Academic literature on the topic 'Sedative drugs namely benzodiazepines'

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Journal articles on the topic "Sedative drugs namely benzodiazepines"

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Muralinath, E., Devi Pooja, Ch. Nath Nikhil, et al. "Exploring Medications for Managing Sleeping Disorders." Advanced Research and Reviews in Geriatric Nursing & Health Sciences 1, no. 1 (2024): 11–15. https://doi.org/10.5281/zenodo.10656317.

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<em>Sleeping disorders influence a significant portion of the global population, affecting overall wellbeing and daily functioning, Benzodiazepines namely bdiazepam and lorazepam behave as central nervous system depressants. They increase the effects of gamma_ amino butyric acid (GABA), a neurotransmitter that causes relaxation as well as sedation. Non _ benzodiazipine hypnotic (Z _ drug) namely zolpidem and zaleplon target GABA receptors and induce a calming effect along with promotion of sleep. Z _ drugs are helpful for treating insomnia. A very few drugs namely ramelteon and tasimelteon mim
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Muralinath, E., Devi Pooja, Chbukdhara Prasanta, et al. "The Impact of Drugs on Muscle Relaxants: A Comprehensive Analysis." Research and Reviews: Journal of Wound, Ostomy and Continence Nursing 2, no. 1 (2023): 1–5. https://doi.org/10.5281/zenodo.10398876.

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<em>Muscle relaxants ate helpful on decreasing muscle spasms, pain and stiffness also. Muscle relaxants perform by affecting the Central nervous system and decrease nerve impulses that are responsible for causing muscle contractions. Muscle relaxants are frequently prescribed for a very few conditions namely chronic pain, Muscle spasms and certain neurological abnormalities. An example for common Muscle relaxants is baclofenac, cyclobenzaprine and tizanide. If alcohol combines with Muscle relaxants, It can enhance dizziness and drowsiness also. This interaction results in impairment of motor s
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Dasgupta, Arup, Sayandev Dasgupta, Supratik Sen, Sukanta Sen, and Girish Kishore Sinha. "Benzodiazepine hypnotics as oral preanaesthetic medication: a comparative clinical study." International Surgery Journal 4, no. 1 (2016): 304. http://dx.doi.org/10.18203/2349-2902.isj20164460.

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Background:An ideal pre-medicant should allay fear and anxiety without producing its effect on vital functions of the body and body chemistry, with minimal depression of the respiratory and circulatory systems. The ideal pre-medicant with all good qualities and no side effects at all is yet to be found. The search for a drug which will be an appropriate pre-anesthetic medication is still going.Methods: Four drugs of BZD group namely diazepam, nitrazepam, lorazepam, and oxazepam were chosen as oral pre-anesthetic medication. Total number of cases were 100, of which 25 patients belonging to each
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Muralinath, E., H.S. Singh, Digamber D. Vijay, et al. "Understanding the Connection between Drugs and Lobular Pneumonia." Journal of Advances in Ayurveda, Yoga, Homeopathy and Naturopathy 2, no. 1 (2024): 10–12. https://doi.org/10.5281/zenodo.10622835.

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<em>Lobular pneumonia, also termed as broncho pneumonia, is a type of pneumonia that influences multiple areas of the lungs. Bacterial and viral infections result in lobular pneumonia. Corticosteroids or immuno suppressive agents may enhance the risk of lobular pneumonia. In some cases, Non_steroidal anti_ inflammatory drugs (NSAID,s) can result in drug_ induced pneumonia, along with the lobular pneumonia subtype. Antibiotics sometimes can result in pneumonia. Benzodiazepines (sedative drug) can enhance the risk of aspiration pneumonia. Immunization against preventable respiratory infections,
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Ríos, José-Luis, Guillermo R. Schinella, and Inés Moragrega. "Phenolics as GABAA Receptor Ligands: An Updated Review." Molecules 27, no. 6 (2022): 1770. http://dx.doi.org/10.3390/molecules27061770.

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Natural products can act as potential GABA modulators, avoiding the undesirable effects of traditional pharmacology used for the inhibition of the central nervous system such as benzodiazepines (BZD). Phenolics, especially flavonoids and phlorotannins, have been considered as modulators of the BZD-site of GABAA receptors (GABAARs), with sedative, anxiolytic or anticonvulsant effects. However, the wide chemical structural variability of flavonoids shows their potential action at more than one additional binding site on GABAARs, which may act either negatively, positively, by neutralizing GABAAR
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Tashrifi, Zahra, Mohammad Mohammadi-Khanaposhtani, Mahmood Biglar, Bagher Larijani, and Mohammad Mahdavi. "Isatoic Anhydride: A Fascinating and Basic Molecule for the Synthesis of Substituted Quinazolinones and Benzo di/triazepines." Current Organic Chemistry 23, no. 10 (2019): 1090–130. http://dx.doi.org/10.2174/1385272823666190701142930.

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This review article is focused on the synthesis of compounds with quinazolinones and benzo di/triazepine scaffolds. These invaluable derivatives are of great interest in medicinal and pharmaceutical studies because of their important biological properties. Quinazolinones have diverse applications due to their antibacterial, analgesic, antiinflammatory, antifungal, antimalarial, antihypertensive, CNS depressant, anticonvulsant, antihistaminic, antiparkinsonism, antiviraland and anticancer activities. On the other hand, pharmacological properties of benzodiazepines include antianxiety, anticance
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Joshi, Mahima, Javed Muneer, Lawrence Mbuagbaw, and Ipsita Goswami. "Analgesia and sedation strategies in neonates undergoing whole-body therapeutic hypothermia: A scoping review." PLOS ONE 18, no. 12 (2023): e0291170. http://dx.doi.org/10.1371/journal.pone.0291170.

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Background Therapeutic hypothermia (TH) is a widely practiced neuroprotective strategy for neonates with hypoxic-ischemic encephalopathy. Induced hypothermia is associated with shivering, cold pain, agitation, and distress. Objective This scoping review determines the breadth of research undertaken for pain and stress management in neonates undergoing hypothermia therapy, the pharmacokinetics of analgesic and sedative medications during hypothermia and the effect of such medication on short- and long-term neurological outcomes. Methods We searched the following online databases namely, (i) MED
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Vitukade, Ganesh Anil. "A Systematic Review on Sedative and Hypnotics." International Journal for Research in Applied Science and Engineering Technology 12, no. 7 (2024): 671–81. http://dx.doi.org/10.22214/ijraset.2024.63593.

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Abstract: Sedative and hypnotic drugs are central nervous system depressants primarily used to induce calmness, reduce anxiety, and promote sleep. These medications include benzodiazepines, barbiturates, and various non-benzodiazepine sleep aids, each varying in their mechanism of action, efficacy, and safety profiles. Benzodiazepines, such as diazepam and alprazolam, enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, resulting in sedative, anxiolytic, muscle relaxant, and anticonvulsant effects. They are commonly prescribed for anxiety disorders,
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Lader, M. "DB03-01 - We still need benzodiazepines in the treatment of mental disorders: The case against (invited debate)." European Psychiatry 26, S2 (2011): 1793. http://dx.doi.org/10.1016/s0924-9338(11)73497-6.

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Benzodiazepines have anxiolytic, hypnotic, muscle-relaxant and anticonvulsant properties. They also lessen agitation in the psychotic patient. They are much safer than previously available drugs such as the barbiturates. All sedative drugs have characteristic pharmacodynamic effects, causing sedation, psychomotor slowing and memory impairment.The widespread use of benzodiazepines long-term is problematic. Even though some tolerance develops, long-term users are impaired in cognitive and psychomotor function compared to non-users. Tapering the drugs, even after several years of use, results in
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Lader, M. "DB03-02 - We still need benzodiazepines in the treatment of mental disorders: The case against (invited debate)." European Psychiatry 26, S2 (2011): 1794. http://dx.doi.org/10.1016/s0924-9338(11)73498-8.

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Benzodiazepines have anxiolytic, hypnotic, muscle-relaxant and anticonvulsant properties. They also lessen agitation in the psychotic patient. They are much safer than previously available drugs such as the barbiturates. All sedative drugs have characteristic pharmacodynamic effects, causing sedation, psychomotor slowing and memory impairment.The widespread use of benzodiazepines long-term is problematic. Even though some tolerance develops, long-term users are impaired in cognitive and psychomotor function compared to non-users. Tapering the drugs, even after several years of use, results in
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Books on the topic "Sedative drugs namely benzodiazepines"

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Williams, Arthur Robin, and Olivera J. Bogunovic. Benzodiazepines and Other Sedative-Hypnotics in the Older Adult. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199392063.003.0007.

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Sedative-hypnotic-use disorder is a serious problem in the elderly and is a growing concern in the United States. The American Geriatrics Society’s “Choosing Wisely” initiative cautions against the use of any benzodiazepines or other sedative-hypnotics as initial treatment in older adults, yet benzodiazepines are the most frequently prescribed drugs in the elderly for both insomnia and anxiety. Other classes of medication (e.g., serotoninergic antidepressants) may be substituted for benzodiazepines based on diagnosis. With advancing age, the elderly are more sensitive to the potential side eff
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Book chapters on the topic "Sedative drugs namely benzodiazepines"

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"Benzodiazepines and other sedative-hypnotics." In Oxford Handbook of Addiction Medicine, 3rd ed., edited by John B. Saunders, David J. Nutt, Susumu Higuchi, et al. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/med/9780192844088.003.0014.

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Abstract Chapter 14 of Addiction Medicine covers the range of sedative-hypnotic drugs, principally the benzodiazepines but also the barbiturates and ‘z’ drugs. The clinical indications for these drugs are fewer nowadays, given the concern about their abuse and dependence risks but up to 10% of adults take them. Guidelines on their (more limited) indications in modern medical practice are outlined. The chapter covers the pharmacology of different benzodiazepines and ‘z’ drugs, with information on half-lives and dosage equivalents. The clinical features of overdose, dependence (addiction), and w
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Winger, Gail, James H. Woods, and Frederick G. Hofmann. "Depressants of the Central Nervous System: Alcohol, Barbiturates, and Benzodiazepines." In A Handbook on Drug and Alcohol Abuse. Oxford University PressNew York, NY, 2004. http://dx.doi.org/10.1093/oso/9780195172782.003.0004.

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Abstract Alcohol, barbiturate and nonbarbiturate sedative-hypnotic drugs, and the benzodiazepine minor tranquilizers are a chemically heterogeneous collection of compounds that have a great deal of pharmacology in common. Their profiles of action include disinhibition of behavior and reduction of anxiety following ingestion of small doses, sedation and ataxia following administration of intermediate doses, and anesthesia and coma after taking larger doses. Alcohol, primarily because it lacks potency (relatively large doses are required to produce these effects), has no clinical application as
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Barnett, Shannon R., and Mark A. Riddle. "Anxiolytics: benzodiazepines, buspirone, and others." In Pediatric Psychopharmacology: Principles and Practice. Oxford University PressNew York, NY, 2002. http://dx.doi.org/10.1093/oso/9780195141733.003.0027.

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Abstract In the treatment of children and adolescents with anxiety disorders clinicians have a wide variety of pharmacologic options beyond the antidepressants (Shader and Greenblatt, 1995; Lydiard et al., 1996; Riddle et al., 1999). The benzodiazepines (BZs), with their favorable safety profile and quick onset of action, are attractive alternatives for the treatment of acute anxiety. While the clinical effectiveness of buspirone has not been proven in children, buspirone is used alone or in combination with other drugs in the treatment of anxiety disorders. The antihistamines are often used t
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Meechan, John G., Nigel D. Robb, and Robin A. Seymour. "The pharmacology of sedative agents." In Pain and anxiety control for the conscious dental patient. Oxford University PressNew York, NY, 1998. http://dx.doi.org/10.1093/oso/9780192628497.003.0014.

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Abstract This chapter will consider the pharmacology of the commonly used sedative agents, particularly the benzodiazepines and nitrous oxide. Newer inhalation agents which have been used for sedation and propofol, an intravenous anaes thetic agent will also be discussed. Pharmacology can be considered as having two components, pharmacody namics and pharmacokinetics. Pharmacodynamics can be defined as the effect that drugs have on the patient, while pharmacokinetics can be defined as the effect that the patient has on the drug. Pharmacodynamics considers both the therapeutic and the unwanted o
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Winter, Jerrold. "Depressants: Sedative-Hypnotic-Tranquilizing Drugs—From Errant Yeast to Halcion and Its Relatives." In Our Love Affair with Drugs. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190051464.003.0009.

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The agents we will consider in this chapter are a disparate bunch, but they are united in that most can induce a mild state of intoxication that many of us find to be pleasant; social drinkers of ethyl alcohol are familiar with the phenomenon. The darker side of these drugs is that all can induce physical dependence with a characteristic and sometimes life-threatening withdrawal syndrome. In addition, they are often agents of addiction; alcoholism is a prime example. Further uniting these drugs is the relatively recent recognition of a common mechanism of action. Their current primary medical
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Koob, George F. "Drug Withdrawal." In The Benzodiazepines Crisis. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780197517277.003.0007.

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Drug withdrawal has long been considered a key symptom in the diagnosis of alcohol and substance use disorders. In this chapter, it is also conceptualized as a major motivational factor that drives compulsive drug taking. Drawing from the negative emotional components of withdrawal, termed hyperkatifeia (i.e., the negative emotional and motivational signs of withdrawal), the hypothesis here is that withdrawal sets up another major source of reinforcement—namely, negative reinforcement—for drug seeking in substance use disorders. From the perspective of the hyperkatifeia phenotype, withdrawal t
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FERNANDA SOUSA, MARIA, LUDMILA SERRÃO LOBATO, MARIA ANTONIA LEONARDO PEREIRA NETA, ANTÔNIO FABRÍCIO ALVES FERREIRA, and NEURINÉIA MARGARIDA ALVES DE OLIVEIRA GALDEZ. "SEDAÇÃO MÍNIMA EM ODONTOPEDIATRIA: EMPREGO DE BENZODIAZEPÍNICOS E N2 O/O2." In ESTUDOS MULTIDISCIPLINARES SOBRE SAÚDE DA CRIANÇA E DO ADOLESCENTE. Editora Academic, 2023. http://dx.doi.org/10.58871/ed.academic.00029.v2.

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Objective: The objective of this review is presented as advantages of the use of benzodiazepines and N2 O/O2 in the minimal sedation of the child patient during dental care. Methodology: The present work, through a background review of a narrative character elaborated through the search for articles in Portuguese and that were available in the PubMed, Google Scholar and English Scielo databases, included articles and works published between 2011 and 2021. Results and Discussion: The literature shows that benzodiazepines are the drugs as an alternative to control fear and anxiety in the dental
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"Pharmacology and mechanisms of addiction." In Oxford Handbook of Addiction Medicine, 3rd ed., edited by John B. Saunders, David J. Nutt, Susumu Higuchi, et al. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/med/9780192844088.003.0004.

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Abstract Chapter 4 of Addiction Medicine outlines the pharmacology of the most commonly used psychoactive substances, including their pharmacokinetics and pharmacodynamics. The chapter encompasses the pharmacology of alcohol, sedative-hypnotics (including benzodiazepines and ‘z’ drugs), opioids, amphetamine-type substances, cocaine, caffeine, nicotine, hallucinogens (such as LSD and psilocybin), empathogens, inhalants, and anabolic steroids. Psychoactive substances with dependence-inducing (addictive) potential have certain characteristics which distinguish them from other substances. These an
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Jowza, Maryam, and Dominika James. "Epilepsy." In Advanced Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197584521.003.0058.

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Abstract Seizures are among the most common neurological disorders encountered by anesthesiologists. Prevention and treatment of perioperative seizure is of utmost importance during neurosurgical procedures as uncontrolled seizures increase brain tissue metabolic demand and lead to poor operative outcomes. Perioperative use of antiepileptic drugs (AEDs) effectively decreases risk of intraoperative seizure events. AEDs, although very effective, are associated with many adverse effects and can interact with anesthetic agents. Phenytoin, phenobarbital, and carbamazepine induce hepatic microsomal
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Ramesh, Bhagyalakshmi. "Uses of Ketamine in the Paediatric Population." In Ketamine Revisited - New Insights into NMDA Inhibitors [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103658.

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General anesthesia in pediatric patients can vary from light sedation to complete anesthesia with unconsciousness, amnesia and muscle relaxation. A wide variety of procedures are done under general anesthesia in children ranging from surgeries done for correction of congenital defects, cardiac surgeries, scoliosis surgery, hernia surgery etc. to procedures done outside the operating room (OR) for diagnostic and therapeutic purposes. Non-Operating room Anesthesia (NORA) may include painless procedures like CT scan, MRI, radiotherapy for cancer treatment etc. or painful procedures like biopsy, l
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