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Journal articles on the topic 'Seam cells'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Koh, Kyunghee, and Joel H. Rothman. "ELT-5 and ELT-6 are required continuously to regulate epidermal seam cell differentiation and cell fusion inC. elegans." Development 128, no. 15 (2001): 2867–80. http://dx.doi.org/10.1242/dev.128.15.2867.

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The C. elegans epidermis is a simple epithelium comprised of three major cell types, the seam, syncytial and P cells. While specification of all major epidermal cells is known to require the ELT-1 GATA transcription factor, little is known about how the individual epidermal cell types are specified. We report that elt-5 and -6, adjacent genes encoding GATA factors, are essential for the development of the lateral epidermal cells, the seam cells. Inhibition of elt-5 and -6 function by RNA-mediated interference results in penetrant late embryonic and early larval lethality. Seam cells in affecte

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2

Austin, J., and C. Kenyon. "Cell contact regulates neuroblast formation in the Caenorhabditis elegans lateral epidermis." Development 120, no. 2 (1994): 313–23. http://dx.doi.org/10.1242/dev.120.2.313.

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A single line of epidermal seam cells lies along each side of the nematode C. elegans. During normal development, one of these cells, V5, produces a neuroblast that will give rise to a sensory structure, the postdeirid. If seam cells located either anterior or posterior to V5 are ablated however, this neuroblast formation is blocked. Because of this requirement for the presence of adjacent seam cells, we have asked whether V5's ability to produce a neuroblast depends on direct contact with its seam cell neighbors. We find that direct contact between seam cells is required for commitment to neu

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3

Brabin, Charles, and Alison Woollard. "Finding a niche for seam cells?" Worm 1, no. 2 (2012): 107–11. http://dx.doi.org/10.4161/worm.19417.

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4

Hintze, Mark, Sneha L. Koneru, Sophie P. R. Gilbert, Dimitris Katsanos, Julien Lambert, and Michalis Barkoulas. "A Cell Fate Switch in the Caenorhabditis elegans Seam Cell Lineage Occurs Through Modulation of the Wnt Asymmetry Pathway in Response to Temperature Increase." Genetics 214, no. 4 (2020): 927–39. http://dx.doi.org/10.1534/genetics.119.302896.

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Populations often display consistent developmental phenotypes across individuals despite inevitable biological stochasticity. Nevertheless, developmental robustness has limits, and systems can fail upon change in the environment or the genetic background. We use here the seam cells, a population of epidermal stem cells in Caenorhabditis elegans, to study the influence of temperature change and genetic variation on cell fate. Seam cell development has mostly been studied so far in the laboratory reference strain (N2), grown at 20° temperature. We demonstrate that an increase in culture temperat

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Gidlöf, Cecilia, Mikael Dohlsten, Peter Lando, Terje Kalland, Christer Sundström, and Thomas H. Tötterman. "A Superantigen-Antibody Fusion Protein for T-Cell Immunotherapy of Human B-Lineage Malignancies." Blood 89, no. 6 (1997): 2089–97. http://dx.doi.org/10.1182/blood.v89.6.2089.

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Abstract The bacterial superantigen staphylococcal enterotoxin A (SEA) is an efficient activator of cytotoxic T cells when presented on major histocompatibility complex (MHC) class II molecules of target cells. Our previous studies showed that such SEA-directed T cells efficiently lysed chronic B-lymphocytic leukemia (B-CLL) cells. Next, we made a mutated SEA–protein A (SEAm-PA) fusion protein with more than 1,000-fold reduced binding affinity for MHC class II compared with native SEA. The fusion protein was successfully used to direct T cells to B-CLL cells coated with different B lineage–dir

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Terns, Rebecca M., Peggy Kroll-Conner, Jiangwen Zhu, Sooyoun Chung, and Joel H. Rothman. "A Deficiency Screen for Zygotic Loci Required for Establishment and Patterning of the Epidermis in Caenorhabditis elegans." Genetics 146, no. 1 (1997): 185–206. http://dx.doi.org/10.1093/genetics/146.1.185.

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To identify genomic regions required for establishment and patterning of the epidermis, we screened 58 deficiencies that collectively delete at least ∼67% of the Caenorhabditis elegans genome. The epidermal pattern of deficiency homozygous embryos was analyzed by examining expression of a marker specific for one of the three major epidermal cell types, the seam cells. The organization of the epidermis and internal organs was also analyzed using a monoclonal antibody specific for epithelial adherens junctions. While seven deficiencies had no apparent effect on seam cell production, 21 were foun

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7

Carette, M. J., and M. W. Ferguson. "The fate of medial edge epithelial cells during palatal fusion in vitro: an analysis by DiI labelling and confocal microscopy." Development 114, no. 2 (1992): 379–88. http://dx.doi.org/10.1242/dev.114.2.379.

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Fusion of bilateral shelves, to form the definitive mammalian secondary palate, is critically dependent on removal of the medial edge cells that constitute the midline epithelial seam. Conflicting views suggest that programmed apoptotic death or epithelial-mesenchymal transformation of these cells is predominantly involved. Due in part to the potentially ambiguous interpretation of static images and the notable absence of fate mapping studies, the process by which this is achieved has, however, remained mechanistically equivocal. Using an in vitro mouse model, we have selectively labelled pala

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8

Griffith, C. M., and E. D. Hay. "Epithelial-mesenchymal transformation during palatal fusion: carboxyfluorescein traces cells at light and electron microscopic levels." Development 116, no. 4 (1992): 1087–99. http://dx.doi.org/10.1242/dev.116.4.1087.

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During the fusion of rodent embryo palatal shelves, the cells of the outer epithelial layer slough off, allowing the cells of the medial edge basal layer to form a midline seam that undergoes epithelial-mesenchymal transformation, as judged by electron microscopy and immunohistochemistry. In this study, we analyze the fate of the transformed cells using a lipid soluble dye to label the medial edge epithelium in situ. Prefusion E14 mouse palates were exposed in vitro or in vivo to a fluoresceinated lipid soluble marker, carboxydichlorofluorescein diacetate succinimidyl ester (CCFSE), which loca

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9

Bettinger, J. C., K. Lee, and A. E. Rougvie. "Stage-specific accumulation of the terminal differentiation factor LIN-29 during Caenorhabditis elegans development." Development 122, no. 8 (1996): 2517–27. http://dx.doi.org/10.1242/dev.122.8.2517.

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The Caenorhabditis elegans gene lin-29 is required for the terminal differentiation of the lateral hypodermal seam cells during the larval-to-adult molt. We find that lin-29 protein accumulates in the nuclei of these cells, consistent with its predicted role as a zinc finger transcription factor. The earliest detectable LIN-29 accumulation in seam cell nuclei is during the last larval stage (L4), following the final seam cell division, which occurs during the L3-to-L4 molt. LIN-29 accumulates in all hypodermal nuclei during the L4 stage. The time of LIN-29 appearance in the hypodermis is contr

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10

Kikkawa, M., T. Ishikawa, T. Nakata, T. Wakabayashi, and N. Hirokawa. "Direct visualization of the microtubule lattice seam both in vitro and in vivo." Journal of Cell Biology 127, no. 6 (1994): 1965–71. http://dx.doi.org/10.1083/jcb.127.6.1965.

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Microtubules are constructed from alpha- and beta-tubulin heterodimers that are arranged into protofilaments. Most commonly there are 13 or 14 protofilaments. A series of structural investigations using both electron microscopy and x-ray diffraction have indicated that there are two potential lattices (A and B) in which the tubulin subunits can be arranged. Electron microscopy has shown that kinesin heads, which bind only to beta-tubulin, follow a helical path with a 12-nm pitch in which subunits repeat every 8-nm axially, implying a primarily B-type lattice. However, these helical symmetry pa

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11

Schmitz, Patrick. "Comparative Study on Pulsed Laser Welding Strategies for Contacting Lithium-Ion Batteries." Advanced Materials Research 1140 (August 2016): 312–19. http://dx.doi.org/10.4028/www.scientific.net/amr.1140.312.

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The transition towards renewable energy implicates more decentralized and time-dependent ways of energy generation. In order to deal with the resulting fluctuation in energy supply, local storage systems are necessary. Larger systems may consist of thousands of battery cells. Therefore, the reliable interconnection between the individual battery cells is the basic prerequisite for the production of these systems. It has been demonstrated that laser beam welding is a suitable process for the contacting of batteries. However, due to the high requirements regarding the heat input and the reproduc

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12

Ke, Chen-Yeh, Hua-Hsuan Mei, Fen-Hwa Wong, and Lun-Jou Lo. "IRF6 and TAK1 coordinately promote the activation of HIPK2 to stimulate apoptosis during palate fusion." Science Signaling 12, no. 593 (2019): eaav7666. http://dx.doi.org/10.1126/scisignal.aav7666.

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Cleft palate is a common craniofacial defect caused by a failure in palate fusion. The palatal shelves migrate toward one another and meet at the embryonic midline, creating a seam. Transforming growth factor–β3 (TGF-β3)–induced apoptosis of the medial edge epithelium (MEE), the cells located along the seam, is required for completion of palate fusion. The transcription factor interferon regulatory factor 6 (IRF6) promotes TGF-β3–induced MEE cell apoptosis by stimulating the degradation of the transcription factor ΔNp63 and promoting the expression of the gene encoding the cyclin-dependent kin

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13

Ren, Haiyan, and Hong Zhang. "Wnt signaling controls temporal identities of seam cells in Caenorhabditis elegans." Developmental Biology 345, no. 2 (2010): 144–55. http://dx.doi.org/10.1016/j.ydbio.2010.07.002.

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14

Hunter, C. P., J. M. Harris, J. N. Maloof, and C. Kenyon. "Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling." Development 126, no. 4 (1999): 805–14. http://dx.doi.org/10.1242/dev.126.4.805.

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In Caenorhabditis elegans males, a row of epidermal precursor cells called seam cells generates a pattern of cuticular alae in anterior body regions and neural sensilla called rays in the posterior. The Hox gene mab-5 is required for two posterior seam cells, V5 and V6, to generate rays. In mab-5 mutant males, V5 and V6 do not generate sensory ray lineages but instead generate lineages that lead to alae. Here we show that two independent regulatory pathways can activate mab-5 expression in the V cells. First, the caudal homolog pal-1 turns on mab-5 in V6 during embryogenesis. Second, a Wnt sig

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15

Hanna-Rose, W., and M. Han. "COG-2, a sox domain protein necessary for establishing a functional vulval-uterine connection in Caenorhabditis elegans." Development 126, no. 1 (1999): 169–79. http://dx.doi.org/10.1242/dev.126.1.169.

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In screens for mutants defective in vulval morphogenesis, multiple mutants were isolated in which the uterus and the vulva fail to make a proper connection. We describe five alleles that define the gene cog-2, for connection of gonad defective. To form a functional connection between the vulva and the uterus, the anchor cell must fuse with the multinucleate uterine seam cell, derived from uterine cells that adopt a (pi) lineage. In cog-2 mutants, the anchor cell does not fuse to the uterine seam cell and, instead, remains at the apex of the vulva, blocking the connection between the vulval and

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16

Wrischnik, L. A., and C. J. Kenyon. "The role of lin-22, a hairy/enhancer of split homolog, in patterning the peripheral nervous system of C. elegans." Development 124, no. 15 (1997): 2875–88. http://dx.doi.org/10.1242/dev.124.15.2875.

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In C. elegans, six lateral epidermal stem cells, the seam cells V1-V6, are located in a row along the anterior-posterior (A/P) body axis. Anterior seam cells (V1-V4) undergo a fairly simple sequence of stem cell divisions and generate only epidermal cells. Posterior seam cells (V5 and V6) undergo a more complicated sequence of cell divisions that include additional rounds of stem cell proliferation and the production of neural as well as epidermal cells. In the wild type, activity of the gene lin-22 allows V1-V4 to generate their normal epidermal lineages rather than V5-like lineages. lin-22 a

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17

Sun, D., C. R. Vanderburg, G. S. Odierna, and E. D. Hay. "TGFbeta3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro." Development 125, no. 1 (1998): 95–105. http://dx.doi.org/10.1242/dev.125.1.95.

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Epithelial-mesenchymal transformation plays an important role in the disappearance of the midline line epithelial seam in rodent palate, leading to confluence of the palate. The aim of this study was to test the potential of the naturally cleft chicken palate to become confluent under the influence of growth factors, such as TGFbeta3, which are known to promote epithelial-mesenchymal transformation. After labeling medial edge epithelia with carboxyfluorescein, palatal shelves (E8-9) with or without beak were dissected and cultured on agar gels. TGFbeta1, TGFbeta2 or TGFbeta3 was added to the c

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18

Nawshad, Ali, та Elizabeth D. Hay. "TGFβ3 signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development". Journal of Cell Biology 163, № 6 (2003): 1291–301. http://dx.doi.org/10.1083/jcb.200306024.

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Epithelial mesenchymal transformation (EMT) of the medial edge epithelial (MEE) seam creates palatal confluence. This work aims to elucidate the molecular mechanisms by which TGFβ3 brings about palatal seam EMT. We collected mRNA for PCR analysis from individual transforming MEE cells by laser microdissection techniques and demonstrated that TGFβ3 stimulates lymphoid-enhancing factor 1 (LEF1) mRNA synthesis in MEE cells. We show with antisense β-catenin oligonucleotides that up-regulated LEF1 is not activated by β-catenin in palate EMT. We ruled out other TGFβ3 targets, such as RhoA and MEK1/2

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19

Nakajima, Akira, Charles F. Shuler, Alexander Gulka та Jun-ichi Hanai. "TGF-β Signaling and the Epithelial-Mesenchymal Transition during Palatal Fusion". International Journal of Molecular Sciences 19, № 11 (2018): 3638. http://dx.doi.org/10.3390/ijms19113638.

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Signaling by transforming growth factor (TGF)-β plays an important role in development, including in palatogenesis. The dynamic morphological process of palatal fusion occurs to achieve separation of the nasal and oral cavities. Critically and specifically important in palatal fusion are the medial edge epithelial (MEE) cells, which are initially present at the palatal midline seam and over the course of the palate fusion process are lost from the seam, due to cell migration, epithelial-mesenchymal transition (EMT), and/or programed cell death. In order to define the role of TGF-β signaling du

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Gholami, Omid, Mohsen Shakeri, S. Javad Imen, and Hamed Jamshidi Aval. "Small‐scale resistance seam welding of stainless steel bipolar plates of PEM fuel cells." International Journal of Energy Research 45, no. 9 (2021): 13822–35. http://dx.doi.org/10.1002/er.6715.

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21

Nam, Seunghee, Yun-Hye Jin, Qing-Lin Li, et al. "Expression Pattern, Regulation, and Biological Role of Runt Domain Transcription Factor, run, in Caenorhabditis elegans." Molecular and Cellular Biology 22, no. 2 (2002): 547–54. http://dx.doi.org/10.1128/mcb.22.2.547-554.2002.

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ABSTRACT The Caenorhabditis elegans run gene encodes a Runt domain factor. Runx1, Runx2, and Runx3 are the three known mammalian homologs of run. Runx1, which plays an essential role in hematopoiesis, has been identified at the breakpoint of chromosome translocations that are responsible for human leukemia. Runx2 plays an essential role in osteogenesis, and inactivation of one allele of Runx2 is responsible for the human disease cleidocranial dysplasia. To understand the role of run in C. elegans, we used transgenic run::GFP reporter constructs and a double-stranded RNA-mediated interference m

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Газазян, M. Gazazyan, Перепелова, et al. "Myometrium reaction on implantation of polypropylene mesh protheses in experiment." Journal of New Medical Technologies 22, no. 3 (2015): 62–66. http://dx.doi.org/10.12737/13301.

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The article is devoted to the study of the problem of myometrium reaction on implantation of polypropylene mesh prostheses in uterine suture strengthening. Experimental studies have found in animals after strengthening the seam on the uterus polypropylene mesh implant following complications in the postoperative period, such as: bruises, seroma seam and deformation of the uterus. These complications occurred significantly more often than when suturing the incision of the uterus row of blanket stitch. In the evaluation of adhesions, the statistically significant differences in the studied group

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Margalit, Ayelet, Esther Neufeld, Naomi Feinstein, Katherine L. Wilson, Benjamin Podbilewicz, and Yosef Gruenbaum. "Barrier to autointegration factor blocks premature cell fusion and maintains adult muscle integrity in C. elegans." Journal of Cell Biology 178, no. 4 (2007): 661–73. http://dx.doi.org/10.1083/jcb.200704049.

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Barrier to autointegration factor (BAF) binds double-stranded DNA, selected histones, transcription regulators, lamins, and LAP2–emerin–MAN1 (LEM) domain proteins. During early Caenorhabditis elegans embryogenesis, BAF-1 is required to organize chromatin, capture segregated chromosomes within the nascent nuclear envelope, and assemble lamin and LEM domain proteins in reforming nuclei. In this study, we used C. elegans with a homozygous deletion of the baf-1 gene, which survives embryogenesis and larval stages, to report that BAF-1 regulates maturation and survival of the germline, cell migrati

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Pungchanchaikul, P., M. Gelbier, P. Ferretti, and A. Bloch-Zupan. "Gene Expression during Palate Fusion in vivo and in vitro." Journal of Dental Research 84, no. 6 (2005): 526–31. http://dx.doi.org/10.1177/154405910508400608.

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Failure of secondary palate fusion during embryogenesis is a cause of cleft palate. Disappearance of the medial epithelial seam (MES) is required to allow merging of the mesenchyme from both palatal shelves. This involves complex changes of the medial edge epithelial (MEE) cells and surrounding structures that are controlled by several genes whose spatio-temporal expression is tightly regulated. We have carried out morphological analyses and used a semi-quantitative RT-PCR technique to evaluate whether morphological changes and modulation in the expression of putative key genes, such as twist,

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Mueller, Cristian. "Application of lean manufacturing principles to coal seam gas production." APPEA Journal 50, no. 2 (2010): 732. http://dx.doi.org/10.1071/aj09096.

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Themes covered: why lean; how lean manufacturing aligns with our business; the areas of focus for lean production; early results; and, the expected rollout going forward. This paper examines the application and alignment of lean manufacturing principles to CSG production at Arrow Energy. Arrow Energy is a vertically integrated energy provider with a focus on exploration and production of CSG. Implementation of lean manufacturing is a critical success factor for Arrow to deliver on its aggressive expansion targets. The lean manufacturing philosophy is not a new concept. Pioneered by Toyota, lea

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Gorrepati, Lakshmi, Michael W. Krause, Weiping Chen, Thomas M. Brodigan, Margarita Correa-Mendez, and David M. Eisenmann. "Identification of Wnt Pathway Target Genes Regulating the Division and Differentiation of Larval Seam Cells and Vulval Precursor Cells in Caenorhabditis elegans." G3: Genes|Genomes|Genetics 5, no. 8 (2015): 1551–66. http://dx.doi.org/10.1534/g3.115.017715.

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Harandi, Omid F., and Victor R. Ambros. "Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans." Proceedings of the National Academy of Sciences 112, no. 3 (2015): E287—E296. http://dx.doi.org/10.1073/pnas.1422852112.

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Transitions between asymmetric (self-renewing) and symmetric (proliferative) cell divisions are robustly regulated in the context of normal development and tissue homeostasis. To genetically assess the regulation of these transitions, we used the postembryonic epithelial stem (seam) cell lineages of Caenorhabditis elegans. In these lineages, the timing of these transitions is regulated by the evolutionarily conserved heterochronic pathway, whereas cell division asymmetry is conferred by a pathway consisting of Wnt (Wingless) pathway components, including posterior pharynx defect (POP-1)/TCF, A

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Gravato-Nobre, Maria J., Dave Stroud, Delia O'Rourke, Creg Darby, and Jonathan Hodgkin. "Glycosylation Genes Expressed in Seam Cells Determine Complex Surface Properties and Bacterial Adhesion to the Cuticle ofCaenorhabditis elegans." Genetics 187, no. 1 (2010): 141–55. http://dx.doi.org/10.1534/genetics.110.122002.

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Katori, Yukio, Shunichi Shibata, Tetsuaki Kawase, Baik Hwan Cho, and Gen Murakami. "Transient Appearance of Tyrosine Hydroxylase Immunoreactive Cells in the Midline Epithelial Seam of the Human Fetal Secondary Palate." Cleft Palate-Craniofacial Journal 49, no. 4 (2012): 414–24. http://dx.doi.org/10.1597/10-121.

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Gleason, Julie E., and David M. Eisenmann. "Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development." Developmental Biology 348, no. 1 (2010): 58–66. http://dx.doi.org/10.1016/j.ydbio.2010.09.005.

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Huang, Xinxin, E. Tian, Yanhua Xu, and Hong Zhang. "The C. elegans engrailed homolog ceh-16 regulates the self-renewal expansion division of stem cell-like seam cells." Developmental Biology 333, no. 2 (2009): 337–47. http://dx.doi.org/10.1016/j.ydbio.2009.07.005.

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Hollatz, Sören, Sebastian Kremer, Cem Ünlübayir, Dirk Uwe Sauer, Alexander Olowinsky, and Arnold Gillner. "Electrical Modelling and Investigation of Laser Beam Welded Joints for Lithium-Ion Batteries." Batteries 6, no. 2 (2020): 24. http://dx.doi.org/10.3390/batteries6020024.

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The growing electrification of vehicles and tools increases the demand for low resistance contacts. Today’s batteries for electric vehicles consist of large quantities of single battery cells to reach the desired nominal voltage and energy. Each single cell needs a contacting of its cell terminals, which raises the necessity of an automated contacting process with low joint resistances to reduce the energy loss in the cell transitions. A capable joining process suitable for highly electrically conductive materials like copper or aluminium is the laser beam welding. This study contains the theo

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Chen, Zhe, Dennis J. Eastburn, and Min Han. "The Caenorhabditis elegans Nuclear Receptor Gene nhr-25 Regulates Epidermal Cell Development." Molecular and Cellular Biology 24, no. 17 (2004): 7345–58. http://dx.doi.org/10.1128/mcb.24.17.7345-7358.2004.

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ABSTRACT The development of the epidermis of Caenorhabditis elegans involves cell fusion, migration, and differentiation events. To understand the mechanisms underlying these processes, we characterized the roles of NHR-25, a member of the nuclear receptor family of transcription factors. The NHR-25 homologs Ftz-F1 in Drosophila and SF-1 in mammals are involved in various biological processes, including regulation of patterning during development, reproduction, metabolism, metamorphosis, and homeostasis. Impairment of nhr-25 activity leads to severe phenotypes in embryos and many postembryonic

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Deng, Xian, Gero Fink, Tanmay A. M. Bharat, Shaoda He, Danguole Kureisaite-Ciziene, and Jan Löwe. "Four-stranded mini microtubules formed by Prosthecobacter BtubAB show dynamic instability." Proceedings of the National Academy of Sciences 114, no. 29 (2017): E5950—E5958. http://dx.doi.org/10.1073/pnas.1705062114.

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Microtubules, the dynamic, yet stiff hollow tubes built from αβ-tubulin protein heterodimers, are thought to be present only in eukaryotic cells. Here, we report a 3.6-Å helical reconstruction electron cryomicroscopy structure of four-stranded mini microtubules formed by bacterial tubulin-like Prosthecobacter dejongeii BtubAB proteins. Despite their much smaller diameter, mini microtubules share many key structural features with eukaryotic microtubules, such as an M-loop, alternating subunits, and a seam that breaks overall helical symmetry. Using in vitro total internal reflection fluorescenc

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Bandyopadhyay, Jaya, Jiyeon Lee, Jungsoo Lee, et al. "Calcineurin, a Calcium/Calmodulin-dependent Protein Phosphatase, Is Involved in Movement, Fertility, Egg Laying, and Growth inCaenorhabditis elegans." Molecular Biology of the Cell 13, no. 9 (2002): 3281–93. http://dx.doi.org/10.1091/mbc.e02-01-0005.

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Calcineurin is a Ca2+-calmodulin–dependent serine/threonine protein phosphatase that has been implicated in various signaling pathways. Here we report the identification and characterization of calcineurin genes in Caenorhabditis elegans (cna-1 and cnb-1), which share high homology with Drosophila and mammalian calcineurin genes. C. elegans calcineurin binds calcium and functions as a heterodimeric protein phosphatase establishing its biochemical conservation in the nematode. Calcineurin is expressed in hypodermal seam cells, body-wall muscle, vulva muscle, neuronal cells, and in sperm and the

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van der Horst, Suzanne E. M., Janine Cravo, Alison Woollard, Juliane Teapal та Sander van den Heuvel. "C. elegans Runx/CBFβ suppresses POP-1 TCF to convert asymmetric to proliferative division of stem cell-like seam cells". Development 146, № 22 (2019): dev180034. http://dx.doi.org/10.1242/dev.180034.

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Hollatz, Sören, Marc Hummel, Lea Jaklen, Wiktor Lipnicki, Alexander Olowinsky, and Arnold Gillner. "Processing of Keyhole Depth Measurement Data during Laser Beam Micro Welding." Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications 234, no. 5 (2020): 722–31. http://dx.doi.org/10.1177/1464420720916759.

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Analysing the quality of weld seams is still a challenging task. An optical inspection of the surface is giving limited information about the shape and depth of the weld seam. An application for laser beam welding with high demands regarding the weld depth consistency is the electrical contacting of battery cells. The batteries themselves have a limited terminal or case thickness that must not be penetrated during the welding process to avoid leakage or damage to the cell. That leads to a minimum weld depth to ensure the electrical functionality, and a maximum weld depth indicated by the case

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Bettinger, J. C., S. Euling, and A. E. Rougvie. "The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans." Development 124, no. 21 (1997): 4333–42. http://dx.doi.org/10.1242/dev.124.21.4333.

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Caenorhabditis elegans vulval development culminates during exit from the L4-to-adult molt with the formation of an opening through the adult hypodermis and cuticle that is used for egg laying and mating. Vulva formation requires the heterochronic gene lin-29, which triggers hypodermal cell terminal differentiation during the final molt. lin-29 mutants are unable to lay eggs or mate because no vulval opening forms; instead, a protrusion forms at the site of the vulva. We demonstrate through analysis of genetic mosaics that lin-29 is absolutely required in a small subset of lateral hypodermal s

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Smith, J. A. "The Caenorhabditis elegans GATA factor elt-1 is essential for differentiation and maintenance of hypodermal seam cells and for normal locomotion." Journal of Cell Science 118, no. 24 (2005): 5709–19. http://dx.doi.org/10.1242/jcs.02678.

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Drace, Kevin, Stephanie McLaughlin, and Creg Darby. "Caenorhabditis elegans BAH-1 Is a DUF23 Protein Expressed in Seam Cells and Required for Microbial Biofilm Binding to the Cuticle." PLoS ONE 4, no. 8 (2009): e6741. http://dx.doi.org/10.1371/journal.pone.0006741.

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Dervišević, Irma, Duško Minić, Milan Kolarević, Željko Kamberović, and Mirjana Ristić. "Study on Properties of Alloys with Gallium, Antimony and Zinc from Recycling." Ecological Chemistry and Engineering S 20, no. 3 (2013): 579–99. http://dx.doi.org/10.2478/eces-2013-0042.

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Abstract Alloys with gallium, antimony and zinc, whose elements, metal constituent WEEE (they are specified for mobile phones) are particularly important for developing photoelectron devices, simple reproductive methods of producing p-n structures GaSb, also for production and construction of photo-wave cells in solar panels and they are also processes which develop ceramic semiconductors. In addition, these alloys represent possible substitute for standard lead-tin seam. For the complete definition of the properties of the ternary Ga-Sb-Zn system there were performed many researches of the al

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Gilleard, J. S., and J. D. McGhee. "Activation of Hypodermal Differentiation in theCaenorhabditis elegans Embryo by GATA Transcription Factors ELT-1 and ELT-3." Molecular and Cellular Biology 21, no. 7 (2001): 2533–44. http://dx.doi.org/10.1128/mcb.21.7.2533-2544.2001.

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ABSTRACT The Caenorhabditis elegans GATA transcription factor genes elt-1 and elt-3 are expressed in the embryonic hypodermis (also called the epidermis). elt-1 is expressed in precursor cells and is essential for the production of most hypodermal cells (22). elt-3 is expressed in all of the major hypodermal cells except the lateral seam cells, and expression is initiated immediately after the terminal division of precursor lineages (13). Although this expression pattern suggests a role for ELT-3 in hypodermal development, no functional studies have yet been performed. In the present paper, we

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Hirata, Azumi, Kentaro Katayama, Takehito Tsuji, et al. "Heparanase Localization during Palatogenesis in Mice." BioMed Research International 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/760236.

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Palatogenesis is directed by epithelial-mesenchymal interactions and results partly from remodeling of the extracellular matrix (ECM) of the palatal shelves. Here, we assessed heparanase distribution in developing mouse palates. No heparanase was observed in the vertically oriented palatal shelves in early stages of palate formation. As palate formation progressed, the palatal shelves were reorganized and arranged horizontally above the tongue, and heparanase localized to the epithelial cells of these shelves. When the palatal bilateral shelves first made contact, the heparanase localized to e

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Takigawa, Toshiya, and Kohei Shiota. "Terminal differentiation of palatal medial edge epithelial cells in vitro is not necessarily dependent on palatal shelf contact and midline epithelial seam formation." International Journal of Developmental Biology 48, no. 4 (2004): 307–17. http://dx.doi.org/10.1387/ijdb.041840tt.

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Ginzburg, Val E., Peter J. Roy, and Joseph G. Culotti. "Semaphorin 1a and semaphorin 1b are required for correct epidermal cell positioning and adhesion during morphogenesis in C. elegans." Development 129, no. 9 (2002): 2065–78. http://dx.doi.org/10.1242/dev.129.9.2065.

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The semaphorin family comprises secreted and transmembrane proteins involved in axon guidance and cell migration. We have isolated and characterized deletion mutants of C. elegans semaphorin 1a (Ce-sema-1a or smp-1) and semaphorin 1b (Ce-sema-1b or smp-2) genes. Both mutants exhibit defects in epidermal functions. For example, the R1.a-derived ray precursor cells frequently fail to change anterior/posterior positions completely relative to their sister tail lateral epidermal precursor cell R1.p, causing ray 1 to be formed anterior to its normal position next to ray 2. The ray cells, which norm

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Taya, Y., S. O'Kane, and M. W. Ferguson. "Pathogenesis of cleft palate in TGF-beta3 knockout mice." Development 126, no. 17 (1999): 3869–79. http://dx.doi.org/10.1242/dev.126.17.3869.

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We previously reported that mutation of the transforming growth factor-beta3 (TGF-beta3) gene caused cleft palate in homozygous null (−/−) mice. TGF-beta3 is normally expressed in the medial edge epithelial (MEE) cells of the palatal shelf. In the present study, we investigated the mechanisms by which TGF-beta3 deletions caused cleft palate in 129 × CF-1 mice. For organ culture, palatal shelves were dissected from embryonic day 13.5 (E13.5) mouse embryos. Palatal shelves were placed singly or in pairs on Millipore filters and cultured in DMEM/F12 medium. Shelves were placed in homologous (+/+

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Rougvie, A. E., and V. Ambros. "The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans." Development 121, no. 8 (1995): 2491–500. http://dx.doi.org/10.1242/dev.121.8.2491.

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A hierarchy of heterochronic genes, lin-4, lin-14, lin-28 and lin-29, temporally restricts terminal differentiation of Caenorhabditis elegans hypodermal seam cells to the final molt. This terminal differentiation event involves cell cycle exit, cell fusion and the differential regulation of genes expressed in the larval versus adult hypodermis. lin-29 is the most downstream gene in the developmental timing pathway and thus it is the most direct known regulator of these diverse processes. We show that lin-29 encodes a protein with five zinc fingers of the (Cys)2-(His)2 class and thus likely con

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Ferrer-Roca, Olga, José A. Pérez Gómez, and Maritza Estévez. "Chromatin Texture from Hematoxylin Stained Thyroid Lesions." Analytical Cellular Pathology 17, no. 4 (1998): 209–17. http://dx.doi.org/10.1155/1998/320465.

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Quantitative aspects of cytology and histology should be considered in diagnostic standardisation processes. The present paper summarises the cytological differences detected in 75 thyroid lesions using a computerized textural analysis.Cells stained with progressive hematoxylin and taken from paraffin blocks were overlaid with the extracted texture. This technique was based on the lineal detection of a grey level gradient of the common logarithm of the integrated optical density (IOD) of each nucleus.Diffuse and nodular goiters (36 cases) were demonstrated to be composed of small cells contain

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Hughes, S., C. Brabin, P. J. Appleford, and A. Woollard. "CEH-20/Pbx and UNC-62/Meis function upstream of rnt-1/Runx to regulate asymmetric divisions of the C. elegans stem-like seam cells." Biology Open 2, no. 7 (2013): 718–27. http://dx.doi.org/10.1242/bio.20134549.

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Gorrepati, L., K. W. Thompson, and D. M. Eisenmann. "C. elegans GATA factors EGL-18 and ELT-6 function downstream of Wnt signaling to maintain the progenitor fate during larval asymmetric divisions of the seam cells." Development 140, no. 10 (2013): 2093–102. http://dx.doi.org/10.1242/dev.091124.

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