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Journal articles on the topic 'Secondary Palate'

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1

Ortiz-Posadas, M. R., L. Vega-Alvarado, and J. Maya-Behar. "A New Approach to Classify Cleft Lip and Palate." Cleft Palate-Craniofacial Journal 38, no. 6 (2001): 545–50. http://dx.doi.org/10.1597/1545-1569_2001_038_0545_anatcc_2.0.co_2.

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Objective: To propose a new method, which allows for a complete description of primary and secondary cleft palates, incorporating elements that are related to the palate, lip, and nose that will also reflect the complexity of this problem. Method: To describe the type of cleft, two embryonic structures were considered: (1) the primary palate, formed by the prolabium, premaxilla, and columella and (2) the secondary palate, which begins at the incisive foramen and is formed by a horizontal portion of the maxilla, the horizontal portion of the palatine bones, and the soft palate. Anatomical chara
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2

Taney, Kendall. "Secondary Cleft Palate Repair." Journal of Veterinary Dentistry 25, no. 2 (2008): 150–53. http://dx.doi.org/10.1177/089875640802500220.

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3

Oliveira, Giovanna Carolina Rothert de, Rafael Ricardo Huppes, and Ivan Torres Gregorio da Silva. "Secondary cleft palate correction with 3D-printed thermoplastic polyurethane film – a case report." Acta Scientiarum. Animal Sciences 46 (August 16, 2024): e67125. http://dx.doi.org/10.4025/actascianimsci.v46i1.67125.

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Cleft palate is an oronasal communication that can affect the area comprehending the lips and the soft palate. Its clinical signs vary depending on the degree of the defect and the age of the animal, ranging from nasal secretion, coughing, sneezing, halitosis, respiratory difficulty, aspiration pneumonia, and loss of body condition. Its diagnosis is based on inspection of the oral cavity and imaging tests. Palatal defects must be surgically corrected as quickly as possible, using mucosal flaps, grafts, or implants. A desire to evolve alternative treatments for cleft palates drives the search f
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4

Sitzman, Thomas J., Adam C. Carle, Pamela C. Heaton, Michael A. Helmrath, and Maria T. Britto. "Five-Fold Variation Among Surgeons and Hospitals in the Use of Secondary Palate Surgery." Cleft Palate-Craniofacial Journal 56, no. 5 (2018): 586–94. http://dx.doi.org/10.1177/1055665618799906.

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Objective: To identify child-, surgeon- and hospital-specific factors at the time of primary cleft palate repair that are associated with the use of secondary palate surgery. Design: Retrospective cohort study. Setting: Forty-nine pediatric hospitals. Participants: Children who underwent cleft palate repair between 1998 and 2015. Main Outcome Measure: Time from primary cleft palate repair to secondary palate surgery. Results: By 5 years after the primary palate repair, 27.5% of children had undergone secondary palate surgery. In multivariable analysis, cleft type and age at primary palate repa
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5

Banks, P. "Secondary bone grafts (alveolus, palate)." British Journal of Plastic Surgery 42, no. 3 (1989): 353–54. http://dx.doi.org/10.1016/0007-1226(89)90165-3.

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6

Monson, Laura A., David Y. Khechoyan, Edward P. Buchanan, and Larry H. Hollier. "Secondary Lip and Palate Surgery." Clinics in Plastic Surgery 41, no. 2 (2014): 301–9. http://dx.doi.org/10.1016/j.cps.2013.12.008.

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7

Sitzman, Thomas J., Alexander C. Allori, Damir B. Matic, et al. "Reliability of Oronasal Fistula Classification." Cleft Palate-Craniofacial Journal 55, no. 6 (2018): 871–75. http://dx.doi.org/10.1597/16-186.

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Objective: Oronasal fistula is an important complication of cleft palate repair that is frequently used to evaluate surgical quality, yet reliability of fistula classification has never been examined. The objective of this study was to determine the reliability of oronasal fistula classification both within individual surgeons and between multiple surgeons. Design: Using intraoral photographs of children with repaired cleft palate, surgeons rated the location of palatal fistulae using the Pittsburgh Fistula Classification System. Intrarater and interrater reliability scores were calculated for
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8

Sasaki, Y., S. Tanaka, T. Hamachi, and Y. Taya. "Deficient Cell Proliferation in Palatal Shelf Mesenchyme of CL/Fr Mouse Embryos." Journal of Dental Research 83, no. 10 (2004): 797–801. http://dx.doi.org/10.1177/154405910408301012.

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How secondary palate formation is affected in the cleft lip genotype remains poorly understood. The purpose of this study was to analyze regional patterns of cell proliferation in CL/Fr mouse embryos with or without cleft lip. Pairs of palatal shelves were dissected at E13.5 from CL/Fr normal embryos (CL/Fr-N), CL/Fr embryos with bilateral cleft lip (CL/Fr-BCL), and a control strain of C57BL embryos (C57BL). The explants were examined histologically after 48 hrs of organ culture. Cell kinetics for proliferation in the palatal shelves was examined at E13.5 by the bromodeoxyuridine method in viv
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9

Gregg, Terry, Dorothy Boyd, and Andrew Richardson. "The Incidence of Cleft Lip and Palate in Northern Ireland from 1980–1990." British Journal of Orthodontics 21, no. 4 (1994): 387–92. http://dx.doi.org/10.1179/bjo.21.4.387.

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This study reports the incidence of the various types of cleft lip and/or palate drawn from a regional database of all affected children born in Northern Ireland during the period 1980–1990. The incidence of these anomalies was 1·28 per 1000 live births (1:781). Fifty-three per cent of clefts involved the secondary palate only, 16 per cent the primary palate only, 26 per cent involved both primary and secondary palate, and 5 per cent were unconnected. Overall, more males than females were affected and there were more males than females in the group having complete clefts. Separate clefts of li
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10

Liu, Jia, Jing Chen, Dong Yuan, et al. "Dynamic mRNA Expression Analysis of the Secondary Palatal Morphogenesis in Miniature Pigs." International Journal of Molecular Sciences 20, no. 17 (2019): 4284. http://dx.doi.org/10.3390/ijms20174284.

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Normal mammalian palatogenesis is a complex process that requires the occurrence of a tightly regulated series of specific and sequentially regulated cellular events. Cleft lip/palate (CLP), the most frequent craniofacial malformation birth defects, may occur if any of these events undergo abnormal interference. Such defects not only affect the patients, but also pose a financial risk for the families. In our recent study, the miniature pig was shown to be a valuable alternative large animal model for exploring human palate development by histology. However, few reports exist in the literature
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11

Merry, AJ, CS Potten, and Mwj Ferguson. "Cell Proliferation during Secondary Palate Development." Clinical Science 87, s31 (1994): 40P—41P. http://dx.doi.org/10.1042/cs045040pc_pt2.

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12

Gritli-Linde, Amel. "Molecular control of secondary palate development." Developmental Biology 301, no. 2 (2007): 309–26. http://dx.doi.org/10.1016/j.ydbio.2006.07.042.

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13

Logan, Shaun M., L. Bruno Ruest, M. Douglas Benson, and Kathy K. H. Svoboda. "Extracellular Matrix in Secondary Palate Development." Anatomical Record 303, no. 6 (2019): 1543–56. http://dx.doi.org/10.1002/ar.24263.

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14

Bulleit, Robert F., and Ernest F. Zimmerman. "The effect of reducing ATP levels on reorientation of the secondary palate." Development 93, no. 1 (1986): 73–84. http://dx.doi.org/10.1242/dev.93.1.73.

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The force for directing palate shelf reorientation appears to be associated with elements of the presumptive hard palate (Brinkley & Vickerman, 1979; Bulleit & Zimmerman, 1985). The palatal elements that mediate this process do not require palate cells to be metabolically active for expression of the force. This contention was demonstrated using an in vitro system that allows substantial reorientation of the hard palate to occur. ATP levels were reduced by treatment with metabolic inhibitors and the degree of reorientation was measured 1 h following pretreatment with inhibitors. Treatm
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15

Deshmukh, Mazin M., and Gaurav Deshpande. "Musculomucosal Flap: A Technique for Correction of Velopharyngeal Insufficiency by Palate Lengthening." Journal of Contemporary Dentistry 7, no. 3 (2017): 174–77. http://dx.doi.org/10.5005/jp-journals-10031-1209.

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ABSTRACT A small but significant percentage of patients have inadequate velopharyngeal closure, or secondary velopharyngeal incompetence, following primary palatoplasty. The use of the buccinator musculomucosal (MM) flap has been described for both primary palate repair with lengthening and secondary palate lengthening for the correction of insufficient velopharyngeal closure. The MM flap was first described in 1969 for the primary repair of a wide cleft palate by Mukherji, and it was Bozola et al in 1989 who first formally described it and gave first description of its anatomy. The first repo
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16

Dhulipala, Vamsidhara C., Wade V. Welshons, and Chada S. Reddy. "Cell cycle proteins in normal and chemically induced abnormal secondary palate development: a review." Human & Experimental Toxicology 25, no. 11 (2006): 675–82. http://dx.doi.org/10.1177/0960327106070848.

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Cell cycle progression and thus proper cell number is essential for normal development of organs and organisms. Craniofacial tissues including the secondary palate are vulnerable to disruption of cell cycle progression and proliferation by many chemicals including mycotoxin, secalonic acid D (SAD), glucocorticoids, retinoic acid and 2,3,7,8-tetrachlorodibenzodioxin. Induction of cleft palate (CP) by SAD in mice occurs from a reduction in the size of developing palatal shelves. This is associated with an inhibition of proliferation of murine and human embryonic palatal mesenchymal (MEPM and HEP
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17

Abdulai, E. R., K. K. Baidoo, A. A. Jangu, K. Searyoh, and Y. Ahonon. "Assessment Of Hearing Threshold Among Post Repaired Cleft Palate Patients In Korle-Bu Teaching Hospital, Ghana." Postgraduate Medical Journal of Ghana 9, no. 2 (2022): 82–89. http://dx.doi.org/10.60014/pmjg.v9i2.231.

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Objective: The aim of the study was to assess the hearing threshold in patients with repaired cleft palate and to determine the degree of hearing loss in various types of cleft palate.Methods: This was a cross-sectional study which was conducted on 97 consenting patients with clinical diagnosis of repaired cleft palate at the Plastic and Reconstructive surgery unit, Korle Bu Teaching Hospital. The hearing loss threshold levels in the rightand left cleft palates were then compared using Chisquare test of independence.Results: A total of 97 participants who had cleft palate were seen that is 194
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18

Risandy, Ditia Widhani, Jilvientasia, Utami Gladya, et al. "The Evaluation of Hospital Social Responsibility Services in Gatot Soebroto Indonesia Central Army Hospital in 2015 – 2019 of Cleft Lip and Palate Patients." International Journal Of Medical Science And Clinical Research Studies 02, no. 11 (2022): 1346–50. https://doi.org/10.5281/zenodo.7354951.

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<strong>Background :&nbsp;</strong>Cleft lip and cleft palate are the most common congenital craniofacial anomalies treated by plastic surgeons. The incidence of cleft lip and palate is higher at lower socioeconomic levels. Hospital Social Responsibility (HSR) in Gatot Soebroto Central Army Hospital provides free cleft lip and palate surgeries to those who need it the most. The HSR services still need to be evaluated, to get an overview of epidemiologic profile of cleft lip and palate patients, and to improve the services itself. &nbsp; <strong>Materials and Method:&nbsp;</strong>The authors c
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19

Oberoi, Snehlata, Radhika Chigurupati, Pawandeep Gill, William Y. Hoffman, and Karin Vargervik. "Volumetric Assessment of Secondary Alveolar Bone Grafting Using Cone Beam Computed Tomography." Cleft Palate-Craniofacial Journal 46, no. 5 (2009): 503–11. http://dx.doi.org/10.1597/08-153.1.

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Objective: To assess the radiographic outcome of secondary alveolar bone grafting in individuals with nonsyndromic unilateral or bilateral cleft lip and palate using cone beam computed tomography. Methods: This prospective study was conducted at the University of California at San Francisco Center for Craniofacial Anomalies on 21 consecutive nonsyndromic complete cleft lip and palate individuals between 8 and 12 years of age who required alveolar bone grafting. Seventeen unilateral and four bilateral cleft lip and palate individuals had preoperative and postoperative cone beam computed tomogra
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20

Thorley, DS, AR Simons, O. Mirza, and V. Malik. "Palatal and retropharyngeal injury secondary to intubation using the GlideScope® video laryngoscope." Annals of The Royal College of Surgeons of England 97, no. 4 (2015): e67-e69. http://dx.doi.org/10.1308/003588415x14181254789727.

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Introduction There are few reports of injury to the soft palate and retropharynx sustained during intubation with the GlideScope® video laryngoscope. Most reports are of isolated injury to the soft palate. Case History We describe a patient in whom the retropharynx was injured but the extent of the injury was not observed initially. The patient did not suffer severe sequelae from this injury. However, this injury can cause serious sequelae if it is not recognised (eg development of a retropharyngeal abscess). Conclusions We recommend that any patient who sustains injury to the soft palate duri
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21

Rajendra, Nehete, Nehete Anita, Singla Nehete, and Sankalecha Sudhir. "Soft tissue chondroma of hard palate associated with cleft palate." Indian Journal of Plastic Surgery 45, no. 03 (2012): 550–52. http://dx.doi.org/10.4103/0970-0358.105974.

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ABSTRACTSoft tissue chondroma of palate is very rare. It has never been reported in a cleft palate patient. We report a case of 22-year-old male who came with asymptomatic swelling on the palate since birth, along with complete cleft of secondary palate. He had symptoms related to cleft palate only, i.e., nasal regurgitation and speech abnormalities. Swelling was excised and the cleft palate was repaired. Histopathological examination revealed chondroma of the palate. The patient had no recurrence after 2 years of follow-up.
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22

Mitic, Vladimir, Marina Jonovic, Nadica Mitic, et al. "Incidence of lip and palate clefts in children in Nis from 1990 to 2007." Srpski arhiv za celokupno lekarstvo 139, no. 5-6 (2011): 298–303. http://dx.doi.org/10.2298/sarh1106298m.

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Introduction. Cleft lip and palate is a complex congenital anomaly of the orofacial system in children. Objective. The aim of this study was to determine the incidence of live-born children with cleft lip and/or palate compared to the total number of children born in the period from January 1, 1990 to December 31, 2007. Methods. Epidemiological investigation was based on the records of live-born children at the Hospital of Gynaecology and Obstetrics of the Clinical Centre Nis. The study included 61,116 live-born children, i.e. 56,905 full-term babies. Results. The total number of registered cl
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23

Goodwin, A. F., C. P. Chen, N. T. Vo, J. O. Bush, and O. D. Klein. "YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate." Journal of Dental Research 99, no. 12 (2020): 1387–96. http://dx.doi.org/10.1177/0022034520935372.

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Clefting of the secondary palate is one of the most common congenital anomalies, and the multiple corrective surgeries that individuals with isolated cleft palate undergo are associated with major costs and morbidities. Secondary palate development is a complex, multistep process that includes the elevation of the palatal shelves from a vertical to horizontal position, a process that is not well understood. The Hippo signaling cascade is a mechanosensory pathway that regulates morphogenesis, homeostasis, and regeneration by controlling cell proliferation, apoptosis, and differentiation, primar
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Warner, Dennis R., Partha Mukhopadhyay, Cindy L. Webb, Robert M. Greene, and M. Michele Pisano. "Chromatin immunoprecipitation-promoter microarray identification of genes regulated by PRDM16 in murine embryonic palate mesenchymal cells." Experimental Biology and Medicine 237, no. 4 (2012): 387–94. http://dx.doi.org/10.1258/ebm.2012.011258.

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The transcription factor PRDM16 regulates differentiation of brown adipocyte tissue in mice. Recently, however, it has been demonstrated that genetic knockout of Prdm16 in mice leads to a complete cleft of the secondary palate in offspring. To identify genes whose promoters bind PRDM16 in mouse embryonic palate/maxillary mesenchymal cells, we have conducted a chromatin immunoprecipitation-promoter microarray analysis (ChIP-Chip). One hundred and twenty-two gene promoters were identified as capable of binding PRDM16. These could be functionally grouped to include those on genes linked to muscle
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25

Bulleit, Robert F., and Ernest F. Zimmerman. "The influence of the epithelium on palate shelf reorientation." Development 88, no. 1 (1985): 265–79. http://dx.doi.org/10.1242/dev.88.1.265.

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The intrinsic forces necessary for directing the reorientation of the secondary palate appear to reside in the anterior two thirds of the palate or presumptive hard palate. The hard palate could reorient regardless of whether it was intact or separated from the posterior third or presumptive soft palate. The soft palate could only reorient if the palate shelves are left intact. These intrinsic forces, within the hard palate, may be mediated by the mesenchymal cells, their extracellular matrix, or the epithelium surrounding the shelves. This latter possibly was tested by removing the epithelium
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Brinkley, Linda L., and Fred L. Bookstein. "Cell distribution during mouse secondary palate closure." Development 96, no. 1 (1986): 111–30. http://dx.doi.org/10.1242/dev.96.1.111.

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The patterns of distribution of both total mesenchymal cells and the ratios of [3H]thymidinelabelled to total cells were mapped during secondary palatal shelf reorientation in vivo and in vitro. Smoothed spatial averaging, a computer-assisted method which takes into account the positions of all cells across an entire histological section of the shelf, was employed. Changes in shelf cross-sectional area and cell size were also measured. Three shelf regions, anterior and posterior presumptive hard and presumptive soft palate, were studied at developmental stages which were 30, 24 and 18 h prior
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SHAH, RAVINDRA M., DWAYNE M. OGASAWARA, and KIMBERLY M. CHENG. "Embryogenesis of the Secondary Palate in Pigeons." Poultry Science 67, no. 6 (1988): 865–70. http://dx.doi.org/10.3382/ps.0670865.

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28

Seelan, R. S., P. Mukhopadhyay, M. M. Pisano, and R. M. Greene. "Developmental Epigenetics of the Murine Secondary Palate." ILAR Journal 53, no. 3-4 (2012): 240–52. http://dx.doi.org/10.1093/ilar.53.3-4.240.

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29

Takato, Tsuyoshi. "Secondary Rhinoplasty for Cleft Lip and Palate." Journal of Oral and Maxillofacial Surgery 65, no. 9 (2007): 20–21. http://dx.doi.org/10.1016/j.joms.2007.06.059.

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Cintra, Henrique Ladvocat, Filipe V. Basile, Tatiana T. Tournieux, Ivo Pitanguy, and Antonio Roberto Basile. "Midline palate perforation secondary to cocaine abuse." Journal of Plastic, Reconstructive & Aesthetic Surgery 61, no. 5 (2008): 588–90. http://dx.doi.org/10.1016/j.bjps.2007.08.028.

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31

Nemec, A., L. Barinka, and V. Simecek. "Secondary bone graft implantation in cleft palate." Plastic and Reconstructive Surgery 81, no. 1 (1988): 144. http://dx.doi.org/10.1097/00006534-198801000-00060.

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32

Thaller, Seth R. "Staged Repair of Secondary Cleft Palate Deformities." Journal of Craniofacial Surgery 6, no. 5 (1995): 375–79. http://dx.doi.org/10.1097/00001665-199509000-00008.

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33

Campbell, S. "Prenatal ultrasound examination of the secondary palate." Ultrasound in Obstetrics and Gynecology 29, no. 2 (2007): 124–27. http://dx.doi.org/10.1002/uog.3954.

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34

Ermiş, Ayşe Gizem, and Mehmet Can. "Morphological characterization of hard palate in the Tabby cats." Revista Científica de la Facultad de Ciencias Veterinarias XXXIII, no. 2 (2023): 1–7. http://dx.doi.org/10.52973/rcfcv-e33285.

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The aim of this study was to carry out the morphological characterization of the Tabby cat’s hard palate by light and scanning electron microscopy (SEM), in addition to gross and morphometric analysis. A total of 20 Tabby cat heads used. The materials was provided from the Balıkesir Metropolitan Municipality Street Animals Temporary Nursing Home and Rehabilitation Center, Balıkesir, Turkey. Adult, regardless of gender difference, died from variety of reasons and 20 Tabby cat cadavers which weigh approximately 3–4 kg were brought to the laboratory in accordance with the procedure. Hard palates
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Lough, K. J., K. M. Byrd, D. C. Spitzer, and S. E. Williams. "Closing the Gap: Mouse Models to Study Adhesion in Secondary Palatogenesis." Journal of Dental Research 96, no. 11 (2017): 1210–20. http://dx.doi.org/10.1177/0022034517726284.

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Secondary palatogenesis occurs when the bilateral palatal shelves (PS), arising from maxillary prominences, fuse at the midline, forming the hard and soft palate. This embryonic phenomenon involves a complex array of morphogenetic events that require coordinated proliferation, apoptosis, migration, and adhesion in the PS epithelia and underlying mesenchyme. When the delicate process of craniofacial morphogenesis is disrupted, the result is orofacial clefting, including cleft lip and cleft palate (CL/P). Through human genetic and animal studies, there are now hundreds of known genetic alternati
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Brennan, Tara, Tristan Tham, and Peter Costantino. "The Temporalis Muscle Flap for Palate Reconstruction: Case Series and Review of the Literature." International Archives of Otorhinolaryngology 21, no. 03 (2017): 259–64. http://dx.doi.org/10.1055/s-0037-1598653.

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Introduction The temporalis myofascial (TM) is an important reconstructive flap in palate reconstruction. Past studies have shown the temporalis myofascial flap to be safe as well as effective. Free flap reconstruction of palate defects is also a popular method used by contemporary surgeons. We aim to reaffirm the temporalis myofascial flap as a viable alternative to free flaps for palate reconstruction. Objective We report our results using the temporalis flap for palate reconstruction in one of the largest case series reported. Our literature review is the first to describe complication rate
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Kuzniak, Nataliya B., Roman R. Dmytrenko, Larysa Ya Fedoniuk, et al. "DEVELOPMENT OF THE INNER NASAL CAVITY IN ANIMALS IN PHYLO- AND ONTOGENESIS: FUNCTIONAL ANATOMIC SIGNIFICANCE IN THE DEVELOPMENT PERIOD." Wiadomości Lekarskie 72, no. 3 (2019): 432–35. http://dx.doi.org/10.36740/wlek201903121.

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Іntroduction: Main functions of the inner nose in humans are respiration and olfaction. Therefore, human needs a large surface of inhalable and exhalable air contact, warming and moistening. Importance of these organs in animals in phylogenesis before and after the secondary palate development can explain their anatomic and functional designation. The aim is to find out the functional significance of some anatomic formations of the inner nose and their development peculiarities in phylo-and ontogenesis. Materials and methods: We used a comparative anatomy method where we compared well-known fa
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Sundoro, Ali, Dany Hilmanto, Hardisiswo Soedjana, Ronny Lesmana, and Selvy Harianti. "Epidemiology of cleft lip and palate charity mission surgery at Bandung Cleft Lip and Palate Center, Indonesia: a 14-year institutional review." Archives of Craniofacial Surgery 25, no. 2 (2024): 62–70. http://dx.doi.org/10.7181/acfs.2023.00416.

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Background: The management of cleft lip and palate aims at improving the patient’s aesthetic and functional outcomes. Delaying primary repair can disrupt the patient’s functional status. Long-term follow-up is essential to evaluate the need for secondary repair or revision surgery. This article presents the epidemiology of cleft lip and palate, including comprehensive patient characteristics, the extent of delay, and secondary repair at our institutional center, the Bandung Cleft Lip and Palate Center, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.Methods: This retrospective
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Smith, Darren M., Lisa Vecchione, Shao Jiang, et al. "The Pittsburgh Fistula Classification System: A Standardized Scheme for the Description of Palatal Fistulas." Cleft Palate-Craniofacial Journal 44, no. 6 (2007): 590–94. http://dx.doi.org/10.1597/06-204.1.

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Objective: Vague terminology is a problem in cleft palate research. No classification scheme for palatal fistulas has been proposed to date. Although a well-healed velum is a significant outcome of palatoplasty, it is nearly impossible to compare fistula-related palatoplasty results in the literature or in medical records without a standardized vocabulary. We endeavor to devise a palatal fistula classification system that may have clinical and research applicability. Design: PubMed was searched for definitions and classifications of palatal fistula as well as incidence and recurrence rates of
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40

Li, C., Y. Lan, R. Krumlauf, and R. Jiang. "Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice." Journal of Dental Research 96, no. 11 (2017): 1273–81. http://dx.doi.org/10.1177/0022034517719865.

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Cleft palate is a common birth defect caused by disruption of palatogenesis during embryonic development. Although mutations disrupting components of the Wnt signaling pathway have been associated with cleft lip and palate in humans and mice, the mechanisms involving canonical Wnt signaling and its regulation in secondary palate development are not well understood. Here, we report that canonical Wnt signaling plays an important role in Pax9-mediated regulation of secondary palate development. We found that cleft palate pathogenesis in Pax9-deficient embryos is accompanied by significantly redu
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Mukhopadhyay, Partha, Irina Smolenkova, Dennis Warner, Michele M. Pisano, and Robert M. Greene. "Spatio-Temporal Expression and Functional Analysis of miR-206 in Developing Orofacial Tissue." MicroRNA 8, no. 1 (2018): 43–60. http://dx.doi.org/10.2174/2211536607666180801094528.

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Background:Development of the mammalian palate is dependent on precise, spatiotemporal expression of a panoply of genes. MicroRNAs (miRNAs), the largest family of noncoding RNAs, function as crucial modulators of cell and tissue differentiation, regulating expression of key downstream genes. &lt;/P&gt;&lt;P&gt; Observations: Our laboratory has previously identified several developmentally regulated miRNAs, including miR-206, during critical stages of palatal morphogenesis. The current study reports spatiotemporal distribution of miR-206 during development of the murine secondary palate (gestat
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McCance, Andrew, David Roberts-Harry, Martyn Sherriff, Michael Mars, and William J. B. Houston. "Sri Lankan Cleft Lip and Palate Study Model Analysis: Clefts of the Secondary Palate." Cleft Palate-Craniofacial Journal 30, no. 2 (1993): 227–30. http://dx.doi.org/10.1597/1545-1569(1993)030<0227:slclap>2.3.co;2.

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43

Mccance, Andrew, David Roberts-Harry, Martyn Sherriff, Michael Mars, and William J. B. Houston. "Sri Lankan Cleft Lip and Palate Study Model Analysis: Clefts of the Secondary Palate." Cleft Palate-Craniofacial Journal 30, no. 2 (1993): 227–30. http://dx.doi.org/10.1597/1545-1569_1993_030_0227_slclap_2.3.co_2.

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The study models of a group of adult Sri Lankan patients with clefts of the secondary palate were investigated. Tooth-size and arch-dimension comparisons were made with a comparable control group. Significant differences were found between the cleft and control groups in tooth sizes, chord lengths, and arch widths. The cleft group dimensions were generally smaller than those of the control group. Overjets were larger in the cleft group.
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44

Jin, Jiu-Zhen, Zhenmin Lei, Zi-Jian Lan, Partha Mukhopadhyay, and Jixiang Ding. "Inactivation of Fgfr2 gene in mouse secondary palate mesenchymal cells leads to cleft palate." Reproductive Toxicology 77 (April 2018): 137–42. http://dx.doi.org/10.1016/j.reprotox.2018.03.004.

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45

Romero, Martín, Ralph Latham, Ana Romance, and Rafael Salvan. "Treatment of an Infant with a Rare Cleft Resolved with Use of an Orthopedic Appliance." Cleft Palate-Craniofacial Journal 40, no. 6 (2003): 642–44. http://dx.doi.org/10.1597/02-106.

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Objective Cases of bilateral complete clefts of the primary palate and unaffected secondary palate are very rare. One of these cases as well as a new method of presurgical orthopedics to solve the protruding premaxilla protrusion is presented.
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46

Ferguson, Mark W. J. "Palate development." Development 103, Supplement (1988): 41–60. http://dx.doi.org/10.1242/dev.103.supplement.41.

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In all vertebrates, the secondary palate arises as bilateral outgrowths from the maxillary processes. In birds and most reptiles, these palatal shelves grow initially horizontally, but do not fuse with each other resulting in physiological cleft palate. In crocodilians, shelf fusion occurs resulting in an intact secondary palate. Mammalian palatal shelves initially grow vertically down the side of the tongue, but elevate at a precise time to a horizontal position above the dorsum of the tongue and fuse with each other to form an intact palate. Palatal shelf-elevation is the result of an intrin
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Mayo, Robert, Rodger M. Dalston, and Donald W. Warren. "Perceptual Assessment of Resonance Distortion in Unoperated Clefts of the Secondary Palate." Cleft Palate-Craniofacial Journal 30, no. 4 (1993): 397–400. http://dx.doi.org/10.1597/1545-1569_1993_030_0307_paordi_2.3.co_2.

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The purpose of this study was to examine the frequency with which five speech-language pathologists made judgments of hypernasality during the clinical assessment of young children with unoperated and repaired clefts of the secondary palate. Among the 293 nonsyndromic patients with secondary palate clefts included in this study, 219 were between 1 and 2 years of age. Of those, 83 had undergone primary palatoplasty whereas 136 had not. The remaining 74 children were between the ages of 4 and 5 years and presented with repaired secondary palatal clefts. The results showed that the clinicians wer
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Beckman, Brett. "Repair of Secondary Cleft Palate in the Dog." Journal of Veterinary Dentistry 28, no. 1 (2011): 58–62. http://dx.doi.org/10.1177/089875641102800114.

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Teng, Teng, and Jeffrey Bush. "Collective epithelial cell migration in secondary palate fusion." FASEB Journal 34, S1 (2020): 1. http://dx.doi.org/10.1096/fasebj.2020.34.s1.06292.

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Grist, Fiona. "Secondary surgery in cleft lip and palate care." Dental Nursing 5, no. 4 (2009): 212–14. http://dx.doi.org/10.12968/denn.2009.5.4.41083.

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