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Journal articles on the topic 'Sdom pa'

Author: Grafiati

Published: 4 June 2025

Last updated: 15 July 2025

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1

Mirzaeva, Saglara V. "To the Problem of Tibetan Texts from Tuvan Archives Related to Zaya pandita. Part 1." Бюллетень Калмыцкого научного центра Российской академии наук, no. 4 (December 8, 2024): 24–48. https://doi.org/10.22162/2587-6503-2024-4-32-24-48.

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This study has two parts, the first being presented in the paper. Here we consider five Tibetan-language manuscripts from the collections of the Tuvan Institute of Humanities and Applied Socio-Economic Research under the Government of the Republic of Tuva, in which colophons the name of Zaya-Pandita is mentioned. The first in this succession of reincarnations, including eight embodiments, was the renowned Buddhist scholar and translator Zaya pandita Namkha Jamtso (1599–1662), also known as creator of the Oirat todo bichig script. Research materials discussing Zaya pandita as a historical figur

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Safa, Farhana, Natalia McClellan, Sarah Bonato, Sergio Rueda, and Kelly K. O’Brien. "The Role of the Social Determinants of Health on Engagement in Physical Activity or Exercise among Adults Living with HIV: A Scoping Review." International Journal of Environmental Research and Public Health 19, no. 20 (2022): 13528. http://dx.doi.org/10.3390/ijerph192013528.

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Physical activity (PA) and exercise are an effective rehabilitation strategy to improve health outcomes among people living with HIV (PLWH). However, engagement in exercise among PLWH can vary. Our aim was to characterize the literature on the role of social determinants of health (SDOH) on engagement in PA or exercise among adults living with HIV. We conducted a scoping review using the Arksey and O’Malley Framework. We searched databases between 1996 and 2021. We included articles that examined PA or exercise among adults with HIV and addressed at least one SDOH from the Public Health Agency

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Swamy, Padma, Ana C. Monterrey, Margaret S. Wood, Catherine L. Troisi, and Christopher S. Greeley. "Caregiver and Pediatric Health Care Provider Views on Social Needs Identification." Journal of Primary Care & Community Health 11 (January 2020): 215013272092308. http://dx.doi.org/10.1177/2150132720923085.

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Background: The American Academy of Pediatrics recommends that pediatricians address the social determinants of health (SDOH) through research, community partnership, and policy development. Objective: This study aimed to identify the unmet SDOH of the patients served by the Pasadena-Pediatric and Adolescent Health Center (PA-PAHC) and to understand provider perspectives on screening for SDOH. Methods: The PA-PAHC is a low-income pediatric clinic in southeast Houston. A cross-sectional survey eliciting potential SDOH concerns was administered to caregivers of children presenting for their well

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Shah, Yash B., Zachary N. Goldberg, Erika D. Harness, and David B. Nash. "Charting a Path to the Quintuple Aim: Harnessing AI to Address Social Determinants of Health." International Journal of Environmental Research and Public Health 21, no. 6 (2024): 718. http://dx.doi.org/10.3390/ijerph21060718.

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The Quintuple Aim seeks to improve healthcare by addressing social determinants of health (SDOHs), which are responsible for 70–80% of medical outcomes. SDOH-related concerns have traditionally been addressed through referrals to social workers and community-based organizations (CBOs), but these pathways have had limited success in connecting patients with resources. Given that health inequity is expected to cost the United States nearly USD 300 billion by 2050, new artificial intelligence (AI) technology may aid providers in addressing SDOH. In this commentary, we present our experience with

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Pad+ma, rig 'dzin (Wanmarenzeng). "An A mdo Smyung gnas: Yo lag Tibetan Community, Thun rin (Reb gong, Tongren) City, Mtsho sngon (Qinghai) Province, PR China." ASIAN HIGHLANDS PERSPECTIVES 60 (August 19, 2021): 47–73. https://doi.org/10.5281/zenodo.5482239.

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Personal experiences, observations, preparations, daily activities, including recreational events, and interviews with locals, inform this study of a community A mdo Tibetan Smyung gnas held on the fourteenth to sixteenth days of the fourth (Chinese lunisolar calendar) in Yo lag (Zhiyue) Village, Mdo ba (Duowa) Town, Thun rin (Reb gong, Tongren) City, Mtsho sngon (Qinghai) Province, PR China during the mid-twentieth to the early twenty-first centuries. Cultural preservation is served by this study, which is also a model of how local rituals might be presented at a time of rapid cultural transf

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Angove, Rebekah SM, and Kathleen D. Gallagher. "Social determinants of health—to screen or not to screen? How, when, and what to do next are really the questions." Journal of Clinical Oncology 40, no. 28_suppl (2022): 169. http://dx.doi.org/10.1200/jco.2022.40.28_suppl.169.

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169 Background: Social determinants of health (SDOH) have a considerable impact on the health outcomes of chronically ill patients. Although the implementation of social needs screening in clinical settings has been studied, patient perspectives of discussing SDOH with health care providers has not been thoroughly investigated. This study sought to explore the experience and perspectives of limited-resource patients with cancer regarding SDOH discussions. Methods: This cross-sectional analysis used data from a nationwide survey distributed in May 2022 by Patient Advocate Foundation (PAF). The

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Tingley, Hilary, Madeline McIntosh, McKenzie Klee, Margaret Gladman, Alison Coogan, and Andrea Madrigrano. "Abstract PO3-09-08: Using Social Determinants of Health to Improve Surgical Delays for Breast Cancer Patients at Rush University Cancer Center." Cancer Research 84, no. 9_Supplement (2024): PO3–09–08—PO3–09–08. http://dx.doi.org/10.1158/1538-7445.sabcs23-po3-09-08.

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Abstract Introduction Delays to surgery in the treatment of breast cancer can lead to worse disease specific mortality and overall survival. Previous work has shown a woman’s time to surgical treatment is influenced by income, which may be secondary to social determinants of health (SDOH) including health literacy, safety, stress, access to health care and transportation, housing, and ability to pay utilities. This study sought to evaluate a screening process for SDOH to assess and address barriers to care for women newly diagnosed with breast cancer. Methods A SDOH screening tool consisting o

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Zasloff, Rebecca A., Alexandra Hunter, Ayush Khanna, Huda Haque, Elizabeth R. Blackwood, and Nosayaba Osazuwa-Peters. "Abstract 4892: Tools for screening for social determinants of health in head and neck cancer: a scoping review." Cancer Research 85, no. 8_Supplement_1 (2025): 4892. https://doi.org/10.1158/1538-7445.am2025-4892.

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Abstract Methods: We conducted a systematic literature search of Medline, Embase, and Web of Science databases on July 24, 2024. The included studies were US-based, written in English, and examined a validated tool to assess SDoH among HNC patients. Tools were categorized by the five primary SDoH domains as defined by the Healthy People 2030 Initiative: Economic Stability, Education Access and Quality, Social and Community Context, Health Care Access and Quality, and Neighborhood and Built Environment. Subdomains within each primary domain were used to further categorize the included tools. Re

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Ogunrinde, Joyce. "EXPLORING CULTURALLY RESPONSIVE PHYSICAL ACTIVITY AS A RECRUITMENT AND RETENTION TOOL FOR AFRICAN AMERICAN WOMEN." Innovation in Aging 6, Supplement_1 (2022): 553–54. http://dx.doi.org/10.1093/geroni/igac059.2095.

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Abstract Physical activity (PA) is associated with lower cognitive decline and incident dementia for older adults. Yet, PA data (interventions) on older African American (AA) women, a population disproportionately affected by premature aging, are lacking. This limitation reduces the efficacy of PA to reduce cognitive decline, particularly for people of color and more so women of color whose race and gender create unique spaces for PA engagement. Although AA women desire to engage in PA, they face social, structural, and behavioral barriers to PA, challenges that parallel those faced in prevent

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Nagase, T., M. Lei, F. M. Robatto, D. H. Eidelman, and M. S. Ludwig. "Tissue viscance during induced constriction in rabbit lungs: morphological-physiological correlations." Journal of Applied Physiology 73, no. 5 (1992): 1900–1907. http://dx.doi.org/10.1152/jappl.1992.73.5.1900.

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Tissue viscance (Vti), the pressure drop across the lung tissues in phase with flow, increases after induced constriction. To gain information about the possible site of response, we induced increases in Vti with methacholine (MCh) and attempted to correlate these changes with alterations in lung morphology. We measured tracheal (Ptr) and alveolar pressure (PA) in open-chest rabbits during mechanical ventilation [frequency = 1 Hz, tidal volume = 5 ml/kg, positive end-expiratory pressure (PEEP) = 5 cmH2O] under control conditions and after administration of saline or MCh (32 or 128 mg/ml) aeros

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McCormack, Kara. "Abstract C005: Social determinants and environmental exposures and their localized contribution to risk of cancer mortality." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): C005. http://dx.doi.org/10.1158/1538-7755.disp22-c005.

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Abstract When considering environmental exposures and/or social determinants of health (SDOH), data are typically available by counties, zip codes or census tracts. We consider two quantitative challenges in this setting when modeling cancer outcomes. The first is that multiple, potentially highly correlated exposures may contribute to risk. The second is that the spatial correlation of such features may not follow the original models designed for disease risk mapping. While several conditional autoregressive (CAR) models are typically utilized (Besag et al. (1991), Leroux et al. (1999), Stern

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Alghamdi, Ahmad, and Farid Fadhillah. "Thin film composite polyelectrolyte multilayer nanofiltration membrane fabricated using spin assisted layer by layer assembly: Application of solution diffusion film model." Communications in Science and Technology 5, no. 1 (2020): 10–15. http://dx.doi.org/10.21924/cst.5.1.2020.177.

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Thin Film Composite (TFC) Polyelectrolyte Multilayer (PEM) Nanofiltration (NF) membrane consisting of multilayer of Poly(diallyl dimethyl ammonium chloride) (PDAC) and Poly(sodium 4-styrenesulfonate) (PSS) deposited on polyethersulfone (PES) support was prepared using spin-assisted layer by layer assembly (SA-LbL). This work is an effort to discover new material having better characteristics and performance than commercial polyamide (PA) NF membrane. Two main operating conditions namely temperature and salt concentration were investigated and the effect of both on membrane performance was stud

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Ramsey-Goldman, Rosalind, Justin Arnold, Dominique Kinnett-Hopkins, et al. "IS PHYSICAL ACTIVITY (PA) BEHAVIOR ANOTHER CASUALTY OF DEPRIVED NEIGHBORHOODS IN PERSONS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)?" Journal of Rheumatology 52, Suppl 1 (2025): 122.3–123. https://doi.org/10.3899/jrheum.2025-0390.pv076.

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PV076 / #248Poster Topic:AS10 - Environment and SLEBackground/PurposeSLE, a chronic inflammatory, autoimmune disease with pervasive self-reported fatigue, negatively impacts most individuals with SLE. Because of its recognized benefits in improving oxygen capacity and endurance, physical activity (PA) is one modifiable lifestyle behavior to help reduce fatigue in patients with SLE who are typically not physically active and afraid to exercise. Recent research suggests a role for Social Determinants of Health (SDOH) in identifying environmental impact on medical care and conditions. The Area De

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Venna, Alyssia, Yves d’Udekem, and Sabrina Figueiredo. "328 Identifying barriers and facilitators influencing physical activity levels in children and adolescents with congenital heart disease (CHD): A rapid review." Journal of Clinical and Translational Science 9, s1 (2025): 101. https://doi.org/10.1017/cts.2024.959.

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Objectives/Goals: Physical activity (PA) is critical to improving the health and well-being of patients with congenital heart disease (CHD); however, rates of PA, specifically in children and adolescents with CHD, remain significantly lower than the general population. Our goal was to understand what factors influence rates of PA in children and adolescents with CHD. Methods/Study Population: A rapid review was performed in February 2024 across 5 databases: PubMed, Scopus, CINAHL, PsycINFO, and PEDRO (PROSPERO 2024 CRD42024516250). A search strategy combined all possible terms and MESH terms r

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Aroh, Adaeze, and Ifeanyi N. Madujibeya. "Abstract A089: Examining the role of Social Determinants of Health (SDoH) on adherence to cancer prevention recommendations: Evidence from a national representative sample." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): A089. http://dx.doi.org/10.1158/1538-7755.disp23-a089.

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Abstract The role of Social Determinants of Health (SDoH) on adherence to cancer prevention recommendations has not been systematically examined among adults in the United States adults despite the influential role of SDoH in shaping individuals' health behaviors and outcomes. Our purpose was to explore the effects of SDoH on adherence to cancer prevention recommendations among adults in the United States Methods: We used data from the Health Information National Trends Survey (HINTS), 6 cycle (2022). Adults aged 18 years and above were included. Adherence to cancer prevention recommendations

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Giap, Fantine, Young-Rock Hong, Julie Ann Bradley, and Oluwadamilola Temilade Oladeru. "Social determinants of health factors and palliative care services use among patients with metastatic breast cancer in Florida." Journal of Clinical Oncology 41, no. 16_suppl (2023): 1102. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.1102.

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1102 Background: ASCO recommends palliative care (PC) as an adjunct to the oncologic standard of care for patients with metastatic cancer. However, current evidence on PC utilization in patients with breast cancer and its relationship with area-level social determinants of health (SDoH) factors is limited. Therefore, we examined the associations between county-level factors and PC utilization among patients with metastatic breast cancer (mBC) in Florida. Methods: We extracted patient-level data (n = 23,539 patients diagnosed with mBC between 2012 and 2021) from the OneFlorida+ Data Trust and l

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Ramirez, Amelie G., Derek Rodriguez, Cliff Despres, et al. "Abstract B147: Avanzando Equidad de Salud: Latino Cancer Health Equity Research Center." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): B147. http://dx.doi.org/10.1158/1538-7755.disp24-b147.

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Abstract South Texas (STX), spanning from San Antonio to the Texas-Mexico border, includes 25 rural counties, with 96% designated as primary care shortage areas, are notably the nation’s poorest and most medically underserved regions in the United States. Hispanic/Latinos (H/Ls) in the U.S. face challenges related to social determinants of health (SDoH), contributing to disparities in cancer prevention, diagnosis, treatment, and outcomes. H/Ls have higher risks of invasive cancers compared to peers, emphasizing the critical need to address SDoH to mitigate cancer disparities. Addressing these

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Odai-Afotey, Ashley, Ellana Haakenstad, Sunyi Zhang, Bridget A. Neville, Stuart Lipsitz, and Nadine J. McCleary. "Abstract 5939: Feasibility of systemic SDOH collection and associated resource utilization at a large academic cancer center." Cancer Research 82, no. 12_Supplement (2022): 5939. http://dx.doi.org/10.1158/1538-7445.am2022-5939.

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Abstract BACKGROUND: The WHO defines social determinants of health (SDoH) as “the conditions in which people are born, grow, live and age” which includes factors such as housing and food insecurity, employment, and social support and can account for 30-55% of health outcomes. Addressing unmet SDoH needs may reduce interruptions to cancer care caused by ED visits and hospitalizations (EDH). We aimed to determine feasibility of systematic patient-reported SDoH collection at a large academic cancer center and association of unmet SDoH needs with EDH.METHODS: We conducted a cross-sectional analysi

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Alviz, Lesgui, David Tebar-García, Raquel Lopez-Rosa, et al. "Pathogenic Microenvironment from Diabetic–Obese Visceral and Subcutaneous Adipocytes Activating Differentiation of Human Healthy Preadipocytes Increases Intracellular Fat, Effect of the Apocarotenoid Crocetin." Nutrients 13, no. 3 (2021): 1032. http://dx.doi.org/10.3390/nu13031032.

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In diabetes mellitus type 2 (DM2), developed obesity is referred to as diabesity. Implementation of a healthy diet, such as the Mediterranean, prevents diabesity. Saffron is frequently used in this diet because of its bioactive components, such as crocetin (CCT), exhibit healthful properties. It is well known that obesity, defined as an excessive accumulation of fat, leads to cardiometabolic pathology through adiposopathy or hypertrophic growth of adipose tissue (AT).This is related to an impaired adipogenic process or death of adipocytes by obesogenic signals. We aimed to evaluate the effect

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Smith, Alexandria P., Ayesha Ali, Ayako Shimada, et al. "Abstract 5859: Impact of adverse SDOH on cancer knowledge and beliefs: Analysis of a NCI-designated cancer center’s catchment area survey." Cancer Research 82, no. 12_Supplement (2022): 5859. http://dx.doi.org/10.1158/1538-7445.am2022-5859.

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Abstract Background: Social determinants of health (SDOH) are social barriers that stratify health status. Specifically, socioeconomic status, education level, minority and immigration status correlate with higher risk of onset and severity of chronic disease. We sought to understand how SDOH affect a patient’s belief regarding autonomy over cancer risk and outcomes. Methods: Data from the Sidney Kimmel Cancer Center catchment area including Delaware, Montgomery, and Philadelphia Counties in Pennsylvania; Camden and Burlington Counties in New Jersey were queried and analyzed. The survey includ

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Aziz-Bose, Rahela, Yael Flamand, Puja J. Umaretiya, et al. "Abstract B096: Food insecurity and receipt of Supplemental Nutrition Assistance Program (SNAP) benefits among income-eligible US pediatric acute lymphoblastic leukemia patients enrolled on a multi-center clinical trial." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): B096. http://dx.doi.org/10.1158/1538-7755.disp22-b096.

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Abstract Background Food insecurity (FI) is an adverse social determinant of health (SDoH) prevalent among pediatric cancer patients and associated with poorer health outcomes in general pediatrics. Receipt of federal SNAP benefits reduces FI in general pediatrics, and is thus a marker of appropriate resource support to mitigate adverse SDoH. Dana-Farber Cancer Institute (DFCI) Acute Lymphoblastic Leukemia (ALL) Consortium Trial 16-001 is the first pediatric oncology clinical trial to prospectively collect parent-reported SDoH, including income, SNAP receipt, and FI. We investigated whether in

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Zhang, Xinyuan (Cindy), Longgang Zhao, David Vlahov, Yun Chen, Tamar Taddei, and Xuehong Zhang. "Abstract 4939: Social determinants disadvantage score and risk of liver cancer in the All of Us Research Program." Cancer Research 85, no. 8_Supplement_1 (2025): 4939. https://doi.org/10.1158/1538-7445.am2025-4939.

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Abstract Background: Social determinants of health (SDOH) are crucial in shaping health outcomes, yet comprehensive studies that span all key SDOH domains (economic stability, education, healthcare access and quality, neighborhood and built environment, and social and community context) to examine their associations with liver cancer risk are sparse. We developed and validated a Social Determinants Disadvantage Score (SDDS) to address this knowledge gap. Methods: We conducted a cross-sectional analysis of 117, 783 participants from the All of Us Research Program. The SDDS was systematically co

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Adeyemi, Clementine, Louise B. Murphy, Tim Bancroft, et al. "Abstract 7382: Trends in next generation sequencing (NGS) testing by social determinants of health for metastatic cancer patients, 2016-2022." Cancer Research 85, no. 8_Supplement_1 (2025): 7382. https://doi.org/10.1158/1538-7445.am2025-7382.

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Abstract Introduction: Next Generation Sequencing (NGS) testing is a precision medicine tool that uses genomic information from patient tumors to inform treatment decisions and direct patient access to targeted therapies. Social determinants of health (SDOH) partially explain barriers to healthcare access, which can impact clinical outcomes. Real-world studies examining impact of SDOH on receipt of genomic testing are limited. Objective: To examine annual incidence rates (IR) of NGS testing overall and by SDOH indices in endometrial, lung, and colorectal cancer patients. Methods: This retrospe

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Ashing, Kimlin T., Folakemi T. Odedina, Cassandra N. Moore, et al. "Abstract A033: The iCCARE Consortium for Prostate Cancer in Black men: Creating a survivorship care plan for Black prostate cancer survivors." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): A033. http://dx.doi.org/10.1158/1538-7755.disp22-a033.

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Abstract Background: Globally, Black men suffer the greatest prostate cancer (CaP) burden. Blacks are diagnosed more at advanced stages of CaP, greater morbidity and mortality and poorer survivorship outcomes. Blacks are exposed to adverse, discriminatory societal determinants. How these determinants impact the CaP disparities, in particular survivorship and health related quality of life inequities are understudied. Studies examining patient-reported outcomes of Black CaP survivors reveal heightened negative HRQOL sequelae, and depression, family, work and living situation instability due to

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Swaminathan, Padmapriya, McKenna Deaton, Crystal Hattum, et al. "Abstract 6160: Mutational signatures and their associations with social determinants of health." Cancer Research 84, no. 6_Supplement (2024): 6160. http://dx.doi.org/10.1158/1538-7445.am2024-6160.

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Abstract Introduction: Mutational signatures, or unique patterns of genetic mutations due to exogenous and endogenous mutational processes, are being continuously identified through the analysis of cancer patients’ genomes. While cancer research has developed and mortality rates have declined, disparities in cancer outcomes have widened. Social determinants of health (SDOH), such as access to health care, education, and economic stability are essential to addressing health equity. While much research is ongoing regarding the identification and etiology of mutational signatures, little work has

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Cohen, Camryn Mae, Kassandra I. Alcaraz, and Avonne E. Connor. "Abstract LB332: Social determinants of health and telehealth receipt among US cancer survivors." Cancer Research 85, no. 8_Supplement_2 (2025): LB332. https://doi.org/10.1158/1538-7445.am2025-lb332.

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Abstract Background: Following the COVID-19 pandemic, telehealth has risen as a popular alternative to in-person healthcare visits in the United States. Telehealth serves as a promising tool for reducing disparities in access to care, particularly for cancer survivors who experience adverse social conditions and require frequent contact with the healthcare system. Whether experiencing adverse social determinants of health (SDOH) is associated with receipt of telehealth among cancer survivors is unknown. Methods: We utilized cross-sectional data from the National Cancer Institute’s 2022 Health

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Torres, Paola, Carolina Bujanda, Celeste Charchalac-Zapeta, et al. "Abstract A025: Empowering Latinas to obtain genetic services: Comparing precision cancer prevention strategies." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): A025. http://dx.doi.org/10.1158/1538-7755.disp23-a025.

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Abstract Purpose: Precision cancer prevention strategies are critical for addressing the complex interplay of adverse social determinants of health (SDOH) and elevated biological risks for breast cancer (BC) among Latinas and other marginalized communities. FQHC-community-academic partnerships may have particularly high potential for operationalizing these strategies and reducing population-level disparities through enhancing genetic counseling and testing (GCT) and subsequent cascade testing/personalized care. Objective: To present emerging results from a RCT comparing the effectiveness of tw

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Guadamuz, Jenny, Ronac Mamtani, Xiaoliang Wang, et al. "Abstract A049: Racial/ethnic and socioeconomic inequities in clinical trial participation among US community oncology patients, 2011-2021." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): A049. http://dx.doi.org/10.1158/1538-7755.disp22-a049.

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Abstract Introduction: While oncology clinical trials disproportionately recruit from academic medical centers, most patients receive care in the community setting. However, there is limited information regarding clinical trial participation rates, including inequities by race/ethnicity and the social determinants of health (SDoH), in community practices. Here we assessed factors associated with clinical study drug (CSD, proxy for trial participation) receipt among patients diagnosed with 21 common cancers in community practices. Methods: This retrospective study used the nationwide Flatiron H

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Takruri, Lina, Farah Abu Khadra, Toth Akos Levente, and Miklos Banhidi. "Environmental Influence on the Physical Activity and Obesity Rates of the Hungarian Adult Females: A Systematic Review." Hitit Movement Science Journal 1, no. 1 (2024): 28–53. https://doi.org/10.5281/zenodo.14713150.

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Introduction: physical inactivity is insidiously taking over people’s lives. As it interplays with improper dietary habits, obesity rates can have growing incidence. Those outcomes and health practices are influenced by the environment that adult females live at, since they are required to perform main social roles they carry during adulthood. This content analysis aims to analyse how the environment in Hungary influences their lifestyle patterns, health practices and outcomes.Methods and Objectives: the objective of this study is to analyse how social environment affect physical activit

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Kim, Yoonji, Xiaoxi Meng, Jaesung Choi, et al. "Abstract 2260: Social vulnerability and epigenetic signatures in adult survivors of childhood cancer with African ancestry: An epigenome-wide association study." Cancer Research 85, no. 8_Supplement_1 (2025): 2260. https://doi.org/10.1158/1538-7445.am2025-2260.

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Abstract Background: Social determinants of health (SDOH) are increasingly recognized as critical factors in shaping long-term adverse health outcomes among childhood cancer survivors (survivors) because long-lasting toxicities from cancer treatment may be exacerbated by social adversity. Our previous epigenetic study of SDOH primarily focused on survivors of European ancestry, using measures such as educational attainment, personal income, and the Area Deprivation Index. This study aims to enhance understanding of the biological embedding of social adversity in survivors of African ancestry u

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Narra, Vijeth, Alex Krule, Abdul J. Zakkar, et al. "Abstract 4925: Social determinant predictors of lung cancer incidence in diverse urban populations." Cancer Research 85, no. 8_Supplement_1 (2025): 4925. https://doi.org/10.1158/1538-7445.am2025-4925.

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Abstract Background: Lung cancer is the leading cause of cancer-related mortality globally. While screening and predictive analytics provide insights into its pathogenesis, the role of social determinants of health (SDOH), particularly in urban U.S. populations, is unexplored at the individual level. This study examines associations between SDOH factors and lung cancer within Chicago. Methods: An IRB-approved protocol was used to build a retrospective cohort of 11, 154 patients (60% African American [AA], 30% White, 10% Other) from the University of Illinois Health System. Inclusion criteria f

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Sathe, Claire, David DeStephano, Anita Gul, et al. "Abstract PO1-10-03: Prevalence of and Factors Associated with Food Insecurity and Other Adverse Social Determinants of Health Among Breast Oncology Patients." Cancer Research 84, no. 9_Supplement (2024): PO1–10–03—PO1–10–03. http://dx.doi.org/10.1158/1538-7445.sabcs23-po1-10-03.

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Abstract Background: Social determinants of health (SDOH), the non-medical factors that influence health status, have a profound impact on breast cancer (BC) outcomes and contribute to survival disparities. Food insecurity (FI), defined as a lack of consistent access to adequate food resources, is a modifiable SDOH associated with treatment disruptions, medication nonadherence, and decreased quality of life. To identify at-risk patients and inform future interventions, we implemented SDOH screening of patients seen in breast oncology clinic at our urban academic medical center. Methods: Screen

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Sleiman, Marcelo, Tara Suntum, Nina Kadan-Lottick, et al. "Abstract B067: A mixed-methods health services analysis of disparities and social vulnerabilities in childhood cancer survivors’ long-term follow-up care." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): B067. http://dx.doi.org/10.1158/1538-7755.disp24-b067.

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Abstract Pediatric cancer affects &gt;15,000 US children annually. Treatment advances have led to an increase in those surviving the disease, and these patients must be managed to control their long-term comorbidities. Unfortunately, a majority are nonadherent to post-treatment care guidelines and become lost to follow-up. This is especially true for those from underserved backgrounds, including survivors who are Black and Latine. To help understand this disparity, we studied the organization and delivery of pediatric cancer survivorship care at an urban comprehensive cancer center. Resear

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Austin, Jessica D., Todd Huschka, Amelia Barwise, Megan Allyse, and Sean Phelan. "Abstract A077: The role of social determinants of health on beliefs around the benefits of clinical trials." Cancer Epidemiology, Biomarkers & Prevention 32, no. 12_Supplement (2023): A077. http://dx.doi.org/10.1158/1538-7755.disp23-a077.

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Abstract Background: Individuals from diverse racial/ethnic and disadvantaged backgrounds are underrepresented in cancer clinical trials, compounding the difficulty of adequately understanding, addressing, and reversing health inequities. Social determinants of health (SDOH) factors likely contribute to disparities in cancer trial enrollment. While the presence of SDOH has shown to be associated with clinical trial participation, few studies have explored the role of SDOH in shaping beliefs around the benefits of clinical trials. Thus, this study aims to identify SDOH factors associated with b

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Lu, Kun-Han, Yi Xiao, Aamna Akhtar, et al. "Abstract 4971: Predicting lung cancer screening adherence among underserved and minoritized communities using social determinants and neighborhood factors." Cancer Research 85, no. 8_Supplement_1 (2025): 4971. https://doi.org/10.1158/1538-7445.am2025-4971.

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Abstract Purpose: Lung cancer screening (LCS) lowers cancer mortality if individuals adhere to annual scans. Minoritized communities have significantly lower adherence to LCS than non-Hispanic whites. The influence of social determinants of health (SDOH) on these disparate adherence rates are rarely evaluated. The aim of this study is to develop a machine learning (ML) model that integrates individual and neighborhood level SDOH to predict which minoritized individuals are at risk of LCS non-adherence. Methods: A total of 168 participants with high-risk smoking histories who underwent their fi

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Barnard, Mollie, Bo Qin, Marc A. Emerson, et al. "Abstract P3-06-06: Associations between social drivers of health and breast cancer stage at diagnosis among US Black women." Clinical Cancer Research 31, no. 12_Supplement (2025): P3–06–06—P3–06–06. https://doi.org/10.1158/1557-3265.sabcs24-p3-06-06.

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Abstract Introduction: In the US, Black women who are diagnosed with breast cancer experience disproportionately high disease-specific mortality. This is, in part, because US Black women are more likely to be diagnosed with advanced-stage breast cancer. We sought to understand how social drivers of health (SDOH) relate to breast cancer diagnostic stage among US Black women. Methods: This analysis included self-identified Black or African American women diagnosed with breast cancer who were participants in the Black Women’s Health Study (BWHS; n=1,777), the Women’s Circle of Health Study (WCHS;

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Jones, Nehanda, Adam Blair, Elizabeth Lipschultz, Jacob Koskimaki, Brooke Smither, and Robert Miller. "Abstract P3-03-12: Social Determinants of Health (SDOH) and Z Code Utilization among Patients with Breast Cancer (BC)." Clinical Cancer Research 31, no. 12_Supplement (2025): P3–03–12—P3–03–12. https://doi.org/10.1158/1557-3265.sabcs24-p3-03-12.

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Abstract Background: Previous studies show that SDOH play an important role in BC stage, treatment, and outcomes. Disparities in BC overall survival (OS) by SDOH are well documented. Z codes were introduced into International Classification of Diseases, 10th edition in 2015 to identify reasons for clinical encounters when circumstances other than a disease or injury are recorded as diagnoses, but uptake has been slow. Herein we report Z codes Z55 – Z65, which specifically identify SDOH impacting health care utilization, for BC patients (pts) in CancerLinQ (CLQ). Methods CLQ is a health data pl

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Burke, Sara, Constantine Daskalakis, Khaldoun Hamade, Christopher McNair, and Nicole Simone. "Abstract B005: Using EMR-based SOGI data collection to identify disparities in sexual and gender minority patients with cancer." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): B005. http://dx.doi.org/10.1158/1538-7755.disp24-b005.

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Abstract Purpose/Objectives: Sexual and gender minority (SGM) patients have been suggested to face disparities in cancer screening and outcomes. Despite this, a large barrier to improving care for this population is the lack of sexual orientation and gender identity (SOGI) data available in surveillance, research, and clinical settings. This study aimed to create integrated datasets containing SOGI and clinical data from electronic medical records (EMR) to better characterize SGM cancer patients with the goal of narrowing disparities and improving cancer care by tailoring to the needs of this

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Plonski, Noel-Marie, Cheng Chen, Qian Dong, et al. "Abstract 3503: Racial disparity and roles of social determinants of health in epigenetic age acceleration among survivors of childhood cancer." Cancer Research 83, no. 7_Supplement (2023): 3503. http://dx.doi.org/10.1158/1538-7445.am2023-3503.

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Abstract Our published studies demonstrated that epigenetic age acceleration (EAA) is significantly higher in childhood cancer survivors than non-cancer controls. Additionally, EAA is associated with germline genetics, cancer treatments, unfavorable health behaviors, and chronic health conditions. However, our previous studies were limited to non-Hispanic whites (NHW). We aimed to investigate and compare the EAA between non-Hispanic blacks (NHB) and NHW, and evaluate the contribution of social determinants of health (SDOH) to potential racial disparity in EAA. Methylation profiling was generat

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Odedina, Folakemi, Che Ngufor, Arnold Merriweather, et al. "Abstract B028: A point of prostate cancer diagnosis (PPCD) Virtual Robot Assistant (ViRA) intervention for newly diagnosed Black men: An iCCaRE consortium for prostate cancer in Black men project." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): B028. http://dx.doi.org/10.1158/1538-7755.disp22-b028.

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Abstract Background: To date, the disparate burden of prostate cancer (CaP) in Black men (BM) is still poorly understood. More disconcerting is the limited access to effective, culturally tailored behavioral interventions to support BM diagnosed with CaP, especially at the point of prostate cancer diagnosis (PPCD). From the PPCD, the transition to CaP survivorship can be mentally and physically trying, especially for those lacking emotional and financial support. It is important to provide psycho-oncology support, address social determinants of health (SDOH) and make emotional support availabl

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Bournigal-Feliciano, Mariela, Marievelisse Soto-Salgado, Hilmaris Centeno-Girona, et al. "Abstract 2245: Awareness and participation in cancer-related clinical trials among gastrointestinal cancer survivors." Cancer Research 84, no. 6_Supplement (2024): 2245. http://dx.doi.org/10.1158/1538-7445.am2024-2245.

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Abstract Despite significant advances in cancer prevention, early detection, and treatment, there is a persistent disparity in cancer outcomes between diverse racial/ethnic groups and medically underserved populations in the United States (US). The underrepresentation of non-white racial/ethnic groups in clinical trials (CTs) poses a critical challenge to cancer research and effective care delivery. The Hispanic/Latino population is one of the fastest-growing ethnic groups in the US and has a high rate of gastrointestinal (GI) cancer. Although Hispanics/Latinos comprise 18.5% of the US populat

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Centeno-Girona, Hilmaris, Marievelisse Soto-Salgado, Stephanie Cameron-Maldonado, et al. "Abstract 4918: Impact of social drivers of health on clinical trial knowledge among Hispanic/Latino and Black cancer survivors." Cancer Research 85, no. 8_Supplement_1 (2025): 4918. https://doi.org/10.1158/1538-7445.am2025-4918.

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Introduction: Despite significant advancements in cancer treatment, disparities in clinical trial (CT) participation persist among minority populations, such as Hispanic/Latino (H/L) and Black women (BW). Social drivers of health (SDoH) can influence health outcomes and health care decisions, like CT participation. This study assessed the association between SDoH and CT knowledge among H/L and BW cancer survivors in Puerto Rico and in Virginia, United States. Methodology: This cross-sectional study included H/L gastrointestinal (GI) cancer survivors from Puerto Rico and BW with breast or gynec

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Aklilu, Bathsheba, Erica Tate, and Cathy Samayoa. "Abstract 4976: Examining the association between chronic inflammation, stress, and resilience factors among diverse breast cancer survivors using the NIH All of Us dataset." Cancer Research 85, no. 8_Supplement_1 (2025): 4976. https://doi.org/10.1158/1538-7445.am2025-4976.

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Abstract Breast cancer disparities exist by race and ethnicity, including disparities in age at diagnosis, quality of life, and health outcomes. These disparities may be influenced by chronic stress, exacerbated by unique challenges that extend beyond disease management, such as the effects of psychosocial stress and social determinants of health (SDOH) on chronic inflammation. Elevated C-reactive protein (CRP) levels, a marker of chronic inflammation, are implicated in worse health outcomes. Understanding how stress and SDOH interact to influence CRP and other inflammatory biomarkers is criti

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Velazquez-Villarreal, Enrique I., and Ei-Wen Yang. "Abstract 1115: PM-AI agent: A conversational artificial intelligence system for precision medicine and advancing health equity through integrative clinical, genomic and social determinants of health data analysis." Cancer Research 85, no. 8_Supplement_1 (2025): 1115. https://doi.org/10.1158/1538-7445.am2025-1115.

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Abstract Introduction: The integration of clinical, genomic, and social determinants of health (SDoH) data is essential for advancing precision medicine. However, significant challenges remain due to the complexity of cancer research workflows, the technical expertise required, and the pressing need to address cancer health disparities. To overcome these barriers, we developed the Precision Medicine AI Agent (PM-AI)—an innovative conversational AI system that enables users to conduct integrative data analyses through natural language inquiries. Methods: PM-AI leverages large language models (L

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Mehta, Akhil, Eric Lau, Gayathri Nagaraj, and Hamid Mirshahidi. "Abstract 3662: Association of US county-level social vulnerability index (SVI) with breast and colon cancer screening rates." Cancer Research 82, no. 12_Supplement (2022): 3662. http://dx.doi.org/10.1158/1538-7445.am2022-3662.

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Abstract Introduction: Whether social determinants of health (SDOH) affect US breast and colon cancer screening rates remains unclear. That said, in 2011 the CDC began recording a social vulnerability index (SVI) for all US counties. SVI was designed to capture four SDOH: socioeconomic status (SES), household composition and disability, minority status and language, and housing type and transportation. This retrospective study sought to determine the association of county-level SVI with breast and colon cancer screening rates. Methods: We used publicly available data from the CDC 2018 SVI data

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Tang, Weizhou, Yanyuan Wu, and Jaydutt Vadgama. "Abstract B150: Social determinants of health and comorbidities increasing inflammation cytokines related to breast cancer in African American and Latinx women." Cancer Epidemiology, Biomarkers & Prevention 33, no. 9_Supplement (2024): B150. http://dx.doi.org/10.1158/1538-7755.disp24-b150.

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Abstract Introduction: Comorbidities such as obesity, Type-2 diabetes (T2D), and hypertension (HTN) are highly prevalent among under-resourced African Americans (AA) and Latinx, and they are associated with breast cancer (BC) risks and outcomes. Social determinants of health (SDOH) also have been found related to BC incidence, stage, and survival. In addition, elevated inflammatory cytokines may be an underlying factor in comorbidities that contribute to tumorigenesis and adverse cancer outcomes. Limited research has been conducted to explore the process and associations among SDOH, comorbidit

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Islam, Jessica Yasmine, Jennifer McGee, Yi Guo, et al. "Abstract 744: Treatment inequities among patients diagnosed with Hodgkin's lymphoma with and without HIV (2018-2019): an analysis of the US National Cancer Database." Cancer Research 83, no. 7_Supplement (2023): 744. http://dx.doi.org/10.1158/1538-7445.am2023-744.

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Abstract Background: People living with HIV (PLWH) with Hodgkin’s lymphoma(HL) have similar response and survival rates to people without HIV when standard of care therapies are given. However, PLWH with HL are less likely to receive cancer treatment for unclear reasons. Our objective was to examine the role of social determinants of health(SDOH) with non-receipt of cancer treatment among PLWH with HL. Methods: Using the U.S. National Cancer Database, we identified 11,517 persons aged 18-90 years, diagnosed with HL (ICD-O-3 codes; C770-779) between 2018-2019. Most patients were diagnosed with

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Odedina, Folakemi T., Che Ngufor, Arnold Merriweather, et al. "Abstract 2230: Connecting Black men to point of prostate cancer diagnosis (PPCD) support using precision intervention based on Virtual Reality Assistant (ViRA)." Cancer Research 84, no. 6_Supplement (2024): 2230. http://dx.doi.org/10.1158/1538-7445.am2024-2230.

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Abstract Background: The point of prostate cancer (CaP) diagnosis (PPCD) instantly leads to a life changing experience for Black men, with diverse emotional reactions that includes fear, denial, overwhelmingness, cancer fatalism etc. Black men diagnosed with CaP expressed several needs at the PPCD, including time to reflect on the diagnosis, being comfortable, emotional support, psycho-oncology support and social determinants of health (SDOH) navigation. Given that Black men are diverse in terms of their needs at the PPCD, precision intervention is needed to support them. Aim: The aim was to d

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Iasiello, John A., Arvind Rajan, Emmanuel Zervos, Alexander A. Parikh, and Rebecca A. Snyder. "Abstract B105: Patient-reported access to telehealth: An important and unmeasured social determinant of health." Cancer Epidemiology, Biomarkers & Prevention 32, no. 1_Supplement (2023): B105. http://dx.doi.org/10.1158/1538-7755.disp22-b105.

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Abstract Background: The recent COVID-19 pandemic expanded opportunities for remote oncology telehealth visits. However, reliable internet connectivity, digital literacy, and patient comfort with virtual medical visits may differ among patients, especially socially disadvantaged groups. The primary aim of this study was to identify patient demographics and social determinants of health (SDOH) which might limit access to remote telehealth services. Methods: First, a retrospective analysis was performed of composite administrative data of all patient visits to a large regional cancer center over

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Friedler, Haley, Meghan Tierney, Melinda Baker, et al. "Abstract PO5-19-04: EVOLVE: An Ambispective, Patient-Centered, Real-World Early-Stage Breast Cancer Study in the United States." Cancer Research 84, no. 9_Supplement (2024): PO5–19–04—PO5–19–04. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-19-04.

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Abstract Background: While survival for patients with early breast cancer (eBC) has greatly improved with earlier detection and modern treatments, the risk of recurrence and long-term/late treatment-related adverse events (AEs) remain concerns for many patients. Contemporary real-world data are needed to understand current diagnostic pathways, treatment patterns and toxicities, quality of life, and patient experience to better characterize eBC care and knowledge gaps and establish important hypotheses to test in prospective trials, with the ultimate goal to improve both treatment and outcomes

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