To see the other types of publications on this topic, follow the link: Screening. Treatment.

Dissertations / Theses on the topic 'Screening. Treatment'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Screening. Treatment.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Kalina, Emily Jean. "Standardized Postpartum Depression Screening and Treatment." Diss., North Dakota State University, 2015. http://hdl.handle.net/10365/24837.

Full text
Abstract:
Postpartum depression affects 7 to 20% of women in the first year after giving birth. Unfortunately, over 50% of women experiencing postpartum depression go untreated due to lack of detection, placing the woman and child at risk for detrimental consequences. One of the most common barriers in detecting and treating postpartum depression is the low incidence of screening performed at primary care and obstetrical visits during the postpartum period. Efforts have focused on improving identification of postpartum depression through the use of a valid screening tool performed throughout the first y
APA, Harvard, Vancouver, ISO, and other styles
2

Silberholz, John. "Analytics for Improved Cancer Screening and Treatment." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/101290.

Full text
Abstract:
Thesis: Ph. D., Massachusetts Institute of Technology, Sloan School of Management, Operations Research Center, 2015.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 139-156).<br>Cancer is a leading cause of death both in the United States and worldwide. In this thesis we use machine learning and optimization to identify effective treatments for advanced cancers and to identify effective scr
APA, Harvard, Vancouver, ISO, and other styles
3

Pykare, Justin D. "Screening for Adverse Childhood Experiences in Medication-Assisted Treatment." Kent State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=kent1617798934883737.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Aubert-Jürgens, Ana. "STAT3 inhibitors for cancer treatment." [S.l.] : [s.n.], 2005. http://elib.tu-darmstadt.de/diss/000563.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Rajan, Suparna. "Screening for and treatment of cobalamin deficiency in older adults /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/6596.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Tatum, Natalie Joan. "Discovery by virtual screening of ethionamide boosters for tuberculosis treatment." Thesis, Durham University, 2015. http://etheses.dur.ac.uk/11315/.

Full text
Abstract:
Tuberculosis remains the world’s deadliest communicable bacterial disease with an unacceptably high death rate. In 2013 an estimated 1.5 million people died as a direct result of TB, and nine million new cases were reported. Multi-drug resistant (MDR) and extensively drug-resistant (XDR) tuberculosis cases are on the rise and without novel approaches to combat their spread, tuberculosis will continue to claim the lives of millions worldwide. One such novel approach is to rejuvenate the use of the second-line antibiotic ethionamide. Ethionamide is a structural analogue of the first-line pro-dru
APA, Harvard, Vancouver, ISO, and other styles
7

Jones, Simon Keith. "Mathematical modelling for early detection and treatment of cancer." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241869.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Bakker, Egbert. "Congenital hypothyroidism beyond neonatal T4 screening progress in diagnostics and treatment /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/81207.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Ellison, Tracy Louise. "The development of an improved screening and treatment strategy for diabetes." Thesis, Keele University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436189.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Watson, Gloria Marcia. "Women's Perspectives on Adequacy of Screening and Treatment for Postpartum Depression." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/1593.

Full text
Abstract:
Postpartum depression affects some 10% to 20% of mothers. Its impact on the health and well-being of mothers and their infants is well documented. If not identified and addressed early, it can result in emotional burden, costly hospitalization and treatment, and, at worst, suicide and or infanticide. Empowerment theory was the conceptual framework for this hermeneutic phenomenological study. The purpose was to understand the lived experiences of the screening and treatment processes of 10 women from New York City experiencing postpartum depression and their perceived adequacy of the treatment
APA, Harvard, Vancouver, ISO, and other styles
11

Frasier, Velma Asneth. "Increasing Depression Screening and Treatment for Adults Living with HIV/AIDs." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7540.

Full text
Abstract:
The lifetime prevalence of clinical depression in patients living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is approximately 22% compared to 3% to 10% in the primary care population. The nursing practice problem at the project site concerned nurses' lack of knowledge and understanding of procedures to help ensure that all patients living with HIV/AIDS were properly screened for depression and referred for further evaluation and treatment. The purpose of this project was to implement a staff education module to address the use of the PHQ-9 screening tool t
APA, Harvard, Vancouver, ISO, and other styles
12

Shi, Yuzhen. "Algae screening and acclimation for acetaldehyde removal and fermentation gas effluent treatment." Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/10514/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
13

Gminski, Elizabeth April. "Barriers to Screening, Diagnosis, and Treatment of Type 2 Diabetes in the Pediatric Population within a Military Treatment Facility." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/612834.

Full text
Abstract:
Type 2 Diabetes Mellitus (T2DM) was once a disease process found only in the adult population. However, incidence rates of T2DM in children and adolescents are increasing at alarming rates and becoming a grave public health concern. As many as 5,089 individuals under the age of 20 are newly diagnosed with T2DM each year. The military community is not immune to these national trends and T2DM among military dependents is growing at similar rates to that of the civilian population. The primary aim of this DNP project was to investigate if barriers exist with regard to pediatric military dependent
APA, Harvard, Vancouver, ISO, and other styles
14

Wei, Xin. "An Optimal Solution on Screening and Treatment of Chlamydia Trachomatis and Neisseria Gonorrhoeae." Digital Archive @ GSU, 2007. http://digitalarchive.gsu.edu/math_theses/35.

Full text
Abstract:
We propose a resource allocation model for the management of the fund for the screening and treatment of women infected by Chlamydia trachomatis and Neisseria gonorrhoeae. The goal is to maximize the number of infected women cured of Chlamydia trachomatis and Neisseria gonorrhoeae infections. The population going for screening is divided into groups by ages and races. The group number is dynamic. Dierent groups have dierent infection rates. There are four possible test assays and four possible treatments. We employed a two-phase algorithm to solve the problem. The first phase is small so an ex
APA, Harvard, Vancouver, ISO, and other styles
15

Nadjarian, Albert H. "An evaluation of screening, brief intervention, and referral to treatment in emergency departments." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12169.

Full text
Abstract:
Thesis (M.A.)--Boston University<br>Alcohol use disorders are major national public health problems that are responsible for impaired health. The emergence of SBIRT (Screening, Brief Intervention, and Referral to Treatment) has potentially revolutionized the strategies used to reach the at-risk population of drinkers, specifically within emergency departments (EDs). Several studies have confirmed the efficacy of SBIRT as a viable ED intervention method. Improved study measures have included keeping appointments for treatment, decreased average alcohol consumption and heavy episodic drinking, r
APA, Harvard, Vancouver, ISO, and other styles
16

Teale, Alison Mary Jennifer. "Breast cancer in the West Midlands : an evaluation of screening, treatment and survival." Thesis, University of Birmingham, 1997. http://etheses.bham.ac.uk//id/eprint/207/.

Full text
Abstract:
High quality population based data are essential to evaluate breast cancer. This study has improved data quality at the West Midlands Cancer Intelligence Unit through the development of a staging algorithm which significantly increased the proportion of cases with stage recorded. It has also demonstrated the benefits of combining cancer registry data with those from the NHS Breast Screening Programme (NHSBSP). This study identified stage as the most significant prognostic factor for breast cancer patients, and the favourable staging characteristics of screen detected cancers thus suggest that
APA, Harvard, Vancouver, ISO, and other styles
17

Rice, Ellen. "The impact of treatment and screening for diabetes complications on emergency department use." CONNECT TO ELECTRONIC THESIS, 2008. http://hdl.handle.net/1961/6863.

Full text
APA, Harvard, Vancouver, ISO, and other styles
18

Marerro, Magaly V. (Magaly Victoria). "Primary Care Screening for Psychological Factors." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc331793/.

Full text
Abstract:
The Behavioral Medicine Questionnare (BMQ) is a 44- item instrument administered via a computer CRT display or pencil and paper. The BMQ was designed to help primary care physicians treating spinal disorders to screen for emotional factors which warrant further psychological evaluation. The test is composed of three scales: Anxiety, Depression, and Somatization. Concurrent validity for each scale was determined through comparisons with subject (n = 133) scores on clinician judgement ratings, pain drawings, and the MMPI. The psychometric properties of the test were supported through statistical
APA, Harvard, Vancouver, ISO, and other styles
19

Wilson, Gayle Pamela. "Optimisation of an in vitro model for anti-diabetic screening." Thesis, Nelson Mandela Metropolitan University, 2006. http://hdl.handle.net/10948/428.

Full text
Abstract:
The need for alternative strategies for the prevention and treatment of diabetes is growing rapidly as type II diabetes is reaching epidemic status in our society. This need was the basis for the creation of this study, as it was necessary to start looking towards medicinal plants as potential antidiabetic treatment and no comprehensive in vitro model existed. In creating a model for determining the effects of alternative traditional medicines as antidiabetic potentiates, it was necessary that two metabolic pathways, namely glucose uptake and insulin secretion, which play a significant role in
APA, Harvard, Vancouver, ISO, and other styles
20

Winters, Brittany N. "The psychometric utility of the Drug Abuse Screening Test among treatment-seeking, homeless men." Thesis, Pepperdine University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3622742.

Full text
Abstract:
<p> Homelessness in the United States is recognized as a grave societal problem with longstanding and pervasive implications. A substantial body of research has shown that substance use disorders occur at higher rates among homeless adults than among housed persons. Mental disorders, particularly depressive disorders, are also known to occur at substantially higher rates among the homeless. Given the prevalence of these conditions, it is important that clinicians working with homeless adults have access to reliable and valid assessment tools. The purpose of this study was to examine the useful
APA, Harvard, Vancouver, ISO, and other styles
21

Hujoel, Margaux L. "Assessment of Treatment and Screening Procedures for Chlamydia trachomatis Infections in a College Setting." Scholarship @ Claremont, 2016. http://scholarship.claremont.edu/hmc_theses/86.

Full text
Abstract:
Chlamydia trachomatis infections are a common sexually transmitted infection in the United States in which the majority of cases are asymptomatic. Due to this asymptomatic nature, as well as the serious health issues that arise from untreated infections in women, the Centers for Disease Control and Prevention (CDC) recommends a screening policy that annually targets women between the ages of 15 and 25 or older women with risk factors. There is little evidence supporting the efficacy of only screening women and doing so once per year. Through a stochastic epidemiological model, we investigate a
APA, Harvard, Vancouver, ISO, and other styles
22

Dzidowska, Monika. "A Cluster Randomised Trial to Support Screening and Treatment for Unhealthy Alcohol Use in Aboriginal Community Controlled Health Services." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29409.

Full text
Abstract:
Background: Evidence-based management of unhealthy alcohol use in primary care has been advocated since 1979. Few studies focus on improving implementation of alcohol screening and treatment in Indigenous primary care, despite greater harms from alcohol in that population group. Aims: To examine: (i) approaches used to improve screening and treatment for unhealthy alcohol use in primary care internationally; (ii) the effects of the 24-months’ support offered to 22 Aboriginal Community Controlled Health Services on screening and treatment for unhealthy alcohol use. Methods: Study 1 (syste
APA, Harvard, Vancouver, ISO, and other styles
23

Wang, An Qi. "Screening of hepatoprotective constituents from herbal medicines and investigation on the underlying mechanisms." Thesis, University of Macau, 2017. http://umaclib3.umac.mo/record=b3690819.

Full text
APA, Harvard, Vancouver, ISO, and other styles
24

Chan, Ka-wai Christina, and 陳嘉慧. "The cost-effectiveness of early screening and treatment for intermediate age-related macular degeneration (AMD)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48422460.

Full text
Abstract:
OBJECTIVE To determine whether grading for AMD during a diabetic retinopathy (DR) screening program would be cost-effective in Hong Kong. METHODS A cost-effectiveness analysis based on a Markov model with six mutually exclusive health states was undertaken. It included grading for AMD and treatment with vitamin therapy for those with intermediate AMD. The outcome of the model was cost per quality-adjusted life year (QALY) gained. A public provider perspective was used. The measures of effectiveness were mostly taken from a local DR screening project except the transition probabilities
APA, Harvard, Vancouver, ISO, and other styles
25

Wentzel, Annalie. "Determinants of compliance behaviour among patients living with diabetes referred for diabetic retinopathy treatment in a government health care facility in Cape Town, South Africa." University of the Western Cape, 2020. http://hdl.handle.net/11394/8025.

Full text
Abstract:
Magister Public Health - MPH<br>Untreated and unmonitored diabetic retinopathy (DR) can lead to vision loss. This may have many negative implications on society. Currently, there is a dearth of evidence regarding the factors that influence compliance behaviour to treatment among patients diagnosed with DR in South Africa’s public healthcare system. The current study sought to fill this research gap and explore patient-, institution-, treatment-, and COVID-19- related factors associated with compliance behaviour among patients living with diabetes that have been referred for suspected vision-th
APA, Harvard, Vancouver, ISO, and other styles
26

Češkovičová, Petra. "Analýza nákladů terapie karcinomu prsu." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-135929.

Full text
Abstract:
The subject of this thesis is to identify and quantificate costs of Breast Cancer Therapy. The goal is the quantification of costs for specific therapeutic modalities, which are used by the therapy. Obtained values are used for presentation of the cheapest and the most expensive mode of treatment.
APA, Harvard, Vancouver, ISO, and other styles
27

Jeffries, Suzanna L. "An Evidence-Based Protocol for Optimal Screening and Treatment of Antenatal Depression: A Best Practice Approach." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/595043.

Full text
Abstract:
The purpose of this thesis was to develop a best practice protocol for the nursing care of pregnant women with antenatal depression. Approximately 11% of obstetrical clients experience antenatal depression at some point during their pregnancy (Banti et al., 2011). The periods associated with the highest incidence of depressive symptoms are the first and third trimesters (Bowen, Bowen, Butt, Rahman, & Muhajarine, 2012). In spite of the high occurrence of antenatal depression, many women go undiagnosed (Banti et al., 2011). Many of the pregnant women confirmed to be depressed do not receive trea
APA, Harvard, Vancouver, ISO, and other styles
28

Suh, Caitlin D. "The Use of High-Throughput Virtual Screening Software in the Proposal of A Novel Treatment for Congenital Heart Defects." Scholarship @ Claremont, 2019. https://scholarship.claremont.edu/cmc_theses/2260.

Full text
Abstract:
Conventional screening of potential drug candidates through wet lab affinity experiments using libraries of thousands of modified molecules is time and resource consuming, along with the fact that it contributes to the widening time gap between the discovery of disease-causing mutations and the implementation of resulting novel treatments. It is necessary to explore whether the preliminary use of high-throughput virtual screening (HTVS) software such as PyRx will curb both the time and money spent in discovering novel treatments for diseases such as congenital heart defects (CHDs). For example
APA, Harvard, Vancouver, ISO, and other styles
29

Musarapasi, Normusa. "Review of outcomes for isoniazid preventive therapy among HIV infected clients at a clinic in Swaziland." University of the Western Cape, 2019. http://hdl.handle.net/11394/6887.

Full text
Abstract:
Magister Public Health - MPH<br>Background: TB is one of the most common opportunistic infections in the HIV infected population. In 2014, of the 9.6 million people estimated to have TB globally, 1.2 million were also infected with HIV. In the same year WHO reported 400 000 TB deaths in HIV infected people worldwide. TB Prevention strategies include ensuring HIV infected people take ART, TB infection control, treatment of TB cases and pharmacological prevention of primary TB infection or progression of latent TB into active TB. Isoniazid preventive therapy for a minimum of six months has been
APA, Harvard, Vancouver, ISO, and other styles
30

Jowett, Susan Marie. "Using decision analytical modelling techniques in health economics : application to screening for and treatment of atrial fibrillation." Thesis, University of Birmingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.440931.

Full text
APA, Harvard, Vancouver, ISO, and other styles
31

Häberlein, Felix [Verfasser]. "A humanized zebrafish screening platform to identify GPR17 inhibitors for the treatment of multiple sclerosis / Felix Häberlein." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1228978972/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
32

Carney, Tara. "Evidence-based screening, brief intervention and referral to treatment for substance-using adolescents with delinquent-type behaviours." Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/13182.

Full text
Abstract:
Includes bibliographical references.<br>Background: Both substance use and delinquent-type behaviours are prevalent among adolescents in Cape Town, South Africa. However, early interventions in developed countries for adolescents with similar problems are not available in many low and middle income countries, including South Africa. This is a concern as providing evidence-based interventions that address these dual behavioural problems may prevent their progression. There is thus a need for identifying and understanding the kinds of interventions that would be able to address both of these pro
APA, Harvard, Vancouver, ISO, and other styles
33

Flores, Johnny Martin. "The Substance Abuse Subtle Screening Inventory: a Predictive Validity Study with Criminal Offenders Mandated to Rehabilitative Treatment." Thesis, University of North Texas, 1996. https://digital.library.unt.edu/ark:/67531/metadc279233/.

Full text
Abstract:
The Substance Abuse Subtle Screening Inventory was constructed to screen for substance abuse patterns despite non-admittance of respondents. Predictive validity studies of the SASSI are limited, and are not available for probationers. Participants were 147 male and 54 female probationers mandated to treatment. Overall differences among SASSI scales were significant for treatment compliance and outcome. Higher SASSI scales were found among those probationers who were compliant/successful. Individual scales were not significantly different, however, a trend was revealed; those respondents who sc
APA, Harvard, Vancouver, ISO, and other styles
34

DeBoard, Ruth Ann. "Breast Abnormalities: Identification of Indicators that Facilitate Use of Health Services for Diagnosis and Treatment of Breast Cancer." Diss., The University of Arizona, 2010. http://hdl.handle.net/10150/195625.

Full text
Abstract:
Problem: There is a lack of knowledge about women who are screened for breast cancer, have an abnormal finding on mammogram, and then do not return in a timely manner for diagnostics and treatment. Lack of follow- up likely constitutes delayed treatment and poorer outcomes. Delays may result in later entry into the health system with advanced disease, more extensive and expensive care, burdening resources. Late stage breast cancer likely results in poorer health outcomes or early death.Purpose and Aims: The purpose of this research is to describe contextual characteristics at the health delive
APA, Harvard, Vancouver, ISO, and other styles
35

Henriksson, Martin. "Cost-effectiveness and Value of Further Research of Treatment Strategies for Cardiovascular Disease." Doctoral thesis, Linköping : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-9788.

Full text
APA, Harvard, Vancouver, ISO, and other styles
36

Martin, Michael. "Detection and Treatment of Mental Illness Among Prison Inmates: A Validation of Mental Health Screening at Intake to Correctional Service of Canada." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36479.

Full text
Abstract:
Mental health screening is frequently recommended to facilitate earlier detection of mental illness in prisons. For this goal to be achieved: (1) the screening process must be accurate; (2) appropriate follow-up treatment must be provided; (3) the treatment must lead to improved outcomes. The current thesis aimed to evaluate mental health screening in relation to these three criteria by studying 13, 281 prisoners admitted to Correctional Service of Canada. Screening achieved comparable accuracy to tools that have been studied internationally and many inmates received at least some treatment. H
APA, Harvard, Vancouver, ISO, and other styles
37

Elfgren, Kristina. "Longitudinal studies of human papillomavirus infection : with special reference to screening for cervical cancer and treatment of CIN /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-673-1/.

Full text
APA, Harvard, Vancouver, ISO, and other styles
38

Jaén, Gil Adrián. "Removal of pharmaceuticals in wastewater combining different treatment technologies: suspect screening identification and risk assessment of transformation products." Doctoral thesis, Universitat de Girona, 2021. http://hdl.handle.net/10803/673419.

Full text
Abstract:
The low efficiency of wastewater treatment plants to achieve the complete removal of micropollutants, including pharmaceuticals, has motivated the development of alternative water technologies to improve their efficiency, sustainability, and operational costs. However, even when the complete elimination of these contaminants is attained, they can be transformed into new and unknown intermediates which might be even more persistent and toxic than their parent compounds. In this doctoral thesis, the development of advanced suspect screening methodologies has been applied for the identification o
APA, Harvard, Vancouver, ISO, and other styles
39

Kerrins, Ryan, and Jean Hemphill. "Screening, Brief Intervention and Referral to Treatment (SBIRT): Process Improvement in a Nurse-Managed Clinic Serving the Homeless." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/12.

Full text
Abstract:
Purpose The Johnson City Downtown Day Center (JCDDC) provides integrated inter-professional primary care, mental health, and social work case management services to homeless and under-served persons who have difficulty accessing traditional systems. Because of the exponential rise in substance abuse in the Appalachian region, the JCDDC providers and staff initiated SBIRT as recommended standard of care, as endorsed by SAMHSA, United States Public Health Services Task Force, and the National Institute on Alcohol Abuse and Alcoholism. The JCDDC has two mechanisms by which patients can choose to
APA, Harvard, Vancouver, ISO, and other styles
40

Kerrins, Ryan B., and Jean Croce Hemphill. "Screening, Brief Intervention, and Referral to Treatment (SBIRT) Process Improvement in a Nurse-Managed Clinic Serving the Homeless." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/etsu-works/7558.

Full text
Abstract:
A nurse-managed clinic in Northeast Tennessee that mainly serves unstably housed patients launched a process improvement project to evaluate Screening, Brief Intervention, and Referral to Treatment (SBIRT) implementation and use. These findings could guide future SBIRT efforts among vulnerable groups.
APA, Harvard, Vancouver, ISO, and other styles
41

Kerrins, R., and Jean Croce Hemphill. "Screening, Brief Intervention, and Referral to Treatment (SBIRT): Process Improvement in a Nurse-Managed Clinic Serving the Homeless." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7577.

Full text
APA, Harvard, Vancouver, ISO, and other styles
42

Theodorou, Andria Soteri. "Screening and delineation of molecular mechanisms of action of HbF inducing agents for the treatment of β-thalassaemia". Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/screening-and-delineation-of-molecular-mechanisms-of-action-of-hbf-inducing-agents-for-the-treatment-of-thalassaemia(fbad43de-f2b2-49a1-980b-b6dfcc1a25c5).html.

Full text
Abstract:
Current agents used for pharmacological reactivation of foetal haemoglobin (HbF) have limited application due to moderate therapeutic properties, variable patient response and potential cytotoxic effects. Therefore, identification of novel HbF inducing agents is still a major research goal to this day. Identification of new potential HbF inducers has been mainly based on screening of drug libraries. However, this approach has not been very successful in generating new promising agents. In the current project, I employed two approaches for identifying potential HbF inducers: 1) screening of age
APA, Harvard, Vancouver, ISO, and other styles
43

Golovko, Olga. "The screening for novel proteasome inhibitors as a treatment of cancer using IncuCyte FLR and fluorometric microculture cytotoxicity assay." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160700.

Full text
Abstract:
The problem of finding targeted medicine is a central problem in chemotherapy. From this point of view the ubiquitin-proteasome system is a highly promising object in the pharmaceutical approach. Proteasome plays a critical role in cellular protein degradation, cell cycle and apoptosis regulation. Proteasome inhibitors are substances blocking the actions of proteasome. Cancer cells are more sensitive to inhibition of the ubiquitin-proteasome system than normal cells. Therefore proteasome inhibitors have the potential to be successfully used in the cancer treatment. The study aimed to test vari
APA, Harvard, Vancouver, ISO, and other styles
44

Nicholas, Rudi Berto. "In silico and in vitro screening of marrubiin and marrubiin derivatives for antidiabetic activity on PTP1ß, C2C12 myocytes, chang liver hepatocytes and 3T3-L1 adipocytes." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1020638.

Full text
Abstract:
Diabetes mellitus (DM) is a life changing disease which affects a large portion of the population and the economy through high medical costs and loss of productivity. Marrubiin (MAR), a diterpenoid isolated from Leonotis leonurus, a plant indigenous to Southern Africa, is used by traditional healers to alleviate DM symptoms. This study aims to screen the inhibitory potential of MAR and MAR derivatives on PTP1β and glucose uptake properties of Chang liver, C2C12 and 3T3-L1 cells. Marrubiin and 19 of its derivatives were tested to determine the inhibition constants for PTP1β. A Ki of 21 μM and 0
APA, Harvard, Vancouver, ISO, and other styles
45

Pabrai, Natasha Uday. "The Use of Anti-CD3 Treatment and Genetic Screening to Delay Further Beta Cell Destruction in Type 1 Diabetes." Scholarship @ Claremont, 2013. http://scholarship.claremont.edu/scripps_theses/284.

Full text
Abstract:
Individuals under 20 years old have the highest risk of developing type 1 diabetes because their beta cells are destroyed at a faster rate than any other age group. Previous studies have looked at delaying and slowing down the rate of beta cell destruction through the use of anti-CD3 antibody treatments. Specifically, Teplizumab and Otelixizumab drug therapies have been used to treat individuals within 12 weeks of diagnosis. Previous studies done with Teplizumab and Otelixizumab have focused on individuals between 12 and 40 years old; however, there is little research done the effects of these
APA, Harvard, Vancouver, ISO, and other styles
46

Kämppi, A. (Antti). "Identifying dental restorative treatment need in healthy young adults at individual and population level." Doctoral thesis, Oulun yliopisto, 2015. http://urn.fi/urn:isbn:9789526209128.

Full text
Abstract:
Abstract Dental caries is one of the most widespread diseases in the world. In the industrialized world the situation improved until the 1990s, after which the good development is claimed to have almost stagnated. One of the aims of this cross-sectional study was to investigate caries prevalence in a young male population. Another aim was to investigate ways to find individuals needing restorative treatment. The hypothesis in this study was that caries prevalence among Finnish young males born in the 1990s was similar or even poorer compared to those born in earlier decades. Polarization of de
APA, Harvard, Vancouver, ISO, and other styles
47

Olofsson, Ulrika. "Removal processes in sewage treatment plants : Sludge quality and treatment efficiency of structurally diverse organic compounds." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-51315.

Full text
Abstract:
Large and ever-increasing numbers of chemicals, including large quantities of a broad spectrum of organic compounds are used in modern society. More than 30 000 of the more than 100 000 chemical substances registered in the EU are estimated to be daily used, of which many will be discharged into the waste-streams handled by municipal sewage treatment plants (STPs). The main objective of the work underlying this thesis was to improve understanding of the relationships between the characteristics of sewage contaminants and their sewage treatment efficiency. Further objectives were to examine the
APA, Harvard, Vancouver, ISO, and other styles
48

Jansson, Stefan P. O. "A Longitudinal Study of Diabetes Mellitus : With Special Reference to Incidence and Prevalence, and to Determinants of Macrovascular Complications and Mortality." Doctoral thesis, Uppsala universitet, Allmänmedicin och preventivmedicin, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-210916.

Full text
Abstract:
Objectives. To investigate diabetes prevalence, incidence, mortality trends, the effects of hyperglycaemia and blood pressure, diabetes and hypertension treatment, and the effect of screening detection on total and cardiovascular disease (CVD), myocardial infarction (MI) and stroke incidence. Study population and methods. Between 1972 and 2001 all patients with diabetes, some detected clinically and some by case-finding procedures (screening), were entered in a diabetes register at Laxå Primary Health Care Center in Sweden. The register included information on medical treatment and laboratory
APA, Harvard, Vancouver, ISO, and other styles
49

Thorman, Alexander W. "Rational Design of Novel BCL2A1 Inhibitors for Treatment of Autoimmune Diseases: An Integration of Virtual Screening, Transcriptomics and Protein Biophysics." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543580409766192.

Full text
APA, Harvard, Vancouver, ISO, and other styles
50

Alexander, Henry George. "Factors associated with diabetic retinopathy requiring treatment on fundal photography in participants of the Cape Town diabetic retinopathy screening programme." University of the Western Cape, 2016. http://hdl.handle.net/11394/5498.

Full text
Abstract:
Magister Public Health - MPH<br>BACKGROUND AND RATIONALE: The Cape Town Metro District Health Service (MDHS) has introduced a Diabetic RetinopathyScreening (DRS) programme incorporating retinal fundal photography in diabetic services at primary health care (PHC) facilities. Hitherto, coverage of the DRS programme has been less than optimal in part due to volumes of diabetic patients attending PHC facilities. The aim of this study was to identify possible sub-groups of patients, attending the Cape Town DRS Programme, who are at most risk of diabetic retinopathy and might be prioritised for earl
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!