Log in

Relevant bibliographies by topics / Segregase / Journal articles

To see the other types of publications on this topic, follow the link: Segregase.

Journal articles on the topic 'Segregase'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Segregase.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Chen, C. Y. A., and A. B. Shyu. "Protein segregase meddles in remodeling of mRNA-protein complexes." Genes & Development 27, no. 9 (2013): 980–84. http://dx.doi.org/10.1101/gad.219469.113.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Skrott, Zdenek, Martin Mistrik, Klaus Kaae Andersen, et al. "Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4." Nature 552, no. 7684 (2017): 194–99. http://dx.doi.org/10.1038/nature25016.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Ding, Nan, and Qianzheng Zhu. "Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4." Translational Cancer Research 7, S4 (2018): S495—S499. http://dx.doi.org/10.21037/tcr.2018.03.33.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Davis, Emily J., Christophe Lachaud, Paul Appleton, Thomas J. Macartney, Inke Näthke, and John Rouse. "DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage." Nature Structural & Molecular Biology 19, no. 11 (2012): 1093–100. http://dx.doi.org/10.1038/nsmb.2394.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Cooney, Ian, Han Han, Michael G. Stewart, et al. "Structure of the Cdc48 segregase in the act of unfolding an authentic substrate." Science 365, no. 6452 (2019): 502–5. http://dx.doi.org/10.1126/science.aax0486.

Full text

Abstract:

The cellular machine Cdc48 functions in multiple biological pathways by segregating its protein substrates from a variety of stable environments such as organelles or multi-subunit complexes. Despite extensive studies, the mechanism of Cdc48 has remained obscure, and its reported structures are inconsistent with models of substrate translocation proposed for other AAA+ ATPases (adenosine triphosphatases). Here, we report a 3.7-angstrom–resolution structure of Cdc48 in complex with an adaptor protein and a native substrate. Cdc48 engages substrate by adopting a helical configuration of substrat

APA, Harvard, Vancouver, ISO, and other styles

6

Bergink, Steven, Tim Ammon, Maximilian Kern, Lothar Schermelleh, Heinrich Leonhardt, and Stefan Jentsch. "Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51–Rad52 interaction." Nature Cell Biology 15, no. 5 (2013): 526–32. http://dx.doi.org/10.1038/ncb2729.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Zhang, Junrui, Alexandra I. Vancea, Umar F. Shahul Hameed, and Stefan T. Arold. "Versatile control of the CDC48 segregase by the plant UBX-containing (PUX) proteins." Computational and Structural Biotechnology Journal 19 (2021): 3125–32. http://dx.doi.org/10.1016/j.csbj.2021.05.025.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Jang, Sang-Min, Christophe E. Redon, Haiqing Fu, Fred E. Indig, and Mirit I. Aladjem. "RepID-deficient cancer cells are sensitized to a drug targeting p97/VCP segregase." Molecular & Cellular Toxicology 17, no. 2 (2021): 141–49. http://dx.doi.org/10.1007/s13273-021-00121-0.

Full text

Abstract:

Abstract Background The p97/valosin-containing protein (VCP) complex is a crucial factor for the segregation of ubiquitinated proteins in the DNA damage response and repair pathway. Objective We investigated whether blocking the p97/VCP function can inhibit the proliferation of RepID-deficient cancer cells using immunofluorescence, clonogenic survival assay, fluorescence-activated cell sorting, and immunoblotting. Result p97/VCP was recruited to chromatin and colocalized with DNA double-strand breaks in RepID-deficient cancer cells that undergo spontaneous DNA damage. Inhibition of p97/VCP ind

APA, Harvard, Vancouver, ISO, and other styles

9

Meerang, Mayura, Danilo Ritz, Shreya Paliwal, et al. "The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks." Nature Cell Biology 13, no. 11 (2011): 1376–82. http://dx.doi.org/10.1038/ncb2367.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Ramadan, Kristijan, Swagata Halder, Katherine Wiseman, and Bruno Vaz. "Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication." Chromosoma 126, no. 1 (2016): 17–32. http://dx.doi.org/10.1007/s00412-016-0587-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Lundgren, Josefin, Patrick Masson, Zahra Mirzaei, and Patrick Young. "Identification and Characterization of a Drosophila Proteasome Regulatory Network." Molecular and Cellular Biology 25, no. 11 (2005): 4662–75. http://dx.doi.org/10.1128/mcb.25.11.4662-4675.2005.

Full text

Abstract:

ABSTRACT Maintaining adequate proteasomal proteolytic activity is essential for eukaryotic cells. For metazoan cells, little is known about the composition of genes that are regulated in the proteasome network or the mechanisms that modulate the levels of proteasome genes. Previously, two distinct treatments have been observed to induce 26S proteasome levels in Drosophila melanogaster cell lines, RNA interference (RNAi)-mediated inhibition of the 26S proteasome subunit Rpn10/S5a and suppression of proteasome activity through treatment with active-site inhibitors. We have carried out genome arr

APA, Harvard, Vancouver, ISO, and other styles

12

Braun, S. "Role of the ubiquitin-selective CDC48UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates." EMBO Journal 21, no. 4 (2002): 615–21. http://dx.doi.org/10.1093/emboj/21.4.615.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Lin, Yao-Tang, James Prendergast, and Finn Grey. "The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication." PLOS Pathogens 13, no. 5 (2017): e1006329. http://dx.doi.org/10.1371/journal.ppat.1006329.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Torrecilla, Ignacio, Judith Oehler, and Kristijan Ramadan. "The role of ubiquitin-dependent segregase p97 (VCP or Cdc48) in chromatin dynamics after DNA double strand breaks." Philosophical Transactions of the Royal Society B: Biological Sciences 372, no. 1731 (2017): 20160282. http://dx.doi.org/10.1098/rstb.2016.0282.

Full text

Abstract:

DNA double strand breaks (DSBs) are the most cytotoxic DNA lesions and, if not repaired, lead to chromosomal rearrangement, genomic instability and cell death. Cells have evolved a complex network of DNA repair and signalling molecules which promptly detect and repair DSBs, commonly known as the DNA damage response (DDR). The DDR is orchestrated by various post-translational modifications such as phosphorylation, methylation, ubiquitination or SUMOylation. As DSBs are located in complex chromatin structures, the repair of DSBs is engineered at two levels: (i) at sites of broken DNA and (ii) at

APA, Harvard, Vancouver, ISO, and other styles

15

He, Jinshan, Qianzheng Zhu, Gulzar Wani, Nidhi Sharma, and Altaf A. Wani. "Valosin-containing Protein (VCP)/p97 Segregase Mediates Proteolytic Processing of Cockayne Syndrome Group B (CSB) in Damaged Chromatin." Journal of Biological Chemistry 291, no. 14 (2016): 7396–408. http://dx.doi.org/10.1074/jbc.m115.705350.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Gwon, Youngdae, Brian A. Maxwell, Regina-Maria Kolaitis, Peipei Zhang, Hong Joo Kim, and J. Paul Taylor. "Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner." Science 372, no. 6549 (2021): eabf6548. http://dx.doi.org/10.1126/science.abf6548.

Full text

Abstract:

Stress granules are dynamic, reversible condensates composed of RNA and protein that assemble in eukaryotic cells in response to a variety of stressors and are normally disassembled after stress is removed. The composition and assembly of stress granules is well understood, but little is known about the mechanisms that govern disassembly. Impaired disassembly has been implicated in some diseases including amyotrophic lateral sclerosis, frontotemporal dementia, and multisystem proteinopathy. Using cultured human cells, we found that stress granule disassembly was context-dependent: Specifically

APA, Harvard, Vancouver, ISO, and other styles

17

Burjanek, Aleš. "Segregation." Czech Sociological Review 33, no. 4 (1997): 423–34. http://dx.doi.org/10.13060/00380288.1997.33.4.04.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Wang, Dejie, Jian Ma, Maria Victoria Botuyan, et al. "ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication." Science Advances 7, no. 25 (2021): eabd9208. http://dx.doi.org/10.1126/sciadv.abd9208.

Full text

Abstract:

53BP1 activates nonhomologous end joining (NHEJ) and inhibits homologous recombination (HR) repair of DNA double-strand breaks (DSBs). Dissociation of 53BP1 from DSBs and consequent activation of HR, a less error-prone pathway than NHEJ, helps maintain genome integrity during DNA replication; however, the underlying mechanisms are not fully understood. Here, we demonstrate that E3 ubiquitin ligase SPOP promotes HR during S phase of the cell cycle by excluding 53BP1 from DSBs. In response to DNA damage, ATM kinase–catalyzed phosphorylation of SPOP causes a conformational change in SPOP, reveale

APA, Harvard, Vancouver, ISO, and other styles

19

He, Jinshan, Qianzheng Zhu, Gulzar Wani, and Altaf A. Wani. "UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein." Oncotarget 8, no. 7 (2016): 11004–19. http://dx.doi.org/10.18632/oncotarget.14205.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Priego Moreno, Sara, Rebecca M. Jones, Divyasree Poovathumkadavil, Shaun Scaramuzza, and Agnieszka Gambus. "Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity." Life Science Alliance 2, no. 2 (2019): e201900390. http://dx.doi.org/10.26508/lsa.201900390.

Full text

Abstract:

We have shown previously that the process of replication machinery (replisome) disassembly at the termination of DNA replication forks in the S-phase is driven through polyubiquitylation of one of the replicative helicase subunits (Mcm7) by Cul2LRR1 ubiquitin ligase. Interestingly, upon inhibition of this pathway in Caenorhabditis elegans embryos, the replisomes retained on chromatin were unloaded in the subsequent mitosis. Here, we show that this mitotic replisome disassembly pathway exists in Xenopus laevis egg extract and we determine the first elements of its regulation. The mitotic disass

APA, Harvard, Vancouver, ISO, and other styles

21

Blythe, Emily E., Kristine C. Olson, Vincent Chau, and Raymond J. Deshaies. "Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy." Proceedings of the National Academy of Sciences 114, no. 22 (2017): E4380—E4388. http://dx.doi.org/10.1073/pnas.1706205114.

Full text

Abstract:

p97 is a “segregase” that plays a key role in numerous ubiquitin (Ub)-dependent pathways such as ER-associated degradation. It has been hypothesized that p97 extracts proteins from membranes or macromolecular complexes to enable their proteasomal degradation; however, the complex nature of p97 substrates has made it difficult to directly observe the fundamental basis for this activity. To address this issue, we developed a soluble p97 substrate—Ub-GFP modified with K48-linked ubiquitin chains—for in vitro p97 activity assays. We demonstrate that WT p97 can unfold proteins and that this activit

APA, Harvard, Vancouver, ISO, and other styles

22

Nechushtan, Hovav, and Tamar Peretz. "There must be another way—disulfiram and cancer treatment: editorial on “Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4”." Translational Cancer Research 7, S4 (2018): S491—S494. http://dx.doi.org/10.21037/tcr.2018.03.34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Librandi, Rita. "Segregare, segregazione – sequestrare, sequestrazione." XI, 2019/4 (ottobre-dicembre) 11, no. 4 (2019): 42–43. http://dx.doi.org/10.35948/2532-9006/2020.3249.

Full text

Abstract:

Alcuni lettori chiedono se in ambiti specialistici sia opportuno usare il sostantivo segregazione e il verbo segregare in alternativa ad altre forme (es: “sequestrazione o segregazione della CO2?"; “Legge della segregazione o separazione di Mendel?”). Altri chiedono se il verbo segregare può essere usato anche riferendosi a oggetti (es: "Materiale da segregare. Non conforme!" parlando di vetro; "la zona è segregata" per uno spazio non accessibile; “segregare due materiali altamente corrosivi interponendo un terzo materiale isolante”). Infine &nbsp;un lettore chiede quale sia la posizione d

APA, Harvard, Vancouver, ISO, and other styles

24

Majera, Dusana, Zdenek Skrott, Katarina Chroma, Joanna Maria Merchut-Maya, Martin Mistrik, and Jiri Bartek. "Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway." Cells 9, no. 2 (2020): 469. http://dx.doi.org/10.3390/cells9020469.

Full text

Abstract:

Research on repurposing the old alcohol-aversion drug disulfiram (DSF) for cancer treatment has identified inhibition of NPL4, an adaptor of the p97/VCP segregase essential for turnover of proteins involved in multiple pathways, as an unsuspected cancer cell vulnerability. While we reported that NPL4 is targeted by the anticancer metabolite of DSF, the bis-diethyldithiocarbamate-copper complex (CuET), the exact, apparently multifaceted mechanism(s) through which the CuET-induced aggregation of NPL4 kills cancer cells remains to be fully elucidated. Given the pronounced sensitivity to CuET in t

APA, Harvard, Vancouver, ISO, and other styles

25

Fullbright, George, Halley B. Rycenga, Jordon D. Gruber, and David T. Long. "p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair." Molecular and Cellular Biology 36, no. 23 (2016): 2983–94. http://dx.doi.org/10.1128/mcb.00434-16.

Full text

Abstract:

Interstrand cross-links (ICLs) are extremely toxic DNA lesions that create an impassable roadblock to DNA replication. When a replication fork collides with an ICL, it triggers a damage response that promotes multiple DNA processing events required to excise the cross-link from chromatin and resolve the stalled replication fork. One of the first steps in this process involves displacement of the CMG replicative helicase (comprised of Cdc45, MCM2-7, and GINS), which obstructs the underlying cross-link. Here we report that the p97/Cdc48/VCP segregase plays a critical role in ICL repair by unload

APA, Harvard, Vancouver, ISO, and other styles

26

Nie, Minghua, Aaron Aslanian, John Prudden, et al. "Dual Recruitment of Cdc48 (p97)-Ufd1-Npl4 Ubiquitin-selective Segregase by Small Ubiquitin-like Modifier Protein (SUMO) and Ubiquitin in SUMO-targeted Ubiquitin Ligase-mediated Genome Stability Functions." Journal of Biological Chemistry 287, no. 35 (2012): 29610–19. http://dx.doi.org/10.1074/jbc.m112.379768.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Timisela, Julian, Aca A. Anakotta, Adriana Hiariej, and Edizon Jambormias. "Korelasi Genotipe dan Fenotipe Antar Sifat Kuantitatif Pada Populasi Segregasi Transgresif Kacang Hijau." JURNAL BUDIDAYA PERTANIAN 16, no. 1 (2020): 21–30. http://dx.doi.org/10.30598/jbdp.2020.16.1.21.

Full text

Abstract:

Mung bean (Vigna radiata L. Wilczek) is one of the food plants as a source of vegetable protein for humans. One of these is a population of transgressive segregation resulting from crossing in mung beans. This research aims to estimate the correlation between genotype and phenotype values between quantitative traits in the transgressive segregation population of mung beans. Genetic material was 11 lines of transgressive segregated in the selection generation S2:2 of varieties Mamasa Lere Butnem × Lasafu Lere Butnem crosses. Genotype correlation analysis was obtained from the decomposition of

APA, Harvard, Vancouver, ISO, and other styles

28

Antolin, Michael F., Christopher F. Bosio, Julie Cotton, William Sweeney, Michael R. Strand, and William C. Black. "Intensive Linkage Mapping in a Wasp (Bracon hebetor) and a Mosquito (Aedes aegypti) With Single-Strand Conformation Polymorphism Analysis of Random Amplified Polymorphic DNA Markers." Genetics 143, no. 4 (1996): 1727–38. http://dx.doi.org/10.1093/genetics/143.4.1727.

Full text

Abstract:

Abstract The use of random amplified polymorphic DNA from the polymerase chain reaction (RAPD-PCR) allows efficient construction of saturated linkage maps. However, when analyzed by agarose gel electrophoresis, most RAPD-PCR markers segregate as dominant alleles, reducing the amount of linkage information obtained. We describe the use of single strand conformation polymorphism (SSCP) analysis of RAPD markers to generate linkage maps in a haplodiploid parasitic wasp Bracon (Habrobracon) hebetor and a diploid mosquito, Aedes aegypti. RAPD-SSCP analysis revealed segregation of codominant alleles

APA, Harvard, Vancouver, ISO, and other styles

29

Meikle, R. D. "British willows; some hybrids and some problems." Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences 98 (1992): 13–20. http://dx.doi.org/10.1017/s0269727000007429.

Full text

Abstract:

SynopsisThe paper deals with three problem areas in the taxonomy of British willows: (1) the widespread occurrence in Perthshire and neighbouring counties of an intermediate between Salix myrsinifolia Salisb. and S. phylicifolia L., apparently of hybrid origin, though growing in an area where typical S. phylicifolia has yet to be found; (2) the complex taxonomy of the British Sallows, where two common aggregate species, Salix cinerea L. and S. caprea L., are each represented by two segregates; a third, S. aurita L., may also comprise more than one segregate; all three species interbreed, as do

APA, Harvard, Vancouver, ISO, and other styles

30

Vogeler, Iris, Pierre Beukes, Alvaro Romera, and Rogerio Cichota. "Estimating nitrous oxide emissions from a dairy farm using a mechanistic, whole farm model and segregated emission factors for New Zealand." Soil Research 50, no. 3 (2012): 188. http://dx.doi.org/10.1071/sr12064.

Full text

Abstract:

Nitrous oxide (N2O) emissions from agriculture are generally estimated using default IPCC emission factors (EFs) despite the large variation in measured EFs. We used a classification and regression tree (CART) analysis to segregate measured EFs from direct emissions from urine patches and fertiliser and effluent applications, based on temporal and site-specific factors. These segregated EFs were linked to simulations from the DairyNZ Whole Farm Model to obtain N2O emissions for a typical pasture-based dairy farm in New Zealand. The N2O emissions from urine patches, dung pads, and fertiliser an

APA, Harvard, Vancouver, ISO, and other styles

31

Howard, Sasha R., Roberto Oleari, Ariel Poliandri, et al. "HS6ST1 Insufficiency Causes Self-Limited Delayed Puberty in Contrast With Other GnRH Deficiency Genes." Journal of Clinical Endocrinology & Metabolism 103, no. 9 (2018): 3420–29. http://dx.doi.org/10.1210/jc.2018-00646.

Full text

Abstract:

Abstract Context Self-limited delayed puberty (DP) segregates in an autosomal-dominant pattern, but the genetic basis is largely unknown. Although DP is sometimes seen in relatives of patients with hypogonadotropic hypogonadism (HH), mutations in genes known to cause HH that segregate with the trait of familial self-limited DP have not yet been identified. Objective To assess the contribution of mutations in genes known to cause HH to the phenotype of self-limited DP. Design, Patients, and Setting We performed whole-exome sequencing in 67 probands and 93 relatives from a large cohort of famili

APA, Harvard, Vancouver, ISO, and other styles

32

,, Roberdi, Sobir ,, Sudirman Yahya, Nurita Toruan-Mathius, and Tony Liwang. "Identification of Gene Related to Hard Bunch Phenotype in Oil Palm (Elaeis guineensis Jacq.)." Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) 43, no. 2 (2015): 147. http://dx.doi.org/10.24831/jai.v43i2.10421.

Full text

Abstract:

<p>ABSTRACT</p><p>Molecular genetic analysis of hard bunch phenomenon in oil palm was done in order to elucidate the role of genetic factor underlying hard bunch in oil palm plantation. The aim of this study was to identify the AFLP primer combination that co-segregates with hard bunch phenotype related gene in oil palm. Molecular analysis was done by bulk segregant analysis approach. DNA was isolated from leaves of the normal and hard bunch palm. DNA from ten individual palms from each category were pooled and used as a template. A total of 56 AFLP primer combinations were s

APA, Harvard, Vancouver, ISO, and other styles

33

Matoušek, Roman. "New Municipal Housing Construction, Decision-making, and Risks of Segregation: A Case Study in Rudoltice." Czech Sociological Review 50, no. 2 (2014): 211–32. http://dx.doi.org/10.13060/00380288.2014.50.2.77.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Buller, R. S., M. Sitbon, and J. L. Portis. "The endogenous mink cell focus-forming (MCF) gp70 linked to the Rmcf gene restricts MCF virus replication in vivo and provides partial resistance to erythroleukemia induced by Friend murine leukemia virus." Journal of Experimental Medicine 167, no. 5 (1988): 1535–46. http://dx.doi.org/10.1084/jem.167.5.1535.

Full text

Abstract:

The Rmcf locus restricts the in vitro replication of mink cell focus-forming (MCF) viruses in cell cultures derived from mice carrying the resistance allele. Previously we reported that in cell cultures from first backcross progeny, this Rmcf-linked restriction segregates with the expression of an endogenous retroviral gp70 serologically related to that of MCF viruses. The current report details the results of genetic studies designed to examine the possible association of this endogenous gp70 with resistance of mice to Friend murine leukemia virus (F-MuLV)-induced erythroleukemia. This env ge

APA, Harvard, Vancouver, ISO, and other styles

35

Checkoway, Barry. "Adults as allies to young people striving for social justice." Queensland Review 24, no. 1 (2017): 93–99. http://dx.doi.org/10.1017/qre.2017.12.

Full text

Abstract:

AbstractWhat are some strategies for preparing adults as allies to young people striving for social justice in metropolitan areas that are becoming more segregated and more diverse? This question is especially important at a time when young people are aware of segregation, and want to communicate and collaborate with others who are different from themselves, across the boundaries that segregate them. Some adults successfully support and engage with youth as adult allies. Many adults are, however, conditioned to position youth in secondary roles, and would benefit from more information about ho

APA, Harvard, Vancouver, ISO, and other styles

36

Ishchuk, V., N. Spiridonov, and V. Sobolev. "Nanostructures formation in ferroelectrics in the process of phase transformation." Journal of Advanced Dielectrics 04, no. 04 (2014): 1450031. http://dx.doi.org/10.1142/s2010135x14500313.

Full text

Abstract:

Inhomogeneous states caused by the coexistence of the ferroelectric (FE) and antiferroelectric (AFE) phases in lead–zirconate–titanate based solid solutions have been investigated. It has been found that the domains of the FE and AFE phases with sizes of the order of 20 nm to 30 nm coexist in the bulk of the samples due to a small difference in the free energies of these phases. The coherent character of the interphase boundaries (IPBs) leads to the concentration of the elastic stresses along these boundaries. These elastic stresses cause the local decomposition of the solid solution and forma

APA, Harvard, Vancouver, ISO, and other styles

37

Anda, Silje, Erik Boye, Kay Oliver Schink, and Beata Grallert. "Cosegregation of asymmetric features during cell division." Open Biology 11, no. 8 (2021): 210116. http://dx.doi.org/10.1098/rsob.210116.

Full text

Abstract:

Cellular asymmetry plays a major role in the ageing and evolution of multicellular organisms. However, it remains unknown how the cell distinguishes ‘old’ from ‘new’ and whether asymmetry is an attribute of highly specialized cells or a feature inherent in all cells. Here, we investigate the segregation of three asymmetric features: old and new DNA, the spindle pole body (SPB, the centrosome analogue) and the old and new cell ends, using a simple unicellular eukaryote, Schizosaccharomyces pombe . To our knowledge, this is the first study exploring three asymmetric features in the same cells. W

APA, Harvard, Vancouver, ISO, and other styles

38

Guerra, Cesar E., and David B. Kaback. "The Role of Centromere Alignment in Meiosis I Segregation of Homologous Chromosomes in Saccharomyces cerevisiae." Genetics 153, no. 4 (1999): 1547–60. http://dx.doi.org/10.1093/genetics/153.4.1547.

Full text

Abstract:

AbstractDuring meiosis, homologous chromosomes pair and then segregate from each other at the first meiotic division. Homologous centromeres appear to be aligned when chromosomes are paired. The role of centromere alignment in meiotic chromosome segregation was investigated in Saccharomyces cerevisiae diploids that contained one intact copy of chromosome I and one copy bisected into two functional centromere-containing fragments. The centromere on one fragment was aligned with the centromere on the intact chromosome while the centromere on the other fragment was either aligned or misaligned. F

APA, Harvard, Vancouver, ISO, and other styles

39

Gul, Faruk, and Wolfgang Pesendorfer. "Strategic Redistricting." American Economic Review 100, no. 4 (2010): 1616–41. http://dx.doi.org/10.1257/aer.100.4.1616.

Full text

Abstract:

Two parties choose redistricting plans to maximize their probability of winning a majority in the House of Representatives. In the unique equilibrium, parties maximally segregate their opponents' supporters but pool their own supporters into uniform districts. Ceteris paribus, the stronger party segregates more than the weaker one, and the election outcome is biased in the stronger party's favor and against the party whose supporters are easier to identify. We incorporate policy choice into our redistricting game and find that when one party controls redistricting, the equilibrium policy is bi

APA, Harvard, Vancouver, ISO, and other styles

40

Beecham, Gary W., Badri Vardarajan, Elizabeth Blue, et al. "Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease." Neurology Genetics 4, no. 6 (2018): e286. http://dx.doi.org/10.1212/nxg.0000000000000286.

Full text

Abstract:

ObjectiveTo identify genetic variation influencing late-onset Alzheimer disease (LOAD), we used a large data set of non-Hispanic white (NHW) extended families multiply-affected by LOAD by performing whole genome sequencing (WGS).MethodsAs part of the Alzheimer Disease Sequencing Project, WGS data were generated for 197 NHW participants from 42 families (affected individuals and unaffected, elderly relatives). A two-pronged approach was taken. First, variants were prioritized using heterogeneity logarithm of the odds (HLOD) and family-specific LOD scores as well as annotations based on function

APA, Harvard, Vancouver, ISO, and other styles

41

Irwin, S. V., R. V. Kesseli, W. Waycott, E. J. Ryder, J. J. Cho, and R. W. Michelmore. "Identification of PCR-based markers flanking the recessive LMV resistance gene mo1 in an intraspecific cross in lettuce." Genome 42, no. 5 (1999): 982–86. http://dx.doi.org/10.1139/g99-055.

Full text

Abstract:

Molecular markers flanking the recessive resistance gene mo1 were identified following analysis of two segregating populations. Generation of a population from a crisphead × crisphead cross of Lactuca sativa that segregated for resistance conferred by the mo12 allele, but not morphological traits, was required for accurate mapping of the gene. Resistance was best assessed by symptom development after inoculating F3 families with the common pathotype II isolate of lettuce mosaic virus (LMV). Bulked segregant analysis for RAPD (random amplified polymorphic DNA) markers using one population, foll

APA, Harvard, Vancouver, ISO, and other styles

42

Izady, Michael M. R. "Urban Unplanning: How Violence, Walls, and Segregation Destroyed the Urban Fabric of Baghdad." Journal of Planning History 19, no. 1 (2019): 52–68. http://dx.doi.org/10.1177/1538513219830106.

Full text

Abstract:

Baghdad was formerly a relatively well-planned and thriving city, serving as home to a multitude of intertwined ethnoreligious groups. As a result of the American-led invasion, and five years of urban civil war that followed, the city was segregated along ethnic lines. The effects of comprehensive wall building to segregate the warring urban neighborhood have altered the very fabric of the city and have undone the earlier rational urban planning. Contemporary Baghdad shares much with cities like Belfast that have been physically divided due to civil unrest. The author visited Baghdad a number

APA, Harvard, Vancouver, ISO, and other styles

43

Bai, Xiaolong, Boyuan Ban, Jingwei Li, Zhijian Peng, and Jian Chen. "Distribution Behavior of B and P during Al-Si Melt Directional Solidification with Open-Ended Crucible." High Temperature Materials and Processes 37, no. 3 (2018): 201–8. http://dx.doi.org/10.1515/htmp-2016-0127.

Full text

Abstract:

AbstractDistribution behavior of B and P during directional solidification of Al-20Si, Al-30Si and Al-40Si alloys has been investigated. Macrostructure of the Al-Si alloy ingots and concentration profile of elements B and P reveal that the elements segregate to eutectic Al-Si melt during growth of primary Si flakes, and P gradually segregates to the top of the ingots during directional solidification. An apparent segregation coefficient, ka, is introduced to describe the segregation behavior of B and P between the primary Si and the Al-Si melt and compared with thermodynamic theoretical equili

APA, Harvard, Vancouver, ISO, and other styles

44

Jiang, Bingyao, Xianghuai Liu, Shichang Zou, Jian Sun, and Jian Wang. "Atomistic computer study on Mg segregation in the Ni3Al grain boundary." Journal of Materials Research 13, no. 7 (1998): 1741–44. http://dx.doi.org/10.1557/jmr.1998.0242.

Full text

Abstract:

The embedded atom method (EAM) was applied to calculate the energy on Mg doping in polycrystalline Ni3Al. The EAM predicted the energy of Mg in Al site in grain boundary is lower than that of Mg in Ni site and much lower than that of Mg in Al or Ni site in bulk and in free surface. It means that Mg would segregate to grain boundary rather than bulk and free surface and Mg will favor to be the substitute of Al rather than of Ni in grain boundary. These results were consistent with the experiments that Mg segregated to grain boundaries with Al depletion and Ni enrichment.

APA, Harvard, Vancouver, ISO, and other styles

45

Li, Bin, and Ellen D. Williams. "Stability of the YBa2Cu3O7−x−Si interface." Journal of Materials Research 6, no. 8 (1991): 1634–40. http://dx.doi.org/10.1557/jmr.1991.1634.

Full text

Abstract:

Electron spectroscopies were used to study the reaction of Si and SiO2 layers with high-Tc superconductors at room temperature and under annealing conditions. The superconductor samples include YBa2Cu3O7 ceramic and thin film samples as well as GdBa2Cu3O7 ceramic samples. The results show that the Si overlayers withdraw oxygen from the superconductor and form an interfacial layer of Si oxide at room temperature. Annealing increases the reaction rate so that films as thick as 30 Å become completely oxidized following annealing above approximately 100 °C. Ba segregates to the surface from the bu

APA, Harvard, Vancouver, ISO, and other styles

46

TERRY, R. S., A. M. DUNN, and J. E. SMITH. "Segregation of a microsporidian parasite during host cell mitosis." Parasitology 118, no. 1 (1999): 43–48. http://dx.doi.org/10.1017/s0031182098003540.

Full text

Abstract:

We investigated the segregation of an intracellular microsporidian parasite during host cell division. A time-course experiment was carried out to examine the distribution of parasites relative to host chromosomal DNA via light and electron microscopy. Fluorescent light microscopy and EM studies showed that the parasite lay in the perinuclear zone of the host cell during interphase and segregated to daughter cells at mitosis. At metaphase, the parasite was frequently closely associated with host microtubules and mitochondria. Electron-dense bridges were observed between the parasites and the h

APA, Harvard, Vancouver, ISO, and other styles

47

Johnson, Richard, and Desmond King. "‘Race was a motivating factor’: re-segregated schools in the American states." Journal of International and Comparative Social Policy 35, no. 1 (2019): 75–95. http://dx.doi.org/10.1080/21699763.2018.1526701.

Full text

Abstract:

AbstractDuring the Obama presidency, Republicans made major gains in state legislative elections, especially in the South and the Midwest. Republicans’ control grew from 13 legislatures in 2009 to 32 in 2017. A major but largely unexamined consequence of this profound shift in state-level partisan control was the resurgence of efforts to re-segregate public education. We examine new re-segregation policies, especially school district secession and anti-busing laws, which have passed in these states. We argue that the marked reversal in desegregation patterns and upturn in re-segregated school

APA, Harvard, Vancouver, ISO, and other styles

48

Pritchard, Catrin A., and Peter N. Goodfellow. "Genetic analysis of the human Y chromosome by chromosome-mediated gene transfer." Development 101, Supplement (1987): 59–65. http://dx.doi.org/10.1242/dev.101.supplement.59.

Full text

Abstract:

Chromosome-mediated gene transfer (CMGT) can be used to segregate fragments of human chromosomes in human—rodent hybrid cells. As with all somatic cell genetics methods, a selection technique is needed to isolate the hybrid cell lines produced by CMGT. Expression of the MIC2 gene product on the cell surface (the 12E7 antigen) provides an endogenous selectable marker for the human Y chromosome. Using chromosome transfer followed by separation of 12E7 antigen-positive cells on the fluorescence-activated cell sorter, a series of cell lines containing segregated fragments of the Y chromosome have

APA, Harvard, Vancouver, ISO, and other styles

49

VanHook, A. M. "Attract and Segregate." Science Signaling 5, no. 230 (2012): ec176-ec176. http://dx.doi.org/10.1126/scisignal.2003336.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Leonard, Madeleine. "Segregated Schools in Segregated Societies." Childhood 13, no. 4 (2006): 441–58. http://dx.doi.org/10.1177/0907568206068556.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!