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Dissertations / Theses on the topic 'Seizures febrile'

Author: Grafiati

Published: 4 June 2021

Last updated: 3 February 2022

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1

Tarkka, R. (Rita). "Pathogenesis, prevention of recurrences and outcome of febrile seizures." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514270886.

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Abstract Febrile seizures (FS) occur in 2-5% of children. Their pathogenesis is unknown. Elevated levels of prostaglandins (PG) have been found in cerebrospinal fluid after such seizures, and a third of all patients have recurrences. No safe ways of reducing the risk of recurrences have been found. The outcome has been shown in prospective studies to be good, by they have been linked to mesial temporal sclerosis (MTS) in patients with severe temporal lobe epilepsy (TLE). The aim was to analyze the records on the role of PGs in the pathogenesis of FS, to find risk factors for recurrences that

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2

Helvig, Ashley W. "Seizure and Behavioral Phenotyping of the Scn1a Mouse Model of Genetic Epilepsy with Febrile Seizures Plus." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/nursing_diss/32.

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Genetic epilepsy with febrile seizures plus (GEFS+) is associated with a wide range of neurological dysfunction caused in part by limited function in voltage-gated sodium channels (Escayg & Goldin, 2010; Gambardella & Marini, 2009; Mulley et al., 2005). The seizure and behavioral phenotypes, as well as use of non-pharmacologic agents as neuroprotectants in GEFS+, are not well-understood. An experimental design used an animal model of GEFS+ to 1. explore the effects of stress on seizure phenotype, 2. examine behavioral phenotypes, and 3. study the effects of an omega 3 fatty acid on abnormal

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3

Korngold, Caleb Bosler. "Febrile Infants and Common Respiratory Viruses: Epidemiology and Clinical Implications." Yale University, 2009. http://ymtdl.med.yale.edu/theses/available/etd-03062009-075645/.

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Fever in infants younger than 2 months of age causes a significant number of emergency department visits and is particularly worrisome because of the potential for serious infection. Management of febrile infants is problematic because clinical observation is not a reliable indicator of serious bacterial illness (SBI), such as bacteremia, meningitis, and urinary tract infection (UTI). Numerous investigators have proposed methods of screening laboratory tests to ascertain the risk of SBI in febrile infants. These screening tests could potentially avoid the invasive and costly sepsis work-up, wh

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4

Petersen, Anna, and Lena Åkesson. "Feberkramper hos barn - Sjuksköterskans preventiva arbete / Children with febrile seizures - The nurse’s preventive work." Thesis, Kristianstad University College, Department of Health Sciences, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-3753.

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<p>Background: Febrile seizures are common in childhood. When a child is stricken with febrile seizures it is not only the child that is suffering, in fact the whole family is affected. There are different ways to prevent recurrence of febrile seizures, such as use of different drugs. The parents also need information about febrile seizures and support from the nurse. Aim: The aim of this literature study was to illuminate the nurse’s preventive work for children who have been stricken with febrile seizures. Method: A literature search was conducted in different databases. A qualitative conten

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5

Kaur, Harsimrren. "The Role of Interleukin-1 in Febrile Seizures and Subsequent Onset of Temporal Lobe Epilepsy." Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.518458.

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6

Storz, Corinna [Verfasser], and Andrea Sylvia [Akademischer Betreuer] Winkler. "Neurological disorders in rural Tanzania : Characteristics of patients with febrile seizures and meningitis / Corinna Storz ; Betreuer: Andrea Sylvia Winkler." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1162840358/34.

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7

Khaled, Nathália Amato. "Estudo temporal integrado de redes de co-expressão gênica e microRNAs em um modelo experimental de convulsão febril induzida por hipertermia." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-13022019-151025/.

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As convulsões febris complexas durante a infância representam um fator de risco relevante para o desenvolvimento da epilepsia. Apesar desse fato, as alterações moleculares induzidas por essas crises febris, que tornam o cérebro susceptível ao processo de epileptogênese, ainda são pouco conhecidas. Nesse contexto, a utilização de modelos animais de crises febris induzidas por hipertermia (HS) permite o estudo das alterações moleculares a partir de uma análise temporal desse processo. Assim, neste trabalho foram investigadas as alterações temporais nos perfis de microRNAs e de expressão gênica e

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8

Azevedo, Hátylas Felype Zaneti de. "Alterações transcriptômicas no hipocampo de ratos submetidos a um modelo experimental de epilepsia com insulto precipitante febril." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-06062017-092009/.

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Convulsões febris complexas durante a infância representam um fator de risco importante para o desenvolvimento da epilepsia. Porém, pouco se sabe sobre as alterações moleculares induzidas por crises febris que tornam o cérebro susceptível à atividade epiléptica. Nesse contexto, modelos experimentais de convulsões induzidas por hipertermia (CH) permitem a análise temporal das alterações moleculares no cérebro após CH. Neste projeto, foram investigadas alterações temporais em redes de co-expressão gênica hipocampais durante o desenvolvimento de ratos Wistar submetidos a CH. Amostras de RNA foram

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9

Hamelin, Sophie. "Crises fébriles et syndrome d'épilepsie mésio-temporale. Une modélisation chez la souris de la théorie du double choc." Phd thesis, Université de Grenoble, 2012. http://tel.archives-ouvertes.fr/tel-00769920.

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Les crises fébriles représentent l'évènement épileptique le plus fréquent dans l'espèce humaine et touchent 5 % de la population. Bien que la bénignité de leur pronostic ait été établie par de nombreuses études prospectives, une infime proportion de ces enfants va développer un syndrome d'épilepsie mésio-temporale avec sclérose de l'hippocampe. L'hypothèse de ce travail est que la crise fébrile serait nécessaire mais non suffisante au développement de ce type d'épilepsie, un second élément au potentiel épileptogène serait ainsi indispensable. Notre travail a montré que les crises hyperthermiqu

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10

Guedj, Romain. "Risque d'urgence neurologique grave et curable parmi les enfants présentant une crise d'épilepsie en contexte fébrile : un exemple d'utilisation des dossiers médicaux informatisés des urgences pour la recherche clinique." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066005/document.

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Entre 2 et 5% des enfants de 6 mois à 5 ans présentent au moins un épisode de Crise d’Épilepsie en contexte Fébrile (CEF). Bien que généralement bénignes, ces crises sont associées à un risque d’urgences neurologiques graves et curables dont l’élimination requiert la réalisation d’examens complémentaires douloureux et/ou irradiants. Actuellement, ce risque est évalué en fonction de trois facteurs : l’âge de l’enfant, le caractère simple ou complexe de la crise, et l’examen clinique.Cette thèse avait pour objectif de tester l’hypothèse que parmi les enfants consultant pour une CEF, seuls ceux a

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11

Carvalho, Pedro Miguel Rocha. "Convulsões em crianças no contexto de utilização da vacina contra o Rotavirus." Master's thesis, 2017. http://hdl.handle.net/10316/82342.

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Trabalho de Projeto do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução e objetivo: Foi descrita uma associação entre a utilização da vacina contra o rotavírus (RV) e a redução da taxa de convulsões no seu global e de convulsões febris em particular, em crianças até dois anos após vacinação. Neste estudo pretendemos avaliar a evolução das taxas de admissão por convulsão num Serviço de Urgência (SU) em Portugal, país em que as vacinas contra RV são utilizadas no mercado privado desde 2006, com uma cobertura estimada que subiu de 16 para 44% entre 2007 e 2014. Um

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12

Sheppard, Emilie. "The impact of early life seizures on cognitive development." Thèse, 2019. http://hdl.handle.net/1866/21769.

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13

Awad, Patricia Nora. "Role of the cotransporter KCC2 in cortical excitatory synapse development and febrile seizure susceptibility." Thèse, 2015. http://hdl.handle.net/1866/13979.

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Le co-transporteur KCC2 spécifique au potassium et chlore a pour rôle principal de réduire la concentration intracellulaire de chlore, entraînant l’hyperpolarisation des courants GABAergic l’autorisant ainsi à devenir inhibiteur dans le cerveau mature. De plus, il est aussi impliqué dans le développement des synapses excitatrices, nommées aussi les épines dendritiques. Le but de notre projet est d’étudier l’effet des modifications concernant l'expression et la fonction de KCC2 dans le cortex du cerveau en développement dans un contexte de convulsions précoces. Les convulsions fébriles affect

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14

Thébault-Dagher, Fanny. "Le stress chez les enfants avec convulsions fébriles : mécanismes et contribution au pronostic." Thesis, 2019. http://hdl.handle.net/1866/24827.

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Le stress est continuellement associé à la genèse, la fréquence et la sévérité des convulsions en épilepsie. De nombreux modèles animaux suggèrent qu’une relation entre le stress et les convulsions soit mise en place en début de vie, voire dès la période prénatale. Or, il existe peu de preuves de cette hypothèse chez l’humain. Ainsi, l’objectif général de cette thèse était d’examiner le lien entre le stress en début de vie, dès la conception, et les convulsions chez les humains. Pour ce faire, cette thèse avait comme intérêt principal les convulsions fébriles (CF). Il s’agit de convulsions péd

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15

Shaker, Tarek. "Crosstalk between the immune and nervous systems : how early-life activation of toll-like receptors can alter hippocampal neuronal excitability and predisposition to seizures in rodents." Thesis, 2019. http://hdl.handle.net/1866/24590.

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Les récepteurs de type Toll (TLR) sont des récepteurs cellulaires jouant un rôle pivot dans le déclenchement de la réponse immunitaire après une infection ou une blessure, c'est-à-dire une inflammation. L'activation de la signalisation TLR a été associée à l’épilepsie. Dans ce projet, j'utilisai trois modèles distincts pour étudier comment le déclenchement des TLR contribue à l'épileptogenèse. Il existe une corrélation entre les malformations corticales développementales telle la dysplasie corticale focale (FCD) et convulsions fébriles dans les enfants de bas âge. Récemment, une réponse neuro-

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16

Prévost, François. "Développement physiologique des voies visuelles chez le rat normal et chez celui ayant subi des convulsions hyperthermiques." Thèse, 2011. http://hdl.handle.net/1866/4861.

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Les neurones des couches superficielles du collicule supérieur et du cortex visuel primaire du rat adulte sont sensibles à de basses fréquences spatiales de haut contraste défilant à des vitesses élevées. Entre les jours post-nataux 27-30 et l’âge adulte, les fréquences temporelles optimales des neurones du cortex visuel primaire augmentent, tandis que leurs seuils de contraste diminuent. Cependant, les fréquences spatiales optimales, les valeurs de résolution spatiale et les bandes passantes spatiales de ces neurones sont, dès l’ouverture des paupières, similaires à celles observées chez le r

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17

Lin, Chin-Chan, та 林志展. "Studies on the Role of Nitric Oxide in IL-1β-induced Febrile Seizure in Neonatal Rats". Thesis, 2004. http://ndltd.ncl.edu.tw/handle/13277642523974080875.

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碩士<br>嘉南藥理科技大學<br>生物科技研究所<br>92<br>Febrile seizure or febrile convulsion, an event induced by fever, is the most prevalent age-specific form of seizure in infants and young children, and usually occurs between the ages of 3 months to 5 years. The recurrence rate is about 30% and approximately 2-3% of suffering children are likely to become epilepsy in the future. However, febrile seizures result in immediate or latent sequelae such as hippocampal neuronal loss and temporal lobe epilepsy is still a subject of controversy. This study provides a new animal model of febrile seizures using the infa

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18

Babane, Constance Vusiwana. "Children's experience of epilepsy : a case study." Diss., 2002. http://hdl.handle.net/10500/1523.

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This study focuses on the way in which learners living with epilepsy, who attend mainstream schools in the rural areas of the Limpopo Province, experience epilepsy. The results of the study indicate that the needs of learners with epilepsy are not well-catered for in mainstream schools. They often experience fear, anxiety, humiliation, ostracisation, name-calling, scape-goating, blaming and suspicion. Recommendations were made regarding the measures which should be taken to address the needs of rural children living with epilepsy. These recommendations could be used by teachers

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