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Relevant bibliographies by topics / Selective benzonitrile synthesis

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Journal articles

Academic literature on the topic 'Selective benzonitrile synthesis'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Selective benzonitrile synthesis"

1

Sun, Hong Bin, Wen Long Chen, Yuan Hua Sun, Peng Qin, and Xuan Qi. "InCl₃: an Airstable and Water-Tolerant Catalyst for the Selective Synthesis of 5-Aryl Tetrazole." Advanced Materials Research 396-398 (November 2011): 2416–19. http://dx.doi.org/10.4028/www.scientific.net/amr.396-398.2416.

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2

Mokhtary, Masoud, and Faranak Najafizadeh. "Polyvinylpolypyrrolidone-Supported Boron Trifluoride; Highly Efficient Catalyst for the Synthesis ofN-tert-Butyl Amides." E-Journal of Chemistry 9, no. 2 (2012): 576–82. http://dx.doi.org/10.1155/2012/632574.

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Highly efficient method for the preparation ofN-tert-butyl amides by reaction of nitriles withtert-butyl acetate is described using polyvinylpolypyrrolidone-supported boron trifluoride (PVPP-BF3) at 70°C in good to excellent yields. Selective amidation of benzonitrile in the presence of acetonitrile was also achieved. polyvinylpolypyrrolidone-boron trifluoride complex shows non-corrosive and stable solid catalyst elevated Lewis acid property.

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3

Krishna Reddy, Reddivari Chenna, Syed Rasheed, Devineni Subba Rao, Shaik Adam, Yellala Venkata Rami Reddy, and Chamarthi Naga Raju. "New Urea and Thiourea Derivatives of Piperazine Doped with Febuxostat: Synthesis and Evaluation of Anti-TMV and Antimicrobial Activities." Scientific World Journal 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/682603.

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A series of new 4-(5-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-2-carbonyl)-N-(substituted phenyl)piperazine-1-carboxamides8(a–e)/carbothioamides8(f–j)were accomplished for biological interest by the simple addition of active functionalized arylisocyanates7(a–e)/arylisothiocyanates7(f–j)with 2-isobutoxy-5-(4-methyl-2-(piperazine-1-carbonyl)thiazol-5-yl)benzonitrile(4). Compound4was synthesized in high yields (94%) by the condensation reaction of febuxostat (1) with piperazine using a selective reagent such as propylphosphonic anhydride (T3P). Antiviral activity againstTobacco mosaic virus(TM

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4

Möller, Tristan, Hui-Chung Wen, Nana Naumann, Oliver Krug, and Mario Thevis. "Identification and Synthesis of Selected In Vitro Generated Metabolites of the Novel Selective Androgen Receptor Modulator (SARM) 2f." Molecules 28, no. 14 (2023): 5541. http://dx.doi.org/10.3390/molecules28145541.

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Among anabolic agents, selective androgen receptor modulators (SARMs) represent a new class of potential drugs that can exhibit anabolic effects on muscle and bone with reduced side effects due to a tissue-selective mode of action. Besides possible medical applications, SARMs are used as performance-enhancing agents in sports. Therefore, they are prohibited by the World Anti-Doping Agency (WADA) in and out of competition. Since their inclusion into the WADA Prohibited List in 2008, there has been an increase in not only the number of adverse analytical findings, but also the total number of SA

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5

Asano, Moriteru, Takenori Hitaka, Takashi Imada, et al. "Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives." Bioorganic & Medicinal Chemistry Letters 27, no. 9 (2017): 1897–901. http://dx.doi.org/10.1016/j.bmcl.2017.03.038.

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6

Aikawa, Katsuji, Moriteru Asano, Koji Ono, et al. "Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate." Bioorganic & Medicinal Chemistry 25, no. 13 (2017): 3330–49. http://dx.doi.org/10.1016/j.bmc.2017.04.018.

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7

Mlakić, Milena, Tena Čadež, Goran Šinko, Irena Škorić, and Zrinka Kovarik. "New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics." Biomolecules 14, no. 6 (2024): 679. http://dx.doi.org/10.3390/biom14060679.

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New furan, thiophene, and triazole oximes were synthesized through several-step reaction paths to investigate their potential for the development of central nervous systems (CNS)-active and cholinesterase-targeted therapeutics in organophosphorus compound (OP) poisonings. Treating patients with acute OP poisoning is still a challenge despite the development of a large number of oxime compounds that should have the capacity to reactivate acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The activity of these two enzymes, crucial for neurotransmission, is blocked by OP, which has the

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8

Razali, Nurul, and James McGregor. "Improving Product Yield in the Direct Carboxylation of Glycerol with CO2 through the Tailored Selection of Dehydrating Agents." Catalysts 11, no. 1 (2021): 138. http://dx.doi.org/10.3390/catal11010138.

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Improved yields of, and selectivities to, value-added products synthesised from glycerol are shown to be achieved through the judicious selection of dehydrating agents and through the development of improved catalysts. The direct carboxylation of glycerol with CO2 over lanthanum-based catalysts can yield glycerol carbonate in the presence of basic species, or acetins in the presence of acidic molecules. The formation of glycerol carbonate is thermodynamically limited; removal of produced water shifts the chemical equilibrium to the product side. Acetonitrile, benzonitrile and adiponitrile have

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9

Wang, Le, Gary T. Wang, Xilu Wang, et al. "Design, Synthesis, and Biological Activity of 4-[(4-Cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles as Potent and Selective Farnesyltransferase Inhibitors." Journal of Medicinal Chemistry 47, no. 3 (2004): 612–26. http://dx.doi.org/10.1021/jm030434f.

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10

Moreland, Donald E. "Research on Biochemistry of Herbicides: An Historical Overview." Zeitschrift für Naturforschung C 48, no. 3-4 (1993): 121–31. http://dx.doi.org/10.1515/znc-1993-3-402.

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Abstract Otto Warburg, the father of cellular bioenergetics, seems to have been the first investigator to report on inhibition of a plant biochemical reaction by a progenitor of a selective herbicide. The year was 1920 and the compound was phenylurethane (ethyl N-phenylcarbam ate or EPC). Warburg found that it strongly inhibited photosynthesis in Chlorella. EPC did not develop into a commercial herbicide, but the isopropyl derivatives (propham and chlorpropham) which were introduced in the late 1940s became selective herbicides. The phenylureas (monuron and diuron) were introduced in the early

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