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Journal articles on the topic 'Selamectina'

Author: Grafiati

Published: 10 September 2021

Last updated: 17 July 2025

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1

Castro García, Leandro, and Manuel Saldivia Paredes. "Eficacia comparada de tres fármacos acaricidas utilizados en el tratamiento de otocariasis por Otodectes cynotis en gatos domésticos de Puerto Montt, región de Los Lagos, Chile." Revista de Medicina Veterinaria 1, no. 41 (2020): 91–105. http://dx.doi.org/10.19052/mv.vol1.iss41.9.

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Otodectes cynotis es uno de los ácaros responsables de causar dermatosis parasitaria en el pabellón auricular en animales de compañía, lo que les produce prurito intenso e incluso complicaciones óticas por falta del tratamiento adecuado. Su prevalencia en felinos domésticos puede llegar al 37 y el 85 % de los casos de otitis externa. Son variados los productos que pueden utilizarse para el tratamiento de este ácaro, aunque algunos no declaran en su etiquetado su uso en determinadas especies. Por otra parte, los datos disponibles sobre la eficacia comparada de los diversos fármacos utilizados s

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Vasconceslos, Jackson Suelio de, Marcos Wanderson Vieira Monteiro, Higor Vinícios da Silva Camelo, Lidia Stefânia Vilela Medeiros, Luana Maria Feitosa Barroso, and Sandra Batista Santos. "Aspectos Clínicos, Epidemiológicos e Terapêuticos da Sarna Sarcóptica Diagnosticada em Felinos Domésticos na Região Metropolitana de João Pessoa, Paraíba, Brasil." Research, Society and Development 11, no. 7 (2022): e22211729753. http://dx.doi.org/10.33448/rsd-v11i7.29753.

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As dermatopatias representam cerca de 30% dos atendimentos realizados na rotina clínica de pequenos animais. Dentre as dermatopatias parasitárias, a escabiose representa 7,3% dos casos, sendo caracterizada por intenso prurido, descamação, eritema, erupções cutâneas e lesões crostosas; também é uma doença de alta relevância pelo alto potencial zoonótico. O presente trabalho objetivou relatar os aspectos clínicos, epidemiológicos e terapêuticos da sarna sarcóptica em felinos diagnosticada na região metropolitana de João Pessoa, Paraíba, Brasil. Os animais foram submetidos a exames clínicos, derm

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Ferraz, Alexsander, Carolina da Fonseca Sapin, Renata Fontes Ongaratto, et al. "Anaplasmosis in Domestic Feline (Felis cattus) on South of Brazil: a Case Report." Ensaios e Ciência C Biológicas Agrárias e da Saúde 26, no. 4 (2023): 398–401. http://dx.doi.org/10.17921/1415-6938.2022v26n4p398-401.

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Anaplasmose é uma hemoparasitose causada pelo Anaplasma platys, uma bactéria gram-negativa, intracelular obrigatória que parasita as plaquetas do hospedeiro. A infecção ocorre principalmente pela picada do carrapato Rhipicephalus sanguineus e os sinais clínicos, quando presentes, costumam ser inespecíficos, como anorexia, apatia, mucosas pálidas, hipertermia e linfonodos aumentados. Na análise do sangue, o principal achado é a trombocitopenia. Portanto, o objetivo deste trabalho foi descrever um caso de anaplasmose em felino doméstico no município de Pelotas no estado do Rio Grande do Sul, Bra

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Gois, Luiz Fernando Wolpert de, Letícia Costa Carvalho, Rayssa Dourado Fontenele, Cleanto Luiz Maia Silva, Simone Mousinho Freire, and Luanna Soares de Melo Evangelista. "Ocorrência de piolhos Neopsittaconirmus spp. (Phthiraptera: Ischnocera: Philopteridae) em calopsita (Nymphicus hollandicus) no nordeste brasileiro." Medicina Veterinária (UFRPE) 16, no. 2 (2022): 81–87. http://dx.doi.org/10.26605/medvet-v16n2-4995.

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Piolhos mastigadores são normalmente encontrados em aves e mamíferos. Esses insetos são divididos em duas subordens de importância nas aves, a Amblycera e a Ischnocera, sendo que nesta última apenas a família Philopteridae abrange os piolhos específicos desses animais. Possuem as peças bucais adaptadas à mastigação da pele e penas, e quando parasitam aves como as calopsitas (Nymphicus hollandicus) podem provocar diversas alterações dermatológicas, sistêmicas e até mesmo comportamentais. O objetivo deste estudo foi relatar o encontro de espécimes de piolhos do gênero Neopsittaconirmus infestand

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Penedo, Camila Cristina de Sá, Ruben Horn Vasconcelos, Windleyanne Gonçalves Amorim Bezerra, and Flávia Liparisi. "Surto de mixomatose em criação de coelhos no estado do Rio de Janeiro: relato de caso." Medicina Veterinária (UFRPE) 17, no. 4 (2023): 203–9. http://dx.doi.org/10.26605/medvet-v17n4-5843.

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Objetivou-se com este trabalho relatar um surto de mixomatose em uma criação de coelhos na região rural do município de Cachoeiras de Macacu no estado do Rio de Janeiro. De um total de 103 coelhos, 8 óbitos ocorreram pela doença e 51 indivíduos foram eutanasiados com sinais clínicos típicos. Os animais apresentaram blefaroconjuntivite bilateral com secreção purulenta, progredindo para rinite com secreção sanguinolenta, edema de face e surgimento de pequenos nódulos na face, orelha e escroto. À necropsia, foram observados linfonodomegalia, esplenomegalia, pulmões congestos e edema escrotal. Nes

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Pereira, Paulo Douglas Gomes, Lucas Alencar Fernandes Beserra, Mateus Linhares de Almeida Mariz, et al. "INFESTAÇÃO POR Felicola subrostratus EM FELINO: RELATO DE CASO." Revista de Agroecologia no Semiárido 4, no. 4 (2020): 96. http://dx.doi.org/10.35512/ras.v4i4.4590.

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<p><em>Felicola subrostratus </em>é um ectoparasito específico de felinos de distribuição mundial e infestação incomum. São mastigadores, cuja infestação, geralmente, é observada na face, e na região dorsal. Em geral, os sintomas incluem inquietação, prurido com seborreia, alopecia, escoriações e infecções bacterianas secundárias. O diagnóstico da pediculose pode ser realizado através da visualização direta do piolho e microscopia. Para o tratamento, inclui-se a utilização de ivermectina, selamectina, Fipronil e inseticidas. O objetivo deste trabalho foi relatar um caso de in

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Folliero, Veronica, Federica Dell’Annunziata, Biagio Santella, et al. "Repurposing Selamectin as an Antimicrobial Drug against Hospital-Acquired Staphylococcus aureus Infections." Microorganisms 11, no. 9 (2023): 2242. http://dx.doi.org/10.3390/microorganisms11092242.

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The emergence of multidrug-resistant strains requires the urgent discovery of new antibacterial drugs. In this context, an antibacterial screening of a subset of anthelmintic avermectins against gram-positive and gram-negative strains was performed. Selamectin completely inhibited bacterial growth at 6.3 μg/mL concentrations against reference gram-positive strains, while no antibacterial activity was found against gram-negative strains up to the highest concentration tested of 50 μg/mL. Given its relevance as a community and hospital pathogen, further studies have been performed on selamectin

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8

Gunnarsson, Lotta, Dan Christensson, and Eleonor Palmér. "Clinical Efficacy of Selamectin in the Treatment of Naturally Acquired Infection of Sucking Lice (Linognathus setosus) in Dogs." Journal of the American Animal Hospital Association 41, no. 6 (2005): 388–94. http://dx.doi.org/10.5326/0410388.

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A clinical study was performed in 21 dogs to evaluate the efficacy of selamectin for the treatment of naturally acquired infection of sucking lice (Linognathus setosus [L.setosus]) in dogs. Each dog was randomly assigned to one of two treatment groups. One group was treated with selamectin applied topically at a mean dosage of 7.9 mg/kg. The other group was treated with permethrin applied topically at a mean dosage of 85.7 mg/kg. At day 42 posttreatment, all animals remaining in the study (10 treated with selamectin and six with permethrin) were clear of lice. In both groups, the reduction in

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Ezquerra-Aznárez, José Manuel, Giulia Degiacomi, Henrich Gašparovič, et al. "The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme." International Journal of Molecular Sciences 23, no. 2 (2022): 771. http://dx.doi.org/10.3390/ijms23020771.

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Avermectins are macrocyclic lactones with anthelmintic activity. Recently, they were found to be effective against Mycobacterium tuberculosis, which accounts for one third of the worldwide deaths from antimicrobial resistance. However, their anti-mycobacterial mode of action remains to be elucidated. The activity of selamectin was determined against a panel of M. tuberculosis mutants. Two strains carrying mutations in DprE1, the decaprenylphosphoryl-β-D-ribose oxidase involved in the synthesis of mycobacterial arabinogalactan, were more susceptible to selamectin. Biochemical assays against the

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Jain, Supnesh, Ranbir Singh Jatav, Rupesh Verma, et al. "Antiparasitic Efficacy in Canine Sarcoptic Mange: A Comparison Study." Journal of Advances in Biology & Biotechnology 28, no. 1 (2025): 728–37. https://doi.org/10.9734/jabb/2025/v28i11928.

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Sarcoptic mange, caused by Sarcoptes scabiei var. canis, is a highly contagious and zoonotic ectoparasitic infestation affecting dogs worldwide. This study evaluated the occurrence of sarcoptic mange and compared the therapeutic efficacy of selamectin, sarolaner and ivermectin in affected dogs in and around Jabalpur, Madhya Pradesh, India. From May to October 2024, 269 dogs with dermatological affections suspected of sarcoptic mange were examined, with 13 dogs (4.83%) tested positive based on skin scrapings. Age-wise analysis revealed that young dogs (<1 year) exhibited a higher susceptibil

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11

Jacsó, Olga, Éva Fok, Gabriella Kiss, Gábor Kökény, and Zsolt Lang. "Preliminary findings on the efficacy of selamectin in the treatment of dogs naturally infected with Dirofilaria repens." Acta Veterinaria Hungarica 58, no. 4 (2010): 405–12. http://dx.doi.org/10.1556/avet.58.2010.4.1.

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Subcutaneous dirofilariosis caused by Dirofilaria repens is common in dogs and it is an emerging helminthozoonosis in Europe, Asia, Africa and also in Hungary. Macrocyclic lactones are used for preventing the infection; however, their activity against the microfilariae and mature stages of this species is questionable. Selamectin is widely used for the prophylaxis of heartworm ( D. immitis ) infection. The objective of the present study was to test the microfilaricidal efficacy of the topical formulation of selamectin in dogs naturally infected with D. repens . A total of 78 Beagle dogs were e

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12

DiGeronimo, Peter M. "Therapeutic Review: Selamectin." Journal of Exotic Pet Medicine 25, no. 1 (2016): 80–83. http://dx.doi.org/10.1053/j.jepm.2015.11.001.

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13

Tsokana, Constantina N., George Valiakos, Kennedy Mwacalimba, et al. "A Discrete Choice Experiment to Assess Cat Owners’ Preferences for Topical Antiparasitics and the Comparative Ease of Use of a Combined Selamectin and Sarolaner Formulation: An International Survey." Animals 15, no. 13 (2025): 1985. https://doi.org/10.3390/ani15131985.

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Cat owners are involved in their cats’ healthcare, including the prevention of parasitic diseases. However, a comprehensive understanding of their preferences for feline antiparasitics is lacking. This study addresses this gap through a multifaceted methodology comprising three phases. In Phase 1, the physical properties and usability aspects of seven topical antiparasitic formulations were assessed. Within Phase 2, an ease-of-use study was conducted to evaluate the cat owners’ application experience with deidentified products representing three topical antiparasitics. Phase 3 included the ide

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Rudik, Irina, Margie R. Cummings, and Robert H. Poppenga. "Isolation and Multiresidue Detection of Macrolide Endectocides Present in Animal Matrices." Journal of Veterinary Diagnostic Investigation 14, no. 4 (2002): 295–302. http://dx.doi.org/10.1177/104063870201400404.

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A simple, rapid, and sensitive method for isolation and detection of macrolide endectocides (moxidectin, doramectin, selamectin, ivermectin, and eprinomectin) in animal sera and liver is described. Fortified sera or homogenized liver samples were treated with sodium chloride followed by organic solvent extraction. No additional steps were required prior to analysis. Separation of analytes and collection of mass information was achieved by liquid chromatography/mass spectrometry with positive atmospheric pressure chemical ionization set in selected ion monitoring mode with each sample analysis

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Hermawan, Intan, Kurnia Desiandura, and Hana Cipka Pramuda Wardhani. "Ivermectin Versus Selamectin and Fipronil as Ectoparasite Treatment in Cats and Dogs: A Literature Review." Media Kedokteran Hewan 35, no. 2 (2024): 179–96. http://dx.doi.org/10.20473/mkh.v35i2.2024.179-196.

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Ectoparasite is commonly found on the skin and can cause dermatological problems. In veterinary practices, ivermectin, selamectin, and fipronil are commonly used to treat ectoparasitosis. This article aims to deeply examines the indications and contraindications of ivermectin, selamectin and fipronil. Ectoparasites are commonly found in cats and dogs and make up a large percentage of cases compared to other diseases. Therefore, it is important to have an understanding of the drugs that are effective against ectoparasites. In the past, ivermectin was a popular antiparasitic drug due to its high

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Kadyrova, D. V. "Acute toxicity of antiparasitic selamectin-based drug." Russian Journal of Parasitology 18, no. 3 (2024): 292–300. http://dx.doi.org/10.31016/1998-8435-2024-18-3-292-300.

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The purpose of the research is to evaluate some toxicological parameters of antiparasitic selamectin-based drug.Materials and methods. The study drug is a solution for external use, 1 mL of which contains the active component selamectin (120 mg), as well as additives. The experiments used a total of 66 white outbred male rats, 42 white outbred male mice and 3 guinea pigs. The parameters of acute oral toxicity (in mice and rats), acute dermal toxicity (in rats), and dermal and mucous membrane irritation (in rats and guinea pigs) of antiparasitic selamectin-based drug were evaluated. LD50 was ca

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Gunnarsson, Lotta, Göran Zakrisson, Dan Christensson, and Arvid Uggla. "Efficacy of Selamectin in the Treatment of Nasal Mite (Pneumonyssoides caninum) Infection in Dogs." Journal of the American Animal Hospital Association 40, no. 5 (2004): 400–404. http://dx.doi.org/10.5326/0400400.

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In a laboratory study to evaluate the efficacy of selamectin for treatment of canine nasal mite infection, 12 purpose-bred beagles were experimentally infected with Pneumonyssoides caninum (P. caninum). Six of the dogs were treated with selamectin applied to the skin of the back at dosages of 6 to 24 mg/kg for three times at 2-week intervals. The remaining six dogs were an untreated control group. At necropsy 39 to 46 days after inoculation, no P. caninum mites were found in any of the treated dogs. In contrast, nasal mites were found in five of the untreated dogs. This difference was statisti

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Lee-Fowler, Tekla M., Robert C. Cole, A. Ray Dillon, Shannon Graham, D. Michael Tillson, and Sharron Barney. "High-resolution CT evaluation of bronchial lumen to vertebral body, pulmonary artery to vertebral body and bronchial lumen to pulmonary artery ratios in Dirofilaria immitis-infected cats with and without selamectin administration." Journal of Feline Medicine and Surgery 20, no. 10 (2017): 928–33. http://dx.doi.org/10.1177/1098612x17734999.

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Objectives The bronchial lumen to pulmonary artery (BA) ratio is utilized to evaluate pulmonary pathology on CT images. The BA ratio may be unreliable when changes are present in bronchial and pulmonary arteries concurrently. Bronchial lumen to vertebral body (BV) and pulmonary artery to vertebral body (AV) ratios have been established in normal cats and may serve as an alternative. This study aimed to evaluate the BV, AV and BA ratios in cats before and after infection with Dirofilaria immitis, with and without selamectin administration, and to characterize the distribution of disease. Method

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Novotny, M. J., M. J. Krautmann, J. C. Ehrhart, et al. "Safety of selamectin in dogs." Veterinary Parasitology 91, no. 3-4 (2000): 377–91. http://dx.doi.org/10.1016/s0304-4017(00)00306-x.

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Krautmann, M. J., M. J. Novotny, K. De Keulenaer, et al. "Safety of selamectin in cats." Veterinary Parasitology 91, no. 3-4 (2000): 393–403. http://dx.doi.org/10.1016/s0304-4017(00)00307-1.

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ÖZKÖK, Arda Onur. "Effect of Bird Mite on Reproduction in Gloster Canaries and Treatment." MAS Journal of Applied Sciences 8, no. 2 (2023): 356–61. https://doi.org/10.5281/zenodo.8023224.

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Dermanyssus Gallinae  pose a serious danger to birds. The biggest problem for the breeder in cage birds is the breeding time. Stressed male birds have low libido as well as low semen yield.  Although there are many options to be applied in the treatment, frequent repetition of the application affects the birds negatively. Carbamate insecticides used in the production season can pass into the eggs. Mite infestation was detected in 15 canaries with constant itching and restlessness during the breeding season. 2 weeks after the application of Selamectin, a serious decrease was observed

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Gupta, R. C., M. B. Masthay, T. D. Canerdy, et al. "Human Exposure to Selamectin from Dogs Treated with Revolution™: Methodological Consideration for Selamectin Isolation." Toxicology Mechanisms and Methods 15, no. 4 (2005): 317–21. http://dx.doi.org/10.1080/15376520590968860.

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23

Moonarmart, Walasinee, Mookmanee Tansakul, Chatkamol Kiewsiri, et al. "Haematological response in the treatment of naturally acquired ectoparasite infestations in rabbits." World Rabbit Science 26, no. 4 (2018): 313. http://dx.doi.org/10.4995/wrs.2018.9823.

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The objective of this study was to determine changes in haematological values of topical administration of selamectin in rabbits with at least one species of naturally acquired ectoparasite infestation (<em>Sarcoptes scabiei</em> var. <em>cuniculi</em>, <em>Psoroptes cuniculi</em>, or <em>Cheyletiella</em> spp). Thirty-five rabbits were enrolled. They underwent physical examination and assessment of ectoparasite infestations on days 0, 14, 28, 56 and 86. Blood for haematology and serum biochemistry was collected on days 0, 14, 28 and 56. Selamect

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Makhvatova. "STUDY OF EFFICIENCY OF APPLICATION OF THE PRODUCT BASED ON SELAMECTIN IN ECTOPARASITOSIS OF DOGS AND CATS." THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL, no. 21 (May 29, 2020): 229–33. http://dx.doi.org/10.31016/978-5-9902341-5-4.2020.21.229-233.

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Ectoparasites of carnivores (dogs and cats) are ubiquitous and cause irreversible pathological processes, worsen the general health of animals, aggravate the course of chronic diseases, reduce immunity and can even lead to the death of dogs and cats, especially at an early age [5, 6]. Despite the significant achievements and successes of veterinary medicine in the elimination of ectoparasites, the problem of treatment and prevention of parasitic diseases of domestic dogs and cats remains an urgent task today. The drugs used for parasitic diseases of carnivores are subject to rather high requir

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Wrieg, H. H., W. Beck, and A. Conrads. "Ohrräude durch Otodectes cynotis bei der Katze – Erregerbiologie, Pathogenese, Klinik, Diagnose und Therapie mit Selamectin (Stronghold®)." Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere 34, no. 02 (2006): 112–17. http://dx.doi.org/10.1055/s-0037-1622517.

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Zusammenfassung Gegenstand und Ziel: Die Ohrräude, verursacht durch Otodectes cynotis (Hering, 1858), ist eine sehr häufige Erkrankung des äußeren Gehörgangs bei Katzen. Otodectes cynotis kann als verbreitetste Räudemilbe bei Fleischfressern angesehen werden. Zur Behandlung lassen sich verschiedene Antiparasitika einsetzen. Ziel der vorliegenden Wirksamkeitsstudie war die Evaluierung von Selamectin (Stronghold® Spot-on) bei der Tilgung von Ohrräudemilben bei der Katze unter Feldbedingungen. Material und Methoden: 16 Katzen mit Ohrmilbenbefall (Otodectes cynotis), die in der regulären tierärztl

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Kumar, Kamalu S., Ambily VR, and Usha Narayana Pillai. "Therapeutic efficacy of topical selamectin in feline otoacariosis." Journal of Entomology and Zoology Studies 9, no. 4 (2021): 346–47. http://dx.doi.org/10.22271/j.ento.2021.v9.i4e.8793.

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Robinson, Natalie, and Marnie Brennan. "Selamectin versus ivermectin for cheyletiellosis in pet rabbits." Veterinary Record 178, no. 14 (2016): 344–45. http://dx.doi.org/10.1136/vr.i1387.

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E. Jacobs, Dennis. "Selamectin — a novel endectocide for dogs and cats." Veterinary Parasitology 91, no. 3-4 (2000): 161–62. http://dx.doi.org/10.1016/s0304-4017(00)00288-0.

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Dupuy, J., A. L. Derlon, J. F. Sutra, M. C. Cadiergues, M. Franc, and M. Alvinerie. "Pharmacokinetics of Selamectin in Dogs after Topical Application." Veterinary Research Communications 28, no. 5 (2004): 407–13. http://dx.doi.org/10.1023/b:verc.0000034993.87007.f8.

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Chable-Bessia, Christine, Charlotte Boullé, Aymeric Neyret, et al. "Low Selectivity Indices of Ivermectin and Macrocyclic Lactones on SARS-CoV-2 Replication In Vitro." COVID 2, no. 1 (2022): 60–75. http://dx.doi.org/10.3390/covid2010005.

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Ivermectin was first approved for human use as an endectocide in the 1980s. It remains one of the most important global health medicines in history and has recently been shown to exert in vitro activity against SARS-CoV-2. However, the macrocyclic lactone family of compounds has not previously been evaluated for activity against SARS-CoV-2. The present study aims at comparing their anti-viral activity in relevant human pulmonary cell lines in vitro. Here, in vitro antiviral activity of the avermectins (ivermectin and selamectin) and milbemycins (moxidectin and milbemycin oxime) were assessed a

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Cadiergues, M. C., C. Caubet, and M. Franc. "Comparison of the activity of selamectin, imidacloprid and fipronil for the treatment of dogs infested experimentally with Ctenocephalldes canis and Ctenocephalides felis felis." Veterinary Record 149, no. 23 (2001): 704–6. http://dx.doi.org/10.1136/vr.149.23.704.

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Twenty-four beagles were randomly allocated into four groups of six and housed in separate cages. Each dog was infested with 25 Ctenocephalides canis and 25 Ctenocephalides felis felis and two days later (day 0) the dogs in groups 1, 2 and 3 received a spot-on application of selamectin (6 mg/kg), imidacloprid (10 mg/kg), or fipronil (6.7 mg/kg), respectively, while the dogs in group 4 were not treated. The dogs were combed 48 hours later, the fleas were removed, counted and their species were determined. All the dogs were reinfested with the same number of the two species of fleas on days 7,14

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CĂTANĂ, Laura, Raul CĂTANĂ, Roxana CORA, Ştefan RĂILEANU, and Mihai CERNEA. "In Vitro Study of Benzimidazole Derivatives, Tetrahydropyrimidines and Macrocyclic Lactones Therapeutic Efficacy in Dog Hookworms." Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine 75, no. 2 (2018): 199. http://dx.doi.org/10.15835/buasvmcn-vm:2018.0019.

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The study was conducted using faecal samples from 62 dogs. We tested the ovicidal and larvicidal effects of albendazole (ABZ), mebendazole (MBZ), fenbendazole (FBZ) and flubendazole (FLU) by Egg hatch assay (EHA) and larval development assay (LDA). For pyrantel (PYR) and selamectin (SEL) we tested the larvicidal effects by LDA. In all in vitro tests, benzimidazoles efficacy was low, with a high risk of inducing resistance phenomena. In EHA more than 50% of the hookworm eggs hatched, revealing a low efficacy of all tested benzimidazoles. The regression line was positive for all benzimidazoles,

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Granados-Tristán, Ana Laura, Mauricio Carrillo-Tripp, Carlos Eduardo Hernández-Luna, et al. "Mycobacterium susceptibility to ivermectin by inhibition of eccD3, an ESX-3 secretion system component." PLOS Computational Biology 21, no. 4 (2025): e1012936. https://doi.org/10.1371/journal.pcbi.1012936.

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Drug-resistant tuberculosis is a pressing global health issue that requires the development of new drugs or the identification of new therapeutic targets. The ESX-3 secretion system is essential for the Mycobacterium tuberculosis growth and plays a role in iron/zinc homeostasis and virulence. The aim of this study was to evaluate the quaternary interface of EccD3, a component of the ESX-3 secretion system, and to evaluate the association of an eccD3 mutant with drug resistance. The molecular structures of EccD3 protein and other ESX-3 secretion system proteins of the M. tuberculosis were predi

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Luca, Iasmina, and Yagoob Garedaghi. "The Use of Selamectin in Treating Notoedric Mange in Cats: A Case Report." International Journal of Medical Parasitology and Epidemiology Sciences 2, no. 3 (2021): 77–78. http://dx.doi.org/10.34172/ijmpes.2021.21.

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Notoedric mange in cats is less commonly diagnosed compared to sarcoptic mange. In the present study, a 9-month-old tomcat with severe itching, alopecia, crusts, and ulcerative necrotic areas on the head and neck underwent a clinical examination. The laboratory tests (superficial scrapes of the skin) confirmed the presence of Notoedres mites. The topical administration of 2 doses of 45 mg selamectin, 14 days apart, resulted in the complete healing of the animal.

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Petrov, R. V., and O. V. Derevianchenko. "Determination of the therapeutic effectiveness of the drug against siphonaptero-sis of cats based on selamectin and praziquantel." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 26, no. 116 (2024): 79–82. https://doi.org/10.32718/nvlvet11611.

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One of the common diseases of cats is siphonapterosis, a disease caused by fleas. Sustained effectiveness of the drug against fleas and suppression of flea egg production is necessary to ensure optimal control. The article presents data on determining the therapeutic effectiveness against siphonapterosis of cats based on selamectin and praziquantel. The purpose of our research was to determine the therapeutic effectiveness of the new drug “Selgrad” and to compare the hematological indicators of sick cats before and after treatment with the specified drug. The drug “Selgrad” was used for the ex

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Ozkan, Cumali, Mehmet Karaca, and Nalan Ozdal. "Topical Selamectin Treatment of Otodectes cynotis in Van Cats." Turkish Journal of Parasitology 37, no. 4 (2014): 269–72. http://dx.doi.org/10.5152/tpd.2013.3123.

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Schnabl, B., S. Bettenay, N. Glos, M. Linek, C. Loewenstein, and R. S. Mueller. "Oral selamectin in the treatment of canine generalised demodicosis." Veterinary Record 166, no. 23 (2010): 710–14. http://dx.doi.org/10.1136/vr.4850.

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Senthil, Keerthika, Abiramy Prabavathy Arumugam, Vijayalakshmi Padmanaban, Devadevi Narayanan, and Rajkumar Karuppaiah. "Selamectin Spot-on: A Cure for Scabies in Rabbits." Small Animal Advances 2, no. 2 (2023): 26–28. http://dx.doi.org/10.58803/saa.v2i2.12.

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Introduction: Mange in rabbits is a highly contagious zoonotic disease. The disease is caused mainly by Sarcoptes scabiei, Psoroptes cuniculi, Cheyletiella parasitovorax, and Notoedres cati. The most common forms of this disease in rabbits are body and ear mange. Mites infest animals through direct contact with infected animals or contaminated. Case report: An 8-month-old non-descript female rabbit weighing about 700 g was presented to the Teaching Veterinary clinical complex, Mettupalayam, Puducherry, India, with a history of scratching, pruritus and dried crusty lesions on the margins of the

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Simpson, Andrew C. "Successful treatment of otodemodicosis due to Demodex cati with sarolaner/selamectin topical solution in a cat." Journal of Feline Medicine and Surgery Open Reports 7, no. 1 (2021): 205511692098438. http://dx.doi.org/10.1177/2055116920984386.

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Case summary A 10-year-old spayed female Russian Blue cat was presented with a 3-month history of excessive otic discharge and scratching, only involving the right ear. Other than a moderate amount of ceruminous exudate present within the right ear on video-otoscopic examination, there were no other cutaneous abnormalities. The cat was deemed to be otherwise in good health based on physical examination and several laboratory profiles. A diagnosis of otodemodicosis was determined due to the presence of a large number of Demodex cati mites retrieved from cerumen. Treatment consisted only of mont

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Klinger, Christoph J., Teresa M. S. A. Boehm, Marco Roller, and Tobias Knauf-Witzens. "Morphological diagnosis and successful treatment of chorioptic mange in 2 South American coatis (Nasua nasua)." Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere 49, no. 06 (2021): 432–35. http://dx.doi.org/10.1055/a-1585-7532.

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AbstractTwo female South American coatis (Nasua nasua) kept in a zoo in Southern Germany presented with pruritus and moderate hair loss at the dorsal trunk, thigh areas and alongside the tail. Otherwise the animals showed no clinical signs. While the clinical general examination as well as cytology of dermatologic samples showed no pathologic changes, Chorioptes sp. mites could be identified in a superficial skin scraping. Two consecutive topical applications of a selamectin/sarolaner spot-on formulation 4 weeks apart lead to a complete resolution. No side effects were observed.

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Chuan, Yu, Liu Penggang, Yang Gang, and Wu Qiang. "The Pharmacokinetics and Skin Changes in Rabbit on Selamectin Solution." International Journal of Animal Science and Technology 5, no. 2 (2021): 32. http://dx.doi.org/10.11648/j.ijast.20210502.11.

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SOTIRAKI (Σ. ΣΩΤΗΡΑΚΗ), S., C. HIMONAS (Χ. ΧΕΙΜΩΝΑΣ), P. DEBOUCK, and G. BITSAS (Γ. ΜΠΙΤΖΑΣ). "Efficacy and safety of selamectin of flea infestation in dags." Journal of the Hellenic Veterinary Medical Society 53, no. 1 (2018): 78. http://dx.doi.org/10.12681/jhvms.15362.

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The study was conducted at three dog shekers in Thessaloniki Greece, το confirm die efficacy and safety of selamectin aτ a minimum dosage of 6 mg/kg adminisτered topically as a monthly dose repeaτed three times in die treatment of natural i n f l a t i o n s of Ctenocephalides spp. Twenty (20) dogs, with confirmed naturally acquired flea inflations, were enrolled in die sttidy as primary patiems. All animals completed the study on day 90. Twenty-two in cornai dogs were also treated but not evaluated for efficacy (secondary patiems). There was no untreated group. Only one live adult flea was re

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Bishop, B. F., C. I. Bruce, N. A. Evans, et al. "Selamectin: a novel broad-spectrum endectocide for dogs and cats." Veterinary Parasitology 91, no. 3-4 (2000): 163–76. http://dx.doi.org/10.1016/s0304-4017(00)00289-2.

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Shanks, D. J., P. Gautier, T. L. McTier, N. A. Evans, G. Pengo, and T. G. Rowan. "Efficacy of selamectin against biting lice on dogs and cats." Veterinary Record 152, no. 8 (2003): 234–37. http://dx.doi.org/10.1136/vr.152.8.234.

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Emmerich, Ilka. "Neue Arzneimittel für Kleintiere 2017." Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere 46, no. 02 (2018): 99–104. http://dx.doi.org/10.15654/tpk-180334.

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ZusammenfassungIm Jahr 2017 kam für Kleintiere mit Lokivetmab (Cytopoint®), einem kaninisierten monoklonalen Antikörper gegen das Zytokin Interleukin 31, ein neuer Wirkstoff auf den deutschen Tierarzneimittelmarkt. Ein Wirkstoff erhielt eine Tierartenerweiterung. So wurde Sarolaner, ein Ektoparasitikum der Isoxazolingruppe, in Kombination mit Selamectin (Stronghold® Plus) auch für Katzen zugelassen. Das Testosteronderivat Nandrolon (Nandrosol®) und die Kombination aus dem Benzodiazepin Zolazepam mit dem “dissoziativen Anästhetikum” Tiletamin (Zoletil®) erhielten erneut eine Zulassung. Außerdem

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Iacob, Olimpia, and Adriana Iftinca. "The dermatitis by Caparinia tripilis and Microsporum , in african pygmy hedgehog (Atelerix albiventris) in Romania – first report." Revista Brasileira de Parasitologia Veterinária 27, no. 4 (2018): 584–88. http://dx.doi.org/10.1590/s1984-296120180053.

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Abstract Investigations were conducted on a case of generalized dermatitis in an African pygmy hedgehog (Atelerix albiventris), purchased as a pet. Clinical examination revealed restlessness, agitation, itching and scratching, large alopecic areas, skin congestion and thin whitish scabs. Five skin lesions were scraped and the samples were collected for laboratory tests. Microscopy revealed the presence of the mite Caparinia tripilis (Acari: Psoroptidae). A dermatophyte belonging to Microsporum genus was also isolated by culture on specific media. Selamectin spot-on and enilconazole washes were

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Hahn, Alicia, Jennifer D'Agostino, Gretchen Cole, and Butch Kukanich. "PHARMACOKINETICS OF SELAMECTIN IN HELMETED GUINEAFOWL (NUMIDA MELEAGRIS) AFTER TOPICAL ADMINISTRATION." Journal of Zoo and Wildlife Medicine 45, no. 1 (2014): 176–78. http://dx.doi.org/10.1638/2013-0112r.1.

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MURAOKA, Noboru, Naoyuki ITOH, Mikiko AOKI, and Tadashi ITAGAKI. "Treatment of Sarcoptes scabiei var. canis Infestation in Dogs with Selamectin." Journal of the Japan Veterinary Medical Association 59, no. 2 (2006): 131–33. http://dx.doi.org/10.12935/jvma1951.59.131.

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Blot, C., A. Kodjo, M. C. Reynaud, and G. Bourdoiseau. "Efficacy of selamectin administered topically in the treatment of feline otoacariosis." Veterinary Parasitology 112, no. 3 (2003): 241–47. http://dx.doi.org/10.1016/s0304-4017(02)00449-1.

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Beck, Wieland. "Treatment of Gouldian finches (Erythrura gouldiae) infested by Sternostoma tracheacolum with selamectin." Journal of Exotic Pet Medicine 34 (July 2020): 48. http://dx.doi.org/10.1053/j.jepm.2020.04.010.

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