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Journal articles on the topic 'Segment opacities'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Eppley, Sarah E., Neel D. Pasricha, Gerami D. Seitzman, Ashlin Joye, Alejandro Arboleda, and Azam Qureshi. "Multimodal Imaging of Posterior Corneal Opacities in Multicentric Osteolysis Nodulosis and Arthropathy." Cornea Open 3, no. 3 (2024): e0044. http://dx.doi.org/10.1097/coa.0000000000000044.

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Purpose: Multicentric osteolysis nodulosis and arthropathy (MONA) syndrome is a rare autosomal recessive skeletal dysplasia. Caused by mutations in the matrix metalloproteinase 2 (MMP2) gene on chromosome 16q12, this syndrome has infrequently been associated with ophthalmic manifestations. Corneal opacities have been reported but not described or documented in detail. Methods: Complete ophthalmologic examination and multimodal anterior segment imaging were used to characterize the corneal findings in a patient with MONA syndrome. Results: A 19-year-old man with MONA syndrome was referred for a

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Mok, Eugenie, Ka Wai Kam, Anthony J. Aldave, and Alvin L. Young. "Diagnosing Paraproteinemic Keratopathy: A Case Report." Case Reports in Ophthalmology 12, no. 2 (2021): 337–43. http://dx.doi.org/10.1159/000514375.

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A 65-year-old man presented with bilateral, painless, progressive blurring of vision over 9 years. Slit-lamp examination revealed bilateral subepithelial corneal opacities in clusters located at the mid-periphery. Anterior segment optical coherence tomography, in vivo confocal microscopy (IVCM), serum protein electrophoresis, and molecular genetic testing were performed to evaluate the cause of corneal opacities. Anterior segment optical coherence tomography revealed a band-like, hyperreflective lesion in the Bowman layer and anterior stroma of both corneas. IVCM revealed hyperreflective depos

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Majander, Anna S., Päivi M. Lindahl, L. Kristiina Vasara, and Kari Krootila. "Anterior Segment Optical Coherence Tomography in Congenital Corneal Opacities." Ophthalmology 119, no. 12 (2012): 2450–57. http://dx.doi.org/10.1016/j.ophtha.2012.06.050.

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Pleskova, A. V. "Nosological Corneal opacities structure in children: background." Russian Pediatric Ophthalmology 9, no. 2 (2014): 39–43. https://doi.org/10.17816/rpoj37585.

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This paper presents the structure and diseases of the cornea pathology leading to childhood blindness and visual impairment in different regions of the world. Epidemiology of corneal opacities in children examined in historical perspective, taking into account the socio-economic development of society. In economically developed European countries and America, the main cause of corneal opacities in children are congenital malformations of the eye anterior segment, in developing countries, the leading cause of corneal blindness occupy inflammatory corneal opacity (due to previous infectious kera

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Shigeyasu, Chika, Masakazu Yamada, Yoshinobu Mizuno, Tadashi Yokoi, Sachiko Nishina, and Noriyuki Azuma. "Clinical Features of Anterior Segment Dysgenesis Associated With Congenital Corneal Opacities." Cornea 31, no. 3 (2012): 293–98. http://dx.doi.org/10.1097/ico.0b013e31820cd2ab.

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Wong, A. L., C. K.-S. Leung, R. N. Weinreb, et al. "Quantitative assessment of lens opacities with anterior segment optical coherence tomography." British Journal of Ophthalmology 93, no. 1 (2008): 61–65. http://dx.doi.org/10.1136/bjo.2008.137653.

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Couto, Cristóbal, Erika Hurtado, Dana Faingold, et al. "Atypical Bilateral Fuchs Uveitis: Diagnostic Challenges." Case Reports in Ophthalmology 6, no. 3 (2015): 284–88. http://dx.doi.org/10.1159/000439081.

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Bilateral Fuchs uveitis associated with vitreous infiltration and posterior segment involvement requires a thorough diagnostic evaluation. The lack of well-defined diagnostic criteria makes identification of this entity difficult. The aim of this case report was to present the characteristics of a patient with atypical Fuchs uveitis and the procedures needed to rule out the differential diagnosis with specific attention to the utility of in vivo confocal microscopy (IVCM). Case Report: One case of chronic bilateral uveitis with severe vitreous opacities is presented. After extensive systemic w

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Chentsova, E. V., and A. V. Rakova. "Femtosecond laser-assisted anterior lamellar keratoplasty in patients with corneal opacities." Russian Pediatric Ophthalmology 9, no. 2 (2014): 32–35. https://doi.org/10.17816/rpoj37573.

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The purpose of the study was to explore the possibilities of femtosecond laser-assisted anterior lamellar keratoplasty in patients with corneal opacities of various etiology. Materials and Methods. Femtosecond laser-assisted anterior lamellar keratoplasty (FALK) performed in 8 patients (4 males, 4 females) with superficial corneal opacities at the age from 16 to 20 years. Etiology of corneal opacities: in 3 cases - keratitis of unknown etiology, 2 - herpetic keratitis, 2 - burns, 1 - ulcer. Examination technics: visometry, autorefractometry, biomicroscopy, ophthalmoscopy, tonometry, ultrasonic

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Basdekidou, Chrysanthi, Pascal Dureau, Catherine Edelson, Patrice De Laage De Meux, and Georges Caputo. "Should Unilateral Congenital Corneal Opacities in Peters’ Anomaly be Grafted?" European Journal of Ophthalmology 21, no. 6 (2011): 695–99. http://dx.doi.org/10.5301/ejo.2011.6317.

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Purpose. To evaluate the surgical outcomes and visual results after penetrating keratoplasty for congenital unilateral corneal opacities in Peters anomaly. Methods. This was a retrospective study of 14 children who underwent keratoplasty for a unilateral Peters anomaly between 1999 and 2009. All patients received a topical treatment of cyclosporine and corticosteroids. Suture ablation was performed between the first and second postoperative month and all patients had spectacle correction and amblyopia treatment. Age at time of surgery, posterior segment status evaluated by ultrasonography, axi

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Sofia, Soccorsa, Giacomo Filonzi, Leonardo Catalano, et al. "A New HRCT Score for Diagnosing SARS-CoV-2 Pneumonia: A Single-Center Study with 1153 Suspected COVID-19 Patients in the Emergency Department." International Journal of Translational Medicine 3, no. 4 (2023): 399–415. http://dx.doi.org/10.3390/ijtm3040028.

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The 2019 coronavirus disease (COVID-19) pandemic is affecting millions of people worldwide. Chest high-resolution computed tomography (HRCT) is commonly used as a diagnostic test for suspected COVID-19; however, despite numerous attempts, there is no single scoring system that is widely accepted and used in clinical practice to estimate the probability of SARS-CoV-2 pneumonia. The aim of this single-center retrospective study is to develop a radiological score to predict the probability of COVID-19 with HRCT. Patients admitted to the emergency department with symptoms suggestive of COVID-19 wh

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Hariharan, Luxme, Dilshad Contractor, Julia Johnston, Tova Mannis, and Bibiana Jin Reiser. "Using anterior segment imaging as a guide for the surgical management of pediatric corneal opacities." Journal of American Association for Pediatric Ophthalmology and Strabismus 19, no. 4 (2015): e46. http://dx.doi.org/10.1016/j.jaapos.2015.07.139.

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Sheth, Hiten G., Patricio Pacheco, Ahmed Sallam, and Sue Lightman. "Pole to Pole Intraocular Transit of Tarantula Hairs—An Intriguing Cause of Red Eye." Case Reports in Medicine 2009 (2009): 1–2. http://dx.doi.org/10.1155/2009/159097.

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This intriguing case report provides novel images and a description of the anterior and rarer posterior segment findings seen in ocular inflammation associated with tarantula spider hair exposure. We present an interventional case report of a 9-year-old boy who presented with a red, sore eye. Slit lamp examination revealed right eye injection, multiple small hairs at differing levels of the cornea with associated opacities and inflammation within the anterior and posterior segments of the eye. Only after detailed and repeated questioning did the aetiology become apparent. Conservative manageme

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Afzal, Sidra. "Assessment of COVID-19 Severity Using Chest CT Severity Score on High-Resolution Computed Tomography Chest in Pakistani Patients." Pakistan Journal of Medical and Health Sciences 16, no. 5 (2022): 721–23. http://dx.doi.org/10.53350/pjmhs22165721.

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Objective: The current review aims at portraying the high-resolution CT (HRCT) chest findings of corona virus pandemic that emerged in 2019 amongst the COVID-19 patients, admitted to the tertiary healthcare facilities in Punjab, Pakistan. It also aims to study the imaging features and dispensation of COVID-19 infection in different segments of the lungs. Moreover, a survey was also conducted for the job to analyze the chest CT severity score index (CT-SS) aims at identifying those patients with acute infections. Methods: This cross-sectional descriptive analysis led from May 15, 2020 to Novemb

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Elalfy, Mohamed, Sundas Maqsood, Aja Reinhold, et al. "Clinical outcomes after intracorneal ring segment implantation for keratoconus management in corneas with mild apical haze." Therapeutic Advances in Ophthalmology 13 (January 2021): 251584142110033. http://dx.doi.org/10.1177/25158414211003378.

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Purpose:The implantation of intracorneal ring segments represents an effective and safe therapeutic option for visual improvement in patients with keratoconus. The presence of corneal opacities is considered an exclusion criterion for this operation.Methods:This is a retrospective cohort study of six eyes of six keratoconus patients at Queen Victoria Hospital, East Grinstead, UK, between January 2012 and December 2016. Femtosecond laser-assisted intracorneal ring segment implantation was performed in six eyes with apical corneal haze. Preoperative and postoperative visual acuity, keratometry r

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Kaginalkar, Ananya, Radhika Tandon, M. Vanathi, et al. "Clinical and diagnostic imaging profile of three anterior segment dysgenesis disorders presenting with infantile corneal opacities." Taiwan Journal of Ophthalmology 13, no. 4 (2023): 505–19. http://dx.doi.org/10.4103/tjo.tjo-d-23-00134.

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PURPOSE: To describe three anterior segment dysgenesis disorders with infantile corneal opacities, namely, congenital hereditary endothelial dystrophy (CHED), primary congenital glaucoma (PCG), and Peters anomaly (PA) in terms of clinical characteristics, histopathology, genetic association, and diagnostic imaging profiles using imaging modalities such as ultrasound biomicroscopy (UBM) and microscope-integrated intraoperative optical coherence tomography (i-OCT). MATERIALS AND METHODS: Seventy-four eyes with 22 eyes of CHED, 28 eyes of PA, and 24 eyes of PCG were clinically evaluated and under

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Saiju, R., S. Yun, PD Yoon, MK Shrestha, and UD Shrestha. "Bruckner Red Light Reflex Test in a Hospital Setting." Kathmandu University Medical Journal 10, no. 2 (2013): 23–26. http://dx.doi.org/10.3126/kumj.v10i2.7338.

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Background Childhood blindness is a major problem in developing world including Nepal that needs to be addressed. Objective The objective of study was to measure the effectiveness of the Bruckner red reflex test for screening of posterior segment opacities in children. Methods Patients aged less than five years who came to the Tilganga Institute of Ophthalmology, Kathmandu from March to August, 2009 were recruited in this cross-sectional descriptive study. Children were screened with the Bruckner red light reflex test in a dark room. Patients with abnormal Bruckner tests had their eyes dilated

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Alimanović Halilović, Emina. "Correlation Between Eye Aperture Diameter and Complications in the Posterior Eye Segment after Nd-Yag Capsulotomy." Bosnian Journal of Basic Medical Sciences 8, no. 2 (2008): 106–9. http://dx.doi.org/10.17305/bjbms.2008.2961.

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The aim of our research was to explore possible correlation between eye aperture diameter and occurrence of complications in the posterior eye segment after Nd-YAG capsulotomy. In the study, we analyzed 120 eyes of the patients who experienced opacities in the posterior capsule or developed secondary cataract after the surgery. All patients underwent Nd-YAG laser posterior capsulotomy. Thereafter, we monitored complications occurrence in the posterior eye segment in intervals of one hour, seven days, one month and six months following the surgery. The frequency of complications increased with

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Kannan, Balaji. "Keratoconus associated with cone-rod dystrophy." Asian Journal of Ophthalmology 14, no. 3 (2015): 115–17. http://dx.doi.org/10.35119/asjoo.v14i3.128.

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Keratoconus is known to be associated with a variety of ocular and systemic disorders. The common posterior segment disorders known to be associated with keratoconus are retinitis pigmentosa, macular coloboma, Leber’s congenital amaurosis, retinal aplasia and retrolental fibroplasias. Occurrences of keratoconus in association with tapetoretinal degeneration is rare and has been reported infrequently. Visualization of the fundus is often difficult in cases of keratoconus due to the associated refractive error and corneal opacities. This may make it difficult for the ophthalmologist to clinicall

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Kim, Woojin, Sumin Yoon, Dong Hyun Kim, Youngsub Eom, and Jong Suk Song. "Differences between the Results Assessed by Slit Lamp Examination and Anterior Segment Photography in Terms of Cataract Grading." Journal of the Korean Ophthalmological Society 64, no. 11 (2023): 1009–13. http://dx.doi.org/10.3341/jkos.2023.64.11.1009.

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Purpose: We compared the cataract grades with slit lamp examination and anterior segment photography using the Lens Opacities Classification System (LOCS) III criteria. We also explored the effect of a yellow filter on the photographic results.Methods: Eighty eyes with cataracts were examined by three inspectors (1, 2, and 3). Anterior segment photographs taken by inspector 1 were divided into two groups depending on whether cortical opacity or nuclear sclerosis predominated. In each group, the cataract grades determined by inspector 1 on slit lamp examination and anterior segment photography

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Mohcine, El Mhadi, El Ouafi Aziz, Boughanim Meryem, and Iferkhass Said. "Schnyder Crystalline Corneal Dystrophy: A Case Report." SAS Journal of Medicine 8, no. 2 (2022): 54–57. http://dx.doi.org/10.36347/sasjm.2022.v08i02.001.

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Schnyder crystalline corneal dystrophy (SCCD) is a rare hereditary corneal pathology, the clinical forms of which can be varied. It is classically characterized by the presence of central corneal disc or ring opacities, with or without the presence of crystals, and sometimes the association with a peripheral corneal arch or the limbic belt of Vogt. Its pathogenesis is linked to an abnormality in lipid metabolism with accumulation of lipids (phospholipids or cholesterol) in the cornea. We report the case of a 30-year-old patient, with no particular history, presenting a progressive decrease in

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Chen, Wen-Si, Dao-Man Xiang, and Lan-Xiang Hu. "Ultrasound Biomicroscopy Detects Peters’ Anomaly and Rieger’s Anomaly in Infants." Journal of Ophthalmology 2020 (March 23, 2020): 1–10. http://dx.doi.org/10.1155/2020/8346981.

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Aim. Congenital corneal opacities (CCOs) are the major causes of early visual deprivation in infants. Balloon ultrasound biomicroscopy (UBM) examination is an effective method to diagnose CCO. However, whether it is suitable for children examination is still unknown. Methods. 26 Peters’ anomaly (PA) or Rieger’s anomaly (RA) infants with congenital corneal opacities (CCO) (40 eyes) underwent UBM examinations to study their imaging features. Results. Based on the results, they were divided into UBM Dx-Type I: Descemet’s membrane (DM) and endothelium have heterogenous or discontinuous echo accomp

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Kim, You Na, Jin Hyoung Park, and Hungwon Tchah. "Quantitative Analysis of Lens Nuclear Density Using Optical Coherence Tomography (OCT) with a Liquid Optics Interface: Correlation between OCT Images and LOCS III Grading." Journal of Ophthalmology 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/3025413.

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Purpose. To quantify whole lens and nuclear lens densities using anterior-segment optical coherence tomography (OCT) with a liquid optics interface and evaluate their correlation with Lens Opacities Classification System III (LOCS III) lens grading and corrected distance visual acuity (BCVA).Methods. OCT images of the whole lens and lens nucleus of eyes with age-related nuclear cataract were analyzed using ImageJ software. The lens grade and nuclear density were represented in pixel intensity units (PIU) and correlations between PIU, BCVA, and LOCS III were assessed.Results. Forty-seven eyes w

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Akoğlu, Handan A., Muhammet Bulut, Dilek K. Alemdar, et al. "Evaluation of Childhood COVID-19 Cases: A Retrospective Analysis." Journal of Pediatric Infectious Diseases 16, no. 03 (2021): 091–98. http://dx.doi.org/10.1055/s-0041-1723957.

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Abstract Objective This study aims to evaluate the demographic, epidemiological, and clinical features of novel coronavirus disease 2019 (COVID-19) cases aged between 0 and 18 years. Methods The demographic characteristics of the patients, admission symptoms, contact and travel histories, clinical onset duration, symptoms, treatments, laboratory findings, radiological images, and polymerase chain reaction (PCR) negation times were evaluated in a retrospective manner. Thirty-eight children (19 boys and 19 girls) were included in the study. Results The mean age of the patients was 10.36 ± 5.59 y

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M., Santha, Sridhar Goli, Prasad Killani Srinivas, and Obaidullah Khan Mohammed. "A Study of Clinical Outcomes of Pediatric Penetrating Keratoplasty at a Tertiary Eye Care Center." International Journal of Pharmaceutical and Clinical Research 16, no. 9 (2024): 163–68. https://doi.org/10.5281/zenodo.13886741.

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<strong>Background: </strong>Penetrating keratoplasty in children is a complex and demanding procedure, often carrying a high risk of graft failure or unsuccessful amblyopia treatment, even in cases with clear grafts. Despite these challenges, keratoplasty remains the preferred surgical option for managing pediatric corneal stromal opacities or edema. The current study was done to determine the indications and clinical outcomes of pediatric penetrating keratoplasty. <strong>Methods: </strong>This prospective study was conducted in the Department of Ophthalmology,  Sarojini

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Safonova, O. V., O. Shilovskikh, and V. N. Kazaikin. "Surgical Treatment of Cataracts Complicated by Chronic Uveitis. Literature Review." Ophthalmology in Russia 21, no. 2 (2024): 238–47. http://dx.doi.org/10.18008/1816-5095-2024-2-238-247.

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The problem of surgical treatment of cataracts in patients with chronic uveitis is relevant due to a high proportion of intra and postoperative complications, despite the development of modern microinvasive technologies. Associated complications of chronic uveitis (adhesions in the anterior eye segment, secondary glaucoma, vitreous opacities, cystoid macular edema, etc.), difficulties in intraocular lens implantation, the need for pharmacological support and subsequent rehabilitation of patients complicate surgery, while many issues remain controversial. Late patients’ recourse for medical ai

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Nayak, Dhruvil V., Harish Trivedi, and Prapti Rathod. "Occular manifestation of a case of lamellar ichthyosis." IP International Journal of Ocular Oncology and Oculoplasty 9, no. 1 (2023): 39–41. http://dx.doi.org/10.18231/j.ijooo.2023.008.

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A baby full term born of LSCS to a otherwise healthy mother was referred for ophthalmology department. On ophthalmological torch light examination, the patient had equal upper and lower lid bilateral ectropion. There was missing eye lashes noted. The anterior segment evaluation was found to be within normal limit without evidence of corneal opacities. Lamellar ichthyosis otherwise termed as Collodion baby is a infrequent disease; and there is no well-known management protocol. The Patient was managed conservatively by the use of Hydroxy propyl methyl cellulose (2% w/v) eye ointment and lubrica

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Mackenbrock, Lars H. B., Grzegorz Łabuz, Timur M. Yildirim, Gerd U. Auffarth, and Ramin Khoramnia. "Automatic Quantitative Assessment of Lens Opacities Using Two Anterior Segment Imaging Techniques: Correlation with Functional and Surgical Metrics." Diagnostics 12, no. 10 (2022): 2406. http://dx.doi.org/10.3390/diagnostics12102406.

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The purpose of this study is to quantitatively assess lens opacity, using a swept-source optical coherence tomography (SS-OCT) device for anterior segment assessment, and establish the correlation with Scheimpflug imaging, corrected distance visual acuity (CDVA) and cumulative dissipated energy (CDE). This prospective cross-sectional single-center study enrolled 51 patients (51 eyes) with crystalline lens opacity. Patients with previous ocular surgery, pathologies or general disorders affecting vision were excluded. Eyes were scanned with an SS-OCT device, and lens densitometry was automatical

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Tereshchenko, A. V., I. G. Trifanenkova, and E. V. Yerokhina. "Features of the Anterior Segment of the Eyeball in Children with 5 Cicatricial Retinopathy of Prematurity According to Ultrasound Biomicroscopy and Optical Coherent Tomography." Ophthalmology in Russia 17, no. 3 (2020): 451–58. http://dx.doi.org/10.18008/1816-5095-2020-3-451-458.

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Purpose: to study the features of the anatomical and topographic relationships of the eye’s anterior segment structures in children with stage 5 ROP in the cicatricial period with the method of ultrasound biomicroscopy and optical coherent tomography of the anterior segment and to evaluate the possibility of using the data to optimize the surgical treatment of ROP.Patients and methods. For the period 2015–2018 in the Kaluga branch of the Fyodorov Eye Microsurgery, 68 children (118 eyes) with 5 cicatricial ROP stages were examined and treated. Gestational age at birth varied from 24 to 31 weeks

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Tulin, D. V., A. R. Kuznetsov, N. N. Nevin, A. A. Dzilikhov, and T. Y. Bogdanova. "Experience in using optical coherence tomography for monitoring of the anterior segment structures following staged surgical treatment of combat-related eye injuries." Modern technologies in ophtalmology 58, no. 6 (2024): 109–13. https://doi.org/10.25276/2312-4911-2024-6-109-113.

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Relevance: Combat-related eye injuries often pose significant diagnostic challenges, particularly when corneal opacities hinder traditional assessment methods like biomicroscopy. Optical coherence tomography (OCT) enables high-resolution imaging of anterior segment structures, providing critical insights for accurate diagnosis and post-surgical monitoring in such cases. Objective: To evaluate the effectiveness of anterior segment OCT in monitoring structural changes in the anterior chamber following staged surgical interventions in patients with combat-related eye injuries. Materials and Metho

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Evdulov, O. V., G. I. Aminov, I. Yu Aminova, I. G. Aminov, and G. A. Mutalipova. "Thermoelectric device for transpalpebral hypothermia of the anterior segment of the human eyeball." Herald of Dagestan State Technical University. Technical Sciences 51, no. 1 (2024): 14–21. http://dx.doi.org/10.21822/2073-6185-2024-51-1-14-21.

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Objective. The purpose of the study is to develop the design of a thermoelectric device for transpalpebral hypothermia of the anterior segment of the human eyeball.Method. The design of a TEU for thermal impact on the anterior segment of the human eyeball is described. The device includes an impact tip mated with one surface to the human eyelid, and the opposite surface to the cold surface of the thermo-electric module. The hot surface is in contact with a housing filled with a working substance having a stable melting point ranging from 303 to 330 K. The device is equipped with an adjustable

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Yulia, Dian E., Julie D. Barliana, and Laureen Celcilia. "Complex pediatric cataract surgery in the presence of anterior segment dysgenesis: A case report." Indian Journal of Ophthalmology - Case Reports 5, no. 1 (2025): 8–11. https://doi.org/10.4103/ijo.ijo_2152_24.

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Congenital cataract is the most common cause of treatable childhood blindness worldwide, and it may coexist with other ocular abnormalities such as corneal opacities and iris deformities. This case report presents the challenging management of congenital cataracts associated with anterior segment dysgenesis (ASD) in a 5-year-old male patient. The patient presented with bilateral corneal adherent leukomas, iridocorneal synechiae, and cataracts, which resulted in severe visual impairment. The best-corrected visual acuity was 3/60 in the left eye (LE) and 0.5/60 in the right eye (RE). Cataract ex

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Dhungana, AP. "Ocular morbidity in hearing impaired school children in Eastern Nepal." Journal of Kathmandu Medical College 3, no. 1 (2014): 4–7. http://dx.doi.org/10.3126/jkmc.v3i1.10916.

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Background: The association between deafness and ocular problems is well established; however the nature and prevalence of these problems are diverse across the globe. Objective: The aim of this study is to determine the nature and prevalence of ophthalmologic abnormalities in deaf students and offer treatment to those with remediable conditions. Method: Eighty seven deaf students aged between six and 25 years were examined in a school for the deaf. The study was cross-sectional and descriptive in nature. The research proforma was developed to collect the data. Data were analyzed using Microso

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Israel, Mervin Jonathan, and Keerti Wali. "Schnyders corneal dystrophy: A case report." Indian Journal of Clinical and Experimental Ophthalmology 9, no. 4 (2023): 650–52. http://dx.doi.org/10.18231/j.ijceo.2023.122.

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Schnyder corneal dystrophy (SCD) is a rare, autosomal dominant inherited dystrophy affecting the anterior stroma of the cornea. It is caused by a local metabolic defect mapped on the UBIAD1 gene chromosome 1p36. It is known to causes progressive bilateral opacification of the cornea due to an abnormal accumulation of phospholipids and cholesterol in the cornea. In our case a 22-year-old male with vision loss and ocular discomfort revelled multiple grey, infiltrates or disc like opacities in both eyes arranged in circinate manner on slit-lamp, involving the sub-epithelium and stroma. On anterio

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Ivanova, Gordana, and Emilija Gjosevska Dastevska. "The Role of Standardized Echography in Preoperative Preparations of Patients with Senile Cataract." Macedonian Medical Review 70, no. 1 (2016): 8–11. http://dx.doi.org/10.1515/mmr-2016-0002.

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Abstract Introduction. The standardized echography is a non-invasive, simple, efficient and painless diagnostic method, which allows visualization and evaluation of posterior eye segment through non-transparent media, such as blurring lens or cataract. The aim of the study was to emphasize the role and importance of standardized echography in preoperative preparation of patients and evaluation of posterior eye segment in patients with senile cataracts. Methods. During a 6 month-period, from 05.05.2015 to 11.05.2015, a total of 718 ultrasound examinations were made in patients with previously d

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Hu, Shi-Si, Xu-Yun Meng, Bo-Wen Ouyang, Zhen-Duo Yang, Xiao-Dan Chen, and Xing-Wu Zhong. "Treatment of superficial corneal opacities with corneal stromal lenticule obtained through SMILE surgery." International Journal of Ophthalmology 17, no. 12 (2024): 2221–28. http://dx.doi.org/10.18240/ijo.2024.12.09.

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AIM: To evaluate the clinical efficacy and feasibility of superficial corneal opacities treated by excimer laser phototherapeutic keratectomy (PTK) combined with small incision lenticule extraction (SMILE)-derived corneal stromal lenticule transplantation. METHODS: A retrospective interventional case series of nine patients aged 12–59y with superficial corneal opacity caused by different pathologies who underwent standardized PTK combined with SMILE-derived corneal stromal lenticule transplantation was examined. Lenticule patches were fixed with fibrin glue. All patients underwent pre- and pos

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Patil, Dr Shital, Jayashree Dahiphale, Vipul Raka, Sanika Narkar, Shubham Choudhari, and Gajanan Gondhali. "‘Stepladder Lung Cavities’ with ‘Starry Sky Pattern’ in HRCT Thorax with Constitutional Symptoms: A Strong Predictor of Active Pulmonary Tuberculosis." SAR Journal of Medicine 4, no. 02 (2023): 32–42. http://dx.doi.org/10.36346/sarjm.2023.v04i02.003.

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Pulmonary Tuberculosis is most common diseases in India with significant mortality and morbidity. Tuberculosis can cause diverse thoracic presentations ranging from nodules, consolidations & cavitation, mediastinal adenopathy, pleural effusion to diffuse endobronchial disease presenting like bronchial asthma. In this case report, 29- year male, presented with constitutional symptoms for 4 months duration with partial response to medical treatment received according to their knowledge and experience towards bronchial asthma, enteric fever and jaundice. Radiological investigations documented

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Lutsenko, N. S., O. A. Isakova, O. A. Rudycheva, and T. S. Kyrylova. "Assessment of the risk factors for the development and morphological types of posterior subcapsular cataract using optical coherence tomography." Zaporozhye Medical Journal 26, no. 3 (2024): 204–9. http://dx.doi.org/10.14739/2310-1210.2024.3.282503.

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Aim. To analyze the risk factors for the development of posterior subcapsular cataract in patients with different morphological changes using anterior segment optical coherence tomography. Materials and methods. A prospective clinical study on the risk factors for posterior subcapsular cataract was conducted during 2020–2022. The study involved 296 patients (512 eyes). The morphological type of the posterior capsule was evaluated using anterior segment optical coherence tomography (AS OCT), Optovue RTVue 100 XR Avanti (Optovue Inc., USA). Results. Significant differences have been found betwee

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D’ Elia, R., A. Pompa, M. Ciccarelli, C. Vecchione, and G. Galasso. "P319 MID VENTRICULAR TAKOTSUBO SYNDROME IN A PATIENT WITH COVID 19 PNEUMONIA: A CASE REPORT." European Heart Journal Supplements 25, Supplement_D (2023): D168. http://dx.doi.org/10.1093/eurheartjsupp/suad111.392.

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Abstract Background Takotsubo Syndrome (TTS) is an acute and transient myocardial disfunction associated with chest pain, electrocardiographic changes and minimal myocardial enzymatic release mimicking acute myocardial infarction but without significant coronary artery disease. Physical or emotional stress play a central role in the pathogenesisof this cardiomyopathy. Several variants have been described including the classic type, reverse Takotsubo, midventricular type and focal type. Mid ventricular Takotsubo is characterized by circumferential mid–ventricular hypokinesia with hypercontracti

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Maharramov, Polad M., and Fidan A. Aghayeva. "Evaluation of the effectiveness of combined staged surgical treatment in patients with keratoconus." PLOS ONE 17, no. 3 (2022): e0264030. http://dx.doi.org/10.1371/journal.pone.0264030.

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Purpose This study performs comparative assessment of the results of different types of two-stage surgical treatment in patients with keratoconus, including combination of corneal collagen cross-linking with intrastromal corneal ring segments followed by topography-guided photorefractive keratectomy. Materials and methods Prospective review of 101 patients (101 eyes) with keratoconus was performed. Patients underwent corneal collagen cross-linking (32 patients), intrastromal corneal ring segments (48 patients), and a combination of these two procedures (21 patients). Transepithelial topography

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Mounir, Amr, Emad Latif Matthias, and Islam Awny. "Two-year successful results of femto-LASIK in steep and opacified corneas." Medical Hypothesis, Discovery & Innovation in Optometry 1, no. 1 (2020): 37–43. http://dx.doi.org/10.51329/mehdioptometry106.

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 Background: Flap creation is the most critical step of laser in situ keratomileusis (LASIK). The introduction of the femtosecond laser with its uniform flaps, which enhance the accuracy of LASIK, has decreased the risk of flap-related complications like buttonholes and incomplete flaps. We recommended femtosecond laser-assisted LASIK (FS-LASIK) in the presence of superficial corneal opacities. Case Presentation: We report a case of a 31-year-old female who reported to the Cornea clinic of the Sohag Center for LASIK and Corneal Surgeries, Sohag, Egypt, complaining of bilateral decr

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Gonzalez-Gonzalez, Luis A., Colin J. Prensky, and Anton Orlin. "Delayed-Onset Propionibacterium acnes Endophthalmitis in the Absence of Capsular Complex Following Scleral-Fixated Intraocular Lens: A Case Report." Journal of VitreoRetinal Diseases 5, no. 5 (2021): 448–51. http://dx.doi.org/10.1177/2474126421989584.

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Purpose: This work reports a case of delayed-onset Propionibacterium acnes endophthalmitis in a patient with scleral-fixated intraocular lens (IOL), successfully treated with intravitreal antibiotics and steroids. Methods: Patient underwent complete ophthalmic examinations over 2 years. Vitreous cultures, optical coherence tomography, anterior segment and fundus photographs, and fluorescein angiogram were performed. Results: A 78-year-old man with dislocated IOL underwent IOL removal and scleral-fixated AO60. He did well for 2 months but returned 9 months later with vision loss. Examination re

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Giri, Puspa, Leena Bajracharya, and Sudha Ranabhat. "Macular Corneal Dystrophy in an Adolescent Managed with Deep Anterior Lamellar Keratoplasty." Nepalese Journal of Ophthalmology 14, no. 1 (2022): 204–7. http://dx.doi.org/10.3126/nepjoph.v14i1.39633.

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Introduction: Macular corneal dystrophy (MCD) is a rare autosomal recessive stromal dystrophy. The prevalence of inherited diseases varies in different communities. It is not commonly observed in Nepal. Case: A 14-year male presented with bilateral gradual and painless blurred vision with photophobia of three years duration. Cornea of both eyes showed focal grayish opacities in anterior and mid stroma with intervening stromal haze. There was no history of consanguinity in the family. Anterior segment ocular coherence tomography showed thinning of cornea and deposits in corneal stroma. Macular

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Nesi, Thiago Trindade, Daniel Amorim Leite, Fábio Medina Rocha, et al. "Indications of Optical Coherence Tomography in Keratoplasties: Literature Review." Journal of Ophthalmology 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/989063.

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Optical coherence tomography (OCT) of the anterior segment, in particular corneal OCT, has become a reliable tool for the cornea specialist, as it provides the acquisition of digital images at high resolution with a noncontact technology. In penetrating or lamellar keratoplasties, OCT can be used to assess central corneal thickness and pachymetry maps, as well as precise measurements of deep stromal opacities, thereby guiding the surgeon to choose the best treatment option. OCT has also been used to evaluate the keratoplasty postoperative period, for early identification of possible complicati

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Umapathy, Ankita, Paul Donaldson, and Julie Lim. "Antioxidant Delivery Pathways in the Anterior Eye." BioMed Research International 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/207250.

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Tissues in the anterior segment of the eye are particular vulnerable to oxidative stress. To minimise oxidative stress, ocular tissues utilise a range of antioxidant defence systems which include nonenzymatic and enzymatic antioxidants in combination with repair and chaperone systems. However, as we age our antioxidant defence systems are overwhelmed resulting in increased oxidative stress and damage to tissues of the eye and the onset of various ocular pathologies such as corneal opacities, lens cataracts, and glaucoma. While it is well established that nonenzymatic antioxidants such as ascor

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Ji, Yong Woo, Hyunmin Ahn, Kyoung-Jin Shin, et al. "De Novo L509P Mutation of the TGFBI Gene Associated with Slit-Lamp Findings of Lattice Corneal Dystrophy Type IIIA." Journal of Clinical Medicine 11, no. 11 (2022): 3055. http://dx.doi.org/10.3390/jcm11113055.

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Background: Mutations of the transforming growth factor-β-induced (TGFBI) gene produce various types of corneal dystrophy. Here, we report a novel de novo L509P mutation not located in a known hot spot of the transforming growth factor-β-induced (TGFBI) gene and its clinical phenotype, which resembles that of lattice corneal dystrophy type IIIA (LCD IIIA). Case presentation: A 36-year-old man (proband) visited our clinic due to decreased visual acuity with intermittent ocular irritation in conjunction with painful recurrent erosions in both eyes for 10 years. Molecular genetic analyses reveale

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Mandal, Sohini, Vaibhav Namdev, Seema Sen, and Rajesh Sinha. "Bilateral post-LASIK exacerbation of granular corneal dystrophy with epithelial ingrowth." BMJ Case Reports 16, no. 6 (2023): e254328. http://dx.doi.org/10.1136/bcr-2022-254328.

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A male patient in his 30s, with a history of bilateral microkeratome-assisted myopic laser-assisted in situ keratomileusis (LASIK) 8 years ago at another centre, presented to us with gradually progressive diminution of vision and glare in both eyes for the last 4 years. On presentation, uncorrected distance visual acuity (UDVA) was 6/24 and 6/15 in the right eye and left eye, respectively, with normal intraocular pressures. Slit-lamp examination and anterior segment optical coherence tomography revealed well-defined white deposits, limited to an area within the LASIK flap. The deposits were co

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Shrestha, Chunu, Sabina Shrestha, Aparajita Manoranjan, and Reeta Rajbhandari. "A 27 - Gauge Microincision Vitrectomy Surgery for Posterior Segment Diseases in a Tertiary Centre, Nepal." Medical Journal of Shree Birendra Hospital 20, no. 2 (2021): 91–96. http://dx.doi.org/10.3126/mjsbh.v20i2.30726.

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Introduction: Transconjunctival micro incision vitrectomy surgery (MIVS) with 23 or 25 gauge instrumentation is more advantageous than traditional 20 gauge surgery. We intended to evaluate the visual outcome, complications and indication of various vitreoretinal diseases using 27 Gauge vitrectomy systems.  Methods: This study was a prospective, interventional, non-comparative study conducted in Nepal Eye Hospital from June 2017 to July 2018. Fifty-two patients with various vitreoretinal diseases were recruited. The main outcome measures included corrected distance visual acuity (CDVA) pr

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Kolenko, Oleg V., Yurii N. Dyachenko, Evgenii L. Sorokin, and Maxim V. Pshenichnov. "Optical reconstructive surgery of the anterior segment of the eye in the far eastern federal district – achievements and unsolved problems." Ophthalmology Journal 13, no. 3 (2021): 47–54. http://dx.doi.org/10.17816/ov33827.

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The aim was to analyze organizational and technical difficulties in introducing modern technologies of optical reconstructive surgery, and to find the options of their elimination. Materials and methods. Organizational arrangements to develop and to introduce into clinical practice modern technologies of optical reconstructive surgery in treatment of corneal opacities of different origin in the Khabarovsk branch of the S. Fedorov Eye Microsurgery Federal State Institution of the Ministry of Health of the Russian Federation has been analyzed. Results and conclusions. An unified regi

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Kolenko, Oleg V., Yurii N. Dyachenko, Evgenii L. Sorokin, and Maxim V. Pshenichnov. "Optical reconstructive surgery of the anterior segment of the eye in the far eastern federal district – achievements and unsolved problems." Ophthalmology journal 13, no. 3 (2021): 47–54. http://dx.doi.org/10.17816/ov33827.

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The aim was to analyze organizational and technical difficulties in introducing modern technologies of optical reconstructive surgery, and to find the options of their elimination. Materials and methods. Organizational arrangements to develop and to introduce into clinical practice modern technologies of optical reconstructive surgery in treatment of corneal opacities of different origin in the Khabarovsk branch of the S. Fedorov Eye Microsurgery Federal State Institution of the Ministry of Health of the Russian Federation has been analyzed. Results and conclusions. An unified regi

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Surovtseva, M. A., K. Y. Krasner, N. A. Bondarenko, et al. "Instrumental and morphological assessment of changes in the mouse corneal stroma in the dynamics of post-traumatic recovery." Fyodorov journal of ophthalmic surgery 140, no. 2S (2024): 72–82. http://dx.doi.org/10.25276/0235-4160-2024-2s-72-82.

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Relevance. Around the world, corneal blindness caused by impaired transparency is one of the leading causes of vision loss. Damage to the cornea can also lead to the development of opacities. The pathogenesis of corneal opacities is based on pathomorphological changes in the corneal stroma. To explore the therapeutic potential of biomedical products and develop new treatments, a standardized and reproducible in vivomodel of corneal stromal injury is needed. In experimental ophthalmology, mouse models of various corneal injuries are widely used, but the dynamics of posttraumatic restoration of

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