10.242.

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Altiparmak, Mehmet, Han Gyu Cha, Joon P. Hong, and Hyunsuk Peter Suh. "Superficial Circumflex Iliac Artery Perforator Flap as a Workhorse Flap: Systematic Review and Meta-analysis." Journal of Reconstructive Microsurgery 36, no. 08 (June 29, 2020): 600–605. http://dx.doi.org/10.1055/s-0040-1713666.

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Abstract Background There are various advantages and disadvantages attributed to superficial circumflex iliac artery perforator (SCIP) flap. The aim of this study is to evaluate the versatility and reliability of free SCIP flap by performing a systematic review and meta-analysis of the literature in terms of flap characteristics, pedicle types, and outcomes, including the different types of flap elevations. Methods PubMed, Embase OVID, and Cochrane CENTRAL were searched up to January 2019. All original articles and case reports published in English were included in the analysis. Anatomic descriptions, cadaveric studies, conference presentations, letter to the editors, local SCIP flaps, and review articles were excluded. Results A total of 36 articles including 907 SCIP flaps were available for the analysis. The most frequent causes of defects were tumors (38.2%) and lower extremities were the most common recipient areas (62.7%). The average flap dimension was 73.3 ± 23.0 cm2 with a pedicle length of 5.0 ± 0.6 cm. Vessel diameter average was 0.67 ± 0.12 mm. The average number of deep branch and superficial branch used per study was 14.4 ± 8.7 (18%) and 93.3 ± 75.0 (84%), respectively. Flap failure rate and complication rate were 2.7 and 4.2%, respectively. Conclusion SCIP flaps have been shown to be versatile in various aspects of reconstruction. The attributed disadvantages such as having short pedicle and small vessel diameter do not seem to limit the variable usage of this flap. Therefore, SCIP flap should be considered a workhorse flap.

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Qiu, Kai, Youbiao Ma, Uchechukwu Edna Obianwuna, Jing Wang, Haijun Zhang, Guanghai Qi, and Shugeng Wu. "Application of Selenium Conjugated to Animal Protein in Laying Hens’ Diet for the Production of Selenium-Enriched Eggs." Foods 10, no. 6 (May 28, 2021): 1224. http://dx.doi.org/10.3390/foods10061224.

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The current experiment was conducted to investigate the application effects of selenium conjugated to insect protein (SCIP) in the production of selenium-enriched eggs. A total of 450 laying hens were randomly assigned to five dietary groups, each group consisting of six replicates. Hens in the control group received a diet without selenium supplementation, whereas hens in the other four groups received diets supplemented with either 1, 2, 5, or 10 mg/kg of selenium from SCIP. The productive performance, egg quality, antioxidant and immune capacity, biochemical indices, intestinal morphology, and oviduct health of laying hens were evaluated. The results showed that the supplementation of organic selenium provided by SCIP in the diets of laying hens enhanced performance and egg quality without any toxicity effect, even at the 10 mg/kg inclusion level. A level of 2 mg/kg of selenium provided by SCIP in diets tentatively improved the serum antioxidant and immune capacity, intestinal development, and oviduct health of laying hens in a conspicuous manner. Hence, the biosafety and positive effects of SCIP as a feed additive supplement in laying hens’ diet have been demonstrated with the enhanced production of safe and selenium-enriched eggs.

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Calof, Jonathan. "Canadian competitive intelligence practices – a study of practicing strategic and competitive intelligence professionals Canadian members." foresight 19, no. 6 (November 13, 2017): 577–89. http://dx.doi.org/10.1108/fs-07-2017-0024.

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Purpose With intelligence (a field related to foresight) practice growing, the purpose of this study was to examine the practices of Canadian competitive intelligence (CI) practitioners. Design/methodology/approach Survey of Canadian CI practitioners who are SCIP members (Strategic and Competitive Intelligence Professional), using a revision to a previously used instrument designed to examine competitive intelligence practices. Findings Canadian SCIP member competitive intelligence practices seem to be more formalized than those found in the global SCIP study in 2006 with 84.8 per cent having a manager with CI responsibilities, 61 per cent with a formal centralized CI unit and only 9 per cent responding that CI was done informally. Intelligence units were generally smaller with 38 per cent having one full-time CI resource and 41 per cent having between 2 and 4 full-time resources. Additional findings on information sources used, analytical techniques used, evaluation methods and communication methods are reported. Research limitations/implications Despite getting responses from close to 50 per cent of SCIP members, the small sample size (79) makes it difficult to generalize the results beyond the Canadian SCIP environment and limits the testing that can be done. Originality/value The last study on Canadian competitive intelligence practices was in 2008, thus part of the originality of the study was getting more recent information on corporate intelligence practice. In addition, this is the first Canadian study to focus specifically on known intelligence practitioners (SCIP members). Past studies focused on companies in general regardless of whether respondents knew what competitive intelligence was or practiced CI.

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Abourokbah, Safinaz H., Reem M. Mashat, and Mohammad Asif Salam. "Role of Absorptive Capacity, Digital Capability, Agility, and Resilience in Supply Chain Innovation Performance." Sustainability 15, no. 4 (February 16, 2023): 3636. http://dx.doi.org/10.3390/su15043636.

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Digitalization is essential for supply chain (SC) systems to thrive in the extremely dynamic and competitive business environment of the present day. The purpose of this study is to examine the role and the importance of absorptive capacity (ACAP) on supply chain innovation performance (SCIP), mediated by digital capability (DCAP), supply chain resilience (SCR), supply chain agility (SCA), and digital innovation (DI). The study has been designed to empirically investigate the hypothesized relationships on a sample of 116 firms across industries in Saudi Arabia, using a partial least-squares-based structural equation model (PLS-SEM). Based on the findings, all the hypothesized paths are supported, justifying that ACAP positively and significantly impacts DCAP, SCA, and SCR. Moreover, SCA and SCR partially mediated the relationship between ACAP and SCIP. This study contributes to the resource-based view (RBV) and a dynamic capability (DC) theories by examining how the innovation of digital technologies affects SCIP, providing empirical support to the ACAP and SCIP interaction through numerous mediators to develop SCIP, from which also many practical implications emerged. For instance, especially in the wake of the COVID-19 pandemic, businesses must improve their SC performance by building and integrating their ACAP to make the most of their digital-platform-based dynamic capabilities.

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Norman, Kay. "A student coaching in practice (SCiP) approach: the impact on adult field pre-registration nursing students." British Journal of Nursing 31, no. 15 (August 11, 2022): 800–806. http://dx.doi.org/10.12968/bjon.2022.31.15.800.

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Background: A ‘student coaching in practice’ (SCiP) approach, based on the OSCAR and GROW model of coaching, was implemented across three UK NHS trusts in the West Midlands, involving seven placement areas that consisted of both acute and community hospital settings. Aim: To explore the impact of a SCiP approach on preparing students for their next stage of learning and perceived confidence. Method: Seventy nursing students across Years 1, 2 and 3 of their BSc (Hons) programme took part in the study through completing an evaluative survey consisting of both quantitative and qualitative responses. Ethical approval was obtained by the host university. Findings: Participants across each year group found SCiP beneficial in developing learning and skills in practice, helped them prepare for the next stage of learning or registration, and increased perceived confidence. Students in year 1 and year 3 of their nursing programme gave the most positive responses. Implementing SCiP resulted in the expansion of placement capacity.

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Iida, Takuya. "Superficial Circumflex Iliac Perforator (SCIP) Flap: Variations of the SCIP Flap and Their Clinical Applications." Journal of Reconstructive Microsurgery 30, no. 07 (April 2, 2014): 505–8. http://dx.doi.org/10.1055/s-0034-1370360.

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