Academic literature on the topic 'Segregase'

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Journal articles on the topic "Segregase"

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Chen, C. Y. A., and A. B. Shyu. "Protein segregase meddles in remodeling of mRNA-protein complexes." Genes & Development 27, no. 9 (2013): 980–84. http://dx.doi.org/10.1101/gad.219469.113.

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Skrott, Zdenek, Martin Mistrik, Klaus Kaae Andersen, et al. "Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4." Nature 552, no. 7684 (2017): 194–99. http://dx.doi.org/10.1038/nature25016.

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Ding, Nan, and Qianzheng Zhu. "Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4." Translational Cancer Research 7, S4 (2018): S495—S499. http://dx.doi.org/10.21037/tcr.2018.03.33.

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Davis, Emily J., Christophe Lachaud, Paul Appleton, Thomas J. Macartney, Inke Näthke, and John Rouse. "DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage." Nature Structural & Molecular Biology 19, no. 11 (2012): 1093–100. http://dx.doi.org/10.1038/nsmb.2394.

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Cooney, Ian, Han Han, Michael G. Stewart, et al. "Structure of the Cdc48 segregase in the act of unfolding an authentic substrate." Science 365, no. 6452 (2019): 502–5. http://dx.doi.org/10.1126/science.aax0486.

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The cellular machine Cdc48 functions in multiple biological pathways by segregating its protein substrates from a variety of stable environments such as organelles or multi-subunit complexes. Despite extensive studies, the mechanism of Cdc48 has remained obscure, and its reported structures are inconsistent with models of substrate translocation proposed for other AAA+ ATPases (adenosine triphosphatases). Here, we report a 3.7-angstrom–resolution structure of Cdc48 in complex with an adaptor protein and a native substrate. Cdc48 engages substrate by adopting a helical configuration of substrat
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Bergink, Steven, Tim Ammon, Maximilian Kern, Lothar Schermelleh, Heinrich Leonhardt, and Stefan Jentsch. "Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51–Rad52 interaction." Nature Cell Biology 15, no. 5 (2013): 526–32. http://dx.doi.org/10.1038/ncb2729.

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Zhang, Junrui, Alexandra I. Vancea, Umar F. Shahul Hameed, and Stefan T. Arold. "Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins." Computational and Structural Biotechnology Journal 19 (2021): 3125–32. http://dx.doi.org/10.1016/j.csbj.2021.05.025.

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Jang, Sang-Min, Christophe E. Redon, Haiqing Fu, Fred E. Indig, and Mirit I. Aladjem. "RepID-deficient cancer cells are sensitized to a drug targeting p97/VCP segregase." Molecular & Cellular Toxicology 17, no. 2 (2021): 141–49. http://dx.doi.org/10.1007/s13273-021-00121-0.

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Abstract Background The p97/valosin-containing protein (VCP) complex is a crucial factor for the segregation of ubiquitinated proteins in the DNA damage response and repair pathway. Objective We investigated whether blocking the p97/VCP function can inhibit the proliferation of RepID-deficient cancer cells using immunofluorescence, clonogenic survival assay, fluorescence-activated cell sorting, and immunoblotting. Result p97/VCP was recruited to chromatin and colocalized with DNA double-strand breaks in RepID-deficient cancer cells that undergo spontaneous DNA damage. Inhibition of p97/VCP ind
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Meerang, Mayura, Danilo Ritz, Shreya Paliwal, et al. "The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks." Nature Cell Biology 13, no. 11 (2011): 1376–82. http://dx.doi.org/10.1038/ncb2367.

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Ramadan, Kristijan, Swagata Halder, Katherine Wiseman, and Bruno Vaz. "Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication." Chromosoma 126, no. 1 (2016): 17–32. http://dx.doi.org/10.1007/s00412-016-0587-4.

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Dissertations / Theses on the topic "Segregase"

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Mukherjee, Progya. "In vitro reconstitution of the ubiquitylation and disassembly of the eukaryotic replisome." Thesis, University of Dundee, 2018. https://discovery.dundee.ac.uk/en/studentTheses/1ad1c2bd-1d21-4f9e-bf76-eaad19fcf2d6.

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Maintenance of genomic integrity is dependent on the duplication of chromosomes, only once per cell cycle. Highly conserved mechanisms for the regulation of chromosome replication exists to ensure that the genome is copied only once. The Cdc45-MCM-GINS (CMG) DNA helicase which is the core of the eukaryotic replication complex, has been shown to be extensively regulated by post translational modifications, during its assembly. Therefore, it is not inconceivable that the process to unload the replication complex would also be a conserved and regulated process. In 2014, our lab discovered that th
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Trávníček, Dušan. "Segregace směsí do vozovek pozemních komunikací." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2014. http://www.nusl.cz/ntk/nusl-226616.

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The work deals with the examination of repression and segregation in asphalt mixtures. The theoretical part is monitoring the current situation about the problem of segregation, which mainly refers to the practical adjustments during laying „risking“ asphalt mixtures on the formation of segregated places in the shelter layers of roads. The practical parts of the thesis are summarised measurements on six samples of the most commonly used asphalt mixtures to determine the segregation depending on the selected parameters. The work is describing and valorising a test for determining segregation ac
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Freeman, Nicholas. "The segregated lambda-coalescent." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:fb162fbf-2fa2-40d7-af84-c6e3744e35c1.

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We study a natural generalization of the Λ-coalescent to a spatial continuum. We introduce the process, which is known as the Segregated Λ-coalescent, via its connections to the (non-spatial) Λ-coalescent and the Spatial Λ-Fleming-Viot process. The main new results contained in this thesis are as follows. The Segregated Λ-coalescent has a non-trivial construction which we present here in terms of stochastic flows. We describe the qualitative behaviour of the Segregated Λ-coalescent and compare it to the behaviour of the Λ-coalescent, showing in particular that the Segregated Λ-coalescent has a
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Pernica, Vítězslav. "Segregace ve slitinách železa při odlévání těžkých odlitků." Doctoral thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-263408.

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This thesis is dedicated to the field of manufacture of heavy steel castings with resulting properties which are influenced by long solidification time. During the long solidification time a segregation process of additives in the steel occurs which results in numerous metallurgical defects. The work was intended to observe the macrosegregation effects in the wall of a heavy experimental steel casting respectively a part of a real superheavy casting intended for cement furnaces (weight 210 t). The steel casting for the research was manufactured in the joint-stock company of VHM where such heav
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Kejha, Richard. "Segregace při tuhnutí v austeniticko-feritických korozivzdorných ocelích." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-401533.

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The master thesis deals with processes of segregation in austenitic-ferritic stainless steels. The introductory part consists of characteristics features of austenitic-ferritic steels and theoretical analysis of segregation processes. The second part shows practical measurements of segregation in experimental casting. Macrosegregation was measured on a spectrometric analyzer and simultaneously solved in the simulation program MAGMA. The aim of this thesis is to verify the effect of solidification time and dwell time between liquidus and solidus temperature on the chemical heterogeneity of dupl
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Coelho, L. "Gas percolation through segregated particulate beds." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597802.

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Moving beds are devices where a slow flow of particulate solids moving under the influence of gravity is contacted with a flow of gas. Heat transfer rates, mass transfer rates, and consequently reaction rates, for these devices are often modelled using information from well-packed fixed beds. It has been found, however, that moving beds behave differently from well-packed fixed beds (Paterson <I>et al</I>. 1991). The cause of this different behaviour is a bed structure, which is a consequence of the movement of the particles, that yields gas flow maldistribution (Crawshaw <I>et al</I>., 1993).
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Methadzovic, Almir, and Almir Methadzovic. "Segregated Education in Bosnia and Herzegovina." Thesis, University of Oregon, 2012. http://hdl.handle.net/1794/12452.

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Education in post-Dayton Bosnia and Herzegovina suffers from the serious consequences of ongoing ethno-national conflict. My focus is segregated education in the Federation of Bosnia and Herzegovina generally, particularly the "two schools under one roof" phenomenon. This social abnormality is present almost exclusively in the "Bosniak - Croat" administrative entity. Segregated education, by being an object of political struggle, seriously blocks the society from the necessary path of ethnic reconciliation. In describing and analyzing segregated education, I address the post-Dayton political
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Filimon, Fasola Magdalena. "Gender segregated or gender integrated workgroups?" Thesis, Malmö högskola, Lärarutbildningen (LUT), 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-30999.

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Malmö högskolaLärarutbildningenSkolutveckling och ledarskapVårterminen 2006 Filimon Fasola, Magdalena (2006) Könssegregerat eller könsintegrerat grupparbete? (Gender segregated or gender integrated workgroups?) Malmö: LärarutbildnnigenSyftet med examensarbetet var att undersöka vilken inställning till arbetet i könsintegrerade respektive könssegregerade grupper eleverna har i de klasser jag undervisade i under min vft. Undersökningen gjordes i två klasser, en sjua och en åtta. Arbetet avgränsades av tre frågeställningar:•Vilken inställning har eleverna till arbetet i könsintegrerade respektive
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Kim, Yeon Seok. "Electrical conductivity of segregated network polymer nanocomposites." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1880.

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Zondi, Fanele. "Social stitch : connecting segregated communities through activity." Diss., University of Pretoria, 2012. http://hdl.handle.net/2263/27392.

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The influence of social constructs on the moral fibre and the nature of interactions within a community can never be over emphasized. Social constructs being tangible and intangible elements which form spaces within which communities interact with one another. Where social constructs are chaotic, conflicts within those communities are bound to follow. This has been observed in countries like Rwanda where inequalities among the different communities within the country led to genocide. This dissertation aims to investigate possibilities of using architecture as a tool to create opportunities for
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Books on the topic "Segregase"

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La necedad segregada. Gobierno del Estado de Baja California Sur, Instituto Sudcaliforniano de Cultura, 2011.

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Clarke, Lester J. Certified pure and segregated. Untidy Press II, 1994.

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Bacon, David John. Refining the segregated storage allocation method. University of Toronto, Dept. of Computer Science, 1985.

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Lemon, Anthony. Homes apart: South Africa's segregated cities. P. Chapman Pub., 1991.

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Croix, David de La. To segregate or to integrate: Education politics and democracy. National Bureau of Economic Research, 2007.

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Michelle, Miles, ed. Segregated funds: How to guarantee your financial future. 2nd ed. Stoddart, 2000.

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Worlds apart: Segregated schools in Northern Ireland. Appletree Press, 1985.

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Murray, Dominic. Worlds apart: Segregated schools in Northern Ireland. Appletree, 1985.

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Psychology and selfhood in the segregated South. University of North Carolina Press, 2009.

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Florida's forgotten legacy: Segregated black secondary schools. Mae O. Clemons, 2006.

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Book chapters on the topic "Segregase"

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Browne-Marshall, Gloria J. "Segregated Freedom." In She Took Justice. Routledge, 2020. http://dx.doi.org/10.4324/9781003039273-6.

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Gooch, Jan W. "Segregated Oils." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_10427.

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Boe, Erling E., Shaun R. Harper, and Katherine M. Barghaus. "Segregated by Choice?" In The Charter School Solution. Routledge, 2016. http://dx.doi.org/10.4324/9781315648675-7.

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Souza, Marcelo Lopes de. "Oppressed, segregated, vulnerable." In The Routledge Handbook of Latin American Development. Routledge, 2018. http://dx.doi.org/10.4324/9781315162935-47.

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Walker, Alicia. "Integrated yet segregated." In The Eloquence of Art. Routledge, 2020. http://dx.doi.org/10.4324/9781351185592-22.

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Stocks, Jeffrey D. "The Segregated School." In Supreme Court Decisions. Routledge, 2021. http://dx.doi.org/10.4324/9781003238379-9.

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McGettigan, Timothy, and Earl Smith. "Segregated Buses and Redefined Realities." In A Formula for Eradicating Racism: Debunking White Supremacy. Palgrave Macmillan US, 2016. http://dx.doi.org/10.1057/9781137599759_9.

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Herbert, Angela. "Educated in a Segregated System." In SpringerBriefs in Education. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39235-6_2.

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Gunne, Sorcha. "Liminal Landscapes and Segregated Spaces." In Space, Place, and Gendered Violence in South African Writing. Palgrave Macmillan US, 2014. http://dx.doi.org/10.1057/9781137442680_3.

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Labrecque, Ryan M. "Specialized or Segregated Housing Units." In Routledge Handbook on Offenders with Special Needs. Routledge, 2018. http://dx.doi.org/10.4324/9781315626574-5.

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Conference papers on the topic "Segregase"

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He, Jinshan, Gulzar Wani, Qianzheng Zhu, and Altaf A. Wani. "Abstract 2565: VCP/p97 segregase-mediated regulation of chromatin-bound PTEN stability." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-2565.

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Mistrik, Martin, Zdenek Skrott, Marian Hajduch, et al. "Abstract LB-264: Alcohol-aversion drug disulfiram targets cancer via p97 segregase adaptor NPL4." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-lb-264.

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Wells, Patrick. "Tailings philosophies — to segregate or not to segregate." In Thirteenth International Seminar on Paste and Thickened Tailings. Australian Centre for Geomechanics, Perth, 2010. http://dx.doi.org/10.36487/acg_rep/1063_39_wells.

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Žítek, Vladimír. "Prostorová segregace ekonomických aktivit." In 16. mezinárodní kolokvium o regionálních vědách. Sborník příspěvků. (16th International Colloquium on Regional Sciences. Conference Proceedings.). Masaryk University Press, 2013. http://dx.doi.org/10.5817/cz.muni.p210-6257-2013-17.

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Walkingshaw, Martin. "The Role of the National Low Level Waste Repository Operator in Delivering New Solutions for the Management of Low Level Wastes in the UK." In ASME 2009 12th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2009. http://dx.doi.org/10.1115/icem2009-16217.

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The UK National Low Level Waste Repository (LLWR) is located near to the village of Drigg in West Cumbria. It is the principal site for disposal of solid Low Level Radioactive Waste (LLW) in the United Kingdom. This paper describes the program of work currently being undertaken by the site’s operators, (LLW Repository Ltd and its newly appointed Parent Body Organisation), to extend the life of the LLWR and reduce the overall cost of LLW management to the UK taxpayer. The current focus of this program is to prevent disposal capacity being taken up at LLWR by waste types which lend themselves to
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Hitchen, I., and C. de Salis. "Segregated integration - the paradox." In IET 3rd Annual Seminar on Power Generation Control. Building Flexibility & Sustainability into Plants. IEE, 2008. http://dx.doi.org/10.1049/ic.2008.0677.

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Na, Suok-Min, and Alison B. Flatau. "Surface Segregation of Sulfur and Its Effect on Surface-Energy-Induced Selective Grain Growth in Magnetostrictive Fe-Ga-B Alloy." In ASME 2008 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2008. http://dx.doi.org/10.1115/smasis2008-506.

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The surface-energy-induced selective grain growth with a specific plane can be governed in polycrystalline Fe-Ga-B alloys doped with sulfur. The segregated sulfur during texture annealing played an important role in controlling the surface energy to induce the selective growth of {100} or {110} grains, corresponding to maximum magnetostrictive performance, along &lt;001&gt; orientation with respect to rolling direction. The results show that sulfur diffuses (adsorbs) from bulk interior (sulfur atmosphere) then segregates on the surface. The amount of segregated sulfur increases with an increas
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Jong, C. J. "Segregate Applications at System Level to Eliminate Security Problems." In Sixth IEEE International Symposium on Cluster Computing and the Grid. IEEE, 2006. http://dx.doi.org/10.1109/ccgrid.2006.1630926.

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Verleden, Stijn, Joshua Yang, Tara Sigdel, et al. "Gene expression markers to segregate lung transplant rejection phenotypes." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.oa1992.

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Singh, Neha, and Deepali Virmani. "A Novel Algorithm to Segregate Suspicious node in FzMAI." In 2020 2nd International Conference on Advances in Computing, Communication Control and Networking (ICACCCN). IEEE, 2020. http://dx.doi.org/10.1109/icacccn51052.2020.9362965.

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Reports on the topic "Segregase"

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Davis, Donald, Jonathan Dingel, Joan Monras, and Eduardo Morales. How Segregated is Urban Consumption? National Bureau of Economic Research, 2017. http://dx.doi.org/10.3386/w23822.

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de la Croix, David, and Matthias Doepke. To Segregate or to Integrate: Education Politics and Democracy. National Bureau of Economic Research, 2007. http://dx.doi.org/10.3386/w13319.

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Searcy, K., G. M. Bltyhe, and W. A. Steen. FGD Additives to Segregate and Sequester Mercury in Solid Byproducts - Final Report. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1040032.

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Shippy, J. L. III, and J. S. Watson. Application of sedimentation model to uniform and segregated fluidized beds. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/6080665.

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Saltzman, Eric S., and Anthony J. Hynes. Real Time Detection of Sodium in Size-segregated Marine Aerosols. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada634286.

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Hynes, Anthony J., and Eric S. Saltzman. Real Time Detection of Sodium in Size-Segregated Marine Aerosols. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada628940.

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Williams, Ronald, Gary Duncan, and Thomas White. Sources, Measurements, and Effects of Segregated Hot Mix Asphalt Pavement. Purdue University, 1996. http://dx.doi.org/10.5703/1288284313316.

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Hynes, Anthony J. Real Time Detection of Sodium in Size-Segregated Marine Aerosols. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada626237.

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Margo, Robert. Segregated Schools and the Mobility Hypothesis: A Model of Local Government Discrimination. National Bureau of Economic Research, 1990. http://dx.doi.org/10.3386/h0017.

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Margo, Robert. Education Achievement in Segregated School Systems: The Effects of "Separate-But-Equal". National Bureau of Economic Research, 1985. http://dx.doi.org/10.3386/w1620.

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