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1

B, Krajnc, Mavko Borut, and U.S. Nuclear Regulatory Commission, eds. Analyzing operator actions during loss of ac power accident with subsequent loss of secondary heat sink. U.S. Nuclear Regulatory Commission, 2010.

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2

L, Perneczky, U.S. Nuclear Regulatory Commission. Office of Nuclear Regulatory Research, and KFKI Atomenergia Kutatóintézet (Magyar Tudományos Akadémia), eds. Description and RELAP5 assessment of the PMK-2 CAMP-CLB experiment: 2% cold leg break without HPIS with secondary bleed. Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, 2001.

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3

Yamamoto, Atsumasa. Decay of secondary flow and the associated loss variation downstream of an annular turbine stator cascade. National Aerospace Laboratory, 1989.

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4

Harvey, Marilyn. A resource bank on loss & grief: "It hurts...". Youth Clubs UK, 1999.

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5

Nuffield Institute for Health Services Studies., University of York. Centre for Health Economics., NHS Centre for Reviews & Dissemination., and Royal College of Physicians of London. Research Unit., eds. The Management of menorrhagia: What are effective ways of treating excessive regular menstrual blood loss in primary and secondary care?. Nuffield Institute for Health, University of Leeds, 1995.

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6

Garrido, David. Profit or loss: A study of the emergence of non profit making companies in the world of maintained secondary education : (MA Education dissertation). [University of Surrey], 1996.

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7

Cortes, Yamnia Ivelisse. Role of Menopause-Related Factors and Depression in Cardiovascular Disease Risk and Bone Loss in Postmenopausal Minority Women with HIV: A Secondary Analysis. [publisher not identified], 2015.

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8

Barbara, Ward. Good grief [1]: Talking and learning about loss and death. Good Grief Associates, 1988.

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9

Dawson, Steve. Adventure in the land of grief: A 9-week curriculum for children's bereavement groups : introducing Griefdramatics. Words on the Wind Pub., 1997.

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10

Barbara, Ward. Good grief [2]: Exploring feelings, loss, and death with under 11's : a holistic approach. Good Grief, 1989.

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11

Rowling, Louise. Grief in school communities: Effective support strategies. Open University, 2003.

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12

Chbosky, Stephen. The Perks of Being a Wallflower. 7th ed. Pocket Books, 2009.

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13

Chbosky, Stephen. The Perks of Being a Wallflower. Pocket Books, 1999.

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14

Chbosky, Stephen. Las ventajas de ser invisible. Gallery Books/MTV Books, 2013.

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15

Chbosky, Stephen. The Perks of Being a Wallflower. Pocket Books, 2009.

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16

Chbosky, Stephen. Las ventajas de ser invisible. Alfaguara, 2014.

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17

Chbosky, Stephen. The Perks of Being a Wallflower. Simon & Schuster, 2012.

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18

Chbosky, Stephen. Le monde de Charlie. Editions SARBACANE, 2012.

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19

Chbosky, Stephen. The Perks of Being a Wallflower. 6th ed. MTV Books, 2012.

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20

Chbosky, Stephen. The perks of being a wallflower. Pocket Books, 1999.

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21

Long, Rob. Loss and Separation. Fulton Publishers, David, 2014.

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22

Long, Rob. Loss and Separation. Fulton Publishers, David, 2014.

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23

Long, Rob. Loss and Separation. Fulton Publishers, David, 2014.

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24

Long, Rob. Loss and Separation. Fulton Publishers, David, 2014.

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25

Hunt, Jan. LOSS, GRIEF AND HEALING - A PROCESS, For Elementary and Secondary School Students. Cambridge Cottage Press, 1999.

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26

Bickmore, Steven T., and Michelle M. Falter. When Loss Gets Personal: Discussing Death Through Literature in the Secondary ELA Classroom. Rowman & Littlefield Publishers, Incorporated, 2018.

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27

Davies, Emily. Blistering rashes. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0069.

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A blister is a fluid-filled, circumscribed elevation of the skin. By convention, blisters are divided by size; blisters less than 0.5 cm wide are called vesicles, and those greater than 0.5 cm wide are called bullae. A blistering rash is used to describe any skin condition which morphologically consists of vesicles or bullae. Vesicles more than 48 hours old may evolve into pustules (pus-filled lesions). Pustular eruptions have not been included in this chapter. Secondary lesions include erosions (partial loss of epidermis), which may occur when a superficial blister ruptures or is scratched, a
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28

Costello, Kathleen, and Scott D. Newsome. Symptoms of Multiple Sclerosis. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0085.

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Symptoms of MS can be categorized as primary, secondary, or tertiary. Primary symptoms are those that are a direct result of CNS damage, such as fatigue, bladder dysfunction, visual disturbances, incoordination or imbalance, etc. Secondary symptoms are complications arising from these symptoms such as falls due to imbalance, spasticity or weakness, or UTI due to bladder retention. Tertiary symptoms are the social and vocational consequences of primary and secondary symptoms and can include divorce, job loss, financial hardship, and social isolation. Careful evaluation of these symptoms along w
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29

Ahuja, Christopher S., and Michael Fehlings. Neuroprotection for Spinal Cord Injury. Edited by David L. Reich, Stephan Mayer, and Suzan Uysal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190280253.003.0015.

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Traumatic spinal cord injuries (SCI) often have a devastating impact on quality of life for patients and their families. Neuroprotection for spinal cord injury is aimed at improving functional outcomes by limiting secondary injury processes that occur within the first minutes, hours, and days following the primary injury. The primary mechanical trauma initiates a secondary injury cascade where ischemia, inflammatory cell infiltration, and cytotoxic changes in the microenvironment cause further cell death and loss of function. Time-sensitive neuroprotective measures targeting these secondary in
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30

Loss and Separation (Building Success Through Better Behaviour). David Fulton Publish, 2005.

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31

Bickmore, Steven T., and Michelle M. Falter. Moving Beyond Personal Loss to Societal Grieving: Discussing Death's Social Impact Through Literature in the Secondary ELA Classroom. Rowman & Littlefield Publishers, Incorporated, 2018.

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32

Falter, Michelle M., and Steven T. Bickmore Associate Professor of English Education University of Nevada Las Vegas; curator Dr. Bickmore’s YA Wednesday Blog. Moving Beyond Personal Loss to Societal Grieving: Discussing Death's Social Impact through Literature in the Secondary ELA Classroom. Rowman & Littlefield Publishers, 2018.

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33

McDougall, Robert. Management of Burn Patients for Grafting and Excision. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0026.

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Anesthesia management for excision and grafting of burns in a child can be extremely challenging. Early excision of burned tissue significantly decreases morbidity and mortality but often involves procedures that lead to significant blood loss. Burn patients also have a markedly increased metabolic rate secondary to the inflammatory response to the burn. Burn patients may be difficult to monitor, are at risk of hypothermia, and present complex pain-management problems.
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34

Abcejo, Arnoley S., and Jeffrey J. Pasternak. Neurogenic Shock. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0072.

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Neurogenic shock is a pathophysiologic state of systemic hypoperfusion characterized by a significant decrease in systemic vascular resistance secondary to loss of sympathetic tone. Neurogenic shock is most commonly seen in the setting of acute spinal cord injury (SCI) but can also occur following significant brain injury. Interruption of sympathetic fibers causes loss of basal vascular sympathetic tone, commonly allowing unopposed parasympathetic tone. As a result, severe hypotension and bradycardia can further exacerbate neurologic injury and organ perfusion. Understanding the physiologic an
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35

Johnson, Ron, and Deb Brock. The Positive Power of Sadness. Praeger, 2017. http://dx.doi.org/10.5040/9798400699368.

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Written by two clinical psychologists with nearly a century of combined experience, this book explains how people who suffer from depression, anxiety, or undue anger can overcome these difficulties by allowing the normal process of grieving to occur. Sadness is generally characterized as a negative emotion, yet experiencing sadness plays a positive and key role in achieving and maintaining mental health and in avoiding anxiety, depression, and anger. Indeed, sadness can be understood as a normal and necessary feeling that always occurs when one loses something that is loved. The Positive Power
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36

Garrido, David. Profit or loss: A study of the emergence of non profit making companies in the world of maintained secondary education. 1996.

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37

Fink, John K. Upper Motor Neuron Disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0031.

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Symptomatic disturbance of corticospinal and corticobulbar tracts (collectively, the upper motor neuron UMN) occurs in innumerable acquired central nervous system disorders including the consequences of trauma, hypoxia-ischemia, inflammation (e.g. multiple sclerosis), toxins (e.g. thiocyanate1 and specific organophosphorus compound toxicity2) and deficiencies (e.g. hypocupremia3 and vitamin B12 deficiency). Variable degrees of UMN disturbance frequently accompany degenerative disorders in which disturbance of another neurologic system results in the primary clinical. Neuropathologic studies ha
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38

Frenkel, Catherine, and Aurora Pryor. Revisional Bariatric Surgery. Edited by Tomasz Rogula, Philip Schauer, and Tammy Fouse. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190608347.003.0024.

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The annual volume of bariatric surgery is growing, giving rise to an increase in complications requiring complex management, including revision. Bariatric revision procedures are also becoming increasingly necessary for weight-loss recidivism and patients at the extreme of obesity. This chapter outlines clinical management pathways used to address secondary bariatric surgery. It summarizes reasons for, and outcomes with, revision of a laparoscopic gastric band, vertical banded gastroplasty, sleeve gastrectomy, or Roux-en-Y gastric bypass. Surgical techniques used to manage weight regain or fai
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39

Aisiku, Imoigele, and Claudia S. Robertson. Epidemiology and pathophysiology of traumatic brain injury. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0341.

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Although medical management of traumatic brain injury (TBI) may have improved in developed countries, TBI is still a major cause of mortality and morbidity. The demographics are skewed towards the younger patient population, and affects males more than females, but in general follow a bimodal distribution with peaks affecting young adults and the elderly. As a result, the loss of functional years is devastating. Pathology due to brain trauma is a complex two-hit phenomenon, frequently divided into ‘primary’ and ‘secondary’ injury. Hypoxia, ischaemia, and inflammation all play a role, and the i
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40

Caga, Jashelle, and Matthew C. Kiernan. Bulbar dysfunction in ALS: Psychological implications. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757726.003.0015.

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Bulbar dysfunction typically manifests as speech and swallowing impairment in amyotrophic lateral sclerosis (ALS). Timely assessment of changes in speech and swallowing is imperative, given its negative prognostic implication and impact on psychological well-being. The progressive loss of the ability to speak and swallow can also result in threats to the self-concept, which may compound issues with social interaction. The use of communication devices to accommodate loss of speech appears to be beneficial in reducing patient distress and caregiver burden. Implementation of interventions to mana
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41

Roos, Raymund A. C. Clinical Neurology. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199929146.003.0002.

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Huntington’s disease (HD) is an autosomal dominant inherited disorder characterized by motor behavior changes, chorea and hypokinesia, psychiatric disturbances, and dementia. In this chapter the clinical symptoms and signs of the changes in motor behavior are described in detail as they evolve from the premanifest stage, through the conversion to manifest disease, and finally the to the last stage of the disease. Attention is also given to the less well known secondary signs of HD, such as weight loss, sleep disturbances, and autonomic dysregulation. The first presentation of the illness and t
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42

Merten, Thomas. False Symptom Claims and Symptom Validity Assessment. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190612016.003.0012.

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False symptom claims and distorted symptom presentations are not at all rare in civil and criminal forensic cases where secondary gain is immanent. They reach from reported nonspecific memory and attention problems to intellectual disability, full-blown autobiographical memory loss, or crime-related amnesia. Symptom validity assessment has, to a large extent, been developed by clinical neuropsychologists to distinguish between authentic and nonauthentic symptom presentations. Malingering is only one of several manifestations of uncooperativeness. Today, most forensic neuropsychology experts wo
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43

Youngblood, Mark W., and Hal Blumenfeld. Biological Basis of Primary Generalized Epilepsies—Pathophysiology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0037.

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The primary generalized epilepsies include a heterogeneous group of seizures including absence, myoclonic, and generalized tonic-clonic seizures that are not strictly localized on EEG and not secondary to another disorder. The seizures are often associated with a loss of consciousness and may present with motor manifestations, including convulsions and arrest of respiration. Generalized spike-and-wave discharges on electroencephalogram are a uniting feature, and this pattern of activity is a direct manifestation of the underlying mechanism of these disorders. A review of important underlying c
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44

Brallier, Jess W., and Jonathan S. Gal. Neuroprotection for Spine Surgery. Edited by David L. Reich, Stephan Mayer, and Suzan Uysal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190280253.003.0020.

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Perioperative neurologic injury related to spine surgery, albeit rare, can result in devastating functional loss. As the number of spine operations has increased, so has the need for strategies designed to avoid and protect against such injury. This chapter reviews the common etiologies of neurologic deficits secondary to spine surgery and the factors that place patients at increased risk for developing these complications. The use of intraoperative neuromonitoring, including somatosensory evoked potentials (SSEPs), electromyography (EMG), and transcranial motor evoked potentials (TcMEPs), to
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45

Jolly, Elaine, Andrew Fry, and Afzal Chaudhry, eds. Neurology and neurosurgery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199230457.003.0014.

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Chapter 14 covers the basic science and clinical topics relating to neurology and neurosurgery which trainees are required to learn as part of their basic training and demonstrate in the MRCP. It covers the approach to the neurological Patient, neurological examination, neurological investigations, coma, acquired brain injury, encephalopathies, alcohol and the nervous system, brainstem disorders, common cranial nerve disorders, migraine, other primary headaches, secondary headache, neuro-ophthalmology, vertigo and hearing loss, seizures and epilepsy, intracranial pressure, stroke, central nerv
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46

Chakera, Aron, William G. Herrington, and Christopher A. O’Callaghan. Oliguria and anuria. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0056.

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Oliguria can be caused by any factor that affects renal function, or the free passage of urine down the urinary tract. Complete anuria most commonly occurs in men as a consequence of bladder outlet obstruction from an enlarged prostate. It can also arise in patients who have a single functioning kidney which then becomes obstructed or loses its vascular supply. Oliguria occurs commonly in hospitalized patients, is usually secondary to impaired renal perfusion, and is often predictable. The elderly and more unwell patients, for example, those in critical care settings, are most at risk. The pre
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47

Beattie, R. Mark, Anil Dhawan, and John W.L. Puntis. Eating disorders. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0015.

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Anorexia nervosa 110Bulimia nervosa 112Eating disorders are defined as persistent disturbance of eating (± behaviour) that impairs physical health or psychosocial functioning or both and that is not secondary to any other medical or psychiatric disorder.Anorexia nervosa is a complex disorder described in a number of different ways and recognized for >100 years. It involves voluntary self-starvation, with weight loss, or avoidance of weight gain during adolescence. Peak age of onset is in mid-teens, with a female to male ratio of 10:1, and a prevalence of around 1%. Genetic factors are impor
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48

Yaqoob, Muhammad M., Katherine Bennett-Richards, and Islam Junaid. Retroperitoneal fibrosis. Edited by Adrian Woolf. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0357.

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Retroperitoneal fibrosis (RPF) is a rare but multifaceted disease which encompasses a range of conditions characterized by the presence of a fibro-inflammatory tissue, which usually surrounds the abdominal aorta, iliac arteries, and extends into the retroperitoneum to entrap ureters with resultant unilateral or bilateral obstruction, usually at the junction between the middle and lower thirds of the ureter. The condition is progressive: initially, the fibrous tissue is fairly cellular, later becoming relatively acellular. The mechanism by which obstruction occurs is probably due to loss of per
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49

Donaghy, Michael. Focal peripheral neuropathy. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569381.003.0487.

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Some causes of focal peripheral nerve damage are self-evident, such as involvement at sites of trauma, tissue necrosis, infiltration by tumour, or damage by radiotherapy. Focal compressive and entrapment neuropathies are particularly valuable to identify in civilian practice, since recovery may follow relief of the compression. Leprosy is a common global cause of focal neuropathy, which involves prominent loss of pain sensation with secondary acromutilation, and requires early antibiotic treatment. Mononeuritis multiplex due to vasculitis requires prompt diagnosis and immunosuppressive treatme
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50

Grundy, Seamus. Pleural effusion. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0019.

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Pleural effusion is a common clinical problem which can present both to primary and secondary care. The process by which fluid accumulates can be divided into transudative or exudative. Transudative effusions occur in the presence of normal pleura and are caused by increased oncotic or hydrostatic pressures. Exudative effusions are associated with abnormal pleura and are caused either by increased pleural fluid production due to local inflammation or infiltration or by decreased fluid removal which is caused by obstruction of the lymphatic drainage system. Patients may be entirely asymptomatic
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