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Journal articles on the topic 'Secondary Ocular Tuberculosis'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Wang, Shuang, Yajie Gong, Keke Huang, and Jun Huang. "Peripheral ulcerative keratitis secondary to tuberculosis: A case report and literature review." Medicine 103, no. 35 (2024): e39482. http://dx.doi.org/10.1097/md.0000000000039482.

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Rationale: Compared with intraocular tuberculosis, ocular tuberculosis with ocular surface involvement is rare. Corneal involvement in ocular tuberculosis may include interstitial keratitis or peripheral ulcerative keratitis. We report a case of peripheral ulcerative keratitis directly caused by tuberculosis. Patient concerns: A 20-year-old man complained of vision loss and pain in the left eye that had lasted for 1 week. A slit lamp examination of the left eye showed a corneal epithelial defect, interstitial corneal edema, and a white irregular infiltrative lesion and ulcer (with the dimensio

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2

Taneja, Anuj. "Chronic Ulcerative Eyelid Lesion: A Rare Manifestation of Tuberculosis." Indian Journal of Emergency Medicine 4, no. 1 (2018): 46–48. http://dx.doi.org/10.21088/ijem.2395.311x.4118.8.

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Any organ system in the body can be affected by tuberculosis. While pulmonary tuberculosis is the most common presentation, extrapulmonary tuberculosis including ocular tuberculosis is also an important clinical problem. Most commonly, ocular tuberculosis presents as anterior uveitis or choroiditis which is caused either by hematogenous infection or hypersensitivity after another organ infection. Eyelid involvement by tuberculosis is mostly secondary to orbital tuberculosis and often presents as a draining sinus. Isolated eyelid tuberculosis is however uncommon. We present the case of a 6 year

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3

Verma, Shweta, and Kudrat Jyoti. "Giant Choroidal Tuberculoma as a Presenting Feature of Tuberculosis." Delhi Journal of Ophthalmology 33, no. 2 (2023): 107–9. https://doi.org/10.4103/dljo.dljo_67_23.

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Tuberculosis (TB) is a very common systemic disease in India. As per the Global TB Report 2021, the estimated incidence of all forms of TB in India for 2020 was 188/100,000 population. Ocular TB may not be associated with clinical evidence of pulmonary TB; up to 60% of patients with evidence of extrapulmonary TB may not have been diagnosed pulmonary TB. Choroidal tuberculomas have been reported in the literature as a manifestation of ocular TB secondary to pulmonary TB. Here, we present a case of giant choroidal tuberculoma who presented to our OPD without any prior history of pulmonary TB.

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Ganasan, Diymitra K., Nurul Ain Shahrudin, Aida Zairani Mohd Zahidin, Safinaz Mohd Khialdin, and Norshamsiah Md Din. "Bilateral optic neuritis secondary to presumed ocular tuberculosis in immunocompetent adults." Malaysian Journal of Ophthalmology 1, no. 1 (2019): 66–72. http://dx.doi.org/10.35119/myjo.v1i1.5.

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This case series aims to discuss cases of bilateral optic neuritis secondary to presumed ocular tuberculosis (TB) in two immunocompetent adults. Ocular TB has been associated with optic neuritis, but bilateral cases in immunocompetent individuals are rarely seen. We report a case series of two young healthy adults with bilateral painless optic neuritis as the presenting feature of ocular TB. Clinical examination, TB tests, and angiographic studies supported the diagnosis. All patients were started on anti-TB medication followed by oral prednisolone and had visual improvement a few weeks after

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Dr, K. Priyanka, Y. M. S. Prasad Dr, P. R. Siva Sankar Dr, and Hari Hara Prasad Dr. "A Case Series of Ocular Manifestations in Tuberculosis." A Case Series of Ocular Manifestations in Tuberculosis 9, no. 1 (2024): 4. https://doi.org/10.5281/zenodo.10628906.

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To evaluate and understand the clinical manifestation and prevalence of ocular morbidity in Pulmonary tuberculosis patients. Lungs are primarily affected by Tuberculosis. Secondary involvement may occur in any organ including eye. Any part of the eye could potentially be affected by TB and its clinical manifestations can vary. Materials & Methods : A hospital based observational study was conducted in government general hospital, Ananthapuramu for a period of 6 months from December 2022 to May 2023.Patients who were diagnosed as systemic tuberculosis on ATT were evaluated for ophthalmic in

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6

Sachdeva, Amit, and Rahul Rao. "Through the Patient's Eyes: Unmasking Ocular Tuberculosis and the Urgent Need for Specialized Care." Journal of Pioneering Medical Sciences 14, no. 1 (2025): 73–77. https://doi.org/10.47310/jpms2025140110.

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This case report describes the diagnostic odyssey of a 41-year-old woman with recurrent uveitis, ultimately diagnosed with presumed ocular tuberculosis. Initial consultations at a secondary care facility failed to identify the underlying cause, leading to delays in appropriate treatment and the development of complications, including cataracts and posterior synechiae. Referral to a specialized eye institute resulted in a positive interferon-gamma release assay (IGRA) and initiation of anti-tubercular therapy. This case highlights the challenges in diagnosing and managing uveitis, the importanc

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7

Vinutha, B. V., Rashmi Shetu, Sundeep, Konduru Rishitha, V. Pallavi Naragund, and J. Babitha. "Clinical Profile of Anterior Uveitis in Tertiary Eye Care Center." Journal of Medical Sciences and Health 9, no. 2 (2023): 224–28. http://dx.doi.org/10.46347/jmsh.v9i2.23.2.

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Purpose: To describe the clinical features, causes and management of patients with acute anterior uveitis. Methods: A prospective study of clinical features, complication and prognosis was done on anterior uveitis patients for a period of 10 months. Detailed history, complete ocular examination, systemic evaluation and relevant investigations were done in 64 patients, appropriate systemic and ocular management was done. Results: Of 64 patients, 65.6% were male and 34.3% female. Mean age of presentation was 42.6 years. 71.8% unilateral and 28.1% bilateral eye involvement was seen. Visual acuity

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8

Ducci, Filippo, Francesca Mariotti, Jessica Mencarini, et al. "Hemophagocytic Lymphohistiocytosis and Miliary Tuberculosis in an Apparently Immunocompetent Patient: A Case Report." Infectious Disease Reports 16, no. 4 (2024): 763–69. http://dx.doi.org/10.3390/idr16040058.

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Hemophagocytic lymphohistiocytosis (HLH) is a serious haematologic condition that can be related to various diseases, including tuberculosis (TB). The patient is a previously healthy 26-year-old man, originally from western Africa, admitted to hospital for fever and weight loss. Given the results of a computed tomography (CT) scan, ocular examination and microbiologic tests, miliary TB with pulmonary, lymph nodal and ocular involvement was diagnosed. Following the introduction of antitubercular treatment (ATT), an increase in inflammation indexes and severe pancytopenia were observed; at this

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9

Kabra, Meenakshi, Sarita Beri, Rajiv Garg, et al. "An Unusual Case of Metastatic Tubercular Endophthalmitis." Delhi Journal of Ophthalmology 21, no. 1 (2010): 48–49. https://doi.org/10.4103/0972-0200.377289.

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Tuberculosis is prevalent in developing countries like India, however ocular tuberculosis is a diagnosis of exclusion. This unusual case is of an 18 year old patient of pulmonary Kochs who presented to the out patient department of our hospital with unilateral acute pain in right eye with the marked diminuition of vision of 3 days duration. On Examination his vision in Right eye was PL-negative. This was preceded by gradual painful loss of vision in the right eye for the past two months duration for which he was already taking medication. He was diagnosed as a case of endophthalmitis with seco

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10

V, Vinutha, Kiran Kumar, Smitha S, Rashmi S, Sundeep Shetty, and Konduru Rishitha. "Clinical profile of anterior uveitis in a tertiary eye care center." National Journal of Physiology, Pharmacy and Pharmacology 13, no. 7 (2023): 1. http://dx.doi.org/10.5455/njppp.2023.13.06298202308062023.

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Background: Anterior uveitis is the inflammation of the anterior uveal tissue that is iris and pars plicata of the ciliary body. Due to varied etiology, detailed history and systematic investigations are needed for accurate diagnosis and management. Aims and Objectives: The aims of this study were to describe the clinical features, causes, and management of patients with acute anterior uveitis. Materials and Methods: A prospective study of clinical features, complication, and prognosis was done on anterior uveitis patients for a period of 10 months. Detailed history, complete ocular examinatio

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11

Toomey, Christopher B., Jeffrey Lee, and Doran B. Spencer. "Rifabutin-Cobicistat Drug Interaction Resulting in Severe Bilateral Panuveitis." Case Reports in Ophthalmology 11, no. 1 (2020): 156–60. http://dx.doi.org/10.1159/000506181.

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We report a novel case of severe bilateral panuveitis with hypopyon secondary to rifabutin and cobicistat drug interaction in the setting of human immunodeficiency virus (HIV) infection and latent tuberculosis (TB). A 63-year-old woman presented with bilateral conjunctival injection and decreasing vision of 5 days’ duration. She had a history of well-controlled HIV infection, latent TB, and non-alcoholic steatohepatitis for which she was inadvertently being treated, due to a pharmacy error, concurrently with the anti-TB medicine rifabutin and the highly active antiretroviral therapy combinatio

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12

Pirani, Pelliccioni, De Turris, et al. "The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging." Journal of Clinical Medicine 8, no. 9 (2019): 1392. http://dx.doi.org/10.3390/jcm8091392.

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Background: Syphilis, tuberculosis and toxoplasmosis are major infectious diseases worldwide; all of them are multisystem pathologies and share a possible ocular involvement. In this context, a fundamental help for the definitive diagnosis is provided by the ophthalmologist, through clinical evaluation and with the aid of a multimodal imaging examination. Methods: We hereby describe selected cases who came to our attention and were visited in our eye clinic. In all clinics, the use of retinal and optic disc multimodal imaging during ophthalmological evaluation allowed to make a diagnosis of an

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13

Suryati Mohd, Khamsah, Nor Elani Mat Nafi, Ammira Shafiqha Abdul Khadar, Ainur Awanis Mohd Badiazaman, and Aulia Rani Annisava. "Propolis: Traditional uses, Phytochemical Composition and Pharmacological Properties." International Journal of Engineering & Technology 7, no. 4.43 (2018): 78–82. http://dx.doi.org/10.14419/ijet.v7i4.43.25823.

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Propolis is a sticky material manufactured by bees to build and protect their hive. Propolis had been used worldwide for years in folk medicine. The aim of this paper is to give information about traditional uses, phytochemical screening and pharmacological studies of propolis in the world by using secondary references such as journals and articles. The traditional uses of propolis include home remedies, toothpastes, mouthwashes, creams, drops, dietary supplement, anti-putrefactive, anti-pyretic agent, antiseptic, wound healing agent, tuberculosis treatment, cold syndrome, treatment of burns,

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14

Tasnim, Saria, Dhara Dave, Yousuf Tawfeeq, Tarek Naguib, and Waqas Rasheed. "A case of ocular neurosyphilis in a patient with HIV." Southwest Respiratory and Critical Care Chronicles 9, no. 41 (2021): 44–46. http://dx.doi.org/10.12746/swrccc.v9i41.931.

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In the modern era, neurosyphilis in immunocompetent individuals is very rare compared to pre-antibiotic era. However, the incidence is still a few folds higher in immunodeficient individuals, especially in patients with human immunodeficiency virus (HIV) infection. The cases we found, involved mostly the brain with eye involvement was found in only five other instances. Ocular syphilis is a type of neurosyphilis that can threaten vision leading to blindness if not treated promptly. Its diagnosis can be challenging but it should be considered if the neuro-ophthalmological findings cannot be exp

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15

Sanjay, Srinivasan, Naresh Kumar Yadav, Ankush Kawali, Aditi Gupta, and Padmamalini Mahendradas. "Unilateral macular branch retinal vein occlusion in a healthy Indian woman following coronavirus disease vaccination: a case report and comprehensive literature review." Medical hypothesis, discovery & innovation in optometry 4, no. 2 (2023): 95–101. http://dx.doi.org/10.51329/mehdioptometry178.

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Background: The coronavirus disease (COVID-19) vaccines exert ocular adverse effects, including episcleritis, scleritis, anterior and recurrent uveitis, acute macular neuroretinopathy, paracentral acute middle maculopathy, ophthalmic vein thrombosis, Graves’ disease, arteritic anterior ischemic optic neuropathy, non-arteritic anterior ischemic optic neuropathy, central serous chorioretinopathy, Vogt-Koyanagi-Harada disease, multifocal choroiditis, cranial nerve palsies such as facial or abducens nerve palsy, acute zonal occult outer retinopathy, acute zoster ophthalmicus following re-activatio

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16

Yamamoto, Koichiro, Manami Fujita, Hiroyuki Honda, et al. "Characteristics of Serum Ratios of 1,25-Dihydroxyvitamin D to 25-Hydroxyvitamin D for Assessment of Bone Metabolism." Journal of the Endocrine Society 5, Supplement_1 (2021): A272—A273. http://dx.doi.org/10.1210/jendso/bvab048.553.

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Abstract Vitamin D is obtained in the body by food intake or by production from 7-dehydrocholesterol by exposure of the skin to ultraviolet B radiation. It is first metabolized in the liver to 25-hydroxyvitamin D (25D), which is a major circulating metabolite. In the kidney, 25D is subsequently metabolized to the hormonally active form, 1,25-dihydroxyvitamin D (1,25D), via 1α-hydroxylase encoded by the CYP27B1 gene. 1,25D has a cellular effect through the vitamin D receptor, which leads to calcium absorption in the gut, bone metabolism, and parathyroid function. A recent study showed that a lo

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17

McColl, Jeanine, Teresa Liang, and Dax Rumsey. "Neurological Behcet’s Disease in an Adolescent: A Case Report." Journal of Rheumatology 52, Suppl 2 (2025): 71–72. https://doi.org/10.3899/jrheum.2025-0314.57.

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BackgroundBehcet’s disease (BD) is an idiopathic multisystemic inflammatory disease. There are 2 primary sets of diagnostic criteria. The 1990 International Study Group criteria consists of recurrent oral ulcers at least 3 times in 12 months and 2 or more of the following other features: recurrent genital ulcers, eye lesions (uveitis, retinal vasculitis), skin lesions (erythema nodosum, pseudo folliculitis, papulopustular lesions, or acneiform nodules) or a positive pathergy test (skin papule 2 mm or more 24-48 hrs post-needle insertion).[1,2] The 2014 International Criteria for Behcet Disease

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18

Tanushree, V., and Gowda HT Venkate. "Clinical Study of Primary Ocular Tuberculosis." July 8, 2016. https://doi.org/10.19070/2332-290X-SI08001.

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Introduction: “Primary Ocular Tuberculosis” describes an infection by the M. tuberculosis species that can affect any part of the eye (intraocular/extraocular) without any systemic manifestations. Materials and Methods: Prospective Study was conducted in a tertiary care hospital on patients diagnosed to have primary ocular tuberculosis attending the outpatient and inpatient department of ophthalmology. Results: In our study we reported 7 cases of primary ocular tuberculosis. Tuberculosis of eyelid (1 case), Tuberculosis of conjunctiva (2 cases), Tuberculosis of lacrimal sac (2 cases), Tubercul

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19

Echevarría-Lucas, Lucía, M. Mar Góngora-Miñarro, Cristina Gómez-Cabrera, Margarita Jódar-Márquez, and Juan J. Gómez-Fernández. "Choroiditis due to hypersensitivity secondary to inactive ocular tuberculosis. Case report." Revista Mexicana de Oftalmología (English Edition) 95, no. 5 (2021). http://dx.doi.org/10.24875/rmoe.m21000183.

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20

Dilahara, Tilakaratne, and Kumarasinghe Malith. "Diagnosis, Treatment, and Outcomes of Presumed Ocular Tuberculosis Patients Attending Central Chest Clinic, Colombo." Ophthalmology Research: An International Journal, January 31, 2022, 27–32. http://dx.doi.org/10.9734/or/2022/v16i130225.

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Aims: Main objective of this study was to describe the diagnosis, treatment, outcomes, and associated factors of presumed ocular tuberculosis patients attending Central Chest Clinic, Colombo.  Study Design, Place and Duration: A cross sectional descriptive study was conducted among all ocular tuberculosis patients referred to Central Chest Clinic, Colombo for treatment from 1st of January 2016 to 31st June 2018. Methodology: Pretested content validated secondary data extraction form was used. Socio-demographic and work-related characteristics were analysed using frequency distribut

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21

Dreyer, Justin, Lauren Kiryakoza, Jonathan Tijerina, Thomas Albini, and Guillermo Amescua. "Rare bilateral corneoscleral perforation secondary to ocular tuberculosis: a case report and clinical insights." Journal of Ophthalmic Inflammation and Infection 15, no. 1 (2025). https://doi.org/10.1186/s12348-025-00472-y.

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Abstract Background This case represents a rare presentation of bilateral corneoscleral perforation secondary to presumed ocular mycobacterium tuberculosis infection with the goal of reporting a case of bilateral corneoscleral perforation in the setting of a positive interferon-γ release assay (IGRA) test. Findings A 27-year-old patient presented with five months of redness, worsening eye pain, and five days of decreasing vision. Visual acuity (VA) was counting fingers bilaterally. Intraocular pressure (IOP) was 10 mmHg and 19 mmHg in the right and left eye, respectively. A slit lamp examinati

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22

Murphy, Melissa L., and Duncan Rogers. "Tuberculosis reactivation demonstrated by choroiditis and inflammatory choroidal neovascular membrane in a patient treated with immune checkpoint inhibitors for malignant mucosal melanoma." Journal of Ophthalmic Inflammation and Infection 13, no. 1 (2023). http://dx.doi.org/10.1186/s12348-023-00374-x.

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Abstract Purpose To describe a complex case of ocular tuberculosis reactivation with anterior uveitis, choroiditis and inflammatory choroidal neovascular membrane (CNVM) following immune checkpoint inhibitor (ICPI) treatment of malignant mucosal melanoma. Methods A retrospective collection of medical history, clinical findings and multimodal imaging with literature review of the topic was conducted. Results A 52-year-old Romanian female developed reduced vision and photophobia after three cycles of ICPI therapy comprised of ipilimumab and nivolumab. Bilateral anterior uveitis, multiple left ey

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23

Abid, Hatim. "Lupus Vorax: A Cause of Centrofaciale Mutilation." Journal of Clinical and Medical Research, June 3, 2021. http://dx.doi.org/10.37191/mapsci-2582-4333-3(4)-075.

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Cutaneous tuberculosis is an infectious disease that is still endemic in developing countries and constitutes even in large cities of developed countries a serious public health issue. Clinical forms are numerous and, in this context, centrofacial location represents in addition to diagnostic difficulties, a real prognostic problem. We report in the light of a literature review, 2 cases of centrofacial mutilation secondary to cutaneous tuberculosis in its ulcerative and vegetating presentation also called lupus vorax to remind this rare paucibacillary form whose early diagnosis influences cons

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24

"Iris Melanoma-A Rare Ocular Tumour." Medicine & Health 20, no. 1 (2025): 366–74. https://doi.org/10.17576/mh.2025.2001.24.

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Uveal melanoma is a rare condition, especially in the Asian population that can be overlooked as a diagnostic consideration, leading to delayed identification. We reported the case of a 69-year-old Chinese man who presented with an iris mass that was initially treated as a cyst. The mass continued to grow in size, which raised suspicion of other infective causes or malignancy. Following the initial uveitic workup, the patient was found to be positive for QuantiFERON-TB test. Tumour markers and chest X-rays were unremarkable. The patient was treated for iris granuloma secondary to tuberculosis.

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25

Leya, Marysa, Ike Okwuosa, Jon W. Lomasney, et al. "Abstract 15578: Propionibacterium Acnes -associated Cardiac Sarcoidosis Presenting as Constrictive Pericarditis." Circulation 142, Suppl_3 (2020). http://dx.doi.org/10.1161/circ.142.suppl_3.15578.

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Sarcoidosis is an antigen-mediated chronic multisystem inflammatory disease characterized by the formation of non-caseating epithelioid granulomas that disrupt tissue architecture, trigger fibrosis, and precipitate organ dysfunction. Cardiac involvement portends a poorer prognosis, presenting with conduction disease, heart failure, pulmonary hypertension, valvular disease, pericardial effusions, tamponade, ventricular arrhythmias, and sudden death. A 75-year-old man with a history of heart failure with mildly reduced ejection fraction, suspected ocular sarcoidosis, monoclonal gammopathy of unc

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26

Kreinbrink, Jessica, Andrew Weibel, and Katherine Weibel. "Bilateral Optic Disc Drusen with Neuroretinitis." Optometric Clinical Practice 4, no. 2 (2022). http://dx.doi.org/10.37685/uiwlibraries.2575-7717.4.2.1050.

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Background: Neuroretinitis is an inflammation of the posterior pole of the eye, resulting in optic disc edema and macular star formation. Systemic conditions associated with these findings include tuberculosis, toxoplasmosis, syphilis, lyme disease, toxocariasis, mumps, herpes simplex, and cat scratch disease. This case illustrates diagnosis and treatment for a patient with neuroretinitis complicated by preexisting vision loss. Case Report: A Caucasian male in his 40’s presented to the eye clinic for an emergency appointment with complaints of constant blurry vision, especially inferiorly upon

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