Academic literature on the topic 'Selective deprotection'

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Journal articles on the topic "Selective deprotection"

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Brindaban, C. Ranu, K. Guchhait Sankar, and Saha Manika. "A convenient and efficient procedure for selective deprotection of acetates by titanium(IV) isopropoxide." Journal of Indian Chemical Society Vol. 76, Nov-Dec 1999 (1999): 547–49. https://doi.org/10.5281/zenodo.5862033.

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Department of Organic Chemistry, Indian Association for the Cultivation of Science, Calcutta-700 032, India <em>Manuscript received 6 August 1999</em> A simple and efficient procedure for the deprotection of acetates using titanium(lV) isopropoxide has been demonstrated. A wide range of structurally varied acetates have been subjected to deprotection by this procedure to give the corresponding alcohols m high yields. This procedure offers remarkable selectivity for deprotection of acetate over benzoate, <em>p</em>-nitrobenzoate and allyl, benzyl, TBDMS and THP ethers.
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Chapman, Erin E., and Richard F. Langler. "Selective deprotection of phenolic polysulfonates." Journal of Sulfur Chemistry 31, no. 1 (2010): 19–26. http://dx.doi.org/10.1080/17415990903295694.

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Nelson, Todd D., and R. David Crouch. "Selective Deprotection of Silyl Ethers." Synthesis 1996, no. 09 (1996): 1031–69. http://dx.doi.org/10.1055/s-1996-4350.

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Crouch, R. David. "Selective deprotection of silyl ethers." Tetrahedron 69, no. 11 (2013): 2383–417. http://dx.doi.org/10.1016/j.tet.2013.01.017.

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Naito, Hiroyuki, Takeshi Hata, and Hirokazu Urabe. "Selective Deprotection of Methanesulfonamides to Amines." Organic Letters 12, no. 6 (2010): 1228–30. http://dx.doi.org/10.1021/ol100086j.

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Costello, Colleen A., Adam J. Kreuzman, and Milton J. Zmijewski. "Selective deprotection of phthalyl protected amines." Tetrahedron Letters 37, no. 42 (1996): 7469–72. http://dx.doi.org/10.1016/0040-4039(96)01752-2.

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Pavan Kumar, G., D. Rambabu, M. V. Basaveswara Rao, and Manojit Pal. "Iodine-Mediated Neutral and SelectiveN-Boc Deprotection." Journal of Chemistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/916960.

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A simple, efficient, and alternative method has been developed for theN-Boc deprotection of structurally diverse protected amines. Selective removal ofN-Boc groups was achieved with excellent yields under a solvent-free condition or in a solvent using iodine as a catalyst. The methodology involving the first use of iodine forN-Boc deprotection of protected amines represents an effective and useful alternative to the previously reported methods.
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Swamy, V., Palanichamy Ilankumaran, and Srinivasan Chandrasekaran. "Selective Deprotection of Propargyl Ethers Using Tetrathiomolybdate." Synlett 1997, Sup. I (1997): 513–14. http://dx.doi.org/10.1055/s-1997-6132.

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Jones, Graham B., George Hynd, Justin M. Wright, and Anu Sharma. "On the Selective Deprotection of Trityl Ethers." Journal of Organic Chemistry 65, no. 1 (2000): 263–65. http://dx.doi.org/10.1021/jo9913255.

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Akai, Shoji, Rika Tanaka, Hidekazu Hoshi, and Ken-ichi Sato. "Selective Deprotection Method of N-Phenylcarbamoyl Group." Journal of Organic Chemistry 78, no. 17 (2013): 8802–8. http://dx.doi.org/10.1021/jo4007128.

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Dissertations / Theses on the topic "Selective deprotection"

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Sahloul, Kamar. "Vers l’étude de la spécificité d’enzymes de biosynthèse des HS : développement de méthodologies pour la synthèse de fragments de structure bien définie." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA112233.

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Les Héparanes sulfates (HS) appartiennent à la famille des glycosaminoglycanes (GAGs) qui sont des polysaccharides existants sur la surface cellulaire ou dans la matrice extracellulaire des cellules animales. Les GAGs jouent des rôles essentiels dans plusieurs processus biologiques via leurs interactions avec certaines protéines (chemokines, cytokines, facteurs de croissance, enzymes…) dont ils modulent les activités biologiques. Ils sont constitués par la répétition d’un motif disaccharidique de base comportant un acide uronique lié à un 2-amino-sucre. Une diversité moléculaire considérable p
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Yen, Shih-Yao, and 顏士堯. "2-(Acetylsulfanyl)methyl Benzoate and 4-Acetoxybenzyl Carbonate: Two New Orthogonal Protecting Groups, and Selective Deprotection by Ytterbium(III) Triflate." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/exan3u.

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碩士<br>國立中興大學<br>化學系所<br>107<br>The concept of orthogonality has become a mainstream for development of building blocks to carbohydrate synthesis. In this work, we developed two new orthogonal protecting groups for carbohydrates, namely 4-Acetoxybenzyl Carbonate (ABC) and 2-(Acetylsulfanyl)methyl Benzoate (ASMB). Both of them can be efficiently installed into different carbohydrate glycosides. Moreover, the two protecting groups can be selectively removed using Ytterbium(III) trifluoromethanesulfonate [Yb(OTf)3] under mild reaction conditions. The ABC group was selectively removed by deprotecti
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Peixoto, Catarina Soares. "New methodology for the synthesis of β-substituted-alcohols". Master's thesis, 2013. http://hdl.handle.net/10451/29634.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2014<br>β-fluoro alcohols are an important class of natural and synthetic molecules with biological activity as, for example, antibacterial and antiviral drugs, and caspase inhibitors, and are used as precursors for the preparation of other drugs. Diols and polyols have demonstrated over the years to be useful building blocks, but their use is often subdued by the assistance of protecting groups. Protecting groups are fundamental in organic synthesis, being common their use in synthes
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Tsai, Fu-Yuan, and 蔡福源. "I. Study of Photo-induced DNA Cleavages by an Azulenequinone II. Development of Ceric Ammoninum Nitrate as a Selective Deprotecting Reagent." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/48265122568882415622.

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博士<br>國立清華大學<br>化學系<br>91<br>I. Study of Photo-induced DNA Cleavages by an Azulenequinone II. Development of Ceric Ammoninum Nitrate as a Selective Deprotecting Reagent Abstract In this dissertation, I report new and controllable photo-induced DNA cleaving processes by use of an azulenequinone under aerobic conditions. I also report the DNA cleavage pattern resulting from this compound under photolytical conditions. Furthermore, silica gel—supported ceric ammonium nitrate was found effective for rapid and selective cleavage of tert-butyldim
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Book chapters on the topic "Selective deprotection"

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Cavelier, Florine, Valérie Lejeune, and Jean Martinez. "Towards a Selective Boc Deprotection on Acid Cleavable Resin." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_35.

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Kaiser, Emil, Teresa M. Kubiak, James P. Tam, and R. B. Merrifield. "Chlorotrimethylsilane-phenol as a selective deprotection reagent for the tert-butyloxycarbonyl group." In Peptides. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_70.

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Robertson, Jeremy, and Petra M. Stafford. "Selective Hydroxyl Protection and Deprotection." In Carbohydrates. Elsevier, 2003. http://dx.doi.org/10.1016/b978-012312085-4/50004-0.

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Robertson, Jeremy. "Silyl protecting groups." In Protecting Group Chemistry. Oxford University Press, 2000. http://dx.doi.org/10.1093/hesc/9780198502753.003.0004.

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This chapter evaluates silyl protecting groups. To categorise silicon protecting groups as either acid or base-labile is impractical because both types of cleavage are possible and find routine use. Organosilicon chemistry is characterised by a high affinity for oxygen, which has led to the widespread use of silyl ethers for the protection of alcohols, and higher affinity for fluorine, which provides a very selective deprotection pathway. The chapter then looks at alcohols, diols, aldehydes and ketones, and amines. Deprotection of silyl protecting groups with F<sup>-</sup>ion is normally highl
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Ward, Robert S. "Selective protection of bifunctional compounds." In Bifunctional Compounds. Oxford University Press, 1994. http://dx.doi.org/10.1093/hesc/9780198558088.003.0010.

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This chapter addresses a problem which frequently arises with a molecule that contains two reactive functional groups: how can one carry out a selective reaction on one group without affecting the other? It clarifies how acetals can be used to protect aldehyde or ketone groups while transformations are carried out elsewhere in a molecule. It also implies that acetals can be used to protect diols and simple alcohols, noting that they are often preferable to simple ether protecting groups as they can be removed under very mild conditions. The chapter points out that tetrahydropyranyl and methoxy
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David, Serge. "Reactions of hydroxyl groups." In The Molecular and Supramolecular Chemistry of Carbohydrates: Chemical Introduction to the Glycosciences. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198500476.003.0005.

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Abstract In the majority of sugars, all carbons are functional. When a particular function is to be modified using traditional organic chemistry methods, the other functions need to be ‘protected’. This means they are first transformed into derivatives that are inert under the desired reaction conditions, then reconverted into the starting function during a subsequent step. This last phase is called the ‘deprotection’ step. It is often useful to protect diverse functions of the same molecule by derivatizations of a different nature in order to effect selective deprotections. We have already en
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Taber, Douglass F. "The Bradshaw/Bonjoch Synthesis of (-)-Anominine." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0097.

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The Hajos-Parrish cyclization was a landmark in the asymmetric construction of polycarbocyclic natural products. Impressive at the time, the proline-mediated intramolecular aldol condensation proceeded with an ee that was low by modern standards. Ben Bradshaw and Josep Bonjoch of the Universitat de Barcelona optimized this protocol, then used it to prepare (J. Am. Chem. Soc. 2010, 132, 5966) the enone 3 en route to the Aspergillus alkaloid (-)-anominine 4. The optimized catalyst for the enantioselective Robinson annulation was the amide 5 . With 2.5 mol % of the catalyst, the reaction proceede
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Lambert, Tristan H. "Functional Group Protection." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0013.

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Martin D. Burke at the University of Illinois at Urbana-Champaign reported (Nature Chem. 2012, 4, 996) that the amphotericin B derivative 1 could be site-selectively acylated at the C15, C4′, or C2′ hydroxyls by electronic tuning of the acylating agent (e.g., 2 leading to 3). Another impressive example of selective protection was disclosed (Nature Chem. 2012, 4, 789) by Andreas Herrmann at the Zernike Institute for Advanced Materials, who found that RNA aptamers such as 5 selectively bind to neomycin 4, leaving only one of the amino groups exposed for acylation to selectively furnish, for exam
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Taber, Douglass F. "The Trost Synthesis of (−)-Lasonolide A." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0093.

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(−)-Lasonolide A 4, isolated from the Caribbean sponge Forcepia sp., showed remarkable anticancer activity in the NIH 60-cell screen. The central step in the syn­thesis of 4 reported (J. Am. Chem. Soc. 2014, 136, 88) by Barry M. Trost of Stanford University was the remarkably selective, convergent Ru-mediated coupling of 1 with 2 to give 3. To prepare 1, the authors took advantage of the underutilized Cu-mediated addi­tion of a Grignard reagent 6 to propargyl alcohol 5, to give 7. Coupling with the ace­tonide 8 followed by deprotection led to the phosphonium salt 9. The other half of 1 was pre
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Taber, Douglass F. "The Snyder Synthesis of Psylloborine A." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0099.

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In addition to the monomeric coccinellid alkaloids produced by the ladybug, some dimeric alkaloids, exemplified by psylloborine A 3, have been isolated. Scott A. Snyder of Scripps/Florida initially attempted a direct dimerization strategy for the assembly of 3, but when that failed, he devised (J. Am. Chem. Soc. 2014, 136, 9743) a route to the tethered dimer 1, that could indeed be cyclized to 2, the immediate precursor to 3. The starting material for both 9, the lower half of 1, and 13, the upper half of 1, was the commercial, enantiomerically-pure piperidine 4. Metalation followed by allylat
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Conference papers on the topic "Selective deprotection"

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Firouzabadi, Habib, Hassan Hazarkhani, Babak Karimi, Uranous Niroumand, and Soheila Ghassamipour. "Selective Deprotection of Thioacetals by MnO2, BaMnO4 and KMnO4 in the Presence of Anhydrous AlCl3 and FeCl3 in Dry CH3CN." In The 4th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01824.

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Pogrebnoi, Vsevolod, Natalia Sucman, and Fliur Macaev. "The amides of dehydroabietic acid in synthesys of spiropyranes with the participation of carbonyl compounds." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab16.

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The abstract presents the synthesis of new spiropyranes from substituted 5-aminoisatin 6 in multicomponent reaction with different carbonyl compounds. It is known that spiropyranes have various activities, which depend from spatial structure and substituents [1]. From the other side, previously mentioned dehydroabietic acid 1 [2] is interesting object to study due to its molecular structure, chemical and biological properties.Initially, our strategy was to obtain the substituted isatine 6 from easily accessible isatine 3. To implement that approach, previously obtained [2] 5-nitroisatine react
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